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Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Resumo Fundamento: As doenças não comunicáveis são responsáveis por mortes prematuras e limitações. A aposentadoria por invalidez está associada a condições crônicas, especialmente a doenças cardiovasculares. A II Diretriz Brasileira de Cardiopatia Grave definiu critérios para enquadramento das doenças cardiovasculares. Poucos estudos abordam esse tema em instituições federais. Objetivos: Avaliar sobrevida e causas de óbito de servidores aposentados por invalidez na UFRJ, com ênfase no impacto da cardiopatia grave. Métodos: Estudo de coorte retrospectivo baseado nos registros de aposentadorias e óbitos ao longo de 15 anos. As aposentadorias foram divididas em três grupos: integral por cardiopatia grave, integral por outras doenças e proporcional. As causas de óbito foram obtidas a partir das certidões de óbito. Foram avaliadas taxa de mortalidade, sobrevida e a presença de diagnósticos concordantes entre a aposentadoria e o óbito. Foram utilizados testes qui-quadrado, log-rank, modelos de Cox e curvas de Kaplan-Meier. Significância estatística com intervalo de confiança de 95%, considerando p < 0,05. Resultados: Foram 630 aposentadorias, 368 (51,4%) no sexo feminino, com idade média de idade de 52,9 (DP=7,8) anos, e 169 (26,8%) óbitos. A mortalidade foi maior nos professores (37,0%; p=0,113), na faixa etária entre 65 e 70 anos (48,4%; p=0,004), no sexo masculino (34,0%; p=0,001), e nas aposentadorias integrais por cardiopatia grave (41,5%; p < 0,001). Diagnósticos concordantes entre aposentadoria e óbito foram mais frequentes em professores (74,1%; p=0,026) e nas aposentadorias integrais por cardiopatia grave (72,7%; p < 0,001). Conclusões: O diagnóstico de cardiopatia grave confere maior taxa de mortalidade e menor sobrevida aos aposentados por invalidez, e sua presença em maior frequência nos diagnósticos de aposentadoria e óbito ressalta sua importância neste contexto.

Introduction: Every year, five million people around the world experience an out-of-hospital cardiac arrest (OHCA) and less than 40 % receive any assistance before the arrival of the Emergency Medical Services (EMS). Ambulance operators (AO) take care of people experiencing an OHCA, stabilize and then transfer them. In Medellín, Colombia, there is a public AO and several private providers, but the information about an OHCA and the operational characteristics during the response to the event are limited. Objective: To estimate the incidence of OHCA and to explore the factors associated with survival after the event in Medellín city. Methods: Retrospective, population-based cohort study. All the medical records of patients experiencing an OHCA who were assessed and treated by ambulance operators, (AO) of the Emergency Medical Services (EMS) and private agencies in Medellin city were reviewed. Descriptive statistics were used for data analysis and the annual incidence of the event standardized for the general population was estimated. Potential survival-associated factors reported as OR with their corresponding 95% CI were explored. Results: A total of 1,447 patient records with OHCA between 2018 and 2019 were analyzed. The event incidence rate for the number of cases assessed was 28.1 (95 % CI 26.0-30.3) and 26.9 (95 % CI 24.9- 29.1) cases per 100,000 inhabitants/year for 2018 and 2019, respectively; the incidence rate of treated OHCA was 2.6 (95 % CI 2.0-3.3) and 3.2 (95 % CI 2.5-4.0) per 100,000 inhabitants/year, for 2018 and 2019. Survival on arrival at hospitals of treated cases was 14.2 % (95 % CI 5.5-22.8) and 15.5 % (95 % CI 7.4-23.5) for 2018 and 2019, respectively. Conclusions: This study portrays the operating and care characteristics of the population experiencing OHCA in Medellín city. The incidence rate of the event and the survival were lower than those reported in the literature. [ABSTRACT FROM AUTHOR]

Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introdução: A pandemia de covid-19 alterou a dinâmica de conservação dos enxertos e de realização dos transplantes de células progenitoras hematopoiéticas (TCPH) alogênicos, o que pode ter afetado a sobrevida dos pacientes. Objetivo: Analisar a sobrevida dos pacientes pós-TCPH imediato (100 dias pós-TCPH) segundo a exposição aos diferentes tipos de transplantes e fontes de enxerto, na pré-pandemia e na pandemia de covid-19. Método: Estudo de coorte retrospectivo de base hospitalar com 246 pacientes que realizaram TCPH em hospital de referência no município do Rio de Janeiro entre janeiro/2016 e dezembro/2021. Os métodos de log-rank e Kaplan-Meier foram utilizados para estimar as funções de sobrevida de pós-TCPH imediato. Resultados: A taxa de mortalidade foi ligeiramente superior na pandemia quando comparada à pré-pandemia (10,1% vs. 8,8%). O enxerto mais utilizado em todo o período estudado foi medula óssea (MO) com 85%. Porém, na pandemia, 50,5% das coletas alogênicas foram realizadas utilizando o sangue periférico mobilizado (SPM). Oito por cento dos enxertos criopreservados não foram infundidos. Não foram observadas diferenças na sobrevida entre pacientes que utilizaram SPM como fonte de enxerto em relação à MO. Conclusão: Os tipos de enxerto e as fontes de transplantes não influenciaram a sobrevida dos pacientes em ambos os períodos. A criopreservação se apresentou como uma ferramenta importante para superar os desafios logísticos ligados à pandemia de covid-19, porém, um percentual relevante de enxertos criopreservados não foi utilizado. Assim, é necessário que os centros transplantadores voltem a realizar TCPH com produtos frescos, reduzindo o percentual de inutilização dos enxertos.

