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Your search keyword '"Stam, Anita G.M."' showing total 13 results
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13 results on '"Stam, Anita G.M."'

1. Figure S2 from Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8+ T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma

Author

Rotman, Jossie, primary, Heeren, A. Marijne, primary, Gassama, Awa A., primary, Lougheed, Sinead M., primary, Pocorni, Noëlle, primary, Stam, Anita G.M., primary, Bleeker, Maaike C.G., primary, Zijlmans, Henry J.M.A.A, primary, Mom, Constantijne H., primary, Kenter, Gemma G., primary, Jordanova, Ekaterina S., primary, and de Gruijl, Tanja D., primary

Published
2023
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2. Table S1 from Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8+ T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma

Author

Rotman, Jossie, primary, Heeren, A. Marijne, primary, Gassama, Awa A., primary, Lougheed, Sinead M., primary, Pocorni, Noëlle, primary, Stam, Anita G.M., primary, Bleeker, Maaike C.G., primary, Zijlmans, Henry J.M.A.A, primary, Mom, Constantijne H., primary, Kenter, Gemma G., primary, Jordanova, Ekaterina S., primary, and de Gruijl, Tanja D., primary

Published
2023
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3. Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8+ T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma

Author

Rotman, Jossie, primary, Heeren, A. Marijne, additional, Gassama, Awa A., additional, Lougheed, Sinead M., additional, Pocorni, Noëlle, additional, Stam, Anita G.M., additional, Bleeker, Maaike C.G., additional, Zijlmans, Henry J.M.A.A, additional, Mom, Constantijne H., additional, Kenter, Gemma G., additional, Jordanova, Ekaterina S., additional, and de Gruijl, Tanja D., additional

Published
2020
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4. Irreversible electroporation of locally advanced pancreatic cancer transiently alleviates immune suppression and creates a window for antitumor T cell activation

Author

Scheffer, Hester J., primary, Stam, Anita G.M., additional, Geboers, Bart, additional, Vroomen, Laurien G.P.H., additional, Ruarus, Alette, additional, de Bruijn, Beaunelle, additional, van den Tol, M. Petrousjka, additional, Kazemier, Geert, additional, Meijerink, Martijn R., additional, and de Gruijl, Tanja D., additional

Published
2019
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6. Abstract B138: Single low-dose administration of anti-CTLA-4/tremelimumab at the tumor excision site boosts systemic antitumor immunity in early-stage melanoma patients: Results from a Phase-1 study

Author

Stam, Anita G.M., primary, Pul, Kim M. van, additional, Koster, Bas D., additional, Chondronasiou, Dafni, additional, Lougheed, Sinéad M., additional, Tol, M. Petrousjka van den, additional, Jooss, Karin, additional, Vuylsteke, Ronald J.C.L.M., additional, Eertwegh, Alfons J.M. van den, additional, and Gruijl, Tanja D. de, additional

Published
2016
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8. Priming of PRAME- and WT1-specific CD8+T cells in healthy donors but not in AML patients in complete remission

Author

van den Ancker, Willemijn, primary, Ruben, Jurjen M., additional, Westers, Theresia M., additional, Wulandari, Dewi, additional, Bontkes, Hetty J., additional, Hooijberg, Erik, additional, Stam, Anita G.M., additional, Santegoets, Saskia JAM, additional, Ossenkoppele, Gert J., additional, de Gruijl, Tanja D, additional, and van de Loosdrecht, Arjan, additional

Published
2013
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9. Abstract 5381: Activation and frequency of myeloid subsets in peripheral blood is associated with clinical outcome in prostate cancer patients treated with Prostate GVAX and anti-CTLA4

Author

Stam, Anita G.M., primary, Santegoets, Saskia, additional, Scheper, Rik, additional, Lougheed, Sinéad, additional, Gall, Helen, additional, Jooss, Karin, additional, Sacks, Natalie, additional, Hege, Kristen, additional, Lowy, Israel, additional, Cuillerot, Jean-Marie, additional, Gerritsen, Winald, additional, van den Eertwegh, Alfons, additional, and de Gruijl, Tanja, additional

