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2. A comparative review of coronary computed tomography angiography and myocardial perfusion imaging.

Author

COMA, Matus, GIBARTI, Claudia, MURIN, Pavol, VICHA, Bronislav, ALUSIK, Daniel, STUDENCAN, Martin, LUKACIN, Stefan, and GAL, Peter

Subjects
MYOCARDIAL perfusion imaging, HEART disease diagnosis, MYOCARDIAL ischemia, CORONARY artery disease, COMPUTED tomography
Abstract

Coronary artery disease remains a leading cause of morbidity and mortality worldwide. Non-invasive imaging techniques have revolutionized the diagnosis and management of coronary artery disease. This review aims to compare the utility and effectiveness of two emerging non-invasive imaging modalities: coronary computed tomography angiography and myocardial perfusion imaging. Thus we provide here a comprehensive overview of the advancements in non-invasive imaging techniques for coronary artery disease assessment. In parallel, we discuss the role of coronary computed tomography angiography and myocardial perfusion imaging in the diagnosis and management of coronary artery disease, their comparative efficacy, and their potential to guide subsequent interventions (Fig. 4, Ref. 70). Text in PDF www.elis.sk [ABSTRACT FROM AUTHOR]

Published
2024
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3. Five-year prognosis of patients with acute myocardial infarction and out-of-hospital cardiac arrest.

Author

ALUSIK, Daniel, CORBA, Andrej, KMEC, Jan, KUBICA, Ignac, ROMANOVA, Lubomira, GAL, Peter, and STUDENCAN, Martin

Abstract

OBJECTIVES: This study aimed to assess the mortality and prognosis of acute myocardial infarction (AMI) patients with out-of-hospital cardiac arrest (OHCA) initially admitted to Department of Anesthesiology and Intensive Care in comparison with patients initially admitted to Cardiac Centre (CC). BACKGROUND: Global acute coronary syndrome (ACS) registries often omit patients with OHCA initially admitted to anaesthesiology and intensive care units. This exclusion may lead to underestimated mortality rates in patients following acute MI worldwide. METHODS: A retrospective analysis was conducted in patients admitted in 2014 to the (Department of Anesthesiology and Intensive Care) at a single center, J.A. Reiman Teaching Hospital in Presov, Slovakia. Survival rates were evaluated in-hospital, at 30 days, and annually over a five-year period. Patients with STEMI and NSTEMI were analyzed separately, particularly during the early in-hospital phase. RESULTS: In the OHCA group, 52% of STEMI patients experienced in-hospital mortality, whereas the CC group reported only 3% mortality. The total hospital mortality for STEMI patients was 6.69%. Among NSTEMI patients in the OHCA group, in-hospital mortality reached 50%, compared to 4.33% in the CC group. The total center mortality for all NSTEMI patients was 6.09%. CONCLUSION: Although the short-term prognosis for MI patients with OHCA is unfavorable, with a 30-day mortality rate of 54.9%, for those who survive the initial 30 d ays following cardiac arrest and are successfully discharged from the hospital, the long-term prognosis aligns with MI patients without OHCA. In light of these findings, the inclusion of all patients with MI (from both OHCA and CC groups) in global ACS registries could significantly raise in-hospital and 30-day mortality rates (Tab. 3, Fig. 4, Ref. 21). Text in PDF www.elis.sk [ABSTRACT FROM AUTHOR]

Published
2024
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4. Sticky platelet syndrome as a cause of acute myocardial infarction in a young soccer player.

Author

Poruban, Tibor, Maxian, Radoslav, Jakubova, Marta, and Studencan, Martin

Subjects
RETURN of spontaneous circulation, BLOOD platelet aggregation, VENTRICULAR septum, CORONARY disease, OXYGENATORS, MYOCARDIAL infarction
Abstract

The article in Cardiology Letters discusses a case of acute myocardial infarction in a 25-year-old soccer player, attributed to Sticky Platelet Syndrome (SPS). The patient collapsed during a match, was resuscitated, and found to have a massive thrombotic occlusion in the left anterior descending artery. Treatment included thromboaspiration, stent implantation, and dual antiplatelet therapy. The patient recovered well, underwent follow-up examinations, and was diagnosed with SPS. The article highlights the importance of recognizing SPS as a cause of myocardial infarction in young athletes. [Extracted from the article]

Published
2024
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5. Care of patients with ST-elevation myocardial infarction:an international analysis of quality indicators in the acute coronary syndrome STEMI Registry of the EURObservational Research Programme and ACVC and EAPCI Associations of the European Society of Cardiology in 11 462 patients

Author

Ludman, Peter, Zeymer, Uwe, Danchin, Nicolas, Kala, Petr, Laroche, Cécile, Sadeghi, Masoumeh, Caporale, Roberto, Shaheen, Sameh Mohamed, Legutko, Jacek, Iakobishvili, Zaza, Alhabib, Khalid F, Motovska, Zuzana, Studencan, Martin, Mimoso, Jorge, Becker, David, Alexopoulos, Dimitrios, Kereseselidze, Zviad, Stojkovic, Sinisa, Zelveian, Parounak, Goda, Artan, Mirrakhimov, Erkin, Bajraktari, Gani, Farhan, Hasan Ali, Šerpytis, Pranas, Raungaard, Bent, Marandi, Toomas, Moore, Alice May, Quinn, Martin, Karjalainen, Pasi Paavo, Tatu-Chitoiu, Gabriel, Gale, Chris P., Maggioni, Aldo P., Weidinger, Franz, Ravkilde, J., Jensen, S. E., Villadsen, A., Villefrance, K., and Skov, C. Schmidt

