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1. Benchmarking the design of the cryogenics system for the underground argon in DarkSide-20k

Author: Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Blua, S., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cebrian, S., Ruiz, J. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galiński, G., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Jois, S., Kachru, P., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kish, A., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kunzé, P., Kuss, M., Kuźniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peck, A., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Shalamova, V., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wojaczyński, R., Wojcik, M., Wojcik, M. M., Wright, T., Xiao, X., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: DarkSide-20k (DS-20k) is a dark matter detection experiment under construction at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy. It utilises ~100 t of low radioactivity argon from an underground source (UAr) in its inner detector, with half serving as target in a dual-phase time projection chamber (TPC). The UAr cryogenics system must maintain stable thermodynamic conditions throughout the experiment's lifetime of >10 years. Continuous removal of impurities and radon from the UAr is essential for maximising signal yield and mitigating background. We are developing an efficient and powerful cryogenics system with a gas purification loop with a target circulation rate of 1000 slpm. Central to its design is a condenser operated with liquid nitrogen which is paired with a gas heat exchanger cascade, delivering a combined cooling power of >8 kW. Here we present the design choices in view of the DS-20k requirements, in particular the condenser's working principle and the cooling control, and we show test results obtained with a dedicated benchmarking platform at CERN and LNGS. We find that the thermal efficiency of the recirculation loop, defined in terms of nitrogen consumption per argon flow rate, is 95 % and the pressure in the test cryostat can be maintained within $\pm$(0.1-0.2) mbar. We further detail a 5-day cool-down procedure of the test cryostat, maintaining a cooling rate typically within -2 K/h, as required for the DS-20k inner detector. Additionally, we assess the circuit's flow resistance, and the heat transfer capabilities of two heat exchanger geometries for argon phase change, used to provide gas for recirculation. We conclude by discussing how our findings influence the finalisation of the system design, including necessary modifications to meet requirements and ongoing testing activities., Comment: 45 pages, 24 figures
Published: 2024

2. DarkSide-20k sensitivity to light dark matter particles

Author: Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Blua, S., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cebrian, S., Ruiz, J. M. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galiński, G., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Jois, S., Kachru, P., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kunzé, P., Kuss, M., Kuźniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peck, A., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Shalamova, V., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Walczak, M. B., Wang, Y., Wang, H., Westerdale, S., Williams, L., Wojaczyński, R., Wojcik, M., Wojcik, M. M., Wright, T., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: The dual-phase liquid argon time projection chamber is presently one of the leading technologies to search for dark matter particles with masses below 10 GeV/c$^2$. This was demonstrated by the DarkSide-50 experiment with approximately 50 kg of low-radioactivity liquid argon as target material. The next generation experiment DarkSide-20k, currently under construction, will use 1,000 times more argon and is expected to start operation in 2027. Based on the DarkSide-50 experience, here we assess the DarkSide-20k sensitivity to models predicting light dark matter particles, including Weakly Interacting Massive Particles (WIMPs) and sub-GeV/c$^2$ particles interacting with electrons in argon atoms. With one year of data, a sensitivity improvement to dark matter interaction cross-sections by at least one order of magnitude with respect to DarkSide-50 is expected for all these models. A sensitivity to WIMP--nucleon interaction cross-sections below $1\times10^{-42}$ cm$^2$ is achievable for WIMP masses above 800 MeV/c$^2$. With 10 years exposure, the neutrino fog can be reached for WIMP masses around 5 GeV/c$^2$., Comment: submitted to Nature Communications
Published: 2024

3. A new hybrid gadolinium nanoparticles-loaded polymeric material for neutron detection in rare event searches

Author: Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cavallo, D., Cebrian, S., Ruiz, J. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galinski, G., Gallina, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peddis, D., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Sadashivajois, S., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Slimani, S., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Tonazzo, A., Torres-Lara, S., Tosi, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Vicini, S., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wojaczynski, R., Wojcik, M. M., Wojcik, M., Wright, T., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: Experiments aimed at direct searches for WIMP dark matter require highly effective reduction of backgrounds and control of any residual radioactive contamination. In particular, neutrons interacting with atomic nuclei represent an important class of backgrounds due to the expected similarity of a WIMP-nucleon interaction, so that such experiments often feature a dedicated neutron detector surrounding the active target volume. In the context of the development of DarkSide-20k detector at INFN Gran Sasso National Laboratory (LNGS), several R&D projects were conceived and developed for the creation of a new hybrid material rich in both hydrogen and gadolinium nuclei to be employed as an essential element of the neutron detector. Thanks to its very high cross-section for neutron capture, gadolinium is one of the most widely used elements in neutron detectors, while the hydrogen-rich material is instrumental in efficiently moderating the neutrons. In this paper results from one of the R&Ds are presented. In this effort the new hybrid material was obtained as a poly(methyl methacrylate) (PMMA) matrix, loaded with gadolinium oxide in the form of nanoparticles. We describe its realization, including all phases of design, purification, construction, characterization, and determination of mechanical properties of the new material.
Published: 2024
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4. Directionality of nuclear recoils in a liquid argon time projection chamber

Author: Collaboration, The DarkSide-20k, Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Corona, M. Atzori, Ave, M., Avetisov, I. Ch., Azzolini, O., Back, H. O., Balmforth, Z., Barrado-Olmedo, A., Barrillon, P., Basco, A., Batignani, G., Bocci, V., Bonivento, W. M., Bottino, B., Boulay, M. G., Busto, J., Cadeddu, M., Caminata, A., Canci, N., Cappello, G., Capra, A., Caprioli, S., Caravati, M., Cargioli, N., Carlini, M., Castello, P., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Ruiz, J. M. Cela, Chashin, S., Chepurnov, A., Chyhyrynets, E., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Cocco, V., Vilda, E. Conde, Consiglio, L., Copello, S., Covone, G., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Davini, S., de Candia, A., De Cecco, S., De Gruttola, D., De Filippis, G., Dell'Aquila, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Dionisi, C., Di Stefano, P., Dolganov, G., Dordei, F., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Fiorillo, G., Franchini, P., Franco, D., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gendotti, A., Ghiano, C., Giganti, C., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A. L., Hamer, A., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hucker, J., Hugues, T., Ianni, An., Ippolito, V., Jillings, C., Jois, S., Kachru, P., Kemmerich, N., Kemp, A. A., Kendziora, C. L., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Li, X., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Margotti, A., Marik, S. M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Messina, A., Milincic, R., Mitra, A., Moharana, A., Monroe, J., Moretti, E., Morrocchi, M., Mróz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pesudo, V., Piacentini, S., Pino, N., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Ragusa, F., Ramachers, Y., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sabia, M. A., Salomone, P., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sosa, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Tricomi, A., Unzhakov, E. V., John, T. Vallivilayil, Van Uffelen, M., Viant, T., Viel, S., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wingerter-Seez, I., Wojaczynski, R., Wojcik, Ma. M., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors
Abstract: The direct search for dark matter in the form of weakly interacting massive particles (WIMP) is performed by detecting nuclear recoils (NR) produced in a target material from the WIMP elastic scattering. A promising experimental strategy for direct dark matter search employs argon dual-phase time projection chambers (TPC). One of the advantages of the TPC is the capability to detect both the scintillation and charge signals produced by NRs. Furthermore, the existence of a drift electric field in the TPC breaks the rotational symmetry: the angle between the drift field and the momentum of the recoiling nucleus can potentially affect the charge recombination probability in liquid argon and then the relative balance between the two signal channels. This fact could make the detector sensitive to the directionality of the WIMP-induced signal, enabling unmistakable annual and daily modulation signatures for future searches aiming for discovery. The Recoil Directionality (ReD) experiment was designed to probe for such directional sensitivity. The TPC of ReD was irradiated with neutrons at the INFN Laboratori Nazionali del Sud, and data were taken with 72 keV NRs of known recoil directions. The direction-dependent liquid argon charge recombination model by Cataudella et al. was adopted and a likelihood statistical analysis was performed, which gave no indications of significant dependence of the detector response to the recoil direction. The aspect ratio R of the initial ionization cloud is estimated to be 1.037 +/- 0.027 and the upper limit is R < 1.072 with 90% confidence level, Comment: 20 pages, 10 figures, submitted to Eur. Phys. J. C
Published: 2023

5. Sensitivity projections for a dual-phase argon TPC optimized for light dark matter searches through the ionization channel

Author: Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. Ch., Avetisov, R. I., Azzolini, O., Back, H. O., Balmforth, Z., Barbarian, V., Olmedo, A. Barrado, Barrillon, P., Basco, A., Batignani, G., Berzin, E., Bondar, A., Bonivento, W. M., Borisova, E., Bottino, B., Boulay, M. G., Buccino, G., Bussino, S., Busto, J., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castello, P., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Ruiz, J. M. Cela, Chashin, S., Chepurnov, A., Chyhyrynets, E, Cicalò, C., Cifarelli, L., Cintas, D., Cocco, V., Vilda, E. Conde, Consiglio, L., Copello, S., Covone, G., Cross, S., Czudak, P., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Dadoun, O., Daniel, M., Davini, S., De Candia, A., De Cecco, S., De Falco, A., De Filippis, G., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dionisi, C., Dolganov, G., Dordei, F., Doria, L., Erjavec, T., Diaz, M. Fernandez, Fiorillo, G., Franceschi, A., Franchini, P., Franco, D., Frolov, E., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gendotti, A., Ghiano, C., Giampaolo, R. A., Giganti, C., Giorgi, M. A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Gorman, D., Diaz, R. Graciani, Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hall, J. B., Hallin, A. L., Hamer, A., Helton, H., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hugues, T., Hungerford, E. V., Ianni, An., Ippolito, V., Jillings, C., Kachru, P., Kemp, A. A., Kendziora, C. L., Keppel, G., Khomyakov, A. V., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuźniak, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Li, X., Lidey, L., Lipp, J., Lissia, M., Longo, G., Luzzi, L., Macfadyen, O., Machulin, I. N., Manthos, I., Mapelli, L., Margotti, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C. J., Masoni, A., Mavrokoridis, K., Mazzi, A., McDonald, A. B., Messina, A., Milincic, R., Moggi, A., Moharana, A., Monroe, J., Morrocchi, M., Mozhevitina, E. N., Mróz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Napolitano, T., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikulin, I., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pellegrino, C., Perotti, F., Pesudo, V., Piacentini, S., Pietropaolo, F., Pino, N., Pira, C., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Raffaelli, F., Ragusa, F., Ramachers, Y., Ramirez, A., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Resnati, F., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sadashivajois, S., Saffold, T. R., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Scioli, G., Semenov, D. A., Shchagin, A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sokolov, A., Spangenberg, M., Stefanizzi, R., Steri, A., Stracka, S., Strickland, V., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Türkoğ, C., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., John, T. Vallivilayil, Van Uffelen, M., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, Y., Westerdale, S., Wheadon, R. J., Williams, L., Wingerter-Seez, I., Wojaczyński, R., Wojcik, Ma. M., Wojcik, Ma., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: Dark matter lighter than 10 GeV/c$^2$ encompasses a promising range of candidates. A conceptual design for a new detector, DarkSide-LowMass, is presented, based on the DarkSide-50 detector and progress toward DarkSide-20k, optimized for a low-threshold electron-counting measurement. Sensitivity to light dark matter is explored for various potential energy thresholds and background rates. These studies show that DarkSide-LowMass can achieve sensitivity to light dark matter down to the solar neutrino floor for GeV-scale masses and significant sensitivity down to 10 MeV/c$^2$ considering the Migdal effect or interactions with electrons. Requirements for optimizing the detector's sensitivity are explored, as are potential sensitivity gains from modeling and mitigating spurious electron backgrounds that may dominate the signal at the lowest energies.
Published: 2022
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6. Separating $^{39}$Ar from $^{40}$Ar by cryogenic distillation with Aria for dark matter searches

