Search

Your search keyword '"Strobert, Elizabeth A."' showing total 137 results
Start Over Author "Strobert, Elizabeth A."
137 results on '"Strobert, Elizabeth A."'

3. CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates

Author

Watkins, Benjamin K., Tkachev, Victor, Furlan, Scott N., Hunt, Daniel J., Betz, Kayla, Yu, Alison, Brown, Melanie, Poirier, Nicolas, Zheng, Hengqi Betty, Taraseviciute, Agne, Colonna, Lucrezia, Mary, Caroline, Blancho, Gilles, Soulillou, Jean-Paul, Panoskaltsis- Mortari, Angela, Sharma, Prachi, Garcia, Anapatricia, Strobert, Elizabeth, Hamby, Kelly, Garret, Aneesah, Deane, Taylor, Blazar, Bruce R., Vanhove, Bernard, and Kean, Leslie S.

Subjects
Care and treatment, Physiological aspects, Models, Health aspects, Graft vs. host disease -- Care and treatment -- Models, Immune response -- Health aspects, Membrane proteins -- Physiological aspects -- Health aspects, T cells -- Physiological aspects -- Health aspects
Abstract

Introduction Graft-versus-host disease (GVHD) represents a major cause of mortality after hematopoietic stem cell transplant (HCT) (1-4), and despite substantial effort, the control of GVHD remains one of the key [...], Controlling graft-versus-host disease (GVHD) remains a major unmet need in stem cell transplantation, and new, targeted therapies are being actively developed. CD28-CD80/86 costimulation blockade represents a promising strategy, but targeting CD80/CD86 with CTLA4-Ig may be associated with undesired blockade of coinhibitory pathways. In contrast, targeted blockade of CD28 exclusively inhibits T cell costimulation and may more potently prevent GVHD. Here, we investigated FR104, an antagonistic CD28-specific pegylated-Fab', in the nonhuman primate (NHP) GVHD model and completed a multiparameter interrogation comparing it with CTLA4-Ig, with and without sirolimus, including clinical, histopathologic, flow cytometric, and transcriptomic analyses. We document that FR104 monoprophylaxis and combined prophylaxis with FR104/sirolimus led to enhanced control of effector T cell proliferation and activation compared with the use of CTLA4-Ig or CTLA4- Ig/sirolimus. Importantly, FR104/sirolimus did not lead to a beneficial impact on Treg reconstitution or homeostasis, consistent with control of conventional T cell activation and IL-2 production needed to support Tregs. While FR104/sirolimus had a salutary effect on GVHD-free survival, overall survival was not improved, due to death in the absence of GVHD in several FR104/ sirolimus recipients in the setting of sepsis and a paralyzed INF-[gamma] response. These results therefore suggest that effectively deploying CD28 in the clinic will require close scrutiny of both the benefits and risks of extensively abrogating conventional T cell activation after transplant.

Published
2018
Full Text
View/download PDF

5. Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques

Author

Magnani, Diogo M., Rogers, Thomas F., Beutler, Nathan, Ricciardi, Michael J., Bailey, Varian K., Gonzalez-Nieto, Lucas, Briney, Bryan, Sok, Devin, Le, Khoa, Strubel, Alexander, Gutman, Martin J., Pedreño-Lopez, Núria, Grubaugh, Nathan D., Silveira, Cassia G. T., Maxwell, Helen S., Domingues, Aline, Martins, Mauricio A., Lee, David E., Okwuazi, Erica E., Jean, Sherrie, Strobert, Elizabeth A., Chahroudi, Ann, Silvestri, Guido, Vanderford, Thomas H., Kallas, Esper G., Desrosiers, Ronald C., Bonaldo, Myrna C., Whitehead, Stephen S., Burton, Dennis R., and Watkins, David I.

Published
2017
Full Text
View/download PDF

7. Relative Transmissibility of an R5 Clade C Simian-Human Immunodeficiency Virus Across Different Mucosae in Macaques Parallels the Relative Risks of Sexual HIV-1 Transmission in Humans via Different Routes

Author

Chenine, Agnès L., Siddappa, Nagadenahalli B., Kramer, Victor G., Sciaranghella, Gaia, Rasmussen, Robert A., Lee, Sandra J., Santosuosso, Michael, Poznansky, Mark C., Velu, Vijayakumar, Amara, Rama R., Souder, Chris, Anderson, Daniel C., Villinger, François, Else, James G., Novembre, Francis J., Strobert, Elizabeth, O'Neil, Shawn P., Secor, W. Evan, and Ruprecht, Ruth M.