Published
2012
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10. Abstract 5512: Immune correlates of clinical response and survival in castration-resistant prostate cancer patients treated with prostate GVAX and anti-CTLA4 immunotherapy

Author

Santegoets, Saskia J.A.M., primary, van den Eertwegh, Alfons J.M., additional, Stam, Anita G.M., additional, Scheper, Rik J., additional, Lougheed, Sinéad M., additional, Scholten, Petra E.T., additional, von Blomberg, Mary B.M.E., additional, Gall, Helen, additional, Jooss, Karin, additional, Nguyen, Minh C., additional, Harding, Tom, additional, Sacks, Natalie, additional, Hege, Kristen, additional, Lowy, Israel, additional, Chin, Kevin, additional, Gerritsen, Winald R., additional, and de Gruijl, Tanja D., additional

Published
2011
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11. Abstract B20: Immune vs. clinical response monitoring in patients with metastatic hormone-refractory prostate cancer receiving combined prostate GVAX and anti-CTLA4 immunotherapy

Author

Santegoets, Saskia J.A.M., primary, van den Eertwegh, Alfons J.M., additional, Stam, Anita G.M., additional, Scheper, Rik J., additional, Lougheed, Sinead M., additional, Scholten, Petra E.T., additional, Gall, Helen, additional, Jooss, Karin, additional, Sacks, Natalie, additional, Harding, Thomas C., additional, Hege, Kristen, additional, Lowy, Israel, additional, Gerritsen, Winald R., additional, and de Gruijl, Tanja D., additional

Published
2010
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12. Abstract 2538: Dendritic and T cell functions in patients with metastatic hormone-refractory prostate cancer treated with GVAX immunotherapy for prostate cancer and ipilimumab

Author

Santegoets, Saskia J.A.M., primary, van den Eertwegh, Alfons J.M., additional, Lougheed, Sinead M., additional, Stam, Anita G.M., additional, Gall, Helen, additional, Scholten, Petra E.T., additional, von Blomberg, Mary B.E., additional, Hooijberg, Erik, additional, Jooss, Karin, additional, Sacks, Nathalie, additional, Nguyen, Minh, additional, Harding, Thomas, additional, Hege, Kristen, additional, Lowy, Israel, additional, Gerritsen, Winald R., additional, Scheper, Rik J., additional, and de Gruijl, Tanja D., additional

Published
2008
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13. Priming of PRAME- and WT1-specific CD8+ T cells in healthy donors but not in AML patients in complete remission.

Author

van den Ancker, Willemijn, Ruben, Jurjen M., Westers, Theresia M., Wulandari, Dewi, Bontkes, Hetty J., Hooijberg, Erik, Stam, Anita G.M., Santegoets, Saskia J.A.M., Ossenkoppele, Gert J., de Gruijl, Tanja, and van de Loosdrecht, Arjan

Subjects
LEUKEMIA, ANTIVIRAL agents, T cells, MELANOMA, NEUROENDOCRINE tumors, THERAPEUTICS
Abstract

Active immunotherapy may prevent the relapse of acute myeloid leukemia (AML) by inducing leukemia-specific T cells. Here, we investigated whether Wilms' tumor 1 (WT1) and preferentially expressed antigen in melanoma (PR AME)-specific T cells could be induced upon the priming of healthy donor- and AML patient-derived T cells with HLA-A2-matched, peptide-loaded allogeneic dendritic cells. AML-reactive, tetramer (Tm)-binding and interferon-producing, cytotoxic T lymphocytes specific for PR AME could readily be isolated from healthy individuals and maintained in culture. In this setting, priming efficacy was significantly higher for PR AME than for WT1. The priming of T cells from patient-derived material proved to be near-to-impossible: No leukemia-associated antigen (LAA)-specific T cell could be primed in 4 patients that had recently achieved a complete response (CR), and in only 1 out of 3 patients exhibiting a sustained CR we did observe WT1-specific T cells, though with a low frequency. These findings suggest that the functionality and/or repertoire of T cells differ in healthy subjects and AML patients in CR, and may have repercussions for the implementation of active vaccination approaches against AML. [ABSTRACT FROM AUTHOR]

Published
2013
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