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33. A chair-stand time of greater than 15 seconds is associated with an increased risk of death and hospitalization in cirrhosis

Author

Nguyen, Vivian V, Wang, Sarah, Whitlock, Reid, Xu, Chelsea, Taneja, Sunil, Singh, Surender, Abraldes, Juan G, Burak, Kelly, Bailey, Robert J, Grab, Joshua D, Lai, Jennifer C, and Tandon, Puneeta

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Liver Disease, Clinical Research, Digestive Diseases, Good Health and Well Being, cirrhosis, frailty, mortality
Abstract

BackgroundFrailty is a clinical state of increased vulnerability and is common in patients with cirrhosis. The liver frailty index (LFI) is a validated tool to evaluate frailty in cirrhosis, comprising of grip strength, chair stands, and balance tests. The chair-stand test is an easy to conduct frailty subcomponent that does not require specialized equipment and may be valuable to predict adverse clinical outcomes in cirrhosis. The objective of this study was to determine if the chair-stand test is an independent predictor of mortality and hospitalization in cirrhosis.MethodsA retrospective review of 787 patients with cirrhosis was conducted. Chair-stand times were collected at baseline in person and divided into three groups: 15 seconds (n = 221). Fine-Gray proportional hazards regression models were used to evaluate the association between chair-stand times and the outcomes of mortality and non-elective hospitalization.ResultsThe hazard of mortality (HR 3.21, 95% CI 2.16%-4.78%, p 15 seconds had increased all-cause mortality (HR 2.78, 95% CI 2.01%-3.83%, p 15 seconds is independently associated with mortality and non-elective hospitalizations. This test holds promise as a rapid prognostication tool in cirrhosis. Future work will include external validation and virtual assessment in this population.

Published
2023

34. Book Review

Author

Singh, Surender

Published
2018

40. Sustainable Growth of Automobile Industry in India

Author

Singh, Surender, Kumar, Krishan, Mishra, Om Prakash, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Bhardwaj, Arvind, editor, Pandey, Pulak Mohan, editor, and Misra, Aviral, editor

Published
2024
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41. Bibliometric Analysis of Green Manufacturing in Automobile Sector

Author

Singh, Surender, Mishra, Omprakash, Kumar, Krishan, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Bhardwaj, Arvind, editor, Pandey, Pulak Mohan, editor, and Misra, Aviral, editor

Published
2024
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44. Structural phase transitions in perovskite BaCeO3 revisited by data mining-cum-first-principles theoretical approaches

Author

Naaz, Farha, Chauhan, Manendra S., Yadav, Kedar, Singh, Surender, Kumar, Ashok, and Prasad, Dasari L. V. K.

Subjects
Condensed Matter - Materials Science
Abstract

Several experiments conducted over decades have revealed that the perovskite-structured BaCeO3 goes through a series of temperature-induced structural phase transitions. However, it has been frequently observed that the number of phases and the sequence in which they appear as a function of temperature differ between experiments. Insofar as neutron diffraction and Raman spectroscopy experiments are concern, four structures are well characterized with three transitions: Pnma to Imma [563 K] to R-3c [673 K] to Pm-3m [1173 K]. In contrast, thermoanalytical methods showed multiple singularities corresponding to at-least three more structural transitions at around 830 K, 900 K, and 1030 K. In account of these conflicting experimental findings, we computed free energy phase diagram for BaCeO3 employing crystal structure data mining in conjunction with first principles electronic structure and phonon lattice dynamics. A total of 34 polymorphs have been predicted, the most stable of which follows the Glazer classification of the perovskite tilt system. It has been predicted that the Cmcm and P4/mbm phases surpass Pnma at 666 K and 1210 K, respectively. At any temperature, two alternate tetragonal phases (P42/nmc and I4/mcm) are also found to be 20 to 30 meV less favored than the Pnma. While the calculated stability order of the predicted polymorphs is in acceptable agreement with the results of neutron diffraction, the transitions observed in thermoanalytical studies could be ascribed to the development of four novel phases (Cmcm, P4/mbm, P42/nmc, and I4/mcm) at intermediate temperatures. However, we analyze that the R-3c phase predominantly stabilized over a broad temperature field, masking all subsequent phases up until the cubic Pm-3m. Consequently, the novel phases predicted to occur in thermoanalytical studies are only fleetingly metastable., Comment: 20 pages, 5 figures

Published
2023

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