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Copyright of Humanities & Educational Sciences Journal is the property of Humanities & Educational Sciences Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The White-lipped Treefrog Zhangixalus pachyproctus Yu, Hui, Hou, Wu, Rao & Yang, 2019 was previously confused with Zhangixalus smaragdinus (Blyth, 1852). Records of Zhangixalus smaragdinus from Yunnan (China), Vietnam and Thailand were recognised as a misidentification and this taxon was subsequently described as a new species, based on morphological and molecular evidence. This species is currently known from southern China, Thailand, Laos and Vietnam. However, knowledge about its natural history and feeding ecology is virtually lacking.We herein report a newly-discovered population of Zhangixalus pachyproctus from Lang Son Province, northern Vietnam. In addition, we provide novel data about the diet of Z. pachyproctus, based on stomach content analyses of 38 individuals (37 males and one female). A total of 26 prey categories with 681 items were found in the stomachs of Z. pachyproctus. The dominant prey items of the species were Orthoptera (Acrididae, Tettigoniidae), Coleoptera (Languriida, Leiodidae, larvae, other Coleoptera), Mantodea (Mantidae) and Blattodea (Blaberidae, Blattidae, other Blattodea). Coleoptera (Coccinellidae, Cupedidae, Elateridae, Languriidae Leiodidae, Tenebrionidae, larvae and other Coleoptera) was the category with the highest frequency of prey items, found in 24 stomachs. The most important (IRI) groups amongst the prey of Z. pachyproctus were Coleoptera (24.52%) and followed by Orthoptera (24.43%), Blattodea (9.12%), Mantidae (8.14%) and Hemiptera (4.05%).

This article examines night-time bedroom soundscapes to highlight the significance of embodied geographies of home in understanding lived inequalities of housing. The article presents an analysis of responses (n =174) to the Mass Observation Project 'Your Bedroom' (2017) directive, in which UK panellists were asked about their bedrooms. The mundane, ordinary and frequent noise disturbance from neighbourhoods and neighbours is documented to contribute to an understanding of the sensory geographies of night-time domesticities. The article demonstrates that embodied experiences of night-time bedroom soundscapes, including sleep practices, are shaped by housing, including residential location, building type, and ownership/tenure. The article concludes by arguing that attention to soundscapes is significant in developing an embodied understanding of the inequalities of contemporary geographies of housing and home. [ABSTRACT FROM AUTHOR]

Problems: Problems in study This is Athletes often pay little attention to their psychological training methods, because they think that service is not that important, therefore imagery training is very important and is the solution in this research. Purpose: Internal goal study This is to know influence exercise imagery against accuracy service jump volleyball athlete​ son. Methods: Research This use method quantitative with approach experiment one group pre-test post-test design. Result: Research results show that exercise imagery give influence to accuracy volleyball athlete's service jump son by 26%. Conclusion: The implementation of appropriate and consistent imagery training has been proven effective in enhancing the accuracy of jump serves among male volleyball athletes. It is therefore recommended that volleyball coaches incorporate sustained imagery training into their training programs.

Abstract Background Lifestyle and habits, cardiovascular risk factors (CRF), bone and mental health, dietary habits, physical activity, among others are developed in childhood and adolescence. Family environment has shown to play an important role in these outcomes. However, whether the parent-child relationship lifestyle habits and health parameters can be influenced by physical activity patterns still unclear. The objective of this study will be to monitor and investigate the associations between lifestyle habits between parents and their children longitudinally, as well as verify whether in more active parents, the possible associations with lifestyle habits are different from those of parents considered less active. Methods The sample will consist of parents (father, mother, or both) and their children /adolescents. The participants will be recruited through public call by flyers spread across all the regions of the city and also through social media. The health parameters will include cardiovascular (cardiac autonomic modulation, blood pressure and resting heart rate), bone mineral density, anthropometric indices, handgrip strength, mental health (quality of life, anxiety and depression symptoms and stress), self-reported morbidities and musculoskeletal pain. Lifestyle habits will include physical activity levels, sedentary behavior, sleep parameters, eating patterns, smoking and alcohol consumption. Sociodemographic variables of age, sex, ethnicity and socioeconomic status will be considered as covariates. The follow-up visits of data collection will be scheduled after a period of 12 months from the baseline assessment during every twelve months. Discussion The family environment has great potential to determine lifestyle habits in children and adolescents. Based on the results presented in the present study, we hope that health promotion actions can be better designed in the family environment.