Subjects
Cardiology, Stroke Volume, General Medicine, Critical Care and Intensive Care Medicine, Ventricular Function, Left, Percutaneous Coronary Intervention, Treatment Outcome, Humans, Prospective Studies, Registries, ST Elevation Myocardial Infarction/epidemiology, Cardiology and Cardiovascular Medicine, Acute Coronary Syndrome/therapy, Quality Indicators, Health Care
Abstract

Aims To use quality indicators to study the management of ST-segment elevation myocardial infarction (STEMI) in different regions. Methods and results Prospective cohort study of STEMI within 24 h of symptom onset (11 462 patients, 196 centres, 26 European Society of Cardiology members, and 3 affiliated countries). The median delay between arrival at a percutaneous cardiovascular intervention (PCI) centre and primary PCI was 40 min (interquartile range 20–74) with 65.8% receiving PCI within guideline recommendation of 60 min. A third of patients (33.2%) required transfer from their initial hospital to one that could perform emergency PCI for whom only 27.2% were treated within the quality indicator recommendation of 120 min. Radial access was used in 56.6% of all primary PCI, but with large geographic variation, from 76.4 to 9.1%. Statins were prescribed at discharge to 98.7% of patients, with little geographic variation. Of patients with a history of heart failure or a documented left ventricular ejection fraction ≤40%, 84.0% were discharged on an angiotensin-converting enzyme inhibitor/angiotensin receptor blocker and 88.7% were discharged on beta-blockers. Conclusion Care for STEMI shows wide geographic variation in the receipt of timely primary PCI, and is in contrast with the more uniform delivery of guideline-recommended pharmacotherapies at time of hospital discharge.

Published
2023
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9. Care of patients with ST-elevation myocardial infarction: an international analysis of quality indicators in the acute coronary syndrome STEMI Registry of the EURObservational Research Programme and ACVC and EAPCI Associations of the European Society of Cardiology in 11 462 patients

Author

Ludman, Peter, Zeymer, Uwe, Danchin, Nicolas, Kala, Petr, Laroche, Cécile, Sadeghi, Masoumeh, Caporale, Roberto, Shaheen, Sameh Mohamed, Legutko, Jacek, Iakobishvili, Zaza, Alhabib, Khalid F, Motovska, Zuzana, Studencan, Martin, Mimoso, Jorge, Becker, David, Alexopoulos, Dimitrios, Kereseselidze, Zviad, Stojkovic, Sinisa, Zelveian, Parounak, and Goda, Artan

Published
2023
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11. Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries

Author

Kristensen, Steen D., Laut, Kristina G., Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F., De Boer, Menko-Jan, Claeys, Marc J., Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K., Kedev, Sasko, Kornowski, Ran, Ludman, Peter F., Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A., Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Mühlberger, Volker, Najafov, Ruslan, Legrand, V., Spuzic, M., Hajric, R., Markota, D., Srdic, S., Jorgova, Julia, Velchev, Vassil, Petrov, Ivo, Nikolic Heitzler, V., Babic, Z., Nicolaides, Evagoras, Christodulides, Theodoros, Georgiou, Panagiota, Jansky, Petr, Stasek, Josef, Terkelsen, Christian Juhl, Galatius, Søren, Sørensen, Rikke, Sobhy, Mohamed, Shal, Ahmed El, Romppanen, Hannu, Müller, Alfred, Rustige, Jörg, Alexopoulos, Dimitrios, Kallikazaros, Ioannis, Papaioannou, Georgios, Becker, David, Ungi, Imre, Kiss, Robert Gabor, Skuladottir, Frida Bjork, Bjornsdottir, Thora K., Cavanagh, Brendan, Twomey, Kathleen, Daly, Kieran, Matetzky, Shlomi, De Luca, Leonardo, Cremonesi, Alberto, Bovenzi, Francesco, Zakke, IIja, Maca, Aija, Narbute, Inga, Antov, S., Koch, Karel T., Mimoso, Jorge, Almeida, Manuel, Pereira, Ernesto, Tatu, Gabriel, Vinereanu, Dragos, DʼAngeli, Cinzia, Nedeljkovic, Milan, Vukcevic, Vladan, Dobric, Milan, Hricak, V., Kovař, F., Kurray, P., Peral, Vincente, Tresserras, Ricard, Regueiro, Ander, Erne, Paul, Rickli, Hans, Windecker, Stephan, Kozan, Omer, Ertas, Gokhan, Kervan, Umit, Birkhead, John, and Sokolov, Yuriy

Published
2014
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13. Reperfusion therapies and in-hospital outcomes for ST-elevation myocardial infarction in Europe: the ACVC-EAPCI EORP STEMI Registry of the European Society of Cardiology

Author

Zeymert, Uwe Ludman, Peter Danchin, Nicolas Kala, Petr and Laroche, Cecile Sadeghi, Masoumeh Caporale, Roberto Shaheen, Sameh Mohamed Legutko, Jacek Iakobsishvili, Zaza Alhabib, Khalid F. Motovska, Zuzana Studencan, Martin Mimoso, Jorge and Becker, David Alexopoulos, Dimitrios Kereseselidze, Zviad and Stojkovic, Sinisa Zelveian, Parounak Goda, Artan and Mirrakhimov, Erkin Bajraktari, Gani Al-Farhan, Hasan and Serpytis, Pranas Raungaard, Bent Marandi, Toomas Moore, Alice May Quinn, Martin Karjalainen, Pasi Paavo and Tatu-Chitolu, Gabriel Gale, Chris P. Maggioni, Aldo P. and Weidinger, Franz ESC