Published
2010

9. GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28− CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression

Author

Miller, Weston P., Srinivasan, Swetha, Panoskaltsis-Mortari, Angela, Singh, Karnail, Sen, Sharon, Hamby, Kelly, Deane, Taylor, Stempora, Linda, Beus, Jonathan, Turner, Alexa, Wheeler, Caleb, Anderson, Daniel C., Sharma, Prachi, Garcia, Anapatricia, Strobert, Elizabeth, Elder, Eric, Crocker, Ian, Crenshaw, Timothy, Penedo, M. Cecilia T., Ward, Thea, Song, Mingqing, Horan, John, Larsen, Christian P., Blazar, Bruce R., and Kean, Leslie S.

Published
2010
Full Text
View/download PDF

12. LFA-1--specific therapy prolongs allograft survival in rhesus macaques

Author

Badell, Idelberto R., Russell, Maria C., Thompson, Peter W., Turner, Alexandra P., Weaver, Tim A., Robertson, Jennifer M., Avila, Jose G., Cano, Jose A., Johnson, Brandi E., Song, Mingqing, Leopardi, Frank V., Swygert, Sarah, Strobert, Elizabeth A., Ford, Mandy L., Kirk, Allan D., and Larsen, Christian P.

Subjects
Management, Standards, Properties, Methods, Company business management, Homografts -- Management -- Standards, Antigens -- Properties, Immunotherapy -- Methods, Antibodies -- Properties, T cells -- Properties, Viral antibodies -- Properties
Abstract

Introduction T cells play a central role in the initiation of allograft rejection. As a result, immunosuppressive agents that selectively target molecules critical to T cell activation have the potential [...], Outcomes in transplantation have been limited by suboptimal long-term graft survival and toxicities associated with current immunosuppressive approaches. T cell costimulation blockade has shown promise as an alternative strategy to avoid the side effects of conventional immunosuppressive therapies, but targeting CD28-mediated costimulation alone has proven insufficient to prevent graft rejection in primates. Donor-specific memory T ([T.sub.M]) cells have been implicated in costimulation blockade-resistant transplant rejection, due to their enhanced effector function and decreased reliance on costimulatory signaling. Thus, we have tested a potential strategy to overcome [T.sub.M] cell-driven rejection by targeting molecules preferentially expressed on these cells, such as the adhesion molecule lymphocyte function-associated antigen 1 (LFA-1). Here, we show that short-term treatment (i.e., induction therapy) with the LFA-1--specific antibody TS-1/22 in combination with either basiliximab (an IL-2Rα-specific mAb) and sirolimus (a mammalian target of rapamycin inhibitor) or belatacept (a high-affinity variant of the CD28 costimulation-blocker CTLA4Ig) prolonged islet allograft survival in nonhuman primates relative to control treatments. Moreover, TS-1/22 masked LFA-1 on [T.sub.M] cells in vivo and inhibited the generation of alloproliferative and cytokine-producing effector T cells that expressed high levels of LFA-1 in vitro. These results support the use of LFA-1--specific induction therapy to neutralize costimulation blockade-resistant populations of T cells and further evaluation of LFA-1--specific therapeutics for use in transplantation.

Published
2010
Full Text
View/download PDF

13. Pathology of Sooty Mangabeys (Cercocebus atys)

Author

Courtney, Cynthia L., primary, Garcia, Anapatricia, additional, Sharma, Prachi, additional, Anderson, Daniel C., additional, Cohen, Joyce K., additional, Strobert, Elizabeth, additional, Villinger, Francois, additional, and Gumber, Sanjeev, additional

Published
2014
Full Text
View/download PDF

21. Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways

Author

Cardona, Kenneth, Korbutt, Gregory S., Milas, Zvonimir, Lyon, James, Cano, Jose, Jiang, Wanhong, Bello-Laborn, Hameeda, Hacquoil, Brad, Strobert, Elizabeth, Gangappa, Shivaprakash, Weber, Collin J., Pearson, Thomas C., Rajotte, Ray V., and Larsen, Christian P.

