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27 results on '"Strandberg, Marjatta"'

5. Cardiac remodeling in a new pig model of chronic heart failure: Assessment of left ventricular functional, metabolic, and structural changes using PET, CT, and echocardiography

Author

Tarkia, Miikka, Stark, Christoffer, Haavisto, Matti, Kentala, Rasmus, Vähäsilta, Tommi, Savunen, Timo, Strandberg, Marjatta, Hynninen, Ville-Veikko, Saunavaara, Virva, Tolvanen, Tuula, Teräs, Mika, Rokka, Johanna, Pietilä, Mikko, Saukko, Pekka, Roivainen, Anne, Saraste, Antti, and Knuuti, Juhani

Published
2015
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13. Evaluation of a New Skeletal Troponin I Assay in Patients with Idiopathic Inflammatory Myopathies

Author

Bamberg, Katriina, primary, Mehtälä, Laura, primary, Arola, Olli, primary, Laitinen, Seppo, primary, Nordling, Pauliina, primary, Strandberg, Marjatta, primary, Strandberg, Niko, primary, Paltta, Johanna, primary, Mali, Markku, primary, Espinosa-Ortega, Fabricio, primary, Pirilä, Laura, primary, Lundberg, Ingrid E, primary, Savukoski, Tanja, primary, and Pettersson, Kim, primary

Published
2020
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14. THU0331 SKELETAL TROPONIN I A POSSIBLE NOVEL BIOMARKER FOR MANAGEMENT OF PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES

Author

Bamberg, Katriina, primary, Mehtälä, Laura, additional, Arola, Olli, additional, Laitinen, Seppo, additional, Nordling, Pauliina, additional, Strandberg, Marjatta, additional, Strandberg, Niko, additional, Paltta, Johanna, additional, Mali, Markku, additional, Espinosa-Ortega, Fabricio, additional, Pirilä, Laura, additional, Lundberg, Ingrid E., additional, Savukoski, Tanja, additional, and Pettersson, Kim, additional

Published
2019
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15. Reversibility of myocardial metabolism and remodelling in morbidly obese patients 6 months after bariatric surgery

Author

Hannukainen, Jarna C., primary, Lautamäki, Riikka, additional, Pärkkä, Jussi, additional, Strandberg, Marjatta, additional, Saunavaara, Virva, additional, Hurme, Saija, additional, Soinio, Minna, additional, Dadson, Prince, additional, Virtanen, Kirsi A., additional, Grönroos, Tove, additional, Forsback, Sarita, additional, Salminen, Paulina, additional, Iozzo, Patricia, additional, and Nuutila, Pirjo, additional

Published
2018
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17. Accuracy of echocardiographic area-length method in chronic myocardial infarction: comparison with cardiac CT in pigs

Author

Ballo, Haitham, Tarkia, Miikka, Haavisto, Matti, Stark, Christoffer, Strandberg, Marjatta, Vähäsilta, Tommi, Saunavaara, Virva, Tolvanen, Tuula, Teräs, Mika, Hynninen, Ville-Veikko, Savunen, Timo, Roivainen, Anne, Knuuti, Juhani, Saraste, Antti, Ballo, Haitham, Tarkia, Miikka, Haavisto, Matti, Stark, Christoffer, Strandberg, Marjatta, Vähäsilta, Tommi, Saunavaara, Virva, Tolvanen, Tuula, Teräs, Mika, Hynninen, Ville-Veikko, Savunen, Timo, Roivainen, Anne, Knuuti, Juhani, and Saraste, Antti

