466 results on '"Stoilov P"'
Search Results
2. Investigating the Proton Structure: The FAMU experiment
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Vacchi, A., Adamczak, A., Bakalov, D., Baldazzi, G., Baruzzo, M., Benocci, R., Bertoni, R., Bonesini, M., Cabrera, H., Carsi, S., Cirrincione, D., Chignoli, F., Clemenza, M., Colace, L., Danailov, M., Danev, P., de Bari, A., De Vecchi, C., De Vincenzi, M., Fasci, E., Gadedjisso-Tossou, K. S., Gianfrani, L., Hillier, A. D., Ishida, K., King, P. J. C., Maggi, V., Mazza, R., Menegolli, A., Mocchiutti, E., Moretti, L., Morgante, G., Niemela, J., Petroselli, C., Pizzolotto, C., Pullia, A., Ramponi, R., Roman, H. E., Rossella, M., Rossini, R., Sarkar, R., Sbrizzi, A., Stoilov, M., Stoychev, L., Suarez-Vargas, J. J., Toci, G., Tortora, L., Vallazza, E., Xiao, C., and Yokoyama, K.
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Physics - Atomic Physics - Abstract
The article gives the motivations for the measurement of the hyperfine splitting (hfs) in the ground state of muonic hydrogen to explore the properties of the proton at low momentum transfer. It summarizes these proposed measurement methods and finally describes the FAMU experiment in more detail.
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- 2024
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3. Multi-domain spectral approach to rational-order fractional derivatives
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Klein, C. and Stoilov, N.
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Mathematics - Numerical Analysis ,Mathematics - Analysis of PDEs - Abstract
We propose a method to numerically compute fractional derivatives (or the fractional Laplacian) on the whole real line via Riesz fractional integrals. The compactified real line is divided into a number of intervals, thus amounting to a multi-domain approach; after transformations in accordance with the underlying $Z_{q}$ curve ensuring analyticity of the respective integrands, the integrals over the different domains are computed with a Clenshaw-Curtis algorithm. As an example, we consider solitary waves for fractional Korteweg-de Vries equations and compare these to results obtained with a discrete Fourier transform.
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- 2024
4. Status of the detector setup for the FAMU experiment at RIKEN-RAL for a precision measurement of the Zemach radius of the proton in muonic hydrogen
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Rossini, R., Adamczak, A., Bakalov, D., Baldazzi, G., Banfi, S., Baruzzo, M., Benocci, R., Bertoni, R., Bonesini, M., Bonvicini, V., Cabrera, H., Carsi, S., Cirrincione, D., Clemenza, M., Colace, L., Danailov, M. B., Danev, P., de Bari, A., de Vecchi, C., Fasci, E., Gadedjisso-Tossou, K. S., Gaigher, R., Gianfrani, L., Hillier, A. D., Ishida, K., King, P. J. C., Maggi, V., Menegolli, A., Mocchiutti, E., Moretti, L., Morgante, G., Niemela, J., Petroselli, C., Pirri, A., Pizzolotto, C., Prata, M. C., Pullia, A., Pullia, M., Ramponi, R., Rossella, M., Sarkar, R., Sbrizzi, A., Stoilov, M., Suarez-Vargas, J. J., Toci, G., Tortora, L., Vallazza, E. S., Yokoyama, K., and Vacchi, A.
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Physics - Atomic Physics ,High Energy Physics - Experiment - Abstract
The FAMU experiment at RIKEN-RAL is a muonic atom experiment with the aim to determine the Zemach radius of the proton by measuring the 1s hyperfine splitting in muonic hydrogen. The activity of the FAMU Collaboration in the years 2015-2023 enabled the final optimisation of the detector-target setup as well as the gas working condition in terms of temperature, pressure and gas mixture composition. The experiment has started its data taking in July 2023. The status of the detector setup for the 2023 experimental runs, for the beam characterisation and muonic X-ray detection in the 100-200 keV energy range, is presented and discussed., Comment: Submitted to JINST
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- 2023
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5. Survival of Chairside Posterior Single Crowns Made from InCoris TZI Zirconia—A Retrospective Analysis up to 10 Years
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Julius Jules Neuhöffer, Lea Stoilov, Norbert Enkling, Helmut Stark, Dominik Kraus, and Milan Stoilov
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3Y-TZP ,zirconia ,high-speed sintering ,ceramic ,chairside ,CEREC ,Medicine - Abstract
Objective: The aim of the present study was to evaluate the long-term clinical survival and success of chairside-fabricated single-tooth monolithic zirconia restorations on posterior teeth using the speed sintering process. Materials and Methods: Between 2012 and 2022, 250 single-tooth crowns were fabricated for 193 patients using the CEREC® chairside workflow. Restorations were fabricated from monolithic 3Y-TZP zirconia (InCoris TZI, Dentsply Sirona©, Bensheim, Germany) as full-contour crowns. The same clinician performed all procedures. Luting was performed using self-adhesive resin-based cements or glass ionomer cement. Retrospective analysis was conducted, defining survival as crowns still in function regardless of any interventions, and success as crowns that remained functional without the need for intervention. Statistical analysis was performed using Kaplan–Meier analysis, considering “refabrication” and “intervention” as endpoints. Results: Of the 250 crowns, a total of 162 (64.8%) crowns showed success. Over the whole observation period, 44 crowns (17.6%) required refabrication, and 88 (35.2%) required intervention. Mean survival without refabrication was 7.43 years, with a 5- and 7.5-year survival of 86.9% and 76.6%. The mean survival without intervention was 6.5 years, with a 5- and 7.5-year survival of 70.8% and 59.9%. Conclusions: Under appropriate technical conditions, chairside-fabricated 3Y-TZP zirconia single-tooth crowns represent a viable fabrication method. Neither the cementation mode nor the crown position—whether on premolars or molars—significantly impacted the survival rates.
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- 2024
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6. Aqueous humour interleukin-6 and vision outcomes with anti-vascular endothelial growth factor therapy
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Sepah, Yasir Jamal, Do, Diana V., Mesquida, Marina, Day, Bann-Mo, Blotner, Steven, Afridi, Rubbia, Halim, Muhammad Sohail, Hong, Kyu, Wakshull, Eric, Fauser, Sascha, Stoilov, Ivaylo, and Dong Nguyen, Quan
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- 2024
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7. Experimental determination of the energy dependence of the rate of the muon transfer reaction from muonic hydrogen to oxygen for collision energies up to 0.1 eV
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Stoilov, M., Adamczak, A., Bakalov, D., Danev, P., Mocchiutti, E., Pizzolotto, C., Baldazzi, G., Baruzzo, M., Benocci, R., Bonesini, M., Cirrincione, D., Clemenza, M., Fuschino, F., Hillier, A. D., Ishida, K., King, P. J. C., Menegolli, A., Monzani, S., Ramponi, R., Rignanese, L. P., Sarkar, R., Sbrizzi, A., Tortora, L., Vallazza, E., and Vacchi, A.