In Motivos de son (1930), Nicolás Guillén masterfully appropriates the distinctive characteristics of the Cuban musical genre known as son. This article explores the son -inspired aspects present in Guillén's poema-son. Special attention is given to the dialogue between the motivos and the musical heritage of emblematic ensembles such as the Sexteto Habanero—later Septeto—and the Trío Matamoros, pivotal in shaping the canon of the Cuban son. To fulfill the aspirations of this research, we delve into both the anthological themes of the aforementioned ensembles and the musical renditions of the motivos created by avant-garde composers Alejandro García Caturla, Amadeo Roldán, and the brothers Eliseo and Emilio Grenet, compiled in the fiftieth anniversary edition curated by Mirta Aguirre. This interdisciplinary approach allows us to unravel the profound connections between Guillén's poetry and son , while revealing its relation to teatro bufo , the immediate precursor of this musical genre. [ABSTRACT FROM AUTHOR]

Copyright of Itinerarios (1507-7241) is the property of University of Warsaw and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Philosophy, Culture & Political Science is the property of Al-Farabi Kazakh National University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Lifestyle and habits, cardiovascular risk factors (CRF), bone and mental health, dietary habits, physical activity, among others are developed in childhood and adolescence. Family environment has shown to play an important role in these outcomes. However, whether the parent-child relationship lifestyle habits and health parameters can be influenced by physical activity patterns still unclear. The objective of this study will be to monitor and investigate the associations between lifestyle habits between parents and their children longitudinally, as well as verify whether in more active parents, the possible associations with lifestyle habits are different from those of parents considered less active. Methods: The sample will consist of parents (father, mother, or both) and their children /adolescents. The participants will be recruited through public call by flyers spread across all the regions of the city and also through social media. The health parameters will include cardiovascular (cardiac autonomic modulation, blood pressure and resting heart rate), bone mineral density, anthropometric indices, handgrip strength, mental health (quality of life, anxiety and depression symptoms and stress), self-reported morbidities and musculoskeletal pain. Lifestyle habits will include physical activity levels, sedentary behavior, sleep parameters, eating patterns, smoking and alcohol consumption. Sociodemographic variables of age, sex, ethnicity and socioeconomic status will be considered as covariates. The follow-up visits of data collection will be scheduled after a period of 12 months from the baseline assessment during every twelve months. Discussion: The family environment has great potential to determine lifestyle habits in children and adolescents. Based on the results presented in the present study, we hope that health promotion actions can be better designed in the family environment. [ABSTRACT FROM AUTHOR]

Scholars have long debated whether 1 Corinthians is unified and, if so, whether the unity consists in an error on the side of the Corinthians and/or a theological or pastoral objective of Paul. The present argument is that the unifying thematic axis of 1 Corinthians as a letter consists in a Trinitarian knowledge of the God of Israel. This knowledge of God is given in Christ crucified and raised according to the Scriptures and through the Spirit, and this same knowledge addresses the twin concerns of idolatry and sexual immorality among the Corinthians. The epistle is accordingly an exercise in acknowledgment of God's revelation of himself to Paul and the churches and in doxological discipleship. If so, it follows that the unity of 1 Corinthians emerges from something prior to Paul and over his own intention, something self-commending even as it finds expression in Paul's written thought. God knows his people and is known in Christ through the Spirit by those whom he has raised with Christ to newness of life and filled with his Spirit. In this knowledge, they, the Israel of God, know where they have come from, who they are and must be, and where they are going. Everything Paul writes to them about all the gritty particulars of life derives from this reciprocal, lived knowledge. [ABSTRACT FROM AUTHOR]