Abstract

Background We evaluated echocardiographic area-length methods to measure left ventricle (LV) volumes and ejection fraction (EF) in parasternal short axis views in comparison with cardiac computed tomography (CT) in pigs with chronic myocardial infarction (MI). Methods Male farm pigs with surgical occlusion of the left anterior descending coronary artery (n = 9) or sham operation (n = 5) had transthoracic echocardiography and cardiac-CT 3 months after surgery. We measured length of the LV in parasternal long axis view, and both systolic and diastolic LV areas in parasternal short axis views at the level of mitral valve, papillary muscles and apex. Volumes and EF of the LV were calculated using Simpson’s method of discs (tri-plane area) or Cylinder-hemiellipsoid method (single plane area). Results The pigs with coronary occlusion had anterior MI scars and reduced EF (average EF 42 ± 10%) by CT. Measurements of LV volumes and EF were reproducible by echocardiography. Compared with CT, end-diastolic volume (EDV) measured by echocardiography showed good correlation and agreement using either Simpson’s method (r = 0.90; mean difference −2, 95% CI −47 to 43 mL) or Cylinder-hemiellipsoid method (r = 0.94; mean difference 3, 95% CI −44 to 49 mL). Furthermore, End-systolic volume (ESV) measured by echocardiography showed also good correlation and agreement using either Simpson’s method (r = 0.94; mean difference 12 ml, 95% CI: −16 to 40) or Cylinder-hemiellipsoid method (r = 0.97; mean difference:13 ml, 95% CI: −8 to 33). EF was underestimated using either Simpson’s method (r = 0.78; mean difference −6, 95% CI −11 to 1%) or Cylinder-hemiellipsoid method (r = 0.74; mean difference −4, 95% CI–10 to 2%). Conclusion Our results indicate that measurement of LV volumes may be accurate, but EF is underestimated using either three or single parasternal short axis planes by echocardiography in a large animal model of chronic MI.

Published
2017

18. Accuracy of echocardiographic area-length method in chronic myocardial infarction: comparison with cardiac CT in pigs

Author

Ballo, Haitham, primary, Tarkia, Miikka, additional, Haavisto, Matti, additional, Stark, Christoffer, additional, Strandberg, Marjatta, additional, Vähäsilta, Tommi, additional, Saunavaara, Virva, additional, Tolvanen, Tuula, additional, Teräs, Mika, additional, Hynninen, Ville-Veikko, additional, Savunen, Timo, additional, Roivainen, Anne, additional, Knuuti, Juhani, additional, and Saraste, Antti, additional

Published
2017
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20. [18F]FDG Accumulation in Early Coronary Atherosclerotic Lesions in Pigs

Author

Tarkia, Miikka, primary, Saraste, Antti, additional, Stark, Christoffer, additional, Vähäsilta, Tommi, additional, Savunen, Timo, additional, Strandberg, Marjatta, additional, Saunavaara, Virva, additional, Tolvanen, Tuula, additional, Teuho, Jarmo, additional, Teräs, Mika, additional, Metsälä, Olli, additional, Rinne, Petteri, additional, Heinonen, Ilkka, additional, Savisto, Nina, additional, Pietilä, Mikko, additional, Saukko, Pekka, additional, Roivainen, Anne, additional, and Knuuti, Juhani, additional

Published
2015
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21. Abstract 15108: Imaging Coronary Atherosclerosis Using [18F]FDG PET-CT: Validation Study in Pigs

Author

Tarkia, Miikka, primary, Saraste, Antti, additional, Stark, Christoffer, additional, Vähäsilta, Tommi, additional, Savunen, Timo, additional, Strandberg, Marjatta, additional, Saunavaara, Virva, additional, Tolvanen, Tuula, additional, Teuho, Jarmo, additional, Teräs, Mika, additional, Metsälä, Olli, additional, Rinne, Petteri, additional, Heinonen, Ilkka, additional, Sarja, Nina, additional, Pietilä, Mikko, additional, Saukko, Pekka, additional, Roivainen, Anne, additional, and Knuuti, Juhani, additional

Published
2014
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23. Abstract 19598: Evaluation of Left Ventricle Function and Oxidative Metabolism in Large Animal Model of Chronic Heart Failure

Author

Tarkia, Miikka, primary, Haavisto, Matti, additional, Stark, Christoffer, additional, Vähäsilta, Tommi, additional, Savunen, Timo, additional, Strandberg, Marjatta, additional, Lepomäki, Virva, additional, Pietilä, Mikko, additional, Saukko, Pekka, additional, Roivainen, Anne, additional, Saraste, Antti, additional, and Knuuti, Juhani, additional

Published
2012
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24. [18F]FDG Accumulation in Early Coronary Atherosclerotic Lesions in Pigs.

