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3. Digitale Patientenreise

Author

Notohamiprodjo, Mike, primary, Behrend, Dirk, additional, Stork, Alexander, additional, Remplik, Philipp, additional, and Elgeti, Florian, additional

Published
2023
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6. Segmentation of Medical Images with a Shape and Motion Model: A Bayesian Perspective

Author

Sénégas, Julien, Netsch, Thomas, Cocosco, Chris A., Lund, Gunnar, Stork, Alexander, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Dough, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Sonka, Milan, editor, Kakadiaris, Ioannis A., editor, and Kybic, Jan, editor

Published
2004
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30. Comparison of the Detection Rate of Simulated Microcalcifications in Full-Field Digital Mammography, Digital Breast Tomosynthesis, and Synthetically Reconstructed 2-Dimensional Images Performed With 2 Different Digital X-ray Mammography Systems

Author

Peters, Sabine, primary, Hellmich, Martin, additional, Stork, Alexander, additional, Kemper, Jörn, additional, Grinstein, Olga, additional, Püsken, Michael, additional, Stahlhut, Leandra, additional, Kinner, Sonja, additional, Maintz, David, additional, and Krug, Kathrin Barbara, additional

Published
2017
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31. Comparison of the Detection Rate of Simulated Microcalcifications in Full-Field Digital Mammography, Digital Breast Tomosynthesis, and Synthetically Reconstructed 2-Dimensional Images Performed With 2 Different Digital X-ray Mammography Systems

Author

Peters, Sabine, Hellmich, Martin, Stork, Alexander, Kemper, Joern, Grinstein, Olga, Puesken, Michael, Stahlhut, Leandra, Kinner, Sonja, Maintz, David, Krug, Kathrin Barbara, Peters, Sabine, Hellmich, Martin, Stork, Alexander, Kemper, Joern, Grinstein, Olga, Puesken, Michael, Stahlhut, Leandra, Kinner, Sonja, Maintz, David, and Krug, Kathrin Barbara

Abstract

Objective: The aim of this study was to compare the microcalcification detectability in an anthropomorphic phantom model regarding number, size, and shape in full-field digitalmammography (FFDM), synthetically reconstructed 2-dimensional (Synthetic-2D) images, and digital breast tomosynthesis (DBT) performed with 2 different x-ray mammography systems. Materials and Methods: Simulated microcalcifications of different numbers (0 to > 39), sizes (diameter, 100-800 mu m), and shapes (round vs heterogeneous) were scattered by random distribution on 50 film phantoms each divided in 4 quadrants. The FFDM and DBT x-rays were taken from each of these 50 films with both x-ray mammography systems (SenoClaire; GE Healthcare, Selenia Dimensions, Hologic) using an anthropomorphic scattering body and automatic exposure control. The resulting exposure factors were similar to a clinical setting. The synthetically reconstructed 2D images were generated automatically on both systems. All FFDM, Synthetic-2D, and DBT images were interpreted in randomized order and independently of each other by 6 radiologists using a structured questionnaire. Results: The number categories of simulated microcalcifications were correctly evaluated in 55.3% of instances (quadrant by reader) in FFDM, 50.9% in the Synthetic-2D views, and 59.5% in DBT, summarized for 200 quadrants per reader for each Device A and B, respectively. Full-field digital mammography was superior to Synthetic-2D (mean difference, 4%; 95% confidence interval [ CI], 2%-7%; P < 0.001), and DBT was superior to both FFDM (mean difference, 4%; 95% CI, 2%-7%; P = 0.002) and Synthetic-2D (mean difference, 9%; 95% CI, 6%-11%; P < 0.001). This trend was consistent in all subgroup analyses. The number of the smallest microcalcifications (100-399 mu m) was correctly evaluated in 25.2% of the FFDM, in 14.2% for Synthetic-2D, and in 28.3% of the DBT images. Underestimations of the number of simulated microcalcifications were more common than ove

