132 results on '"Steven Hunt"'
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2. Latin and Greek in English Primary Schools – seedlings of a classical education
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Steven Hunt
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Primary Schools ,Latin ,ancient Greek ,languages learning ,Classics ,Key Stage 2 ,Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Abstract
This article describes some of the main features of classical languages and history learning at the primary school level in England at the current time. It briefly examines the context and education policy background and government and teachers' beliefs in the value and status of classical subjects, especially the Latin language as an aid to learning other languages and as a support for developing and improving students' English literacy. There is some overlap with the literature review co-authored by Holmes-Henderson and Kelly for the British government (Holmes-Henderson and Kelly, 2022) and a recent piece by myself about provision of teaching and resources in the Bulletin of the Council of University Classics Departments (Hunt, 2022a). I hope to develop further some of these ideas and draw out some discussions about resources, pedagogy and learning aims for possible future directions of classical languages learning at the primary level.
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- 2024
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3. Editorial
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Published
- 2024
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4. Telling Tales in Nature. Underworld Tales (L.) Robinson Pp. 46. Seattle, USA: Independently published, 2022. Paper, £5.99. ISBN: 979-8791380333.
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Published
- 2024
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5. Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci
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Lisa de las Fuentes, Karen L. Schwander, Michael R. Brown, Amy R. Bentley, Thomas W. Winkler, Yun Ju Sung, Patricia B. Munroe, Clint L. Miller, Hugo Aschard, Stella Aslibekyan, Traci M. Bartz, Lawrence F. Bielak, Jin Fang Chai, Ching-Yu Cheng, Rajkumar Dorajoo, Mary F. Feitosa, Xiuqing Guo, Fernando P. Hartwig, Andrea Horimoto, Ivana Kolčić, Elise Lim, Yongmei Liu, Alisa K. Manning, Jonathan Marten, Solomon K. Musani, Raymond Noordam, Sandosh Padmanabhan, Tuomo Rankinen, Melissa A. Richard, Paul M. Ridker, Albert V. Smith, Dina Vojinovic, Alan B. Zonderman, Maris Alver, Mathilde Boissel, Kaare Christensen, Barry I. Freedman, Chuan Gao, Franco Giulianini, Sarah E. Harris, Meian He, Fang-Chi Hsu, Brigitte Kühnel, Federica Laguzzi, Xiaoyin Li, Leo-Pekka Lyytikäinen, Ilja M. Nolte, Alaitz Poveda, Rainer Rauramaa, Muhammad Riaz, Antonietta Robino, Tamar Sofer, Fumihiko Takeuchi, Bamidele O. Tayo, Peter J. van der Most, Niek Verweij, Erin B. Ware, Stefan Weiss, Wanqing Wen, Lisa R. Yanek, Yiqiang Zhan, Najaf Amin, Dan E. Arking, Christie Ballantyne, Eric Boerwinkle, Jennifer A. Brody, Ulrich Broeckel, Archie Campbell, Mickaël Canouil, Xiaoran Chai, Yii-Der Ida Chen, Xu Chen, Kumaraswamy Naidu Chitrala, Maria Pina Concas, Ulf de Faire, Renée de Mutsert, H. Janaka de Silva, Paul S. de Vries, Ahn Do, Jessica D. Faul, Virginia Fisher, James S. Floyd, Terrence Forrester, Yechiel Friedlander, Giorgia Girotto, C. Charles Gu, Göran Hallmans, Sami Heikkinen, Chew-Kiat Heng, Georg Homuth, Steven Hunt, M. Arfan Ikram, David R. Jacobs, Maryam Kavousi, Chiea Chuen Khor, Tuomas O. Kilpeläinen, Woon-Puay Koh, Pirjo Komulainen, Carl D. Langefeld, Jingjing Liang, Kiang Liu, Jianjun Liu, Kurt Lohman, Reedik Mägi, Ani W. Manichaikul, Colin A. McKenzie, Thomas Meitinger, Yuri Milaneschi, Matthias Nauck, Christopher P. Nelson, Jeffrey R. O’Connell, Nicholette D. Palmer, Alexandre C. Pereira, Thomas Perls, Annette Peters, Ozren Polašek, Olli T. Raitakari, Kenneth Rice, Treva K. Rice, Stephen S. Rich, Charumathi Sabanayagam, Pamela J. Schreiner, Xiao-Ou Shu, Stephen Sidney, Mario Sims, Jennifer A. Smith, John M. Starr, Konstantin Strauch, E. Shyong Tai, Kent D. Taylor, Michael Y. Tsai, André G. Uitterlinden, Diana van Heemst, Melanie Waldenberger, Ya-Xing Wang, Wen-Bin Wei, Gregory Wilson, Deng Xuan, Jie Yao, Caizheng Yu, Jian-Min Yuan, Wei Zhao, Diane M. Becker, Amélie Bonnefond, Donald W. Bowden, Richard S. Cooper, Ian J. Deary, Jasmin Divers, Tõnu Esko, Paul W. Franks, Philippe Froguel, Christian Gieger, Jost B. Jonas, Norihiro Kato, Timo A. Lakka, Karin Leander, Terho Lehtimäki, Patrik K. E. Magnusson, Kari E. North, Ioanna Ntalla, Brenda Penninx, Nilesh J. Samani, Harold Snieder, Beatrice Spedicati, Pim van der Harst, Henry Völzke, Lynne E. Wagenknecht, David R. Weir, Mary K. Wojczynski, Tangchun Wu, Wei Zheng, Xiaofeng Zhu, Claude Bouchard, Daniel I. Chasman, Michele K. Evans, Ervin R. Fox, Vilmundur Gudnason, Caroline Hayward, Bernardo L. Horta, Sharon L. R. Kardia, Jose Eduardo Krieger, Dennis O. Mook-Kanamori, Patricia A. Peyser, Michael M. Province, Bruce M. Psaty, Igor Rudan, Xueling Sim, Blair H. Smith, Rob M. van Dam, Cornelia M. van Duijn, Tien Yin Wong, Donna K. Arnett, Dabeeru C. Rao, James Gauderman, Ching-Ti Liu, Alanna C. Morrison, Jerome I. Rotter, and Myriam Fornage
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educational attainment ,lipids ,cholesterol ,triglycerides ,genome-wide association study ,meta-analysis ,Genetics ,QH426-470 - Abstract
