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Introduction: Coronavirus Disease 2019, or better known as the COVID-19, has caused a global pandemic and high death rate worldwide. Following the rapid increase of COVID-19 cases in Malaysia, the government had enforced Movement Control Order (MCO) started from 18 March 2020 and the restrictions were conducted and reviewed in several phases. The MCO also involved schools closure and commencement of online learning. This study aimed to identify the level of knowledge, attitudes and practices regarding COVID-19 among students in selected boarding schools in Malaysia. Methodology: This cross-sectional study was done in July to September 2020 using a set of questionnaire that was distributed via Google form. The questionnaire consisted of demographic data, knowledge, attitude and practice regarding COVID-19. The data was analysed using the Statistical Package for the Social Science 22. Results: A total of 365 students participated in this study. The respondents comprised of 54.2% female and 45.8% male students. The study found that they have moderate knowledge on COVID-19 while their attitude and practice were high. The study found a significant association between the knowledge and practice scores and between the attitude and practice scores of the respondents. [r = 0.389, p < 0.05] regarding COVID-19 However, there was no significant association between the knowledge and attitude scores. Conclusions: This study concluded that students' practice regarding COVID-19 was influenced by their attitude on health care to prevent COVID-19 infection. Therefore, changing their attitude and increasing the students knowledge are necessary to improve their practices regarding COVID-19 preventive measures. [ABSTRACT FROM AUTHOR]

Background: COVID-19 is an emerging infectious disease caused by a novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In Malaysia, first few cases of COVID-19 were detected in January 2020, among Chinese nationals and the cases keep increasing day by day. Methods: This self-administered web based cross sectional study using Google forms was conducted among 400 Malaysian adults to explore their level of knowledge, attitude and practice towards COVID-19, as well as factors associated with the variables. Descriptive and binary logistic regression were performed using SPSS version 22. Results: Knowledge and practice among Malaysian adults towards COVID-19 were low. Gender (p = 0.030, OR:0.616, 95% CI 0.398-0.955) and occupation (p = 0.002, OR:2.489, 95% CI 1.485-4.172) were found as significant predictors of practice towards COVID-19. Conclusions: In conclusion, proper mass public health messages should be conducted by the higher authorities to improve knowledge and practice towards COVID-19. [ABSTRACT FROM AUTHOR]

Introduction: The world has been badly affected by the spread of a novel virus known as Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) that was first reported in Wuhan, China back in December 2019. As the virus is transmitted through aerosol, respiratory droplets and close contact, hand hygiene and wearing mask are the most important preventive measures for COVID-19. Studies showed hand hygiene intervention improved compliances. This paper discussed the development of a hand hygiene intervention module, validation, usability and effectiveness reports. Methods: This study involved 5 stages; need analysis, module development, validation, usability and effectiveness studies. Need analysis and module development were carried out through brainstorming and literature search. The content was evaluated by three experts, whereas the usability was screened by four preschool teachers. The effectiveness of knowledge transfer was evaluated via pre and post intervention surveys. Results: The hand hygiene educational module received valuable comments from the content expert and the end-users (teachers). Knowledge score related to COVID-19 transmission, prevention and hand hygiene moments among pre-school children were significantly increased after the intervention. Conclusion: This module can be used to improve teaching method related to COVID-19 and hand hygiene. The 'learn and play' approach may increase excitement, thus make learning process enjoyable and memorable. [ABSTRACT FROM AUTHOR]

Introduction: The world has been badly affected by the spread of a novel virus known as Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) that was first reported in Wuhan, China back in December 2019. As the virus is transmitted through aerosol, respiratory droplets and close contact, hand hygiene and wearing mask are the most important preventive measures for COVID-19. Studies showed hand hygiene intervention improved compliances. This paper discussed the development of a hand hygiene intervention module, validation, usability and effectiveness reports. Methods: This study involved 5 stages; need analysis, module development, validation, usability and effectiveness studies. Need analysis and module development were carried out through brainstorming and literature search. The content was evaluated by three experts, whereas the usability was screened by four preschool teachers. The effectiveness of knowledge transfer was evaluated via pre and post intervention surveys. Results: The hand hygiene educational module received valuable comments from the content expert and the end-users (teachers). Knowledge score related to COVID-19 transmission, prevention and hand hygiene moments among pre-school children were significantly increased after the intervention. Conclusion: This module can be used to improve teaching method related to COVID-19 and hand hygiene. The 'learn and play' approach may increase excitement, thus make learning process enjoyable and memorable. [ABSTRACT FROM AUTHOR]