Background: Hepatocellular carcinomas (HCC) represent approximately 50% of primary liver neoplasms and can be localized or distributed throughout the parenchyma. Lymphoma is the clonal proliferation of lymphocytes, with the multicentric form being the most common in dogs. Metronomic chemotherapy consists of the administration of low-dose antineoplastic agents at short, regular intervals. However, no effective treatment for nodular or disseminated HCC nor reports of metronomic chemotherapy in dogs with lymphoma exist. Thus, this study aimed to report the use of antineoplastic therapies in 2 dogs diagnosed with inoperable nodular HCC and multicentric lymphoma. Cases: The 1st patient was a 16-year-old bitch mixed breed weighing 7.4 kg that was treated at the Veterinary Hospital of the Federal University of Santa Maria (HVU-UFSM). Ultrasound examination revealed nodular structures measuring approximately 1 cm throughout the hepatic parenchyma, with the largest one measuring approximately 4.48 x 3.07 cm located in the left lateral lobe. An increased uterine volume was also observed. Exploratory celiotomy showed pyometra and hepatic nodules. Liver biopsy confirmed the diagnosis of HCC. Owing to the impossibility of surgical resection, the treatment of choice was metronomic chemotherapy with cyclophosphamide at 15 mg/mm2 every 48 h with follow-up imaging and blood tests. Nine months after diagnosis, a nodular area of approximately 1.5 x 1.3 cm was identified in the greater curvature of the stomach. The patient remained clinically stable, with stable neoplasm progression. However, at the age of 19 years, the bitch died 2 years and 5 months after the metronomic administration of cyclophosphamide, and the causa mortis was elderliness. The 2nd patient was a 10-year-old bitch Shih Tzu weighing 3.7 kg, referred for suspected lymphoma and also examined at the HVU-UFSM. The patient manifested with enlarged mandibular and popliteal lymph nodes and lymphocytic leukocytosis. A multicentric lymphoma was confirmed via fine-needle aspiration cytology (FNAC) and through clinical signs and blood tests. Chemotherapy treatment was initiated with the CHOP regimen, which included cyclophosphamide [200 mg/m2], vincristine [0.6 mg/m2], doxorubicin [25 mg/m2], and prednisone [5 mg/kg]. However, this regimen was not effective and changed to chlorambucil [3 mg/m2), VO, SID, for 4 days] and prednisone [1 mg/kg, VO, SID]. However, this protocol was not feasible due to the unavailability of the drug on the market; therefore, metronomic chemotherapy was initiated. The bitch received cyclophosphamide 15 mg/m2 every 48 h, showing clinical improvement in the lymphocytic leukocytosis. Chronic anemia, weight loss, leukemia, and chronic kidney disease occurred as complications and were treated accordingly. The bitch lived for 3 years and 6 months after the diagnosis and eventually died due to years of treatment and worsening general condition due to the acquired complications. Discussion: Veterinary Medicine is faced with several challenges in designing effective metronomic chemotherapy regimens, including the selection of appropriate drugs and the establishment of effective doses. Both patients in this report received cyclophosphamide [15 mg/m2, every 48 h]. In human medicine, metronomic chemotherapy is considered a safe and potentially useful treatment, which was observed in the reported patients since it presented few side effects and an increased survival period of 880 days in the patient with HCC and 1,275 days in the patient with multicentric lymphoma. This regimen can be considered for inoperable tumors and in cases of refractory to conventional regimens. [ABSTRACT FROM AUTHOR]

Background and objectives: The rates of (interval) stomach cancer (SC) or postendoscopy (PECRC) or postcolonoscopy (PCCRC) colorectal cancer (CRC) have been little studied in our setting. Data from overseas studies reported PECRC and PCCRC rates of 7-26%. We aim to determine and compare local PECRC and PCCRC rates and characteristics. Patients and methods: With data from three quaternary-care cancer centers, we ambispectively identified patients diagnosed with SC and CRC between 2012 and 2021, in whom a history of endoscopies or colonoscopies in the previous three years was investigated. Cancers diagnosed between 6 and 36 months after an endoscopic study reported as normal were defined as interval cancers. This study compares the clinical, endoscopic, and survival characteristics of both PECRC and PCCRC cohorts. Results: Of 828 patients diagnosed with SC, 66 had PECRC (rate: 7.3%), while in 919 patients with CRC, 68 had PCCRC (rate: 6.9%). There were no significant differences in age or sex, although males predominated (2:1) in the PECRC (0.09). The finding of premalignant lesions was similar in both groups (p = 0.260). The anatomical location was shown to be more proximal (right colon) in the PCCRC than in the PECRC (cardia/fundus) (p = 0.002). Gastric neoplasms were more poorly differentiated (58%) than colon neoplasms (26%) (p = 0.001). There were no differences in early cancers, but tumor status was more advanced in PECRC (p < 0.01). The Kaplan-Meier showed a worse survival for PCCRC than for detected CRC, with no differences in SC and PECRC, suggesting poor survival. Conclusions: The rate of interval cancers is 7.3% and 6.9%, and differences were found between PECRC and PCCRC, proximal locations of the lesions, degree of differentiation, tumor status, and poor survival for the PCCRC. Establishing measures to achieve the World Endoscopy Organization's goal of <5% is necessary. [ABSTRACT FROM AUTHOR]

Copyright of Actualización en Nutrición is the property of Sociedad Argentina de Nutricion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Colombian Journal of Nephrology / Revista Colombiana de Nefrología is the property of Colombian Association of Nephrology & Hypertension and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introdução: A síndrome respiratória aguda grave ocasionada pela doença do coronavírus (COVID-19), tem rápida disseminação e comportamento instável. Embora a maioria das manifestações clínicas da COVID-19 sejam assintomáticas ou leves, existem formas graves que exigem internação em Unidade de Terapia Intensiva. Objetivo: analisar os fatores associados a sobrevida e mortalidade de pessoas com COVID-19 internadas em unidade de terapia intensiva. Método: Trata-se de um estudo de coorte retrospectivo no período de março a agosto de 2020, de pessoas com COVID-19 internadas na unidade de terapia intensiva de um hospital público referência no tratamento de doenças infectocontagiosas no Estado do Ceará, Brasil. Determinou-se a probabilidade de sobrevida com Kaplan Meier, com cálculos de sobrevida pelo software R versão 3.2 e comparação entre curvas de sobrevida. Considerou-se o nível de significância p=0,05. Resultados: Das 92 pessoas com COVID-19, 66,3% eram homens, obesos (23,38%), com doença cardiovascular (19,48%) e HIV (19,48%). Foi observada diferença estatística significativa (p=0,03) com a hipertensão. O tempo médio de sobrevivência foi de 33,93. A mortalidade por COVID-19 foi 69,6%. Conclusão: A chance de sobrevivência foi maior nas mulheres. A idade avançada, sexo masculino, obesidade e hipertensão foram associados a maior risco de morte. Os resultados da presente pesquisa podem ajudar gestores e profissionais da saúde a identificar grupos de alto risco que devem receber intervenções e cuidados de suporte invasivos.