Introduction: Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes.Methods: A two-stage genome-wide meta-analysis of low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride (TG) levels was performed while accounting for gene-educational attainment interactions in up to 226,315 individuals from five population groups. We considered two educational attainment variables: “Some College” (yes/no, for any education beyond high school) and “Graduated College” (yes/no, for completing a 4-year college degree). Genome-wide significant (p < 5 × 10−8) and suggestive (p < 1 × 10−6) variants were identified in Stage 1 (in up to 108,784 individuals) through genome-wide analysis, and those variants were followed up in Stage 2 studies (in up to 117,531 individuals).Results: In combined analysis of Stages 1 and 2, we identified 18 novel lipid loci (nine for LDL, seven for HDL, and two for TG) by two degree-of-freedom (2 DF) joint tests of main and interaction effects. Four loci showed significant interaction with educational attainment. Two loci were significant only in cross-population analyses. Several loci include genes with known or suggested roles in adipose (FOXP1, MBOAT4, SKP2, STIM1, STX4), brain (BRI3, FILIP1, FOXP1, LINC00290, LMTK2, MBOAT4, MYO6, SENP6, SRGAP3, STIM1, TMEM167A, TMEM30A), and liver (BRI3, FOXP1) biology, highlighting the potential importance of brain-adipose-liver communication in the regulation of lipid metabolism. An investigation of the potential druggability of genes in identified loci resulted in five gene targets shown to interact with drugs approved by the Food and Drug Administration, including genes with roles in adipose and brain tissue.Discussion: Genome-wide interaction analysis of educational attainment identified novel lipid loci not previously detected by analyses limited to main genetic effects.
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- 2023
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6. Novellas and Free Voluntary Reading: an overview and some starting points for further research into practice
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Steven Hunt
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Latin ,free voluntary reading ,extensive reading ,pedagogy ,Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Abstract
In the US the use of extensive reading in Latin for school students to develop vocabulary growth and attain reading fluency is an emerging classroom practice. To meet the demand for resources, a small but growing number of teachers have started to make available self-published short Latin stories or ‘novellas’, designed to provide students with extensive reading material in Latin at an age-appropriate level for novice and intermediate level students. There are now over 100 such short books, written in Latin, on a variety of topics, suitable for beginner and intermediate students (typically of between one and two years taught Latin). This article contains three areas of interest: the rationale, challenges and successes of writing and using these resources in the school classroom; a snapshot survey of a range of publications, to give readers a ‘flavour’ of the materials; and some further reading.
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- 2022
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7. Editorial
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Published
- 2022
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8. Editorial
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Published
- 2023
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9. Editorial
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Published
- 2021
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10. Introducing Latin. Non-specialist Latin teachers talk
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Steven Hunt
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Latin ,National Curriculum ,Ofsted ,EBacc ,qualifications ,Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Abstract
This article describes the ways in which four non-specialist Latin teachers are introducing Latin to their schools1. The interviews reported here took place in four secondary schools in London and the South-East in 2019. The interviews were informal and were held with the teachers while I was consultant on behalf of the charity Classics for All while training non-specialists to introduce Latin into their schools, where no classical subjects had been offered previously. Teachers use Latin to meet Ofsted targets for the uptake of the English Baccalaureate (henceforth EBacc2) and to provide a broad and ambitious curriculum for all students. Resources and subject knowledge provide intellectual challenge and also stimulation. In conclusion I recommend greater support from the Department for Education (DfE) working with subject organisations to develop a coherent strategy for introducing classical subjects in state-maintained schools in order to support DfE and Ofsted objectives.
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- 2020
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11. Editorial
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Published
- 2020
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12. Teacher Trainees Telling Tales
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Steven Hunt, Anya Morrice, Daisy Knox, Iaomie Malik, Jordan Hawkesworth, Eleanor Barker, Clare Mahon, Jaspal Ubhi, Giorgio Molteni, Rachel Hambly, Aleksandra Ruczynska, Lawrence McNally, and Benjamin Connor
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Abstract
Trainees were encouraged to tell a mythological story to the class, lasting about ten minutes. They could use props and other visual aids if they wished, but the emphasis was for them to practise speaking before the class, using prompt cards if necessary, and employing all the techniques of a professional oral ‘poet’ – such as gesture, eye contact, tone of voice and so on. There is obviously considerable general interest among younger students about mythology. Locally, interest is captured by the Cambridge School Classics project which puts on an annual Ovid Mythology competition and the website War with Troy is used by several of the schools where trainees are placed. Its use as a stimulus for learning has been well-documented by its author and past PGCE subject lecturer Bob Lister (2005, 2007) and by Walker (2018), a former teacher trainee from the faculty. Some of the Latin textbooks such as Minimus (Bell, 1999) and Suburani (Hands-Up Education, 2020) contain myth episodes and are familiar to the teacher trainees. The GCSE and A Level qualifications often contain mythological subject matter. Khan-Evans (2018) has shown how older students of Classics have retained deep-rooted affection for mythological stories in their earlier schooldays. Research into the power of mythological storytelling as a stimulus for learning, creative arts and even therapy is current, as the Our Mythical Childhood project (2020) has demonstrated. A book of the project's work is eagerly anticipated next year. The recent Troy exhibition at the British Museum has also awoken considerable interest.
