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9. High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership.

Author

Carlucci, Philip M, Li, Jessica, Fava, Andrea, Deonaraine, Kristina K, Wofsy, David, James, Judith A, Putterman, Chaim, Diamond, Betty, Davidson, Anne, Fine, Derek M, Monroy-Trujillo, Jose, Atta, Mohamed G, DeJager, Wade, Guthridge, Joel M, Haag, Kristin, Rao, Deepak A, Brenner, Michael B, Lederer, James A, Apruzzese, William, Belmont, H Michael, Izmirly, Peter M, Zaminski, Devyn, Wu, Ming, Connery, Sean, Payan-Schober, Fernanda, Furie, Richard, Dall’Era, Maria, Cho, Kerry, Kamen, Diane, Kalunian, Kenneth, Anolik, Jennifer, Barnas, Jennifer, Ishimori, Mariko, Weisman, Michael H, Goff, Jennifer, Dunn, Patrick J, Raychaudhuri, Soumya, Zhang, Fan, Korsunsky, Ilya, Nathan, Aparna, Mears, Joseph, Ishigaki, Kazuyoshi, Xiao, Qian, Millard, Nghia, Weinand, Kathryn, Sakaue, Saori, Utz, PJ, Mao, Rong, Robinson, Bill, Maecker, Holden, Macwana, Susan, Bridges, S Louis, Bykerk, Vivian, Donlin, Laura, Goodman, Susan, DiCarlo, Edward, Smith, Melanie, Lakhanpal, Amit, Sherman, Heather, Singaraju, Anvita, Shakib, Lorien, Ritchlin, Christopher, Boyce, Brendan, Tabechian, Darren, McDavid, Andrew, Rangel-Moreno, Javier, Meednu, Nida, Albrecht, Jen, Wei, Kevin, Helena Jonsson, A, Simmons, Daimon, Keras, Gregory, Keegan, Joshua, Watts, Gerald, Li Zhu, Yuhong, Chicoine, Adam, Jian Li, Zhihan, Gravallese, Ellen M, Howard, Kaitlyn, McGeachy, Mandy, Firestein, Gary S, Boyle, David L, Ceponis, Arnold, Gregersen, Peter K, Horowitz, Diane, Perlman, Harris, Dominguez, Salina, Cuda, Carla M, Mandolin, Arthur M, Thakrar, Anjali, Bathon, Joan M, Hughes, Laura, Michael Holers, V, Seifert, Jennifer, Deane, Kevin, Moreland, Larry W, Filer, Andrew, Raza, Karim, Sahbudin, Ilfita, and Pitzalis, Costantino

Subjects
Clinical Research, Kidney Disease, Lupus, Autoimmune Disease, Humans, Lupus Nephritis, Prospective Studies, Incidence, Proteinuria, Kidney Function Tests, Kidney, systemic lupus erythematosus, lupus nephritis, diagnosis, Accelerating Medicines Partnership (AMP) RA/SLE Network, Clinical Sciences, Immunology, Public Health and Health Services, Arthritis & Rheumatology
Abstract

ObjectiveDelayed detection of LN associates with worse outcomes. There are conflicting recommendations regarding a threshold level of proteinuria at which biopsy will likely yield actionable management. This study addressed the association of urine protein:creatinine ratios (UPCR) with clinical characteristics and investigated the incidence of proliferative and membranous histology in patients with a UPCR between 0.5 and 1.MethodsA total of 275 SLE patients (113 first biopsy, 162 repeat) were enrolled in the multicentre multi-ethnic/racial Accelerating Medicines Partnership across 15 US sites at the time of a clinically indicated renal biopsy. Patients were followed for 1 year.ResultsAt biopsy, 54 patients had UPCR

Published
2022

12. Student Autonomy of Feedback Format in Higher Education and Perceived Functional Behaviours for Academic Development

Author

Sparrow, Abby, Smith, Samantha, Petronzi, Dominic, Wilson, Helen, Roeschlaub, Sarah, and Smith, Melanie