Introducción: El cáncer de laringe es el tumor maligno de mayor prevalencia en la Otorrinolaringología. La topografía glótica es la más frecuente en Uruguay y suele detectarse en estadios tempranos dada la manifestación precoz y sostenida de disfonía. El objetivo de este estudio es describir la sobrevida libre de enfermedad (SLE) y la sobrevida global (SG) de los pacientes con cáncer de laringe glótico en estadio T1N0M0 en 4 instituciones de Montevideo. Metodología: Se analizó de forma retrospectiva la SG y SLE de 55 pacientes diagnosticados con cáncer de glotis T1 entre los años 2009 y 2019. Para el cálculo de la sobrevida se utilizó el método de Kaplan-Meier. Se estudió además el efecto de variables pronósticas de interés sobre la SG mediante análisis univariado y multivariado. Resultados: En la muestra analizada la SG de los pacientes con cáncer glótico T1N0M0 fue como media de 7.706 años (IC 95% 6.63 - 8.78). A los 5 años, la SG fue de 77.5% (± 7%) y de 62% (± 9.8%) a los 10 años. La SLE para todos los pacientes correspondió al 74.6% (± 7.5%) y 63.1% (± 9.8%), a 5 y 10 años respectivamente. No se alcanzaron las medianas de SG ni de SLE para los grupos. Conclusiones: Los valores de SG y SLE medios obtenidos en nuestro medio son comparables a los valores reportados en la bibliografía internacional. No se alcanzó la mediana de SG ni de SLE, por lo que se puede afirmar que ésta enfermedad tiene, cuandose realiza el tratamiento adecuado, un buen pronóstico vital a los 10 años. Se requiere un seguimiento más largo para determinar las medianas de SG y SLE de los grupos en estudio.

Introdução: O melanoma acral (MA) está associado à alta mortalidade e à baixa sobrevida, e seu prognóstico é pior em comparação com os outros subtipos de melanoma. Objetivo: Analisar o poder preditivo de aspectos demográficos e clinicopatológicos em pacientes com MA. Método: Estudo retrospectivo com pacientes diagnosticados com MA entre janeiro de 2001 e dezembro de 2015. Foram coletadas características demográficas e clinicopatológicas. O desfecho foi a sobrevida global (SG) em cinco anos. Foram utilizados curvas de Kaplan-Meier, teste de log-rank e análise de regressão de Cox. Resultados: Foram identificados 394 pacientes com MA. A taxa de sobrevida em cinco anos para pacientes com MA foi de 45,6%. Os fatores preditivos da SG incluíram espessura de Breslow [hazard ratio (HR): 1,02, intervalo de confiança (IC) de 95%: 1,01-1,03], ulceração (HR: 4,06, IC 95%: 2,18-7,57) e invasão linfovascular (ILV) (HR: 2,12, IC 95%: 1,12-4,00). Conclusão: Tais achados destacam o prognóstico desfavorável do MA e o poder preditivo da espessura de Breslow, ulceração e ILV.

Introducción: En Argentina el cáncer de endometrio es el segundo tumor ginecológico más frecuente, representando el 6% de todos los cánceres en mujeres. El objetivo de este trabajo es evaluar los resultados oncológicos y perioperatorios, en pacientes con cáncer de endometrio de alto riesgo (CEAR) limitados al útero tratadas en el Hospital Italiano de Buenos Aires entre enero 2010-2018. Métodos: Estudio de cohorte retrospectivo que evaluó los resultados perioperatorios, la supervivencia libre de enfermedad a los 2, 4 años en pacientes con CEAR. Resultados: 74 pacientes cumplieron con los criterios de inclusión. Los tumores serosos fueron los más frecuente n=38 (51%), mientras que los desdiferenciados, los de menor frecuencia, n=2 (3%). 56 (76%) pacientes recibieron al menos un tratamiento adyuvante. El tratamiento sistémico fue implementado en 28 pacientes (38%), mientras que 24 (33%) recibieron una combinación de quimioterapia y radioterapia. La mediana de seguimiento fue de 2,9 años. La supervivencia libre de enfermedad, en pacientes con estadio IA a los 2 y 4 años fue de 71% (IC 95% 55-82) y 63 % (IC 46 -76) respectivamente, mientras que aquellas que presentaban un estadio IB fue de 53 (IC 95% 33-70) y 38 (IC 95% 19-58). En cuanto a la vía quirúrgica de abordaje, no se encontraron diferencias significativas en la supervivencia libre de enfermedad ni en las complicaciones perioperatorias. Conclusión: Sólo el estadio FIGO mostró un aumento en la probabilidad de muerte o recaída independientemente del tipo de tratamiento adyuvante realizado y de la vía de abordaje seleccionada.