Manipur, situated amidst a dynamic demographic landscape, stands as a notable region with elevated fertility rates within the broader context of India. Despite concerted efforts directed towards achieving stability in population growth as delineated in the National Population Policy (NPP) - 2000, there exists a conspicuous absence of community-based studies dedicated to unraveling the determinants of completed fertility in Manipur. This study endeavours to delve into the underlying socio-demographic factors contributing to the variations in completed fertility among menopausal women aged 50-55 years in Manipur. Conducted through a retrospective cross-sectional analysis, the study engaged 1129 ever-married women who have traversed menopause, within the districts of Imphal East and Imphal West in Manipur. Data collection transpired between August 2019 and June 2020, with 11th July 2019 designated as the reference date for the survey. Employing multiple binary logistic regression models, the investigation unveils significant associations between completed fertility with 3.2 births at an average and several key variables, notably education level (P<0.01), the sex of the second-born child (P<0.01), and the couple's inclination towards having a son (P<0.01). These findings not only furnish invaluable insights into the determinants of fertility within the context of Manipur but also serve as foundational knowledge for prospective research endeavours aimed at fostering maternal health development and aligning with the overarching objectives of India's national population control strategies. By comprehensively elucidating the socio-demographic nuances underpinning fertility patterns, this study paves the way for informed interventions and policy formulations geared towards ensuring sustainable population dynamics in Manipur and beyond. [ABSTRACT FROM AUTHOR]

Copyright of Environmental & Social Management Journal / Revista de Gestão Social e Ambiental is the property of Environmental & Social Management Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Drawing on interviews with British passport holders who moved to the United Kingdom to start University, this paper explores slang and accent as sonic spatial identities. The paper analyses the inclusions and exclusions in belonging as articulated by British mobile young people through their sonic spatial identities. In doing so, the paper extends wider conceptual debates on embodied belonging by arguing for a need to further explore the sonic as a register of belonging. It argues that research on sonic spatial identities needs to be more attuned to mobility in order to explore and challenge wider discourses of exclusion. The article concludes by offering suggestions as to how to develop research in belonging and identity on an everyday sonic register. [ABSTRACT FROM AUTHOR]

The article tries to show the role of the father in the light of the canons of the early Church, starting from the beginnings of Christianity until the year 600. It concerns issues such as the father's responsibility for the faith and salvation of children, proper upbringing of offspring, protection of children against various forms of violence, and providing the child with appropriate financial resources (maintaining) and maintaining the father's authority in the context of responsibility for one's word. [ABSTRACT FROM AUTHOR]

It is well-established that beige/brown adipose tissue can dissipate stored energy through thermogenesis; hence, the browning of white adipocytes (WAT) has garnered significant interest in contemporary research. Our preceding investigations have identified a marked downregulation of miR-889-3p concurrent with the natural maturation of brown adipose tissue. However, the specific role and underlying molecular mechanisms of miR-889-3p in the browning process of white adipose tissue warrant further elucidation. In this research, we initially delved into the potential role of miR-889-3p in preadipocyte growth via flow cytometry and CCK-8 assay, revealing that miR-889-3p can stimulate preadipocyte growth. To validate the potential contribution of miR-889-3p in the browning process of white adipose tissue, we established an in vitro rabbit white adipocyte browning induction, which exhibited a significant upregulation of miR-889-3p during the browning process. RT-qPCR and Western blot analysis indicated that miR-889-3p overexpression significantly amplified the mRNA levels of UCP1, PRDM16, and CIDEA, as well as UCP1 protein levels. Furthermore, miR-889-3p overexpression fostered intracellular triglyceride accumulation. Conversely, the downregulation of miR-889-3p hindered the browning of rabbit preadipocytes. Subsequently, based on target gene prediction and luciferase reporter gene determination, we demonstrated that miR-889-3p directly targets the 3′-UTR region of SON. Lastly, we observed that inhibiting SON could facilitate the browning of rabbit preadipocytes. In conclusion, our findings suggest that miR-889-3p facilitates the browning process of white adipocyte precursors by specifically targeting the SON gene. [ABSTRACT FROM AUTHOR]

