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5. MP12-07 THE RELATIONSHIP BETWEEN FRAILTY AND INSTRUMENTAL ACTIVITIES OF DAILY LIVING AND ITS IMPACT ON QUALITY-OF-LIFE IN PATIENTS WITH UROLOGICAL CANCERS

Author

Yoneyama, Fumiya, primary, Hatakeyama, Shingo, additional, Soma, Osamu, additional, Ozaki, Yusuke, additional, Narita, Takuma, additional, Fujita, Naoki, additional, Okamoto, Teppei, additional, Yamamoto, Hayato, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, and Oyama, Chikara, additional

Published
2024
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9. Relationship between lower urinary tract symptoms and frailty

Author

Ozaki, Yusuke, primary, Hatakeyama, Shingo, additional, Imai, Atsushi, additional, Songee, Jung, additional, Soma, Osamu, additional, Ozaki, Kai, additional, Fujita, Naoki, additional, Okamoto, Teppei, additional, Iwamura, Hiromichi, additional, Yamamoto, Hayato, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, and Ohyama, Chikara, additional

Published
2023
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10. PD19-06 IMPACT OF ACUTE KIDNEY INJURY ON FUTURE CARDIOVASCULAR DISEASE EVENTS AND RENAL IMPAIRMENT IN PATIENTS WITH UROLOGICAL SEPSIS

Author

Fujita, Naoki, primary, Momota, Masaki, additional, Soma, Osamu, additional, Noro, Daisuke, additional, Mikami, Jotaro, additional, Hatakeyama, Shingo, additional, Ito, Hiroyuki, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Yoshikawa, Kazuaki, additional, and Ohyama, Chikara, additional

Published
2023
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12. Multicenter prospective study validating the efficacy of a quantitative assessment tool for frailty in patients with urological cancers

Author

Soma, Osamu, Hatakeyama, Shingo, Okamoto, Teppei, Fujita, Naoki, Hamano, Itsuto, Tanaka, Toshikazu, Momota, Masaki, Yoneyama, Tohru, Yamamoto, Hayato, Imai, Atsushi, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Yoshikawa, Kazuaki, Kawaguchi, Toshiaki, Saitoh, Hisao, Nakaji, Shigeyuki, Suzuki, Tadashi, and Ohyama, Chikara

Published
2019
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13. Utility of the Age Discrepancy between Frailty-Based Biological Age and Expected Life Age in Patients with Urological Cancers

Author

Togashi, Kyo, primary, Hatakeyama, Shingo, additional, Soma, Osamu, additional, Okita, Kazutaka, additional, Fujita, Naoki, additional, Tanaka, Toshikazu, additional, Noro, Daisuke, additional, Horiguchi, Hirotaka, additional, Uemura, Nozomi, additional, Iwane, Takuro, additional, Okamoto, Teppei, additional, Yamamoto, Hayato, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, and Ohyama, Chikara, additional

Published
2022
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16. Solitary Fibrous Tumor of the Prostate Which Was Initially Misdiagnosed as Prostate Cancer

Author

Soma Osamu, Hiromi Murasawa, Atsushi Imai, Shingo Hatakeyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, and Chikara Ohyama

Subjects
Diseases of the genitourinary system. Urology, RC870-923
Abstract

Solitary fibrous tumor (SFT) of the prostate is a very rare tumor. We report a case of 65-year-old man with SFT of the prostate which was initially misdiagnosed as prostate cancer. Finally, we performed total prostatectomy and the tumor was histologically diagnosed as SFT of the prostate. The patient’s clinical course has progressed favorably with no obvious recurrence 18 months postoperatively.

Published
2017
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19. Geriatric 8 screening of frailty in patients with prostate cancer

Author

Momota, Masaki, primary, Hatakeyama, Shingo, additional, Soma, Osamu, additional, Tanaka, Toshikazu, additional, Hamano, Itsuto, additional, Fujita, Naoki, additional, Okamoto, Teppei, additional, Yoneyama, Tohru, additional, Yamamoto, Hayato, additional, Imai, Atsushi, additional, Yoshikawa, Kazuaki, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, and Ohyama, Chikara, additional

Published
2020
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20. Frailty is significantly associated with the type of urinary diversion in patients with muscle‐invasive bladder cancer

