Search

Your search keyword '"Specker C"' showing total 643 results
Start Over Author "Specker C"
643 results on '"Specker C"'

5. Characteristics and outcomes of SARS-CoV-2 breakthrough infections among double-vaccinated and triple-vaccinated patients with inflammatory rheumatic diseases

Author

Hasseli-Fräbel, R, Richter, JG, Hoyer, BF, Lorenz, HM, Pfeil, A, Regierer, AC, Schmeiser, T, Strangfeld, A, Voll, RE, Krause, A, Reckert, S, Gräßler, A, Saar, P, Kapelle, A, Backhaus, M, Blank, N, Henes, J, Osiek, S, Knothe, A, Hoese, G, Brandt-Jürgens, J, Maltzahn, A, Specker, C, Müller-Ladner, U, Schulze-Koops, H, Hasseli-Fräbel, R, Richter, JG, Hoyer, BF, Lorenz, HM, Pfeil, A, Regierer, AC, Schmeiser, T, Strangfeld, A, Voll, RE, Krause, A, Reckert, S, Gräßler, A, Saar, P, Kapelle, A, Backhaus, M, Blank, N, Henes, J, Osiek, S, Knothe, A, Hoese, G, Brandt-Jürgens, J, Maltzahn, A, Specker, C, Müller-Ladner, U, and Schulze-Koops, H

Published
2024

6. Impact of Risk Factors on COVID-19 Outcomes in Unvaccinated People With Rheumatic Diseases: A Comparative Analysis of Pandemic Epochs Using the COVID-19 Global Rheumatology Alliance Registry

Author

Yazdany, J, Ware, A, Wallace, Z, Bhana, S, Grainger, R, Hachulla, E, Richez, C, Cacoub, P, Hausmann, J, Liew, J, Sirotich, E, Jacobsohn, L, Strangfeld, A, Mateus, E, Hyrich, K, Gossec, L, Carmona, L, Lawson-Tovey, S, Kearsley-Fleet, L, Schaefer, M, Ribeiro, S, Al-Emadi, S, Hasseli, R, Müller-Ladner, U, Specker, C, Schulze-Koops, H, Bernardes, M, Fraga, V, Rodrigues, A, Sparks, J, Ljung, L, Di Giuseppe, D, Tidblad, L, Wise, L, Duarte-García, A, Ugarte-Gil, M, Colunga-Pedraza, I, Martínez-Martínez, M, Alpizar-Rodriguez, D, Xavier, R, Isnardi, C, Pera, M, Pons-Estel, G, Izadi, Z, Gianfrancesco, M, Carrara, G, Scirè, C, Zanetti, A, Machado, P, Wallace, ZS, Hausmann, JS, Liew, JW, Mateus, EF, Hyrich, KL, Ribeiro, SLE, Fraga, VM, Rodrigues, AM, Sparks, JA, Ugarte-Gil, MF, Colunga-Pedraza, IJ, Martínez-Martínez, MU, Xavier, RM, Isnardi, CA, Gianfrancesco, MA, Scirè, CA, Machado, PM, Yazdany, J, Ware, A, Wallace, Z, Bhana, S, Grainger, R, Hachulla, E, Richez, C, Cacoub, P, Hausmann, J, Liew, J, Sirotich, E, Jacobsohn, L, Strangfeld, A, Mateus, E, Hyrich, K, Gossec, L, Carmona, L, Lawson-Tovey, S, Kearsley-Fleet, L, Schaefer, M, Ribeiro, S, Al-Emadi, S, Hasseli, R, Müller-Ladner, U, Specker, C, Schulze-Koops, H, Bernardes, M, Fraga, V, Rodrigues, A, Sparks, J, Ljung, L, Di Giuseppe, D, Tidblad, L, Wise, L, Duarte-García, A, Ugarte-Gil, M, Colunga-Pedraza, I, Martínez-Martínez, M, Alpizar-Rodriguez, D, Xavier, R, Isnardi, C, Pera, M, Pons-Estel, G, Izadi, Z, Gianfrancesco, M, Carrara, G, Scirè, C, Zanetti, A, Machado, P, Wallace, ZS, Hausmann, JS, Liew, JW, Mateus, EF, Hyrich, KL, Ribeiro, SLE, Fraga, VM, Rodrigues, AM, Sparks, JA, Ugarte-Gil, MF, Colunga-Pedraza, IJ, Martínez-Martínez, MU, Xavier, RM, Isnardi, CA, Gianfrancesco, MA, Scirè, CA, and Machado, PM