Abstract

In the current context of promoting active learning and raising student engagement within Higher Education, an increasing amount of research has looked at pedagogical-based design and factors that contribute to functional behaviours surrounding the interaction and use of academic assessment feedback. However, few studies have considered the perceived influence of student autonomy over feedback format and whether this promotes engagement and academic development. In this study, we recruited level 5 and 6 students (N=38) on an undergraduate Education Programme (that has consistently implemented student feedback choice) to participate in initial self-reporting and subsequent focus groups ('soft triangulation'). The findings revealed three core themes: [1] Personalisation -- (a) "sense of autonomy/involvement," (b) "engagement" and (c) "motivation," [2] Clarity -- (d) "depth and detail," and [3] Areas for development. Overall, these findings suggest that feedback type -- and the inherent option to choose -- has a functional impact on academic engagement and development. We discuss these findings in relation to a sense of being valued that was associated with autonomy of choice, a divergence in how and when students engage with feedback, as well as the requirement for academic clarity and provision of formats that support academic development.

Published
2020

14. RT-PCR genotyping assays to identify SARS-CoV-2 variants in England in 2021: a design and retrospective evaluation study

Author

Bray, Neil, Sopwith, Will, Edmunds, Matt, Vansteenhouse, Harper, Feenstra, Jelena D M, Jacobs, Peter, Rajput, Kamal, O’Connell, Anne Marie, Smith, Melanie L, Blomquist, Paula, Hatziioanou, Diane, Elson, Richard, Vivancos, Roberto, Gallagher, Eileen, Wigglesworth, Mark J, Dominiczak, Anna, Hopkins, Susan, and Lake, Iain R

Published
2024
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18. Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network

Author

Deonaraine, Kristina K, Carlucci, Philip M, Fava, Andrea, Li, Jessica, Wofsy, David, James, Judith A, Putterman, Chaim, Diamond, Betty, Davidson, Anne, Fine, Derek M, Monroy-Trujillo, Jose, Atta, Mohamed G, Haag, Kristin, Rao, Deepak A, Apruzzese, William, Belmont, H Michael, Izmirly, Peter M, Wu, Ming, Connery, Sean, Payan-Schober, Fernanda, Furie, Richard A, Berthier, Celine C, Dall'Era, Maria, Cho, Kerry, Kamen, Diane L, Kalunian, Kenneth, Anolik, Jennifer, Ishimori, Mariko, Weisman, Michael H, Petri, Michelle A, Buyon, Jill P, Goff, Jennifer, Dunn, Patrick, Raychaudhuri, Soumya, Zhang, Fan, Korsunsky, Ilya, Nathan, Aparna, Mears, Joseph, Ishigaki, Kazuyoshi, Xiao, Qian, Millard, Nghia, Weinand, Kathryn, Sakaue, Saori, Utz, PJ, Mao, Rong, Robinson, Bill, Maecker, Holden, Guthridge, Joel, DeJager, Wade, Macwana, Susan, Bridges, Louis, Bykerk, Vivian, Donlin, Laura, Goodman, Susan, DiCarlo, Edward, Smith, Melanie, Lakhanpal, Amit, Sherman, Heather, Singaraju, Anvita, Shakib, Lorien, Ritchlin, Christopher, Boyce, Brendan, Tabechian, Darren, McDavid, Andrew, Rangel-Moreno, Javier, Meednu, Nida, Albrecht, Jen, Brenner, Michael, Lederer, James, Wei, Kevin, Jonsson, A Helena, Simmons, Daimon, Keras, Gregory, Keegan, Joshua, Watts, Gerald, Li, Yuhong, Zhu, Zhu, Chicoine, Adam, Li, Zhihan Jian, McGeachy, Mandy, Firestein, Gary, Boyle, David, Ceponis, Arnold, Gregersen, Peter, Horowitz, Diane, Perlman, Harris, Dominguez, Salina, Cuda, Carla, Mandelin, Arthur, Thakrar, Anjali, Bathon, Joan, Hughes, Laura, Holers, Mike, Seifert, Jennifer, Deane, Kevin, Moreland, Larry, Filer, Andrew, Raza, Karim, Sahbudin, Ilfita, and Pitzalis, Constanino