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- 2020
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13. Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells
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Ramesh Chittajallu, Kurt Auville, Vivek Mahadevan, Mandy Lai, Steven Hunt, Daniela Calvigioni, Kenneth A Pelkey, Kareem A Zaghloul, and Chris J McBain
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neurogliaform cell ,intrinsic excitablity ,plasticity ,interneuron ,Medicine ,Science ,Biology (General) ,QH301-705.5 - Abstract
The ability to modulate the efficacy of synaptic communication between neurons constitutes an essential property critical for normal brain function. Animal models have proved invaluable in revealing a wealth of diverse cellular mechanisms underlying varied plasticity modes. However, to what extent these processes are mirrored in humans is largely uncharted thus questioning their relevance in human circuit function. In this study, we focus on neurogliaform cells, that possess specialized physiological features enabling them to impart a widespread inhibitory influence on neural activity. We demonstrate that this prominent neuronal subtype, embedded in both mouse and human neural circuits, undergo remarkably similar activity-dependent modulation manifesting as epochs of enhanced intrinsic excitability. In principle, these evolutionary conserved plasticity routes likely tune the extent of neurogliaform cell mediated inhibition thus constituting canonical circuit mechanisms underlying human cognitive processing and behavior.
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- 2020
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14. Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons
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Kenneth A Pelkey, Daniela Calvigioni, Calvin Fang, Geoffrey Vargish, Tyler Ekins, Kurt Auville, Jason C Wester, Mandy Lai, Connie Mackenzie-Gray Scott, Xiaoqing Yuan, Steven Hunt, Daniel Abebe, Qing Xu, Jordane Dimidschstein, Gordon Fishell, Ramesh Chittajallu, and Chris J McBain
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corelease ,interneuron ,gaba ,glutamate ,vglut3 ,cck ,Medicine ,Science ,Biology (General) ,QH301-705.5 - Abstract
In violation of Dale’s principle several neuronal subtypes utilize more than one classical neurotransmitter. Molecular identification of vesicular glutamate transporter three and cholecystokinin expressing cortical interneurons (CCK+VGluT3+INTs) has prompted speculation of GABA/glutamate corelease from these cells for almost two decades despite a lack of direct evidence. We unequivocally demonstrate CCK+VGluT3+INT-mediated GABA/glutamate cotransmission onto principal cells in adult mice using paired recording and optogenetic approaches. Although under normal conditions, GABAergic inhibition dominates CCK+VGluT3+INT signaling, glutamatergic signaling becomes predominant when glutamate decarboxylase (GAD) function is compromised. CCK+VGluT3+INTs exhibit surprising anatomical diversity comprising subsets of all known dendrite targeting CCK+ interneurons in addition to the expected basket cells, and their extensive circuit innervation profoundly dampens circuit excitability under normal conditions. However, in contexts where the glutamatergic phenotype of CCK+VGluT3+INTs is amplified, they promote paradoxical network hyperexcitability which may be relevant to disorders involving GAD dysfunction such as schizophrenia or vitamin B6 deficiency.
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- 2020
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15. The Virtue of Variety: Opening the Doors to Wider Pedagogical Practices in UK Schools and Universities
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Steven Hunt, Clive Letchford, Mair Lloyd, Laura Manning, and Rachel Plummer
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Abstract
The Council of University Classics Departments surveys of 1995 (CUCD, 1995) and 2012 (CUCD, 2012) demonstrated a restricted set of approaches to Latin teaching in UK universities with little evidence of activity outside grammar-translation and graded reading. Despite this, in the 2012 survey, some United Kingdom university tutors made claims for the benefits of experiencing more varied pedagogy, including communicative Latin, in their own previous study and in Summer School Immersion events (Lloyd, 2016a). In schools, a number of challenges continue to provide motivation to move away from current norms of provision (Forrest, 1996; Lister, 2007; Hunt, 2016). Meanwhile, in America, changes in curriculum and methods are being proposed and implemented to meet the challenges of falling enrolment on Latin and other Classics courses.
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- 2018
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16. Getting Classics into Secondary Schools: Three Case Studies
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Abstract
Despite the challenges which are involved, some secondary schools show determination to get Classics onto the timetable and into their curricular provision. The following three case studies draw on interviews with the people directly involved in doing so: the Principals and the teachers themselves. These experiences were captured at the time when they were getting Classics into their schools. The first is derived from an interview with a qualified specialist Classics teacher, ‘Rachel’, working in London. Latin already had a presence there from when the school had employed a part-time teacher; the remit was the development of a full Classics department. The second is based on interviews with the school head teacher and a non-specialist Modern Languages teacher ‘Yvonne’ who had been employed to start a Classics department from scratch in a school in the Midlands. The third is based on an interview with the Principal of an academy which had decided to introduce Latin not only into her own school with a new teacher ‘George’, but also into one that was not yet built. The respondents’ real names have, of course, been changed.
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- 2018
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17. Editorial
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Published
- 2019
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18. Neto Auxiliary Subunits Regulate Interneuron Somatodendritic and Presynaptic Kainate Receptors to Control Network Inhibition
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Megan S. Wyeth, Kenneth A. Pelkey, Xiaoqing Yuan, Geoffrey Vargish, April D. Johnston, Steven Hunt, Calvin Fang, Daniel Abebe, Vivek Mahadevan, André Fisahn, Michael W. Salter, Roderick R. McInnes, Ramesh Chittajallu, and Chris J. McBain
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interneuron ,kainite ,hippocampus ,parvalbumin ,cholecystokinin ,somatostatin ,neto1 ,neto2 ,Biology (General) ,QH301-705.5 - Abstract
Although Netos are considered auxiliary subunits critical for kainate receptor (KAR) function, direct evidence for their regulation of native KARs is limited. Because Neto KAR regulation is GluK subunit/Neto isoform specific, such regulation must be determined in cell-type-specific contexts. We demonstrate Neto1/2 expression in somatostatin (SOM)-, cholecystokinin/cannabinoid receptor 1 (CCK/CB1)-, and parvalbumin (PV)-containing interneurons. KAR-mediated excitation of these interneurons is contingent upon Neto1 because kainate yields comparable effects in Neto2 knockouts and wild-types but fails to excite interneurons or recruit inhibition in Neto1 knockouts. In contrast, presynaptic KARs in CCK/CB1 interneurons are dually regulated by both Neto1 and Neto2. Neto association promotes tonic presynaptic KAR activation, dampening CCK/CB1 interneuron output, and loss of this brake in Neto mutants profoundly increases CCK/CB1 interneuron-mediated inhibition. Our results confirm that Neto1 regulates endogenous somatodendritic KARs in diverse interneurons and demonstrate Neto regulation of presynaptic KARs in mature inhibitory presynaptic terminals.