Introduction: Pancreatic cancer (PC) remains one of the most lethal malignancies, despite developments in surgical and non-surgical therapies. Significant improvements in long-term survival have not been achieved. Only radical surgical resection has obtained a moderate extension in survival. We aim to identify factors associated with longer survival in patients with PC treated by pancreatoduodenectomy (PD). Material and Method: We designed a case-control study of patients with PC treated by PD in our center between 2002-2015. We compare patients who survived ≥ 3 years (case) with those not achieving it (control). Bio-demographic, clinical, histopathological, morbidity and mortality data were compared between cases and controls using logistic regression. Results: Seventy patients were analyzed; mean age 62 ± 11 years; 40 (57%) women. Morbidity was found in 26 patients (37.1%); Clavien-Dindo ≥ IIIa in 8 (11.4%). The median (range) of hospitalization days was 12 (7-84). The actuarial 1, 3, and 5 years survival was 77%, 32%, and 22%, respectively, for the entire series. Twenty-one cases (30%), and 49 controls (70%) were identified. In the univariate analysis, R0 resection, negative regional lymph nodes, the absence of perineural infiltration, the earliest stages (IA, IB, and IIA) and the absence of diabetes mellitus (DM) at time of diagnosis were variables associated with survival > 3 years (p < 0.05). Hypoalbuminemia (< 3 mg / dL), CA 19-9 (> 100 U / mL), and neo/adjuvant treatments, did not significantly show differences in survival. In the multivariate analysis, no DM at diagnosis (adjusted OR: 12; 95% CI 1.7 - 84.3), no perineural infiltration (adjusted OR: 7; 95% CI 1.3 - 36.3) and early stages IA, IB, and IIA (adjusted OR: 10.3; 95% CI 2.1 - 49.1) were identified as independent factors associated with survival > 3 years. Conclusion: Nondiabetic patients with early stages PC without perineural infiltration, resected R0 by PD can achieve survival over 3 years. [ABSTRACT FROM AUTHOR]

Copyright of Revista de Gastroenterología del Perú is the property of Sociedad de Gastroenterologia del Peru and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Chilena de Urologia is the property of Sociedad Chilena de Urologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Heart rehabilitation in patients with valvular prosthesis is essential to increase their survival and incorporate them optimally to the society. Objective: To characterize patients with mechanical valvular prosthesis and cardiovascular rehabilitation. Methods: An observational, descriptive, serial cases study of 70 patients with mechanical valvular prosthesis was carried out, who were admitted to the program of cardiovascular rehabilitation of Vladimir Ilich Lenin University General Hospital in Holguín province, from March, 2019 to November, 2022. Results: There was a prevalence of 55 to 64 years patients (38.6%), with prosthesis in mitral position, without complications. In the rehabilitated patients a reduction of the mean in hypercholesterolemia was observed (from 250 to 175 mg/dL) and an increase of the functional capacity due to the duration of exercise, as well as of the consumed metabolic units. There was an increase from 52.4 to 58.2% in the mean of the left ventricular function after the rehabilitative therapy. Only 2 affected patients needed rehospitalization and to incorporate more medication to their basal treatment and 50 returned to their working activities. The result was satisfactory in 97.1% of the series members. Conclusions: This therapy was beneficial, because there was an increase of the functional capacity of patients and complications were not very common. The coronary risk factors were controlled; there was a reduction of rehospitalization and an increase of working reincorporation. [ABSTRACT FROM AUTHOR]

Introduction: Heart rehabilitation in patients with valvular prosthesis is essential to increase their survival and incorporate them optimally to the society. Objective: To characterize patients with mechanical valvular prosthesis and cardiovascular rehabilitation. Methods: An observational, descriptive, serial cases study of 70 patients with mechanical valvular prosthesis was carried out, who were admitted to the program of cardiovascular rehabilitation of Vladimir Ilich Lenin University General Hospital in Holguín province, from March, 2019 to November, 2022. Results: There was a prevalence of 55 to 64 years patients (38.6%), with prosthesis in mitral position, without complications. In the rehabilitated patients a reduction of the mean in hypercholesterolemia was observed (from 250 to 175 mg/dL) and an increase of the functional capacity due to the duration of exercise, as well as of the consumed metabolic units. There was an increase from 52.4 to 58.2% in the mean of the left ventricular function after the rehabilitative therapy. Only 2 affected patients needed rehospitalization and to incorporate more medication to their basal treatment and 50 returned to their working activities. The result was satisfactory in 97.1% of the series members. Conclusions: This therapy was beneficial, because there was an increase of the functional capacity of patients and complications were not very common. The coronary risk factors were controlled; there was a reduction of rehospitalization and an increase of working reincorporation.

Resumo Fundamento A Doença de Chagas (DC) é uma causa importante de transplante cardíaco (TC). O principal obstáculo é a reativação da DC (RDC), normalmente associada a altas doses de imunossupressores. Estudos anteriores sugeriram uma associação do micofenolato de mofetila com aumento na RDC. No entanto, preditores de mortalidade são desconhecidos. Objetivos Identificar os fatores de risco de mortalidade em pacientes com DC após o TC e o impacto do regime antiproliferativo sobre a sobrevida. Métodos Estudo retrospectivo com pacientes chagásicos submetidos ao TC entre janeiro de 2004 e setembro de 2020, em protocolo de imunossupressão que priorizava o uso de azatioprina e sua mudança para micofenolato de mofetila em caso de rejeição. Realizamos regressão univariada para identificar preditores de mortalidade e comparamos sobrevida, rejeição, e evidência RDC entre os pacientes que usavam azatioprina, micofenolato de mofetila, e aqueles que mudaram de azatioprina para micofenolato (grupo “Mudança”) após a alta. Um valor de p

As the world’s population lives longer and longer and has more cardiovascular risk factors, there is a greater prevalence of cardiovascular disease, including heart failure. Advances in medical knowledge, specifically in molecular, physiological and clinical fields, provide new and improved pharmacological treatments, cardiac devices and surgical procedures today which have optimized this condition’s prognosis. The available surgical procedures for treating heart disease include heart transplantation, which is useful for patients with advanced disease or disease which is refractory to the ordered and implemented interventions. The world’s first heart transplant was performed in 1967, and Colombia’s first in 1985. As of 2021, more than 1,400 heart transplants had been performed in this country. This procedure seeks to improve the quality of life and survival of patients who need it. The purpose of this article is to compile the historical events surrounding this surgical procedure around the world and in Colombia. [ABSTRACT FROM AUTHOR]