Subjects
cardiovascular diseases
Abstract

Aims The aim of this study was to determine the contemporary use of reperfusion therapy in the European Society of Cardiology (ESC) member and affiliated countries and adherence to ESC clinical practice guidelines in patients with ST-elevation myocardial infarction (STEMI). Methods and results Prospective cohort (EURObservational Research Programme STEMI Registry) of hospitalized STEMI patients with symptom onset

Published
2021

16. TCT CONNECT-249 Real-World Dual Antiplatelet Therapy Following Polymer-free, Sirolimus-Eluting Stent Implantations to Treat Coronary Artery Disease

Author

Krackhardt, Markus Florian, primary, Waliszewski, Matthias, additional, Pansieri, Michel, additional, Lozano, Fernando, additional, Heang, Tay Mok, additional, Hudec, Martin, additional, Studencan, Martin, additional, Mauri, Josepa, additional, Toušek, Petr, additional, Garcia, Bruno, additional, Ahn, Taehoon, additional, Kocka, Viktor, additional, Janek, Bronislav, additional, Sebagh, Laurent, additional, Herberger, Denny, additional, Levy, Gilles, additional, Tomulic, Vjekoslav, additional, and Rischner, Jérôme, additional

Published
2020
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17. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes

Author

Neumann, Franz Josef, Sechtem, Udo, Banning, Adrian Paul, Bonaros, Nikolaos, Bueno, Héctor, Bugiardini, Raffaele, Chieffo, Alaide, Crea, Filippo, Czerny, Martin, Delgado, Victoria, Dendale, Paul, Knuuti, Juhani, Wijns, William, Flachskampf, Frank Arnold, Gohlke, Helmut, Grove, Erik Lerkevang, James, Stefan, Katritsis, Demosthenes, Landmesser, Ulf, Lettino, Maddalena, Matter, Christian M., Nathoe, Hendrik, Niessner, Alexander, Patrono, Carlo, Petronio, Anna Sonia, Pettersen, Steffen E., Piccolo, Raffaele, Piepoli, Massimo Francesco, Popescu, Bogdan A., Räber, Lorenz, Richter, Dimitrios J., Roffi, Marco, Roithinger, Franz X., Shlyakhto, Evgeny, Sibbing, Dirk, Silber, Sigmund, Simpson, Iain A., Sousa-Uva, Miguel, Vardas, Panos, Witkowski, Adam, Zamorano, Jose Luis, Achenbach, Stephan, Agewall, Stefan, Barbato, Emanuele, Bax, Jeroen J., Capodanno, Davide, Cuisset, Thomas, Deaton, Christi, Dickstein, Kenneth, Edvardsen, Thor, Escaned, Javier, Funck-Brentano, Christian, Gersh, Bernard J., Gilard, Martine, Hasdai, David, Hatala, Robert, Mahfoud, Felix, Masip, Josep, Muneretto, Claudio, Prescott, Eva, Saraste, Antti, Storey, Robert F., Svitil, Pavel, Valgimigli, Marco, Aboyans, Victor, Baigent, Colin, Collet, Jean Philippe, Dean, Veronica, Fitzsimons, Donna, Gale, Christopher P., Grobbee, Diederick E., Halvorsen, Sigrun, Hindricks, Gerhard, Iung, Bernard, Jüni, Peter, Katus, Hugo A., Leclercq, Christophe, Lewis, Basil S., Merkely, Bela, Mueller, Christian, Petersen, Steffen, Touyz, Rhian M., Benkhedda, Salim, Metzler, Bernhard, Sujayeva, Volha, Cosyns, Bernard, Kusljugic, Zumreta, Velchev, Vasil, Panayi, Georgios, Kala, Petr, Haahr-Pedersen, Sune Ammentorp, Kabil, Hamza, Ainla, Tiia, Kaukonen, Tomi, Cayla, Guillaume, Pagava, Zurab, Woehrle, Jochen, Kanakakis, John, Toth, Kalman, Gudnason, Thorarinn, Peace, Aaron, Aronson, Doron, Riccio, Carmine, Elezi, Shpend, Mirrakhimov, Erkin, Hansone, Silvija, Sarkis, Antoine, Babarskiene, Ruta, Beissel, Jean, Cassar Maempel, Andrew J., Revenco, Valeriu, de Grooth, G. J., Pejkov, Hristo, Juliebø, Vibeke, Lipiec, Piotr, Santos, Jose, Chioncel, Ovidiu, Duplyakov, Dmitry, Bertelli, Luca, Dikic, Ana Djordjevic, Studencan, Martin, Bunc, Matjaz, Alfonso, Fernando, Back, Magnus, Zellweger, Michael, Addad, Faouzi, Yildirir, Aylin, Sirenko, Yuriy, Clapp, Brian, Neumann, Franz Josef, Sechtem, Udo, Banning, Adrian Paul, Bonaros, Nikolaos, Bueno, Héctor, Bugiardini, Raffaele, Chieffo, Alaide, Crea, Filippo, Czerny, Martin, Delgado, Victoria, Dendale, Paul, Knuuti, Juhani, Wijns, William, Flachskampf, Frank Arnold, Gohlke, Helmut, Grove, Erik Lerkevang, James, Stefan, Katritsis, Demosthenes, Landmesser, Ulf, Lettino, Maddalena, Matter, Christian M., Nathoe, Hendrik, Niessner, Alexander, Patrono, Carlo, Petronio, Anna Sonia, Pettersen, Steffen E., Piccolo, Raffaele, Piepoli, Massimo Francesco, Popescu, Bogdan A., Räber, Lorenz, Richter, Dimitrios J., Roffi, Marco, Roithinger, Franz X., Shlyakhto, Evgeny, Sibbing, Dirk, Silber, Sigmund, Simpson, Iain A., Sousa-Uva, Miguel, Vardas, Panos, Witkowski, Adam, Zamorano, Jose Luis, Achenbach, Stephan, Agewall, Stefan, Barbato, Emanuele, Bax, Jeroen J., Capodanno, Davide, Cuisset, Thomas, Deaton, Christi, Dickstein, Kenneth, Edvardsen, Thor, Escaned, Javier, Funck-Brentano, Christian, Gersh, Bernard J., Gilard, Martine, Hasdai, David, Hatala, Robert, Mahfoud, Felix, Masip, Josep, Muneretto, Claudio, Prescott, Eva, Saraste, Antti, Storey, Robert F., Svitil, Pavel, Valgimigli, Marco, Aboyans, Victor, Baigent, Colin, Collet, Jean Philippe, Dean, Veronica, Fitzsimons, Donna, Gale, Christopher P., Grobbee, Diederick E., Halvorsen, Sigrun, Hindricks, Gerhard, Iung, Bernard, Jüni, Peter, Katus, Hugo A., Leclercq, Christophe, Lewis, Basil S., Merkely, Bela, Mueller, Christian, Petersen, Steffen, Touyz, Rhian M., Benkhedda, Salim, Metzler, Bernhard, Sujayeva, Volha, Cosyns, Bernard, Kusljugic, Zumreta, Velchev, Vasil, Panayi, Georgios, Kala, Petr, Haahr-Pedersen, Sune Ammentorp, Kabil, Hamza, Ainla, Tiia, Kaukonen, Tomi, Cayla, Guillaume, Pagava, Zurab, Woehrle, Jochen, Kanakakis, John, Toth, Kalman, Gudnason, Thorarinn, Peace, Aaron, Aronson, Doron, Riccio, Carmine, Elezi, Shpend, Mirrakhimov, Erkin, Hansone, Silvija, Sarkis, Antoine, Babarskiene, Ruta, Beissel, Jean, Cassar Maempel, Andrew J., Revenco, Valeriu, de Grooth, G. J., Pejkov, Hristo, Juliebø, Vibeke, Lipiec, Piotr, Santos, Jose, Chioncel, Ovidiu, Duplyakov, Dmitry, Bertelli, Luca, Dikic, Ana Djordjevic, Studencan, Martin, Bunc, Matjaz, Alfonso, Fernando, Back, Magnus, Zellweger, Michael, Addad, Faouzi, Yildirir, Aylin, Sirenko, Yuriy, and Clapp, Brian

