13 results on '"Ssu-Hua Chen"'
Search Results
2. Exploring technological resilience at the country level with patents.
- Author
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Pei-Chun Lee, Ssu-Hua Chen, and Hsin-Ning Su
- Published
- 2018
- Full Text
- View/download PDF
3. Explore users' preference from Facebook fan pages.
- Author
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Li-Chen Cheng, Pin-Yi Li, and Ssu-Hua Chen
- Published
- 2017
- Full Text
- View/download PDF
4. Toward a Better Understanding on Technological Resilience for Sustaining Industrial Development
- Author
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Ssu-Hua Chen, Yi-Siang Lin, Pei-Chun Lee, and Hsin-Ning Su
- Subjects
Strategy and Management ,0502 economics and business ,05 social sciences ,Production (economics) ,Business ,Electrical and Electronic Engineering ,Duration (project management) ,Economic system ,Resilience (network) ,050203 business & management - Abstract
Environmental change and unexpected crises are major threats to industrial development. Industries must build technological resilience to reduce the impact of shocks. Resilience has become a crucial concept for addressing vulnerabilities and developing flexible methods of adapting to crises. This study examined the concept of technological resilience, particularly at the industry level, as well as the factors that may influence technological resilience. Moreover, the relative capability of industries to maintain their production of technological knowledge during disruptive events was examined by analyzing the growth and crises of patenting. This methodology yielded novel insights into technological resilience with multidimensional perspectives. Collaboration reinforces technological resilience by reducing crisis probability and intensity. In addition, high-quality and diversified technological knowledge enhances technological resilience by reducing the probability, intensity, or duration of crises.
- Published
- 2019
5. Exploring technological resilience at the country level with patents
- Author
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Pei Chun Lee, Hsin-Ning Su, and Ssu Hua Chen
- Subjects
Strategy and Management ,media_common.quotation_subject ,05 social sciences ,Interpersonal communication ,Competitor analysis ,Oecd countries ,Management Science and Operations Research ,Country level ,0502 economics and business ,Economics ,Quality (business) ,050207 economics ,Duration (project management) ,Economic system ,Resilience (network) ,050203 business & management ,Diversity (business) ,media_common - Abstract
Resilience is critical to stabilise and reduce shocks and create advantages over competitors in environments with dramatic change and unexpected crises. There is no generally agreed-upon definition of technological resilience, and there is not yet a well-developed theory of technological resilience at the country level. The objective of this paper is to contribute to technological resilience research based on patent indicators by analyzing OECD countries’ technological resilience. This paper provides a framework to analyze the quality of selected patent indicators used for estimating technological crisis. More specifically, four sets of patent indicators, i.e. collaboration, knowledge, diversity, and legal protection, are employed to evaluate technological resilience, which is characterised as crisis probability, intensity, and duration. We found that higher technological coverage leads to higher crisis probability, more original technology leads to higher crisis intensity, and interpersonal colla...
- Published
- 2018
6. Explore users' preference from Facebook fan pages
- Author
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Pin-Yi Li, Li-Chen Cheng, and Ssu-Hua Chen
- Subjects
World Wide Web ,Computer science ,Cyberpsychology ,020204 information systems ,Social media network ,0202 electrical engineering, electronic engineering, information engineering ,Key (cryptography) ,020201 artificial intelligence & image processing ,Social media ,02 engineering and technology ,Crawling ,Recommender system ,Preference - Abstract
The massive amounts of data available on social media platforms become the key source of information related to customer sentiment and opinions for analysis by companies. Facebook is one of the most popular platforms which a firm can take advantage of to establish customer relationships through the use of fan pages. Facebook fan pages contain rich sources of information related to customer relationships. This study proposes a novel recommender system based on analyzing the behavior of fans. The proposed method is able to overcome the limitations of traditional recommender system. Three common measures will be used to evaluate the effectiveness of the proposed method. The experimental data have been obtained by crawling from IMDb fan pages..