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: One of the mainstays in the treatment of locally advanced rectal cancer is neoadjuvant chemoradiotherapy. Neoadjuvant therapy have demonstrated to decrease local recurrence, also generating tumor downstaging, even leading to a pathological complete response (PCR), the latter related to better overall survival (OS) and disease-free survival (SLE). Aim: To report the anatomo-pathological results of treatment with chemoradiotherapy in rectal cancer, analyzing the relationship with OS and SLE. Material and Method: Prospective cohort study. A database of colorectal surgeries from the Clinical Hospital of the University of Chile between the years 2004-2019, including patients with locally advanced low and middle rectal cancer, who received neoadjuvant and later surgery. Survival analysis was made with the Kaplan-Meier method and the Log-rank test for comparison. A value of p < 0.05 was considered statistically significant. Results: 411 patients underwent surgery for rectal cancer, 143 patients received neoadjuvant therapy, 19% registered PCR. The OS of the group with PCR was 94% (95% CI; 59.79-79.41%) while that of the group without PCR was 71% (95% CI; 66.64-99.20%) (p = 0.018), the SLE in those patients with PCR reached 100%, while in those without PCR it was 74% (95% CI; 64.08-81.28) (p = 0.008). Conclusions: Patients with PCR have better long-term results than those without PCR. PCR could indicate a favorable biological tumor profile, with less tendency to recurrence and improved survival. [ABSTRACT FROM AUTHOR]

Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Em estudos epidemiológicos a expressão sobrevida tem sentido bem amplo. Para câncer, por exemplo, sobrevida após o diagnóstico pode ser a quantidade de anos (ou meses, ou dias) que um paciente permanece vivo após um diagnóstico (clínico ou radiológico, ou por biópsia, etc.) de câncer. Mas também se poderia definir sobrevida após alta clínica o tempo para um paciente ter uma recidiva.

Oitenta e seis pacientes com câncer de mama e linfonodos axilares positivos foram submetidos à mastectomia radical modificada seguida de quimioterapia com ciclo fosfamida e fluorouracil na dose de 600mg/m2 e methotrexate 40mg/m2, endovenosos, repetidos a cada 21 dias (CMFmod), durante seis meses (Oito ciclos). O tratamento adjuvante era iniciado no prazo máximo de 30 dias da cirurgia. O resultado do CMFmod foi comparado com grupo-controle histórico da própria instituição, constituída por 186 doentes tratadas pela mastectomia radical à Halsted e radioterapia. Decorridos 48 meses de seguimento, 72 (85%) estavam vivas e 42 (49/c) livres de doença no grupo do CMFmod e no grupo-controle 132 (7 1%) estavam vivas com 94 (51%) sem evidência de doença (p = 0,70 e p

Foi analisada a sobrevida de 40 pacientes (39 do sexo feminino e um do masculino) portadores de câncer primário da vesícula biliar. A sobrevida dependeu do nível de invasão da parede vesicular (Classificação de Nevin e colaboradores), a qual variou de seis dias a três anos, sete meses e 22 dias, cuja sobrevida média foi de 5,5 meses. A sobrevida global (método atuarial de Kaplan & Meier) foi de 18% (seis meses) e 15% (um ano). Enfatiza a necessidade de obtenção de um diagnóstico mais precoce, utilizando os métodos modernos de diagnóstico por imagem, pois, clinicamente, o diagnóstico precoce é impossível. Compara os seus resultados com os relatados na literatura médica.

Resumo Objetivo Analisar os preditores de mortalidade e o tempo médio de sobrevivência dos pacientes internados nas unidades de terapias intensivas. Métodos Coorte prospectiva, realizada no período de agosto de 2018 a julho de 2019, em quatro Unidades de Terapia Intensiva (UTI) de adultos, da rede pública e privada do Estado de Sergipe. Foram incluídos todos os pacientes adultos, desde que possuíssem o tempo de permanência mínima de 24 horas na unidade. O desfecho primário foi o óbito. Os desfechos secundários foram: diálise, lesão por pressão, lesão renal aguda, necessidade de ventilação mecânica invasiva por mais de 48 horas, infecção e o tempo de internação. Resultados Dos 432 pacientes, houve predomínio de óbito em pacientes do sexo masculino, com idade mais avançada e procedentes da unidade de emergência. A presença de insuficiência cardíaca, valores de creatinina >1,5 mg/dL na admissão, diabetes mellitus, doença hepática e tabagismo também tiveram associação com o desfecho óbito. Quanto aos demais preditores, destacaram-se o maior tempo de internação; maiores escores do Sequential Organ Failure Assessment (SOFA), Simplified Acute Phisiology (SAPS 3) e Nursing Activies Score (NAS), além do uso de noradrenalina. O uso do fentanil foi associado ao aumento do tempo de sobrevida e o tempo médio de sobrevivência geral foi 28 dias. Conclusão Os preditores de mortalidade dos pacientes internados em UTI de Sergipe foram o maior tempo de internação; os maiores escores de SOFA, SAPS-3 e NAS; creatinina >1,5mg/dl na admissão; uso de drogas vasopressoras e a necessidade de diálise.

Background: kidney transplantation is a routine therapy in current medical practice. Survival of the renal graft varies depending on clinical and epidemiological factors, related to the donor, the organ preservation conditions and the recipient. Objective: to determine survival and predictors of renal graft failure in patients treated in the Nephrology department of "Manuel Ascunce Domenech" Provincial Surgical-Clinical and Teaching Hospital, Camagüey, from 2000 to 2019. Methods: a prospective longitudinal survival study was performed. The study population consisted of 260 patients transplanted with a cadaveric donor, who were followed until the loss of the graft or the end of the study. Graft survival was analyzed using the Kaplan-Meier method, survival curves were compared with the log-rank test, and Cox regression was used to determine the predictive variables of graft survival time. Results: overall survival per year of renal grafts was 68.2 %; graft dysfunction was the complication with the highest incidence (25 %). Predictors of loss of renal graft function included: non-use of antilymphocyte antibodies, acute rejection, acute tubular necrosis, urinary tract infection and initial delayed function. Conclusions: survival was determined and predictors of renal graft failure were identified in the study patients.