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Physics - Atomic Physics - Abstract
We report the first experimental determination of the collision-energy dependence of the muon transfer rate from the ground state of muonic hydrogen to oxygen at near-thermal energies. A sharp increase by nearly an order of magnitude in the energy range 0 - 70 meV was found that is not observed in other gases. The results set a reliable reference for quantum-mechanical calculations of low-energy processes with exotic atoms, and provide firm ground for the measurement of the hyperfine splitting in muonic hydrogen and the determination of the Zemach radius of the proton by the FAMU collaboration., Comment: 30 pages, 10 figures
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- 2023
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8. Forest Operations Using a Combi–Forwarder in Deciduous Forests
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Stoilov, Stanimir, Proto, Andrea Rosario, Oslekov, Delyan, Angelov, Georgi, and Papandrea, Salvatore Francesco
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- 2024
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9. Bioimpedance analysis for fluid status assessment in critically ill septic patients
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Emral Kyosebekirov, Dimitar Kazakov, Siyana Nikolova-Kamburova, Valentin Stoilov, Emil Mitkovski, Georgi Pavlov, Chavdar Stefanov, and Angelina Mollova-Kyosebekirova
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Medicine - Abstract
Aim: The aim of this study was to assess the usefulness of bioimpedance analysis in fluid status evaluation in patients with sepsis and septic shock admitted to the adult ICU. Materials and methods: This is a prospective, observational, clinician-blind study. The inclusion criteria were a diagnosis of sepsis at admission to ICU, a stay in ICU of at least 72 hours, and the first BIA measurement to be conducted within the first three hours of ICU admission. We took whole-body BIA measurements upon admission and every 24 hours thereafter for at least four consecutive measurements. All enteral and parenteral fluids administered to the patients were recorded, as well as the loses through drains, tubes, aspiration, and urine. The cumulative fluid balance (CFB) was calculated every 24 hours. Results: A total of 51 patients with a mean age of 62 years were included in the final analysis. CFB gradually increased during the first 72 hours of ICU stay from 2003±1331 mL at 24 hours to 3680±2368 mL at 48 hours and 5217±2642 mL at 72 hours. There was a statistically significant positive correlation between the increase in CFB and the increase in total body water, extracellular water, and overhydration. The daily changes of vector length and impedance ratio, as well as the overall 72-hour changes showed statistically significant correlation with the CFB. Conclusion: Bioimpedance analysis is a non-invasive, easy-to-use, inexpensive, portable, and fast tool for fluid status assessment. In critically ill septic patients it can be a useful tool in fluid therapy management.
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- 2024
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10. Numerical study of the transverse stability of line solitons of the Zakharov-Kuznetsov equations
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Klein, Christian, Saut, Jean-Claude, and Stoilov, Nikola
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Mathematics - Analysis of PDEs ,Nonlinear Sciences - Pattern Formation and Solitons - Abstract
We present a detailed numerical study of the stability under periodic perturbations of line solitons of two-dimensional, generalized Zakharov-Kuznetsov equations with various power nonlinearities. In the $L^{2}$-subcritical case, in accordance with a theorem due to Yamazaki we find a critical speed, below which the line soliton is stable. For higher velocities, the numerical results indicate an instability against the formation of lumps, solitons localized in both spatial directions. In the $L^2$-critical and supercritical cases but subcritical for the 1D generalized Korteweg-de Vries equation), the line solitons are shown to be numerically stable for small velocities, and strongly unstable for large velocities, with a blow-up observed in finite time., Comment: New figures added
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- 2022
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11. Large $|k|$ behavior for the reflection coefficient for Davey-Stewartson II equations
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Klein, Christian, Sjöstrand, Johannes, and Stoilov, Nikola
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Mathematics - Analysis of PDEs ,Mathematical Physics ,Nonlinear Sciences - Exactly Solvable and Integrable Systems - Abstract
The study of complex geometric optics solutions to a system of d-bar equations appearing in the context of electrical impedance tomography and the scattering theory of the integrable Davey-Stewartson II equations for large values of the spectral parameter $k$ in \cite{KlSjSt20} is extended to the reflection coefficient. For the case of potentials $q$ with compact support on some domain $\Omega$ with smooth strictly convex boundary, improved asymptotic relations are provided.
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- 2022
12. Efficacy of Virtual Preparation Simulators Compared to Traditional Preparations on Phantom Heads
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Lea Stoilov, Fabian Stephan, Helmut Stark, Norbert Enkling, Dominik Kraus, and Milan Stoilov
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dental education ,digital dentistry ,SIMtoCARE ,virtual simulation ,HVRS ,Dentistry ,RK1-715 - Abstract
Background: Virtual simulators are increasingly being introduced in dental education. This study investigates whether virtual simulators offer comparable or superior educational efficacy when compared to traditional phantom simulators. Materials and Methods: Participants were randomly allocated into groups: Virtual Preparation (SIM; n = 30) and Traditional Preparation (FRA; n = 30). Students were tasked with preparing tooth 36 for a full-cast crown during free practice for four days. Faculty staff provided feedback to both groups. Examinations were administered and graded by three examiners (preclinical and clinical consultants and a dental surgery consultant). Additionally, a survey was conducted to assess each training concept. Results: The FRA group achieved significantly better grades in the preparation exam evaluations by all three examiners, compared to the SIM group. Interrater reliability showed only moderate agreement, with the clinical examiner giving better grades than the other two. The questionnaire results indicate that while participants managed with the virtual system, they preferred the analog system for exams and patient preparation. Conclusion: Virtual simulators do not seem to be as good when it comes to practicing for a preparation exam or clinical preparation, especially for unexperienced students. However, they still appear to be useful as an additional tool for introducing students to the topic of preparation.
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- 2024
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13. Spectral approach to Korteweg-de Vries equations on the compactified real line
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Klein, C. and Stoilov, N.
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Mathematics - Numerical Analysis ,Nonlinear Sciences - Exactly Solvable and Integrable Systems - Abstract
We present a numerical approach for generalised Korteweg-de Vries (KdV) equations on the real line. In the spatial dimension we compactify the real line and apply a Chebyshev collocation method. The time integration is performed with an implicit Runge-Kutta method of fourth order. Several examples are discussed: initial data bounded but not vanishing at infinity as well as data not satisfying the Faddeev condition, i.e. with a slow decay towards infinity.
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- 2021
14. Correction: An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing.
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Raymond W Wong, Ahalya Balachandran, Peter K Cheung, Ran Cheng, Qun Pan, Peter Stoilov, P Richard Harrigan, Benjamin J Blencowe, Donald R Branch, and Alan Cochrane
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Immunologic diseases. Allergy ,RC581-607 ,Biology (General) ,QH301-705.5 - Abstract
[This corrects the article DOI: 10.1371/journal.ppat.1008307.].
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- 2024
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15. Numerical study of Davey-Stewartson I systems
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Frauendiener, J., Klein, C., Muhammad, U., and Stoilov, N.
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Mathematics - Analysis of PDEs ,Nonlinear Sciences - Exactly Solvable and Integrable Systems - Abstract
An efficient high precision hybrid numerical approach for integrable Davey-Stewartson (DS) I equations for trivial boundary conditions at infinity is presented for Schwartz class initial data. The code is used for a detailed numerical study of DS I solutions in this class. Localized stationary solutions are constructed and shown to be unstable against dispersion and blow-up. A finite-time blow-up of initial data in the Schwartz class of smooth rapidly decreasing functions is discussed.