Abstract

Author(s): Kenneth Cardona [1, 4]; Gregory S Korbutt [2, 4]; Zvonimir Milas [1]; James Lyon [2]; Jose Cano [1]; Wanhong Jiang [1]; Hameeda Bello-Laborn [1]; Brad Hacquoil [2]; Elizabeth Strobert [...]

Published
2006
Full Text
View/download PDF

22. SHIV-1157i and passaged progeny viruses encoding R5 HIV-1 clade C env cause AIDS in rhesus monkeys

Author

Siddappa Nagadenahalli B, Kramer Victor G, Chenine Agnès L, Sharma Prachi, Ong Helena, Song Ruijiang, Rasmussen Robert A, Humbert Michael, Xu Weidong, Else James G, Novembre Francis J, Strobert Elizabeth, O'Neil Shawn P, and Ruprecht Ruth M

Subjects
Immunologic diseases. Allergy, RC581-607
Abstract

Abstract Background Infection of nonhuman primates with simian immunodeficiency virus (SIV) or chimeric simian-human immunodeficiency virus (SHIV) strains is widely used to study lentiviral pathogenesis, antiviral immunity and the efficacy of AIDS vaccine candidates. SHIV challenges allow assessment of anti-HIV-1 envelope responses in primates. As such, SHIVs should mimic natural HIV-1 infection in humans and, to address the pandemic, encode HIV-1 Env components representing major viral subtypes worldwide. Results We have developed a panel of clade C R5-tropic SHIVs based upon env of a Zambian pediatric isolate of HIV-1 clade C, the world's most prevalent HIV-1 subtype. The parental infectious proviral clone, SHIV-1157i, was rapidly passaged through five rhesus monkeys. After AIDS developed in the first animal at week 123 post-inoculation, infected blood was infused into a sixth monkey. Virus reisolated at this late stage was still exclusively R5 tropic and mucosally transmissible. Here we describe the long-term follow-up of this initial cohort of six monkeys. Two have remained non-progressors, whereas the other four gradually progressed to AIDS within 123–270 weeks post-exposure. Two progressors succumbed to opportunistic infections, including a case of SV40 encephalitis. Conclusion These data document the disease progression induced by the first mucosally transmissible, pathogenic R5 non-clade B SHIV and suggest that SHIV-1157i-derived viruses, including the late-stage, highly replication-competent SHIV-1157ipd3N4 previously described (Song et al., 2006), display biological characteristics that mirror those of HIV-1 clade C and support their expanded use for AIDS vaccine studies in nonhuman primates.

Published
2008
Full Text
View/download PDF

23. Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization

Author

Strobert Elizabeth, Weiss Walter R, Geall Andrew, Patterson Noelle B, Fallarme Victoria, Ganeshan Harini, Abot Steve, Richie Nancy, Banania Glenna, Baraceros Maria F, Moreno Alberto, Charoenvit Yupin, Jiang George, Caro-Aquilar Ivette, Lanar David E, Saul Allan, Martin Laura B, Gowda Kalpana, Morrissette Craig R, Kaslow David C, Carucci Daniel J, Galinski Mary R, and Doolan Denise L