- Published
- 2017
7. Ambidexterity of Innovative Capability and Economic Performance
- Author
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Hsin-Ning Su and Ssu-Hua Chen
- Subjects
Country level ,Knowledge base ,business.industry ,InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL ,0502 economics and business ,05 social sciences ,Innovation management ,050207 economics ,Diversification (marketing strategy) ,business ,050203 business & management ,Industrial organization ,Ambidexterity - Abstract
The economic performance of countries is defined as an assessment for a country of its success in global markets related to its knowledge base, innovative capabilities and overall market strength. Technological diversification is considered as one of the factors of economic growth. Therefore, the article investigates the extent to which technological diversification affects economic development and how capabilities approach economic performance of a country. Technological diversification is a phenomenon that extends a firm's technology base into a wide range of technology fields. Whereas previous studies have provided insights into the connection between technological diversification and firms' performance, little is known about the influence of technological diversification on countries' innovative performance and trends. The purpose of the paper is to examine the relationship among technological diversification and economic performance at country level. A heuristic framework for depicting how a country's capability interacts with its economic growth is proposed in this study to contribute to technology and innovation management.
- Published
- 2017
8. SLC41A1, a Na+/Mg2+ exchanger, is downregulated during exercise
- Author
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Hsuan‑Ying Chen, Nicole Hsiung, Alyson Pin‑Tsz Tseng, Fu‑Chou Cheng, Ssu‑Hua Chen, and Hannah Wei
- Subjects
medicine.medical_specialty ,Oncogene ,business.industry ,General Neuroscience ,medicine.medical_treatment ,Transporter ,General Medicine ,Bioinformatics ,Molecular medicine ,General Biochemistry, Genetics and Molecular Biology ,Basal (phylogenetics) ,Endocrinology ,Apoptosis ,Internal medicine ,Gene expression ,Medicine ,General Pharmacology, Toxicology and Pharmaceutics ,Treadmill ,business ,Saline - Abstract
Serum magnesium (Mg) levels are closely controlled through a variety of Mg transporters and ionic channels during physiological conditions. These levels have been shown to increase during exercise. However, the effect of Mg transporter expression during exercise remains to be determined. The purpose of this study was to examine the gene expression of SLC41A1, a Na+/Mg2+ exchanger, during exercise. In the present study, male C57BL/6JNarl mice (n=16, 8 weeks old) were subjected to 3 h forced exercise on a treadmill. The mice in the control and Mg groups were injected with saline and Mg (MgSO4, 90 mg/kg, intraperitoneal), respectively. Blood samples were obtained at three time points: prior to, following and 24 h after exercise. The gene expression levels of SLC41A1 were significantly downregulated to 23.6±4.6 and 12.6±10.2% following exercise in the control and Mg groups, respectively. The expression levels returned to the basal levels 24 h after exercise in the two groups and there was no significant difference found between the two groups. The downregulated role of SLC41A1 expression and its interaction with the Mg status in exercise requires further investigation.
- Published
- 2014
9. Effects of magnesium sulfate on dynamic changes of brain glucose and its metabolites during a short-term forced swimming in gerbils
- Author
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Chien-Pin Lee, Shiu-Min Cheng, Dar-Yu Yang, Fu-Chou Cheng, Mao-Tsun Lin, Ssu-Hua Chen, and Hung-Chuan Pan
- Subjects
Male ,medicine.medical_specialty ,Microdialysis ,Physiology ,medicine.medical_treatment ,Metabolite ,Intraperitoneal injection ,chemistry.chemical_element ,Biology ,Gerbil ,Magnesium Sulfate ,chemistry.chemical_compound ,Physiology (medical) ,Internal medicine ,Pyruvic Acid ,medicine ,Animals ,Orthopedics and Sports Medicine ,Saline ,Swimming ,Brain Chemistry ,Magnesium ,Public Health, Environmental and Occupational Health ,General Medicine ,Neostriatum ,Glucose ,Endocrinology ,chemistry ,Basal (medicine) ,Pyruvic acid ,Energy Metabolism ,Extracellular Space ,Gerbillinae - Abstract
This investigation examined the acute effects of magnesium on the dynamic changes of brain glucose, lactate, pyruvate and magnesium levels in conscious gerbils during forced swimming. Gerbils were pretreated with saline (control group) and magnesium sulfate (90 mg kg(-1), intraperitoneal injection) before a 15 min forced swimming period. The basal levels of glucose, pyruvate, lactate, and magnesium in brain dialysates were 338 +/- 18, 21 +/- 2, 450 +/- 39, and 2.1 +/- 0.1 microM, respectively, with no significant difference between groups. Magnesium levels were found slightly higher (but not significant) in the magnesium-treated group. However, brain glucose and pyruvate levels in the control group decreased to about 50 and 60% of the basal level (P = 0.01) after swimming, respectively. Pretreatment with magnesium sulfate immediately increased glucose levels to about 140% of the basal level, and increased pyruvate levels to about 150% of the basal level during forced swimming (P = 0.01). Both glucose and pyruvate levels returned to the basal level after 30 min of the recovery. The lactate levels of the control group increased to about 160% of the basal level (P = 0.01) during swimming, whereas pretreatment with magnesium sulfate attenuated lactate levels to 130% of the basal level (P = 0.01). Magnesium supplementation may be beneficial because it provides an additional glucose source and may also promote the recovery of energy substrates in the brain during and after forced exercise. In order to achieve optimal physical performance, further investigation as to dosage of magnesium supplementation is needed.
