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2 results on '"Stéphane Charara"'

1. Prostatic Fragment Requiring Endoscopic Management After Prostatic Artery Embolization for Indwelling Bladder Catheter

Author

Jean Alexandre Long, Aurélie Delouche, Christian Sengel, Benedicte Guillaume, D. Poncet, Gilbert Ferretti, Julien Ghelfi, Stéphane Charara, Gaelle Fiard, Université Grenoble Alpes - UFR Médecine (UGA UFRM), Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service central de radiologie et d'imagerie médicale, CHU Grenoble-Hôpital Michallon, Clinique Universitaire de Radiologie et Imagerie Médicale, Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble, Gestes Medico-chirurgicaux Assistés par Ordinateur (TIMC-IMAG-GMCAO), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Centre Hospitalier Universitaire [Grenoble] (CHU), CHU Grenoble, and Pôle d'imagerie

Subjects
Male, medicine.medical_specialty, business.industry, [SDV]Life Sciences [q-bio], Prostatic Hyperplasia, Arteries, Endoscopic management, Prostatic artery embolization, 030218 nuclear medicine & medical imaging, Surgery, Urinary Bladder Neck Obstruction, 03 medical and health sciences, Catheters, Indwelling, 0302 clinical medicine, Text mining, 030220 oncology & carcinogenesis, Humans, Medicine, Radiology, Nuclear Medicine and imaging, Cardiology and Cardiovascular Medicine, business, Indwelling bladder catheter, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018
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2. Predonation Single Kidney Glomerular Filtration Rate in Living Kidney Transplantation to Predict Graft Function and Donor Functional Gain

Author

Bénédicte Janbon, Rachel Tetaz, Nicolas Terrier, Stéphane Charara, Thomas Jouve, Paolo Malvezzi, Johan Noble, Hamza Naciri Bennani, Matthieu Roustit, Diane Giovannini, Jean-Jacques Rambeaud, Gaelle Fiard, Isabelle Gomez, Morgane Heitz, and Lionel Rostaing

Subjects
Adult, Male, medicine.medical_specialty, Urology, Renal function, Transplants, Kidney, Graft function, Single kidney, Living Donors, Medicine, Humans, Transplantation, Homologous, Prospective Studies, Retrospective Studies, Transplantation, business.industry, Living kidney transplantation, Middle Aged, University hospital, Kidney Transplantation, medicine.anatomical_structure, Treatment Outcome, Dimercaptosuccinic acid, Surgery, Female, business, Statistical correlation, medicine.drug, Glomerular Filtration Rate
Abstract

Background The 2 main objectives regarding living kidney transplant are to provide optimal graft function and to ensure the safety of donation. Our study hypothesized that the glomerular filtration rate of a single kidney (skGFR), when transplanted, might predict graft function and that the skGFR of the remaining kidney could predict donor functional gain. Methods A prospective monocentric study was conducted at Grenoble-Alpes University Hospital. Twenty couples of donors and recipients were included. Dimercaptosuccinic acid renal scintigraphy and 51Cr-ethylene-diamine tetra-acetic acid clearance were evaluated predonation to calculate skGFR. All patients had renal function according to 51Cr-ethylene-diamine tetra-acetic acid clearance at 1 year post transplant to assess graft function and donor functional gain. All donors had normal renal function predonation. Results At 1 year post transplant, median glomerular filtration rate of the graft was 50 mL/min/1.73 m2 (range, 46-56 mL/min/1.73 m2) and donor median glomerular filtration rate was 59 mL/min/1.73 m2 (range, 55-74 mL/min/1.73 m2). Median functional gain was 20 mL/min/1.73 m2 (range, 12-22 mL/min/1.73 m2). No statistical correlation was found between skGFR of the transplanted kidney and graft function at 1 year (R2 = 0.096, P = .7). For the donor, functional gain was not associated with predonation skGFR of the remaining kidney (R2 = 0.17, P = .5). A statistical difference was found between donor functional gain (18 [SD, 10] mL/min) and recipient gain (delta between skGFR before and after transplant, 7 [SD, 16] mL/min; P = .02). Conclusion Predonation skGFR of the transplanted kidney had no influence on renal allograft function at 1 year post transplant. Similarly, there was no association between measured skGFR of the remaining kidney and donor functional gain at 1 year.

Published
2019

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