Subjects
Autoimmune Disease, Patient Safety, Kidney Disease, Lupus, Clinical Research, Renal and urogenital, Arteriovenous Fistula, Biopsy, Hematoma, Humans, Kidney, Lupus Nephritis, United States, lupus nephritis, lupus erythematosus, systemic, autoimmunity, Accelerating Medicines Partnership RA/SLE network
Abstract

In lupus nephritis the pathological diagnosis from tissue retrieved during kidney biopsy drives treatment and management. Despite recent approval of new drugs, complete remission rates remain well under aspirational levels, necessitating identification of new therapeutic targets by greater dissection of the pathways to tissue inflammation and injury. This study assessed the safety of kidney biopsies in patients with SLE enrolled in the Accelerating Medicines Partnership, a consortium formed to molecularly deconstruct nephritis. 475 patients with SLE across 15 clinical sites in the USA consented to obtain tissue for research purposes during a clinically indicated kidney biopsy. Adverse events (AEs) were documented for 30 days following the procedure and were determined to be related or unrelated by all site investigators. Serious AEs were defined according to the National Institutes of Health reporting guidelines. 34 patients (7.2%) experienced a procedure-related AE: 30 with haematoma, 2 with jets, 1 with pain and 1 with an arteriovenous fistula. Eighteen (3.8%) experienced a serious AE requiring hospitalisation; four patients (0.8%) required a blood transfusion related to the kidney biopsy. At one site where the number of cores retrieved during the biopsy was recorded, the mean was 3.4 for those who experienced a related AE (n=9) and 3.07 for those who did not experience any AE (n=140). All related AEs resolved. Procurement of research tissue should be considered feasible, accompanied by a complication risk likely no greater than that incurred for standard clinical purposes. In the quest for targeted treatments personalised based on molecular findings, enhanced diagnostics beyond histology will likely be required.

Published
2021

23. Race-related Differences in Sipuleucel-T Response Among Men with Metastatic Castrate-Resistant Prostate Cancer

Author

Heath, Elisabeth I., primary, Thakur, Archana, additional, Chen, Wei, additional, Hwang, Clara, additional, Paller, Channing J., additional, Cackowski, Frank C, additional, Boerner, Julie L., additional, Heilbrun, Lance, additional, Smith, Melanie P., additional, Schalk, Dana L., additional, Schienschang, Amy, additional, Whitaker, Sarah A., additional, Polend, Amanda, additional, Smith, Daryn, additional, Vaishampayan, Ulka N., additional, Dickow, Brenda, additional, and Lum, Lawrence G., additional

Published
2024
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24. [Reviews]

Author

Bullen, Sally and Smith, Melanie

Published
2000

25. [Reviews]