Author

Okita, Kazutaka, primary, Hatakeyama, Shingo, additional, Momota, Masaki, additional, Soma, Osamu, additional, Hamano, Itsuto, additional, Tanaka, Toshikazu, additional, Iwamura, Hiromichi, additional, Fujita, Naoki, additional, Okamoto, Teppei, additional, Yamamoto, Hayato, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Yoshikawa, Kazuaki, additional, Kawaguchi, Toshiaki, additional, and Ohyama, Chikara, additional

Published
2020
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21. Frailty is a predictor of moderate to severe pain after robot‐assisted laparoscopic prostatectomy: A case‐control study (FRAP study)

Author

Momota, Masaki, primary, Hatakeyama, Shingo, additional, Soma, Osamu, additional, Hamano, Itsuto, additional, Fujita, Naoki, additional, Okamoto, Teppei, additional, Togashi, Kyo, additional, Hamaya, Tomoko, additional, Yoneyama, Tohru, additional, Yamamoto, Hayato, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, and Ohyama, Chikara, additional

Published
2020
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23. Serum N-glycan profiling can predict biopsy-proven graft rejection after living kidney transplantation

Author

Soma, Osamu, primary, Hatakeyama, Shingo, additional, Yoneyama, Tohru, additional, Saito, Mitsuru, additional, Sasaki, Hideo, additional, Tobisawa, Yuki, additional, Noro, Daisuke, additional, Suzuki, Yuichiro, additional, Tanaka, Masakazu, additional, Nishimura, Shin-Ichiro, additional, Harada, Hiroshi, additional, Ishida, Hideki, additional, Tanabe, Kazunari, additional, Satoh, Shigeru, additional, and Ohyama, Chikara, additional

Published
2019
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24. Management of High-Risk Prostate Cancer and Left Ectopic Ureter Inserting into Seminal Vesicle with Ipsilateral Hypoplastic Kidney of a Young Patient : A Case Report

Author

Matsumoto, Teppei, Koie, Takuya, Soma, Osamu, Kusaka, Ayumu, Hosogoe, Shogo, Hamano, Itsuto, Imai, Atsushi, Hatakeyama, Shingo, Yoneyama, Takahiro, Hashimoto, Yasuhiro, and Ohyama, Chikara

Subjects
Prostate cancer, Ectopic ureter, Hypoplastic kidney, 494.9, Young patient
Abstract

A 44-year-old male patient visited our hospital with a chief complaint of macroscopic hematuria. Prostate biopsies were performed due to prostate specific antigen (PSA) 11.6 ng/ml, and he was diagnosed with Gleason score 5＋4 prostate cancer. Computed tomography showed a left hypoplastic kidney. T2- weighted magnetic resonance imaging showed the left ureter stump with ectopic insertion into the dilated left seminal vesicle. He was diagnosed with high-risk prostate cancer and left ectopic ureter inserting into the seminal vesicle with ipsilateral hypoplastic kidney. Laparoscopic left nephroureterectomy and open radical prostatectomy were performed.

Published
2016

26. Relationship between frailty and lower urinary tract symptoms among community‐dwelling adults

Author

Soma, Osamu, primary, Hatakeyama, Shingo, additional, Imai, Atsushi, additional, Matsumoto, Teppei, additional, Hamano, Itsuto, additional, Fujita, Naoki, additional, Iwamura, Hiromichi, additional, Okamoto, Teppei, additional, Yamamoto, Hayato, additional, Tobisawa, Yuki, additional, Yoneyama, Tohru, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Nakaji, Shigeyuki, additional, and Ohyama, Chikara, additional

Published
2019
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29. MP70-08 LONGITUDINAL SERUM N-GLYCAN PROFILING PREDICT BIOPSY-PROVEN GRAFT REJECTION AFTER A LIVING DONOR KIDNEY TRANSPLANTATION

Author

Soma*, Osamu, primary, Hatakeyama, Shingo, additional, Yoneyama, Tohru, additional, Noro, Daisuke, additional, Tobisawa, Yuki, additional, Hashimoto, Yasuhiro, additional, Koie, Takuya, additional, Nishimura, Shin-Ichiro, additional, Sasaki, Hideo, additional, Saito, Mitsuru, additional, Harada, Hiroshi, additional, Chikaraishi, Tatsuya, additional, Ishida, Hideki, additional, Tanabe, Kazunari, additional, Satoh, Shigeru, additional, and Ohyama, Chikara, additional