Abstract

Objective: Approximately one third of individuals worldwide have not received a COVID-19 vaccine. Although studies have investigated risk factors linked to severe COVID-19 among unvaccinated people with rheumatic diseases (RDs), we know less about whether these factors changed as the pandemic progressed. We aimed to identify risk factors associated with severe COVID-19 in unvaccinated individuals in different pandemic epochs corresponding to major variants of concern. Methods: Patients with RDs and COVID-19 were entered into the COVID-19 Global Rheumatology Alliance Registry between March 2020 and June 2022. An ordinal logistic regression model (not hospitalized, hospitalized, and death) was used with date of COVID-19 diagnosis, age, sex, race and/or ethnicity, comorbidities, RD activity, medications, and the human development index (HDI) as covariates. The main analysis included all unvaccinated patients across COVID-19 pandemic epochs; subanalyses stratified patients according to RD types. Results: Among 19,256 unvaccinated people with RDs and COVID-19, those who were older, male, had more comorbidities, used glucocorticoids, had higher disease activity, or lived in lower HDI regions had worse outcomes across epochs. For those with rheumatoid arthritis, sulfasalazine and B-cell–depleting therapy were associated with worse outcomes, and tumor necrosis factor inhibitors were associated with improved outcomes. In those with connective tissue disease or vasculitis, B-cell–depleting therapy was associated with worse outcomes. Conclusion: Risk factors for severe COVID-19 outcomes were similar throughout pandemic epochs in unvaccinated people with RDs. Ongoing efforts, including vaccination, are needed to reduce COVID-19 severity in this population, particularly in those with medical and social vulnerabilities identified in this study.

Published
2024

21. Früh- und Screeningsprechstunden: Ein notwendiger Weg zur besseren Frühversorgung in der internistischen Rheumatologie?: Rheumatologische Früh- und Screeningsprechstundenmodelle in Deutschland

Author

Benesova, K., Lorenz, H.-M., Lion, V., Voigt, A., Krause, A., Sander, O., Schneider, M., Feuchtenberger, M., Nigg, A., Leipe, J., Briem, S., Tiessen, E., Haas, F., Rihl, M., Meyer-Olson, D., Baraliakos, X., Braun, J., Schwarting, A., Dreher, M., Witte, T., Assmann, G., Hoeper, K., Schmidt, R. E., Bartz-Bazzanella, P., Gaubitz, M., and Specker, C.

Published
2019
Full Text
View/download PDF

26. POS1090 IMPLEMENTATION OF QUALITY STANDARDS FOR HEALTH CARE OF PATIENTS WITH RHEUMATOID ARTHRITIS: FIRST RESULTS FROM THE NATIONAL DATABASE OF THE GERMAN COLLABORATIVE ARTHRITIS CENTRES

Author

Albrecht, K., primary, Thiele, K., additional, Aringer, M., additional, Callhoff, J., additional, Karberg, K., additional, Krueger, K., additional, Lakomek, J., additional, Lorenz, H. M., additional, Rudwaleit, M., additional, Schmale-Grede, R., additional, Schneider, M., additional, Spaethling-Mestekemper, S., additional, Specker, C., additional, Zinke, S., additional, Braun, J., additional, and Kiltz, U., additional

Published
2023
Full Text
View/download PDF

28. Einfluss des adulten Morbus Still (AOSD) auf die Lebensqualität und die Erwerbssituation von diagnostizierten Patienten in Deutschland - Daten aus der PRO-AOSD Erhebung

Author

Blank, N, Andreica, I, Pankow, A, Schmalzing, M, Rech, J, Prothmann, U, Bidilean, C, Tatsis, S, Strunk, J, Kästner, P, Specker, C, Sensse, J, Bestler, D, Eisterhues, C, Henes, J, Bühring, B, Häckel, B, Krusche, M, Sözen, Z, Feist, E, Blank, N, Andreica, I, Pankow, A, Schmalzing, M, Rech, J, Prothmann, U, Bidilean, C, Tatsis, S, Strunk, J, Kästner, P, Specker, C, Sensse, J, Bestler, D, Eisterhues, C, Henes, J, Bühring, B, Häckel, B, Krusche, M, Sözen, Z, and Feist, E