RESUMO Objetivo: Analisar a sobrevida específica em cinco anos do câncer colorretal diagnosticado entre 2008 e 2013, segundo sexo e faixa etária, de residentes na Grande Cuiabá, Mato Grosso. Métodos: Estudo de coorte retrospectiva. A sobrevida específica pelo câncer colorretal foi considerada como o tempo entre o diagnóstico da doença até o óbito por câncer colorretal, em meses. Utilizaram-se dados do Registro de Câncer de Base Populacional e do Sistema de Informações sobre Mortalidade. Para estimar a probabilidade de sobrevida por sexo e faixa etária, utilizou-se o estimador de Kaplan-Meier, e, para estimar o efeito da faixa etária na sobrevida dos participantes, foi ajustado modelo de Cox estratificado por sexo. Resultados: De 2008 a 2013, registraram-se 683 casos novos e 193 óbitos por câncer colorretal. O tempo mediano entre o diagnóstico e a morte por câncer colorretal foi de 44,8 meses (IC95% 42,4–47,3) para as mulheres e 46,1 meses (IC95% 43,4–48,6) para os homens e a probabilidade de sobrevida em cinco anos de 83,5% (IC95% 79,9–87,2%) e 89,6% (IC95% 86,4–93,0%), respectivamente. Os homens com 70-79 anos (HR=2,97; IC95% 1,11–3,87) e com 80 anos ou mais (HR=3,09; IC95% 1,31–7,27) apresentaram maior risco de mortalidade e sem diferença para as mulheres. Conclusão: O sexo feminino apresentou menor tempo entre o diagnóstico e o óbito pela doença, assim como menor probabilidade de sobrevida. Em contrapartida, foram os homens que apresentaram maior risco de mortalidade a partir dos 70 anos.

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Copyright of Revista Gaucha de Enfermagem is the property of Revista Gaucha de Enfermagem and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Arquivos de Neuro-Psiquiatria is the property of Thieme Medical Publishing Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objetivo: Identificar factores asociados a la mortalidad en pacientes con cáncer de próstata. Métodos: Se realizó un diseño epidemiológico de estudio observacional analítico de casos y controles anidado en una cohorte en pacientes con cáncer de próstata. Los casos se definieron como pacientes fallecidos y los controles fueron los pacientes que al final del estudio seguían vivos. Resultados: La mortalidad observada en pacientes con cáncer de próstata fue del 41.8%. Los factores asociados de morir por cáncer de próstata fueron pacientes con edad ≥60 años, viviendo en zona rural, sin pareja, con sobrepeso, y están en etapas avanzadas de la enfermedad incluyendo la metástasis. La sobrevida estimada en esta población fue del 71% (IC95%: 67.5%-74.6%) durante el periodo de estudio. Conclusiones: La disminución de la sobrevida según años de seguimiento coincide con la evidencia hallada en estudios en Colombia.

Resumo Os limites da fração de ejeção do ventrículo esquerdo (FEVE) para a insuficiência cardíaca (IC) com FEVE levemente reduzida (ICFElr) têm sido questionados, já que evidências demonstram que alguns medicamentos utilizados para IC com FEVE

Objetivo. Evaluar las características epidemiológicas, clínicas, quirúrgicas, patológicas y desenlaces en el seguimiento de los pacientes receptores de trasplante cardiaco en el Instituto Nacional Cardiovascular durante 2010-2020. Materiales y métodos. Estudio retrospectivo descriptivo de pacientes sometidos a trasplante cardiaco en un centro de referencia nacional, se describen las características clínicas, quirúrgicas, de laboratorio, de patología y la supervivencia de los pacientes hasta los 10 años de seguimiento. Resultados. Ochenta y seis pacientes fueron trasplantados en 10 años, la mediana de edad fue de 41 años (RIQ 28-56), con predominancia de varones (66,3%). Las tres primeras causas de indicación de trasplante cardiaco fueron: cardiomiopatía dilatada (48,9%), cardiopatía isquémica (17,4%) y miocarditis (6,9%). El tiempo de isquemia total fue de 160 min (RIQ 129,7-233,5). La sobrevida al año, cinco y diez años fue de 84,8%, 73,6% y 65,7%, respectivamente. La principal causa de muerte fue la infecciosa (39,1%) y de origen desconocido (26%). Conclusiones. La principal etiología de la insuficiencia cardiaca en el receptor de trasplante cardiaco en el Perú, en los últimos años, fue la cardiomiopatía dilatada no isquémica. Se observa que la tasa de sobrevida fue similar a la de registros internacionales; sin embargo, la tasa de mortalidad de causa infecciosa y muerte de origen desconocido es alta, lo cual plantea un desafío en el manejo de los pacientes postrasplante.

Objective. To estimate the incidence, mortality and five-year survival of endometrial carcinoma in Manizales for the period 2003-2017. Materials and methods. Observational, retrospective, population-based study, descriptive in scope. Incidence and mortality rates were adjusted by the direct method using the Segi world population as reference. Passive and active follow-up of the cases was carried out until completing 60 months or until the follow-up closing date. Survival was estimated using Kaplan-Meier functions and Cox models. Results. 210 incident cases were observed in a population of 214.928 women. The average age at diagnosis was 61 years. The most frequent histological type was endometrioid, well differentiated. Most of the patients were affiliated to the contributory health insurance scheme and belonged to the middle socioeconomic level. The age-adjusted incidence rate was 5.7 new cases per 100,000 woman-years. Seventy-five deaths were identified, with greater mortality between 65-69 and 75-79 age groups. Overall survival was 95.1% at 12 months and 83.8% at 60 months. Statistically significant differences were found in survival in favor of epithelial histology, early stages at the time of diagnosis, and age at diagnosis less than 60 years. Conclusions: Manizales follows the global pattern of rise in the age-adjusted incidence rate. Mortality is like that reported in other countries in the region. In Manizales, endometrial cancer survival was higher in patients with early diagnosis, less than 60 years of age, and with endometrioid histology.