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- 2017
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19. Beyond the Nile. Egypt and the Classical World J. Spier, T. Potts, and S. Cole (Eds). Los Angeles, Getty Museums. ISBN 978-1606065518. Pp. 360. Ill. 200. Hardback. £45.00.
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Published
- 2020
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20. Teaching Sensitive Topics in the Secondary Classics Classroom
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Abstract
This article examines how a number of teachers of Classics at secondary school level say they deal with sensitive topics, such as violence, religious belief, death and sex and sexuality. In the secondary school original texts are read partly for improving the students' understanding of the language and partly for the study of other aspects of the ancient society, such as the subject matter and the process of a legal case, for example. Therefore, sensitive topics often arise incidentally during the reading of a text rather than because they are the particular feature of the reading. Should teachers brush past such an topic for fear of causing offence or getting into trouble with school authorities or parents, or should they use the topic to develop their students' understanding of the topic at hand – and if the latter, how far should they go?
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- 2016
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21. Teaching Roman Food at Key Stage 3: Building Knowledge Through an Enquiry Question
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Abstract
Apromenade lesson is when the learners get up and source, identify and evaluate information from materials attached to the walls of the classroom or a corridor or some other space in the school. The students have to walk around the ‘exhibits’ to find out something and note it down as they go. This activity can forms a part of a sequence of tasks in a lesson. It works well for any subject matter which is highly visual, such as images taken from Pompeian wall-paintings, for example, or even for enlarged text selections.
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- 2015
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22. Starting to Teach Latin
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Steven Hunt
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- 2023
23. Teaching Latin: Contexts, Theories, Practices
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Steven Hunt
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- 2022
24. Adaptive teaching: Latin and the use of digital parsing tools
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Rebecca Coe, Emma Cope, and Steven Hunt
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adaptive teaching ,digital parsing tools ,blended language approach ,Cambridge Latin Course ,Suburani ,Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Abstract
The Initial Teacher Training (ITT) Common Core Framework (CCF) requires all teachers to adapt classroom teaching to support all students (Department for Education, 2024). While the Department for Education's previously-encouraged concept of ‘differentiation’ was well-intentioned, in that tasks were meant to be graded to support and develop all students' learning in a class where there were many different levels of prior attainment, it tended to mean that in practice in the classroom different tasks were often set to cater to the supposed different learning attributes of students. Differentiation has now been superseded by the concept of ‘adaptive teaching’. Adaptive teaching is characterised by teaching that takes account of the range in prior attainment of students and anticipates barriers to learning by providing resources or specific support so that they may all achieve the same intended outcomes. Classics teaching is often characterised by the reading of large amounts of text, both in the original languages of Latin or ancient Greek or in translation. Students in the Classics classroom contain a wide range of prior attainment, cultural experiences and may have barriers to learning, such as Special Educational Needs and Disabilities. This article presents findings of how the use of a blended language approach, involving the digital parsing tools in the Cambridge Latin Course and Suburani Latin course books, improved the quantity of translation of Latin achieved by students of mixed prior attainment and encouraged a more effective use of classroom time to develop deeper comprehension and understanding of the translated texts.
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25. Classical Studies Trends: teaching Classics in secondary schools in the UK
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Steven Hunt
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Latin ,Greek ,Classics ,National Survey ,Classics education ,Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Abstract
The Classical Association, working with the charity Classics for All, is conscious of the vulnerability of Classics in the secondary education system and wants to understand the reasons behind this. Concern about the decline of classical subjects at GCSE and A Level has been mounting, indicated largely by exam entry data suggesting that entries for classical subjects are low and in the case of the ancient languages in decline.1 The Council of University Classics Departments Bulletin annually publishes statistics for student entries for national examinations at GCSE and A level in classical subjects. But this does not capture the full picture, nor does it represent the other constituent parts of the UK, which have their own examination systems. Therefore, in late 2021 the Classical Association and Classics for All designed a new Classical Studies Survey (the ‘Survey’), to fill in more detailed information about what is going on in schools' classics departments more widely through the UK, across Key Stages 3–5, and to provide practising teachers with an opportunity to make recommendations for future developments in courses for classical subjects. The Survey asked teachers to comment on the current situation for Latin, Ancient Greek, Classical Civilisation and Ancient History, the factors affecting these trends, and what support they considered they would need for Classics to survive in their institutions. This Survey collated data rigorously and enables the Classical Association on behalf of the classics teaching community to make compelling arguments in relation to education policies and examination reform.
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26. Editorial
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Full Text
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27. Quot capita nunc? (A.) Belzer-Carroll and (R.) Pejic Pp. 47. Independently published, 2023. Paper, £11.57. ISBN-13: 979-8667885894
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Full Text
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28. Telling Tales in Nature. Forest Tales (L.) Robinson Pp. 56. Independently published, 2022. Paper, £6.00. ISBN: 979-8367880434.