Subjects
Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
Abstract

Abstract The present study has evaluated the immunogenicity of single or multiple Plasmodium falciparum (Pf) antigens administered in a DNA prime/poxvirus boost regimen with or without the poloxamer CRL1005 in rhesus monkeys. Animals were primed with PfCSP plasmid DNA or a mixture of PfCSP, PfSSP2/TRAP, PfLSA1, PfAMA1 and PfMSP1-42 (CSLAM) DNA vaccines in PBS or formulated with CRL1005, and subsequently boosted with ALVAC-Pf7, a canarypox virus expressing the CSLAM antigens. Cell-mediated immune responses were evaluated by IFN-γ ELIspot and intracellular cytokine staining, using recombinant proteins and overlapping synthetic peptides. Antigen-specific and parasite-specific antibody responses were evaluated by ELISA and IFAT, respectively. Immune responses to all components of the multi-antigen mixture were demonstrated following immunization with either DNA/PBS or DNA/CRL1005, and no antigen interference was observed in animals receiving CSLAM as compared to PfCSP alone. These data support the down-selection of the CSLAM antigen combination. CRL1005 formulation had no apparent effect on vaccine-induced T cell or antibody responses, either before or after viral boost. In high responder monkeys, CD4+IL-2+ responses were more predominant than CD8+ T cell responses. Furthermore, CD8+ IFN-γ responses were detected only in the presence of detectable CD4+ T cell responses. Overall, this study demonstrates the potential for multivalent Pf vaccines based on rational antigen selection and combination, and suggests that further formulation development to increase the immunogenicity of DNA encoded antigens is warranted.

Published
2007
Full Text
View/download PDF

26. Heart disease is common in humans and chimpanzees, but is caused by different pathological processes

Author

Varki, Nissi, Anderson, Dan, Herndon, James G, Pham, Tho, Gregg, Christopher J, Cheriyan, Monica, Murphy, James, Strobert, Elizabeth, Fritz, Jo, Else, James G, and Varki, Ajit

Subjects
evolution, heart failure, myocardial fibrosis, Original Articles, great ape, heart attacks, heart disease, atherosclerosis, hominids
Abstract

Heart disease is common in both humans and chimpanzees, manifesting typically as sudden cardiac arrest or progressive heart failure. Surprisingly, although chimpanzees are our closest evolutionary relatives, the major cause of heart disease is different in the two species. Histopathology data of affected chimpanzee hearts from two primate centers, and analysis of literature indicate that sudden death in chimpanzees (and in gorillas and orangutans) is commonly associated with diffuse interstitial myocardial fibrosis of unknown cause. In contrast, most human heart disease results from coronary artery atherosclerosis, which occludes myocardial blood supply, causing ischemic damage. The typical myocardial infarction of humans due to coronary artery thrombosis is rare in these apes, despite their human-like coronary-risk-prone blood lipid profiles. Instead, chimpanzee 'heart attacks' are likely due to arrythmias triggered by myocardial fibrosis. Why do humans not often suffer from the fibrotic heart disease so common in our closest evolutionary cousins? Conversely, why do chimpanzees not have the kind of heart disease so common in humans? The answers could be of value to medical care, as well as to understanding human evolution. A preliminary attempt is made to explore possibilities at the histological level, with a focus on glycosylation changes.

Published
2009

27. Self-Injurious Behavior Secondary to Cytomegalovirus-Induced Neuropathy in an SIV-Infected Rhesus Macaque (Macaca mulatta)

Author

Clemmons, Elizabeth A, Gumber, Sanjeev, Strobert, Elizabeth, Bloomsmith, Mollie A, and Jean, Sherrie M

Subjects
Nonhuman Primate Models, Cytomegalovirus Infections, Simian Acquired Immunodeficiency Syndrome, Animals, Peripheral Nervous System Diseases, Female, Macaca mulatta, Self-Injurious Behavior
Abstract

A 3.5-y-old, female rhesus macaque (Macaca mulatta) inoculated with SIVmac239 presented 8 mo later for inappetence and facial bruising. Physical examination revealed a superficial skin abrasion below the left eye, bruising below the left brow, and epistaxis of the left nostril. There were no significant findings on CBC, serum chemistry, urinalysis, or radiographs. Differential diagnoses included infectious etiologies, self-injurious behavior, immune-mediated dermatitis, and neoplasia. Lack of response to antibiotic and analgesic therapy and observations of the macaque made it apparent that the skin lesions were self-inflicted. The excoriations rapidly progressed to extend over the nose, and the left palpebrae became edematous. Euthanasia was elected because the macaque appeared to be experiencing continued discomfort despite analgesic therapy. Histopathologic examination revealed systemic cytomegalovirus (CMV) infection involving the facial nerves, periocular nerves, meninges, and perimesenteric lymph nodes. CMV is a common infection in macaques, with adult seroprevalence close to 100% in most colonies. Infection in immunocompetent animals is usually asymptomatic but can cause significant clinical disease in immunodeficient hosts. CMV is associated with a painful peripheral neuropathy in human AIDS patients, and analgesic treatment is often unsatisfactory. Peripheral neuropathy secondary to CMV should be considered as an underlying cause of self-injurious behavior in SIV-infected macaques. Macaques affected by other diseases and disorders may also be at risk for development of painful peripheral neuropathies.