Author: DarkSide Collaboration, Agnes, P., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alici, A., Alton, A. K., Amaudruz, P., Arba, M., Arpaia, P., Arcelli, S., Ave, M., Avetissov, I. Ch., Avetisov, R. I., Azzolini, O., Back, H. O., Balmforth, Z., Barbarian, V., Olmedo, A. Barrado, Barrillon, P., Basco, A., Batignani, G., Bondar, A., Bonivento, W. M., Borisova, E., Bottino, B., Boulay, M. G., Buccino, G., Bussino, S., Busto, J., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canesi, E. V., Canci, N., Cappello, G., Caravati, M., C, M., Cargioli, N., Carlini, M., Carnesecchi, F., Castello, P., Castellani, A., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Ruiz, J. M. Cela, Celano, B., Chashin, S., Chepurnov, A., Cical, C., Cifarelli, L., Cintas, D., Coccetti, F., Cocco, V., Colocci, M., Vilda, E. Conde, Consiglio, L., Copello, S., Corning, J., Covone, G., Czudak, P., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Dadoun, O., Daniel, M., Davini, S., De Candia, A., De Cecco, S., De Falco, A., De Filippis, G., De Gruttola, D., De Guido, G., De Rosa, G., Della Valle, M., Dellacasa, G., De Pasquale, S., Derbin, A. V., Devoto, A., Di Noto, L., Di Eusanio, F., Dionisi, C., Di Stefano, P., Dolganov, G., Dongiovanni, D., Dordei, F., Downing, M., Erjavec, T., Falciano, S., Farenzena, S., Diaz, M. Fernandez, Filip, C., Fiorillo, G., Franceschi, A., Franco, D., Frolov, E., Funicello, N., Gabriele, F., Galbiati, C., Garbini, M., Abia, P. Garcia, Gendotti, A., Ghiano, C., Giampaolo, R. A., Giganti, C., Giorgi, M. A., Giovanetti, G. K., Gligan, M. L., Casanueva, V. Goicoechea, Gola, A., Goretti, A. M., Diaz, R. Graciani, Grigoriev, G. Y., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Guetti, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Haranczyk, M., Hill, S., Horikawa, S., Hubaut, F., Hugues, T., Hungerford, E. V., Ianni, An., Ippolito, V., James, C. C., Jillings, C., Kachru, P., Kemp, A. A., Kendziora, C. L., Keppel, G., Khomyakov, A. V., Kim, S., Kish, A., Kochanek, I., Kondo, K., Korga, G., Kubankin, A., Kugathasan, R., Kuss, M., Kuźniak, M., La Commara, M., La Delfa, L., La Grasta, D., Lai, M., Lami, N., Langrock, S., Leyton, M., Li, X., Lidey, L., Lippi, F., Lissia, M., Longo, G., Maccioni, N., Machulin, I. N., Mapelli, L., Marasciulli, A., Margotti, A., Mari, S. M., Maricic, J., Marinelli, M., Mart, M., Rojas, A. D. Martinez, Martini, A., Martoff, C. J., Mascia, M., Masetto, M., Masoni, A., Mazzi, A., McDonald, A. B., Mclaughlin, J., Messina, A., Meyers, P. D., Miletic, T., Milincic, R., Miola, R., Moggi, A., Moharana, A., Moioli, S., Monroe, J., Morisi, S., Morrocchi, M., Mozhevitina, E. N., Mr, T., Muratova, V. N., Murenu, A., Muscas, C., Musenich, L., Musico, P., Nania, R., Napolitano, T., Agasson, A. Navrer, Nessi, M., Nikulin, I., Nowak, J., Oleinik, A., Oleynikov, V., Pagani, L., Pallavicini, M., Palmas, S., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pellegrini, L. A., Pellegrino, C., Pelczar, K., Perotti, F., Pesudo, V., Picciau, E., Pietropaolo, F., Pinna, T., Pocar, A., Podda, P., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D., Raffaelli, F., Ragusa, F., Ramirez, A., Razeti, M., Razeto, A., Renshaw, A. L., Rescia, S., Rescigno, M., Resnati, F., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Rode, J., Romero, L., Rossi, M., Rubbia, A., Rucaj, M., Sabiu, G. M., Salatino, P., Samoylov, O., S, E., Sandford, E., Sanfilippo, S., Sangiorgio, V. A., Santacroce, V., Santone, D., Santorelli, R., Santucci, A., Savarese, C., Scapparone, E., Schlitzer, B., Scioli, G., Semenov, D. A., Shaw, B., Shchagin, A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smith, B., Sokolov, A., Stefanizzi, R., Steri, A., Stracka, S., Strickland, V., Stringer, M., Sulis, S., Suvorov, Y., Szelc, A. M., Zsücs-Balázs, J. Z., Tartaglia, R., Testera, G., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tosti, S., Tricomi, A., Tuveri, M., Unzhakov, E. V., Usai, G., John, T. Vallivilayil, Vescovi, S., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wheadon, R. J., Williams, L., Wojcik, Ma. M., Wojcik, Ma., Xiao, X., Yang, C., Zani, A., Zenobio, F., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: The Aria project consists of a plant, hosting a 350 m cryogenic isotopic distillation column, the tallest ever built, which is currently in the installation phase in a mine shaft at Carbosulcis S.p.A., Nuraxi-Figus (SU), Italy. Aria is one of the pillars of the argon dark-matter search experimental program, lead by the Global Argon Dark Matter Collaboration. Aria was designed to reduce the isotopic abundance of $^{39}$Ar, a $\beta$-emitter of cosmogenic origin, whose activity poses background and pile-up concerns in the detectors, in the argon used for the dark-matter searches, the so-called Underground Argon (UAr). In this paper, we discuss the requirements, design, construction, tests, and projected performance of the plant for the isotopic cryogenic distillation of argon. We also present the successful results of isotopic cryogenic distillation of nitrogen with a prototype plant, operating the column at total reflux.
Published: 2021
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7. Study of cosmogenic activation above ground for the DarkSide-20k experiment

Author: Elersich, A., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I.F.M., Alexander, T., Alton, A.K., Amaudruz, P., Atzori Corona, M., Ave, M., Avetisov, I.Ch., Azzolini, O., Back, H.O., Balmforth, Z., Barrado-Olmedo, A., Barrillon, P., Basco, A., Batignani, G., Bocci, V., Bonivento, W.M., Bottino, B., Boulay, M.G., Busto, J., Cadeddu, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cargioli, N., Carlini, M., Castello, P., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J.M., Chashin, S., Chepurnov, A., Chyhyrynets, E., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Cocco, V., Colaiuda, D., Conde Vilda, E., Consiglio, L., Copello, S., Covone, G., Czubak, M., D’Aniello, M., D’Auria, S., Da Rocha Rolo, M.D., Davini, S., De Cecco, S., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A.V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dolganov, G., Dordei, F., Ellingwood, E., Erjavec, T., Fernandez Diaz, M., Fiorillo, G., Franchini, P., Franco, D., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giganti, C., Giovanetti, G.K., Goicoechea Casanueva, V., Gola, A., Grauso, G., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B.R., Hallin, A.L., Hamer, A., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hucker, J., Hugues, T., Ianni, An., Ippolito, V., Jillings, C., Jois, S., Kachru, P., Kemp, A.A., Kendziora, C.L., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., La Commara, M., Lai, M., Le Guirriec, E., Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I.N., Manecki, S., Manthos, I., Mapelli, L., Margotti, A., Mari, S.M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C.J., Matteucci, G., Mavrokoridis, K., McDonald, A.B., Messina, A., Milincic, R., Mitra, A., Moharana, A., Monroe, J., Moretti, E., Morrocchi, M., Mróz, T., Muratova, V.N., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., Ortiz de Solórzano, A., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P.A., Pelczar, K., Pellegrino, C., Pesudo, V., Piacentini, S., Pietrofaccia, L., Pino, N., Pocar, A., Poehlmann, D.M., Pordes, S., Pralavorio, P., Price, D., Ragusa, F., Ramachers, Y., Razeti, M., Renshaw, A.L., Rescigno, M., Retiere, F., Rignanese, L.P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sabia, M.A., Salomone, P., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F.G., Scioli, G., Simeone, M., Skensved, P., Skorokhvatov, M.D., Smirnov, O., Smirnova, T., Smith, B., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A.M., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T.N., Tonazzo, A., Tricomi, A., Unzhakov, E.V., Vallivilayil John, T., Van Uffelen, M., Viant, T., Viel, S., Vogelaar, R.B., Vossebeld, J., Wada, M., Walczak, M.B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wingerter-Seez, I., Wojaczynski, R., Wojcik, Ma.M., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M.P.
Published: 2023
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8. Measurement of isotopic separation of argon with the prototype of the cryogenic distillation plant Aria for dark matter searches

Author: Aaron, E., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Atzori Corona, M., Ave, M., Avetisov, I. Ch., Azzolini, O., Back, H. O., Balmforth, Z., Barrado, A., Barrillon, P., Basco, A., Batignani, G., Bocci, V., Bonivento, W. M., Bottino, B., Boulay, M. G., Busto, J., Cadeddu, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cargioli, N., Carlini, M., Castello, P., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J. M., Chashin, S., Chepurnov, A., Chyhyrynets, E., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Cocco, V., Conde Vilda, E., Consiglio, L., Copello, S., Covone, G., Czubak, M., D’Aniello, M., D’Auria, S., Da Rocha Rolo, M. D., Davini, S., De Cecco, S., De Guido, G., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dolganov, G., Dordei, F., Ellingwood, E., Erjavec, T., Farenzena, S., Fernandez Diaz, M., Fiorillo, G., Franchini, P., Franco, D., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giganti, C., Giovanetti, G. K., Goicoechea Casanueva, V., Gola, A., Grauso, G., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A. L., Hamer, A., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hucker, J., Hugues, T., Ianni, An., Ippolito, V., Jillings, C., Jois, S., Kachru, P., Kemp, A. A., Kendziora, C. L., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuźniak, M., La Commara, M., Lai, M., Lami, N., Le Guirriec, E., Leason, E., Leoni, A., Lidey, L., Lippi, F., Lissia, M., Luzzi, L., Lychagina, O., Maccioni, N., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Margotti, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C. J., Mascia, M., Masoni, A., Matteucci, G., Mavrokoridis, K., Maxia, C., McDonald, A. B., Messina, A., Milincic, R., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mróz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Nessi, M., Nikolopoulos, K., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Pellegrino, C., Pesudo, V., Piacentini, S., Pietrofaccia, L., Pino, N., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Ragusa, F., Ramachers, Y., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sabia, M. A., Sabiu, G. M., Salomone, P., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schillaci, G., Schukman, F., Scioli, G., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Tricomi, A., Unzhakov, E. V., Vallivilayil John, T., Van Uffelen, M., Viant, T., Viel, S., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wingerter-Seez, I., Wojaczyński, R., Wojcik, Ma. M., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M. P.
Published: 2023
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9. The European Physical Journal C