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Steven Hunt
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Theory and practice of education ,LB5-3640 ,Ancient history ,D51-90 ,Greek language and literature. Latin language and literature ,PA - Full Text
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29. Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy
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Julio Garcia-Aguilar, Sujata Patil, Marc J. Gollub, Jin K. Kim, Jonathan B. Yuval, Hannah M. Thompson, Floris S. Verheij, Dana M. Omer, Meghan Lee, Richard F. Dunne, Jorge Marcet, Peter Cataldo, Blase Polite, Daniel O. Herzig, David Liska, Samuel Oommen, Charles M. Friel, Charles Ternent, Andrew L. Coveler, Steven Hunt, Anita Gregory, Madhulika G. Varma, Brian L. Bello, Joseph C. Carmichael, John Krauss, Ana Gleisner, Philip B. Paty, Martin R. Weiser, Garrett M. Nash, Emmanouil Pappou, José G. Guillem, Larissa Temple, Iris H. Wei, Maria Widmar, Sabrina Lin, Neil H. Segal, Andrea Cercek, Rona Yaeger, J. Joshua Smith, Karyn A. Goodman, Abraham J. Wu, and Leonard B. Saltz
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Cancer Research ,Rectal Neoplasms ,Chemoradiotherapy ,Organ Preservation ,Adenocarcinoma ,Disease-Free Survival ,Neoadjuvant Therapy ,Oxaliplatin ,Oncology ,Antineoplastic Combined Chemotherapy Protocols ,Humans ,Fluorouracil ,Prospective Studies ,Capecitabine ,Neoplasm Staging - Abstract
PURPOSE Prospective data on the efficacy of a watch-and-wait strategy to achieve organ preservation in patients with locally advanced rectal cancer treated with total neoadjuvant therapy are limited. METHODS In this prospective, randomized phase II trial, we assessed the outcomes of 324 patients with stage II or III rectal adenocarcinoma treated with induction chemotherapy followed by chemoradiotherapy (INCT-CRT) or chemoradiotherapy followed by consolidation chemotherapy (CRT-CNCT) and either total mesorectal excision (TME) or watch-and-wait on the basis of tumor response. Patients in both groups received 4 months of infusional fluorouracil-leucovorin-oxaliplatin or capecitabine-oxaliplatin and 5,000 to 5,600 cGy of radiation combined with either continuous infusion fluorouracil or capecitabine during radiotherapy. The trial was designed as two stand-alone studies with disease-free survival (DFS) as the primary end point for both groups, with a comparison to a null hypothesis on the basis of historical data. The secondary end point was TME-free survival. RESULTS Median follow-up was 3 years. Three-year DFS was 76% (95% CI, 69 to 84) for the INCT-CRT group and 76% (95% CI, 69 to 83) for the CRT-CNCT group, in line with the 3-year DFS rate (75%) observed historically. Three-year TME-free survival was 41% (95% CI, 33 to 50) in the INCT-CRT group and 53% (95% CI, 45 to 62) in the CRT-CNCT group. No differences were found between groups in local recurrence-free survival, distant metastasis-free survival, or overall survival. Patients who underwent TME after restaging and patients who underwent TME after regrowth had similar DFS rates. CONCLUSION Organ preservation is achievable in half of the patients with rectal cancer treated with total neoadjuvant therapy, without an apparent detriment in survival, compared with historical controls treated with chemoradiotherapy, TME, and postoperative chemotherapy.
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- 2022
30. Deep learning based on co-registered ultrasound and photoacoustic imaging improves the assessment of rectal cancer treatment response
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Yixiao Lin, Sitai Kou, Haolin Nie, Hongbo Luo, Ahmed Eltahir, Will Chapman, Steven Hunt, Matthew Mutch, and Quing Zhu
- Subjects
Atomic and Molecular Physics, and Optics ,Article ,Biotechnology - Abstract
Identifying complete response (CR) after rectal cancer preoperative treatment is critical to deciding subsequent management. Imaging techniques, including endorectal ultrasound and MRI, have been investigated but have low negative predictive values. By imaging post-treatment vascular normalization using photoacoustic microscopy, we hypothesize that co-registered ultrasound and photoacoustic imaging will better identify complete responders. In this study, we used in vivo data from 21 patients to develop a robust deep learning model (US-PAM DenseNet) based on co-registered dual-modality ultrasound (US) and photoacoustic microscopy (PAM) images and individualized normal reference images. We tested the model’s accuracy in differentiating malignant from non-cancer tissue. Compared to models based on US alone (classification accuracy 82.9 ± 1.3%, AUC 0.917(95%CI: 0.897-0.937)), the addition of PAM and normal reference images improved the model performance significantly (accuracy 92.4 ± 0.6%, AUC 0.968(95%CI: 0.960-0.976)) without increasing model complexity. Additionally, while US models could not reliably differentiate images of cancer from those of normalized tissue with complete treatment response, US-PAM DenseNet made accurate predictions from these images. For use in the clinical settings, US-PAM DenseNet was extended to classify entire US-PAM B-scans through sequential ROI classification. Finally, to help focus surgical evaluation in real time, we computed attention heat maps from the model predictions to highlight suspicious cancer regions. We conclude that US-PAM DenseNet could improve the clinical care of rectal cancer patients by identifying complete responders with higher accuracy than current imaging techniques.