Background: Laryngeal carcinoma is the 22nd most common cause of cancer in men worldwide and the second most common head and neck malignancy. The care of these patients is multidisciplinary. Factors such as tumor stage and initiation of treatment 60 days after diagnosis have been associated with worse survival. Objective: To know the overall time of care in laryngeal cancer and its impact on the outcome of patients in a tertiary health center. Material and methods: In July 2020, a retrospective study was carried out of 173 patients with laryngeal cancer diagnosed in the Department of Otorhinolaryngology from January 2014 to December 2018. Odds ratio and Fisher's exact test were calculated with a p value of 0.05. Results: 2 out of 77 patients started treatment at the recommended time. The total attention time (TAT) was 246 ± 159 days. 56% of the patients were still alive, 43% diseasefree and 10% with progression. Control of the disease was achieved in 69% of early tumors and only 26% in advanced ones. Conclusions: The overall time of care impacts on the health status, affecting survival and control of disease. The stage of the tumor at the time of diagnosis is a decisive prognosis factor. Strategies towards multidisciplinary management and early detection in primary care should be created. [ABSTRACT FROM AUTHOR]

Copyright of INSPILIP. Revista Ecuatoriana de Ciencia, Tecnología e Innovacion en Salud Pública is the property of Instituto Nacional de Investigacion en Salud Publica (INSPI) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Uma das possiblidades de sobrevida da personagem, na perspectiva de uma teoria da figuração, projetada pelo crítico Carlos Reis, é a sua incorporação a uma narrativa subsequente àquela em que foi originalmente construída. A mulher do médico, por exemplo, é concebida na célebre obra Ensaio sobre a cegueira, de José Saramago, e refigurada como personagem secundária em Ensaio sobre a lucidez, do mesmo autor. O presente artigo analisa os elementos constitutivos dessa personagem, nas duas obras, a partir do entrecruzamento das vozes do narrador e da própria personagem, como proposto nas relações dialógicas descritas por Bakhtin. À luz das concepções de Brian Richardson acerca da personagem e de sua potencial transtextualidade, estima-se identificar aspectos que se mantenham fiéis à mulher do médico em ambas as obras e interrogar os que se diferem nesse processo de refiguração ou de reconstrução de uma mesma entidade, contribuindo, assim, para a revitalização dos estudos da personagem.

Foram comparados dois grupos de pacientes portadores de carcinoma broncogênico com derrame pleural: num grupo com 21 pacientes realizou-se pleurodese com tetraciclina ou mitomicina, no outro grupo com 66 paciente não se realizou a pleurodese. Foram escolhidos, para realizar pleurodese, aqueles que apresentas-sem reacumulação rápida de líquido pleural e que tivessem a perspectiva de sobrevida de meses. Para que não houvesse uma tendenciosidade de colocar a população com melhor prognóstico num dos grupos, avaliou-se os índices de Karnofsky inicial para os 2 grupos com o teste de Mann-Whitney que os mostrou serem praticamente iguais. Realizou-se a curva de estimativa da probabilidade de sobrevida de Kaplan-Meier e o teste do produto do momento de Cox-Mantel para a comparação da sobrevida dos dois grupos. A sobrevida foi maior para os pacientes que realizaram a pleurodese e foi estatisticamente significante (p 0,01602).

Introdução: Pacientes em acute on chronic liver failure (ACLF) apresentam características distintas daquelas apresentadas por pacientes hepatopatas não ACLF. O grau de ACLF impacta no desfecho com ou sem o transplante, havendo divergências na literatura principalmente no que tange ao prognóstico pós-transplante. Objetivos: Revisar os diferentes aspectos dos pacientes em ACLF, abrangendo os conceitos da síndrome adotados por diversas instituições, o tratamento das complicações, e descrever o conhecimento acerca dos desfechos com ou sem transplante dos portadores da síndrome reportados na literatura. Métodos: Foram incluídos 22 artigos encontrados na busca de bases de dados PubMed, Medline e Biblioteca Eletrônica Científica Online (SciELO) com os descritores “ACLF definitions” e “Liver transplantation ACLF”. Os conceitos e dados apontados nos textos selecionados foram comparados e utilizados como base para redigir este artigo. Resultados: Existem algumas diferenças na definição da síndrome, variando especialmente entre os países do Ocidente e os do Oriente. Pacientes aguardando transplante hepático em ACLF apresentam características distintas daquelas apresentadas por pacientes não ACLF. O grau de ACLF também impacta no desfecho com ou sem o transplante, havendo divergências na literatura principalmente no que tange ao prognóstico pós-transplante dos pacientes em ACLF 3, com tendência cada vez maior na indicação do transplante mesmo para esses pacientes. Conclusões: Os desfechos variam entre pacientes em ACLF de acordo com o grau da doença. O transplante hepático tem sido mais frequentemente indicado em ACLF 3, tendo o tempo de espera impactado os resultados. São necessários mais estudos para definir quais subgrupos de pacientes se beneficiam mais do transplante hepático.

Foram estudados 39 casos de pacientes menores de 21 anos portadores de rabdomiossarcoma matriculados no Hospital de Câncer no período entre 1988 a 1993. O estudo baseia-se no protocolo IRS III (Intergroup Rhabdomyosarcoma Study III) quanto aos regimes terapêuticos utilizados, a distribuição por sítios primários, histologia, grupos e estádios. As curvas de sobrevida foram determinadas para dois grupos e momentos distintos: O primeiro grupo incluiu todos os pacientes, o momento zero foi considerado como o do início do tratamento e o evento final, a data da última observação. Para o segundo grupo foi considerado como momento zero o término do tratamento para aqueles pacientes que se encontravam em remissão completa, e como evento final o momento da recidiva ou da última observação para aqueles que ainda permaneciam sem evidências de doença. Foi utilizado o Método de Kaplan-Meier.