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- 2021
16. Europe and the War in Ukraine: Support, Degree of Participation or Neutrality
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Yanaki Stoilov
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eu ,international governance ,ukraine ,war ,International relations ,JZ2-6530 - Abstract
The text critically examines the intricate interplay between politics, ideology, and law within the ongoing war in Ukraine. The primary aim is to comprehensively assess the multifaceted implications of the conflict for Europe’s position in the evolving global context. Through the presentation of ten key points, the author explores various topics, including the erosion of sovereignty due to the Russian intervention, the absence of formal war declarations, and the far-reaching consequences of the conflict on a global scale. Additionally, the discourse delves into the crisis facing the international legal order, the emergence of a more complex bipolar world, and the expansion of EU law at the expense of national legislation.
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- 2023
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17. Comparative characteristics of some methods for estimating energy expenditure in critically ill mechanically ventilated patients
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Siyana Nikolova, Emral Kyosebekirov, Emil Mitkovski, Dimitar Kazakov, Valentin Stoilov, Georgi Pavlov, and Chavdar Stefanov
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Medicine - Abstract
Aim: To compare the energy expenditure (EE) assessed by ventilator-derived carbon dioxide production (EE–VCO2-ventilator) and the energy expenditure calculated from six predictive equations with the gold standard energy expenditure measured with indirect calorimetry (IC) in mechanically ventilated patients. Materials and methods: This is a prospective, non-randomized, one-month study which included six mechanically ventilated patients with FiO2
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- 2023
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18. Measurement of the muon transfer rate from muonic hydrogen to oxygen in the range 70-336 K
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Pizzolotto, C., Sbrizzi, A., Adamczak, A., Bakalov, D., Baldazzi, G., Baruzzo, M., Benocci, R., Bertoni, R., Bonesini, M., Cabrera, H., Cirrincione, D., Clemenza, M., Colace, L., Danailov, M., Danev, P., de Bari, A., De Vecchio, C., De Vincenzi, M., Fasci, E., Fuschino, F., Gadedjisso-Tossou, K. S., Gianfrani, L., Ishida, K., Labanti, C., Maggi, V., Mazza, R., Menegolli, A., Mocchiutti, E., Monzani, S., Moretti, L., Morgante, G., Niemela, J., Pullia, A., Ramponi, R., Rignanese, L. P., Rossella, M., Stoilov, M., Stoychev, L., Suarez-Vargas, J. J., Tortora, L., Vallazza, E., and Vacchi, A.
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Physics - Atomic Physics - Abstract
The first measurement of the temperature dependence of the muon transfer rate from muonic hydrogen to oxygen was performed by the FAMU collaboration in 2016. The results provide evidence that the transfer rate rises with the temperature in the range 104-300 K. This paper presents the results of the experiment done in 2018 to extend the measurements towards lower (70 K) and higher (336 K) temperatures. The 2018 results confirm the temperature dependence of the muon transfer rate observed in 2016 and sets firm ground for comparison with the theoretical predictions.
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- 2021
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19. Multi-domain spectral approach for the Hilbert transform on the real line
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Klein, C., Riton, J., and Stoilov, N.
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Mathematics - Numerical Analysis ,Nonlinear Sciences - Pattern Formation and Solitons - Abstract
A multi-domain spectral method is presented to compute the Hilbert transform on the whole compactified real line, with a special focus on piece-wise analytic functions and functions with algebraic decay towards infinity. Several examples of these and other types of functions are discussed. As an application solitons to generalized Benjamin-Ono equations are constructed.
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- 2021
20. Antibacterial Electrospun Membrane with Hierarchical Bead-on-String Structured Fibres for Wound Infections
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Yu Xuan Fong, Catherine Pakrath, Fathima Shana Pattar Kadavan, Tien Thanh Nguyen, Trong Quan Luu, Borislav Stoilov, Richard Bright, Manh Tuong Nguyen, Neethu Ninan, Youhong Tang, Krasimir Vasilev, and Vi Khanh Truong
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nanofibres ,polycaprolactone ,silk sericin ,biocompatible ,biodegradable ,natural polymer ,Chemistry ,QD1-999 - Abstract
Chronic wounds often result in multiple infections with various kinds of bacteria and uncontrolled wound exudate, resulting in several healthcare issues. Advanced medicated nanofibres prepared by electrospinning have gained much attention for their topical application on infected chronic wounds. The objective of this work is to enhance the critical variables of ciprofloxacin-loaded polycaprolactone-silk sericin (PCL/SS-PVA-CIP) nanofibre production via the process of electrospinning. To examine the antibacterial effectiveness of PCL/SS-PVA-CIP nanocomposites, the material was tested against P. aeruginosa and S. aureus. The combination of PCL/SS-PVA-CIP exhibited potent inhibitory properties, with the most effective concentrations of ciprofloxacin (CIP) being 3 μg/g and 7.0 μg/g for each bacterium, respectively. The biocompatibility was evaluated by conducting cell reduction and proliferation studies using the human epidermal keratinocyte (HaCaT) cells and human gingival fibroblasts (HGFs) in vitro cell lines. The PCL/SS-PVA-CIP showed good cell compatibility with HaCaT and HGF cells, with effective proliferation even at antibiotic doses of up to 7.0 μg/g. The drug release effectiveness of the nanocomposites was assessed at various concentrations of CIP, resulting in a maximum cumulative release of 76.5% and 74.4% after 72 h for CIP concentrations of 3 μg/g and 7 μg/g, respectively. In summary, our study emphasizes the possibility of combining silk sericin (SS) and polycaprolactone (PCL) loading with CIP nanocomposite for wound management.
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- 2024
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21. Numerical study of soliton stability, resolution and interactions in the 3D Zakharov-Kuznetsov equation
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Klein, C., Roudenko, S., and Stoilov, N.
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Mathematics - Analysis of PDEs ,Mathematics - Numerical Analysis - Abstract
We present a detailed numerical study of solutions to the Zakharov-Kuznetsov equation in three spatial dimensions. The equation is a three-dimensional generalization of the Korteweg-de Vries equation, though, not completely integrable. This equation is $L^2$-subcritical, and thus, solutions exist globally, for example, in the $H^1$ energy space. We first study stability of solitons with various perturbations in sizes and symmetry, and show asymptotic stability and formation of radiation, confirming the asymptotic stability result in \cite{FHRY2020} for a larger class of initial data. We then investigate the solution behavior for different localizations and rates of decay including exponential and algebraic decays, and give positive confirmation toward the soliton resolution conjecture in this equation. Finally, we investigate soliton interactions in various settings and show that there is both a quasi-elastic interaction and a strong interaction when two solitons merge into one, in all cases always emitting radiation in the conic-type region of the negative $x$-direction.
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- 2020
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22. Large $|k|$ behavior of d-bar problems for domains with a smooth boundary
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Klein, C., Sjöstrand, Johannes, and Stoilov, N.
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Mathematics - Analysis of PDEs - Abstract
In a previous work on the large $|k|$ behavior of complex geometric optics solutions to a system of d-bar equations, we treated in detail the situation when a certain potential is the characteristic function of a strictly convex set with real-analytic boundary. We here extend the results to the case of sets with smooth boundary, by using almost holomorphic functions.