- Published
- 2007
10. SLC41A1, a Na
- Author
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Alyson Pin-Tsz, Tseng, Hannah, Wei, Nicole, Hsiung, Ssu-Hua, Chen, Hsuan-Ying, Chen, and Fu-Chou, Cheng
- Subjects
Articles - Abstract
Serum magnesium (Mg) levels are closely controlled through a variety of Mg transporters and ionic channels during physiological conditions. These levels have been shown to increase during exercise. However, the effect of Mg transporter expression during exercise remains to be determined. The purpose of this study was to examine the gene expression of SLC41A1, a Na+/Mg2+ exchanger, during exercise. In the present study, male C57BL/6JNarl mice (n=16, 8 weeks old) were subjected to 3 h forced exercise on a treadmill. The mice in the control and Mg groups were injected with saline and Mg (MgSO4, 90 mg/kg, intraperitoneal), respectively. Blood samples were obtained at three time points: prior to, following and 24 h after exercise. The gene expression levels of SLC41A1 were significantly downregulated to 23.6±4.6 and 12.6±10.2% following exercise in the control and Mg groups, respectively. The expression levels returned to the basal levels 24 h after exercise in the two groups and there was no significant difference found between the two groups. The downregulated role of SLC41A1 expression and its interaction with the Mg status in exercise requires further investigation.
- Published
- 2014
11. Effects of magnesium sulfate on dynamic changes of brain glucose and its metabolites during a short-term forced swimming in gerbils.
- Author
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Shiu-Min Cheng, Dar-Yu Yang, Chien-Pin Lee, Hung-Chuan Pan, Mao-Tsun Lin, Ssu-Hua Chen, and Fu-Chou Cheng
- Subjects
GLUCOSE ,METABOLITES ,MAGNESIUM group ,GERBILS ,PYRUVATES ,LACTATES - Abstract
This investigation examined the acute effects of magnesium on the dynamic changes of brain glucose, lactate, pyruvate and magnesium levels in conscious gerbils during forced swimming. Gerbils were pretreated with saline (control group) and magnesium sulfate (90 mg kg
−1 , intraperitoneal injection) before a 15 min forced swimming period. The basal levels of glucose, pyruvate, lactate, and magnesium in brain dialysates were 338 ± 18, 21 ± 2, 450 ± 39, and 2.1 ± 0.1 μM, respectively, with no significant difference between groups. Magnesium levels were found slightly higher (but not significant) in the magnesium-treated group. However, brain glucose and pyruvate levels in the control group decreased to about 50 and 60% of the basal level ( P = 0.01) after swimming, respectively. Pretreatment with magnesium sulfate immediately increased glucose levels to about 140% of the basal level, and increased pyruvate levels to about 150% of the basal level during forced swimming ( P = 0.01). Both glucose and pyruvate levels returned to the basal level after 30 min of the recovery. The lactate levels of the control group increased to about 160% of the basal level ( P = 0.01) during swimming, whereas pretreatment with magnesium sulfate attenuated lactate levels to 130% of the basal level ( P = 0.01). Magnesium supplementation may be beneficial because it provides an additional glucose source and may also promote the recovery of energy substrates in the brain during and after forced exercise. In order to achieve optimal physical performance, further investigation as to dosage of magnesium supplementation is needed. [ABSTRACT FROM AUTHOR]- Published