Published
2019
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30. Renal cell carcinoma in a lumbar ectopic kidney

Author

Hamano, Itsuto, primary, Hatakeyama, Shingo, additional, Soma, Osamu, additional, Ishibashi, Yusuke, additional, Yoneyama, Tohru, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Nishimura, Shoji, additional, Koie, Takuya, additional, and Ohyama, Chikara, additional

Published
2019
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31. Clinical impact of Bacillus Calmette-Guérin (BCG) Therapy on prognosis in patients with carcinoma in situ (CIS) of the upper urinary tract: A retrospective comparison with nephroureterectomy.

Author

Yoneyama, Takahiro, primary, Soma, Osamu, additional, Suzuki, Yuuichiro, additional, Yoneyama, Tohru, additional, Mori, Kazuyuki, additional, Yamamoto, Hayato, additional, Imai, Atsushi, additional, Hatakeyama, Shingo, additional, Hashimoto, Yasuhiro, additional, and Ohyama, Chikara, additional

Published
2019
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32. Solitary Fibrous Tumor of the Prostate Which Was Initially Misdiagnosed as Prostate Cancer

Author

Shingo Hatakeyama, Chikara Ohyama, Takuya Koie, Takahiro Yoneyama, Soma Osamu, Hiromi Murasawa, Yasuhiro Hashimoto, and Atsushi Imai

Subjects
medicine.medical_specialty, Solitary fibrous tumor, Pathology, business.industry, 030232 urology & nephrology, Clinical course, Case Report, General Medicine, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, medicine.disease, 03 medical and health sciences, Prostate cancer, Rare tumor, 0302 clinical medicine, medicine.anatomical_structure, Prostate, 030220 oncology & carcinogenesis, Total prostatectomy, medicine, Radiology, business
Abstract

Solitary fibrous tumor (SFT) of the prostate is a very rare tumor. We report a case of 65-year-old man with SFT of the prostate which was initially misdiagnosed as prostate cancer. Finally, we performed total prostatectomy and the tumor was histologically diagnosed as SFT of the prostate. The patient’s clinical course has progressed favorably with no obvious recurrence 18 months postoperatively.

Published
2017

33. Clinical implication of a simple quantitative frailty assessment tool for prognosis in patients with urological cancers

Author

Ayumu Kusaka, Takahiro Yoneyama, Shigeyuki Nakaji, Soma Osamu, Yasuhiro Hashimoto, Tohru Yoneyama, Chikara Ohyama, Teppei Matsumoto, Atsushi Imai, Takuya Koie, Yuki Tobisawa, Itsuto Hamano, Shingo Hatakeyama, Hayato Yamamoto, and Shogo Hosogoe

Subjects
medicine.medical_specialty, business.industry, Urology, medicine, In patient, Intensive care medicine, business, Urological cancers, Simple (philosophy), Frailty assessment
Published
2018

34. Relationship between frailty and lower urinary tract symptoms among community‐dwelling adults.

Author

Soma, Osamu, Hatakeyama, Shingo, Imai, Atsushi, Matsumoto, Teppei, Hamano, Itsuto, Fujita, Naoki, Iwamura, Hiromichi, Okamoto, Teppei, Yamamoto, Hayato, Tobisawa, Yuki, Yoneyama, Tohru, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Nakaji, Shigeyuki, and Ohyama, Chikara

Subjects
*URINARY organs, *LOGISTIC regression analysis, *OVERACTIVE bladder, *PHYSICAL activity, *HEALTH promotion
Abstract