- Published
- 2023
31. Of Mice and Men: Evolutionary Conservation of Detonator Synapse Properties
- Author
-
Kenneth A. Pelkey, Geoffrey Vargish, Leonardo Pellegrini, Daniela Calvigioni, Julio Chapeton, Xiaoqing Yuan, Steven Hunt, Alexander Cummins, Mark Eldridge, James Pickel, Ramesh Chittajallu, Bruno Averbeck, Katalin Toth, Kareem Zaghloul, Chris McBain, and Sneak Peek Administrator
- Published
- 2023
32. Starting to Teach Latin (Second Edition)
- Author
-
Steven Hunt
- Published
- 2023
33. Starting to Teach Latin
- Author
-
Steven Hunt
- Published
- 2016
34. Rectal Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology
- Author
-
Al B. Benson, Alan P. Venook, Mahmoud M. Al-Hawary, Nilofer Azad, Yi-Jen Chen, Kristen K. Ciombor, Stacey Cohen, Harry S. Cooper, Dustin Deming, Ignacio Garrido-Laguna, Jean L. Grem, Andrew Gunn, J. Randolph Hecht, Sarah Hoffe, Joleen Hubbard, Steven Hunt, William Jeck, Kimberly L. Johung, Natalie Kirilcuk, Smitha Krishnamurthi, Jennifer K. Maratt, Wells A. Messersmith, Jeffrey Meyerhardt, Eric D. Miller, Mary F. Mulcahy, Steven Nurkin, Michael J. Overman, Aparna Parikh, Hitendra Patel, Katrina Pedersen, Leonard Saltz, Charles Schneider, David Shibata, John M. Skibber, Constantinos T. Sofocleous, Eden Stotsky-Himelfarb, Anna Tavakkoli, Christopher G. Willett, Kristina Gregory, and Lisa Gurski
- Subjects
Oncology ,Rectal Neoplasms ,Humans ,Medical Oncology ,Neoadjuvant Therapy - Abstract
This selection from the NCCN Guidelines for Rectal Cancer focuses on management of malignant polyps and resectable nonmetastatic rectal cancer because important updates have been made to these guidelines. These recent updates include redrawing the algorithms for stage II and III disease to reflect new data supporting the increasingly prominent role of total neoadjuvant therapy, expanded recommendations for short-course radiation therapy techniques, and new recommendations for a “watch-and-wait” nonoperative management technique for patients with cancer that shows a complete response to neoadjuvant therapy. The complete version of the NCCN Guidelines for Rectal Cancer, available online at NCCN.org, covers additional topics including risk assessment, pathology and staging, management of metastatic disease, posttreatment surveillance, treatment of recurrent disease, and survivorship.
- Published
- 2022
35. Intrinsic electrophysiological properties predict variability in morphology and connectivity among striatal Parvalbumin-expressing Pthlh-cells
- Author
-
Jens Hjerling-Leffler, Carolina Bengtsson Gonzales, Chris J. McBain, Ana B. Muñoz-Manchado, and Steven Hunt
- Subjects
0301 basic medicine ,Nervous system ,Male ,Cell type ,Population ,Electrophysiological Phenomena ,lcsh:Medicine ,Striatum ,Article ,03 medical and health sciences ,Mice ,0302 clinical medicine ,Thalamus ,Interneurons ,medicine ,Animals ,education ,lcsh:Science ,Regulation of gene expression ,education.field_of_study ,Multidisciplinary ,biology ,lcsh:R ,Motor Cortex ,Dendrites ,Axons ,Corpus Striatum ,Cellular neuroscience ,Electrophysiology ,030104 developmental biology ,medicine.anatomical_structure ,Parvalbumins ,Gene Expression Regulation ,nervous system ,biology.protein ,Neuronal physiology ,Basal ganglia ,Female ,lcsh:Q ,Neuroscience ,030217 neurology & neurosurgery ,Parvalbumin - Abstract
Determining the cellular content of the nervous system in terms of cell types and the rules of their connectivity represents a fundamental challenge to the neurosciences. The recent advent of high-throughput techniques, such as single-cell RNA-sequencing has allowed for greater resolution in the identification of cell types and/or states. Although most of the current neuronal classification schemes comprise discrete clusters, several recent studies have suggested that, perhaps especially, within the striatum, neuronal populations exist in continua, with regards to both their molecular and electrophysiological properties. Whether these continua are stable properties, established during development, or if they reflect acute differences in activity-dependent regulation of critical genes is currently unknown. We set out to determine whether gradient-like molecular differences in the recently described Pthlh-expressing inhibitory interneuron population, which contains the Pvalb-expressing cells, correlate with differences in morphological and connectivity properties. We show that morphology and long-range inputs correlate with a spatially organized molecular and electrophysiological gradient of Pthlh-interneurons, suggesting that the processing of different types of information (by distinct anatomical striatal regions) has different computational requirements.
- Published
- 2020
36. Teacher Trainees Telling Tales
- Author
-
Iaomie Malik, Eleanor Barker, Lawrence McNally, Jordan Hawkesworth, Rachel Hambly, Anya Morrice, Benjamin Connor, Daisy Knox, Steven Hunt, Jaspal Ubhi, Giorgio Molteni, Clare Mahon, and Aleksandra Ruczynska
- Subjects
History ,media_common.quotation_subject ,05 social sciences ,Subject (philosophy) ,050301 education ,Mythology ,The arts ,Education ,Visual arts ,Exhibition ,Power (social and political) ,03 medical and health sciences ,0302 clinical medicine ,030220 oncology & carcinogenesis ,Affection ,Classics ,Cambridge School ,0503 education ,Storytelling ,media_common - Abstract
Trainees were encouraged to tell a mythological story to the class, lasting about ten minutes. They could use props and other visual aids if they wished, but the emphasis was for them to practise speaking before the class, using prompt cards if necessary, and employing all the techniques of a professional oral ‘poet’ – such as gesture, eye contact, tone of voice and so on. There is obviously considerable general interest among younger students about mythology. Locally, interest is captured by the Cambridge School Classics project which puts on an annual Ovid Mythology competition and the website War with Troy is used by several of the schools where trainees are placed. Its use as a stimulus for learning has been well-documented by its author and past PGCE subject lecturer Bob Lister (2005, 2007) and by Walker (2018), a former teacher trainee from the faculty. Some of the Latin textbooks such as Minimus (Bell, 1999) and Suburani (Hands-Up Education, 2020) contain myth episodes and are familiar to the teacher trainees. The GCSE and A Level qualifications often contain mythological subject matter. Khan-Evans (2018) has shown how older students of Classics have retained deep-rooted affection for mythological stories in their earlier schooldays. Research into the power of mythological storytelling as a stimulus for learning, creative arts and even therapy is current, as the Our Mythical Childhood project (2020) has demonstrated. A book of the project's work is eagerly anticipated next year. The recent Troy exhibition at the British Museum has also awoken considerable interest.
