165 results on '"Skarpen, Ellen"'
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2. Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
3. Remodeling of secretory lysosomes during education tunes functional potential in NK cells
4. The effect of the chemical chaperone 4-phenylbutyrate on secretion and activity of the p.Q160R missense variant of coagulation factor FVII
5. Developmental neurotoxicity of acrylamide and its metabolite glycidamide in a human mixed culture of neurons and astrocytes undergoing differentiation in concentrations relevant for human exposure
6. Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome
7. Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
8. Early Cellular Alterations in Chemical Liver Carcinogenesis as Assessed by Immunohistochemical and Molecular Biological Techniques
9. Predictive biomarkers for 5‐ALA‐PDT can lead to personalized treatments and overcome tumor‐specific resistances.
10. The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
11. The Factor VII Variant p.A354V-p.P464Hfs: Clinical versus Intracellular and Biochemical Phenotypes Induced by Chemical Chaperones
12. The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
13. Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
14. Regulation of rat alveolar type 2 cell proliferation in vitro involves type II cAMP-dependent protein kinase
15. The PtdIns3P-Binding Protein Phafin 2 Mediates Epidermal Growth Factor Receptor Degradation by Promoting Endosome Fusion
16. Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
17. Characterizing Coagulation FVII from iPSC-Hepatocytes-like Cells: Setting the Basis for Cell Therapy Development
18. Predictive biomarkers for 5‐ALA‐PDT can lead to personalized treatments and overcome tumor‐specific resistances
19. Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures
20. MOESM1 of The effect of the chemical chaperone 4-phenylbutyrate on secretion and activity of the p.Q160R missense variant of coagulation factor FVII
21. CCAAT/enhancer-binding protein (C/EBP) immunoreactivity during rat liver carcinogenesis
22. Cytoplasmic Retention of Peroxide-Activated ERK Provides Survival in Primary Cultures of Rat Hepatocytes*
23. Gene Activation Studied by Immunological Methods
24. MOESM1 of The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
25. Unrestrained ESCRT-III drives chromosome fragmentation and micronuclear catastrophe
26. Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit
27. The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
28. The Chemical Chaperone 4-Phenylbutyrate Increases Secretion and Activity of Missense and Elongated Factor VII Mutants
29. Modulation of Secretory Lysosomes During NK Cell Education Leads to Accumulation of Granzyme B and Enhanced Functional Potential
30. Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency
31. Factor VII deficiency: Unveiling the cellular and molecular mechanisms underlying three model alterations of the enzyme catalytic domain
32. The chemical chaperone sodium 4-phenylbutyrate improves the secretion of the protein CA267T mutant in CHO-K1 cells trough the GRASP55 pathway
33. Isolation and mass spectrometry analysis of urinary extraexosomal proteins
34. Abstract A18: The tankyrase inhibitor G007-LK inhibits small intestine Lgr5+ stem cell proliferation without altering tissue morphology
35. The tankyrase inhibitor G007-LK inhibits small intestine LGR5+stem cell proliferation without altering tissue morphology
36. Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
37. Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer
38. Photochemical Internalization of Tamoxifens Transported by a “Trojan-Horse” Nanoconjugate into Breast-Cancer Cell Lines
39. Abstract 3032: The effect of a tankyrase inhibitor on the small intestine tissue homeostasis
40. Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
41. FAK regulates Cdk2 in EGF‐stimulated primary cultures of hepatocytes
42. EGF Activates Autocrine TGFα to Induce Prolonged EGF Receptor Signaling and Hepatocyte Proliferation
43. EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase
44. Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit
45. Distinct functions of H-Ras and K-Ras in proliferation and survival of primary hepatocytes due to selective activation of ERK and PI3K
46. MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments
47. The chemical chaperone sodium 4-phenylbutyrate improves the secretion of the protein CA267T mutant in CHO-K1 cells trough the GRASP55 pathway.
48. Fluorescent Histochemical Techniques for Analysis of Intracellular Signaling
49. UV induces tyrosine kinase-independent internalisation and endosome arrest of the EGF receptor
50. Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF
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