Author: Aaron, E., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Atzori Corona, M., Ave, M., Avetisov, I. Ch., Azzolini, O., Back, H. O., Balmforth, Z., Barrado, A., Barrillon, P., Basco, A., Batignani, G., Bocci, V., Bonivento, W. M., Bottino, B., Boulay, M. G., Busto, J., Cadeddu, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cargioli, N., Carlini, M., Castello, P., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J. M., Chashin, S., Chepurnov, A., Chyhyrynets, E., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Cocco, V., Conde Vilda, E., Consiglio, L., Copello, S., Covone, G., Czubak, M., D’Aniello, M., D’Auria, S., Da Rocha Rolo, M. D., Davini, S., De Cecco, S., De Guido, G., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dolganov, G., Dordei, F., Ellingwood, E., Erjavec, T., Farenzena, S., Fernandez Diaz, M., Fiorillo, G., Franchini, P., Franco, D., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giganti, C., Giovanetti, G. K., Goicoechea Casanueva, V., Gola, A., Grauso, G., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A. L., Hamer, A., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hucker, J., Hugues, T., Ianni, An., Ippolito, V., Jillings, C., Jois, S., Kachru, P., Kemp, A. A., Kendziora, C. L., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuźniak, M., La Commara, M., Lai, M., Lami, N., Le Guirriec, E., Leason, E., Leoni, A., Lidey, L., Lippi, F., Lissia, M., Luzzi, L., Lychagina, O., Maccioni, N., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Margotti, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C. J., Mascia, M., Masoni, A., Matteucci, G., Mavrokoridis, K., Maxia, C., Mcdonald, A. B., Messina, A., Milincic, R., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mróz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Nessi, M., Nikolopoulos, K., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., Ortiz de Solórzano, A., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Pellegrino, C., Pesudo, V., Piacentini, S., Pietrofaccia, L., Pino, N., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Ragusa, F., Ramachers, Y., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sabia, M. A., Sabiu, G. M., Salomone, P., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schillaci, G., Schukman, F., Scioli, G., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Tricomi, A., Unzhakov, E. V., Vallivilayil John, T., Van Uffelen, M., Viant, T., Viel, S., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wingerter-Seez, I., Wojaczyński, R., Wojcik, Ma. M., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., Zykova &amp, M. P., DarkSide-20k, Collaboration, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), DarkSide-20k, Aaron, E., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Atzori Corona, M., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Barrado, A., Barrillon, P., Basco, A., Batignani, G., Bocci, V., Bonivento, W. M., Bottino, B., Boulay, M. G., Busto, J., Cadeddu, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cargioli, N., Carlini, M., Castello, P., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J. M., Chashin, S., Chepurnov, A., Chyhyrynets, E., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Cocco, V., Conde Vilda, E., Consiglio, L., Copello, S., Covone, G., Czubak, M., D'Aniello, M., D'Auria, S., Da Rocha Rolo, M. D., Davini, S., De Cecco, S., De Guido, G., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dolganov, G., Dordei, F., Ellingwood, E., Erjavec, T., Farenzena, S., Fernandez Diaz, M., Fiorillo, G., Franchini, P., Franco, D., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giganti, C., Giovanetti, G. K., Goicoechea Casanueva, V., Gola, A., Grauso, G., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A. L., Hamer, A., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hucker, J., Hugues, T., Ianni, A., Ippolito, V., Jillings, C., Jois, S., Kachru, P., Kemp, A. A., Kendziora, C. L., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., La Commara, M., Lai, M., Lami, N., Le Guirriec, E., Leason, E., Leoni, A., Lidey, L., Lippi, F., Lissia, M., Luzzi, L., Lychagina, O., Maccioni, N., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Margotti, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martinez, M., Martoff, C. J., Mascia, M., Masoni, A., Matteucci, G., Mavrokoridis, K., Maxia, C., Mcdonald, A. B., Messina, A., Milincic, R., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Nessi, M., Nikolopoulos, K., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solorzano, A. O., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Pellegrino, C., Pesudo, V., Piacentini, S., Pietrofaccia, L., Pino, N., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Ragusa, F., Ramachers, Y., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sabia, M. A., Sabiu, G. M., Salomone, P., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schillaci, G., Schukman, F., Scioli, G., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Tricomi, A., Unzhakov, E. V., Vallivilayil John, T., Van Uffelen, M., Viant, T., Viel, S., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wingerter-Seez, I., Wojaczynski, R., Wojcik, M. M., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, WIMP, dark matter, DarkSide-20k, stability, buildings, programming, nitrogen, cryogenic distillation, Gran Sasso, astro-ph.IM, cryogenics, quality, Dark Matter, Argon, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Astrophysics - Instrumentation and Methods for Astrophysics, experimental results
Abstract: The Aria cryogenic distillation plant, located in Sardinia, Italy, is a key component of the DarkSide-20k experimental program for WIMP dark matter searches at the INFN Laboratori Nazionali del Gran Sasso, Italy. Aria is designed to purify the argon, extracted from underground wells in Colorado, USA, and used as the DarkSide-20k target material, to detector-grade quality. In this paper, we report the first measurement of argon isotopic separation by distillation with the 26 m tall Aria prototype. We discuss the measurement of the operating parameters of the column and the observation of the simultaneous separation of the three stable argon isotopes: $${}^{36}\hbox {Ar}$$ 36 Ar , $${}^{38}\textrm{Ar}$$ 38 Ar , and $${}^{40}\textrm{Ar}$$ 40 Ar . We also provide a detailed comparison of the experimental results with commercial process simulation software. This measurement of isotopic separation of argon is a significant achievement for the project, building on the success of the initial demonstration of isotopic separation of nitrogen using the same equipment in 2019.
Published: 2023

10. Separating $^{39}$Ar from $^{40}$Ar by cryogenic distillation with Aria for dark matter searches

Author: Agnes, P., Albergo, S., Albuquerque, I.F.M., Alexander, T., Alici, A., Alton, A.K., Amaudruz, P., Arba, M., Arpaia, P., Arcelli, S., Ave, M., Avetissov, I.Ch., Avetisov, R.I., Azzolini, O., Back, H.O., Balmforth, Z., Barbarian, V., Olmedo, A. Barrado, Barrillon, P., Basco, A., Batignani, G., Bondar, A., Bonivento, W.M., Borisova, E., Bottino, B., Boulay, M.G., Buccino, G., Bussino, S., Busto, J., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canesi, E.V., Canci, N., Cappello, G., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Carnesecchi, F., Castello, P., Castellani, A., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J.M., Celano, B., Chashin, S., Chepurnov, A., Cicalò, C., Cifarelli, L., Cintas, D., Coccetti, F., Cocco, V., Colocci, M., Vilda, E. Conde, Consiglio, L., Copello, S., Corning, J., Covone, G., Czudak, P., d'Aniello, M., d'Auria, S., da Rocha Rolo, M., Dadoun, O., Daniel, M., Davini, S., de Candia, A., De Cecco, S., De Falco, A., de Filippis, G., De Gruttola, D., De Guido, G., De Rosa, G., Della Valle, M., Dellacasa, G., De Pasquale, S., Derbin, A.V., Devoto, A., Di Noto, L., Di Eusanio, F., Dionisi, C., Di Stefano, P., Dolganov, G., Dongiovanni, D., Dordei, F., Downing, M., Erjavec, T., Falciano, S., Farenzena, S., Diaz, M. Fernandez, Filip, C., Fiorillo, G., Franceschi, A., Franco, D., Frolov, E., Funicello, N., Gabriele, F., Galbiati, C., Garbini, M., Abia, P. Garcia, Gendotti, A., Ghiano, C., Giampaolo, R.A., Giganti, C., Giorgi, M.A., Giovanetti, G.K., Gligan, M.L., Casanueva, V. Goicoechea, Gola, A., Goretti, A.M., Graciani Diaz, R., Grigoriev, G.Y., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Guetti, M., Gulino, M., Guo, C., Hackett, B.R., Hallin, A., Haranczyk, M., Hill, S., Horikawa, S., Hubaut, F., Hugues, T., Hungerford, E.V., Ianni, An., Ippolito, V., James, C.C., Jillings, C., Kachru, P., Kemp, A.A., Kendziora, C.L., Keppel, G., Khomyakov, A.V., Kim, S., Kish, A., Kochanek, I., Kondo, K., Korga, G., Kubankin, A., Kugathasan, R., Kuss, M., Kuźniak, M., La Commara, M., La Delfa, L., La Grasta, D., Lai, M., Lami, N., Langrock, S., Leyton, M., Li, X., Lidey, L., Lippi, F., Lissia, M., Longo, G., Maccioni, N., Machulin, I.N., Mapelli, L., Marasciulli, A., Margotti, A., Mari, S.M., Maricic, J., Marinelli, M., Martínez, M., Rojas, A.D. Martinez, Martini, A., Martoff, C.J., Mascia, M., Masetto, M., Masoni, A., Mazzi, A., Mcdonald, A.B., Mclaughlin, J., Messina, A., Meyers, P.D., Miletic, T., Milincic, R., Miola, R., Moggi, A., Moharana, A., Moioli, S., Monroe, J., Morisi, S., Morrocchi, M., Mozhevitina, E.N., Mr, T., Mróz, T., Muratova, V.N., Murenu, A., Muscas, C., Musenich, L., Musico, P., Nania, R., Napolitano, T., Navrer Agasson, A., Nessi, M., Nikulin, I., Nowak, J., Oleinik, A., Oleynikov, V., Pagani, L., Pallavicini, M., Palmas, S., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P.A., Pellegrini, L.A., Pellegrino, C., Pelczar, K., Perotti, F., Pesudo, V., Picciau, E., Pietropaolo, F., Pinna, T., Pocar, A., Podda, P., Poehlmann, D.M., Pordes, S., Poudel, S.S., Pralavorio, P., Price, D., Raffaelli, F., Ragusa, F., Ramirez, A., Razeti, M., Razeto, A., Renshaw, A.L., Rescia, S., Rescigno, M., Resnati, F., Retiere, F., Rignanese, L.P., Ripoli, C., Rivetti, A., Rode, J., Romero, L., Rossi, M., Rubbia, A., Rucaj, M., Sabiu, G.M., Salatino, P., Samoylov, O., Sánchez García, E., Sandford, E., Sanfilippo, S., Sangiorgio, V.A., Santacroce, V., Santone, D., Santorelli, R., Santucci, A., Savarese, C., Scapparone, E., Schlitzer, B., Scioli, G., Semenov, D.A., Shaw, B., Shchagin, A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M.D., Smirnov, O., Smith, B., Sokolov, A., Stefanizzi, R., Steri, A., Stracka, S., Strickland, V., Stringer, M., Sulis, S., Suvorov, Y., Szelc, A.M., Zsücs-Balázs, J.Z., Tartaglia, R., Testera, G., Thorpe, T.N., Tonazzo, A., Torres-Lara, S., Tosti, S., Tricomi, A., Tuveri, M., Unzhakov, E.V., Usai, G., John, T. Vallivilayil, Vescovi, S., Viant, T., Viel, S., Vishneva, A., Vogelaar, R.B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wheadon, R.J., Williams, L., Wojcik, Ma.M., Wojcik, Ma., Xiao, X., Yang, C., Zani, A., Zenobio, F., Zichichi, A., Zuzel, G., Zykova, M.P., Agnes