330 results on '"Stambolic, Vuk"'
Search Results
2. Machine learning-enabled cancer diagnostics with widefield polarimetric second-harmonic generation microscopy
3. The PTEN and ATM axis controls the G1/S cell cycle checkpoint and tumorigenesis in HER2-positive breast cancer
4. NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity
5. Opposing effects of NPM1wt and NPM1c mutants on AKT signaling in AML
6. Effect of metformin versus placebo on metabolic factors in the MA.32 randomized breast cancer trial
7. A phase II randomized clinical trial of the effect of metformin versus placebo on progression-free survival in women with metastatic breast cancer receiving standard chemotherapy
8. β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog–Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models
9. grb2 Heterozygosity Rescues Embryonic Lethality but Not Tumorigenesis in pten+/- Mice
10. Fundamental Pathways in Breast Cancer 1: Signaling from the Membrane
11. Early Onset of Neoplasia in the Prostate and Skin of Mice with Tissue-Specific Deletion of PTEN
12. Effect of Metformin Versus Placebo on New Primary Cancers in Canadian Cancer Trials Group MA.32: A Secondary Analysis of a Phase III Randomized Double-Blind Trial in Early Breast Cancer
13. Chk2 Regulates Irradiation-Induced, p53-Mediated Apoptosis in Drosophila
14. Association between BMI, vitamin D, and estrogen levels in postmenopausal women using adjuvant letrozole: a prospective study
15. Restricted Accumulation of Phosphatidylinositol 3-Kinase Products in a Plasmalemmal Subdomain during Fcγ Receptor-Mediated Phagocytosis
16. β-catenin turnover is regulated by Nek10-mediated tyrosine phosphorylation in A549 lung adenocarcinoma cells.
17. Concerted roles of PTEN and ATM in controlling hematopoietic stem cell fitness and dormancy
18. Effects of metformin versus placebo on vitamin B12 metabolism in non-diabetic breast cancer patients in CCTG MA.32
19. Structure and Function of the mTOR Activator Rheb
20. NEK10 tyrosine phosphorylates β-catenin to regulate its cytoplasmic turnover
21. Structure-guided Mutation of the Conserved G3-box Glycine in Rheb Generates a Constitutively Activated Regulator of Mammalian Target of Rapamycin (mTOR)
22. Estrogen controls the survival of BRCA1-deficient cells via a PI3K–NRF2-regulated pathway
23. An Autoinhibited Noncanonical Mechanism of GTP Hydrolysis by Rheb Maintains mTORC1 Homeostasis
24. Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts
25. Effect of Metformin vs Placebo on Weight and Metabolic Factors in NCIC CTG MA.32
26. The Ubiquitin Ligase Nedd4-1 Is Dispensable for the Regulation of PTEN Stability and Localization
27. Obesity and insulin resistance in breast cancer – Chemoprevention strategies with a focus on metformin
28. Effect of Metformin vs Placebo on Invasive Disease–Free Survival in Patients With Breast Cancer
29. Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice
30. Wide-Field Multicontrast Nonlinear Microscopy for Histopathology
31. Evidence for biological effects of metformin in operable breast cancer: biomarker analysis in a pre-operative window of opportunity randomized trial
32. PTEN at 18: Still Growing
33. Regulation of Adipocyte Differentiation by Distinct Subcellular Pools of Protein Kinase B (PKB/Akt)
34. Real-time NMR Study of Guanine Nucleotide Exchange and Activation of RhoA by PDZ-RhoGEF
35. Real-time NMR Study of Three Small GTPases Reveals That Fluorescent 2′(3′)-O-(N-Methylanthraniloyl)-tagged Nucleotides Alter Hydrolysis and Exchange Kinetics
36. Abstract GS1-08: CCTGMA.32, a phase III randomized double-blind placebo controlled adjuvant trial of metformin (MET) vs placebo (PLAC) in early breast cancer (BC): Results of the primary efficacy analysis (clinical trials.gov NCT01101438)
37. Cancer: Precise control of localized signals
38. Regulation of the protein kinase activity of ShaggyZeste-white3 by components of the Wingless pathway in Drosophila cells and embryos.
39. Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study
40. Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents
41. Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice
42. Senescence, Necrosis, and Apoptosis Govern Circulating Cell-free DNA Release Kinetics
43. Precise control of localized signals
44. Cancer Antigen 15-3/Mucin 1 Levels in CCTG MA.32: A Breast Cancer Randomized Trial of Metformin vs Placebo
45. The effect of metformin vs placebo on sex hormones in CCTG MA.32
46. Correction: The Rho Guanine Nucleotide Exchange Factor DRhoGEF2 Is a Genetic Modifier of the PI3K Pathway in Drosophila
47. Functional distinctions of protein kinase B/Akt isoforms defined by their influence on cell migration
48. Localization of Rheb to the endomembrane is critical for its signaling function
49. The conserved PI3′K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila
50. Abstract PS18-25: Concordance of immunohistochemical assays between peri-operative and post-operative breast tumor specimens: A prospective observational study of 18 cases
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