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Your search keyword '"Stobberingh, E E"' showing total 413 results
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413 results on '"Stobberingh, E E"'

4. Nitrofurantoin for the treatment of uncomplicated urinary tract infection in female patients:the impact of dosing regimen, age, and renal function on drug exposure

Author

van Driel, A. A., Muller, A. E., Wijma, R. A., Stobberingh, E. E., Verbon, A., Koch, B. C.P., van Driel, A. A., Muller, A. E., Wijma, R. A., Stobberingh, E. E., Verbon, A., and Koch, B. C.P.

Abstract

Purpose: The aim of this study is to determine nitrofurantoin exposure in female patients with different age and renal function with complaints of an uncomplicated UTI. Also the nitrofurantoin exposure in relation to the dosage regimen will be studied. Methods: Eight general practitioners (GP) participated in the study and included 38 patients with symptoms of an uncomplicated UTI, treated either with a dose of 50 mg q6h or 100 mg q12h, upon the discretion of the GP. Nitrofurantoin exposure was quantified in the patient’s 24-h urine samples by UHPLC-UV and the area under the curve was calculated. Results: The 38 patients provided a range of 2–17 urine samples. The urine nitrofurantoin exposure was 1028 mg h/L for the patients receiving 50 mg q6h and 1036 mg h/L for those treated with 100 mg q12h (p = 0.97) and was not affected by age and eGFR (p = 0.64 and p = 0.34, respectively). Conclusion: The data obtained do not support the discouragement of nitrofurantoin use in the elderly and in patients with impaired renal function. Since only a small number of patients were included, a larger study with more patients is warranted to evaluate nitrofurantoin exposure and adverse effects.

Published
2023

7. Additional file 1 of Adherence to and usefulness of the national treatment guideline for urinary tract infections (UTI) in a risk area

Author

van Driel, A. A., Mulder, M., Stobberingh, E. E., and Verbon, A.

Abstract

Additional file 1: Supplementary Table 1. Percentages of uropathogens. Supplementary Table 2. Percentages of antibiotic resistance of E. coli in patients from the Westland area in comparison with data from studies of NIVEL 2004-2014 in the Netherlands

Published
2022
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17. A 12 year (1998–2009) antibiotic resistance surveillance of Klebsiella pneumoniae collected from intensive care and urology patients in 14 Dutch hospitals

Author

van der Donk, C. F. M., Beisser, P. S., Hoogkamp-Korstanje, J. A. A., Bruggeman, C. A., Stobberingh, E. E., Waar, K., Vogels, W. H. M., Bloembergen, P., Beunders, A. J., Rietra, P. J. G. M., Hendrix, M. G. R., Bijlmer, H. A., Dejongh, B. M., Hendriks, W. D. H., Sturm, P., Buiting, A. G. M., Sabbe, L. J. M., Trienekens, T. A. M., and van Dessel, H.

Published
2011
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