- Published
- 2020
37. Adaptive teaching for GCSE and A level classical literature
- Author
-
Coe, Becky, primary and Steven, Hunt, additional
- Published
- 2022
- Full Text
- View/download PDF
38. Teaching Classics Worldwide : Successes, Challenges and Developments
- Author
-
Steven Hunt, John Bulwer, Steven Hunt, and John Bulwer
- Subjects
- Essays, Classical philology--Study and teaching, Classical literature--Study and teaching, Civilization, Classical--Study and teaching
- Abstract
Designed for instructors in schools and universities, as well as stakeholders and policy-makers in education everywhere, this book is a systematic guide to contemporary school teaching of classical languages, literature and civilisation in major countries across the world. This book examines the trends and assesses the rationale for such diversity in programmes of study and asks the question: What are classical subjects for in today's schools?Each chapter is arranged by geographical area and draws on the experiences of teachers and other education experts in each country, commenting on contemporary practices. Themes such as the impact of national education policies, enrolment, assessment, accessibility and inclusion are discussed. The teaching of Classics has wide variations in practices and purposes from one education system to another: in some, the teaching of Classics continues to be focused on the mastery of language and grammar; in others, active use of the ancient languages is growing in popularity; and yet in others, the focus is shifting towards the study of the languages and civilisations in translation. Presenting an overview survey and comparison of practices across the world, this book is essential reading for instructors and teaching training courses in the world of classical education.
- Published
- 2025
39. Association of prenatal substance use disorders with pregnancy and birth outcomes following bariatric surgery
- Author
-
Jaewhan, Kim, Lance, Davidson, Steven, Hunt, Nathan, Richards, and Ted, Adams
- Subjects
Adult ,Cohort Studies ,Pregnancy Complications ,Pregnancy ,Substance-Related Disorders ,Utah ,Infant, Newborn ,Pregnancy Outcome ,Bariatric Surgery ,Humans ,Female ,Prenatal Care ,Retrospective Studies - Abstract
While an increased risk for substance use disorders (SUD) and also for several adverse pregnancy and birth outcomes in patients who have undergone bariatric surgery have been well documented when considered separately, an association between these important risk factors has not been investigated. This study explored the potential dependence of these two bariatric surgery-related risks.This study was a retrospective cohort study with adult women (18-45) who underwent bariatric surgery between 1996 and 2016 and who gave birth after surgery between 1996 and 2018. The study population consisted of 1849 post-bariatric surgery women with 3010 reported post-surgical births. Subjects with post-surgical, prenatal SUD were identified based on diagnosis codes extracted within the 10 months prior to delivery. Using random-effects logistic regression with retrospective cohort data, preterm birth, low birth weight, macrosomia, Caesarian delivery, congenital anomalies, and neonatal intensive care unit admission were considered as outcomes.About 10% (n = 289) of women had an SUD diagnosis within 10 months prior to child delivery. Women with SUD during pregnancy had significantly more pregnancy and birth complications compared to women without SUD: preterm birth (OR = 2.08, p = 0.03, 95% CI: 1.07-4.03), low birth weight (OR = 3.41, p 0.01, 95% CI: 1.99-5.84), Caesarian delivery (OR = 9.71, p 0.01, 95% CI: 2.69-35.05), and neonatal intensive care unit admission (OR = 3.87, p 0.01, 95% CI: 2.04-7.34). Women with SUD had lower risk for macrosomia than women without SUD (OR = 0.07, p = 0.02, 95% CI: 0.01-0.70).Results from this study demonstrated that post-bariatric surgery women who had SUD during pregnancy had significantly more pregnancy- and birth-related complications than post-surgery pregnant women without SUD, despite the reduction in macrosomia. Where possible, greater prenatal surveillance of post-surgery women with SUD should be considered.
- Published
- 2021
40. America's Urban History
- Author
-
Boehm, Lisa Krissoff, primary and Corey, Steven Hunt, additional
- Published
- 2014
- Full Text
- View/download PDF
41. Active Latin Teaching for The Inclusive Classroom
- Author
-
Steven Hunt
- Subjects
Pedagogy ,Psychology - Published
- 2021
42. Introduction
- Author
-
Mair E. Lloyd and Steven Hunt
- Published
- 2021
43. Reply
- Author
-
William C. Chapman, Parag Parikh, and Steven Hunt
- Subjects
Gastroenterology ,General Medicine - Published
- 2022
44. NCCN Guidelines Insights: Rectal Cancer, Version 6.2020
- Author
-
Al B, Benson, Alan P, Venook, Mahmoud M, Al-Hawary, Mustafa A, Arain, Yi-Jen, Chen, Kristen K, Ciombor, Stacey, Cohen, Harry S, Cooper, Dustin, Deming, Ignacio, Garrido-Laguna, Jean L, Grem, Andrew, Gunn, Sarah, Hoffe, Joleen, Hubbard, Steven, Hunt, Natalie, Kirilcuk, Smitha, Krishnamurthi, Wells A, Messersmith, Jeffrey, Meyerhardt, Eric D, Miller, Mary F, Mulcahy, Steven, Nurkin, Michael J, Overman, Aparna, Parikh, Hitendra, Patel, Katrina, Pedersen, Leonard, Saltz, Charles, Schneider, David, Shibata, John M, Skibber, Constantinos T, Sofocleous, Elena M, Stoffel, Eden, Stotsky-Himelfarb, Christopher G, Willett, Alyse, Johnson-Chilla, and Lisa A, Gurski
- Subjects
Rectal Neoplasms ,Colonic Neoplasms ,Practice Guidelines as Topic ,Humans ,Neoadjuvant Therapy - Abstract
The NCCN Guidelines for Rectal Cancer provide recommendations for the diagnosis, evaluation, treatment, and follow-up of patients with rectal cancer. These NCCN Guidelines Insights summarize the panel discussion behind recent important updates to the guidelines. These updates include clarifying the definition of rectum and differentiating the rectum from the sigmoid colon; the total neoadjuvant therapy approach for localized rectal cancer; and biomarker-targeted therapy for metastatic colorectal cancer, with a focus on new treatment options for patients with BRAF V600E- or HER2 amplification-positive disease.