This article traces how medieval texts written in English and French adopt the link between human language and bear roaring to inscribe bears into the poetic landscape. I place this discussion in the context of archaeological evidence, which reveals a steady increase in the presence of ursids in England after the Norman conquest, before which they were extinct, and culminating in the bear fighting arenas of early modern England. I show that works such as the Femina, the Roman de Renart and the Ovide moralisé depict ursids in ways that reflect a foundational interest in the ties that bind the act of writing with a zoopoetical reflection on animality. In this way, bears in literary texts are not limited by their extinction from a landscape, or conversely by their presence as commodities. Rather, literary bears may be read in dialogue with a complex and evolving historical and archaeological record. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Cultural Studies / Kültür Araştırmaları Dergisi is the property of Journal of Cultural Studies / Kultur Arastirmalari Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

No one can dispute the significant influence of Sinitic Buddhism in East Asia, but Korean Buddhists were also unquestionably close to the center of the development of different schools of Buddhism in mainland China, particularly in the Jiangnan region, which had historically drawn monks from the peninsula. This article will briefly cover the historical transnational Buddhist interactions between Korea and China, with an emphasis on doctrinal Buddhism, the significance of Ŭisang and Ǔich'ǒn, and the influence of Hangzhou's Buddhist intellectual advancements. Even though the article's main focus is on doctrinal contacts, we will also briefly discuss Chan Buddhism in China and how it influenced the texts and techniques of the Korean Sŏn (Zen) monk Chinul (1158–1210), who made an effort to integrate the doctrinal and meditational traditions, as did Ǔich'ǒn. This process of idea-cross-fertilization led to the Tripitaka Koreana, the largest collection of Buddhist texts in East Asia, created by Buddhists during the Koryŏ dynasty (918–1392), which is discussed below. This will aid in our understanding of these transnational exchanges and highlight the fact that Koreans were not only absorbing new ideas as they emerged in China, but they were also influencing them. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Language & Literature Studies is the property of Turkiye Dil ve Edebiyat Dernegi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Zhu‐Tokita‐Takenouchi‐Kim (ZTTK, OMIM 617140) syndrome is a severe multisystem developmental disorder characterized by intellectual disability, developmental delay, cortical malformations, epilepsy, visual problems, musculoskeletal abnormalities, and congenital malformations. ZTTK syndrome is caused by a heterozygous pathogenic variant of the SON gene (NM_138927) at chromosome 21q22.1. The purpose of this study was to investigate the pathogenesis of a 6‐month‐old Chinese child who exhibited global developmental delay, muscle weakness, malnutrition, weight loss, and strabismus, brain abnormality, immunological system abnormalities. Methods: The little girl was tested for medical exome sequencing (MES) and mtDNA sequencing in trio. And, the mutation was validated by Sanger sequencing. Results: A novel de novo frameshift variant, c.1845_1870del26 (p.G616Sfs*61), in the SON gene was found in the proband. Conclusion: We described a 6‐month‐old Chinese child with global developmental delay caused by pathogenic de novo mutation c.1845_1870del26 (p.G616Sfs*61) in the SON. Apart from a founder mutation, we reviewed the phenotypic abnormalities and genotypes in 79 individuals. The data showed that global developmental delay is accompanied by other system disorders. Our findings expanded the mutational spectrum of ZTTK syndrome and provide genetic counseling of baby with global developmental delay. [ABSTRACT FROM AUTHOR]

Zhu-Tokita-Takenouchi-Kim syndrome is a multisystem disorder resulting from haploinsufficiency in the SON gene, which is characterized by developmental delay/intellectual disability, seizures, facial dysmorphism, short stature, and congenital malformations, primarily in the central nervous system, along with ophthalmic, dental, pulmonary, cardiologic, renal, gastrointestinal, and musculoskeletal anomalies. In this study, we describe the first Colombian patient with ZTT harboring a novel mutation that has not been previously reported and review the clinical and molecular features of previously reported patients in the literature. [ABSTRACT FROM AUTHOR]