Objectives: To evaluate the relationship between frailty and lower urinary tract symptoms (LUTS), the association of frailty and LUTS remains unclear. Methods: This cross‐sectional study investigated LUTS and frailty in 710 individuals (249 men and 461 women, aged ≥60 years) who participated in the Iwaki Health Promotion Project between 2014 and 2015 in Hirosaki, Japan. Parameters of frailty were compared for individuals with mild and moderate to severe symptoms of LUTS. The International Prostate Symptom Score (IPSS) and Overactive Bladder Symptom Score (OABSS) were used to evaluate LUTS. Frailty was evaluated by the frailty phenotype (FP), modified frailty index (mFI), and frailty discriminant score (FDS). The influence of frailty on LUTS was investigated by multivariate logistic regression analyses. Results: Frailty parameters of age, renal function, and lower physical activity were significantly associated with severity of IPSS and OABSS. FP and mFI were significantly associated with severity of OABSS and IPSS, respectively. The FDS was significantly associated with severity of IPSS and OABSS. FP, mFI, and FDS were significantly associated with severity of nocturia. Multivariate logistic regression analyses revealed that FDS was independently associated with the severity of IPSS, OABSS, and nocturia, whereas FP and mFI were significantly associated with the severity of nocturia alone. Conclusions: Individuals with LUTS are potentially frailer than those without LUTS. Although the influence of frailty on LUTS is different depending on the measurement tool, attention for frailty is necessary for subjects with LUTS. [ABSTRACT FROM AUTHOR]

Published
2020
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35. Clinical implication of a quantitative frailty assessment tool for prognosis in patients with urological cancers

Author

Soma, Osamu, primary, Hatakeyama, Shingo, additional, Okamoto, Teppei, additional, Fujita, Naoki, additional, Matsumoto, Teppei, additional, Tobisawa, Yuki, additional, Yoneyama, Tohru, additional, Yamamoto, Hayato, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Koie, Takuya, additional, Nakaji, Shigeyuki, additional, and Ohyama, Chikara, additional

Published
2018
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36. MP78-14 POTENTIAL PREDICTORS FOR THE UNDER-REPORTING BETWEEN PATIENT-REPORTED AND DOCTOR-REPORTED OUTCOMES IN ADVANCED UROTHELIAL CARCINOMA

Author

Hamano, Itsuto, primary, Hatakeyama, Shingo, additional, Matsumoto, Teppei, additional, Soma, Osamu, additional, Kusaka, Ayumu, additional, Hosogoe, Shogo, additional, Tobisawa, Yuki, additional, Yoneyama, Tohru, additional, Yamamoto, Hayato, additional, Imai, Atsushi, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Koie, Takuya, additional, and Ohyama, Chikara, additional

Published
2018
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37. MP47-07 PREOPERATIVE CHRONIC KIDNEY DISEASE PREDICTS POOR ONCOLOGICAL OUTCOMES AFTER RADICAL CYSTECTOMY IN PATIENTS WITH MUSCLE-INVASIVE BLADDER CANCER

Author

Hamano, Itsuto, primary, Hatakeyama, Shingo, additional, Matsumoto, Teppei, additional, Soma, Osamu, additional, Kusaka, Ayumu, additional, Hosogoe, Shogo, additional, Tobisawa, Yuki, additional, Yoneyama, Tohru, additional, Yamamoto, Hayato, additional, Imai, Atsushi, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Koie, Takuya, additional, Ito, Hiroyuki, additional, Yoshikawa, Kazuaki, additional, Kawaguchi, Toshiaki, additional, and Ohyama, Chikara, additional

Published
2018
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38. Clinical relevance of aortic calcification in urolithiasis patients

Author

Tanaka, Toshikazu, Hatakeyama, Shingo, Yamamoto, Hayato, Narita, Takuma, Hamano, Itsuto, Matsumoto, Teppei, Soma, Osamu, Tobisawa, Yuki, Yoneyama, Tohru, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Koie, Takuya, Takahashi, Ippei, Nakaji, Shigeyuki, Terayama, Yuriko, Funyu, Tomihisa, Ohyama, Chikara, Tanaka, Toshikazu, Hatakeyama, Shingo, Yamamoto, Hayato, Narita, Takuma, Hamano, Itsuto, Matsumoto, Teppei, Soma, Osamu, Tobisawa, Yuki, Yoneyama, Tohru, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Koie, Takuya, Takahashi, Ippei, Nakaji, Shigeyuki, Terayama, Yuriko, Funyu, Tomihisa, and Ohyama, Chikara