Published
2015

31. Immunogenicity of 50-Valent Rhinovirus Vaccine

Author

Lee, Sujin, primary, Nguyen, Minh Trang, additional, Currier, Michael G., additional, Jenkins, Joe B., additional, Strobert, Elizabeth A., additional, Kajon, Adriana E., additional, Madan-Lala, Ranjna, additional, Bochkov, Yury A., additional, Gern, James E., additional, Roy, Krishnendu, additional, Lu, Xiaoyan, additional, Erdman, Dean D., additional, Spearman, Paul, additional, and Moore, Martin L., additional

Published
2017
Full Text
View/download PDF

32. A polyvalent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques

Author

Lee, Sujin, primary, Nguyen, Minh Trang, additional, Currier, Michael G., additional, Jenkins, Joe B., additional, Strobert, Elizabeth A., additional, Kajon, Adriana E., additional, Madan-Lala, Ranjna, additional, Bochkov, Yury A., additional, Gern, James E., additional, Roy, Krishnendu, additional, Lu, Xiaoyan, additional, Erdman, Dean D., additional, Spearman, Paul, additional, and Moore, Martin L., additional

Published
2016
Full Text
View/download PDF

33. 50-valent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques

Author

Lee, Sujin, primary, Nguyen, Minh Trang, additional, Currier, Michael G., additional, Jenkins, Joe B., additional, Strobert, Elizabeth A., additional, Kajon, Adriana E., additional, Madan-Lala, Ranjna, additional, Bochkov, Yury A., additional, Gern, James E., additional, Roy, Krishnendu, additional, Lu, Xiaoyan, additional, Erdman, Dean D., additional, Spearman, Paul, additional, and Moore, Martin L., additional

Published
2016
Full Text
View/download PDF

34. CD8-Predominant T Cell Meningitis Accompanies Gvhd in Primates and Is Prevented with Immunoprophylaxis

Author

Kaliyaperumal, Saravanan, primary, Sharma, Prachi, additional, Watkins, Benjamin K., additional, Furlan, Scott N., additional, Ramakrishnan, Swetha, additional, Giver, Cynthia, additional, Garcia, Anapatricia, additional, Courtney, Cynthia, additional, Hamby, Kelly, additional, Garrett, Aneesah, additional, Deane, Taylor, additional, Strobert, Elizabeth, additional, Jenkins, Joe, additional, Elder, Eric, additional, Eishiavielli, Natia, additional, Crenshaw, Timothy, additional, Blazar, Bruce R., additional, Waller, Edmund K., additional, Westmoreland, Susan, additional, and Kean, Leslie S., additional

Published
2014
Full Text
View/download PDF

36. Synergistic Control of Acute GvHD: Effectively Down-Regulating T Cell Proliferation and Cytotoxicity with Combined mTOR Inhibition and CD28:CD80/86 Costimulation Blockade

Author

Kozyr, Natalia, primary, Ramakrishnan, Swetha, additional, Polnett, Aneesah, additional, Hamby, Kelly, additional, Tiwari, Divya, additional, Watkins, Benjamin, additional, Deane, Taylor, additional, Stempora, Linda, additional, Elder, Eric, additional, Esiashvili, Natia, additional, Jenkins, Joe, additional, Strobert, Elizabeth, additional, Garcia, Anapatricia, additional, Sharma, Prachi, additional, Courtney, Cynthia, additional, Giver, Cynthia, additional, Waller, Edmund K., additional, Mortari, Angela, additional, Blazar, Bruce R., additional, and Kean, Leslie S., additional

Published
2013
Full Text
View/download PDF

37. Synergistic Control of Acute GvHD: Effectively Down-Regulating T Cell Proliferation and Cytotoxicity with Combined mTOR Inhibition and CD28:CD80/86 Costimulation Blockade.

