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1,107 results on '"Spinelli, L."'

3. No Difference in Muscle Basal Oxygenation in a Bedridden Population Pre and Post Rehabilitation

Author

Re, R., Scano, A., Tomba, A., Pirovano, I., Caserta, A., Spinelli, L., Contini, D., Cubeddu, R., Panella, L., Torricelli, A., Crusio, Wim E., Series Editor, Dong, Haidong, Series Editor, Radeke, Heinfried H., Series Editor, Rezaei, Nima, Series Editor, Steinlein, Ortrud, Series Editor, Xiao, Junjie, Series Editor, Scholkmann, Felix, editor, LaManna, Joseph, editor, and Wolf, Ursula, editor

Published
2023
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7. Brazilian palygorskite as an alternative to commercial adsorbents for methylene blue: A discussion about composition, morphology and pore profile

Author

Ministerio de Ciencia e Innovación (España), Figueiredo, V. V., Vianna, E. L. F., Lima, Bruno S., Jesus, T. C. L., García-Villén, Fátima, Bertolino, L. C., Spinelli, L. S., Viseras, César, Ministerio de Ciencia e Innovación (España), Figueiredo, V. V., Vianna, E. L. F., Lima, Bruno S., Jesus, T. C. L., García-Villén, Fátima, Bertolino, L. C., Spinelli, L. S., and Viseras, César

Abstract

Palygorskite has attracted particular attention as a specialized adsorbent due to its high specific surface area, porous texture and abundant surface groups, but its processing for commercial products makes the resulting material more expensive. In this scope, the aim of this work is to evaluate the potential of Brazilian naturally occurring palygorskite samples with low processing degree as an alternative to commercial palygorskites adsorbents for methylene blue, evaluating samples with different compositions, morphologies and microporous profiles. Materials were characterized using FTIR, X-ray diffraction, X-ray fluorescence, scanning electron microscopy, and surface area analysis (BET method). The Brazilian ones were processed in bar and disk mills and passed through a # 325 mesh sieve system. All samples showed common palygorskite X-ray diffraction patterns and specific surface area ranging from 100 to 147 m/g. The application of clay samples was investigated for the adsorption of methylene blue (MB) dye, and the influence time of adsorption, initial dye concentration and adsorbent dosage were evaluated. The methylene blue adsorption was best described by the pseudo-second order model. The adsorption kinetics of methylene blue by palygorskite conforms to the pseudo-second-order model (R = 0,9997). The maximum removal capacity for methylene blue was determined to be 694 (±36.53) mg/g. Additionally, the Freundlich model demonstrated the most favorable mathematical fit. Adsorption capacities varied between 49 and 150 mg/g for 300 mg/L MB solutions, with noteworthy performance exhibited by Brazilian samples, achieving up to twice the adsorption compared to their commercial counterparts, despite possessing lower specific surface areas. The presence of two distinct pore modes, centered at 25 and 45 Å, proved pivotal in the sample with the highest adsorption capacity, reaching adsorption equilibrium at 40 min.

Published
2024

12. Long-term Effects of Octreotide on Liver Volume in Patients With Polycystic Kidney and Liver Disease

Author

Pisani, A., Sabbatini, M., Ruggenenti, P., Remuzzi, G., Visciano, B., Amicone, M., Dipietro, R., Mozzillo, G., Riccio, E., Rossano, R., Spinelli, L., Santangelo, M., Rubis, N., Diadei, O., Calini, W., Villa, A., Sabatella, M., Ene-Iordache, B., Carminati, S., Martinetti, D., Giuliano, G.A., Perna, A., Liuzzi, R., Remuzzi, A., Imbriaco, M., Prinster, A., Altiero, M., Boccardo, P., Peracchi, S., Pisani, Antonio, Sabbatini, Massimo, Imbriaco, Massimo, Riccio, Eleonora, Rubis, Nadia, Prinster, Anna, Perna, Annalisa, Liuzzi, Raffaele, Spinelli, Letizia, Santangelo, Michele, Remuzzi, Giuseppe, and Ruggenenti, Piero

Published
2016
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17. MAGNETIC FIELD SENSOR BASED ON FERROFLUID AND SIDEPOLISHED MACRO-BENDING PLASTIC OPTICAL FIBER SENSOR.

