We investigate magnetic activity properties of 21 stars via medium resolution optical spectra and long-term photometry. Applying synthetic spectrum fitting method, we find that all targets are cool giant or sub-giant stars possessing overall [M/H] abundances between 0 and -0.5. We find that six of these targets exhibit only linear trend in mean brightness, while eight of them clearly shows cyclic mean brightness variation. Remaining seven target appear to exhibit cyclicmean brightness variation, but this cannot be confirmed due to the long timescales of the predicted cycle compared to the current time range of the photometric data. We further determine seasonal photometric periods and compute average photometric period of each target. Analysed sample in this study provides a quantitative representation of a positive linear correlation between the inverse of the rotation period and the cycle period normalised to the rotation period, on the log-log scale. We also observe no correlation between the activity cycle length and the relative surface shear, indicating that the activity cycle must be driven by a parameter rather than the differential rotation. Our analyses show that the relative surface shear is positively correlated with the rotation period and there is a noticeable separation between main sequence stars and our sample. Compared to our sample, the relative surface shear of a main sequence star is larger for a given rotation period. However, dependence of the relative surface shear on the rotation period appears stronger for our sample. Analysis of the current photometric data indicates that the photometric properties of the observed activity cycles in eight targets seem dissimilar to the sunspot cycle.Y, TuBTAK National Observatory [14BRTT150-678, 18BRTT150-1275], I am indebted to Dr. Grzegorz Pojmaski for reducing and providing unpublished ASAS-3N data, which compensate long data gap between published ASAS3 and ASAS-SN data and increase the precision of the main results of this study. I also express my thanks to Dr. Hasan Ali Dal for fruitful discussion on statistical analyses. I acknowledge the anonymous referee for his/her helpful comments and valuable suggestions that have significantly contributed to improve the paper. I further thank TuBTAK National Observatory for a partial support in using RTT150 (Russian-Turkish 1.5-m telescope in Antalya) with project numbers 14BRTT150-678 and 18BRTT150-1275. This research has made use of the SIMBAD database, operated at CDS, Strasbourg, France. This research received no specific grant from any funding agency, commercial, or not-for-profit sectors.