Published
2017

32. Reducing CT radiation dose with iterative reconstruction algorithms: the influence of scan and reconstruction parameters on image quality and CTDIvol

Author

Adam, Gerhard, Heverhagen, Johannes, Klink, Thorsten, Begemann, Philipp, Stork, Alexander, and Obmann, Verena Carola

Subjects
610 Medicine & health
Abstract

OBJECTIVES In this phantom CT study, we investigated whether images reconstructed using filtered back projection (FBP) and iterative reconstruction (IR) with reduced tube voltage and current have equivalent quality. We evaluated the effects of different acquisition and reconstruction parameter settings on image quality and radiation doses. Additionally, patient CT studies were evaluated to confirm our phantom results. METHODS Helical and axial 256 multi-slice computed tomography scans of the phantom (Catphan(®)) were performed with varying tube voltages (80-140kV) and currents (30-200mAs). 198 phantom data sets were reconstructed applying FBP and IR with increasing iterations, and soft and sharp kernels. Further, 25 chest and abdomen CT scans, performed with high and low exposure per patient, were reconstructed with IR and FBP. Two independent observers evaluated image quality and radiation doses of both phantom and patient scans. RESULTS In phantom scans, noise reduction was significantly improved using IR with increasing iterations, independent from tissue, scan-mode, tube-voltage, current, and kernel. IR did not affect high-contrast resolution. Low-contrast resolution was also not negatively affected, but improved in scans with doses

Published
2014
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33. The Effect of Moderate Hypoglycemia on Driving Performance of Type 1 Diabetic Subjects

Author

STORK, ALEXANDER D. M., SELS, JAN-WILLEM E. M., JANSSEN, WIEL H., MARTENS, MARIEKE H., ERKELENS, D. WILLEM, and VENEMAN, THIEMO F.

Subjects
Physiological aspects, Complications and side effects, Health aspects, Motor vehicle drivers -- Health aspects -- Physiological aspects, Type 1 diabetes -- Complications and side effects, Diabetics -- Health aspects -- Physiological aspects, Hypoglycemia -- Physiological aspects -- Complications and side effects, Automobile drivers -- Health aspects -- Physiological aspects
Abstract

The influence of type 1 diabetes mellitus on driving behaviour and the occurrence of traffic incidents remains controversial. However, throughout the world restrictive legislature concerning professional insulin-using diabetic drivers has [...]

Published
2000

36. Prediction of Left Ventricular Remodeling and Analysis of Infarct Resorption in Patients with Reperfused Myocardial Infarcts by Using Contrast-enhanced MR Imaging

Author

Lund, Gunnar K., primary, Stork, Alexander, additional, Muellerleile, Kai, additional, Barmeyer, Achim A., additional, Bansmann, Martin P., additional, Knefel, Meike, additional, Schlichting, Ulrike, additional, Müller, Martin, additional, Verde, Pablo E., additional, Adam, Gerhard, additional, Meinertz, Thomas, additional, and Saeed, Maythem, additional

Published
2007
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45. Development of a Cardiac Neocavity After Mechanic Double-Valve Replacement

Author

Barmeyer, Achim, primary, Muellerleile, Kai, additional, Lund, Gunnar K., additional, Stork, Alexander, additional, Gosau, Nils, additional, Koops, Andreas, additional, Gehrmann, Sebastian, additional, Hofmann, Thomas, additional, Koschyk, Ditmar H., additional, Nolte-Ernsting, Claus, additional, Adam, Gerhard, additional, and Meinertz, Thomas, additional

Published
2005
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48. Clinical Relevance of Calcaneal Bone Cysts

Author

Pogoda, Pia, primary, Priemel, Matthias, additional, Linhart, Wolfgang, additional, Stork, Alexander, additional, Adam, Gerhard, additional, Windolf, Joachim, additional, Rueger, Johannes M, additional, and Amling, Michael, additional

Published
2004
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