Author

Sousa, A. D., Morgan, V. G., Spinelli, L. S., Allil, R. C. S., and Werneck, M. M.

Subjects
FIBER optical sensors, OPTICAL fiber detectors, PLASTIC optical fibers, MAGNETIC fields, MAGNETIC sensors, MAGNETOELECTRIC effect
Abstract

In this work, a magnetic field sensor based on plastic optical fiber was built. The operation of the sensor exploits the magnetoelectric effect of a ferrofluid. Both the optical sensor and the ferrofluid were manufactured and properly characterized. The integration of both demonstrates the presence of the magnetoelectric effect, and, consequently, the operation of the sensor. [ABSTRACT FROM AUTHOR]

Published
2023

22. Aggressive behavior, cognitive impairment, and depressive symptoms in elderly subjects

Author

Margari F, Sicolo M, Spinelli L, Mastroianni F, Pastore A, Craig F, and Petruzzelli MG

Subjects
Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
Abstract

Francesco Margari,1 Michele Sicolo,1 Lucia Spinelli,1 Franco Mastroianni,2 Adriana Pastore,1 Francesco Craig,3 Maria Giuseppina Petruzzelli31Psychiatry Unit, Department of Neuroscience and Sense Organs, Hospital Polyclinic of Bari, University of Bari “Aldo Moro”, 2Geriatrics Unit, Hospital “Miulli”, Acquaviva delle Fonti; 3Child Neuropsychiatry Unit, Department of Neuroscience and Sense Organs, University of Bari “Aldo Moro,” Bari, ItalyAbstract: Patients with dementia often have neuropsychiatric symptoms. The objective of this study was to evaluate the relationship between neuropsychiatric symptoms and progressive cognitive decline by assessing cognitive impairment, depressive symptoms, and aggressive behavior in a sample of elderly subjects. The study sample consisted of 201 subjects admitted to nursing homes. For the purpose of the present study each subject was evaluated using the Mini-Mental State Examination, the Geriatric Depression Scale, and the Modified Overt Aggression Scale. The results show that aggressive behavior and depressive symptoms are associated with progressive cognitive decline in elderly subjects. Early assessment of these conditions can promote rational therapeutic strategies that may improve the quality of life and delay institutionalization for elderly patients.Keywords: neuropsychiatric symptoms, dementia, behavioral and psychological syndromes of dementia (BPSD), progressive cognitive decline

Published
2012

25. Assessment of muscular sustained fatigue: a TD-NIRS and sEMG study

Author

Re, R., Scano, A., Pirovano, I., Manunza, M. E., Spinelli, L., Contini, D., and Torricelli, A.

Subjects
surgical procedures, operative, EMG, NIRS, muscle, TD-NIRS, technology, industry, and agriculture, sustained, fatigue, equipment and supplies, complex mixtures, neoplasms
Abstract

We assess the muscular fatigue during sustained exercises with both sEMG and TD-NIRS. We found that during the "slow" phase of TD-NIRS signal, the best fatigue biomarkers are: MF, O2Hb, HHb and SO2.

Published
2021

35. Nondestructive determination of ripening in melon fruit using timeresolved spectroscopy.

Author

Vanoli, M., Cortellino, G., Picchi, V., Buccheri, M., Grassi, M., Lovati, F., Marinoni, L., Levoni, P., Torricelli, A., and Spinelli, L.

Subjects
FRUIT ripening, REFLECTANCE spectroscopy, ABSORPTION coefficients, SPECTROMETRY, MELONS, ORANGES, FRUIT skins
Abstract

The aim of this work was to explore the feasibility of timeresolved reflectance spectroscopy (TRS) in determining the ripening degree and the quality of orangefleshed melons. Sixty 'Honey Moon' melons were measured by TRS in the 5401064 nm range and classified as less (LeM), medium (MeM), and more (MoM) mature according to increasing values of µa540. MoM fruit showed yellower peel color, slightly more orange pulp, higher juiciness and higher carotenoid contents than LeM ones. MoM fruit also showed higher internal ethylene concentration and lower firmness than LeM ones, even if the differences were not significant. The µa540 was positively related to internal ethylene, carotenoid accumulation, and juiciness, indicating that µa540 was linked to different ripening processes in melons. However, the relationship between µa540 and total carotenoid content was not as high as expected due to the low variability of pulp color and of carotenoid content. Changes in flesh color toward a more orange shade were accompanied by increased juiciness and ethylene production and by carotenoid accumulation, while changes in peel color were associated with changes in flesh firmness and juiciness. In conclusion, the absorption coefficient measured at 540 nm (µa540) by TRS could be used to sort melons in different ripening degrees; however, its applicability will need to be evaluated on a larger number of fruits and on other varieties. [ABSTRACT FROM AUTHOR]