Abstract

Coronary artery disease (CAD) is a pathological process characterized by atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive. This process can be modified by lifestyle adjustments, pharmacological therapies, and invasive interventions designed to achieve disease stabilization or regression. The disease can have long, stable periods but can also become unstable at any time, typically due to an acute atherothrombotic event caused by plaque rupture or erosion. However, the disease is chronic, most often progressive, and hence serious, even in clinically apparently silent periods. The dynamic nature of the CAD process results in various clinical presentations, which can be conveniently categorized as either acute coronary syndromes (ACS) or chronic coronary syndromes (CCS). The Guidelines presented here refer to the management of patients with CCS. The natural history of CCS is illustrated in Figure 1.

Published
2020

18. Reperfusion therapies and in-hospital outcomes for ST-elevation myocardial infarction in Europe: the ACVC-EAPCI EORP STEMI Registry of the European Society of Cardiology.

Author

Zeymer, Uwe, Ludman, Peter, Danchin, Nicolas, Kala, Petr, Laroche, Cécile, Sadeghi, Masoumeh, Caporale, Roberto, Shaheen, Sameh Mohamed, Legutko, Jacek, Iakobsishvili, Zaza, Alhabib, Khalid F, Motovska, Zuzana, Studencan, Martin, Mimoso, Jorge, Becker, David, Alexopoulos, Dimitrios, Kereseselidze, Zviad, Stojkovic, Sinisa, Zelveian, Parounak, and Goda, Artan

Subjects
FIBRINOLYSIS, CARDIOLOGY, PERCUTANEOUS coronary intervention, REPERFUSION, MORTALITY
Abstract

Aims  The aim of this study was to determine the contemporary use of reperfusion therapy in the European Society of Cardiology (ESC) member and affiliated countries and adherence to ESC clinical practice guidelines in patients with ST-elevation myocardial infarction (STEMI). Methods and results  Prospective cohort (EURObservational Research Programme STEMI Registry) of hospitalized STEMI patients with symptom onset <24 h in 196 centres across 29 countries. A total of 11 462 patients were enrolled, for whom primary percutaneous coronary intervention (PCI) (total cohort frequency: 72.2%, country frequency range 0–100%), fibrinolysis (18.8%; 0–100%), and no reperfusion therapy (9.0%; 0–75%) were performed. Corresponding in-hospital mortality rates from any cause were 3.1%, 4.4%, and 14.1% and overall mortality was 4.4% (country range 2.5–5.9%). Achievement of quality indicators for reperfusion was reported for 92.7% (region range 84.8–97.5%) for the performance of reperfusion therapy of all patients with STEMI <12 h and 54.4% (region range 37.1–70.1%) for timely reperfusion. Conclusions  The use of reperfusion therapy for STEMI in the ESC member and affiliated countries was high. Primary PCI was the most frequently used treatment and associated total in-hospital mortality was below 5%. However, there was geographic variation in the use of primary PCI, which was associated with differences in in-hospital mortality. [ABSTRACT FROM AUTHOR]

