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6. Fresh and Cryopreserved Arterial Homografts in the Treatment of Prosthetic Graft Infections: Experience of the Italian Collaborative Vascular Homograft Group

Author

Chiesa, R., Astore, D., Piccolo, G., Melissano, G., Jannello, A., Frigerio, D., Agrifoglio, G., Bonalumi, F., Corsi, G., Costantini Brancadoro, S., Novali, C., Locati, P., Odero, A., Pirrelli, S., Cugnasca, M., Biglioli, P., Sala, A., Polvani, G., Guarino, A., Biasi, G.M., Mingazzini, P., Scalamogna, M., Mantero, S., Spina, G., Prestipino, F., and Sirchia, G.

Published
1998
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37. Fresh and cryopreserved arterial homografts in the treatment of prostetic graft infections: experience of the Italian Collaborative Vascular Homograft Group

Author

Chiesa, R, Astore, D, Piccolo, G, Melissano, G, Jannello, A, Frigerio, D, Agrifoglio, G, Bonalumi, F, Corsi, G, Costantini Brancadoro, S, Novali, C, Locati, P, Odero, A, Pirrelli, S, Cugnasca, M, Biglioli, P, Sala, A, Polvani, G, Guarino, A, Biasi, G, Mingazzini, P, Scalamogna, M, Mantero, S, Spina, G, Prestipino, F, Sirchia, G, Sirchia, G., BIASI, GIORGIO MARIA, MINGAZZINI, PAOLO, Chiesa, R, Astore, D, Piccolo, G, Melissano, G, Jannello, A, Frigerio, D, Agrifoglio, G, Bonalumi, F, Corsi, G, Costantini Brancadoro, S, Novali, C, Locati, P, Odero, A, Pirrelli, S, Cugnasca, M, Biglioli, P, Sala, A, Polvani, G, Guarino, A, Biasi, G, Mingazzini, P, Scalamogna, M, Mantero, S, Spina, G, Prestipino, F, Sirchia, G, Sirchia, G., BIASI, GIORGIO MARIA, and MINGAZZINI, PAOLO

Abstract

Following the experience of cardiac surgeons with homografts in the treatment of infective aortic valve endocarditis, cardiovascular surgeons have investigated in situ revascularization by means of homografts in the management of vascular prosthetic graft infections. Preliminary results are encouraging, but their late fate in long-term follow-up and the influence of preservation techniques are still under investigation. This article reports the experience of the Italian Collaborative Vascular Homograft Group, with the use of fresh and cryopreserved arterial homografts for the treatment of prosthetic graft infections. Between March 1994 and December 1996, 44 patients with prosthetic graft infection were treated with homografts (13 preserved at 4°C, 31 cryopreserved). The mean age of the patients was 65 years. Emergency surgical procedures were performed in eight patients (18%). Sepsis was diagnosed in 11 patients, aortoenteric fistula in 13, and false aneurysms in 10. Staphylococcus was the main cause of infection. The types of vascular reconstruction with homograft were: 32 aortobifemoral, 3 aortoaortic, 2 iliofemoral, 4 peripheral, and 3 axillobifemoral. Human lymphocyte antigen (HLA) and antibody (ABO) blood group system compatibility between donors and recipients was not respected. The mean duration of follow-up was 15 months (range 1–33). Clinical and duplex scanning evaluations were routinely performed. Computed tomography (CT) or magnetic resonance (MR) scanning or arteriography were performed on the basis of duplex scanning results. There were six deaths during the early postoperative period (30 days) with a mortality rate of 13.6%. During the follow-up there were five late deaths with a mortality rate of 11.4%. Eight patients had graft occlusion. Three cases were successfully treated with thrombectomy. Two cases were successfully treated with femoropopliteal bypass with autologous vein. In three cases leg amputation was necessary. The results of fresh and cr

Published
1998

38. POSTOPERATIVE ARTERIAL INFECTION: EPIDEMIOLOGY, BACTERIOLOGY AND PATHOGENESIS

Author

CHIESA , ROBERTO, MELISSANO, GERMANO, Castellano R, Astore D, Frigerio S, Garriboli L, Gesu GP, Anzuini A, Piccolo G, Sirchia G, Scalamogna M., Branchereau A, Jacobs M, Chiesa, Roberto, Melissano, Germano, Castellano, R, Astore, D, Frigerio, S, Garriboli, L, Gesu, Gp, Anzuini, A, Piccolo, G, Sirchia, G, and Scalamogna, M.

Published
2001

39. Postoperative arterial infection:epidemiology, bacteriology, and pathogenesis

Author

Chiesa R, Castellano R, Astore D, Frigerio S, Garriboli L, Gesu GP, Anzuini A, Piccolo G, Sirchia G, Scalamogna M., MELISSANO , GERMANO, Branchereau A, Jacobs M, Chiesa, R, Melissano, Germano, Castellano, R, Astore, D, Frigerio, S, Garriboli, L, Gesu, Gp, Anzuini, A, Piccolo, G, Sirchia, G, and Scalamogna, M.

Published
2001

40. Arterial homograft replacement for aortic prosthetic graft infections

Author

Chiesa R, Astore D, Piccolo G, Jannello A, Frigerio S, Castellano R, Odero A, Biglioli P, Costantini Brancadoro S, Agrifoglio G, Spina G, Ruberti U, Sirchia G, for the Italian Collaborative Vascular Homograft Group, Mailand, MELISSANO , GERMANO, Chiesa, R, Astore, D, Piccolo, G, Melissano, Germano, Jannello, A, Frigerio, S, Castellano, R, Odero, A, Biglioli, P, Costantini Brancadoro, S, Agrifoglio, G, Spina, G, Ruberti, U, Sirchia, G, for the Italian Collaborative Vascular Homograft, Group, and Mailand

Published
2000

41. Chronic hepatitis c virus infection and primary cutaneous B-cell lymphoma

Author

Prati, D, Zanella, A, De Mattei, C, Farma, E, Boschetti, C, Sirchia, G, Venegoni, L, Berti, E., Prati, D, Zanella, A, De Mattei, C, Farma, E, Boschetti, C, Sirchia, G, Venegoni, L, and Berti, E

Subjects
Hepatitis Antibodie, Lymphoma, B-Cell, Skin Neoplasms, MED/15 - MALATTIE DEL SANGUE, MED/35 - MALATTIE CUTANEE E VENEREE, Humans, Skin Neoplasm, Hepatitis Antibodies, Hepatitis C, Chronic, Human
Published
1999

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