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A comprehensive review of the social entrepreneurship literature on social entrepreneurship's success in solving social challenges despite significant resource and capacity deficits raises questions, particularly regarding how capacities should be built to ensure long-term social and economic impact. Using the theory of organizational learning, this study analyzes the link between team exploratory and exploitative learning on social entrepreneurship orientation. The cross-sectional examination of 473 social enterprises in Ghana verifies our predictions regarding positive connections between the variables. The findings demonstrate that team exploratory learning has a stronger positive impact on social entrepreneurship orientation than team exploitative learning. From a managerial standpoint, Chief Executive Officers (CEOs) of social enterprises can demonstrate greater use of team exploratory and exploitative learning by devising exercises that push their teams outside of their comfort zones to actively engage in internal and external interactive discourse on team learning to substantially impact their social entrepreneurship orientation. From the ambidextrous perspective of social enterprises, circumventing the notable "failure" and "success" traps that occur with excessive exploration and exploitation respectively, demands a balance between the two for long-term impact on social entrepreneurship orientation. This study delves into the differentially positive function of team exploratory and exploitative learning on social entrepreneurship orientation, with the goal of overcoming the resource/capability bottleneck and boosting social market performance., Author(s): Emmanuel Mensah Horsey [sup.1] [sup.2] , Xiaofan Song [sup.1] , Shuliang Zhao [sup.1] , Xiaobao Peng [sup.1] Author Affiliations: (1) grid.59053.3a, 0000000121679639, School of Public Affairs, University of Science [...]

Objective: This study aimed to explore a kind of food with low glycemic index (GI) and SDS serial products. Methods: Using highland barley powder as raw material. The optimal enzymolysis conditions were determined by single factor test and response surface test. The hypoglycemic activity of α-glucosidase and α-amylase in vitro was evaluated. Results: The content of slow digestion starch in the enzymolysis highland barley powder reached the highest of 16.55%, under the control of the conditions of 60 U/g β-amylase, 3.5 h enzymolysis time, 51 ℃ enzymolysis temperature, and 1∶12 (g/mL) solid to liquid ratio. Meanwhile, the modified highland barley powder had a certain inhibitory effect on α-glucosidase and α-amylase. The highest inhibitory rates of the modified highland barley powder on α-glucosidase and α-amylase were 71.39% and 48.32%, respectively. Conclusion: Under the control of the optimal enzymatic hydrolysis conditions, the content of slow digestible starch in the enzymatic modified highland barley powder was significantly increased.

Dielectric capacitors are widely used in aerospace, power systems, and other fields. Working environments with ever‐increasing temperatures pose a new challenge to energy storage performance. Polyetherimide (PEI) has gained extensive research for its good high‐temperature properties. In order to further improve its energy storage performance at high temperatures, many researchers have worked on PEI all‐organic composites doping with molecular semiconductors. Previous studies generally only considered the effect of introduced deep traps on macroscopic properties such as electrical conductivity, electrical breakdown, and energy storage performance. It has been shown that only qualitative analyses can be performed from the perspective of charge trapping, and it is difficult to obtain quantitative results. Therefore, this work proposes to study the macroscopic properties of polymer dielectrics by combining charge trapping with molecular displacement. A comprehensive conduction‐breakdown‐energy storage model was established to explain the influence mechanism of molecular semiconductors on the improved energy storage performance of PEI composites at high temperatures. The molecular semiconductor fillers increase the coefficient of friction between molecular chains, which restricts the movement of molecular chains and also limits charge hopping. Therefore, the dielectrics have higher breakdown strengths and smaller conduction losses, which synergistically enhance the energy storage performance. [ABSTRACT FROM AUTHOR]

Prior studies demonstrate the role of resources in shaping a firm’s entrepreneurial orientation from the resource-based view. We expand this line of research by theorising and testing the impact of resource bricolage on entrepreneurial orientation. Based on the data of 295 start-ups, we find that when start-ups face resource constraints, the strategy of resource bricolage has a significant positive effect on entrepreneurial orientation, and the relationship is positively moderated by top management team (TMT) heterogeneity. Meanwhile, the relationship is negatively moderated by TMT behavioral integration. The results are expected to provide theoretical guidance for start-ups to overcome resource constraints and achieve smooth survival and growth.

Deposition of aggregated amyloid beta (Aβ) protein is considered to be a major causative factor that is associated with the development of oxidative stress and neuroinflammation in the pathogenesis of Alzheimer's disease (AD). Selenium nanoparticles (SeNPs) have been experimentally using for treatment of neurological disease due to their low toxicity, high bioavailability, and multiple bioactivities. This study was conducted to investigate the protective effects of biogenic SeNPs by Lactobacillus casei ATCC 393 against Aβ25–35-induced toxicity in PC12 cells and its association with oxidative stress and inflammation. The results showed that SeNPs had no cytotoxicity on PC12 cells. Moreover, SeNPs entered cells through cellular endocytosis, which effectively attenuated Aβ25–35-induced toxicity in PC12 cells. In addition, compared with Aβ25–35 model group, SeNP pretreatment significantly enhanced the antioxidant capacity, inhibited the overproduction of reactive oxygen species (ROS), effectively regulated the inflammatory response, decreased the activity of acetylcholinesterase, significantly reduced the expression level of caspase-1 and the ratio of Bcl-2/Bax, and upregulated the expression level of p53. Furthermore, compared with Aβ25–35 model group, SeNPs effectively promoted the phosphorylation of Akt and cAMP-response element-binding protein (CREB), and upregulated the expression level of brain-derived neurotrophic factor (BDNF). In addition, the Akt inhibitor (AKT inhibitor VIII, AKTi-1/2) could reverse the protective effects of SeNPs on PC12 cells. The Akt agonist (SC79) had a similar effect on PC12 cells as that of SeNPs. Overall, this study demonstrated that biogenic SeNPs can effectively alleviate the Aβ25–35-induced toxicity in PC12 cells via Akt/CREB/BDNF signaling pathway. [ABSTRACT FROM AUTHOR]