P., Albergo S., Albuquerque I.F.M., Alexander T., Alici A., Alton A.K., Amaudruz P., Arba M., Arpaia P., Arcelli S., Ave M., Avetissov I.C., Avetisov R.I., Azzolini O., Back H.O., Balmforth Z., Barbarian V., Barrado Olmedo A., Barrillon P., Basco A., Batignani G., Bondar A., Bonivento W.M., Borisova E., Bottino B., Boulay M.G., Buccino G., Bussino S., Busto J., Buzulutskov A., Cadeddu M., Cadoni M., Caminata A., Canesi E.V., Canci N., Cappello G., Caravati M., Cardenas-Montes M., Cargioli N., Carlini M., Carnesecchi F., Castello P., Castellani A., Catalanotti S., Cataudella V., Cavalcante P., Cavuoti S., Cebrian S., Cela Ruiz J.M., Celano B., Chashin S., Chepurnov A., Cicalo C., Cifarelli L., Cintas D., Coccetti F., Cocco V., Colocci M., Conde Vilda E., Consiglio L., Copello S., Corning J., Covone G., Czudak P., D'Aniello M., D'Auria S., Da Rocha Rolo M.D., Dadoun O., Daniel M., Davini S., De Candia A., De Cecco S., De Falco A., De Filippis G., De Gruttola D., De Guido G., De Rosa G., Della Valle M., Dellacasa G., De Pasquale S., Derbin A.V., Devoto A., Di Noto L., Di Eusanio F., Dionisi C., Di Stefano P., Dolganov G., Dongiovanni D., Dordei F., Downing M., Erjavec T., Falciano S., Farenzena S., Fernandez Diaz M., Filip C., Fiorillo G., Franceschi A., Franco D., Frolov E., Funicello N., Gabriele F., Galbiati C., Garbini M., Garcia Abia P., Gendotti A., Ghiano C., Giampaolo R.A., Giganti C., Giorgi M.A., Giovanetti G.K., Gligan M.L., Goicoechea Casanueva V., Gola A., Goretti A.M., Graciani Diaz R., Grigoriev G.Y., Grobov A., Gromov M., Guan M., Guerzoni M., Guetti M., Gulino M., Guo C., Hackett B.R., Hallin A., Haranczyk M., Hill S., Horikawa S., Hubaut F., Hugues T., Hungerford E.V., Ianni A., Ippolito V., James C.C., Jillings C., Kachru P., Kemp A.A., Kendziora C.L., Keppel G., Khomyakov A.V., Kish A., Kochanek I., Kondo K., Korga G., Kubankin A., Kugathasan R., Kuss M., Kuzniak M., La Commara M., La Delfa L., La Grasta D., Lai M., Lami N., Langrock S., Leyton M., Li X., Lidey L., Lippi F., Lissia M., Longo G., Maccioni N., Machulin I.N., Mapelli L., Marasciulli A., Margotti A., Mari S.M., Maricic J., Marinelli M., Martinez M., Martinez Rojas A.D., Martini A., Mascia M., Masetto M., Masoni A., Mazzi A., McDonald A.B., Mclaughlin J., Messina A., Meyers P.D., Miletic T., Milincic R., Miola R., Moggi A., Moharana A., Moioli S., Monroe J., Morisi S., Morrocchi M., Mozhevitina E.N., Mroz T., Muratova V.N., Murenu A., Muscas C., Musenich L., Musico P., Nania R., Napolitano T., Navrer Agasson A., Nessi M., Nikulin I., Nowak J., Oleinik A., Oleynikov V., Pagani L., Pallavicini M., Palmas S., Pandola L., Pantic E., Paoloni E., Paternoster G., Pegoraro P.A., Pellegrini L.A., Pellegrino C., Pelczar K., Perotti F., Pesudo V., Picciau E., Pietropaolo F., Pinna T., Pocar A., Podda P., Poehlmann D.M., Pordes S., Poudel S.S., Pralavorio P., Price D., Raffaelli F., Ragusa F., Ramirez A., Razeti M., Razeto A., Renshaw A.L., Rescia S., Rescigno M., Resnati F., Retiere F., Rignanese L.P., Ripoli C., Rivetti A., Rode J., Romero L., Rossi M., Rubbia A., Rucaj M., Sabiu G.M., Salatino P., Samoylov O., Sanchez Garcia E., Sandford E., Sanfilippo S., Sangiorgio V.A., Santacroce V., Santone D., Santorelli R., Santucci A., Savarese C., Scapparone E., Schlitzer B., Scioli G., Semenov D.A., Shaw B., Shchagin A., Sheshukov A., Simeone M., Skensved P., Skorokhvatov M.D., Smirnov O., Smith B., Sokolov A., Stefanizzi R., Steri A., Stracka S., Strickland V., Stringer M., Sulis S., Suvorov Y., Szelc A.M., Szucs-Balazs J.Z., Tartaglia R., Testera G., Thorpe T.N., Tonazzo A., Torres-Lara S., Tosti S., Tricomi A., Tuveri M., Unzhakov E.V., Usai G., Vallivilayil John T., Vescovi S., Viant T., Viel S., Vishneva A., Vogelaar R.B., Wada M., Wang H., Wang Y., Westerdale S., Wheadon R.J., Williams L., M.Wojcik M., Wojcik M., Xiao X., Yang C., Zani A., Zenobio F., Zichichi A., Zuzel G., Zykova M.P., Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), DarkSide-20k, Agnes, P., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alici, A., Alton, A. K., Amaudruz, P., Arba, M., Arpaia, P., Arcelli, S., Ave, M., Avetissov, I. C., Avetisov, R. I., Azzolini, O., Back, H. O., Balmforth, Z., Barbarian, V., Barrado Olmedo, A., Barrillon, P., Basco, A., Batignani, G., Bondar, A., Bonivento, W. M., Borisova, E., Bottino, B., Boulay, M. G., Buccino, G., Bussino, S., Busto, J., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canesi, E. V., Canci, N., Cappello, G., Caravati, M., Cardenas-Montes, M., Cargioli, N., Carlini, M., Carnesecchi, F., Castello, P., Castellani, A., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J. M., Celano, B., Chashin, S., Chepurnov, A., Cicalo, C., Cifarelli, L., Cintas, D., Coccetti, F., Cocco, V., Colocci, M., Conde Vilda, E., Consiglio, L., Copello, S., Corning, J., Covone, G., Czudak, P., D'Aniello, M., D'Auria, S., Da Rocha Rolo, M. D., Dadoun, O., Daniel, M., Davini, S., De Candia, A., De Cecco, S., De Falco, A., De Filippis, G., De Gruttola, D., De Guido, G., De Rosa, G., Della Valle, M., Dellacasa, G., De Pasquale, S., Derbin, A. V., Devoto, A., Di Noto, L., Di Eusanio, F., Dionisi, C., Di Stefano, P., Dolganov, G., Dongiovanni, D., Dordei, F., Downing, M., Erjavec, T., Falciano, S., Farenzena, S., Fernandez Diaz, M., Filip, C., Fiorillo, G., Franceschi, A., Franco, D., Frolov, E., Funicello, N., Gabriele, F., Galbiati, C., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giampaolo, R. A., Giganti, C., Giorgi, M. A., Giovanetti, G. K., Gligan, M. L., Goicoechea Casanueva, V., Gola, A., Goretti, A. M., Graciani Diaz, R., Grigoriev, G. Y., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Guetti, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Haranczyk, M., Hill, S., Horikawa, S., Hubaut, F., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., James, C. C., Jillings, C., Kachru, P., Kemp, A. A., Kendziora, C. L., Keppel, G., Khomyakov, A. V., Kish, A., Kochanek, I., Kondo, K., Korga, G., Kubankin, A., Kugathasan, R., Kuss, M., Kuzniak, M., La Commara, M., La Delfa, L., La Grasta, D., Lai, M., Lami, N., Langrock, S., Leyton, M., Li, X., Lidey, L., Lippi, F., Lissia, M., Longo, G., Maccioni, N., Machulin, I. N., Mapelli, L., Marasciulli, A., Margotti, A., Mari, S. M., Maricic, J., Marinelli, M., Martinez, M., Martinez Rojas, A. D., Martini, A., Mascia, M., Masetto, M., Masoni, A., Mazzi, A., Mcdonald, A. B., Mclaughlin, J., Messina, A., Meyers, P. D., Miletic, T., Milincic, R., Miola, R., Moggi, A., Moharana, A., Moioli, S., Monroe, J., Morisi, S., Morrocchi, M., Mozhevitina, E. N., Mroz, T., Muratova, V. N., Murenu, A., Muscas, C., Musenich, L., Musico, P., Nania, R., Napolitano, T., Navrer Agasson, A., Nessi, M., Nikulin, I., Nowak, J., Oleinik, A., Oleynikov, V., Pagani, L., Pallavicini, M., Palmas, S., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pellegrini, L. A., Pellegrino, C., Pelczar, K., Perotti, F., Pesudo, V., Picciau, E., Pietropaolo, F., Pinna, T., Pocar, A., Podda, P., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D., Raffaelli, F., Ragusa, F., Ramirez, A., Razeti, M., Razeto, A., Renshaw, A. L., Rescia, S., Rescigno, M., Resnati, F., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Rode, J., Romero, L., Rossi, M., Rubbia, A., Rucaj, M., Sabiu, G. M., Salatino, P., Samoylov, O., Sanchez Garcia, E., Sandford, E., Sanfilippo, S., Sangiorgio, V. A., Santacroce, V., Santone, D., Santorelli, R., Santucci, A., Savarese, C., Scapparone, E., Schlitzer, B., Scioli, G., Semenov, D. A., Shaw, B., Shchagin, A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smith, B., Sokolov, A., Stefanizzi, R., Steri, A., Stracka, S., Strickland, V., Stringer, M., Sulis, S., Suvorov, Y., Szelc, A. M., Szucs-Balazs, J. Z., Tartaglia, R., Testera, G., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tosti, S., Tricomi, A., Tuveri, M., Unzhakov, E. V., Usai, G., Vallivilayil John, T., Vescovi, S., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wheadon, R. J., Williams, L., M. Wojcik, M., Wojcik, M., Xiao, X., Yang, C., Zani, A., Zenobio, F., Zichichi, A., Zuzel, G., Zykova, M. P., Avetissov, I. Ch., Cárdenas-Montes, M., Cicalò, C., D’Aniello, M., D’Auria, S., Ianni, An., Kuźniak, M., Martínez, M., Mróz, T., Sánchez García, E., Wojcik, Ma. M., Wojcik, Ma., Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), and ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018)
Subjects: Astrophysics and Astronomy, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, FOS: Physical sciences, isotopic distillation argon cryogenic, Instrumentation and Detectors (physics.ins-det), dark matter: detector, fabrication, argon: nuclide, astro-ph.IM, dark-matter, DarkSide-20k, Argon, cryogenics, pile-up, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Detectors and Experimental Techniques, Astrophysics - Instrumentation and Methods for Astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM), physics.ins-det, performance
Abstract: Aria is a plant hosting a ${350}\,\hbox {m}$ cryogenic isotopic distillation column, the tallest ever built, which is being installed in a mine shaft at Carbosulcis S.p.A., Nuraxi-Figus (SU), Italy. Aria is one of the pillars of the argon dark-matter search experimental program, lead by the Global Argon Dark Matter Collaboration. It was designed to reduce the isotopic abundance of ${^{39}\hbox {Ar}}$ in argon extracted from underground sources, called Underground Argon (UAr), which is used for dark-matter searches. Indeed, ${^{39}\hbox {Ar}}$ is a $\beta $-emitter of cosmogenic origin, whose activity poses background and pile-up concerns in the detectors. In this paper, we discuss the requirements, design, construction, tests, and projected performance of the plant for the isotopic cryogenic distillation of argon. We also present the successful results of the isotopic cryogenic distillation of nitrogen with a prototype plant. The Aria project consists of a plant, hosting a 350 m cryogenic isotopic distillation column, the tallest ever built, which is currently in the installation phase in a mine shaft at Carbosulcis S.p.A., Nuraxi-Figus (SU), Italy. Aria is one of the pillars of the argon dark-matter search experimental program, lead by the Global Argon Dark Matter Collaboration. Aria was designed to reduce the isotopic abundance of $^{39}$Ar, a $\beta$-emitter of cosmogenic origin, whose activity poses background and pile-up concerns in the detectors, in the argon used for the dark-matter searches, the so-called Underground Argon (UAr). In this paper, we discuss the requirements, design, construction, tests, and projected performance of the plant for the isotopic cryogenic distillation of argon. We also present the successful results of isotopic cryogenic distillation of nitrogen with a prototype plant, operating the column at total reflux.
Published: 2021