Published
2023

30. Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: Results from the COVID-19 Global Rheumatology Alliance physician registry

Author

Sparks, J, Wallace, Z, Seet, A, Gianfrancesco, M, Izadi, Z, Hyrich, K, Strangfeld, A, Gossec, L, Carmona, L, Mateus, E, Lawson-Tovey, S, Trupin, L, Rush, S, Katz, P, Schmajuk, G, Jacobsohn, L, Wise, L, Gilbert, E, Duarte-Garcia, A, Valenzuela-Almada, M, Pons-Estel, G, Isnardi, C, Berbotto, G, Hsu, T, D'Silva, K, Patel, N, Kearsley-Fleet, L, Schafer, M, Ribeiro, S, Al Emadi, S, Tidblad, L, Scire, C, Raffeiner, B, Thomas, T, Flipo, R, Avouac, J, Seror, R, Bernardes, M, Cunha, M, Hasseli, R, Schulze-Koops, H, Muller-Ladner, U, Specker, C, De Souza, V, Da Mota, L, Gomides, A, Dieude, P, Nikiphorou, E, Kronzer, V, Singh, N, Ugarte-Gil, M, Wallace, B, Akpabio, A, Thomas, R, Bhana, S, Costello, W, Grainger, R, Hausmann, J, Liew, J, Sirotich, E, Sufka, P, Robinson, P, Machado, P, Yazdany, J, Sparks J. A., Wallace Z. S., Seet A. M., Gianfrancesco M. A., Izadi Z., Hyrich K. L., Strangfeld A., Gossec L., Carmona L., Mateus E. F., Lawson-Tovey S., Trupin L., Rush S., Katz P., Schmajuk G., Jacobsohn L., Wise L., Gilbert E. L., Duarte-Garcia A., Valenzuela-Almada M. O., Pons-Estel G. J., Isnardi C. A., Berbotto G. A., Hsu T. Y. -T., D'Silva K. M., Patel N. J., Kearsley-Fleet L., Schafer M., Ribeiro S. L. E., Al Emadi S., Tidblad L., Scire C. A., Raffeiner B., Thomas T., Flipo R. -M., Avouac J., Seror R., Bernardes M., Cunha M. M., Hasseli R., Schulze-Koops H., Muller-Ladner U., Specker C., De Souza V. A., Da Mota L. M. H., Gomides A. P. M., Dieude P., Nikiphorou E., Kronzer V. L., Singh N., Ugarte-Gil M. F., Wallace B., Akpabio A., Thomas R., Bhana S., Costello W., Grainger R., Hausmann J. S., Liew J. W., Sirotich E., Sufka P., Robinson P. C., MacHado P. M., Yazdany J., Sparks, J, Wallace, Z, Seet, A, Gianfrancesco, M, Izadi, Z, Hyrich, K, Strangfeld, A, Gossec, L, Carmona, L, Mateus, E, Lawson-Tovey, S, Trupin, L, Rush, S, Katz, P, Schmajuk, G, Jacobsohn, L, Wise, L, Gilbert, E, Duarte-Garcia, A, Valenzuela-Almada, M, Pons-Estel, G, Isnardi, C, Berbotto, G, Hsu, T, D'Silva, K, Patel, N, Kearsley-Fleet, L, Schafer, M, Ribeiro, S, Al Emadi, S, Tidblad, L, Scire, C, Raffeiner, B, Thomas, T, Flipo, R, Avouac, J, Seror, R, Bernardes, M, Cunha, M, Hasseli, R, Schulze-Koops, H, Muller-Ladner, U, Specker, C, De Souza, V, Da Mota, L, Gomides, A, Dieude, P, Nikiphorou, E, Kronzer, V, Singh, N, Ugarte-Gil, M, Wallace, B, Akpabio, A, Thomas, R, Bhana, S, Costello, W, Grainger, R, Hausmann, J, Liew, J, Sirotich, E, Sufka, P, Robinson, P, Machado, P, Yazdany, J, Sparks J. A., Wallace Z. S., Seet A. M., Gianfrancesco M. A., Izadi Z., Hyrich K. L., Strangfeld A., Gossec L., Carmona L., Mateus E. F., Lawson-Tovey S., Trupin L., Rush S., Katz P., Schmajuk G., Jacobsohn L., Wise L., Gilbert E. L., Duarte-Garcia A., Valenzuela-Almada M. O., Pons-Estel G. J., Isnardi C. A., Berbotto G. A., Hsu T. Y. -T., D'Silva K. M., Patel N. J., Kearsley-Fleet L., Schafer M., Ribeiro S. L. E., Al Emadi S., Tidblad L., Scire C. A., Raffeiner B., Thomas T., Flipo R. -M., Avouac J., Seror R., Bernardes M., Cunha M. M., Hasseli R., Schulze-Koops H., Muller-Ladner U., Specker C., De Souza V. A., Da Mota L. M. H., Gomides A. P. M., Dieude P., Nikiphorou E., Kronzer V. L., Singh N., Ugarte-Gil M. F., Wallace B., Akpabio A., Thomas R., Bhana S., Costello W., Grainger R., Hausmann J. S., Liew J. W., Sirotich E., Sufka P., Robinson P. C., MacHado P. M., and Yazdany J.