- 2007
- Full Text
- View/download PDF
12. SLC41A1, a Na+ /Mg2+ exchanger, is downregulated during exercise.
- Author
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ALYSON PIN-TSZ TSENG, HANNAH WEI, NICOLE HSIUNG, SSU-HUA CHEN, HSUAN-YING CHEN, and FU-CHOU CHENG
- Subjects
GENE expression ,PHYSIOLOGICAL transport of sodium ,MAGNESIUM ,EXERCISE physiology ,LABORATORY mice - Abstract
Serum magnesium (Mg) levels are closely controlled through a variety of Mg transporters and ionic channels during physiological conditions. These levels have been shown to increase during exercise. However, the effect of Mg transporter expression during exercise remains to be determined. The purpose of this study was to examine the gene expression of SLC41A1, a Na
+ /Mg2+ exchanger, during exercise. In the present study, male C57BL/6JNarl mice (n = 16, 8 weeks old) were subjected to 3 h forced exercise on a treadmill. The mice in the control and Mg groups were injected with saline and Mg (MgSO4 , 90 mg/kg, intraperitoneal), respectively. Blood samples were obtained at three time points: prior to, following and 24 h after exercise. The gene expression levels of SLC41A1 were significantly downregulated to 23.6 ± 4.6 and 12.6 ± 10.2% following exercise in the control and Mg groups, respectively. The expression levels returned to the basal levels 24 h after exercise in the two groups and there was no significant difference found between the two groups. The downregulated role of SLC41A1 expression and its interaction with the Mg status in exercise requires further investigation. [ABSTRACT FROM AUTHOR]- Published
- 2014
- Full Text
- View/download PDF
13. Nattokinase Reduces Brain Infarction, Fibrinogen and Activated Partial Thromboplastin Time against Cerebral Ischemia-Reperfusion Injury.
- Author
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Jiunn-Min Wang, Hsuan-Ying Chen, Shiu-Min Cheng, Ssu-Hua Chen, Lin-Lan Yang, and Fu-Chou Cheng
- Subjects
- *
ANIMAL experimentation , *BLOOD coagulation factors , *CEREBRAL ischemia , *INFARCTION , *RESEARCH methodology , *PROTEOLYTIC enzymes , *REPERFUSION injury , *RESEARCH funding , *RODENTS , *SOYBEAN , *T-test (Statistics) , *TISSUE culture , *PLANT extracts , *DATA analysis software , *DESCRIPTIVE statistics - Abstract
Natto is a traditional Japanese food prepared from fermented soybeans. nattokinase (NK) is considered one of the most active functional ingredients in natto. The present study evaluated the neuroprotective effects of NK in gerbils subjected to focal cerebral ischemia. The gerbils were separated into four groups: control group, ischemic group and two NK groups (4 and 40 mg/day i.g. for 7 days). All gerbils were fed standard chow with or without NK prior to cerebral ischemia. Focal cerebral ischemia was induced by the occlusion of the right common carotid artery and middle cerebral artery for 60 min, followed by reperfusion. Infarct volumes were determined by 2,3,5-triphenyltetrazolium chloride staining. Anti-thrombotic effects of NK, such as fibrinogen, prothrombin time and activated partial thromboplastin time, were also determined. Our data showed that NK significantly reduced infarct volumes by 54-68% (p < 0.01), compared to the ischemic group. Prothrombin time was not significantly different in all groups. However, low dosage NK (4 mg/day) reversed ischemic-induced increase in fibrinogen concentrations and activated partial thromboplastin time. In summary, the data indicated that oral intake of NK for 7 days may alter fibrinolytic activity and provide neuroprotective effects against focal cerebral ischemia in gerbils. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF
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