11. Separating $${^{39}\hbox {Ar}}$$ <math> <mrow> <msup> <mrow></mrow> <mn>39</mn> </msup> <mtext>Ar</mtext> </mrow> </math> from $${^{40}\hbox {Ar}}$$ <math> <mrow> <msup> <mrow></mrow> <mn>40</mn> </msup> <mtext>Ar</mtext> </mrow> </math> by cryogenic distillation with Aria for dark-matter searches

Author: Agnes, P., Albergo, S., Albuquerque, I., Alexander, T., Alici, A., Alton, A., Amaudruz, P., Arba, M., Arpaia, P., Arcelli, S., Ave, M., Avetissov, I., Avetisov, R., Azzolini, O., Back, H., Balmforth, Z., Barbarian , V., Barrado Olmedo, A., Barrillon, P., Basco, A., Batignani, G., Bondar, A., Bonivento, W., Borisova, E., Bottino, B., Boulay, M., Buccino, G., Bussino, S., Busto, J., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canesi, E., Canci, N., Cappello, G., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini , M., Carnesecchi, F., Castello, P., Castellani, A., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J., Celano, B., Chashin, S., Chepurnov, A., Cicalò, C., Cifarelli, L., Cintas, D., Coccetti, F., Cocco, V., Colocci, M., Conde Vilda, E., Consiglio, L., Copello, S., Corning, J., Covone, G., Czudak, P., D’Aniello, M., D’Auria, S., Da Rocha Rolo, M., Dadoun, O., Daniel, M., Davini, S., De Candia , A., De Cecco, S., De Falco, A., De Filippis, G., De Gruttola, D., De Guido, G., De Rosa, G., Della Valle, M., Dellacasa, G., De Pasquale, S., Derbin, A., Devoto, A., Di Noto, L., Di Eusanio, F., Dionisi, C., Di Stefano, P., Dolganov, G., Dongiovanni, D., Dordei, F., Downing, M., Erjavec, T., Falciano, S., Farenzena, S., Fernandez Diaz, M., Filip, C., Fiorillo, G., Franceschi, A., Franco, D., Frolov, E., Funicello, N., Gabriele, F., Galbiati, C., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giampaolo, R., Giganti, C., Giorgi, M., Giovanetti, G., Gligan, M., Goicoechea Casanueva, V., Gola, A., Goretti, A., Graciani Diaz, R., Grigoriev, G., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Guetti, M., Gulino, M., Guo, C., Hackett, B., Hallin, A., Haranczyk, M., Hill, S., Horikawa, S., Hubaut, F., Hugues, T., Hungerford, E., Ianni, An., Ippolito, V., James, C., Jillings, C., Kachru, P., Kemp, A., Kendziora, C., Keppel, G., Khomyakov, A., Kish, A., Kochanek, I., Kondo, K., Korga, G., Kubankin, A., Kugathasan, R., Kuss, M., Kuźniak, M., La Commara, M., La Delfa, L., La Grasta, D., Lai, M., Lami, N., Langrock, S., Leyton, M., Li, X., Lidey, L., Lippi, F., Lissia, M., Longo, G., Maccioni, N., Machulin, I., Mapelli, L., Marasciulli, A., Margotti, A., Mari, S., Maricic, J., Marinelli, M., Martínez, M., Martinez Rojas, A., Martini, A., Mascia, M., Masetto, M., Masoni, A., Mazzi, A., McDonald, A., Mclaughlin, J., Messina, A., Meyers, P., Miletic, T., Milincic, R., Miola, R., Moggi, A., Moharana, A., Moioli, S., Monroe, J., Morisi, S., Morrocchi, M., Mozhevitina, E., Mróz, T., Muratova, V., Murenu, A., Muscas, C., Musenich, L., Musico, P., Nania, R., Napolitano, T., Navrer Agasson, A., Nessi, M., Nikulin, I., Nowak, J., Oleinik, A., Oleynikov, V., Pagani, L., Pallavicini, M., Palmas, S., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P., Pellegrini, L., Pellegrino, C., Pelczar, K., Perotti, F., Pesudo, V., Picciau, E., Pietropaolo, F., Pinna, T., Pocar, A., Podda, P., Poehlmann, D., Pordes, S., Poudel, S., Pralavorio, P., Price, D., Raffaelli, F., Ragusa, F., Ramirez, A., Razeti, M., Razeto, A., Renshaw, A., Rescia, S., Rescigno, M., Resnati, F., Retiere, F., Rignanese , L., Ripoli, C., Rivetti, A., Rode, J., Romero, L., Rossi, M., Rubbia, A., Rucaj, M., Sabiu, G., Salatino, P., Samoylov, O., Sánchez García, E., Sandford, E., Sanfilippo, S., Sangiorgio, V., Santacroce, V., Santone, D., Santorelli, R., Santucci, A., Savarese, C., Scapparone, E., Schlitzer, B., Scioli, G., Semenov, D., Shaw, B., Shchagin, A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M., Smirnov, O., Smith, B., Sokolov, A., Stefanizzi, R., Steri, A., Stracka, S., Strickland , V., Stringer, M., Sulis, S., Suvorov, Y., Szelc, A., Szucs-Balazs, J., Tartaglia, R., Testera, G., Thorpe, T., Tonazzo, A., Torres-Lara, S., Tosti, S., Tricomi, A., Tuveri, M., Unzhakov, E., Usai, G., Vallivilayil John, T., Vescovi, S., Viant, T., Viel, S., Vishneva , A., Vogelaar, R., Wada, M., Wang, H., Wang, Y., Westerdale , S., Wheadon, R., Williams, L., M.Wojcik, Ma., Wojcik, Ma., Xiao, X., Yang, C., Zani, A., Zenobio, F., Zichichi, A., Zuzel, G., and Zykova, M.
Abstract: Aria is a plant hosting a $${350}\,\hbox {m}$$ 350 m cryogenic isotopic distillation column, the tallest ever built, which is being installed in a mine shaft at Carbosulcis S.p.A., Nuraxi-Figus (SU), Italy. Aria is one of the pillars of the argon dark-matter search experimental program, lead by the Global Argon Dark Matter Collaboration. It was designed to reduce the isotopic abundance of $${^{39}\hbox {Ar}}$$ 39 Ar in argon extracted from underground sources, called Underground Argon (UAr), which is used for dark-matter searches. Indeed, $${^{39}\hbox {Ar}}$$ 39 Ar is a $$\beta $$ β -emitter of cosmogenic origin, whose activity poses background and pile-up concerns in the detectors. In this paper, we discuss the requirements, design, construction, tests, and projected performance of the plant for the isotopic cryogenic distillation of argon. We also present the successful results of the isotopic cryogenic distillation of nitrogen with a prototype plant.
Published: 2021

12. P011 Just a spoonful of sugar helps the medicine go down: L-arginine pill related esophageal ulcer, the first pediatric case report

Author: Gaio, P., primary, Bosa, L., additional, Rossin, S., additional, Buccella, V., additional, Nai Fovino, L., additional, Stefanizzi, R., additional, Mescoli, C., additional, Perilongo, G., additional, and Cananzi, M., additional
Published: 2018
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13. [Quality of life, depression and cognitive functions 1. Operational protocol and its implementation]

Author: Rete Infermieri GISSI HF, Di Giulio P, Pera C, Scarano M, Ferri B, Lepore V, Miani D, Tognoni G, Rosson V, Serafini C, Zumino T, Partemi L, Falleroni ML, Moretti L, Porta L, Santorsola A, Tenerelli T, Bertoncelli B, Mengoli G, Stagnitto M, Puddu GM, Masini E, Pasini A, Boni S, Valsesia E, Cornacini G, Melis D, Mulina A, Giurlanda A, Fava M, Bellini P, Vallucci S, Cuomo A, Campanale S, Monatti G, Bianco T, Milli V, Antonelli L, Fanin L, Faiola L, Stefanizzi R, Mariani M, Rossi A, Regnani T, Loreni F, Cianfrocca R, Pisani A, Faraolfi V, Ponzalli P, Savli T, Cresci M, Guardalben S, Belluzzo B, Ruberti R, Zizzi M, Tonda C, Cadrobbi MG, Gilardi R, Mondì A, Costa A, Milan S, Zottarelli A, Parodi B, Sartorio N, Rossin B, Santi A, Cagnan P, Maradei E, Cauteruccio A, Carpino C, Addeo R, Izzo A, Amendola G, Prizzitano AM, Piluso GM, Iadevaio AL, Cinà MT, Cirrincione V, Gumina S, Codato G, Raimondo F, Capiello MG, Creta F, Barbieri M, Chiarella L, Abbondio L, Piccin M, Spillone V, Cutrupi G, Ruggeri A, Sicilia G, Provengano A, Marcari P, Ricci S, Pazzagli E, La Grotteria M, Orsini R, Leandri L, Vetere NA, Braggion E, Giordanino S, Armando S, Zampieri E, Danese MC, Valentini A, Ferrante MG, Santacroce C, Crocetti I, Macchi F, Bernacchi M, Pini D, Varì M, Lucente M, Scaramastra F, Reichardt S, Gabasio S, Zocchi C, Studhika M, Budzowska E, Cescon M, Lazzari D, Prizzon A, Di Biaggio P, Buda C, Mastrangelo V, Avigliano M, Dell'Aquila L, Bonanomi E, Mezzani A, Porcini F, Girardi G., PERRONE FILARDI, PASQUALE, Rete Infermieri GISSI, Hf, Di Giulio, P, Pera, C, Scarano, M, Ferri, B, Lepore, V, Miani, D, Tognoni, G, Rosson, V, Serafini, C, Zumino, T, Partemi, L, Falleroni, Ml, Moretti, L, Porta, L, Santorsola, A, Tenerelli, T, Bertoncelli, B, Mengoli, G, Stagnitto, M, Puddu, Gm, Masini, E, Pasini, A, Boni, S, Valsesia, E, Cornacini, G, Melis, D, Mulina, A, Giurlanda, A, Fava, M, Bellini, P, Vallucci, S, Cuomo, A, Campanale, S, Monatti, G, Bianco, T, Milli, V, Antonelli, L, Fanin, L, Faiola, L, Stefanizzi, R, Mariani, M, Rossi, A, Regnani, T, Loreni, F, Cianfrocca, R, Pisani, A, Faraolfi, V, Ponzalli, P, Savli, T, Cresci, M, Guardalben, S, Belluzzo, B, Ruberti, R, Zizzi, M, Tonda, C, Cadrobbi, Mg, Gilardi, R, Mondì, A, Costa, A, Milan, S, Zottarelli, A, Parodi, B, Sartorio, N, Rossin, B, Santi, A, Cagnan, P, Maradei, E, Cauteruccio, A, Carpino, C, Addeo, R, Izzo, A, Amendola, G, PERRONE FILARDI, Pasquale, Prizzitano, Am, Piluso, Gm, Iadevaio, Al, Cinà, Mt, Cirrincione, V, Gumina, S, Codato, G, Raimondo, F, Capiello, Mg, Creta, F, Barbieri, M, Chiarella, L, Abbondio, L, Piccin, M, Spillone, V, Cutrupi, G, Ruggeri, A, Sicilia, G, Provengano, A, Marcari, P, Ricci, S, Pazzagli, E, La Grotteria, M, Orsini, R, Leandri, L, Vetere, Na, Braggion, E, Giordanino, S, Armando, S, Zampieri, E, Danese, Mc, Valentini, A, Ferrante, Mg, Santacroce, C, Crocetti, I, Macchi, F, Bernacchi, M, Pini, D, Varì, M, Lucente, M, Scaramastra, F, Reichardt, S, Gabasio, S, Zocchi, C, Studhika, M, Budzowska, E, Cescon, M, Lazzari, D, Prizzon, A, Di Biaggio, P, Buda, C, Mastrangelo, V, Avigliano, M, Dell'Aquila, L, Bonanomi, E, Mezzani, A, Porcini, F, and Girardi, G.
Subjects: Time Factors, Depression, Cardiology, Prognosis, Nursing Research, Cognition, Clinical Protocols, Italy, Data Interpretation, Statistical, Surveys and Questionnaires, Quality of Life, Humans, Cardiomyopathies, Geriatric Assessment, Aged, Randomized Controlled Trials as Topic
Abstract: The QDF (Quality of life, Depression and cognitive Function) is a project elaborated and implemented by a Research Network of the nursing personnel of the cardiological services which promoted and run the GISSI-HF trial. It is a "companion study" which included up to 1/3 of all the GISSI-HF centres.To describe the distribution and evaluation of QDF variables measured with standardised instruments (Kansas City Cardiomiopathy Quality of Life questionnaire, KCCQ; Geriaric Depression scale GDS, Mini Mental State Examination MMSE), to verify whether and how far their knowledge could influence clinical decisions; to assess the prognostic impact of QDF values measured at entrance on mortality and morbidity. The study protocol included also a comprehensive evaluation of QDF variables independent from the questionnaires, by the nurses in charge of the study patients (the results of this part of the protocol are not included in this report).The QDF data were collected at baseline, 6 months, 1, 2 and 3 years through two self administered questionnaires (KCCQ, GDS), while the MMSE only for patients70 years. The questionnaires were administered to the patients who accepted to participate. A specific goal of the project focuses on the degree of independence between the results of the questionnaires and the judgement of the nurses. This contribution presents the operational implementation of the study protocol and general framework.
Published: 2009

14. [Quality of life, depression and cognitive functions 2. Methodological aspects and data quality]