Published
2021
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22. TCT-728 Polymer-free sirolimus eluting stents in a large scale all comers population

Author

Krackhardt, Markus Florian, primary, Waliszewski, Matt, additional, Kocka, Viktor, additional, Utech, Andreas, additional, Lustermann, Meik, additional, Hudec, Martin, additional, Studencan, Martin, additional, Yu, Jiangtao, additional, Schwefer, Markus, additional, Jeong, Myung Ho, additional, Ahn, Taehoon, additional, Wan Ahmad, Wan Azman, additional, Boxberger, Michael, additional, and Leschke, Matthias, additional

Published
2017
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23. Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries

Author

Kristensen, Steen D., Laut, Kristina G., Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F., De Boer, Menko-Jan, Claeys, Marc J., Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K., Kedev, Sasko, Kornowski, Ran, Ludman, Peter F., Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A., Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Mühlberger, Volker, Legrand, V., Spuzic, M., Hajric, R., Markota, D., Srdic, S., Jorgova, Julia, Velchev, Vassil, Petrov, Ivo, Nikolic Heitzler, V., Babic, Z., Nicolaides, Evagoras, Christodulides, Theodoros, Georgiou, Panagiota, Jansky, Petr, Stasek, Josef, Terkelsen, Christian Juhl, Galatius, Søren, Sørensen, Rikke, Shal, Ahmed El, Romppanen, Hannu, Müller, Alfred, Rustige, Jörg, Alexopoulos, Dimitrios, Kallikazaros, Ioannis, Papaioannou, Georgios, Becker, David, Ungi, Imre, Kiss, Robert Gabor, Skuladottir, Frida Bjork, Bjornsdottir, Thora K., Cavanagh, Brendan, Twomey, Kathleen, Daly, Kieran, Matetzky, Shlomi, De Luca, Leonardo, Cremonesi, Alberto, Bovenzi, Francesco, Zakke, IIja, Maca, Aija, Narbute, Inga, Antov, S., Koch, Karel T., Mimoso, Jorge, Almeida, Manuel, Pereira, Ernesto, Tatu, Gabriel, Vinereanu, Dragos, D'Angeli, Cinzia, Nedeljkovic, Milan, Vukcevic, Vladan, Dobric, Milan, Hricak, V., Kovař, F., Kurray, P., Peral, Vincente, Tresserras, Ricard, Regueiro, Ander, Erne, Paul, Rickli, Hans, Windecker, Stephan, Kozan, Omer, Ertas, Gokhan, Kervan, Umit, Birkhead, John, Sokolov, Yuriy, Kristensen, Steen D., Laut, Kristina G., Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F., De Boer, Menko-Jan, Claeys, Marc J., Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K., Kedev, Sasko, Kornowski, Ran, Ludman, Peter F., Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A., Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Mühlberger, Volker, Legrand, V., Spuzic, M., Hajric, R., Markota, D., Srdic, S., Jorgova, Julia, Velchev, Vassil, Petrov, Ivo, Nikolic Heitzler, V., Babic, Z., Nicolaides, Evagoras, Christodulides, Theodoros, Georgiou, Panagiota, Jansky, Petr, Stasek, Josef, Terkelsen, Christian Juhl, Galatius, Søren, Sørensen, Rikke, Shal, Ahmed El, Romppanen, Hannu, Müller, Alfred, Rustige, Jörg, Alexopoulos, Dimitrios, Kallikazaros, Ioannis, Papaioannou, Georgios, Becker, David, Ungi, Imre, Kiss, Robert Gabor, Skuladottir, Frida Bjork, Bjornsdottir, Thora K., Cavanagh, Brendan, Twomey, Kathleen, Daly, Kieran, Matetzky, Shlomi, De Luca, Leonardo, Cremonesi, Alberto, Bovenzi, Francesco, Zakke, IIja, Maca, Aija, Narbute, Inga, Antov, S., Koch, Karel T., Mimoso, Jorge, Almeida, Manuel, Pereira, Ernesto, Tatu, Gabriel, Vinereanu, Dragos, D'Angeli, Cinzia, Nedeljkovic, Milan, Vukcevic, Vladan, Dobric, Milan, Hricak, V., Kovař, F., Kurray, P., Peral, Vincente, Tresserras, Ricard, Regueiro, Ander, Erne, Paul, Rickli, Hans, Windecker, Stephan, Kozan, Omer, Ertas, Gokhan, Kervan, Umit, Birkhead, John, and Sokolov, Yuriy

Abstract

Aims Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries. Methods and results A cross-sectional descriptive study based on aggregated country-level data on the use of reperfusion therapy in patients admitted with STEMI during 2010 or 2011. Thirty-seven ESC countries were able to provide data from existing national or regional registries. In countries where no such registries exist, data were based on best expert estimates. Data were collected on the use of STEMI reperfusion treatment and mortality, the numbers of cardiologists, and the availability of PPCI facilities in each country. Our survey provides a brief data summary of the degree of variation in reperfusion therapy across Europe. The number of PPCI procedures varied between countries, ranging from 23 to 884 per million inhabitants. Primary percutaneous coronary intervention and thrombolysis were the dominant reperfusion strategy in 33 and 4 countries, respectively. The mean population served by a single PPCI centre with a 24-h service 7 days a week ranged from 31 300 inhabitants per centre to 6 533 000 inhabitants per centre. Twenty-seven of the total 37 countries participated in a former survey from 2007, and major increases in PPCI utilization were observed in 13 of these countries. Conclusion Large variations in reperfusion treatment are still present across Europe. Countries in Eastern and Southern Europe reported that a substantial number of STEMI patients are not receiving any reperfusion therapy. Implementation of the best reperfusion therapy as recommended in the guidelines should be encouraged

Published
2017

24. Differences between Slovak and Dutch patients scheduled for coronary artery bypass graft surgery regarding clinical and psychosocial predictors of physical and mental health-related quality of life.

