Search

Your search keyword '"Stephen J. Brough"' showing total 30 results

Search Constraints

Start Over You searched for: Author "Stephen J. Brough" Remove constraint Author: "Stephen J. Brough"
30 results on '"Stephen J. Brough"'

Search Results

1. Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade.

2. Use of Cryopreserved Cells for Enabling Greater Flexibility in Compound Profiling

Catalog

Books, media, physical & digital resources

3. Characterization of SB-705498, a Potent and Selective Vanilloid Receptor-1 (VR1/TRPV1) Antagonist That Inhibits the Capsaicin-, Acid-, and Heat-Mediated Activation of the Receptor

4. Characterisation of the binding of [3 H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor

5. 1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor

6. SB-334867-A: the first selective orexin-1 receptor antagonist

7. Pharmacological characterisation of human 5-HT2 receptor subtypes

8. Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX 1 ) receptors, with downstream 5-HT 2C receptor involvement

9. Discovery of potent and selective peptide agonists at the GRP-preferring bombesin receptor (BB2)

10. Characterisation of an endogenous bombesin receptor in CHO/DG44 cells

11. Characterization using FLIPR of rat vanilloid receptor (rVR1) pharmacology

12. Site-specific splice variation of the human P2X4 receptor

13. Functional effects of the muscarinic receptor agonist, xanomeline, at 5-HT1and 5-HT2receptors

14. Identification of clinical candidates from the benzazepine class of histamine H3 receptor antagonists

15. Novel spirotetracyclic zwitterionic dual H(1)/5-HT(2A) receptor antagonists for the treatment of sleep disorders

16. Suprapubic catheter displacement: a forgotten phenomenon

17. Towards the discovery of New Hypnotic Agents: Synthesis and Preliminary Pharmacological Evaluation of a Novel Class of Dibenzo[a,d]cycloheptene Derivatives

18. The hypocretins are weak agonists at recombinant human orexin-1 and orexin-2 receptors

19. Use of aequorin for G protein-coupled receptor hit identification and compound profiling

20. Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR

21. Discovery of small molecule antagonists of TRPV1

22. Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor

23. Pharmacological characterisation of the orexin receptor subtype mediating postsynaptic excitation in the rat dorsal raphe nucleus

24. Pharmacology of vanilloids at recombinant and endogenous rat vanilloid receptors

25. Comparison of effects of anandamide at recombinant and endogenous rat vanilloid receptors

26. Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1

27. Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology

28. Structure-activity analysis of truncated orexin-A analogues at the orexin-1 receptor

29. Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment

30. Prediction of Thorough QT study results using action potential simulations based on ion channel screens