Published
2023
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36. Cerebral oxygenation and blood flow in term infants during postnatal transition: BabyLux project

Author

De Carli, A, Andresen, B, Giovannella, M, Durduran, T, Contini, D, Spinelli, L, Weigel, U, Passera, S, Pesenti, N, Mosca, F, Torricelli, A, Fumagalli, M, Greisen, G, De Carli A., Andresen B., Giovannella M., Durduran T., Contini D., Spinelli L., Weigel U. M., Passera S., Pesenti N., Mosca F., Torricelli A., Fumagalli M., Greisen G., De Carli, A, Andresen, B, Giovannella, M, Durduran, T, Contini, D, Spinelli, L, Weigel, U, Passera, S, Pesenti, N, Mosca, F, Torricelli, A, Fumagalli, M, Greisen, G, De Carli A., Andresen B., Giovannella M., Durduran T., Contini D., Spinelli L., Weigel U. M., Passera S., Pesenti N., Mosca F., Torricelli A., Fumagalli M., and Greisen G.

Abstract

Objectives A new device that combines, for the first time, two photonic technologies (time-resolved near-infrared spectroscopy and diffuse correlation spectroscopy) was provided and tested within the BabyLux project. Aim was to validate the expected changes in cerebral oxygenation and blood flow. Methods A pulse oximeter and the BabyLux device were held in place (right hand/wrist and frontoparietal region, respectively) for 10 min after birth in healthy term infants delivered by elective caesarean section. Pulse oximeter saturation (SpO 2), cerebral tissue oxygen saturation (StO 2) and blood flow index (BFI) were measured over time. Tissue oxygen extraction (TOE) and cerebral metabolic rate of oxygen index (CMRO 2 I) were calculated. Results Thirty infants were enrolled in two centres. After validity check of data, 23% of infants were excluded from TOE and CMRO 2 I calculation due to missing data. As expected, SpO 2 (estimate 3.05 %/min; 95% CI 2.78 to 3.31 %/min) and StO 2 (estimate 3.95 %/min; 95% CI 3.63 to 4.27 %/min) increased in the first 10 min after birth, whereas BFI (estimate-2.84×10-9 cm 2/s/min; 95% CI-2.50×10-9 to-3.24×10-9 cm 2/s/min) and TOE (estimate-0.78 %/min; 95% CI-1.12 to-0.45 %/min) decreased. Surprisingly, CMRO 2 I decreased (estimate-7.94×10-8/min; 95% CI-6.26×10-8 to-9.62×10-8/min). Conclusions Brain oxygenation and BFI during transition were successfully and simultaneously obtained by the BabyLux device; no adverse effects were recorded, and the BabyLux device did not limit the standard care. The preliminary results from clinical application of the BabyLux device are encouraging in terms of safety and feasibility; they are consistent with previous reports on brain oxygenation during transition, although the interpretation of the decreasing CMRO 2 I remains open. Trial registration number NCT02815618.