Author

El-Baz, Noha, Ondusova, Daniela, Studencan, Martin, Rosenberger, Jaroslav, Reijneveld, Sijmen A., van Dijk, Jitse P., and Middel, Berrie

Subjects
RESEARCH, CORONARY artery bypass, SCIENTIFIC observation, ACADEMIC medical centers, CONFIDENCE intervals, PSYCHOLOGY of cardiac patients, SLOVAKS, MENTAL health, REGRESSION analysis, HEALTH surveys, FISHER exact test, CRONBACH'S alpha, PSYCHOLOGICAL tests, T-test (Statistics), CORONARY artery disease, QUALITY of life, QUESTIONNAIRES, DESCRIPTIVE statistics, CHI-squared test, RESEARCH funding, DATA analysis software, PROBABILITY theory
Abstract

Background: Differences in health-related quality of life in coronary artery disease patients and associated factors between patients of central and western European descent are rarely investigated. We aim to test differences between Dutch and Slovak health-related quality of life, whether nationality predicted health-related quality of life and if standardised beta weights of health-related quality of life determinants differ across countries. Design: An observational multicentre study at university cardiac centres in the Netherlands and Slovakia. Methods: In 226 coronary artery disease patients, health-related quality of life was measured by the Short Form Health Survey 36, anxiety and depression were measured using the Hospital Anxiety and Depression Scale, and type D personality was assessed with the 14-item Type D Scale. Multivariate analysis was used to explore the effect of patient characteristics on the physical and mental component summaries. Estimates of each predictor’s beta value of the physical and mental component summaries in the Slovak and Dutch patient sample were separately calculated using the Cummings criterion for comparison of two independent betas. Results: Stronger predictors of physical health-related quality of life in Slovak patients were educational level, current smoking, poor functional status, history of diabetes and amount of social support. In Dutch patients, only more symptoms of depression was a stronger predictor (P<0.05). Regarding Slovak mental health-related quality of life, stronger predictors were educational level, current smoking and amount of social support. Female gender, history of myocardial infarction and more symptoms of depression were stronger predictors in Dutch patients (P<0.05). Conclusion: Descent and differences between both populations in determinants of health-related quality of life should be considered while planning care, follow-up, health education and rehabilitation. [ABSTRACT FROM AUTHOR]

Published
2018
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25. Socioeconomic inequalities in quality of life and psychological outcomes among cardiac patients

Author

Skodova, Zuzana, Nagyova, Iveta, van Dijk, Jitse, Sudzinova, Adriana, Vargova, Helena, Rosenberger, Jaroslav, Middel, Berrie, Studencan, Martin, and Reijneveld, Sijmen

Abstract

Abstract: Objectives:: The aim of this article is to explore socioeconomic inequalities in the psychological characteristics (psychological well-being, perceived mental health status) and perceived quality of life among cardiac patients. Methods:: A structured interview was conducted with 362 patients (32% women, mean age 56 ± 7.3 years) referred for coronary angiography. The GHQ-28 was used to measure psychological well-being, the SF-36 for perceived mental health status. Income and education indicated socioeconomic position. Logistic regressions were employed, adjusted for age, gender, functional status and severity of disease. Results:: Patients with low income or education had a higher probability of having poor psychological well-being compared to participants with high income or education (OR 5.5,CI 2.32-12.80; OR 3.1,CI 1.52-6.37 resp.), and were also more likely to have worse mental health status (OR2.9,CI 1.02-8.51;OR 4.8,CI 1.36-16.99 resp.), and low quality of life (OR 2.9,CI 1.02-8.51; OR 4.8,CI 1.36-16.99 resp.). Conclusions:: Socioeconomic status was found to be negatively associated with the psychological outcomes and quality of life among cardiac patients. Socioeconomic inequalities should be taken into account when designing suitably-adapted interventions focusing on psychosocial factors among cardiac patients.

Published
2024
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27. Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011:current status in 37 ESC countries

Author

Kristensen, Steen D, Laut, Kristina G, Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F, De Boer, Menko-Jan, Claeys, Marc J, Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K, Kedev, Sasko, Kornowski, Ran, Ludman, Peter F, Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A, Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Kristensen, Steen D, Laut, Kristina G, Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F, De Boer, Menko-Jan, Claeys, Marc J, Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K, Kedev, Sasko, Kornowski, Ran, Ludman, Peter F, Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A, Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, and Widimsky, Petr

Abstract

AIMS: Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries.METHODS AND RESULTS: A cross-sectional descriptive study based on aggregated country-level data on the use of reperfusion therapy in patients admitted with STEMI during 2010 or 2011. Thirty-seven ESC countries were able to provide data from existing national or regional registries. In countries where no such registries exist, data were based on best expert estimates. Data were collected on the use of STEMI reperfusion treatment and mortality, the numbers of cardiologists, and the availability of PPCI facilities in each country. Our survey provides a brief data summary of the degree of variation in reperfusion therapy across Europe. The number of PPCI procedures varied between countries, ranging from 23 to 884 per million inhabitants. Primary percutaneous coronary intervention and thrombolysis were the dominant reperfusion strategy in 33 and 4 countries, respectively. The mean population served by a single PPCI centre with a 24-h service 7 days a week ranged from 31 300 inhabitants per centre to 6 533 000 inhabitants per centre. Twenty-seven of the total 37 countries participated in a former survey from 2007, and major increases in PPCI utilization were observed in 13 of these countries.CONCLUSION: Large variations in reperfusion treatment are still present across Europe. Countries in Eastern and Southern Europe reported that a substantial number of STEMI patients are not receiving any reperfusion therapy. Implementation of the best reperfusion therapy as recommended in the guidelines should be encouraged.