Abstract

Background: The aim of the present study is to investigate the clinical relevance of aortic calcification in urolithiasis patients. Methods: Between January 2010 and September 2014, 1221 patients with urolithiasis were treated in Oyokyo Kidney Research Institute and Hirosaki University Hospital. Among these, 287 patients( Stone group) on whom adequate data were available were included in this retrospective study. We also selected 148 subjects with early stage( pT1N0M0) renal cell carcinoma from 607 renal cell carcinoma patients who underwent radical nephrectomy at Hirosaki University Hospital( Non-stone group) as control subjects. Validity of the Non-stone group was evaluated by comparison with pair-matched 296 volunteers from 1166 subjects who participated in the Iwaki Health Promotion Project in 2014. Thereafter, age, body mass index, aortic calcification index( ACI), renal function, serum uric acid concentrations, and comorbidities( diabetes, hypertension, or cardiovascular disease) were compared between the Non-stone and Stone groups. Independent factors for higher ACI and impaired renal function were assessed using multivariate logistic regression analysis. Results: We confirmed relevance of Non-stone group patients as a control subject by comparing the pairmatched community-dwelling volunteers. Backgrounds of patients between the Non-stone and Stone groups were not significantly different except for the presence of hypertension in the Stone group. ACI was not significantly high in the Stone group compared with the Non-stone group. However, age-adjusted ACI was greater in the Stone group than the Non-stone group. Among urolithiasis patients, ACI was significantly higher in uric acid containing stone patients. The number of patients with stage 3B chronic kidney disease( CKD) was significantly higher in the Stone group than in the Non-stone group( 12% vs. 4%, P = 0.008). Multivariate logistic regression analysis showed higher aortic calcification index(>13%), and

Published
2017

39. Preoperative chronic kidney disease predicts poor oncological outcomes after radical nephroureterectomy in patients with upper urinary tract urothelial carcinoma

Author

Kodama, Hirotake, Hatakeyama, Shingo, Fujita, Naoki, Iwamura, Hiromichi, Anan, Go, Fukushi, Ken, Narita, Takuma, Tanaka, Toshikazu, Kubota, Yuka, Horiguchi, Hirotaka, Momota, Masaki, Kido, Koichi, Matsumoto, Teppei, Soma, Osamu, Hamano, Itsuto, Yamamoto, Hayato, Tobisawa, Yuki, Yoneyama, Tohru, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Koie, Takuya, Ito, Hiroyuki, Yoshikawa, Kazuaki, Sasaki, Atsushi, Kawaguchi, Toshiaki, Sato, Makoto, Ohyama, Chikara, Kodama, Hirotake, Hatakeyama, Shingo, Fujita, Naoki, Iwamura, Hiromichi, Anan, Go, Fukushi, Ken, Narita, Takuma, Tanaka, Toshikazu, Kubota, Yuka, Horiguchi, Hirotaka, Momota, Masaki, Kido, Koichi, Matsumoto, Teppei, Soma, Osamu, Hamano, Itsuto, Yamamoto, Hayato, Tobisawa, Yuki, Yoneyama, Tohru, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Koie, Takuya, Ito, Hiroyuki, Yoshikawa, Kazuaki, Sasaki, Atsushi, Kawaguchi, Toshiaki, Sato, Makoto, and Ohyama, Chikara

Abstract

Objective: To evaluate the impact of preoperative chronic kidney disease (CKD) on oncological outcomes in patients with upper tract urothelial carcinoma who underwent radical nephroureterectomy. Methods: A total of 426 patients who underwent radical nephroureterectomy at five medical centers between February 1995 and February 2017 were retrospectively examined. Oncological outcomes, including intravesical recurrence-free, visceral recurrence-free, cancer-specific, and overall survival rates (intravesical RFS, visceral RFS, CSS, and OS, respectively) stratified by preoperative CKD status (CKD vs. non-CKD) were investigated. Cox proportional hazards regression analysis was performed using inverse probability of treatment weighting (IPTW) to evaluate the impact of preoperative CKD on prognosis and a prognostic factor-based risk stratification nomogram was developed. Results: Of the 426 patients, 250 (59%) were diagnosed with CKD before radical nephroureterectomy. Before the background adjustment, intravesical RFS, visceral RFS, CSS, and OS after radical nephroureterectomy were significantly shorter in the CKD group than in the non-CKD group. Background-adjusted IPTW analysis demonstrated that preoperative CKD was significantly associated with poor visceral RFS, CSS, and OS after radical nephroureterectomy. Intravesical RFS was not significantly associated with preoperative CKD. The nomogram for predicting 5-year visceral RFS and CSS probability demonstrated a significant correlation with actual visceral RFS and CSS (c-index = 0.85 and 0.83, respectively). Conclusions: Upper tract urothelial carcinoma patients with preoperative CKD had a significantly lower survival probability than those without CKD.