Published
2019

37. Assessment of network module identification across complex diseases

Author

Choobdar, S, Ahsen, M, Crawford, J, Tomasoni, M, Fang, T, Lamparter, D, Lin, J, Hescott, B, Hu, X, Mercer, J, Natoli, T, Narayan, R, Aicheler, F, Amoroso, N, Arenas, A, Azhagesan, K, Baker, A, Banf, M, Batzoglou, S, Baudot, A, Bellotti, R, Bergmann, S, Boroevich, K, Brun, C, Cai, S, Caldera, M, Calderone, A, Cesareni, G, Chen, W, Chichester, C, Cowen, L, Cui, H, Dao, P, De Domenico, M, Dhroso, A, Didier, G, Divine, M, del Sol, A, Feng, X, Flores-Canales, J, Fortunato, S, Gitter, A, Gorska, A, Guan, Y, Guenoche, A, Gomez, S, Hamza, H, Hartmann, A, He, S, Heijs, A, Heinrich, J, Hu, Y, Huang, X, Hughitt, V, Jeon, M, Jeub, L, Johnson, N, Joo, K, Joung, I, Jung, S, Kalko, S, Kamola, P, Kang, J, Kaveelerdpotjana, B, Kim, M, Kim, Y, Kohlbacher, O, Korkin, D, Krzysztof, K, Kunji, K, Kutalik, Z, Lage, K, Lang-Brown, S, Le, T, Lee, J, Lee, S, Li, D, Li, J, Liu, L, Loizou, A, Luo, Z, Lysenko, A, Ma, T, Mall, R, Marbach, D, Mattia, T, Medvedovic, M, Menche, J, Micarelli, E, Monaco, A, Muller, F, Narykov, O, Norman, T, Park, S, Perfetto, L, Perrin, D, Pirro, S, Przytycka, T, Qian, X, Raman, K, Ramazzotti, D, Ramsahai, E, Ravindran, B, Rennert, P, Saez-Rodriguez, J, Scharfe, C, Sharan, R, Shi, N, Shin, W, Shu, H, Sinha, H, Slonim, D, Spinelli, L, Srinivasan, S, Subramanian, A, Suver, C, Szklarczyk, D, Tangaro, S, Thiagarajan, S, Tichit, L, Tiede, T, Tripathi, B, Tsherniak, A, Tsunoda, T, Turei, D, Ullah, E, Vahedi, G, Valdeolivas, A, Vivek, J, von Mering, C, Waagmeester, A, Wang, B, Wang, Y, Weir, B, White, S, Winkler, S, Xu, K, Xu, T, Yan, C, Yang, L, Yu, K, Yu, X, Zaffaroni, G, Zaslavskiy, M, Zeng, T, Zhang, J, Zhang, L, Zhang, W, Zhang, X, Zhou, X, Zhou, J, Zhu, H, Zhu, J, Zuccon, G, Stolovitzky, G, Choobdar S., Ahsen M. E., Crawford J., Tomasoni M., Fang T., Lamparter D., Lin J., Hescott B., Hu X., Mercer J., Natoli T., Narayan R., Aicheler F., Amoroso N., Arenas A., Azhagesan K., Baker A., Banf M., Batzoglou S., Baudot A., Bellotti R., Bergmann S., Boroevich K. A., Brun C., Cai S., Caldera M., Calderone A., Cesareni G., Chen W., Chichester C., Cowen L., Cui H., Dao P., De Domenico M., Dhroso A., Didier G., Divine M., del Sol A., Feng X., Flores-Canales J. C., Fortunato S., Gitter A., Gorska A., Guan Y., Guenoche A., Gomez S., Hamza H., Hartmann A., He S., Heijs A., Heinrich J., Hu Y., Huang X., Hughitt V. K., Jeon M., Jeub L., Johnson N. T., Joo K., Joung I. S., Jung S., Kalko S. G., Kamola P. J., Kang J., Kaveelerdpotjana B., Kim M., Kim Y. -A., Kohlbacher O., Korkin D., Krzysztof K., Kunji K., Kutalik Z., Lage K., Lang-Brown S., Le T. D., Lee J., Lee S., Li D., Li J., Liu L., Loizou A., Luo Z., Lysenko A., Ma T., Mall R., Marbach D., Mattia T., Medvedovic M., Menche J., Micarelli E., Monaco A., Muller F., Narykov O., Norman T., Park S., Perfetto L., Perrin D., Pirro S., Przytycka T. M., Qian X., Raman K., Ramazzotti D., Ramsahai E., Ravindran B., Rennert P., Saez-Rodriguez J., Scharfe C., Sharan R., Shi N., Shin W., Shu H., Sinha H., Slonim D. K., Spinelli L., Srinivasan S., Subramanian A., Suver C., Szklarczyk D., Tangaro S., Thiagarajan S., Tichit L., Tiede T., Tripathi B., Tsherniak A., Tsunoda T., Turei D., Ullah E., Vahedi G., Valdeolivas A., Vivek J., von Mering C., Waagmeester A., Wang B., Wang Y., Weir B. A., White S., Winkler S., Xu K., Xu T., Yan C., Yang L., Yu K., Yu X., Zaffaroni G., Zaslavskiy M., Zeng T., Zhang J. D., Zhang L., Zhang W., Zhang X., Zhang J., Zhou X., Zhou J., Zhu H., Zhu