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- 2020
23. Multidomain spectral approach with Sommerfeld condition for the Maxwell equations
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Klein, C and Stoilov, N.
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Mathematics - Numerical Analysis - Abstract
We present a multidomain spectral approach with an exterior compactified domain for the Maxwell equations for monochromatic fields. The Sommerfeld radiation condition is imposed exactly at infinity being a finite point on the numerical grid. As an example, axisymmetric situations in spherical and prolate spheroidal coordinates are discussed., Comment: Examples added
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- 2020
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24. Large $|k|$ behavior of complex geometric optics solutions to d-bar problems
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Klein, C., Sjöstrand, J., and Stoilov, N.
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Mathematics - Analysis of PDEs ,Mathematical Physics ,Nonlinear Sciences - Exactly Solvable and Integrable Systems - Abstract
Complex geometric optics solutions to a system of d-bar equations appearing in the context of electrical impedance tomography and the scattering theory of the integrable Davey-Stewartson II equations are studied for large values of the spectral parameter $k$. For potentials \( q\in \langle \cdot \rangle^{-2} H^{s}(\mathbb{C}) \) for some $s \in]1,2]$, it is shown that the solution converges as the geometric series in $1/|k|^{s-1}$. For potentials $q$ being the characteristic function of a strictly convex open set with smooth boundary, this still holds with $s=3/2$ i.e., with $1/\sqrt{|k|}$ instead of $1/|k|^{s-1}$. The leading order controbutions are computed explicitly. Numerical simulations show the applicability of the asymptotic formulae for the example of the characteristic function of the disk., Comment: references updated
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- 2020
25. A classical attack on the coherent one way protocol for quantum key distribution
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Stoilov, Michail
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Quantum Physics - Abstract
We propose a way to retrieve the secure key generated by the coherent one way protocol without reading the information transmitted on the quantum channel., Comment: 6 pages, LaTeX, 1 figure. References added
- Published
- 2020
26. Numerical study of Zakharov-Kuznetsov equations in two dimensions
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Klein, C., Roudenko, S., and Stoilov, N.
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Mathematics - Analysis of PDEs ,Mathematics - Numerical Analysis - Abstract
We present a detailed numerical study of solutions to the (generalized) Zakharov-Kuznetsov equation in two spatial dimensions with various power nonlinearities. In the $L^{2}$-subcritical case, numerical evidence is presented for the stability of solitons and the soliton resolution for generic initial data. In the $L^2$-critical and supercritical cases, solitons appear to be unstable against both dispersion and blow-up. It is conjectured that blow-up happens in finite time and that blow-up solutions have some resemblance of being self-similar, i.e., the blow-up core forms a rightward moving self-similar type rescaled profile with the blow-up happening at infinity in the critical case and at a finite location in the supercritical case. In the $L^{2}$-critical case, the blow-up appears to be similar to the one in the $L^{2}$-critical generalized Korteweg-de Vries equation with the profile being a dynamically rescaled soliton.
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- 2020
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27. Quality of life and disease activity of patients with rheumatoid arthritis on tofacitinib and biologic disease-modifying antirheumatic drug therapies
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Boyadzhieva, Vladimira, Tachkov, Konstantin, Stoilov, Nikolay, Mitov, Konstantin, Stoilov, Rumen, and Petrova, Guenka
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- 2022
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28. Independent predictors of preeclampsia and their impact on the complication in Bulgarian study group of pregnant women
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Boris Stoilov, Polina Zaharieva-Dinkova, Lili Stoilova, Ekaterina Uchikova, and Emiliya Karaslavova
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Medicine - Abstract
Introduction: One of the major obstetrical complications, affecting 2%–8% of all pregnancies, is preeclampsia. To predict the onset of preeclampsia, several methods have recently been put forth. The Fetal Medicine Foundation has developed combined screening that can identify the vast majority of women who will develop preeclampsia using a combination of maternal factors, obstetrical history, biochemical, and biophysical factors. Aim: The objective of the present study was to identify and analyze which classical risk factors may be independent predictors of preeclampsia, and assess their impact on this complication. In order to assess the high risk of preeclampsia, we also suggest further predictors that may optimize the risk constellation. Materials and methods: The study included 1511 pregnant women who were examined during their routine checkups in a two-phase retrospective study that took place from January 30, 2018, to August 31, 2020, in the Outpatient Department of the University Hospital in Plovdiv. All primary data were obtained from their archived medical records. Information about the maternal factors, the patients’ medical and obstetric histories, and status was obtained during the first phase of the study (11th gestation week + 0 days – 13th gestation week + 6 days). The second phase was conducted as a telephone interview (up to six months after the birth of the child): we collected data on the mode of birth, weight of the newborn, PE occurrence, at which gestation week the PE onset occurred, presence of gestational hypertension (GH) and diabetes, intrauterine growth retardation (IUGR), whether patients took aspirin and in what dosage, other complications, etc. The patients were divided into two groups: a high-risk group (with a risk for PE higher than 1:150), and a low-risk group, with or without onset of IUGR, GH, diabetes, etc. Results: The mean age of the analyzed 1511 pregnant women was 29.91±5.32 years (range 18 – 46 years). Of these, 38 (2.9%) women developed preeclampsia, and 5.9% had gestational hypertension. The classification of participants by risk of developing preeclampsia showed that 591 (39.1%) of the examined patients were reported as high-risk. All patients at risk higher than 1:150 were classified as high-risk, and it was recommended that they should take aspirin 150 mg every night from 12th to 36th week of gestation. 80.6% of the high-risk group took the medication regularly. Comparing the beta coefficients for the parameters we studied (beta coefficient indicates the predictors’ impact on PE), we established that the risk factors that are the most significant and apparently independent in predicting preeclampsia were (in ascending order): 1. Weight of newborn, β=0.157; 2. Mean arterial blood pressure (MAP), β=0.150; 3. IUGR, β=0.120; 4. Pregnancy associated plasma protein-A (PAPP-A), β=0.112; 5. Cervix length, β=0.095 Conclusions: In the analysis of the four multiple regression models, adequately describing the role (and independence) of the PE predictors – common to all pregnant women; in cases of early midterm and term PE: placental growth factor (PlGF), PAPP-A, MAP, mean Ut PI, cervical length, newborn weight, and IUGR. As common for all cases with PE, and depending on whether the PE onset was ≤32, ≤4, or ≤36 week of gestation, the following conclusions can be made: independent predictors of PE in all studied pregnant women were (indicators are ranked according to their degree of impact on the occurrence of PE): 1. MAP; 2. Intrauterine growth retardation (newborn weight is an indirect indicator of probable IUGR); 3. Pregnancy-associated protein-A; 4. Cervix length (with the corresponding standardized coefficients being β=0.150; β=0.120; β=0.112; β=0.095, respectively).
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- 2023
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29. Model for Reinvestment Policy in Risk-Free Assets with Various Maturities
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Stoilov T., Stoilova K., and Kanev D.
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investment management ,portfolio reinvestment ,optimization ,decision making ,Cybernetics ,Q300-390 - Abstract
Logistic tasks are aimed at the optimal distribution of material, energy, financial and human resources. This research has a narrow field aimed at optimal management of financial resources and their redistribution. Specifically, a reinvestment policy model is derived by maximizing the profit of a business entity. Reinvestment is done with risk-free assets, but they have different maturity periods. This makes it difficult to assess the optimal investment strategy, as reinvestment can be done at the end of the maturity period. This study develops a model for a dynamic control process, which leads to the formalization of a discrete integer time optimization problem. Its solution gives a sequence of investments and a total optimal return. The solution to the problem is illustrated in an EXCEL environment. The added value of this study stems from the formalization and quantification of the model for the reinvestment strategy in the optimization problem.
- Published
- 2023
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30. High precision numerical approach for the Davey-Stewartson II equation for Schwartz class initial data
- Author
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Klein, C., McLaughlin, K., and Stoilov, N.
- Subjects
Mathematics - Numerical Analysis ,Nonlinear Sciences - Exactly Solvable and Integrable Systems - Abstract
We present an efficient high-precision numerical approach for the Davey-Stewartson (DS) II equation, treating initial data from the Schwartz class of smooth, rapidly decreasing functions. As with previous approaches, the presented code uses discrete Fourier transforms for the spatial dependence and Driscoll's composite Runge-Kutta method for the time dependence. Since the DS equation is a nonlocal, nonlinear Schr\"odinger equation with a singular symbol for the nonlocality, standard Fourier methods in practice only reach accuracies of the order of $10^{-6}$ or less for typical examples. This was previously demonstrated for the defocusing case by comparison with a numerical approach for DS via inverse scattering. By applying a regularization to the singular symbol, originally developed for D-bar problems, the presented code is shown to reach machine precision. The code can treat integrable and non-integrable DS II equations. Moreover, it has the same %complexity numerical complexity as existing codes for DS II. Several examples for the integrable defocusing DS II equation are discussed as test cases. In an appendix by C.~Kalla, a doubly periodic solution to the defocusing DS II equation is presented, providing a test for direct DS codes based on Fourier methods.
- Published
- 2019
- Full Text
- View/download PDF
31. Numerical study of the transverse stability of the Peregrine solution
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Klein, C. and Stoilov, N.
- Subjects
Mathematics - Numerical Analysis ,Mathematics - Analysis of PDEs ,Nonlinear Sciences - Exactly Solvable and Integrable Systems - Abstract
We generalise a previously published approach based on a multi-domain spectral method on the whole real line in two ways: firstly, a fully explicit 4th order method for the time integration, based on a splitting scheme and an implicit Runge--Kutta method for the linear part, is presented. Secondly, the 1D code is combined with a Fourier spectral method in the transverse variable both for elliptic and hyperbolic NLS equations. As an example we study the transverse stability of the Peregrine solution, an exact solution to the one dimensional nonlinear Schr\"odinger (NLS) equation and thus a $y$-independent solution to the 2D NLS. It is shown that the Peregrine solution is unstable against all standard perturbations, and that some perturbations can even lead to a blow-up for the elliptic NLS equation., Comment: Hyperbolic case added
- Published
- 2019
32. Cosmology from multimeasure multifield model
- Author
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Staicova, Denitsa and Stoilov, Michail
- Subjects
General Relativity and Quantum Cosmology - Abstract
We consider the cosmological application of a (variant of) relatively newly proposed model \cite{1609.06915} unifying inflation, dark energy, dark matter, and the Higgs mechanism. The model was originally defined using additional non-Riemannian measures but it can be reformulated into effective quintessential model unifying inflation, dark energy and dark matter. Here we demonstrate numerically that it is capable of describing the entire Universe evolution in a seamless way, but this requires some revision of the model setup. The main reason is that there is a strong effective friction in the model, a feature which has been neglected in the pioneer work. This improves the model potential for proper description of the Universe evolution, because the friction ensures a finite time inflation with dynamically maintained low-value slow-roll parameters in the realistic scenarios. In addition, the model predicts the existence of a constant scalar field in late Universe., Comment: 17 pages, 6 figures, accepted for publication in International Journal of Modern Physics A
- Published
- 2019
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- View/download PDF
33. First measurement of the temperature dependence of muon transfer rate from muonic hydrogen atoms to oxygen
- Author
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FAMU Collaboration, Mocchiutti, E., Adamczak, A., Bakalov, D., Baldazzi, G., Benocci, R., Bertoni, R., Bonesini, M., Bonvicini, V., Morales, H. Cabrera, Chignoli, F., Clemenza, M., Colace, L., Danailov, M., Danev, P., de Bari, A., De Vecchi, C., De Vincenzi, M., Furlanetto, E., Fuschino, F., Gadedjisso-Tossou, K. S., Guffanti, D., Ishida, K., Labanti, C., Maggi, V., Mazza, R., Menegolli, A., Morgante, G., Nastasi, M., Niemela, J., Pizzolotto, C., Pullia, A., Ramponi, R., Rignanese, L. P., Rossella, M., Rossi, N., Stoilov, M., Stoychev, L., Tortora, L., Vallazza, E., Zampa, G., and Vacchi, A.
- Subjects
Nuclear Experiment ,Physics - Instrumentation and Detectors - Abstract
We report the first measurement of the temperature dependence of muon transfer rate from $\mu$p atoms to oxygen between 100 and 300 K. Data were obtained from the X-ray spectra of delayed events in gaseous target H$_2$/O$_2$ exposed to a muon beam. Based on the data, we determined the muon transfer energy dependence up to 0.1 eV, showing an 8-fold increase in contrast with the predictions of constant rate in the low energy limit. This work set constraints on theoretical models of muon transfer, and is of fundamental importance for the measurement of the hyperfine splitting of $\mu$p by the FAMU collaboration., Comment: 11 pages, 4 figure
- Published
- 2019
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- View/download PDF
34. Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon.
- Author
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Lin, Lin, Zhang, Min, Stoilov, Peter, Chen, Liang, and Zheng, Sika
- Subjects
AS-NMD ,BAK ,BCL2 family proteins ,NMD ,PTB ,PTBP ,PTBP2 ,UPF2 ,alternative splicing ,cell death ,neural development ,neurogenesis ,neuronal lifespan ,Animals ,Apoptosis ,Brain ,Cell Line ,Tumor ,Cells ,Cultured ,Female ,Heterogeneous-Nuclear Ribonucleoproteins ,Male ,Mice ,Mice ,Inbred C57BL ,Mutation ,Neural Stem Cells ,Neurogenesis ,Nonsense Mediated mRNA Decay ,Polypyrimidine Tract-Binding Protein ,RNA Splicing ,bcl-2 Homologous Antagonist-Killer Protein - Abstract
Continuous neuronal survival is vital for mammals because mammalian brains have limited regeneration capability. After neurogenesis, suppression of apoptosis is needed to ensure a neurons long-term survival. Here we describe a robust genetic program that intrinsically attenuates apoptosis competence in neurons. Developmental downregulation of the splicing regulator PTBP1 in immature neurons allows neural-specific splicing of the evolutionarily conserved Bak1 microexon 5. Exon 5 inclusion triggers nonsense-mediated mRNA decay (NMD) and unproductive translation of Bak1 transcripts (N-Bak mRNA), leading to suppression of pro-apoptotic BAK1 proteins and allowing neurons to reduce apoptosis. Germline heterozygous ablation of exon 5 increases BAK1 proteins exclusively in the brain, inflates neuronal apoptosis, and leads to early postnatal mortality. Therefore, neural-specific exon 5 splicing and depletion of BAK1 proteins uniquely repress neuronal apoptosis. Although apoptosis is important for development, attenuation of apoptosis competence through neural-specific splicing of the Bak1 microexon is essential for neuronal and animal survival.
- Published
- 2020
35. Cost of arthropathic diseases therapy with biologicals disease modifying drugs (bDMARs): a 5-year cost analysis at national level
- Author
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Konstantin Tachkov, Vladimira Boyadzhieva, Ivan Manev, Nikolay Stoilov, Zornitsa Mitkova, Konstantin Mitov, and Guenka Petrova
- Subjects
Biological medicines ,arthropathic diseases ,cost of therapy ,diseases modifying antirheumatic medicines ,Biotechnology ,TP248.13-248.65 - Abstract
AbstractThis study analysed the changes in the reimbursed cost, prices and utilization of biological medicines for a 5-year time horizon, encompassing three major arthropathic diagnoses, rheumatoid arthritis (RA), psoriatic arthropathies (PsA) and ankylosing spondylitis (AS), from the point of view of the third-party payer in Bulgaria. National; population based; macroeconomic; top-down budget analysis was performed based on official data about the number of inhabitants, reimbursed diagnoses and medicines, reimbursed cost, treated patients, and prices of medicines. The utilization of medicines was calculated in DDD per 1000/inh/day. There was an increase of 41% in the number of patients treated with biological medicines. The reimbursement cost of biologicals increased by 21%; however, the per-patient reimbursement costs per diagnosis fell by 40% due to price decreases. Out of 21 reimbursed diagnoses, we saw a significant difference in prevalence (612 SD in 2016 to 1216 SD in 2020; p
- Published
- 2022
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36. A Rare Case of Anca Positivity and Antiphospholipid Antibodies in a Patient with Takayasu Arteritis: Case Report and Review of the Literature
- Author
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Rositsa Dacheva, Ekaterina Kurteva, Vladimira Boyadzhieva, Rumen Stoilov, Dobroslav Kyurkchiev, and Nikolay Stoilov
- Subjects
antiphospholipid antibodies ,Takayasu arteritis ,ANCA ,Biology (General) ,QH301-705.5 - Abstract
Takayasu arteritis (TA) is a chronic large-vessel vasculitis characterized by immune-mediated panarteritis, which predominantly affects the aorta and its main branches and is most prevalent in young women. TA is unusually associated with the presence of antiphospholipid antibodies. We present a case report of a 48-year-old Caucasian woman with acute aortic dissection as an initial feature of TA, where detailed clinical, imaging and laboratory studies were performed. Computed tomography angiography (CTA) of the chest and abdomen revealed aortic dissection DeBakey I. Bentall and De Bono surgery was performed. Additional immunological tests revealed positive antineutrophil cytoplasmic antibodies (ANCAs) with the simultaneous presence of pANCA and cANCA antibodies on indirect immunofluorescence, along with anti-MPO+PR3+antibodies positivity in the absence of a clinically relevant disease. Surprisingly, antiphospholipid antibodies (aPLs) were detected. Then, we performed a thorough review of the current literature. The coexistence of aPL antibodies and dual specificity for MPO and PR3 in a patient diagnosed with Takayasu arteritis is unusual and poses a diagnostic challenge. The presented case report outlines a rare case of aortic dissection as a presenting symptom of TA, along with atypical ANCA positivity and positive APL antibodies.
- Published
- 2023
- Full Text
- View/download PDF
37. Productivity analysis and costs of wheel cable skidder during salvage logging in European beech stand
- Author
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Stanimir Stoilov, Salvatore F. Papandrea, Georgi Angelov, Delyan Oslekov, Giuseppe Zimbalatti, and Andrea R. Proto
- Subjects
Post-disturbance ,damaged timber ,forest operation ,timber harvesting ,ground-based systems ,Agriculture ,Agriculture (General) ,S1-972 - Abstract
Salvage logging is increasing in Central Europe because of the growth of severe meteorological events, and timber harvesting in these conditions is challenging in terms of both productivity performances and safety of the operations. In recent years, with the increase of natural calamities, several researchers studied machinery productivity performances regarding salvage logging carried out by ground-based systems. In fact, a common post-disturbance management approach is salvage logging which consists of the widespread removal of damaged trees. In this research, system productivity and the cost of salvage logging are analysed in European beech stands affected by wet snow. The accretion of heavy wet snow poses the greatest risk to forests in the Northern Hemisphere. This type of snow attaches more effectively to tree crowns and branches when temperatures are close to freezing at the time of precipitation. As a result, trees may break or bend and may be uprooted when the soil is unfrozen. This study has been implemented to evaluate the productivity and cost-effectiveness of extraction in salvage logging deployed with a skidder in beech stands affected by two different types of wet snow damage. The results show that the productivity of the four-wheel-drive cable skidder, despite operating in salvage cutting with a removal intensity of 10%, is 14.73 m3·SMH–1, similar to skidder performances in ‘ordinary’ cuttings. Skidder’s productive time was 86% of the scheduled time, whereas the delays were due to organisational reasons, mechanical delays, and adverse weather conditions. The mean travel speed of the cable skidder obtained in this study is close to the results obtained from other studies on similar machines. The costs per unit are lower than effective cost consumptions for the other cable skidders and agricultural tractors, adapted for skidding operated in hardwood salvage logging. Therefore, under the given conditions, the operation of the fourwheel-drive cable skidder is viable from a silvicultural, technical, and economic point of view in the salvage operation logging.
- Published
- 2023
- Full Text
- View/download PDF
38. Analysis of Lateral Forces for Assessment of Safety against Derailment of the Specialized Train Composition for the Transportation of Long Rails
- Author
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Valeri Stoilov, Petko Sinapov, Svetoslav Slavchev, Vladislav Maznichki, and Sanel Purgic
- Subjects
railway ,derailment ,long rails transportation ,FEM ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
This study proposes a theoretical method for evaluating the “safety against derailment” indicator of a specialized train composition for the transportation of very long rails. A composition of nine wagons, suitable for the transportation of rails with a length of 120 m in three layers, is considered. For the remaining recommended rail lengths, the number of wagons is reduced or increased, with the calculation model being modified depending on the required configuration. When the composition is in a curve with the minimum radius (R = 150 m), the rails bend, and some of them come into contact with the vertical stanchions of the wagon and cause additional lateral forces. These forces are then transferred through the wagon body, central pivot, bogie frame, and wheels and act on the wheel–rail contact points. They could potentially lead to derailment of the train composition. The goal of this study is to determine the additional lateral forces that arise because of the bent rails. For the purposes of this study, the finite element method was used. Based on the displacements of the support points of the rails (caused by the geometry of the curve), the bending line of the elastic load is determined and the forces in the supports are calculated. The resulting forces are considered when determining the derailment safety criterion. The analysis of the results shows that the wagon with fixing blocks is the most at risk of derailment. The front and intermediate wagons have criterion values very close to that of the empty wagon. This shows that the emerging horizontal elastic forces do not significantly influence the derailment process. The obtained results show that the transportation of long rails with specialized train composition can be realized on four layers. This will significantly increase the efficiency of delivering new long rails.
- Published
- 2024
- Full Text
- View/download PDF
39. Multidomain spectral method for the Gauss hypergeometric function
- Author
-
Crespo, S., Fasondini, M., Klein, C., Stoilov, N., and Vallée, C.
- Subjects
Mathematics - Numerical Analysis - Abstract
We present a multidomain spectral approach for Fuchsian ordinary differential equations in the particular case of the hypergeometric equation. Our hybrid approach uses Frobenius' method and Moebius transformations in the vicinity of each of the singular points of the hypergeometric equation, which leads to a natural decomposition of the real axis into domains. In each domain, solutions to the hypergeometric equation are constructed via the well-conditioned ultraspherical spectral method. The solutions are matched at the domain boundaries to lead to a solution which is analytic on the whole compactified real line $\mathbb{R}\cup {\infty}$, except for the singular points and cuts of the Riemann surface on which the solution is defined. The solution is further extended to the whole Riemann sphere by using the same approach for ellipses enclosing the singularities. The hypergeometric equation is solved on the ellipses with the boundary data from the real axis. This solution is continued as a harmonic function to the interior of the disk by solving the Laplace equation in polar coordinates with an optimal complexity Fourier--ultraspherical spectral method.
- Published
- 2018
40. Spectral approach to the scattering map for the semi-classical defocusing Davey-Stewartson II equation
- Author
-
Klein, C., McLaughlin, K., and Stoilov, N.
- Subjects
Mathematics - Numerical Analysis ,Nonlinear Sciences - Exactly Solvable and Integrable Systems - Abstract
The inverse scattering approach for the defocusing Davey-Stewartson II equation is given by a system of D-bar equations. We present a numerical approach to semi-classical D-bar problems for real analytic rapidly decreasing potentials. We treat the D-bar problem as a complex linear second order integral equation which is solved with discrete Fourier transforms complemented by a regularization of the singular parts by explicit analytic computation. The resulting algebraic equation is solved either by fixed point iterations or GMRES. Several examples for small values of the semi-classical parameter in the system are discussed.
- Published
- 2018
- Full Text
- View/download PDF
41. Numerical scattering for the defocusing Davey-Stewartson II equation for initial data with compact support
- Author
-
Klein, C. and Stoilov, N.
- Subjects
Mathematics - Numerical Analysis ,Nonlinear Sciences - Exactly Solvable and Integrable Systems - Abstract
In this work we present spectral algorithms for the numerical scattering for the defocusing Davey-Stewartson (DS) II equation with initial data having compact support on a disk, i.e., for the solution of d-bar problems. Our algorithms use polar coordinates and implement a Chebychev spectral scheme for the radial dependence and a Fourier spectral method for the azimuthal dependence. The focus is placed on the construction of complex geometric optics (CGO) solutions which are needed in the scattering approach for DS. We discuss two different approaches: The first constructs a fundamental solution to the d-bar system and applies the CGO conditions on the latter. This is especially efficient for small values of the modulus of the spectral parameter $k$. The second approach uses a fixed point iteration on a reformulated d-bar system containing the spectral parameter explicitly, a price paid to have simpler asymptotics. The approaches are illustrated for the example of the characteristic function of the disk and are shown to exhibit spectral convergence, i.e., an exponential decay of the numerical error with the number of collocation points. An asymptotic formula for large $|k|$ is given for the reflection coefficient., Comment: Introduction change, various minor updates
- Published
- 2018
- Full Text
- View/download PDF
42. FAMU: study of the energy dependent transfer rate $\Lambda_{\mu p \rightarrow \mu O}$
- Author
-
FAMU Collaboration, Mocchiutti, E., Bonvicini, V., Danailov, M., Furlanetto, E., Gadedjisso-Tossou, K. S., Guffanti, D., Pizzolotto, C., Rachevski, A., Stoychev, L., Vallazza, E., Zampa, G., Niemela, J., Ishida, K., Adamczak, A., Baccolo, G., Benocci, R., Bertoni, R., Bonesini, M., Chignoli, F., Clemenza, M., Curioni, A., Maggi, V., Mazza, R., Moretti, M., Nastasi, M., Previtali, E., Bakalov, D., Danev, P., Stoilov, M., Baldazzi, G., Campana, R., D'Antone, I., Furini, M., Fuschino, F., Labanti, C., Margotti, A., Meneghini, S., Morgante, G., Rignanese, L. P., Rossi, P. L., Zuffa, M., Cervi, T., De Bari, A., Menegolli, A., De Vecchi, C., Nardò, R., Rossella, M., Tomaselli, A., Colace, L., De Vincenzi, M., Iaciofano, A., Somma, F., Tortora, L., Ramponi, R., and Vacchi, A.
- Subjects
Nuclear Experiment ,Physics - Data Analysis, Statistics and Probability ,Physics - Instrumentation and Detectors - Abstract
The main goal of the FAMU experiment is the measurement of the hyperfine splitting (hfs) in the 1S state of muonic hydrogen $\Delta E_{hfs}(\mu^-p)1S$. The physical process behind this experiment is the following: $\mu p$ are formed in a mixture of hydrogen and a higher-Z gas. When absorbing a photon at resonance-energy $\Delta E_{hfs}\approx0.182$~eV, in subsequent collisions with the surrounding $H_2$ molecules, the $\mu p$ is quickly de-excited and accelerated by $\sim2/3$ of the excitation energy. The observable is the time distribution of the K-lines X-rays emitted from the $\mu Z$ formed by muon transfer $(\mu p) +Z \rightarrow (\mu Z)^*+p$, a reaction whose rate depends on the $\mu p$ kinetic energy. The maximal response, to the tuned laser wavelength, of the time distribution of X-ray from K-lines of the $(\mu Z)^*$ cascade indicate the resonance. During the preparatory phase of the FAMU experiment, several measurements have been performed both to validate the methodology and to prepare the best configuration of target and detectors for the spectroscopic measurement. We present here the crucial study of the energy dependence of the transfer rate from muonic hydrogen to oxygen ($\Lambda_{\mu p \rightarrow \mu O}$), precisely measured for the first time., Comment: 11 pages, 4 figures, published on Journal of Physics: Conference Series, proc. of International Conference on Precision Physics of Simple Atomic Systems - PSAS2018. arXiv admin note: text overlap with arXiv:1708.03172
- Published
- 2018
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43. Numerical Approach to Painlev\'e Transcendents on Unbounded Domains
- Author
-
Klein, Christian and Stoilov, Nikola
- Subjects
Mathematics - Classical Analysis and ODEs ,Mathematical Physics ,Mathematics - Numerical Analysis - Abstract
A multidomain spectral approach for Painlev\'e transcendents on unbounded domains is presented. This method is designed to study solutions determined uniquely by a, possibly divergent, asymptotic series valid near infinity in a sector and approximates the solution on straight lines lying entirely within said sector without the need of evaluating truncations of the series at any finite point. The accuracy of the method is illustrated for the example of the tritronqu\'ee solution to the Painlev\'e I equation.
- Published
- 2018
- Full Text
- View/download PDF
44. Cosmological Solutions from a Multi-Measure Model with Inflaton Field
- Author
-
Staicova, Denitsa and Stoilov, Michail
- Subjects
General Relativity and Quantum Cosmology ,High Energy Physics - Theory ,83Fxx - Abstract
In a recent work, we demonstrated that a modified gravity model in which a scalar "darkon" field is coupled to both the standard Riemannian metric and to another non-Riemannian volume form is compatible with observational data from Supernovae Type Ia. Here, we investigate a more complicated model with an additional "inflaton" scalar field. We demonstrate numerically that the model can qualitatively reproduce the Universe inflation epoch, matter dominated epoch, and present accelerating expansion in a seamless way. We show that such solutions occur only when the model parameters are within a very particular range. The main numerical problem we are faced with is reproducing the extremely small time of the inflation epoch. Here, we present how the variation of some parameters affects this time., Comment: 11 pages, 4 figures, new figures and comments added. Final version published in Symmetry
- Published
- 2018
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- View/download PDF
45. Cosmological solutions from models with unified dark energy and dark matter and with inflaton field
- Author
-
Staicova, Denitsa and Stoilov, Michail
- Subjects
General Relativity and Quantum Cosmology ,High Energy Physics - Theory ,83Fxx - Abstract
Recently, few cosmological models with additional non-Riemannian volume form(s) have been proposed. In this article we use Supernovae type Ia experimental data to test one of these models which provides a unified description of both dark energy via dynamically generated cosmological constant and dark matter as a "dust" fluid due to a hidden nonlinear Noether symmetry. It turns out that the model allows various scenarios of the future Universe evolution and in the same time perfectly fits contemporary observational data. Further, we investigate the influence of an additional inflaton field with a step like potential. With its help we can reproduce the Universe inflation epoch, matter dominated epoch and present accelerating expansion in a seamless way. Interesting feature is that inflaton undergoes a finite change during its evolution. It can be speculated that the inflaton asymptotic value is connected to the vacuum expectation value of the Higgs field., Comment: 10 pages, 4 figures, prepared for the Proceedings of the XII. International Workshop Lie Theory And Its Applications In Physics (2017)
- Published
- 2018
- Full Text
- View/download PDF
46. The Musashi proteins direct post-transcriptional control of protein expression and alternate exon splicing in vertebrate photoreceptors
- Author
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Fatimah Matalkah, Bohye Jeong, Macie Sheridan, Eric Horstick, Visvanathan Ramamurthy, and Peter Stoilov
- Subjects
Biology (General) ,QH301-705.5 - Abstract
The RNA-binding proteins, Musashi 1 and 2, regulate splicing of photoreceptor-specific alternative exons and activate protein expression, and are essential for promoting translation of proteins required for vision and photoreceptor survival.
- Published
- 2022
- Full Text
- View/download PDF
47. Food Safety Management System (FSMS) Model with Application of the PDCA Cycle and Risk Assessment as Requirements of the ISO 22000:2018 Standard
- Author
-
Antoaneta Stoyanova, Velichka Marinova, Daniel Stoilov, and Damyan Kirechev
- Subjects
food safety ,management systems ,PDCA cycle ,ISO 22000:2018 ,Mathematics ,QA1-939 ,Applied mathematics. Quantitative methods ,T57-57.97 - Abstract
The management strategy requires a shift to change-oriented management. These management approaches are process- and activity-oriented and are based on the assumption that the future is difficult to predict and ineffective for modeling. The aim of this study is to present a model of food safety management using a process approach based on the PDCA cycle set in the international standard ISO 22000:2018 by supplementing the regulatory requirements for food safety management. After analyzing the aspects of food safety management, a model is proposed for risk analysis and assessment at the operational and organisational level. In this study, the FMEA method for risk assessment of storage of foods of plant origin was used. The research can be useful for producers and traders in the planning and development of food safety management systems according to the requirements of the ISO 22000:2018 standard. The implementation of documented rules for compliance with the requirements of the international standard is aimed at the management and control of processes at the operational and organisational level in the activities of companies. Process management and data analysis is a direction to improve activities aimed at minimizing food safety risks.
- Published
- 2022
- Full Text
- View/download PDF
48. Toward the measurement of the hyperfine structure of muonic hydrogen in the FAMU experiment. Multi-pass cavity optimization for experiments with pulsed sources
- Author
-
Bakalov, Dimitar and Stoilov, Mihail
- Subjects
Physics - Atomic Physics - Abstract
We consider a simplified model of the optical multi-pass cavity that is being currently developed by the FAMU collaboration for the measurement of the hyperfine splitting in the ground state of muonic hydrogen and of the Zemach radius of the proton. The model is focused on the time distribution of the events of laser-stimulated hyperfine transitions in the muonuc atom and may be helpful in the preliminary design of the FAMU experimental set-up and, more generally, in the optimization of multi-pass optical cavities for experiments with pulsed lasers., Comment: Talk at the EXA-2017 Conference, Vienna, 2017
- Published
- 2017
- Full Text
- View/download PDF
49. Numerical study of blow-up mechanisms for Davey-Stewartson II systems
- Author
-
Klein, C. and Stoilov, N.
- Subjects
Mathematics - Analysis of PDEs ,Mathematical Physics ,Nonlinear Sciences - Exactly Solvable and Integrable Systems - Abstract
We present a detailed numerical study of various blow-up issues in the context of the focusing Davey-Stewartson II equation. To this end we study Gaussian initial data and perturbations of the lump and the explicit blow-up solution due to Ozawa. Based on the numerical results it is conjectured that the blow-up in all cases is self similar, and that the time dependent scaling is as in the Ozawa solution and not as in the stable blow-up of standard $L^{2}$ critical nonlinear Schr\"odinger equations. The blow-up profile is given by a dynamically rescaled lump.
- Published
- 2017
50. Tests for the extraction of Boer-Mulders functions
- Author
-
Christova, Ekaterina, Leader, Elliot, and Stoilov, Michail
- Subjects
High Energy Physics - Phenomenology - Abstract
At present, the Boer-Mulders (BM) functions are extracted from asymmetry data using the simplifying assumption of their proportionality to the Sivers functions for each quark flavour. Here we present two independent tests for this assumption. We subject COMPASS data on semi-inclusive deep inelastic scattering on the $\langle\cos\phi_h\rangle$, $\langle\cos 2\phi_h\rangle$ and Sivers asymmetries to these tests. Our analysis shows that the tests are satisfied with the available data if the proportionality constant is the same for all quark flavours, which does not correspond to the flavour dependence used in existing analyses. This suggests that the published information on the BM functions may be unreliable. The $\langle\cos\phi_h\rangle$ and $\langle\cos 2 \phi_h\rangle$ asymmetries receive contributions also from the, in principle, calculable Cahn effect. We succeed in extracting the Cahn contributions from experiment (we believe for the first time) and compare with their calculated values, with interesting implications., Comment: 6 pages , a talk presented at the XVII workshop DSPIN-17 in JINR-Dubna, Russia
- Published
- 2017
- Full Text
- View/download PDF
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