Myasthenia gravis (MG) is an immune mediated neuromuscular disease causing fatiguability, which can influence quality of life (QOL). MG disease status can be established with Myasthenia Gravis Quality of Life (MGQOL) 15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires to measure patients' perception of MG-related dysfunction. This study aims to validate the translated Malay versions of the MGQOL15 and MGADL for use in Malay-speaking MG patients. By using the cross cultural adaptation process, both questionnaires were translated into Malay language. Two sets of MGQOL15 Malay version and MGADL Malay version were distributed to MG patients during their routine follow-up to be filled up one week apart. A total of 38 patients were recruited during this study comprising predominantly females compared to males (71% vs 29%) and Malays compared to non-Malays (60% vs 40%). The mean age was 52.5 years; with most of the patients in the 60-69 years old category (37%).The Spearman's correlation coefficient was 0.987 for MGQOL-15 Malay version and 0.976 for MGADL Malay version, while the internal consistency for MGQOL15 Malay version was 0.952-0.957, and 0.677-0.694 for MGADL Malay version. The MGQOL15 Malay version and MGADL Malay version are reliable and valid instruments for the measurement of quality of life in MG patients in the local setting. [ABSTRACT FROM AUTHOR]

Pregnancy-associated spontaneous coronary artery dissection (P-SCAD) is one of the fatal conditions that most commonly causes pregnancy-associated myocardial infarction. We herein report a case of P-SCAD in a 26-year-old multigravida woman, who complained of angina postpartum with raised cardiac biomarkers and transient ST-segment elevation on electrocardiograms. We emphasize the importance of a high degree of suspicion in the diagnosis of P-SCAD, together with the common presentation, the management approach, and its psychological impacts on the patients. [ABSTRACT FROM AUTHOR]

Introduction: Tropical herbs are used as a medicine long before the introduction of modern medicine, especially by traditional healers. However, its' scientific benefits are not widely investigated. There is a belief that the use of traditional herbs potentially causing health deterioration due to its unknown mechanism of actions and interactions, and the nature of its unregulated processing as a health supplement. Parkia speciosa (local: petai) and Pithecellobium jiringa (local: jering) are two tropical herbs from the Leguminosae family that are widely used raw as salads with many perceived health benefits and harms. We reviewed both species, looking into scientific pieces of evidence supporting the belief. Methods: The databases of MEDLINE, PubMed, EBSCOhost, and Google Scholars were systematically searched for both in vitro and in vivo effects of both species with no language restriction. Data were extracted using standardised fashioned. Results: P speciosa has pharmacological properties including antioxidant and anti-inflammation. It has shown to have antibacterial properties and glucose-lowering activity. P jiringa contains known antioxidant metabolites such as flavonoids, phenolics and terpenoids. It also contains antiangiogenic properties with potential use in retinopathy, cancer, and Rheumatoid arthritis. However, both herbs have potentially harmful effects which include liver injuries. Large consumption of P jiringa leads to acute kidney injury. Conclusion: Consumption of both P speciosa and P jiringa has medicinal properties as well as health harm. If taken as a supplement, rigorous clinical trials are needed to delineate benefit vs harm effect of both herbs. [ABSTRACT FROM AUTHOR]

Unlabelled: Rheumatoid arthritis is one of the commonest autoimmune diseases. It is a chronic, progressive, systemic inflammatory disorder affecting the synovial joints and typically producing symmetrical arthritis. If left untreated, it leads to joint destruction and thus deformity and disability.In the recent years, advances in molecular biology have led to a variety of new treatment approaches to rheumatoid arthritis and other systemic inflammatory diseases associated with autoimmunity. Anti tumor necrosis factor (TNF) agents are emerging in the frontline management of rheumatoid arthritis (RA) in the current era of biological treatment. We presented a 46-year-old Chinese female with a history of seropositive RA for the past 22 years refractory and intolerant to multiple medications including sulphasalazine (SSZ), leflunomide, hydroxychloroquine (HCQ) and methotrexate (MTX), thus infliximab, a tumor necrosis factor (TNF) inhibitor was initiated. However, despite receiving 6 cycles of infliximab therapy, she still complained of persistent disabled multiple joint pain and swelling. This report will discuss about rheumatoid arthritis, which is refractory to infliximab (a TNF inhibitor) and its alternative., Keywords: Rheumatoid arthritis; Biologics treatment; Tumor-necrosis factor inhibitor; Infliximab.