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Background: Non-suicidal self-injury (NSSI) may be understood as a physical and behavioral expression of emotional distress. Over the past 70 years, it has been variably formulated as a type of emotional reaction to various stressors. NSSI has complex goals, sometimes implicit, but overall it serves as a transient psychological relief. Many believe that NSSI is a maladaptive behavior and is not related to suicide, with the primary differentiating factor between suicide and NSSI being the ‘intention’ to die. NSSI is an important mental health problem in current modern societies, and it is part of a trend in current psychiatric and mental health practice to medicalize maladaptive behaviors or psychological distress. Aims: To review the prevalence, associated factors, purpose, and psychological and social significance of NSSI in developing countries. Method: This article is a narrative review. However, of the total 1,094 articles, 13 articles were included to derive information on the prevalence and methods of NSSI in the developing country. Results: NSSI rates are very variable, ranging from 11.5% to as high as 33.8%, depending on the nature of the sample and study design, but data show an increasing trend globally, including in developing countries. Conclusion: The recent emerging data does not support the notion that it is common in developed Western countries, though the meaning, context and reason for NSSI might differ in developing and developed countries. NSSI is almost equally prevalent in both developing and developed countries.

Mitral annular calcification (MAC) is a chronic degenerative condition that is associated with age, chronic kidney disease, diabetes, dyslipidemia, hypertension, and tobacco use. Mobile calcified lesions can be mistaken for endocarditis on trans-thoracic echocardiogram (TTE), creating a unique diagnostic challenge. In this case, we describe a young dialysis patient who presented with dyspnea on exertion with no obvious etiology on initial work-up. TTE was obtained, which showed mobile lesions on the mitral and aortic valves, initially thought to be endocarditis, but later diagnosed as MAC. Trans-esophageal echocardiography (TEE) is a useful modality to differentiate mobile masses on the mitral valve.