Published
2017

40. The influence of serum uric acid on renal function in patients with calcium or uric acid stone: A population-based analysis

Author

Tanaka, Yoshimi, Hatakeyama, Shingo, Tanaka, Toshikazu, Yamamoto, Hayato, Narita, Takuma, Hamano, Itsuto, Matsumoto, Teppei, Soma, Osamu, Okamoto, Teppei, Tobisawa, Yuki, Yoneyama, Tohru, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Koie, Takuya, Takahashi, Ippei, Nakaji, Shigeyuki, Terayama, Yuriko, Funyu, Tomihisa, Ohyama, Chikara, Tanaka, Yoshimi, Hatakeyama, Shingo, Tanaka, Toshikazu, Yamamoto, Hayato, Narita, Takuma, Hamano, Itsuto, Matsumoto, Teppei, Soma, Osamu, Okamoto, Teppei, Tobisawa, Yuki, Yoneyama, Tohru, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Koie, Takuya, Takahashi, Ippei, Nakaji, Shigeyuki, Terayama, Yuriko, Funyu, Tomihisa, and Ohyama, Chikara

Abstract

Objectives To determine the influence of serum uric acid (UA) levels on renal impairment in patients with UA stone. Materials and methods We retrospectively analyzed 463 patients with calcium oxalate and/or calcium phosphate stones (CaOx/CaP), and 139 patients with UA stones. The subjects were divided into the serum UA-high (UA > 7.0 mg/dL) or the UA-low group (UA < 7.0 mg/dL). The control group comprised 3082 community-dwelling individuals that were pair-matched according to age, sex, body mass index, comorbidities, hemoglobin, serum albumin, and serum UA using propensity score matching. We compared renal function between controls and patients with UA stone (analysis 1), and between patients with CaOx/CaP and with UA stone (analysis 2). Logistic regression analysis was used to evaluate the impact of the hyperuricemia on the development of stage 3 and 3B chronic kidney disease (CKD) (analysis 3). Results The renal function was significantly associated with serum UA levels in the controls and patients with CaOx/CaP and UA stones. In pair-matched subgroups, patients with UA stone had significantly lower renal function than the control subjects (analysis 1) and patients with CaOx/CaP stones (analysis 2) regardless of hyperuricemia. Multivariate logistic regression analysis revealed that patients with UA stone, CaOx/CaP, hyperuricemia, presence of cardiovascular disease, higher body mass index, older age and lower hemoglobin had significantly higher risk of stage 3 and 3B CKD (analysis 3). Conclusion Patients with UA stones had significantly worse renal function than controls and CaOx/CaP patients regardless of hyperuricemia. Urolithiasis (CaOx/CaP and UA stone) and hyperuricemia had an association with impaired renal function. Our findings encourage clinicians to initiate intensive treatment and education approaches in patients with urolithiasis and/or hyperuricemia in order to prevent the progression of renal impairment.

Published
2017

41. Aortic calcification burden predicts deterioration of renal function after radical nephrectomy

Author

Fukushi, Ken, Hatakeyama, Shingo, Yamamoto, Hayato, Tobisawa, Yuki, Yoneyama, Tohru, Soma, Osamu, Matsumoto, Teppei, Hamano, Itsuto, Narita, Takuma, Imai, Atsushi, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Koie, Takuya, Terayama, Yuriko, Funyu, Tomihisa, Ohyama, Chikara, Fukushi, Ken, Hatakeyama, Shingo, Yamamoto, Hayato, Tobisawa, Yuki, Yoneyama, Tohru, Soma, Osamu, Matsumoto, Teppei, Hamano, Itsuto, Narita, Takuma, Imai, Atsushi, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Koie, Takuya, Terayama, Yuriko, Funyu, Tomihisa, and Ohyama, Chikara