J., Zuccon G., Stolovitzky G., Cowen L. J., Choobdar, S, Ahsen, M, Crawford, J, Tomasoni, M, Fang, T, Lamparter, D, Lin, J, Hescott, B, Hu, X, Mercer, J, Natoli, T, Narayan, R, Aicheler, F, Amoroso, N, Arenas, A, Azhagesan, K, Baker, A, Banf, M, Batzoglou, S, Baudot, A, Bellotti, R, Bergmann, S, Boroevich, K, Brun, C, Cai, S, Caldera, M, Calderone, A, Cesareni, G, Chen, W, Chichester, C, Cowen, L, Cui, H, Dao, P, De Domenico, M, Dhroso, A, Didier, G, Divine, M, del Sol, A, Feng, X, Flores-Canales, J, Fortunato, S, Gitter, A, Gorska, A, Guan, Y, Guenoche, A, Gomez, S, Hamza, H, Hartmann, A, He, S, Heijs, A, Heinrich, J, Hu, Y, Huang, X, Hughitt, V, Jeon, M, Jeub, L, Johnson, N, Joo, K, Joung, I, Jung, S, Kalko, S, Kamola, P, Kang, J, Kaveelerdpotjana, B, Kim, M, Kim, Y, Kohlbacher, O, Korkin, D, Krzysztof, K, Kunji, K, Kutalik, Z, Lage, K, Lang-Brown, S, Le, T, Lee, J, Lee, S, Li, D, Li, J, Liu, L, Loizou, A, Luo, Z, Lysenko, A, Ma, T, Mall, R, Marbach, D, Mattia, T, Medvedovic, M, Menche, J, Micarelli, E, Monaco, A, Muller, F, Narykov, O, Norman, T, Park, S, Perfetto, L, Perrin, D, Pirro, S, Przytycka, T, Qian, X, Raman, K, Ramazzotti, D, Ramsahai, E, Ravindran, B, Rennert, P, Saez-Rodriguez, J, Scharfe, C, Sharan, R, Shi, N, Shin, W, Shu, H, Sinha, H, Slonim, D, Spinelli, L, Srinivasan, S, Subramanian, A, Suver, C, Szklarczyk, D, Tangaro, S, Thiagarajan, S, Tichit, L, Tiede, T, Tripathi, B, Tsherniak, A, Tsunoda, T, Turei, D, Ullah, E, Vahedi, G, Valdeolivas, A, Vivek, J, von Mering, C, Waagmeester, A, Wang, B, Wang, Y, Weir, B, White, S, Winkler, S, Xu, K, Xu, T, Yan, C, Yang, L, Yu, K, Yu, X, Zaffaroni, G, Zaslavskiy, M, Zeng, T, Zhang, J, Zhang, L, Zhang, W, Zhang, X, Zhou, X, Zhou, J, Zhu, H, Zhu, J, Zuccon, G, Stolovitzky, G, Choobdar S., Ahsen M. E., Crawford J., Tomasoni M., Fang T., Lamparter D., Lin J., Hescott B., Hu X., Mercer J., Natoli T., Narayan R., Aicheler F., Amoroso N., Arenas A., Azhagesan K., Baker A., Banf M., Batzoglou S., Baudot A., Bellotti R., Bergmann S., Boroevich K. A., Brun C., Cai S., Caldera M., Calderone A., Cesareni G., Chen W., Chichester C., Cowen L., Cui H., Dao P., De Domenico M., Dhroso A., Didier G., Divine M., del Sol A., Feng X., Flores-Canales J. C., Fortunato S., Gitter A., Gorska A., Guan Y., Guenoche A., Gomez S., Hamza H., Hartmann A., He S., Heijs A., Heinrich J., Hu Y., Huang X., Hughitt V. K., Jeon M., Jeub L., Johnson N. T., Joo K., Joung I. S., Jung S., Kalko S. G., Kamola P. J., Kang J., Kaveelerdpotjana B., Kim M., Kim Y. -A., Kohlbacher O., Korkin D., Krzysztof K., Kunji K., Kutalik Z., Lage K., Lang-Brown S., Le T. D., Lee J., Lee S., Li D., Li J., Liu L., Loizou A., Luo Z., Lysenko A., Ma T., Mall R., Marbach D., Mattia T., Medvedovic M., Menche J., Micarelli E., Monaco A., Muller F., Narykov O., Norman T., Park S., Perfetto L., Perrin D., Pirro S., Przytycka T. M., Qian X., Raman K., Ramazzotti D., Ramsahai E., Ravindran B., Rennert P., Saez-Rodriguez J., Scharfe C., Sharan R., Shi N., Shin W., Shu H., Sinha H., Slonim D. K., Spinelli L., Srinivasan S., Subramanian A., Suver C., Szklarczyk D., Tangaro S., Thiagarajan S., Tichit L., Tiede T., Tripathi B., Tsherniak A., Tsunoda T., Turei D., Ullah E., Vahedi G., Valdeolivas A., Vivek J., von Mering C., Waagmeester A., Wang B., Wang Y., Weir B. A., White S., Winkler S., Xu K., Xu T., Yan C., Yang L., Yu K., Yu X., Zaffaroni G., Zaslavskiy M., Zeng T., Zhang J. D., Zhang L., Zhang W., Zhang X., Zhang J., Zhou X., Zhou J., Zhu H., Zhu J., Zuccon G., Stolovitzky G., and Cowen L. J.