Author: Rete Infermieri GISSI HF, Di Giulio P, Pera C, Scarano M, Ferri B, Lepore V, Miani D, Tognoni G, Rosson V, Serafini C, Zumino MT, Partemi L, Falleroni ML, Moretti L, Porta L, Santorsola A, Tenerelli T, Bertoncelli B, Mengoli G, Stagnitto M, Puddu GM, Masini E, Pasini A, Boni S, Valsesia E, Cornacini G, Melis D, Mulina A, Giurlanda A, Fava M, Bellini P, Vallucci S, Cuomo A, Campanale S, Monatti G, Bianco T, Milli V, Antonelli L, Fanin L, Faiola L, Stefanizzi R, Mariani M, Rossi A, Regnani ST, Loreni F, Cianfrocca R, Pisani A, Faraolfi V, Ponzalli P, Savli T, Cresci M, Guardalben S, Belluzzo B, Ruberti R, Zizzi M, Tonda C, Cadrobbi MG, Gilardi R, Mondì A, Costa A, Milan S, Zottarelli A, Parodi B, Sartorio N, Rossin B, Santi A, Cagnan P, Maradei E, Cauteruccio A, Carpino C, Addeo R, Izzo A, Amendola G, Prizzitano AM, Piluso GM, Iadevaio AL, Cinà MT, Cirrincione V, Gumina S, Codato G, Raimondo F, Capiello MG, Creta F, Barbieri M, Chiarella L, Abbondio L, Piccin M, Spillone V, Cutrupi G, Ruggeri A, Sicilia G, Provengano A, Marcari P, Ricci S, Pazzagli E, La Grotteria M, Orsini R, Leandri L, Vetere NA, Braggion E, Giordanino S, Armando S, Zampieri E, Danese MC, Valentini A, Ferrante MG, Santacroce C, Crocetti I, Macchi F, Bernacchi M, Pini D, Varì M, Lucente M, Scaramastra F, Reichardt S, Gabasio S, Zocchi C, Studhika M, Budzowska E, Cescon M, Lazzari D, Prizzon A, Di Biaggio P, Buda C, Mastrangelo V, Avigliano M, Dell'Aquila L, Bonanomi E, Mezzani A, Porcini F, Girardi G., PERRONE FILARDI, PASQUALE, Rete Infermieri GISSI, Hf, Di Giulio, P, Pera, C, Scarano, M, Ferri, B, Lepore, V, Miani, D, Tognoni, G, Rosson, V, Serafini, C, Zumino, Mt, Partemi, L, Falleroni, Ml, Moretti, L, Porta, L, Santorsola, A, Tenerelli, T, Bertoncelli, B, Mengoli, G, Stagnitto, M, Puddu, Gm, Masini, E, Pasini, A, Boni, S, Valsesia, E, Cornacini, G, Melis, D, Mulina, A, Giurlanda, A, Fava, M, Bellini, P, Vallucci, S, Cuomo, A, Campanale, S, Monatti, G, Bianco, T, Milli, V, Antonelli, L, Fanin, L, Faiola, L, Stefanizzi, R, Mariani, M, Rossi, A, Regnani, St, Loreni, F, Cianfrocca, R, Pisani, A, Faraolfi, V, Ponzalli, P, Savli, T, Cresci, M, Guardalben, S, Belluzzo, B, Ruberti, R, Zizzi, M, Tonda, C, Cadrobbi, Mg, Gilardi, R, Mondì, A, Costa, A, Milan, S, Zottarelli, A, Parodi, B, Sartorio, N, Rossin, B, Santi, A, Cagnan, P, Maradei, E, Cauteruccio, A, Carpino, C, Addeo, R, Izzo, A, Amendola, G, PERRONE FILARDI, Pasquale, Prizzitano, Am, Piluso, Gm, Iadevaio, Al, Cinà, Mt, Cirrincione, V, Gumina, S, Codato, G, Raimondo, F, Capiello, Mg, Creta, F, Barbieri, M, Chiarella, L, Abbondio, L, Piccin, M, Spillone, V, Cutrupi, G, Ruggeri, A, Sicilia, G, Provengano, A, Marcari, P, Ricci, S, Pazzagli, E, La Grotteria, M, Orsini, R, Leandri, L, Vetere, Na, Braggion, E, Giordanino, S, Armando, S, Zampieri, E, Danese, Mc, Valentini, A, Ferrante, Mg, Santacroce, C, Crocetti, I, Macchi, F, Bernacchi, M, Pini, D, Varì, M, Lucente, M, Scaramastra, F, Reichardt, S, Gabasio, S, Zocchi, C, Studhika, M, Budzowska, E, Cescon, M, Lazzari, D, Prizzon, A, Di Biaggio, P, Buda, C, Mastrangelo, V, Avigliano, M, Dell'Aquila, L, Bonanomi, E, Mezzani, A, Porcini, F, and Girardi, G.
Subjects: Depression, Patient Selection, Cardiology, Middle Aged, Prognosis, Nursing Research, Cognition, Italy, Surveys and Questionnaires, Quality of Life, Humans, Multicenter Studies as Topic, Cardiomyopathies, Geriatric Assessment, Aged, Randomized Controlled Trials as Topic
Abstract: To document the degree of reliability of validated and mainly qualitative questionnaires most often used in research settings and/or projects, in a broad network of unselected cardiological centres; to assess whether the quality of data could be compatible with their use not only as descriptive but also in prognostic scores including mainly "hard" clinical variables.Eighty-three patients were included. Compliance with the self-administration of the Kansas City Cardiomiopathy Questionnaire (KCCQ) and the Geriatric Depression Scale (GDS) was very high throughout the study (KCCQ 97.7% baseline and 85.8% at three years). As expected more difficulties were encountered with the Mini Mental State Examination (administered to 80.6% patients baseline and to 54.3% at three years). Main reasons for not administering questionnaires was ascribed to organizational and patients problems.It is worth noticing that the study was conducted by nurses without economical incentives. The questionnaires were well completed with minimal missing data. If questionnaires are well presented to patients, a routine assessment of quality of life and depression could be feasible in everyday care.
Published: 2009

15. [Quality of life, depression and cognitive functions 4. Quality of life]

Author: Rete Infermieri GISSI HF, Di Giulio P, Pera C, Scarano M, Ferri B, Lepore V, Miani D, Tognoni G, Rosson V, Serafini C, Zumino MT, Partemi L, Falleroni ML, Moretti L, Porta L, Santorsola A, Tenerelli T, Bertoncelli B, Mengoli G, Stagnitto M, Puddu GM, Masini E, Pasini A, Boni S, Valsesia E, Cornacini G, Melis D, Mulina A, Giurlanda A, Fava M, Bellini P, Vallucci S, Cuomo A, Campanale S, Monatti G, Bianco T, Milli V, Antonelli L, Fanin L, Faiola L, Stefanizzi R, Mariani M, Rossi A, Regnani ST, Loreni F, Cianfrocca R, Pisani A, Faraolfi V, Ponzalli P, Savli T, Cresci M, Guardalben S, Belluzzo B, Ruberti R, Zizzi M, Tonda C, Cadrobbi MG, Gilardi R, Mondì A, Costa A, Milan S, Zottarelli A, Parodi B, Sartorio N, Rossin B, Santi A, Cagnan P, Maradei E, Cauteruccio A, Carpino C, Addeo R, Izzo A, Amendola G, Prizzitano AM, Piluso GM, Iadevaio AL, Cinà MT, Cirrincione V, Gumina S, Codato G, Raimondo F, Capiello MG, Creta F, Barbieri M, Chiarella L, Abbondio L, Piccin M, Spillone V, Cutrupi G, Ruggeri A, Sicilia G, Provengano A, Marcari P, Ricci S, Pazzagli E, La Grotteria M, Orsini R, Leandri L, Vetere NA, Braggion E, Giordanino S, Armando S, Zampieri E, Danese MC, Valentini A, Ferrante MG, Santacroce C, Crocetti I, Macchi F, Bernacchi M, Pini D, Varì M, Lucente M, Scaramastra F, Reichardt S, Gabasio S, Zocchi C, Studhika M, Budzowska E, Cescon M, Lazzari D, Prizzon A, Di Baggio P, Buda C, Mastrangelo V, Avigliano M, Dell'Aquila L, Bonanomi E, Mezzani A, Porcini F, Girardi G., PERRONE FILARDI, PASQUALE, Rete Infermieri GISSI, Hf, Di Giulio, P, Pera, C, Scarano, M, Ferri, B, Lepore, V, Miani, D, Tognoni, G, Rosson, V, Serafini, C, Zumino, Mt, Partemi, L, Falleroni, Ml, Moretti, L, Porta, L, Santorsola, A, Tenerelli, T, Bertoncelli, B, Mengoli, G, Stagnitto, M, Puddu, Gm, Masini, E, Pasini, A, Boni, S, Valsesia, E, Cornacini, G, Melis, D, Mulina, A, Giurlanda, A, Fava, M, Bellini, P, Vallucci, S, Cuomo, A, Campanale, S, Monatti, G, Bianco, T, Milli, V, Antonelli, L, Fanin, L, Faiola, L, Stefanizzi, R, Mariani, M, Rossi, A, Regnani, St, Loreni, F, Cianfrocca, R, Pisani, A, Faraolfi, V, Ponzalli, P, Savli, T, Cresci, M, Guardalben, S, Belluzzo, B, Ruberti, R, Zizzi, M, Tonda, C, Cadrobbi, Mg, Gilardi, R, Mondì, A, Costa, A, Milan, S, Zottarelli, A, Parodi, B, Sartorio, N, Rossin, B, Santi, A, Cagnan, P, Maradei, E, Cauteruccio, A, Carpino, C, Addeo, R, Izzo, A, Amendola, G, PERRONE FILARDI, Pasquale, Prizzitano, Am, Piluso, Gm, Iadevaio, Al, Cinà, Mt, Cirrincione, V, Gumina, S, Codato, G, Raimondo, F, Capiello, Mg, Creta, F, Barbieri, M, Chiarella, L, Abbondio, L, Piccin, M, Spillone, V, Cutrupi, G, Ruggeri, A, Sicilia, G, Provengano, A, Marcari, P, Ricci, S, Pazzagli, E, La Grotteria, M, Orsini, R, Leandri, L, Vetere, Na, Braggion, E, Giordanino, S, Armando, S, Zampieri, E, Danese, Mc, Valentini, A, Ferrante, Mg, Santacroce, C, Crocetti, I, Macchi, F, Bernacchi, M, Pini, D, Varì, M, Lucente, M, Scaramastra, F, Reichardt, S, Gabasio, S, Zocchi, C, Studhika, M, Budzowska, E, Cescon, M, Lazzari, D, Prizzon, A, Di Baggio, P, Buda, C, Mastrangelo, V, Avigliano, M, Dell'Aquila, L, Bonanomi, E, Mezzani, A, Porcini, F, and Girardi, G.
Subjects: Male, Depression, Cardiology, Prognosis, Hospitalization, Nursing Research, Cognition, Italy, Risk Factors, Data Interpretation, Statistical, Surveys and Questionnaires, Quality of Life, Humans, Female, Mortality, Cardiomyopathies, Aged, Randomized Controlled Trials as Topic
Abstract: Aim of this paper is to explore and quanti-quantitatively assess whether QoL as measured with the Kansas City Cardiomiopathy Questionnaire (KCCQ) summary score could be considered as an independent relevant component of clinical prognostic score of morbidity and mortality and identify patients at risk for death or admissions.Sixty-three per cent NYHA II and 39.4% NYHA III-IV patients experience a good Qol (score75). Risk factors for "not good" (75) QoL are age, NYHA class III-IV, diabetes, COPD and previous hospitalizations. NYHA II and III-IV patients with not good QoL experience an higher mortality than patients with a good QoL in the same classes. NYHA II patients with not good QoL experience the same 1 year readmission rates as NYHA III-IV patients with good QoL.Quality of life scores identify patients with different risk of mortality and readmissions within the same NYHA class. The prognostic value of KCCQ summary scores could identify candidates for disease management in whom better targeted care strategies may reduce hospitalizations and prevent deaths.
Published: 2009

16. [Quality of life, depression and cognitive functions 3. The main characteristics of the QDF study population]

Author: Rete Infermieri GISSI HF, Di Giulio P, Pera C, Scarano M, Ferri B, Lepore V, Miani D, Tognoni G, Rosson V, Serafini C, Zumino MT, Partemi L, Falleroni ML, Moretti L, Porta L, Santorsola A, Tenerelli T, Bertoncelli B, Mengoli G, Stagnitto M, Puddu GM, Masini E, Pasini A, Boni S, Valsesia E, Cornacini G, Melis D, Mulina A, Giurlanda A, Fava M, Bellini P, Vallucci S, Cuomo A, Campanale S, Monatti G, Bianco T, Milli V, Antonelli L, Fanin L, Faiola L, Stefanizzi R, Mariani M, Rossi A, Regnani ST, Loreni F, Cianfrocca R, Pisani A, Faraolfi V, Ponzalli P, Savli T, Cresci M, Guardalben S, Belluzzo B, Ruberti R, Zizzi M, Tonda C, Cadrobbi MG, Gilardi R, Mondì A, Costa A, Milan S, Zottarelli A, Parodi B, Sartorio N, Rossin B, Santi A, Cagnan P, Maradei E, Cauteruccio A, Carpino C, Addeo R, Izzo A, Amendola G, Prizzitano AM, Piluso GM, Iadevaio AL, Cinà MT, Cirrincione V, Gumina S, Codato G, Raimondo F, Cappiello MG, Creta F, Barbieri M, Chiarella L, Abbondio L, Piccin M, Spillone V, Cutrupi G, Ruggeri A, Sicilia G, Provengano A, Marcari P, Ricci S, Pazzagli E, La Grotteria M, Orsini R, Leandri L, Vetere NA, Braggion E, Giordanino S, Armando S, Zampieri E, Danese MC, Valentini A, Ferrante MG, Santacroce C, Crocetti I, Macchi F, Bernacchi M, Pini D, Varì M, Lucente M, Scaramastra F, Reichardt S, Gabasio S, Zocchi C, Studhika M, Budzowska E, Cescon M, Lazzari D, Prizzon A, Di Biaggio P, Buda C, Mastrangelo V, Avigliano M, Dell'Aquila L, Bonanomi E, Mezzani A, Porcini F, Girardi G., PERRONE FILARDI, PASQUALE, Rete Infermieri GISSI, Hf, Di Giulio, P, Pera, C, Scarano, M, Ferri, B, Lepore, V, Miani, D, Tognoni, G, Rosson, V, Serafini, C, Zumino, Mt, Partemi, L, Falleroni, Ml, Moretti, L, Porta, L, Santorsola, A, Tenerelli, T, Bertoncelli, B, Mengoli, G, Stagnitto, M, Puddu, Gm, Masini, E, Pasini, A, Boni, S, Valsesia, E, Cornacini, G, Melis, D, Mulina, A, Giurlanda, A, Fava, M, Bellini, P, Vallucci, S, Cuomo, A, Campanale, S, Monatti, G, Bianco, T, Milli, V, Antonelli, L, Fanin, L, Faiola, L, Stefanizzi, R, Mariani, M, Rossi, A, Regnani, St, Loreni, F, Cianfrocca, R, Pisani, A, Faraolfi, V, Ponzalli, P, Savli, T, Cresci, M, Guardalben, S, Belluzzo, B, Ruberti, R, Zizzi, M, Tonda, C, Cadrobbi, Mg, Gilardi, R, Mondì, A, Costa, A, Milan, S, Zottarelli, A, Parodi, B, Sartorio, N, Rossin, B, Santi, A, Cagnan, P, Maradei, E, Cauteruccio, A, Carpino, C, Addeo, R, Izzo, A, Amendola, G, PERRONE FILARDI, Pasquale, Prizzitano, Am, Piluso, Gm, Iadevaio, Al, Cinà, Mt, Cirrincione, V, Gumina, S, Codato, G, Raimondo, F, Cappiello, Mg, Creta, F, Barbieri, M, Chiarella, L, Abbondio, L, Piccin, M, Spillone, V, Cutrupi, G, Ruggeri, A, Sicilia, G, Provengano, A, Marcari, P, Ricci, S, Pazzagli, E, La Grotteria, M, Orsini, R, Leandri, L, Vetere, Na, Braggion, E, Giordanino, S, Armando, S, Zampieri, E, Danese, Mc, Valentini, A, Ferrante, Mg, Santacroce, C, Crocetti, I, Macchi, F, Bernacchi, M, Pini, D, Varì, M, Lucente, M, Scaramastra, F, Reichardt, S, Gabasio, S, Zocchi, C, Studhika, M, Budzowska, E, Cescon, M, Lazzari, D, Prizzon, A, Di Biaggio, P, Buda, C, Mastrangelo, V, Avigliano, M, Dell'Aquila, L, Bonanomi, E, Mezzani, A, Porcini, F, and Girardi, G.
Subjects: Aged, 80 and over, Male, Depression, Age Factors, Cardiology, Prognosis, Education, Nursing Research, Cognition, Sex Factors, Italy, Surveys and Questionnaires, Quality of Life, Humans, Female, Cardiomyopathies, Aged, Randomized Controlled Trials as Topic
Abstract: This contribution describes the patients included for the QDF (Quality of life, Depression and Cognitive functions) study and explores the distribution and time trends of scores of the three dimensions.The large majority of patients are males (78.3%), and mean age is 67.2 +/- 10.7 years (9.2%80 years). Patients in NYHA class III-IV experience more depression and a worse QoL as compared to the less severly clinically affected counterparts in NYHA class. Although QoL and depression are influenced by the same variables, not all patients with bad QoL are depressed and viceversa. Mean scores of cognitive functioning are not influenced by the same variables that influence QoL and depression.The regular measurement of QoL, depression and cognitive function is recommended by some authors. It seems to be confirmed that the three dimensions need to be explored to disentangle the specific informative value that each of them could add to clinical measures.
Published: 2009