Author

Bullen, Sally and Smith, Melanie

Published
1999

33. Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study

Author

Dunning, Jake, Fink, Douglas L, Milligan, Iain D, Luintel, Akish, Rodger, Alison J, Bhagani, Sanjay R, Lamb, Lucy E, Moores, Rachel C, Lee, Simon F K, Brown, Colin S, Hopkins, Susan, Mepham, Stephen, Warren, Simon, Molloy, Aoife, Cropley, Ian, Kew, Alex, Karunaharan, Natasha, Scobie, Antonia, Hart, Jennifer, Irish, Dianne, Haque, Tanzina, Jalal, Hamid, Smith, Robin, Mack, Damien, Barber, Tristan, Burns, Fiona, Miller, Robert, Hamlyn, Eleanor, Simoes, Pedro, Athan, Breda, Abrahamsen, Jennifer, Joyce, Jessica, Taylor, Caroline, Reddecliffe, Sally, Miller, Chloe, Reeve, Brooke, Kingston, Hugh, Crocker-Buque, Tim, Massie, Nicolas, Dhariwal, Ankush, Jayakumar, Angelina, Hammond, Robert, Bramley, Alexandra, Kanitkar, Tanmay, Maynard-Smith, Laura, Gil, Eliza, O'Connor, Cavan, Cocker, Derek, Spicer, Wendy, Lanzman, Marisa, Thacker, Meera, Anorson, Zoe O, Patel, Dharmesh, Williams, Alan, Houlihan, Catherine F, Wakerley, Dominic, Gordon, Claire N, Callaby, Helen, Bailey, Daniel J, Furneaux, Jenna, Bown, Abbie M, Truelove, Elizabeth J, Killip, Marian J, Jackson, David, Beetar-King, Tracy L B, Arnold, Ulrike M V, Strachan, Rhea M, Matthew, Jones, Matthew, Hannah J, Osborne, Jane C, Rampling, Tommy, Vipond, Richard, Gibney, Barry, Owen, Jodie, Bond, Helena, Beynon, Will, Hunter, Michael, McCorry, Louise, Emerson, Carol, Quah, Say, Todd, Suzanne, McCarty, Emma, Walker, Eoin, Feeney, Susan, Curran, Tanya, Li, Kathy, Mullan, JD, Jackson, Kate, Nelson, Peter, Lewis, Kevin, McNicol, Mark, Pratt, Marcus, Smith, Anna, Vos, Erin, Alsalemee, Fahad, O Leary, Daniel, Canny, John, McGinnity, Katherine, Culbert, Carly, McDowell, Conor, McQuillan, Cathy, Jeong, Eunjin, Glass, Lynsey, Dyche, Jessica, McClean, Paula, Stewart, Rebecca, Ursolino, Harold, Perry, Melissa, McCormick, Hannah, Lim, Eleanor Y, Gkrania-Klotsas, Effrossyni, Bracchi, Margherita, Heskin, Joseph, Brown, Nicklas, Juniper, Thomas, Mora-Peris, Borja, Dalla-Pria, Alessia, Mackie, Nicola, Garvey, Lucy, Winston, Alan, Cooke, Graham, Nelson, Mark, Kilbride, Emer, Elbishi, Ala, Kerrigan, William, Silva, Joshua, Gohil, Jesal, Payagala, Sasha, Walters, Yasmin, Smith, Joanna, Goodfellow, Jonathan, Lyons, Kitty, Tung, Hsiu, Patel, Kinjal, Henderson, Merle, Butler, Michael, Peres, Edu, Silva Carvalho, Taiana, Joly, Antoine, Dickinson, Molly, Moore, Luke S P, Mughal, Nabeela, Hughes, Stephen, Chitlangia, Shrada, Viramgana, Priyanka, Byrne, Ruth, Randell, Paul, Strangis, Luigi, Poveda, Nicola, Bovey, Deborah, Richardson, Poppy, Heaslip, Vivian, Higgs, Christopher, Boffito, Marta, Girometti, Nicolo, Whitlock, Gary, Tittle, Victoria, Jones, Rachel, Rayment, Michael, Scott, Christopher, Asboe, David, Pond, Marcus, Muir, David, Rathish, Balram, O'Hara, Geraldine, Abeywickrema, Movin, Bailey, Sarah-Lou, Boyd, Sara