Abstract

Many bioinformatics methods have been proposed for reducing the complexity of large gene or protein networks into relevant subnetworks or modules. Yet, how such methods compare to each other in terms of their ability to identify disease-relevant modules in different types of network remains poorly understood. We launched the ‘Disease Module Identification DREAM Challenge’, an open competition to comprehensively assess module identification methods across diverse protein–protein interaction, signaling, gene co-expression, homology and cancer-gene networks. Predicted network modules were tested for association with complex traits and diseases using a unique collection of 180 genome-wide association studies. Our robust assessment of 75 module identification methods reveals top-performing algorithms, which recover complementary trait-associated modules. We find that most of these modules correspond to core disease-relevant pathways, which often comprise therapeutic targets. This community challenge establishes biologically interpretable benchmarks, tools and guidelines for molecular network analysis to study human disease biology.

Published
2019

43. PH-0499 SABR as a treatment option for HCC patients: efficacy and toxicity profile

Author

Carlevato, R., primary, Chiofalo, V., additional, Spinelli, L., additional, Giglioli, F.R., additional, Carucci, P., additional, Rolle, E., additional, Rizza, G., additional, Faletti, R., additional, Romagnoli, R., additional, Saracco, G.M., additional, Fonio, P., additional, Iorio, G.C., additional, Guarneri, A.S., additional, and Ricardi, U., additional

Published
2021
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44. PD-0915 SABR as a bridge therapy for HCC patients awaiting liver transplant

Author

spinelli, L., primary, Carlevato, R., additional, Chiofalo, V., additional, Gallio, E., additional, Gaia, S., additional, Rizza, G., additional, Faletti, R., additional, Molinaro, L., additional, Papotti, M.G., additional, Romagnoli, R., additional, Saracco, G.M., additional, Fonio, P., additional, Iorio, G.C., additional, Guarneri, A.S., additional, and Ricardi, U., additional

Published
2021
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45. Rehabilitation Monitoring After Bed Rest in Elderly: TD-NIRS and sEMG Preliminary Study

Author

Pirovano, I., Laurini, A., Tomba, A., Scano, A., Re, R., Caserta, A., Spinelli, L., Contini, D., Cubeddu, R., Panella, L., and Torricelli, A.

Subjects
sarcopenia, EMG, NIRS, muscle, TD-NIRS, patients, rehabilitation
Abstract

We report on a preliminary longitudinal study on 21 elderly patients to non-invasively quantify rehabilitation outcomes in skeletal muscle after bed-rest by a combined approach based on TD-NIRS (for hemodynamics) and sEMG (for myoelectric recordings).

Published
2021

47. Layers

Author

Spinelli, L.

Subjects
recording, overlapping, resurfacing, overlaying
Published
2021

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