Abstract

Objective To investigate baseline use of biologic or targeted synthetic (b/ts) disease-modifying antirheumatic drugs (DMARDs) and COVID-19 outcomes in rheumatoid arthritis (RA). Methods We analysed the COVID-19 Global Rheumatology Alliance physician registry (from 24 March 2020 to 12 April 2021). We investigated b/tsDMARD use for RA at the clinical onset of COVID-19 (baseline): abatacept (ABA), rituximab (RTX), Janus kinase inhibitors (JAKi), interleukin 6 inhibitors (IL-6i) or tumour necrosis factor inhibitors (TNFi, reference group). The ordinal COVID-19 severity outcome was (1) no hospitalisation, (2) hospitalisation without oxygen, (3) hospitalisation with oxygen/ventilation or (4) death. We used ordinal logistic regression to estimate the OR (odds of being one level higher on the ordinal outcome) for each drug class compared with TNFi, adjusting for potential baseline confounders. Results Of 2869 people with RA (mean age 56.7 years, 80.8% female) on b/tsDMARD at the onset of COVID-19, there were 237 on ABA, 364 on RTX, 317 on IL-6i, 563 on JAKi and 1388 on TNFi. Overall, 613 (21%) were hospitalised and 157 (5.5%) died. RTX (OR 4.15, 95% CI 3.16 to 5.44) and JAKi (OR 2.06, 95% CI 1.60 to 2.65) were each associated with worse COVID-19 severity compared with TNFi. There were no associations between ABA or IL6i and COVID-19 severity. Conclusions People with RA treated with RTX or JAKi had worse COVID-19 severity than those on TNFi. The strong association of RTX and JAKi use with poor COVID-19 outcomes highlights prioritisation of risk mitigation strategies for these people.

Published
2021

31. Diagnostische Kriterien

Author

Michels, H., Häfner, R., Köhler, L., Zeidler, H., Herzer, P., Burmester, G. R., Genth, E., Gromnica-Ihle, E., Specker, C., Schneider, M., Vaith, P., Peter, H. H., Gross, W. L., Manger, B., Keitel, W., Weseloh, G., Swoboda, B., Raspe, H. H., Häntzschel, H., Ringe, J. D., Dreher, R., and Deutsche Gesellschaft für Rheumatologie e.V.

Published
2007
Full Text
View/download PDF

32. Medikamentöse Therapie

Author

Bolten, W., Krüger, K., Kaiser, H., Keysser, M., Genth, E., Häntzschel, H., Ehlert, A., Wald, A., Kladny, B., Specker, C., Uhlemann, C., Gromnica-Ihle, E., Reinhold-Keller, E., Hein, G., Neeck, G., Michels, H., Nüsslein, H., Schwartz, H., Braun, J., Wollenhaupt, J., Ringe, J. D., Schneider, M., Schwartz-Eywill, M., Oelzner, O., Herzer, P., Keel, P., Dreher, R., Wassenberg, S., Wollina, U., Keitel, W., Rüther, W., Vorbrüggen, W., Zenz, M., Pantel, M., Keysser, G., Fischer-Betz, R., and Deutsche Gesellschaft für Rheumatologie e.V.