E, Da Silva Fontoura, Dayana, Daunt, Anna, Mason, Claire Y, Murphy, Jamie, Naidu, Vasanth V, Patel, Aatish, Pley, Caitlin, Redmore, Ethan, Sharrocks, Katherine, Snell, Luke B, Sundramoorthi, Rohan, Tam, Jerry C H, Brown, Aisling, Douthwaite, Sam, Goodman, Anna, Nebbia, Gaia, Newsholme, William, Price, Nicholas, Shaw, Emily, Salam, Alex, van Nispen tot Pannerden, Claire, Winslow, Helen, Bilinska, Julia, Keegan, Sarah, Coleman, Harry, Doctor, Jessica, Moini, Nasreen, Chilton, Daniella, Haidari, Golaleh, Simons, Rebecca, Kulasegaram, Rajababu, Larbalestier, Nick, Nori, Achyuta, Potter, Jack R, Tuudah, Cecilia, Wade, Paul, Travers, Alexandra, Dunford, Sarah, Greenwood, Joshua, Oledimmah, Georgina, Gyampo, Lesley, SA Pinto, Pedro, Muse, AbdulKadir, Parker, Zoe, Alexander, Charlotte, Khan, Alexander, Ajayi, Medinat, Baltazar, Abigail, Sharella, Davis, Hersi, Nasra, Nguyen, Thuy, Timbo, Rugiatu, Jalloh, Ismail, Bryan, Susan, Clarke, Patricia, Kerr, Marcia, Amedu, Fidelis, BohoBonaba, Maria, Haque, Sarah, Howson, Michelle, Tambilawan, Norbai, Yupanqui Estay, Soledad, Bangura, Hawanatu, Gideon, Tseday, Jerome-oboh, Damilola, Tetteh, Linda, Nwagu, Chioma, Agbaglah, Viwoalo, Narag, Nona, Zaveri, Mahima, Ni Luanaigh, Maedhbh, Keane, Peggy, Peters, Joanna R, Rimmer, Stephanie, Abbara, Aula, Dosekun, Olamide, Bolland, Mhairi, Stafford, Adam, Saleh, Dina, Sheridan, Rhianna, Davies, Ella, Sun, Kristi, Gilchrist, Mark, Kukadia, Priti, Embrahimsa, Muhammed, Chiu, Christopher, Taylor, Lauren, Short, Charlotte, Alagratnam, Jasmini, Jayaweera, Iresh, Gundugola, Kavitha, Payne, Lara V S, Mody, Nisha, Quinn, Killian, Nic Fhogartaigh, Caoimhe, Kaur, Nivenjit, Bholah, Salmaan, Kantha, Kajann, Youngs, Jonathan, Lampejo, Temi, Pitto, Nicholas, Lawrence, David S, Middleditch, Holly, Dominguez-Dominguez, Lourdes, Ratnappuli, Ayoma, Al-Hashimi, Sara, Oliveira, Amelia, Ottaway, Zoe, Mulka, Larissa, Hodgson, Bethany, Lewthwaite, Penny, Neary, Anne M, Downey, Michael R, Lucy, Danielle C, McCallum, Craig I, Beadsworth, Michael, Ratcliffe, Libuse, Fletcher, Tom E, Davies, Gerry, Wong, Nicholas, Aston, Stephen, Wingfield, Thomas E, Blanchard, Thomas, Hine, Paul, Lester, Rebecca, Woolley, Stephen D, Gould, Susie, Smith, Christopher, Abouyannis, Michael, Atomode, Abolaji, Cruise, James, Samual, Merna, Scott, Nicola, Srirathan, Vino, Lewis, Joseph, Richards, Lauren, Cummings, Mary-Ann, Gillan, Emily, Peers, Rebecca, Tickle, Amy, Keating, Grace, Chinyanda, Tendi, Sanchez, Mav, Harrison, Daniel, Hoyle, Metcalfe, Ben, Taylor, Jennifer, Johnson, Nicky, Kelle, Neil, McDowell, Kirsty, Richardson, Ian, Saguidan, Monette, Farmer, Nicky, Gillespie, Angella, Willoughby, Shay, Parker, Samantha, Avulan, Shamseena, Arif, Shazia, Marshall, Suzanne, Carlisle, David, Rezaei, Mohsen, Booth, Angela, Watts, Joanne, Tremarco, Lauren, Jeyanayagam, Priyanga, Ubochi, Odinaka, Vagianos, Daniel, Richardson, Mark, Jarvis, Anthony, Gow, Kyra, Walmsley, Jade, O'keefe, Adam, Smielewska, Anna, Hopkins, Mark, Balane, Fatima, Bradley, Sarah, Corrah, Tumena, Daquiz, Venus, Dugan, Christopher, Elliot, Joshua, Foley, Fiona, Friday, Dawn, Gamit, May, Garner, David, Gokani, Karishma, John, Laurence, Joseph, Deepa, Khan, Nuzhath, Mamuyac, Cherifer, McGregor, Alastair, McSorley, John, Parris, Victoria, Rubinstein, Luciana, Rycroft, Julian, Salinas, Kelcy, Salinas, Jason, Sebatian, Jency, Smith, Melanie, Tejero Garcia, Marina, Ume, Uchenna, Vicentine, Margarete, Wallis, Gabriel, Sturdy, Ann, Whittington, Ashley, Jacobs, Nathan, Johnson, Leann, Bonington, Alec, Uriel, Alison, Ustianowski, Andrew, Dancso, Balazs, Hogan, Celia, van Halsema, Clare, Vilar, F Javier, Devine, Karen, Ajdukiewicz, Katherine, Rajendran, Rajesh, Ghosh, Samit, Riste, Michael, Machin, Nicholas, Babu, Chitra, Ahmad, Shazaad, Obeng, Dorcas, Dave, Farnaz, Conolley, Gavin, Thompson, Joseph, Tickell-Painter, Maya, Chakravorty, Prasun, Pringle, Rachel, Zafar, Mohammad R, Lawrence, Sarah, Sanchez-Gonzalez, Amada, Fernandez, Cristina, Goodwin, Lynsey, Carey, David, Howarth-Maddison, Molly, Moody, Samuel, Upton, Rebecca, Apthorp, Christina, Murray, Charlotte, Salthouse, Kirstie, Nadeem, Sabah, Ridley, Grant, White, Francesca, Brown, Andrew, Lawless, Michael, Mohamed, Mohamed, Mulligan, Robert, Belfield, Amy, Brolly, Jacob, Calderon, Maria, Cheveau, James, Cullinan, Milo, Garrad, Sophie, Griffiths, Will, Ireland, Aidan, Ireland, Peter, Milne, Charlotte, Nwajiugo, Paul, Quartey, John, Ghavami-Kia, Bijan, Duncan, Chris, Evans, Adam, Hunter, Ewan, Price, Ashley, Schmid, Matthias, Schwab, Uli, Taha, Yusri, Payne, Brendan, Elliott, Ivo A M, Crowe, Stewart, Woodrow, Charles J, Karageorgopoulos, Drosos E, Davis, Peter J, Lord, Emily, Bannister, Oliver J, Dagens, Andrew B, Harrison, Thomas, Cole, Joby, Tunbridge, Anne, Choudry, Saher, Telfer, Adam, Jhibril, Ihsan, Atta, Syed N, Stone, Ben, Evans, Cariad, Ankcorn, Mike, Akili, Suha, Yavuz, Mehmet, Goodall, Vicky, Farrow, Sam, Mountford, Georgina, Cusack, Tomas-Paul, Beard, Kate, Sutton, Julian, Clark, Tristan, Mason, Annette, Vickers, Mike, Macallan, Derek, Bicanic, Tihana, Houston, Angela, Pope, Cassie, Tan, NgeeKeong, Ward, Christopher, Jones, Imogen, Banerjee, Rishi, Cohen, Jonathan, Emonts-le Clercq, Marieke, Porter, David, Riordan, Andrew, Sinha, Ruchi, Whittaker, Elizabeth, Beynon, William, Heskin, Jospeh, Milligan, Iain, Payne, Lara, AI Payne, Brendan, Elliott, Ivo AM, and Beard, Katie