17. [Quality of life, depression and cognitive functions 6. Cognitive functions]

Author: Rete Infermieri GISSI HF, Di Giulio P, Pera C, Scarano M, Ferri B, Lepore V, Miani D, Tognoni G, Rosson V, Serafini C, Zumino MT, Partemi L, Falleroni ML, Moretti L, Porta L, Santorsola A, Tenerelli T, Bertoncelli B, Mengoli G, Stagnitto M, Puddu GM, Masini E, Pasini A, Boni S, Valsesia E, Cornacini G, Melis D, Mulina A, Giurlanda A, Fava M, Bellini P, Vallucci S, Cuomo A, Campanale S, Monatti G, Bianco T, Milli V, Antonelli L, Fanin L, Faiola L, Stefanizzi R, Mariani M, Rossi A, Regnani ST, Loreni F, Cianfrocca R, Pisani A, Faraolfi V, Ponzalli P, Savli T, Cresci M, Guardalben S, Belluzzo B, Ruberti R, Zizzi M, Tonda C, Cadrobbi MG, Gilardi R, Mondì A, Costa A, Milan S, Zottarelli A, Parodi B, Sartorio N, Rossin B, Santi A, Cagnan P, Maradei E, Cauteruccio A, Carpino C, Addeo R, Izzo A, Amendola G, Prizzitano AM, Piluso GM, Iadevaio AL, Cinà MT, Cirrincione V, Gumina S, Codato G, Raimondo F, Cappiello MG, Creta F, Barbieri M, Chiarella L, Abbondio L, Piccin M, Spillone V, Cutrupi G, Ruggeri A, Sicilia G, Provengano A, Marcari P, Ricci S, Pazzagli E, La Grotteria M, Orsini R, Leandri L, Vetere NA, Braggion E, Giordanino S, Armando S, Zampieri E, Danese MC, Valentini A, Ferrante MG, Santacroce C, Crocetti I, Macchi F, Bernacchi M, Pini D, Varì M, Lucente M, Scaramastra F, Reichardt S, Gabasio S, Zocchi C, Studhika M, Budzowska E, Cescon M, Lazzari D, Prizzon A, Di Biaggio P, Buda C, Mastrangelo V, Avigliano M, Dell'Aquila L, Bonanomi E, Mezzani A, Porcini F, Girardi G., PERRONE FILARDI, PASQUALE, Rete Infermieri GISSI, Hf, Di Giulio, P, Pera, C, Scarano, M, Ferri, B, Lepore, V, Miani, D, Tognoni, G, Rosson, V, Serafini, C, Zumino, Mt, Partemi, L, Falleroni, Ml, Moretti, L, Porta, L, Santorsola, A, Tenerelli, T, Bertoncelli, B, Mengoli, G, Stagnitto, M, Puddu, Gm, Masini, E, Pasini, A, Boni, S, Valsesia, E, Cornacini, G, Melis, D, Mulina, A, Giurlanda, A, Fava, M, Bellini, P, Vallucci, S, Cuomo, A, Campanale, S, Monatti, G, Bianco, T, Milli, V, Antonelli, L, Fanin, L, Faiola, L, Stefanizzi, R, Mariani, M, Rossi, A, Regnani, St, Loreni, F, Cianfrocca, R, Pisani, A, Faraolfi, V, Ponzalli, P, Savli, T, Cresci, M, Guardalben, S, Belluzzo, B, Ruberti, R, Zizzi, M, Tonda, C, Cadrobbi, Mg, Gilardi, R, Mondì, A, Costa, A, Milan, S, Zottarelli, A, Parodi, B, Sartorio, N, Rossin, B, Santi, A, Cagnan, P, Maradei, E, Cauteruccio, A, Carpino, C, Addeo, R, Izzo, A, Amendola, G, PERRONE FILARDI, Pasquale, Prizzitano, Am, Piluso, Gm, Iadevaio, Al, Cinà, Mt, Cirrincione, V, Gumina, S, Codato, G, Raimondo, F, Cappiello, Mg, Creta, F, Barbieri, M, Chiarella, L, Abbondio, L, Piccin, M, Spillone, V, Cutrupi, G, Ruggeri, A, Sicilia, G, Provengano, A, Marcari, P, Ricci, S, Pazzagli, E, La Grotteria, M, Orsini, R, Leandri, L, Vetere, Na, Braggion, E, Giordanino, S, Armando, S, Zampieri, E, Danese, Mc, Valentini, A, Ferrante, Mg, Santacroce, C, Crocetti, I, Macchi, F, Bernacchi, M, Pini, D, Varì, M, Lucente, M, Scaramastra, F, Reichardt, S, Gabasio, S, Zocchi, C, Studhika, M, Budzowska, E, Cescon, M, Lazzari, D, Prizzon, A, Di Biaggio, P, Buda, C, Mastrangelo, V, Avigliano, M, Dell'Aquila, L, Bonanomi, E, Mezzani, A, Porcini, F, and Girardi, G.
Subjects: Aged, 80 and over, Heart Failure, Male, Time Factors, Depression, Cardiology, Prognosis, Education, Hospitalization, Nursing Research, Sex Factors, Italy, Risk Factors, Prevalence, Quality of Life, Humans, Female, Mortality, Cognition Disorders, Aged, Randomized Controlled Trials as Topic
Abstract: The prevalence of cognitive impairment (CI) is reported to be higher in heart failure patients than in the general population.To describe the prevalence of CI and to assess its prognostic value on the increased risk of hospitalizations and death over the medium term (3 years).MMSE was administered to 620/745 heart failure patients70 years. Up to 35% of the tested population were classified as mild CI and 12% as moderate. The severity of baseline clinical conditions, as expressed as NYHA classes, do not appear to be associated to different degrees of CI. The subgroup of patients with moderate CI includes higher proportion of people with the lowest educational level, of feminine gender, of higher age (80). Even in a population closely monitored as the one included in the GISSI-HLF trial, it is worth to be underlined that the presence of moderate CI appears to be strongly prognostic of an increased burden of care (hospitalizations), and of death over the whole observation period of the study (3 years).The presence of even mild or moderate CI is prognostic for increased mortality and readmissions for patients of the same NYHA class. In the absence of effective intervention strategies, research should concentrate on the yield, if any, of a systematic screening for CI in heart failure patients.
Published: 2009

18. [Quality of life, depression and cognitive functions 5. Depression]

Author: Rete Infermieri GISSI HF, Di Giulio P, Pera C, Scarano M, Ferri B, Lepore V, Miani D, Tognoni G, Rosson V, Serafini C, Zumino MT, Partemi L, Falleroni ML, Moretti L, Porta L, Santorsola A, Tenerelli T, Bertoncelli B, Mengoli G, Stagnitto M, Puddu GM, Masini E, Pasini A, Boni S, Valsesia E, Cornacini G, Melis D, Mulina A, Giurlanda A, Fava M, Bellini P, Vallucci S, Cuomo A, Campanale S, Monatti G, Bianco T, Milli V, Antonelli L, Fanin L, Faiola L, Stefanizzi R, Mariani M, Rossi A, Regnani ST, Loreni F, Cianfrocca R, Pisani A, Faraolfi V, Ponzalli P, Savli T, Cresci M, Guardalben S, Belluzzo B, Ruberti R, Zizzi M, Tonda C, Cadrobbi MG, Gilardi R, Mondì A, Costa A, Milan S, Zottarelli A, Parodi B, Sartorio N, Rossin B, Santi A, Cagnan P, Maradei E, Cauteruccio A, Carpino C, Addeo R, Izzo A, Amendola G, Prizzitano AM, Piluso GM, Iadevaio AL, Cinà MT, Cirrincione V, Gumina S, Codato G, Raimondo F, Cappiello MG, Creta F, Barbieri M, Chiarella L, Abbondio L, Piccin M, Spillone V, Cutrupi G, Ruggeri A, Sicilia G, Provengano A, Marcari P, Ricci S, Pazzagli E, La Grotteria M, Orsini R, Leandri L, Vetere NA, Braggion E, Giordanino S, Armando S, Zampieri E, Danese MC, Valentini A, Ferrante MG, Santacroce C, Crocetti I, Macchi F, Bernacchi M, Pini D, Varì M, Lucente M, Scaramastra F, Reichardt S, Gabasio S, Zocchi C, Studhika M, Budzowska E, Cescon M, Lazzari D, Prizzon A, Di Biaggio P, Buda C, Mastrangelo V, Avigliano M, Dell'Aquila L, Bonanomi E, Mezzani A, Porcini F, Girardi G., PERRONE FILARDI, PASQUALE, Rete Infermieri GISSI, Hf, Di Giulio, P, Pera, C, Scarano, M, Ferri, B, Lepore, V, Miani, D, Tognoni, G, Rosson, V, Serafini, C, Zumino, Mt, Partemi, L, Falleroni, Ml, Moretti, L, Porta, L, Santorsola, A, Tenerelli, T, Bertoncelli, B, Mengoli, G, Stagnitto, M, Puddu, Gm, Masini, E, Pasini, A, Boni, S, Valsesia, E, Cornacini, G, Melis, D, Mulina, A, Giurlanda, A, Fava, M, Bellini, P, Vallucci, S, Cuomo, A, Campanale, S, Monatti, G, Bianco, T, Milli, V, Antonelli, L, Fanin, L, Faiola, L, Stefanizzi, R, Mariani, M, Rossi, A, Regnani, St, Loreni, F, Cianfrocca, R, Pisani, A, Faraolfi, V, Ponzalli, P, Savli, T, Cresci, M, Guardalben, S, Belluzzo, B, Ruberti, R, Zizzi, M, Tonda, C, Cadrobbi, Mg, Gilardi, R, Mondì, A, Costa, A, Milan, S, Zottarelli, A, Parodi, B, Sartorio, N, Rossin, B, Santi, A, Cagnan, P, Maradei, E, Cauteruccio, A, Carpino, C, Addeo, R, Izzo, A, Amendola, G, PERRONE FILARDI, Pasquale, Prizzitano, Am, Piluso, Gm, Iadevaio, Al, Cinà, Mt, Cirrincione, V, Gumina, S, Codato, G, Raimondo, F, Cappiello, Mg, Creta, F, Barbieri, M, Chiarella, L, Abbondio, L, Piccin, M, Spillone, V, Cutrupi, G, Ruggeri, A, Sicilia, G, Provengano, A, Marcari, P, Ricci, S, Pazzagli, E, La Grotteria, M, Orsini, R, Leandri, L, Vetere, Na, Braggion, E, Giordanino, S, Armando, S, Zampieri, E, Danese, Mc, Valentini, A, Ferrante, Mg, Santacroce, C, Crocetti, I, Macchi, F, Bernacchi, M, Pini, D, Varì, M, Lucente, M, Scaramastra, F, Reichardt, S, Gabasio, S, Zocchi, C, Studhika, M, Budzowska, E, Cescon, M, Lazzari, D, Prizzon, A, Di Biaggio, P, Buda, C, Mastrangelo, V, Avigliano, M, Dell'Aquila, L, Bonanomi, E, Mezzani, A, Porcini, F, and Girardi, G.
Subjects: Male, Time Factors, Depression, Health Status, Cardiology, Patient Readmission, Hospitalization, Nursing Research, Cognition, Sex Factors, Italy, Risk Factors, Data Interpretation, Statistical, Prevalence, Quality of Life, Humans, Female, Mortality, Geriatric Assessment, Aged, Randomized Controlled Trials as Topic
Abstract: Depression is common in patients with heart failure but its causal and/or prognostic role with respect to the cardiac condition in still a matter of research.To describe the prevalence of depression and to assess its specific prognostic value in terms of increased risk of hospitalizations or death.Overall, 27.5% of 1495 patients experience symptoms of depression. Risk factors for depression are female sex, age70, higher NYHA class, previous hospitalizations and comorbidities. Depressed patients of the same NYHA class are at higher risk for 1 and 3 years mortality and all causes hospital admissions.Depression, assessed with a simple and easy to administer instrument, can add information to clinical variables in the identification of patients at increased risk of mortality and readmissions within the same NYHA class.
Published: 2009