Abstract

Background: Radical nephrectomy for renal cell carcinoma (RCC) is a risk factor for the development of chronic kidney disease (CKD), and the possibility of postoperative deterioration of renal function must be considered before surgery. We investigated the contribution of the aortic calcification index (ACI) to the prediction of deterioration of renal function in patients undergoing radical nephrectomy. Methods: Between January 1995 and December 2012, we performed 511 consecutive radical nephrectomies for patients with RCC. We retrospectively studied data from 109 patients who had regular postoperative follow-up of renal function for at least five years. The patients were divided into non-CKD and pre-CKD based on a preoperative estimated glomerular filtration rate (eGFR) of >= 60 mL/min/1.73 m(2) or < 60 mL/min/1.73 m(2), respectively. The ACI was quantitatively measured by abdominal computed tomography before surgery. The patients in each group were stratified between low and high ACIs. Variables such as age, sex, comorbidities, and pre-and postoperative renal function were compared between patients with a low or high ACI in each group. Renal function deterioration-free interval rates were evaluated by Kaplan-Meier analysis. Factors independently associated with deterioration of renal function were determined using multivariate analysis. Results: The median age, preoperative eGFR, and ACI in this cohort were 65 years, 68 mL/min/1.73 m(2), and 8.3%, respectively. Higher ACI (>= 8.3%) was significantly associated with eGFR decline in both non-CKD and pre-CKD groups. Renal function deterioration-free interval rates were significantly lower in the ACI-high than ACI-low strata in both of the non-CKD and pre-CKD groups. Multivariate analysis showed that higher ACI was an independent risk factor for deterioration of renal function at 5 years after radical nephrectomy. Conclusions: Aortic calcification burden is a potential predictor of deterioration of renal function afte

Published
2017

42. Presence of transient hydronephrosis immediately after surgery has a limited influence on renal function 1 year after ileal neobladder construction

Author

Narita, Takuma, Hatakeyama, Shingo, Koie, Takuya, Hosogoe, Shogo, Matsumoto, Teppei, Soma, Osamu, Yamamoto, Hayato, Yoneyama, Tohru, Tobisawa, Yuki, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Ohyama, Chikara, Narita, Takuma, Hatakeyama, Shingo, Koie, Takuya, Hosogoe, Shogo, Matsumoto, Teppei, Soma, Osamu, Yamamoto, Hayato, Yoneyama, Tohru, Tobisawa, Yuki, Yoneyama, Takahiro, Hashimoto, Yasuhiro, and Ohyama, Chikara

Abstract

Background: Urinary tract obstruction and postoperative hydronephrosis are risk factor for renal function deterioration after orthotopic ileal neobladder construction. However, reports of relationship between transient hydronephrosis and renal function are limited. We assess the influence of postoperative transient hydronephrosis on renal function in patients with orthotopic ileal neobladder construction. Methods: Between January 2006 and June 2013, we performed radical cystectomy in 164 patients, and 101 received orthotopic ileal neobladder construction. This study included data available from 64 patients with 128 renal units who were enrolled retrospectively. The hydronephrosis grade of each renal unit scored 0-4. The patients were divided into 4 groups according to the grade of hydronephrosis: control, low, intermediate, and high. The grade of postoperative hydronephrosis was compared with renal function 1 month and 1 year after surgery. Results: There were no significant differences in renal function before surgery between groups. One month after surgery, the presence of hydronephrosis was significantly associated with decreased renal function. However, 1 year after urinary diversion hydronephrosis grades were improved significantly, and renal function was comparable between groups. Postoperative hydronephrosis at 1 month had no significant influence on renal function 1 year after ileal neobladder construction. Limitations include retrospective design, short follow-up periods, and a sample composition. Conclusions: The presence of transient hydronephrosis immediately after surgery may have limited influence on renal function 1 year after ileal neobladder construction.