Published
2023
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36. The Relationship between Internationalisation, Creativity and Transformation: A Case Study of Higher Education in Hungary

Author

Smith, Melanie K. and Vass, Vilmos

Abstract

The main objective of this article is to explore the relationship between internationalisation, creativity and transformation in the context of higher education. It is argued in academic theory that the process of internationalisation in higher education has two pillars: transformational learning and creative development, and that creativity is an integral part of transformational learning. To explore this relationship further, the authors draw on primary research undertaken in the context of a higher education institution in Budapest, Hungary. A Delphi study with senior academic staff and a focus group with Hungarian and international students were included in the research. Questions were asked which aimed to determine whether creativity is indeed an integral part of transformational learning, and whether creativity and transformation are the most important elements of internationalisation. Staff and students recognise the creative and transformative potential of internationalisation, but they also identified several challenges. These include encouraging students to go beyond instrumental approaches to learning, providing staff with the relevant training and support, changing the culture of institutions and overcoming the lack of flexibility in existing national education structures. Overall, the research findings reinforced theoretical perspectives, which propose creative thinking, cooperative and communicative learning, project-based and problem-solving activities as some of the main tools in the process of transformational learning and prerequisites for internationalisation.

Published
2017

43. A new generation of sensors and monitoring tools to support climate-smart forestry practices

Author

Torresan, Chiara, Garzon, Marta Benito, O'Grady, Michael, Robson, Thomas Matthew, Picchi, Gianni, Panzacchi, Pietro, Tomelleri, Enrico, Smith, Melanie, Marshall, John, Wingate, Lisa, Tognetti, Roberto, Rustad, Lindsey E., and Kneeshaw, Dan

Subjects
Wireless sensor networks -- Usage, Forest management -- Methods, Earth sciences
Abstract

Climate-smart forestry (CSF) is an emerging branch of sustainable adaptive forest management aimed at enhancing the potential of forests to adapt to and mitigate climate change. It relies on much higher data requirements than traditional forestry. These data requirements can be met by new devices that support continuous, in situ monitoring of forest conditions in real time. We propose a comprehensive network of sensors, i.e., a wireless sensor network (WSN), that can be part of a worldwide network of interconnected uniquely addressable objects, an Internet of Things (IoT), which can make data available in near real time to multiple stakeholders, including scientists, foresters, and forest managers, and may partially motivate citizens to participate in big data collection. The use of in situ sources of monitoring data as ground-truthed training data for remotely sensed data can boost forest monitoring by increasing the spatial and temporal scales of the monitoring, leading to a better understanding of forest processes and potential threats. Here, some of the key developments and applications of these sensors are outlined, together with guidelines for data management. Examples are given of their deployment to detect early warning signals (EWS) of ecosystem regime shifts in terms of forest productivity, health, and biodiversity. Analysis of the strategic use of these tools highlights the opportunities for engaging citizens and forest managers in this new generation of forest monitoring. Key words: climate change, early warning signals, ecosystem regime shifts, wireless sensor network, Internet of Things, citizen science, green technologies. La foresterie intelligente face au climat est une branche emergente de la gestion forestiere adaptative et durable dont l'objectif est d'accroitre la capacite des forets de s'adapter au changement climatique et d'en attenuer les effets. Cela comporte beaucoup plus d'exigences en termes de donnees que la foresterie traditionnelle. Ces exigences en matiere de donnees peuvent etre satisfaites grace a de nouveaux appareils qui permettent de surveiller la foret in situ en continu et en temps reel. Nous proposons un reseau complet de capteurs, c.-a-d. un reseau de capteurs sans fil, qui peut faire partie d'un reseau mondial d'objets interconnectes individuellement adressables, un Internet des objets (IdO) qui peut rendre les donnees disponibles presque en temps reel a de nombreux interesses, incluant des scientifiques, des forestiers et des gestionnaires forestiers, et qui peut en partie motiver les citoyens a participer a une importante collecte de donnees. L'utilisation de sources in situ de donnees de suivi comme donnees d'entrainement validees sur le terrain pour des donnees de teledetection peut favoriser la surveillance des forets en augmentant les echelles spatiale et temporelle, permettant ainsi une meilleure comprehension des processus forestiers et des menaces potentielles. Certains des developpements et applications cles de ces capteurs sont presentes dans cet article avec des directives pour la gestion des donnees. Des exemples de leur deploiement pour detecter les signaux d'alerte rapide des changements de regime des ecosystemes en ce qui a trait a la productivite, l'etat de sante et la biodiversite de la foret sont presentes. L'analyse de l'utilisation strategique de ces outils met en evidence les occasions d'interesser les citoyens et les gestionnaires forestiers a cette nouvelle generation de suivi des forets. [Traduit par la Redaction] Mots-cles : changement climatique, signaux d'alerte rapide, changement de regime des ecosystemes, reseau de capteurs sans fil, Internet des objets, science participative, technologies vertes., 1. Introduction Forests have traditionally been managed as large blocks with uniform treatments. This approach simplifies management but may miss shifts in forest dynamics over time; however, new technology permits [...]

Published
2021
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48. Placenta-Specific Transcripts Containing Androgen Response Elements Are Altered In Silico by Male Growth Outcomes

Author

Meakin, Ashley S., primary, Smith, Melanie, additional, Morrison, Janna L., additional, Roberts, Claire T., additional, Lappas, Martha, additional, Ellery, Stacey J., additional, Holland, Olivia, additional, Perkins, Anthony, additional, McCracken, Sharon A., additional, Flenady, Vicki, additional, and Clifton, Vicki L., additional

Published
2024
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