Published
2014

30. Sense of coherence as a predictor of health-related behaviours among patients with coronary heart disease.

Author

Silarova, Barbora, Nagyova, Iveta, Rosenberger, Jaroslav, Studencan, Martin, Ondusova, Daniela, Reijneveld, Sijmen A, and van Dijk, Jitse P

Subjects
CORONARY disease, CORONARY heart disease surgery, CONFIDENCE intervals, CORONARY artery bypass, ALCOHOL drinking, HEALTH behavior, HEALTH promotion, INTERVIEWING, LONGITUDINAL method, RESEARCH methodology, MYOCARDIAL revascularization, NUTRITION, PATH analysis (Statistics), QUESTIONNAIRES, REGRESSION analysis, RESEARCH, SELF-evaluation, SMOKING, TRANSLUMINAL angioplasty, PHYSICAL activity, ODDS ratio, PSYCHOLOGY
Abstract

Aims: A high sense of coherence (SOC) has been found to be associated with favourable health-related behaviours. However, evidence is for the most part lacking on the influence of SOC on health-related behaviours among coronary heart disease patients. The aim of this study was to explore the association between SOC at baseline and smoking status, nutrition behaviour, physical exercise and alcohol consumption of coronary heart disease patients 12–28 months after they had undergone different cardiac treatments. Methods: A total of 179 coronary heart disease patients (mean age 58.32±6.54 years, 19% female) were interviewed before coronary angiography and 12–28 months after. Self-report data about health-related behaviours were obtained via a structured interview. SOC was measured using the 13-item Orientation to Life Questionnaire. The relationship between SOC and health-related behaviours was examined using regression and cross-lagged path analyses. Results: SOC at baseline predicted non-smoking and quitting smoking: odds ratio (OR) (95% confidence interval (CI)) per unit increase (over range 38–91) was 1.11 (1.03–1.19) and 1.09 (1.01–1.17), respectively. Moreover, baseline SOC predicted healthy nutrition behaviour among percutaneous coronary intervention patients: the OR per unit increase was 1.08 (95% CI: 1.01–1.15). Lastly, SOC at baseline predicted improvement in alcohol consumption at follow-up among coronary artery bypass grafting patients (standard score result: –0.15, p<0.05). Conclusion: Coronary heart disease patients with a low SOC before treatment are less likely to improve health behaviours after cardiac treatment and should thus get additional attention in health promotion. [ABSTRACT FROM AUTHOR]

Published
2014
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31. Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries

Author

Kristensen, Steen D., Laut, Kristina G., Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F., De Boer, Menko-Jan, Claeys, Marc J., Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K., Kedev, Sasko, Kornowski, Ran, Ludman, Peter F., Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A., Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Mühlberger, Volker, Legrand, V., Spuzic, M., Hajric, R., Markota, D., Srdic, S., Jorgova, Julia, Velchev, Vassil, Petrov, Ivo, Nikolic Heitzler, V., Babic, Z., Nicolaides, Evagoras, Christodulides, Theodoros, Georgiou, Panagiota, Jansky, Petr, Stasek, Josef, Terkelsen, Christian Juhl, Galatius, Søren, Sørensen, Rikke, Shal, Ahmed El, Romppanen, Hannu, Müller, Alfred, Rustige, Jörg, Alexopoulos, Dimitrios, Kallikazaros, Ioannis, Papaioannou, Georgios, Becker, David, Ungi, Imre, Kiss, Robert Gabor, Skuladottir, Frida Bjork, Bjornsdottir, Thora K., Cavanagh, Brendan, Twomey, Kathleen, Daly, Kieran, Matetzky, Shlomi, De Luca, Leonardo, Cremonesi, Alberto, Bovenzi, Francesco, Zakke, IIja, Maca, Aija, Narbute, Inga, Antov, S., Koch, Karel T., Mimoso, Jorge, Almeida, Manuel, Pereira, Ernesto, Tatu, Gabriel, Vinereanu, Dragos, D'Angeli, Cinzia, Nedeljkovic, Milan, Vukcevic, Vladan, Dobric, Milan, Hricak, V., Kovař, F., Kurray, P., Peral, Vincente, Tresserras, Ricard, Regueiro, Ander, Erne, Paul, Rickli, Hans, Windecker, Stephan, Kozan, Omer, Ertas, Gokhan, Kervan, Umit, Birkhead, John, Sokolov, Yuriy, Kristensen, Steen D., Laut, Kristina G., Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F., De Boer, Menko-Jan, Claeys, Marc J., Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K., Kedev, Sasko, Kornowski, Ran, Ludman, Peter F., Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A., Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Mühlberger, Volker, Legrand, V., Spuzic, M., Hajric, R., Markota, D., Srdic, S., Jorgova, Julia, Velchev, Vassil, Petrov, Ivo, Nikolic Heitzler, V., Babic, Z., Nicolaides, Evagoras, Christodulides, Theodoros, Georgiou, Panagiota, Jansky, Petr, Stasek, Josef, Terkelsen, Christian Juhl, Galatius, Søren, Sørensen, Rikke, Shal, Ahmed El, Romppanen, Hannu, Müller, Alfred, Rustige, Jörg, Alexopoulos, Dimitrios, Kallikazaros, Ioannis, Papaioannou, Georgios, Becker, David, Ungi, Imre, Kiss, Robert Gabor, Skuladottir, Frida Bjork, Bjornsdottir, Thora K., Cavanagh, Brendan, Twomey, Kathleen, Daly, Kieran, Matetzky, Shlomi, De Luca, Leonardo, Cremonesi, Alberto, Bovenzi, Francesco, Zakke, IIja, Maca, Aija, Narbute, Inga, Antov, S., Koch, Karel T., Mimoso, Jorge, Almeida, Manuel, Pereira, Ernesto, Tatu, Gabriel, Vinereanu, Dragos, D'Angeli, Cinzia, Nedeljkovic, Milan, Vukcevic, Vladan, Dobric, Milan, Hricak, V., Kovař, F., Kurray, P., Peral, Vincente, Tresserras, Ricard, Regueiro, Ander, Erne, Paul, Rickli, Hans, Windecker, Stephan, Kozan, Omer, Ertas, Gokhan, Kervan, Umit, Birkhead, John, and Sokolov, Yuriy

