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Your search keyword '"Somatic Hypermutation, Immunoglobulin genetics"' showing total 429 results

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429 results on '"Somatic Hypermutation, Immunoglobulin genetics"'

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1. The SV40 virus enhancer functions as a somatic hypermutation-targeting element with potential tumorigenic activity.

2. Molecular mechanisms of DNA lesion and repair during antibody somatic hypermutation.

3. Molecular mechanisms of avian immunoglobulin gene diversification and prospect for industrial applications.

4. Isotype-aware inference of B cell clonal lineage trees from single-cell sequencing data.

5. FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation.

6. Diversification of the VH3-53 immunoglobulin gene segment by somatic hypermutation results in neutralization of SARS-CoV-2 virus variants.

7. A branching stochastic evolutionary model of the B-cell repertoire.

8. Interpretable deep learning reveals the role of an E-box motif in suppressing somatic hypermutation of AGCT motifs within human immunoglobulin variable regions.

9. DNA flexibility can shape the preferential hypermutation of antibody genes.

10. Genetic Characteristics of Non B Cell-Derived Immunoglobulin Genes.

11. Mechanism and regulation of secondary immunoglobulin diversification.

12. Somatic hypermutation defects in two adult hyper immunoglobulin M patients.

13. Long-primed germinal centres with enduring affinity maturation and clonal migration.

14. AID function in somatic hypermutation and class switch recombination.

15. A Novel AICDA Splice-Site Mutation in Two Siblings with HIGM2 Permits Somatic Hypermutation but Abrogates Mutational Targeting.

16. RNA-directed DNA repair and antibody somatic hypermutation.

17. HMCES protects immunoglobulin genes specifically from deletions during somatic hypermutation.

18. The role of HIRA-dependent H3.3 deposition and its modifications in the somatic hypermutation of immunoglobulin variable regions.

19. FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.

20. Fam72a enforces error-prone DNA repair during antibody diversification.

21. A Small Step, a Giant Leap: Somatic Hypermutation of a Single Amino Acid Leads to Anti-La Autoreactivity.

22. Context-dependent regulation of immunoglobulin mutagenesis by p53.

23. Intrathymic differentiation of natural antibody-producing plasma cells in human neonates.

24. Defining HPV-specific B cell responses in patients with head and neck cancer.

25. Impact of Chk1 dosage on somatic hypermutation in vivo.

26. SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2.

27. Characterization of DLBCL with a PMBL gene expression signature.

28. Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas.

29. Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.

30. Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches.

31. Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells.

32. Genome-wide mutational signatures revealed distinct developmental paths for human B cell lymphomas.

33. Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.

34. Nurse shark T-cell receptors employ somatic hypermutation preferentially to alter alpha/delta variable segments associated with alpha constant region.

35. A Bayesian phylogenetic hidden Markov model for B cell receptor sequence analysis.

36. Lack of Evidence for a Substantial Rate of Templated Mutagenesis in B Cell Diversification.

37. Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation.

38. V(D)J recombination, somatic hypermutation and class switch recombination of immunoglobulins: mechanism and regulation.

39. BCR selection and affinity maturation in Peyer's patch germinal centres.

40. RNA-binding motifs of hnRNP K are critical for induction of antibody diversification by activation-induced cytidine deaminase.

41. What Targets Somatic Hypermutation to the Immunoglobulin Loci?

42. The Interplay between CD27 dull and CD27 bright B Cells Ensures the Flexibility, Stability, and Resilience of Human B Cell Memory.

43. AID Phosphorylation Regulates Mismatch Repair-Dependent Class Switch Recombination and Affinity Maturation.

44. Teleost IgD + IgM - B Cells Mount Clonally Expanded and Mildly Mutated Intestinal IgD Responses in the Absence of Lymphoid Follicles.

45. Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation.

46. Liver Is a Generative Site for the B Cell Response to Ehrlichia muris.

47. A Novel DT40 Antibody Library for the Generation of Monoclonal Antibodies.

48. Splicing regulator SRSF1-3 that controls somatic hypermutation of IgV genes interacts with topoisomerase 1 and AID.

49. Different antiviral activities of natural APOBEC3C, APOBEC3G, and APOBEC3H variants against hepatitis B virus.

50. Regulation of the Germinal Center Reaction and Somatic Hypermutation Dynamics by Homologous Recombination.

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