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Your search keyword '"Stefanovic, Igor"' showing total 27 results
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27 results on '"Stefanovic, Igor"'

1. Correlation of Near-Infrared Spectroscopy (NIRS) with Invasive Arterial Pressure Monitoring during Aortic Coarctation Surgery in Pediatric Patients.

Author

Pjevalica Dragic, Jelena, Zecevic, Tatjana, Divac, Ivan, Pavlovic, Andrija, Bisenic, Dejan, Stanisic, Luka, Kalanj, Jasna, Stefanovic, Igor, Nikolic, Dejan, Petrov, Ivana, and Milovanovic, Vladimir

Subjects
PEARSON correlation (Statistics), RESEARCH funding, AORTIC coarctation, NEAR infrared spectroscopy, RETROSPECTIVE studies, DESCRIPTIVE statistics, ARTERIAL pressure, PEDIATRICS, LONGITUDINAL method, MEDICAL records, ACQUISITION of data, DATA analysis software, COMORBIDITY, CHILDREN
Abstract

Aortic coarctation surgery in pediatric patients requires the placement of two arterial cannulas to monitor pressure gradients and surgical correction adequacy. Near-infrared spectroscopy (NIRS) monitoring provides insight into regional blood flow. This study aimed to investigate the correlation between NIRS values and invasive arterial pressures, exploring NIRS monitoring as a potential substitute for arterial cannulation. In a cohort of 21 consecutive pediatric patients undergoing aortic coarctation surgery, recordings of NIRS and invasive arterial pressure values were evaluated at various time intervals. Pearson correlation evaluated the relationship between NIRS values and invasively measured arterial pressures. Moderate to strong correlations were observed between the mean arterial pressure (MAP) of the upper and lower arteries and cerebral (rSO2-C) and somatic (rSO2-S) NIRS values 5 min after cross-clamp placement (r = 0.621, p = 0.003; r = 0.757, p < 0.001). Strong correlations were found 15 min after cross-clamp placement (r = 0.828, p = 0.002; r = 0.783, p = 0.004). Before transfer to the ICU, a strong correlation existed between the upper artery MAP and rSO2-C (r = 0.730, p < 0.001), but there was no correlation between the lower artery MAP and rSO2-S. These findings are promising, but further studies are required to validate it as a reliable substitute for invasive pressure monitoring in this patient population. [ABSTRACT FROM AUTHOR]

Published
2024
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2. Clinical and Hemodynamic Outcomes with Enalapril Orodispersible Minitablets in Young Children with Heart Failure Due to Congenital Heart Disease.

Author

Bijelic, Maja, Djukic, Milan, Vukomanovic, Vladislav, Parezanovic, Vojislav, Lazic, Milica, Pavlovic, Andrija, Popovic, Sasa, Parezanovic, Miro, Stefanovic, Igor, Djordjevic, Stefan, Ninic, Sanja, Prijic, Sergej, Bozic Cvijan, Bojana, Jovanovic, Ida, and Bajcetic, Milica

Subjects
CONGENITAL heart disease, SYSTOLIC blood pressure, ACE inhibitors, CHILD patients, HEART failure
Abstract

Background: The angiotensin-converting enzyme inhibitor (ACEI) enalapril is often administered to infants and young children with heart failure (HF) in various dosing regimens and formulations not adapted for their age. Methods: This prospective, two-center, open-label 8-week study evaluated an age-appropriate formulation of orodispersible minitablets (ODMTs) of enalapril (0.25 mg and 1 mg) in children aged 0 to 6 years with HF due to congenital heart disease. An age/weight-based dosing schedule was followed. Measures of echocardiographic parameters, blood pressure, heart rate, modified Ross score, and biochemistry were obtained over the 8-week period. The following two groups were assessed: ACEI-naïve and ACEI-pretreated patients. Results: In total, 53 children (age range of 0.05 to 4.8 years) were enrolled and 29 were ACEI-naïve. The average enalapril dose was 0.098 mg/kg (0.06–0.17 mg/kg) in the naïve group and 0.15 mg/kg (0.07–0.3 mg/kg) in pretreated patients. After 8 weeks, the modified Ross score and left ventricular diastolic dimension (LVD) z-score showed a significant decrease in both groups (p < 0.005). During 8 weeks follow-up, there were no difference in the z-scores for the systolic blood pressure (p = 0.071) or heart rate (p = 0.146). Conclusions: Pediatric patients treated with ODMTs of enalapril for 8 weeks had favorable improvements in LVD and HF symptoms. [ABSTRACT FROM AUTHOR]

Published
2024
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3. A quality control system for ligand-binding assay of plasma renin activity: Proof-of-concept within a pharmacodynamic study

Author

Läer, Stephanie, Breitkreutz, Jörg, Klingmann, Ingrid, Lagler, Florian, de Hoon, Jan, Dalinghaus, Michiel, Bajcetic, Milica, de Wildt, Saskia, Clarke, Anne Keatley, Breur, Johannes, Male, Christoph, Ablonczy, Laslo, Mir, Thomas, Vukomanovic, Vladislav, Dukic, Milan, Jovanovic, Ida, Burckhardt, Bjoern B., Cawello, Willi, Kleine, Karl, Moder, Angelika, Obarcanin, Emina, Wagner, Peter, Walsh, Jennifer, van Hecken, Anne, Spatenkova, Lucie, Ali, Mohsin, Božić, Bojana, Burdman, Maja Bijelić Ilja, Ciplea, Agnes, Faisal, Muhammad, Farahani, Samieh, Feickert, Martin, Gangnus, Tanja, Lazic, Milica, Makowski, Nina, Suessenbach, Fabian, van der Meulen, Marijke, Popović, Saša, Parezanović, Miro, Smeets, Nori, Swoboda, Vanessa, Bojanin, Dragana, Đorđević, Stefan, Dragić, Jasminka, Holle, Ann-Kathrin, Jovičić, Bosiljka, Košutić, Jovan, Kozomara, Gordana, Majid, Haidara, Mitrović, Jadranka, Ninić, Sanja, Parezanovic, Miro, Parezanovic, Vojislav, Pavlović, Andrija, Prijić, Sergej, Rebić, Branislava, Stefanović, Igor, Tordas, Daniel, Vulićević, Irena, Bartels, Anke, Čeko, Andjelka, Herborts, Marissa, Hennink, Annelies, Kosanović, Bosiljka, Kostic, Sanja, Isailović, Ljiljana, Maksimovic, Jasmina, Manai, Badies, Martinović, Nada, Máté, Gyöngyi, Perišić, Miloš, Reljić, Jelena, Salamomovic, Regina Pirker Marta, Schlesner, Claudia, Tins, Jutta, Wissmann, Eva, Suessenbach, Fabian Konstantin, and Burckhardt, Bjoern Bengt

Published
2020
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4. Immediate results of primary balloon dilation for congenital aortic valve stenosis predict the mid-term outcome

Author

Pavlovic, Andrija, primary, Parezanovic, Vojislav, additional, Stefanovic, Igor, additional, Dähnert, Ingo, additional, Tzifa, Aphrodite, additional, Djordjevic, Stefan A., additional, Ilic, Slobodan, additional, Milovanovic, Vladimir, additional, Bijelic, Maja, additional, Bisenic, Dejan, additional, Kalanj, Jasna, additional, and Djukic, Milan, additional

Published
2023
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26. Aplastic anemia and Turner syndrome

Author

Cuturilo, Goran, primary, Skoric, Dejan, additional, Grkovic, Slobodanka Miletic, additional, Bojic, Vladislav, additional, Rodic, Predrag, additional, and Stefanovic, Igor, additional

Published
2008
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