Published
2007
Full Text
View/download PDF

35. Europäische Versorgungsstandards für Menschen mit rheumatoider Arthritis: Übersetzung und Kommentierung der von der EULAR unterstützten Vorschläge des eumusc.net durch eine Task Force von DGRh und VRA mit Unterstützung der Deutschen Rheuma-Liga

Author

Braun, J., Krause, A., Aringer, M., Burmester, G., Bessler, F., Engel, J.-M., Faubel, U., Fischer-Betz, R., Genth, E., Gromnica-Ihle, E., Hellmich, B., Kötter, I., Krüger, K., Lakomek, J., Lorenz, H.-M., Manger, B., Märker-Hermann, E., Minden, K., Müller-Ladner, U., Rautenstrauch, J., Rehart, S., Riemekasten, G., Rudwaleit, M., Rüther, W., Schett, G., Schuch, F., Schulze-Koops, H., Specker, C., Wassenberg, S., Wiek, D., Zink, A., and Schneider, M.

Published
2016
Full Text
View/download PDF

36. Brauchen wir noch klinische Studien in der Rheumatologie?

Author

Henkemeier, U., Alten, R., Bannert, B., Baraliakos, X., Behrens, F., Heldmann, F., Kiltz, U., Köhm, M., König, R., Leipe, J., Müller-Ladner, U., Rech, J., Riechers, E., Rubbert-Roth, A., Schmidt, R.E., Schulze-Koops, H., Specker, C., Tausche, A.-K., Wassenberg, S., Witt, M., Witte, T., Zernicke, J., and Burkhardt, H.

Published
2016
Full Text
View/download PDF

37. Regionale kooperative Rheumazentren

Author

Gundelach, B. and Specker, C.

Subjects
Versorgungsforschung, Patient Care Team, Registerstudien, Interdisciplinary cooperation, Interprofessional Relations, Kerndokumentation, Rheumatological care, Register studies, Core documentation, Interdisziplinäre Zusammenarbeit, Rheumatology, Germany, Rheumatic Diseases, Leitthema, Health services research, Humans, Rheumatologische Versorgung, Forecasting
Abstract

Die regionalen kooperativen Rheumazentren haben sich in den letzten 25 Jahren deutschlandweit als „Katalysatoren“ zur Verbesserung der rheumatologischen Versorgung auf vielfältigen Ebenen etabliert. Sie haben mit Kampagnen und vielen Aktivitäten die Sichtbarkeit des Fachgebietes gemeinsam mit rheumatologischen Bündnispartnern gefördert und auf wissenschaftlicher Seite gemeinsam mit dem Deutschen Rheumaforschungszentrum zur Verbesserung der rheumatologischen Versorgungsforschung in Deutschland beigetragen. Die regionalen kooperativen Rheumazentren sind in ihrem Zusammenschluss als Arbeitsgemeinschaft der Deutschen Gesellschaft für Rheumatologie inzwischen zu einem wichtigen Partner im „Netzwerk Rheumatologie“ geworden, und sie stellen sich auch in Zukunft neuen Aufgaben zur weiteren Verbesserung der rheumatologischen Versorgung in Deutschland.

Published
2020

39. Durchbruchinfektionen bei vollständig geimpften Patienten mit entzündlich-rheumatischen Erkrankungen - Daten aus dem COVID19-Rheuma.de-Register

Author

Hasseli, R, Hoyer, BF, Huppke, L, Lorenz, HM, Pfeil, A, Regierer, A, Richter, J, Schmeiser, T, Strangfeld, A, Voll, R, Krause, A, Schulze-Koops, H, Specker, C, Müller-Ladner, U, Hasseli, R, Hoyer, BF, Huppke, L, Lorenz, HM, Pfeil, A, Regierer, A, Richter, J, Schmeiser, T, Strangfeld, A, Voll, R, Krause, A, Schulze-Koops, H, Specker, C, and Müller-Ladner, U

Published
2022

50. OP0179 CHARACTERISTICS AND OUTCOMES OF SARS-CoV-2 BREAKTHROUGH INFECTIONS AMONG DOUBLE AND TRIPLE VACCINATED PATIENTS WITH INFLAMMATORY RHEUMATIC DISEASES

Author

Hasseli, R., primary, Hoyer, B. F., additional, Lorenz, H. M., additional, Pfeil, A., additional, Regierer, A., additional, Richter, J., additional, Schmeiser, T., additional, Strangfeld, A., additional, Krause, A., additional, Voll, R., additional, Schulze-Koops, H., additional, Müller-Ladner, U., additional, and Specker, C., additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results