19. Safety, efficacy, and tolerability of differential treatment to prevent and treat vaginal dryness and vulvovaginitis in diabetic women

Author: Carati, D., primary, Zizza, A., primary, Guido, M., primary, Donno, A. De, primary, Stefanizzi, R., primary, Serra, R., primary, Romano, I., primary, Ouedraogo, C., primary, Megha, M., primary, and Tinelli, A., primary
Published: 2016
Full Text: View/download PDF

20. Study on cosmogenic activation above ground for the DarkSide-20k project

Author: Aaron, E., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Atzori Corona, M., Ave, M., Avetisov, I. Ch, Azzolini, O., Back, H. O., Balmforth, Z., Barrado-Olmedo, A., Barrillon, P., Basco, A., Batignani, G., Bocci, V., Bonivento, W. M., Bottino, B., Boulay, M. G., Busto, J., Cadeddu, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Nicola Cargioli, Carlini, M., Castello, P., Cavalcante, P., Cavuoti, S., Cebrian, S., Ruiz, J. M. Cela, Chashin, S., Chepurnov, A., Chyhyrynets, E., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Cocco, V., Vilda, E. Conde, Consiglio, L., Copello, S., Covone, G., Czubak, M., D Aniello, M., D Auria, S., Da Rocha Rolo, M. D., Davini, S., Cecco, S., Gruttola, D., Pasquale, S., Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dolganov, G., Dordei, F., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Fiorillo, G., Franchini, P., Franco, D., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gendotti, A., Ghiano, C., Giganti, C., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grauso, G., Di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A. L., Hamer, A., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hucker, J., Hugues, T., Ianni, An, Ippolito, V., Jillings, C., Jois, S., Kachru, P., Kemp, A. A., Kendziora, C. L., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., La Commara, M., Lai, M., Le Guirriec, E., Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Margotti, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., Mcdonald, A. B., Messina, A., Milincic, R., Mitra, A., Moharana, A., Monroe, J., Moretti, E., Morrocchi, M., Mróz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Nessi, M., Nikolopoulos, K., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., Solórzano, A. Ortiz, Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pellegrino, C., Pesudo, V., Piacentini, S., Pietrofaccia, L., Pino, N., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Ragusa, F., Ramachers, Y., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sabia, M. A., Salomone, P., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schillaci, G., Schuckman, Ii F. G., Scioli, G., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Tricomi, A., Unzhakov, E. V., John, T. Vallivilayil, Uffelen, M., Viant, T., Viel, S., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wingerter-Seez, I., Wojaczynski, R., Wojcik, Ma M., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., Zykova, M. P., Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), and DarkSide-20k
Subjects: Physics - Instrumentation and Detectors, long-lived, FOS: Physical sciences, instrumentation and detectors, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), iron, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], surface, High Energy Physics, titanium, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], time projection chamber, liquid argon, Instrumentation and Methods for Astrophysics (astro-ph.IM), galaxy, dark matter, astro-ph.IM, experiment, physics, background, Instrumentation and Detectors (physics.ins-det), cosmic radiation, copper, argon, direct detection, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: The activation of materials due to exposure to cosmic rays may become an important background source for experiments investigating rare event phenomena. DarkSide-20k, currently under construction at the Laboratori Nazionali del Gran Sasso, is a direct detection experiment for galactic dark matter particles, using a two-phase liquid-argon Time Projection Chamber (TPC) filled with 49.7 tonnes (active mass) of Underground Argon (UAr) depleted in 39Ar. Despite the outstanding capability of discriminating gamma/beta background in argon TPCs, this background must be considered because of induced dead time or accidental coincidences mimicking dark-matter signals and it is relevant for low-threshold electron-counting measurements. Here, the cosmogenic activity of relevant long-lived radioisotopes induced in the experiment has been estimated to set requirements and procedures during preparation of the experiment and to check that it is not dominant over primordial radioactivity; particular attention has been paid to the activation of the 120 t of UAr used in DarkSide-20k. Expected exposures above ground and production rates, either measured or calculated, have been considered in detail. From the simulated counting rates in the detector due to cosmogenic isotopes, it is concluded that activation in copper and stainless steel is not problematic. The activity of 39Ar induced during extraction, purification and transport on surface is evaluated to be 2.8% of the activity measured in UAr by DarkSide-50 experiment, which used the same underground source, and thus considered acceptable. Other isotopes in the UAr such as 37Ar and 3H are shown not to be relevant due to short half-life and assumed purification methods., Comment: As accepted for publication at Astroparticle Physics

21. Safety, efficacy, and tolerability of differential treatment to prevent and treat vaginal dryness and vulvovaginitis in diabetic women

Author: A. De Donno, R Serra, Andrea Tinelli, R Stefanizzi, Marcella Megha, Davide Carati, I Romano, Antonella Zizza, Marcello Guido, C Ouedraogo, Carati, D., Zizza, Antonella, Guido, Marcello, DE DONNO, Maria Antonella, Stefanizzi, R., Serra, R., Romano, I., Ouedraogo, C., Megha, M., and Tinelli, A.
Subjects: Adult, Glycerol, medicine.medical_specialty, 030209 endocrinology & metabolism, Pharmacology, Pantothenic Acid, law.invention, Diabetes Complications, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Recurrence, Internal medicine, Diabetes mellitus, medicine, Diabetes Mellitus, Humans, Single-Blind Method, ortho-Aminobenzoates, Lactic Acid, Hyaluronic Acid, Recurrent candida infections, Candidiasis, Vulvovaginal, Vaginal dryness, 030219 obstetrics & reproductive medicine, Differential treatment, Viscosupplements, business.industry, Significant difference, Vaginal gel, Obstetrics and Gynecology, Middle Aged, medicine.disease, Vulvovaginitis, Lipids, Administration, Intravaginal, Drug Combinations, Dyspareunia, Reproductive Medicine, Tolerability, Vaginal Creams, Foams, and Jellies, Female, business
Abstract: Background Problems affecting the vaginal tract in diabetic women are very often neglected. The efficacy and safety of three gynecological treatments in diabetic women have been assessed. Materials and methods A single-blind randomized progressive trial on 48 diabetic women affected by vaginal dryness, dyspareunia, and recurrent Candida infections was carried out. The ICIQ Vaginal Symptoms (ICIQ-VS) questionnaire was administered. Results The analysis of the parameters of ICIQ-VS questionnaire among the three groups showed significant difference only for "dragging pain" (p = 0.0 19) and "soreness" (p = 0.028). In all groups and for all parameters of the questionnaire, improvement of symptoms was observed. In particular, in Group 1 for all symptoms a highly significant difference was observed, to support the already known benefits of the products and of the proposed combination. Significant improvement was also observed in Group 2. Conclusions The proposed treatment with DermoXEN® Ultracalming Special for diabetics and DermoXEN® Vitexyl vaginal gel exert effective moisturizing and soothing action. Indeed, the aforementioned products have been proven effective for the main gynecological problems of diabetic women.
Published: 2016

22. Long-Term Analysis of Respiratory-Related Complications Following Gastrostomy Placement with or without Fundoplication in Neurologically Impaired Children: A Retrospective Cohort Study.

Author: Zambaiti E, Virgone C, Bisoffi S, Stefanizzi R, Fascetti Leon F, and Gamba P
Abstract: Gastrostomy placement is crucial in neurologically impaired (NI) children to ensure an adequate food intake and a safe route for drugs administration and to reduce the risk of primary aspiration. NI patents are more prone to gastroesophageal reflux. The association with fundoplication is deemed to reduce reflux-related respiratory complications. However, long-term benefits of this approach are not clear. We therefore aimed to compare long-term reflux-related respiratory complications of gastrostomy only (GO) to gastrostomy with fundoplication (GF). We retrospectively reviewed 145 consecutive NI children managed from 2008 to 2018. As long-term outcomes, we analyzed number and length of hospital admissions (Reflux-Related-Hospitalization, RRH) and emergency department accesses (Reflux-Related-Accesses, RRA) due to respiratory problems. Results were analyzed with appropriate statistical method. Median age at referral and at gastrostomy placement were 2.2 and 3.4 years (SD 5.6), respectively. Median follow-up was four years (range 1-12). Anti-reflux procedures were performed in 26/145 patients (18%); tracheotomy in 23/145 (16%). RRH following surgery showed lower number of admissions/year (0.32 vs. 1 for GO vs. GF, p < 0.005) and days hospitalization/year (3 vs. 13, p = 0.08) in GO compared to GF; RRA was similar (0.60 vs. 0.65, p = 0.43). Gastrostomy placement alone appeared not to be inferior to gastrostomy plus fundoplication with respect to long-term respiratory-related outcomes for NI children in our center.
Published: 2021
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1. Benchmarking the design of the cryogenics system for the underground argon in DarkSide-20k

2. DarkSide-20k sensitivity to light dark matter particles

3. A new hybrid gadolinium nanoparticles-loaded polymeric material for neutron detection in rare event searches

4. Directionality of nuclear recoils in a liquid argon time projection chamber

5. Sensitivity projections for a dual-phase argon TPC optimized for light dark matter searches through the ionization channel

6. Separating $^{39}$Ar from $^{40}$Ar by cryogenic distillation with Aria for dark matter searches

7. Study of cosmogenic activation above ground for the DarkSide-20k experiment

8. Measurement of isotopic separation of argon with the prototype of the cryogenic distillation plant Aria for dark matter searches

9. The European Physical Journal C

10. Separating $^{39}$Ar from $^{40}$Ar by cryogenic distillation with Aria for dark matter searches

12. P011 Just a spoonful of sugar helps the medicine go down: L-arginine pill related esophageal ulcer, the first pediatric case report

13. [Quality of life, depression and cognitive functions 1. Operational protocol and its implementation]

14. [Quality of life, depression and cognitive functions 2. Methodological aspects and data quality]

15. [Quality of life, depression and cognitive functions 4. Quality of life]

16. [Quality of life, depression and cognitive functions 3. The main characteristics of the QDF study population]

17. [Quality of life, depression and cognitive functions 6. Cognitive functions]

18. [Quality of life, depression and cognitive functions 5. Depression]

19. Safety, efficacy, and tolerability of differential treatment to prevent and treat vaginal dryness and vulvovaginitis in diabetic women

20. Study on cosmogenic activation above ground for the DarkSide-20k project

21. Safety, efficacy, and tolerability of differential treatment to prevent and treat vaginal dryness and vulvovaginitis in diabetic women

22. Long-Term Analysis of Respiratory-Related Complications Following Gastrostomy Placement with or without Fundoplication in Neurologically Impaired Children: A Retrospective Cohort Study.

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