A grande dificuldade, na literatura, para a avaliação dos diferentes métodos utilizados no tratamento paliativo dos tumores irressecáveis do hilo hepático, foi a inexistência de um parâmetro que tornasse uniforme a linguagem dos seus resultados. Este estudo tem por finalidade analisar os resultados da anastomose colangioentérica intraparenquimatosa (ACEI) no dueto do seguimento III, realizada em 17 pacientes consecutivos, portadores de obstrução maligna do hilo hepático. Para tanto, foi avaliado, dentre outras variáveis, um índice de qualidade de vida, denominado índice de Conforto, que permite a comparação numérica dos resultados. Houve regressão importante da icterícia em 88,2% dos casos, e redução estatisticamente significativa dos niveis sericos das bilirrubinas no pos operatorio (p

Introduction: Introduction: palliative care has been linked to the management of patients without a curative option. The detection of malnutrition allows establishing nutritional intervention strategies to make an adequate use of resources and contribute to support measures. Objective: to describe changes in nutritional status and their impact on survival in patients with cancer disease under palliative care. Methods: descriptive observational study of a retrospective cohort. The patients had stage IV cancer disease, Karnofsky index ≤70 and a survival prognosis <6 months. A complete nutritional assessment was carried out and they were followed for one year. The nutritional status and its characteristics, the presence of cachexia and the median survival at one year were described. Results: of 256 patients at the beginning of the follow-up, 60,9 % had some degree of malnutrition, which increased to 71,9 % at the end of the follow-up. There was an increase in patients with a thin body mass index (BMI) (+7.6%, p = 0.04) and a decrease in patients with excess weight (overweight -3.6%, p = 0, 24; and obesity -2.6%, p = 0.17). Overall survival at 1 year was 60 % (95% CI: 53-65). Conclusion: malnutrition was frequent in patients under palliative care (60,9 %) and increased throughout the follow-up. Differences were observed between the complete nutritional diagnosis and BMI, which can lead to a misclassification of the diagnosis and a decrease in the effectiveness of cancer treatment. [ABSTRACT FROM AUTHOR]

Objective: To describe the characteristics of adult patients with tuberculosis (TB) and diabetes mellitus (DM) in Peru, and to explore the association of DM and mortality in people with TB. Materials and methods: We carried out a secondary analysis of the database of the Management Information System of Tuberculosis of the Tuberculosis Prevention and Control Directorate of the Ministry of Health of Peru. Adult patients who started treatment with the scheme for drug-sensitive TB in 2016, 2017 and 2018 were included. We carried out a descriptive analysis of patients with TB and DM, and an exploratory analysis to assess the association of DM with mortality using a Poisson regression to determine the relative risk (RR). Results: We registered 67,524 adults with drug-sensitive TB, of which 6,529 (9.7%) people were reported as having TB and DM; and 4,048 (6.0%) had HIV infection. Of the patients reported with TB and DM, most were men (60.2%) with a median age of 53 years. Regarding mortality, people with TB and DM had a higher frequency of death compared to those with TB without DM (7.2% vs 5.4%). In the exploratory analysis of factors associated with mortality, DM had a crude RR of 1.32 (95% CI: 1.20-1.50); however, this association varied in the adjusted model with a RR of 0.93 (95% CI: 0.84-1.04). Conclusions: DM is the most frequent comorbidity in patients with TB in Peru, although no association with higher mortality was found.

RESUMO Objetivo: Identificar os preditores de doença arterial coronária em sobreviventes à parada cardíaca, visando definir o melhor momento para realização de angiografia coronária e estabelecer o relacionamento entre doença arterial coronária e mortalidade. Métodos: Este foi um estudo retrospectivo em centro único, que incluiu os pacientes consecutivamente submetidos à angiografia coronária após uma parada cardíaca. Resultados: Incluímos 117 pacientes (63 ± 13 anos, 77% homens). A maioria dos incidentes de parada cardíaca ocorreu com ritmos chocáveis (70,1%), e o tempo mediano até retorno da circulação espontânea foi de 10 minutos. Identificou-se doença arterial coronária em 68,4% dos pacientes, dentre os quais 75% foram submetidos à intervenção coronária percutânea. Elevação do segmento ST (RC de 6,5; IC95% 2,2 - 19,6; p = 0,001), presença de alterações da contratilidade segmentar (RC de 22,0; IC95% 5,7 - 84,6; p < 0,001), fração de ejeção ventricular esquerda ≤ 40% (RC de 6,2; IC95% 1,8 - 21,8; p = 0,005) e níveis elevados de troponina T de alta sensibilidade (RC de 3,04; IC95% 1,3 - 6,9; p = 0,008) foram preditores de doença arterial coronária; esse último teve baixa precisão (área sob a curva de 0,64; p = 0,004), tendo o nível de 170ng/L como ponto ideal de corte. Apenas elevação do segmento ST e presença de alterações da contratilidade segmentar foram preditores independentes de doença arterial coronária. A duração da parada cardíaca (RC de 1,015; IC95% 1,0 - 1,05; p = 0,048) foi um preditor independente de óbito, e ritmo chocável (RC de 0,4; IC95% 0,4 - 0,9; p = 0,031) foi um preditor independente de sobrevivência. A presença de doença arterial coronária e a realização de intervenção coronária percutânea não tiveram impacto na sobrevivência; não foi possível estabelecer o melhor ponto de corte para o momento da angiografia coronária. Conclusão: Em pacientes com parada cardíaca, elevação do segmento ST, alterações da contratilidade segmentar, disfunção ventricular esquerda e níveis elevados de troponina T de alta sensibilidade foram preditivos de doença arterial coronária. Nem doença arterial coronária nem a intervenção coronária percutânea tiveram impacto significante na sobrevivência.