Abstract

Aims Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries. Methods and results A cross-sectional descriptive study based on aggregated country-level data on the use of reperfusion therapy in patients admitted with STEMI during 2010 or 2011. Thirty-seven ESC countries were able to provide data from existing national or regional registries. In countries where no such registries exist, data were based on best expert estimates. Data were collected on the use of STEMI reperfusion treatment and mortality, the numbers of cardiologists, and the availability of PPCI facilities in each country. Our survey provides a brief data summary of the degree of variation in reperfusion therapy across Europe. The number of PPCI procedures varied between countries, ranging from 23 to 884 per million inhabitants. Primary percutaneous coronary intervention and thrombolysis were the dominant reperfusion strategy in 33 and 4 countries, respectively. The mean population served by a single PPCI centre with a 24-h service 7 days a week ranged from 31 300 inhabitants per centre to 6 533 000 inhabitants per centre. Twenty-seven of the total 37 countries participated in a former survey from 2007, and major increases in PPCI utilization were observed in 13 of these countries. Conclusion Large variations in reperfusion treatment are still present across Europe. Countries in Eastern and Southern Europe reported that a substantial number of STEMI patients are not receiving any reperfusion therapy. Implementation of the best reperfusion therapy as recommended in the guidelines should be encouraged

32. Perspectives: Rationale and design of the ISACS-TC (International Survey of Acute Coronary Syndromes in Transitional Countries) project

Author

Bugiardini, Raffaele, Badimon, Lina, Manfrini, Olivia, Investigators, on the behalf of the ISACS-TC, Boytsov, Sergei, Bozidarka, Knezevic, Daullxhiu, Irfan, Dilic, Mirza, Dorobantu, Maria, Erglis, Andreis, Gafarov, Valery, Gale, Christopher P., Goncalvesova, Eva, Goudev, Asen, Gustiene, Olivja, Hall, Alistair, Karpova, Irena, Kedev, Sasko, Manak, Nicolay, Milicic, Davor, Ostojic, Miograd, Parkhomenko, Alexander N., Popovici, Mihail, Studenkan, Martin, Toth, Kalman, Trninic, Dijana, Vasiljevic, Zorana, Zakke, Ilja, Zaliunas, Remigijus, Bugiardini, Raffaele, Vaccarino, Viola, Manfrini, Olivia, Badimon, Lina, Manak, Nicolay, Karpova, Irena, Dilic, Mirza, Trninic, Dijana, Goudev, Assen, Milicic, Davor, Toth, Kalman, Daullxhiu, Irfan, Erglis, Andrejs, Zakke, Ilja, Zaliunas, Remigius, Gustiene, Olivija, Kedev, Sasko, Popovici, Mihail, Knezevic, Bozidarka, Boytsov, Sergei, Gafarov, Valery, Dorubantu, Maria, Vasiljevic, Zorana, Ojstoic, Miodrag, Goncalvesova, Eva, Studencan, Martin, Parkhomenko, Alexander N, Hall, Alistair, Gale, Christopher, Karpova, Irena, Manak, Nicoly, Lovric, Milica, Korac, Robert, Mandic, Dragana, Vujovic, Vlado, Blagojevic, Milan, Milekic, Jovana, Trendafilova, Elina, Somleva, Desislava, Krivokapic, Ljiljana, Rajovic, Gordana, Sahmanovic, Omer, Saranovic, Mirko, Radoman, Colovic, Tomic, Slavica Cvijovic, Ljubic, Vujica, Velickovic, Milan, Radojicic, Sonja, Arsenescu-Georfescu, Catalina, Garbea, Smaranda, Radu, Capalneanu, Olinic, Dan, Calin, Pop, Chifor, Alexandru, Babes, Katalin, lonescu, Dan Dominic, Craiu, Elvira, Petrescu, Hie, Magda, Ionescu, Luminita, Serban, Benedek, Imre, Marinescu, Sorin, Tiberiu, Nanea, Gheorghe, Gabriela, Malaescu, Ion, Trocan, Nicolae, Doina, Dimulescu, Macarie, Cezar, Putnikovic, Biljana, Arandjelovic, Aleksandra, Nikolic, Natasa Markovic, Zdravkovic, Marija, Saric, Jelena, Radovanovic, Slavica, Matic, Irena, Srbljak, Nebojsad, Davidovic, Goran, Simovic, Stefan, Zivkovic, Sinisa, Petkovic-Curic, Slavenka, