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Your search keyword '"Stolker, Joost J."' showing total 22 results
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22 results on '"Stolker, Joost J."'

2. Effects of multivitamin, mineral and n-3 polyunsaturated fatty acid supplementation on aggression among long-stay psychiatric in-patients : Randomised clinical trial

Author

De Bles, Nienke J., Rius-Ottenheim, Nathaly, Geleijnse, Johanna M., Van De Rest, Ondine, Bogers, Jan P.A.M., Schat, Anke, Nijman, Henk L.I., Van Den Berg, David, Joos, Lucas, Van Strater, Annelies, De Ridder, Tine, Stolker, Joost J., Van Den Hout, Wilbert B., Van Hemert, Albert M., Giltay, Erik J., De Bles, Nienke J., Rius-Ottenheim, Nathaly, Geleijnse, Johanna M., Van De Rest, Ondine, Bogers, Jan P.A.M., Schat, Anke, Nijman, Henk L.I., Van Den Berg, David, Joos, Lucas, Van Strater, Annelies, De Ridder, Tine, Stolker, Joost J., Van Den Hout, Wilbert B., Van Hemert, Albert M., and Giltay, Erik J.

Abstract

Background Aggression and violent incidents are a major concern in psychiatric in-patient care. Nutritional supplementation has been found to reduce aggressive incidents and rule violations in forensic populations and children with behavioural problems. Aims To assess whether multivitamin, mineral and n-3 polyunsaturated fatty acid supplementation would reduce the number of aggressive incidents among long-stay psychiatric in-patients. Method The trial was a pragmatic, multicentre, randomised, double-blind placebo-controlled study. Data were collected from 25 July 2016 to 29 October 2019, at eight local sites for mental healthcare in The Netherlands and Belgium. Participants were randomised (1:1) to receive 6-month treatment with either three supplements containing multivitamins, minerals and n-3 polyunsaturated fatty acid, or placebo. The primary outcome was the number of aggressive incidents, determined by the Staff Observation Aggression Scale - Revised (SOAS-R). Secondary outcomes were patient quality of life, affective symptoms and adverse events. Results In total, 176 participants were randomised (supplements, n = 87; placebo, n = 89). Participants were on average 49.3 years old (s.d. 14.5) and 64.2% were male. Most patients had a psychotic disorder (60.8%). The primary outcome of SOAS-R incidents was similar in supplement (1.03 incidents per month, 95% CI 0.74-1.37) and placebo groups (0.90 incidents per month, 95% CI 0.65-1.19), with a rate ratio of 1.08 (95% CI 0.67-1.74, P = 0.75). Differential effects were not found in sensitivity analyses on the SOAS-R or on secondary outcomes. Conclusions Six months of nutritional supplementation did not reduce aggressive incidents among long-stay psychiatric in-patients.

Published
2022

3. Effects of multivitamin, mineral and n-3 polyunsaturated fatty acid supplementation on aggression among long-stay psychiatric in-patients: randomised clinical trial

Author

de Bles, Nienke J., primary, Rius-Ottenheim, Nathaly, additional, Geleijnse, Johanna M., additional, van de Rest, Ondine, additional, Bogers, Jan P.A.M., additional, Schat, Anke, additional, Nijman, Henk L.I., additional, van den Berg, David, additional, Joos, Lucas, additional, van Strater, Annelies, additional, de Ridder, Tine, additional, Stolker, Joost J., additional, van den Hout, Wilbert B., additional, van Hemert, Albert M., additional, and Giltay, Erik J., additional

Published
2022
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22. ECT in Mental Retardation A Review

Author

Waarde, Jeroen A. van, Stolker, Joost J., and Mast, Rose C. van der

Abstract

The use of electroconvulsive therapy (ECT) in patients with mental retardation and a psychiatric disorder seems to be infrequent, and controlled studies are not available. We reviewed the literature on the use of ECT in mental retardation, using Medline, Embase, and the Cochrane Library. References were checked and ECT experts consulted. The reported case studies were examined on patients' characteristics and illness, treatment, and outcome variables. Forty-four patients, mostly with a diagnosis of psychotic depression, were found. In 84 (n 37) of them, ECT was effective and without important side effects. However, relapse occurred frequently, in 48 (n 21) of the patients. In 16 (n 7), side effects and/or no improvement were noted. The reported case studies suggest that ECT may be of value in treating severe psychiatric disorders in mentally retarded patients, with similar indications as in general psychiatry. However, the lack of strong scientific evidence, besides complicated psychiatric assessment as well as ethical and legal issues, probably cause an unnecessarily limited use of ECT in these patients. Further controlled trails are needed to firmly establish the efficacy and safety of ECT in mental retardation.

Published
2001

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