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28. Randomized controlled trial of the effect of phytosterols-enriched low-fat milk on lipid profile in Chinese

Author

Daniel Ka-Chun Ho, Bernard M.Y. Cheung, Vincent Ka-Fai Cheng, Chor-Wing Sing, Yuk-Nam Ho, Ching-Lung Cheung, Grace Koon-Yee Lee, and Man Fung Tsoi

Subjects
Adult, Male, 0301 basic medicine, Hypercholesterolemia, Physiology, 030209 endocrinology & metabolism, Physical examination, Article, law.invention, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Asian People, Randomized controlled trial, law, Diabetes mellitus, Animals, Humans, Medicine, Young adult, Aged, Lactose intolerance, 030109 nutrition & dietetics, Multidisciplinary, High prevalence, medicine.diagnostic_test, business.industry, Anticholesteremic Agents, Phytosterols, Middle Aged, medicine.disease, Cholesterol, Milk, Blood pressure, Food, Fortified, Female, lipids (amino acids, peptides, and proteins), business, Lipid profile
Abstract

Phytosterols found naturally in plants are known to reduce cholesterol absorption in the gut. The traditional southern Chinese diet typically contains many vegetables and not much meat, and there is high prevalence of lactose intolerance in Chinese; we therefore aimed to test if phytosterols-enriched milk is effective in lowering serum LDL-cholesterol in Chinese. Two hundred and twenty-one participants (41 men and 180 women; age 24–79) without cholesterol-lowering drugs or diabetes mellitus were randomized to daily intake of phytosterols-enriched low-fat milk which contained 1.5 g phytosterols per day (N = 110) or a conventional low-fat milk (N = 111) for three weeks. Fasting bloods were taken before and at the end of the study for the measurement of lipid and glucose profile. Physical examination was also performed. Comparing treatment with control, treatment group had significant decrease in serum LDL-cholesterol level (9.5 ± 2.0%; p

Published
2017
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