Published
2017

43. Opacity of big toenail predicts poor prognosis in patients with end-stage renal disease on hemodialysis

Author

Soma, Osamu, primary, Hatakeyama, Shingo, additional, Matsumoto, Teppei, additional, Tanaka, Toshikazu, additional, Tanaka, Yoshimi, additional, Hosogoe, Shogo, additional, Kodama, Hirotake, additional, Horiguchi, Hirotaka, additional, Kubota, Yuka, additional, Kido, Koichi, additional, Momota, Masaki, additional, Anan, Go, additional, Narita, Ikuyo, additional, Kitahara, Ryuji, additional, Saitoh, Hisao, additional, Suzuki, Tadashi, additional, and Ohyama, Chikara, additional

Published
2017
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44. Presence of transient hydronephrosis immediately after surgery has a limited influence on renal function 1 year after ileal neobladder construction

Author

Narita, Takuma, primary, Hatakeyama, Shingo, additional, Koie, Takuya, additional, Hosogoe, Shogo, additional, Matsumoto, Teppei, additional, Soma, Osamu, additional, Yamamoto, Hayato, additional, Yoneyama, Tohru, additional, Tobisawa, Yuki, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, and Ohyama, Chikara, additional

Published
2017
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45. Preoperative chronic kidney disease predicts poor oncological outcomes after radical nephroureterectomy in patients with upper urinary tract urothelial carcinoma

Author

Kodama, Hirotake, primary, Hatakeyama, Shingo, additional, Fujita, Naoki, additional, Iwamura, Hiromichi, additional, Anan, Go, additional, Fukushi, Ken, additional, Narita, Takuma, additional, Tanaka, Toshikazu, additional, Kubota, Yuka, additional, Horiguchi, Hirotaka, additional, Momota, Masaki, additional, Kido, Koichi, additional, Matsumoto, Teppei, additional, Soma, Osamu, additional, Hamano, Itsuto, additional, Yamamoto, Hayato, additional, Tobisawa, Yuki, additional, Yoneyama, Tohru, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Koie, Takuya, additional, Ito, Hiroyuki, additional, Yoshikawa, Kazuaki, additional, Sasaki, Atsushi, additional, Kawaguchi, Toshiaki, additional, Sato, Makoto, additional, and Ohyama, Chikara, additional

Published
2017
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46. The influence of serum uric acid on renal function in patients with calcium or uric acid stone: A population-based analysis

Author

Tanaka, Yoshimi, primary, Hatakeyama, Shingo, additional, Tanaka, Toshikazu, additional, Yamamoto, Hayato, additional, Narita, Takuma, additional, Hamano, Itsuto, additional, Matsumoto, Teppei, additional, Soma, Osamu, additional, Okamoto, Teppei, additional, Tobisawa, Yuki, additional, Yoneyama, Tohru, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Koie, Takuya, additional, Takahashi, Ippei, additional, Nakaji, Shigeyuki, additional, Terayama, Yuriko, additional, Funyu, Tomihisa, additional, and Ohyama, Chikara, additional

Published
2017
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47. Clinical relevance of aortic calcification in urolithiasis patients

Author

Tanaka, Toshikazu, primary, Hatakeyama, Shingo, additional, Yamamoto, Hayato, additional, Narita, Takuma, additional, Hamano, Itsuto, additional, Matsumoto, Teppei, additional, Soma, Osamu, additional, Tobisawa, Yuki, additional, Yoneyama, Tohru, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Koie, Takuya, additional, Takahashi, Ippei, additional, Nakaji, Shigeyuki, additional, Terayama, Yuriko, additional, Funyu, Tomihisa, additional, and Ohyama, Chikara, additional

Published
2017
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48. MP86-02 PREVALENCE OF FRAILTY AMONG UROLOGICAL CANCER PATIENTS IN COMPARISON WITH COMMUNITY-DWELLING POPULATION

Author

Hatakeyama, Shingo, primary, Soma, Osamu, additional, Narita, Takuma, additional, Tanaka, Kazuhisa, additional, Tanaka, Toshikazu, additional, Noro, Daisuke, additional, Oikawa, Masaaki, additional, Tanaka, Yoshimi, additional, Matsumoto, Teppei, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Koie, Takuya, additional, and Ohyama, Chikara, additional

Published
2017
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50. Effect of heparin bridged transrectal prostate biopsy on the risk of hemorrhage in patients requiring temporary discontinuation of warfarin.

Author

Hamano, Itsuto, primary, Hatakeyama, Shingo, additional, Yoneyama, Tohru, additional, Tobisawa, Yuki, additional, Soma, Osamu, additional, Matsumoto, Teppei, additional, Yamamoto, Hayato, additional, Imai, Atsushi, additional, Yoneyama, Takahiro, additional, Hashimoto, Yasuhiro, additional, Koie, Takuya, additional, and Ohyama, Chikara, additional

Published
2017
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