- Published
- 2020
45. Author response: Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells
- Author
-
Kareem A. Zaghloul, Kenneth A. Pelkey, Daniela Calvigioni, Steven Hunt, Mandy Lai, Ramesh Chittajallu, Chris J. McBain, Vivek Mahadevan, and Kurt Auville
- Subjects
Chemistry ,Neuroscience - Published
- 2020
46. Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells
- Author
-
Chris J. McBain, Steven Hunt, Mandy Lai, Kurt Auville, Daniela Calvigioni, Ramesh Chittajallu, Kareem A. Zaghloul, Vivek Mahadevan, and Kenneth A. Pelkey
- Subjects
Adult ,Male ,Interneuron ,Mouse ,QH301-705.5 ,Science ,interneuron ,Biology ,Inhibitory postsynaptic potential ,neurogliaform cell ,General Biochemistry, Genetics and Molecular Biology ,Glutamatergic ,Neural activity ,Mice ,Young Adult ,Interneurons ,Biological neural network ,medicine ,Animals ,Humans ,Biology (General) ,Brain function ,intrinsic excitablity ,Aged ,Neuronal Plasticity ,General Immunology and Microbiology ,General Neuroscience ,Pyramidal Cells ,Brain ,Depolarization ,General Medicine ,Middle Aged ,Biological Evolution ,Cell mediated immunity ,medicine.anatomical_structure ,plasticity ,Excitatory postsynaptic potential ,GABAergic ,Medicine ,Female ,Neuroscience ,Neuroglia ,Function (biology) ,Research Article ,Human - Abstract
Spatiotemporal interactions between glutamatergic excitatory and GABAergic inhibitory neurons underly input-output transformations critical for complex brain functions. However, the extent of malleability in this interplay particularly that occuring via modifications in GABAergic interneuron recruitment and output is relatively unexplored in humans. We demonstrate that a specialized interneuron subtype collectively termed neurogliaform cells embedded in both mouse and human neural circuits are susceptible to remarkably similar activity-dependent modulation in their intrinsic properties including the previously characterized distal axonal phenomenon known as barrage firing. Interestingly, we reveal a parallel yet hitherto undescribed plasticity, occurring in the absence of barrage firing manifesting as an enhanced efficacy of excitatory depolarizing inputs to somatodendritic domains in eliciting action potential output. In principle, these evolutionary conserved plasticity routes tune the extent of inhibition mediated by neurogliaform cells constituting circuit mechanisms relevant for human cognitive processing and behavior.
- Published
- 2020
47. Author response: Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons
- Author
-
Kurt Auville, Daniel Abebe, Gordon Fishell, Calvin Fang, Daniela Calvigioni, Jason C. Wester, Chris J. McBain, Xiaoqing Yuan, Jordane Dimidschstein, Mandy Lai, Qing Xu, Connie Mackenzie Gray Scott, Steven Hunt, Kenneth A. Pelkey, Ramesh Chittajallu, Tyler Ekins, and Geoffrey A. Vargish
- Subjects
Chemistry ,Glutamate receptor ,GABAergic ,Neuroscience ,Excitation - Published
- 2020
48. Information-seeking behavior and information providers in a K’iche’ Maya community
- Author
-
Robin Shoaps and Steven Hunt
- Subjects
060201 languages & linguistics ,Latin Americans ,business.industry ,05 social sciences ,Developing country ,06 humanities and the arts ,Library and Information Sciences ,Public relations ,Information providers ,Information and Communications Technology ,Information seeking behavior ,0602 languages and literature ,Ethnography ,Maya ,Sociology ,0509 other social sciences ,050904 information & library sciences ,business ,Information provision - Abstract
The study investigated the information-seeking behavior and information provision practices among bilingual (Spanish and K’iche’) students and adults in a Maya town in highland Guatemala. The research combined participant observation ethnography (spanning a total of fifteen months from 2008-17) and interviews with current and retired teachers, Internet café founders and employees, the municipal librarian, students aged 10 and up as well as recent graduates and professionals. Ethnographic insights guided the identification of ‘information,’ the selection of study participants and the nature of questions they were asked. Although a rudimentary library in one form or another has been present since the early 1980s, employees of the library are not, and have never been the primary information providers in Nahualá. Rather, in the past teachers have played that role and many locally important and respected men continue to do so, while currently the employees of one Internet café in particular serve many of the functions characteristically served by librarians in the developed world.
- Published
- 2018
49. Getting Classics Into Schools? Classics and the Social Justice Agenda of the UK Coalition Government, 2010–2015
- Author
-
Steven Hunt
- Subjects
Coalition government ,Political science ,Public administration ,Social justice - Published
- 2018
50. Latin Is Not Dead: The Rise of Communicative Approaches to the Teaching of Latin in the United States
- Author
-
Steven Hunt
- Subjects
Political science - Published
- 2018
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