In this paper, we further develop the notion of the 'sensory home'. We reveal how gustatory, olfactory and sonic experiences shape where and when one feels 'at home'. We draw on a qualitative, longitudinal methodology to explore how low-income Puerto Ricans experienced domestic tastescapes, smellscapes and soundscapes during the first 12 months after Hurricane Maria in 2017. We first show how the sensory home is made with familiar and routine sensory experiences, and unmade by intrusive and unfamiliar tastes, smells and sounds. Second, the sensory home is temporally dynamic as it is constituted by changing processes taking place on multiple scales and by multiple actors – particularly the state and neighbourhood. Thus, un/making the sensory home is inherently political as it is tied to state-citizen power relations – our third contribution. Finally, in disasters people asymmetrically recover not just economically or materially, but as we show, sensorially. [ABSTRACT FROM AUTHOR]

Copyright of Social Anthropology / Anthropologie Sociale is the property of Berghahn Books and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Zhu–Tokita–Takenouchi–Kim syndrome is a multisystem disorder resulting from haploinsufficiency in the SON gene, which is characterized by developmental delay/intellectual disability, seizures, facial dysmorphism, short stature, and congenital malformations, primarily in the central nervous system, along with ophthalmic, dental, pulmonary, cardiologic, renal, gastrointestinal, and musculoskeletal anomalies. In this study, we describe the first Colombian patient with ZTT harboring a novel mutation that has not been previously reported and review the clinical and molecular features of previously reported patients in the literature.

In this very personal text, Marie Chouinard talks about her work, from the very beginning, with voice, breath, sound and, above all, with and through silence. She discusses her choreographic work, «M», which premiered on January 26, 2023 at the Grand Théâtre de Québec, particularly from the point of view of her relationship to sound and music. She talks about her collaboration with composer Louis Dufort, with whom she has worked for 25 years, and the special role he played in «M», which incorporates a “vocal score” by the choreographer. [ABSTRACT FROM AUTHOR]

Copyright of Orbis Tertius is the property of Universidad Nacional de La Plata and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This article investigates how sons in the scholar-literati class in late imperial China promoted their mothers as Confucian exemplars. From the position and perspectives of a son, what were the strategies of promotion, and how might these strategies be related to the different social roles Confucian literati were expected to play? Through an examination of sons' written tributes to their mothers in a variety of biographical and commemorative genres, this article argues that these writings show an increasing enthusiasm to promote mothers as Confucian exemplars during this historical period, and that this phenomenon was related to these writers' endeavors to promote themselves as members of the Confucian cultural elite and to raise their own social profiles. Some of these writings also expose sons' potential conflicting obligations in the context of polygamy, in which the mother's status as wife or concubine of the father could complicate the son's commemoration and raise questions about the proper ways in which the son could show respect to his different mothers (whether formal mother or concubine mother), especially when his own birth mother happened to be his father's concubine. [ABSTRACT FROM AUTHOR]

Dr. Sayyed Abdolbaghi Modarres, the son of the martyr Ayatollah Sayyed Hasan Modarres, was born in Isfahan on Thursday, January 12th, 19051. He completed his primary education in this city. Having been elected as a leading mujtahid in the second term of the National Assembly in 1911, his late father emigrated to Tehran (Khajeh Nouri, 1978, pp. 3-7). He took his eldest son Sayyed Ismail with him and sent his other children to the town of Esfeh2 to stay with their mother temporarily. They were supposed to join their father after he found a suitable place in Tehran. However, due to the death of their mother, the children were forced to leave for Tehran earlier. After coming to Tehran, Sayyed Abdolbaghi received his primary education in this city and studied religious sciences in the Sepahsalar college, which was entrusted to Ayatollah Modarres by order of Ahmad Shah on July 18, 1925 (Modarresi, 1987, p. 164). He continued studying there until the age of 13.

A father trying to save the relationship with his son involves deceiving him.

The fifth generation (5G) of mobile networks connects people, things, data, applications, transport systems, and cities in smart networked communication environments. With the growth in the amount of generated data, the number of wirelessly connected machines, traffic types, and associated requirements, ensuring high-quality mobile connectivity becomes incredibly difficult for technology suppliers. Mobile operators and network vendors enrolling in 5G face far more rapid demands than any technology before, and at the same time need to ensure efficiency and reliability in the network operations. In fact, intelligent forecasting and decision-making strategies are several of the centerpieces of current artificial intelligence research in various domains. Due to its strong fitting ability, machine learning is seen to have great potential to be employed to solve telecommunication networks' optimization problems that range from the design of hardware elements to network self-optimization. This paper addresses the question of how to apply artificial intelligence to 5G radio access control and feed ML techniques with radio characteristic-based automatic data collection to achieve ML-based evaluation of 5G performance. The proposed methodology endorses ML tools for the 5G portfolio scenarios requirements assessment and integrates into the mature methods for network performance optimization: self-organizing networks (SON) and minimization of drive tests (MDT). In this context, the proposed treatment guides future network deployments and implementations adopted on a 3GPP standard basis. [ABSTRACT FROM AUTHOR]

In the light of changes in society, relationships and marriages too have changed considerably. Due to the growing professional activity of women, the traditional and often unbalanced role allocation had to undergo a change. It has become increasingly important to find extra-familial facilities which can take care of the children. And an even more immediate problem has been how father and mother could manage with responsibility that the mother, too, can go out to work and can make a career for herself without detriment to the children. In day nurseries or crèches there is sometimes a lack of quantity and quality regarding the caretakers. How can the risks of crèches be reduced? Since boys scarcely ever meet a man in preschool education, they are deemed to have smaller chances than girls. This is the reason why mentally present fathers are so important and beneficial in the family during the child’s first years. From birth and during the various stages in life, the father exerts significant, varying, and distinctive functions for the mental development of his children that differ from those of their mother. He has a major importance for identification and triangulation and has quite different functions for the mental development of girls and boys. Fatherlessness is a significant risk factor. The differing gender-related consequences for girls and boys are serious and can have an adverse effect on the whole life. [ABSTRACT FROM AUTHOR]

Nous développerons l'hypothèse que si la violence est inhérente à la vie c'est parce qu'à l'origine, la psyché du sujet est soumise à une violence irreprésentable. Cette violence est à l'origine une violence sensorielle dont on peut établir qu'elle a comme paradigme la violence sonore en raison des deux principales caractéristiques du sensoriel sonore : l'absence de limite et l'absence de concrétude. Le mythe du dieu Pan nous aide à penser dans quelle mesure la violence sonore, lorsqu'elle n'est pas intégrée, se situe à l'origine des mouvements de violence agie. Les actes violents de Pan sont à entendre comme la répétition de la violence sonore subie précocement du fait de l'abandon maternel. Ainsi, le mythe de Pan nous invite à penser qu'à l'aube de la vie, le sonore doit être intégré afin que l'espace psychique de l'enfant puisse se former. Mais à ce moment-là, c'est à l'environnement de lui prêter sa propre enveloppe sonore afin d'endiguer la violence inévitable du sonore. La rencontre de Pan avec le musical lui permettra de métaboliser quelque peu son expérience sonore et de ne pas sombrer complètement dans la folie. We will develop the hypothesis that if violence is inherent to life, to that which constitutes our humanity, it is because primarily the psyche of the subject is subjected to an unspeakable violence. This violence is in its origins, a sensory violence, which acts on the subject before the latter has recourse to it. This violence of sensations about which it can be established that it has sound violence as its paradigm precisely because of the two main characteristics of sound: the absence of limits and the absence of concreteness. The myth of the god Pan helps us to think about what extent sound violence, when it is not integrated, is at the origin of the movements of perpetrated violence. In the myth, the original sound violence can be interpreted as an early traumatic element (before the acquisition of verbal language) that will repeat itself over and over again in an attempt to be assimilated. In other words, Pan's violent acts are to be understood as the repetition of the sonic violence suffered early on as a result of maternal abandonment. It is with sound that the god Pan sows terror and panic in the armies and the herds. Thus, the myth of Pan invites us to consider that at the dawn of life, sound must be integrated (assimilated) so that the psychic space of the child can be formed. But at that point in life, the young child does not yet possess the necessary capacities for representation and it is then up to the environment to lend him its own sound envelope in order to stem the inevitable sonic violence (this is what Pan lacks). His encounter with music will allow him to metabolize his sound experience somewhat and not to sink completely into madness. [ABSTRACT FROM AUTHOR]

Throughout his treatise on the Holy Spirit, St. Basil of Caesarea argues that the Holy Spirit must be given the same honor and glory as the Father and the Son. The baptismal formula (Matthew 20:19) is crucial to his argument, for it reveals that the Holy Spirit is inseparable from the Father and the Son. The Spirit participates with the Father and the Son in all divine activity, from the creation of angelic beings to the final judgment. To demonstrate the divine status of the Holy Spirit, St. Basil uses more than four hundred quotations, allusions, echoes, and parallels from the New Testament text. For St. Basil, the place and role of the Epistle to the Colossians in his treatise On the Holy Spirit proves that the argument of demonstration is a deep reflection of New Testament theology. [ABSTRACT FROM AUTHOR]

This article is an attempt to explore the difficult relationship between two artists – father and son in Wacław Berent's novel Próchno. In the first part of the article, I focus on presenting the biography of Wacław Berent before explaining the structure of the novel. The problematic analysis of the chosen topic begins with the presentation of one of the main characters of Próchno, Władysław Borowski. Władysław is an example of a character whose relationship with his father has a significant impact on the quality of both life and decisions made. Due to their completely different attitude to life, both father and son become interesting subjects for interpretation. Berent's novel describes the hardships of artists struggling with decadent reality. [ABSTRACT FROM AUTHOR]

The intent of this study, The Son in his relationship with the Father. For a new humanity consists in highlighting the founding aspect of the Christological mystery, which lies in the structure of Crist's subjectivity of being and behaving as the Son of God in vital relationship with the Father both at the divine and human levels. This constitutes its unmistakable and absolute identity, which is indicated by the New Testament texts, by some magisterial pronouncements and by the thought of St. Thomas Aquinas. From human participation in divine filiation derives a new anthropological and moral vision of human existence and living. [ABSTRACT FROM AUTHOR]

Résumé : Dans le déploiement de sa théorie musicale, Schopenhauer réalise que la lumière génère du son. Toutefois, il admet que ce son n’émet aucune détonation ou ne produit pas de choc. Il est donc statique. Il convient cependant, de comprendre que le son est une compression de l’air ou une onde de pression de l’air, en s’opposant à la mécanisation de la musique. C’est ce qui justifie son refus des correspondances établies entre les couleurs et le son, entre musique et couleurs. À l’en croire, il est impossible d’établir des analogies entre les sept couleurs et les sept notes de la gamme diatonique. Car selon lui, les sons n’engendrent pas de couleurs. Mais aujourd’hui, cette pratique est récurrente. Elle a permis à certains physiciens d’inventer des instruments électriques pour générer des couleurs au cours de la production musicale. Et si l’œuvre musicale n’est pas génératrice de couleurs, elle possède certaines caractéristiques scientifiques. Celles-ci font qu’elle est indissociable aux sciences telles que la mathématique, la physique et l’astronomie.

Résumé : Le mensonge est un antivaleur. Mais dans la communication il se fait délibérément pour plusieurs raisons : pour valoriser, pour dissimiler des émotions, pour la haine, pour éviter une conséquence et parfois pour le plaisir ou pour faire plaisir. Il peut soulever des sentiments ou d’émotions comme des mystères et des vérités qui peuvent entrainer la fascination et la répulsion. Il s’avère que la pérennité de mensonge dans la communication influence le comportement en sanctions ou en récompenses. Ce qui se distingue par le codage, l’analyse et l’organisation des données fournies par l’environnement. L’individu apprend par l’observation et imitation des manières de communiquer avec son environnement ou avec l’autre. L’environnement peut influencer le comportement de l’individu dans la communication qui impact à son tour. Cela peut se manifester dans la politique, l’entreprise et dans la société humaine en général. Depuis l’enfance jusqu’à l’âge adulte, il existe des mensonges qui ne peuvent causer du tort à personne et ceux qui sont dangereux à l’individu.

Background: Vemurafenib (VEM) was a licensed drug for the treatment of skin melanoma and is available only in the market as oral tablets prescribed in huge doses (1920 mg/day). One reason for the high dose is vemurafenib's low oral bioavailability. Methods: VEM-lipid complex (DLC) was predicted based on Conquest and Mercury programs and prepared using the solvent evaporation method using the lipid (phosphatidylethanolamine). DLC was subjected to characterization (FT-IR, Raman spectroscopy, DSC, TGA, P-XRD, and FESEM) to confirm complexation. DLC was used to prepare solid in oil nanodispersion (DLC-SON) and subjected to in vitro, ex vivo, and in vivo evaluation in comparison to our recently prepared conventional SON (VEM-SON) and DLC-control. Results: Conquest and Mercury predict the availability of intermolecular hydrogen bonding between VEM and phosphatidylethanolamine (PE). All characterization tests of DLC ensure the complexation of the drug with PE. Ex vivo studies showed that the drug in DLC-SON has significantly (P Conclusion: The novel lipid complex for VEM prepared using PE as a lipid and enclosed in SON showed higher anticancer activity and topical permeation as well as sustained delivery and good retention time in the dermis that localize the drug in a sufficient concentration to eliminate early diagnosed skin melanoma.

Complex, multistep biochemical reactions that routinely take place in our cells require high concentrations of enzymes, substrates, and other structural components to proceed efficiently and typically require chemical environments that can inhibit other reactions in their immediate vicinity. Eukaryotic cells solve these problems by restricting such reactions into diffusion‐restricted compartments within the cell called organelles that can be separated from their environment by a lipid membrane, or into membrane‐less compartments that form through liquid–liquid phase separation (LLPS). One of the most easily noticeable and the earliest discovered organelle is the nucleus, which harbors the genetic material in cells where transcription by RNA polymerases produces most of the messenger RNAs and a plethora of noncoding RNAs, which in turn are required for translation of mRNAs in the cytoplasm. The interior of the nucleus is not a uniform soup of biomolecules and rather consists of a variety of membrane‐less bodies, such as the nucleolus, nuclear speckles (NS), paraspeckles, Cajal bodies, histone locus bodies, and more. In this review, we will focus on NS with an emphasis on recent developments including our own findings about the formation of NS by two large IDR‐rich proteins SON and SRRM2. [ABSTRACT FROM AUTHOR]

Pancreatic ductal adenocarcinoma (PDAC) develops via dysplastic changes in the epithelia graded as low‐ and high‐grade with accumulation of molecular alterations. Constitutive activation of mitogen‐activated protein kinase (MAPK) contributed by attenuation of DUSP6 plays a key role in sustaining PDAC. Active MAPK induces various molecules that function as effectors to sustain PDAC. AURKA and SON are downstream effectors that contribute substantially to the proliferation and survival of PDAC cells and are potentially useful as therapeutic targets. Active MAPK also promote microRNAs that modulate the proliferation of PDAC cells and are useful as diagnostic markers. Familial pancreatic cancer kindreds in Japan show various germline mutations supposed to increase a pancreatic cancer risk. Intraductal papillary mucinous neoplasms (IPMNs) consist of dilated ducts lined by papillary neoplastic epithelia of various shapes and varying grades of atypia. Various papillae of IPMNs are classified into four subtypes that are associated with clinicopathological features, including patient prognosis. GNAS is a specific driver gene for the development of IPMN through gain‐of‐function mutations. Tracing of molecular alterations has elucidated the mechanism of progression of IPMN from dysplasia to carcinoma, as well as one type of papillae. Intraductal tubulopapillary neoplasms belong to a distinct class of pancreatic neoplasms. [ABSTRACT FROM AUTHOR]