Author

Kozyr, Natalia, primary, Ramakrishnan, Swetha, additional, Polnett, Aneesah, additional, Hamby, Kelly, additional, Tiwari, Divya, additional, Deane, Taylor, additional, Stempora, Linda, additional, Jenkins, Joe, additional, Strobert, Elizabeth, additional, Garcia, Anapatricia, additional, Sharma, Prachi, additional, Courtney, Cynthia, additional, Panoskaltsis-Mortari, Angela, additional, Giver, Cynthia R., additional, Waller, Edmund K., additional, Blazar, Bruce R., additional, and Kean, Leslie S., additional

Published
2012
Full Text
View/download PDF

39. A novel calcineurin inhibitor– and sirolimus-free anti-LFA-1-based therapy enhances allogeneic islet survival and function in nonhuman primates

Author

Badell, Idelberto R., primary, Turner, Alexandra P., additional, Cano, Jose A., additional, Avila, Jose G., additional, Johnson, Brandi E., additional, Leopardi, Frank V., additional, Swygert, Sarah G., additional, Strobert, Elizabeth A., additional, Kirk, Allan D., additional, and Larsen, Christian P., additional

Published
2009
Full Text
View/download PDF

42. SHIV-1157i and passaged progeny viruses encoding R5 HIV-1 clade C env cause AIDS in rhesus monkeys

Author

Humbert, Michael, primary, Rasmussen, Robert A, additional, Song, Ruijiang, additional, Ong, Helena, additional, Sharma, Prachi, additional, Chenine, Agnès L, additional, Kramer, Victor G, additional, Siddappa, Nagadenahalli B, additional, Xu, Weidong, additional, Else, James G, additional, Novembre, Francis J, additional, Strobert, Elizabeth, additional, O'Neil, Shawn P, additional, and Ruprecht, Ruth M, additional

Published
2008
Full Text
View/download PDF

44. Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization

Author

Jiang, George, primary, Charoenvit, Yupin, additional, Moreno, Alberto, additional, Baraceros, Maria F, additional, Banania, Glenna, additional, Richie, Nancy, additional, Abot, Steve, additional, Ganeshan, Harini, additional, Fallarme, Victoria, additional, Patterson, Noelle B, additional, Geall, Andrew, additional, Weiss, Walter R, additional, Strobert, Elizabeth, additional, Caro-Aquilar, Ivette, additional, Lanar, David E, additional, Saul, Allan, additional, Martin, Laura B, additional, Gowda, Kalpana, additional, Morrissette, Craig R, additional, Kaslow, David C, additional, Carucci, Daniel J, additional, Galinski, Mary R, additional, and Doolan, Denise L, additional

Published
2007
Full Text
View/download PDF

45. Severe Depletion of Mucosal CD4+ T Cells in AIDS-Free Simian Immunodeficiency Virus-Infected Sooty Mangabeys

Author

Gordon, Shari N., primary, Klatt, Nichole R., additional, Bosinger, Steven E., additional, Brenchley, Jason M., additional, Milush, Jeffrey M., additional, Engram, Jessica C., additional, Dunham, Richard M., additional, Paiardini, Mirko, additional, Klucking, Sara, additional, Danesh, Ali, additional, Strobert, Elizabeth A., additional, Apetrei, Cristian, additional, Pandrea, Ivona V., additional, Kelvin, David, additional, Douek, Daniel C., additional, Staprans, Silvija I., additional, Sodora, Donald L., additional, and Silvestri, Guido, additional

Published
2007
Full Text
View/download PDF

49. Development of a Chimeric Anti-CD40 Monoclonal Antibody That Synergizes with LEA29Y to Prolong Islet Allograft Survival

Author

Adams, Andrew B., primary, Shirasugi, Nozomu, additional, Jones, Thomas R., additional, Durham, Megan M., additional, Strobert, Elizabeth A., additional, Cowan, Shannon, additional, Rees, Phyllis, additional, Hendrix, Rose, additional, Price, Karen, additional, Kenyon, Norma S., additional, Hagerty, David, additional, Townsend, Robert, additional, Hollenbaugh, Dianne, additional, Pearson, Thomas C., additional, and Larsen, Christian P., additional

Published
2005
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results