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This systematic review synthesises the existing research evidence regarding the experiences of young people reintegrated to a mainstream secondary school (MSS) through alternative provision (AP), following permanent exclusion. Eight studies, including one international study, were critically appraised and synthesised following PRISMA guidelines. Three global themes were identified: outcomes of reintegration; factors that support reintegration (facilitators); factors that limit reintegration success (barriers). Findings were configured into a chronological reintegration journey model that outlines the facilitating and limiting factors at three specific stages of the reintegration process: AP support; reintegration planning; reintegration and MSS support. Bringing together multiple stakeholder perspectives from a variety of data sources, this model can serve as a framework for practitioners involved within the reintegration process. This review evidences variability in the methodological quality of the reintegration research evidence and outlines recommendations for future research.

Rhabdomyosarcoma is the commonest soft tissue sarcoma in children. Around one‐third of children with rhabdomyosarcoma experience relapse or have refractory disease, which is associated with a poor prognosis. This systematic review of early phase studies in pediatric relapsed/refractory rhabdomyosarcoma was conducted to inform future research and provide accurate information to families and clinicians making difficult treatment choices. Nine databases and five trial registries were searched in June 2021. Early phase studies of interventions for disease control in patients under 18 years old with relapsed/refractory rhabdomyosarcoma were eligible. No language/geographic restrictions were applied. Studies conducted after 2000 were included. Survival outcomes, response rates, quality of life and adverse event data were extracted. Screening, data extraction and quality assessment (Downs and Black Checklist) were conducted by two researchers. Owing to heterogeneity in the included studies, narrative synthesis was conducted. Of 16,965 records screened, 129 published studies including over 1100 relapsed/refractory rhabdomyosarcoma patients were eligible. Most studies evaluated systemic therapies. Where reported, 70% of studies reported a median progression‐free survival ≤6 months. Objective response rate was 21.6%. Adverse events were mostly hematological. One‐hundred and seven trial registry records of 99 studies were also eligible, 63 of which report they are currently recruiting. Study quality was limited by poor and inconsistent reporting. Outcomes for children with relapsed/refractory rhabdomyosarcoma who enroll on early phase studies are poor. Improving reporting quality and consistency would facilitate the synthesis of early phase studies in relapsed/refractory rhabdomyosarcoma (PROSPERO registration: CRD42021266254). [ABSTRACT FROM AUTHOR]

Robert Buckeye. Left . Amandla Publishing, 2009.95 pp. Paper: $15.00. Left is not a novel that relies on a complex plot structure to engage the reader. On the contrary, Robert [...]

Helen Humphreys. The Frozen Thames . Delacorte Press, 2009. 192 pp. Cloth: $22.00. The River Thames has only frozen over forty times in recorded history. Helen Humphreys's The Frozen Thames [...]