Author

Tarkia, Miikka, Saraste, Antti, Stark, Christoffer, Vähäsilta, Tommi, Savunen, Timo, Strandberg, Marjatta, Saunavaara, Virva, Tolvanen, Tuula, Teuho, Jarmo, Teräs, Mika, Metsälä, Olli, Rinne, Petteri, Heinonen, Ilkka, Savisto, Nina, Pietilä, Mikko, Saukko, Pekka, Roivainen, Anne, and Knuuti, Juhani

Subjects
BIOACCUMULATION, CORONARY disease, ATHEROSCLEROSIS, DISEASE progression, INFLAMMATION, LABORATORY swine
Abstract

Objective: Inflammation is an important contributor to atherosclerosis progression. A glucose analogue 18F-fluorodeoxyglucose ([18F]FDG) has been used to detect atherosclerotic inflammation. However, it is not known to what extent [18F]FDG is taken up in different stages of atherosclerosis. We aimed to study the uptake of [18F]FDG to various stages of coronary plaques in a pig model. Methods: First, diabetes was caused by streptozotocin injections (50 mg/kg for 3 days) in farm pigs (n = 10). After 6 months on high-fat diet, pigs underwent dual-gated cardiac PET/CT to measure [18F]FDG uptake in coronary arteries. Coronary segments (n = 33) were harvested for ex vivo measurement of radioactivity and autoradiography (ARG). Results: Intimal thickening was observed in 16 segments and atheroma type plaques in 10 segments. Compared with the normal vessel wall, ARG showed 1.7±0.7 times higher [18F]FDG accumulation in the intimal thickening and 4.1±2.3 times higher in the atheromas (P = 0.004 and P = 0.003, respectively). Ex vivo mean vessel-to-blood ratio was higher in segments with atheroma than those without atherosclerosis (2.6±1.2 vs. 1.3±0.7, P = 0.04). In vivo PET imaging showed the highest target-to-background ratio (TBR) of 2.7. However, maximum TBR was not significantly different in segments without atherosclerosis (1.1±0.5) and either intimal thickening (1.2±0.4, P = 1.0) or atheroma (1.6±0.6, P = 0.4). Conclusions: We found increased uptake of [18F]FDG in coronary atherosclerotic lesions in a pig model. However, uptake in these early stage lesions was not detectable with in vivo PET imaging. Further studies are needed to clarify whether visible [18F]FDG uptake in coronary arteries represents more advanced, highly inflamed plaques. [ABSTRACT FROM AUTHOR]

Published
2015
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26. Etiology, diagnostics and treatment of cardiogenic stroke.

Author

Strandberg M, Mustonen P, Taina M, Korpela J, Vanninen S, and Hedman M

Subjects
Anticoagulants therapeutic use, Echocardiography, Transesophageal, Humans, Heart Diseases complications, Stroke diagnosis, Stroke etiology, Stroke therapy
Abstract

Approximately 15 to 40% of cerebral infarctions and transient ischemic attacks (TIA) are of cardiac origin. Knowledge of a significant cardiac disease arouses the suspicion of cardiogenic embolism, but its diagnosis requires identification of the source of embolism. Atrial fibrillation is the most common cause of cardiogenic embolism, and should be actively sought after an ischemic cerebrovascular attact. The detection of atrial fibrillation or an intracardiac thrombus in these patients requires initiation of permanent anticoagulant therapy. Transesophageal echocardiography (TEE) has proven to be more sensitive than transthoracic echocardiography (TTE) in detecting certain possible cardiogenic sources of embolism.

Published
2016

27. [Transesophageal echocardiography-guided cardioversion].

Author

Saarela E, Koskela V, Strandberg M, Airaksinen KE, Niemelä M, and Raatikainen MJ

Subjects
Adult, Aged, Aged, 80 and over, Atrial Fibrillation mortality, Cohort Studies, Drug Administration Schedule, Female, Humans, Male, Middle Aged, Prognosis, Retrospective Studies, Risk Assessment, Severity of Illness Index, Survival Rate, Treatment Outcome, Anticoagulants therapeutic use, Atrial Fibrillation diagnostic imaging, Atrial Fibrillation therapy, Echocardiography, Transesophageal methods, Electric Countershock methods
Published
2004

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