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857 results on '"Souza, Júlio"'

9. IgM antibody responses against Plasmodium antigens in neotropical primates in the Brazilian Atlantic Forest

Author

de Assis, Gabriela Maíra Pereira, de Alvarenga, Denise Anete Madureira, Braga e Souza, Luisa, Sánchez-Arcila, Juan Camilo, Fernandes e Silva, Eduardo, de Pina-Costa, Anielle, Gonçalves, Gustavo Henrique Pereira, Souza, Júlio César de Junior, Nunes, Ana Julia Dutra, Pissinatti, Alcides, Moreira, Silvia Bahadian, de Menezes Torres, Leticia, Costa, Helena Lott, da Penha Tinoco, Herlandes, do Socorro Pereira, Valéria, da Silva Soares, Irene, de Sousa, Taís Nóbrega, Ntumngia, Francis Babila, Adams, John H, Kano, Flora Satiko, Hirano, Zelinda Maria Braga, Pratt-Riccio, Lilian Rose, Daniel-Ribeiro, Cláudio Tadeu, Ferreira, Joseli Oliveira, Carvalho, Luzia Helena, and de Brito, Cristiana Ferreira Alves

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Vector-Borne Diseases, Biotechnology, Infectious Diseases, Rare Diseases, Malaria, Infection, Good Health and Well Being, malaria, Plasmodium, IgM antibodies, neotropical primates, Atlantic forest, pre-erythrocytic stage antigen, erythrocytic stage antigens, Biochemistry and Cell Biology, Microbiology, Medical microbiology
Abstract

IntroductionZoonotic transmission is a challenge for the control and elimination of malaria. It has been recorded in the Atlantic Forest, outside the Amazon which is the endemic region in Brazil. However, only very few studies have assessed the antibody response, especially of IgM antibodies, in Neotropical primates (NP). Therefore, in order to contribute to a better understanding of the immune response in different hosts and facilitate the identification of potential reservoirs, in this study, naturally acquired IgM antibody responses against Plasmodium antigens were evaluated, for the first time, in NP from the Atlantic Forest.MethodsThe study was carried out using 154 NP samples from three different areas of the Atlantic Forest. IgM antibodies against peptides of the circumsporozoite protein (CSP) from different Plasmodium species and different erythrocytic stage antigens were detected by ELISA.ResultsFifty-nine percent of NP had IgM antibodies against at least one CSP peptide and 87% against at least one Plasmodium vivax erythrocytic stage antigen. Levels of antibodies against PvAMA-1 were the highest compared to the other antigens. All families of NP showed IgM antibodies against CSP peptides, and, most strikingly, against erythrocytic stage antigens. Generalized linear models demonstrated that IgM positivity against PvCSP and PvAMA-1 was associated with PCR-detectable blood-stage malaria infection and the host being free-living. Interestingly, animals with IgM against both PvCSP and PvAMA-1 were 4.7 times more likely to be PCR positive than animals that did not have IgM for these two antigens simultaneously.DiscussionIgM antibodies against different Plasmodium spp. antigens are present in NP from the Atlantic Forest. High seroprevalence and antibody levels against blood-stage antigens were observed, which had a significant association with molecular evidence of infection. IgM antibodies against CSP and AMA-1 may be used as a potential marker for the identification of NP infected with Plasmodium, which are reservoirs of malaria in the Brazilian Atlantic Forest.

Published
2023

18. Use of Decentralized-Learning Methods Applied to Healthcare: A Bibliometric Analysis

Author

Ameijeiras-Rodriguez, Carolina, Rb-Silva, Rita, Diniz, Jose Miguel, Souza, Julio, Freitas, Alberto, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Mikyška, Jiří, editor, de Mulatier, Clélia, editor, Paszynski, Maciej, editor, Krzhizhanovskaya, Valeria V., editor, Dongarra, Jack J., editor, and Sloot, Peter M.A., editor

Published
2023
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19. Smart Wearable Systems for the Remote Monitoring of Venous and Diabetic Foot Ulcers: State of the Art

Author

Souza, Julio, Escadas, Sara, Rodrigues, Daniel, Freitas, Alberto, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Julián, Vicente, editor, Carneiro, João, editor, Alonso, Ricardo S., editor, Chamoso, Pablo, editor, and Novais, Paulo, editor

Published
2023
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37. Towards a Process Reference Model for Clinical Coding

Author

Caballero, Ismael, Souza, Júlio, Lopes, Fernando, Santos, João Vasco, Freitas, Alberto, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Vallecillo, Antonio, editor, Visser, Joost, editor, and Pérez-Castillo, Ricardo, editor

Published
2022
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38. Requirement Specification for a Remote Monitoring System to Support the Management of Vascular Diseases

Author

Escadas, Sara, Souza, Julio, Vieira, Ana, Conceição, Luís, Sampaio, Sérgio, Freitas, Alberto, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Rocha, Alvaro, editor, Adeli, Hojjat, editor, Dzemyda, Gintautas, editor, and Moreira, Fernando, editor

Published
2022
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44. ANÁLISE DA RELAÇÃO DA UMIDADE RELATIVA DO AR, FOCOS DE CALOR E PRECIPITAÇÃO ACUMULADA NO AMAZONAS

Author

De Lima Filho, Arlindo Almeida, primary, Correa, Bruno Gabriel Santos, additional, De Souza, Júlio César Gonçalves, additional, Vieira, Michael Raphael Soares, additional, Silvestrim, Eneida Guerra, additional, Silvestrim, Fernanda Guerra, additional, De Araújo, Andrea Campos Guerra, additional, and Santana, Genilson Pereira, additional

Published
2024
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50. Defining an Architecture for a Remote Monitoring Platform to Support the Self-management of Vascular Diseases

Author

Vieira, Ana, Carneiro, João, Conceição, Luís, Martins, Constantino, Souza, Julio, Freitas, Alberto, Marreiros, Goreti, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Barbosa, Simone Diniz Junqueira, Editorial Board Member, Chen, Phoebe, Editorial Board Member, Cuzzocrea, Alfredo, Editorial Board Member, Du, Xiaoyong, Editorial Board Member, Kara, Orhun, Editorial Board Member, Liu, Ting, Editorial Board Member, Sivalingam, Krishna M., Editorial Board Member, Slezak, Dominik, Editorial Board Member, Washio, Takashi, Editorial Board Member, Yang, Xiaokang, Editorial Board Member, Yuan, Junsong, Editorial Board Member, De La Prieta, Fernando, editor, El Bolock, Alia, editor, Durães, Dalila, editor, Carneiro, João, editor, Lopes, Fernando, editor, and Julian, Vicente, editor

Published
2021
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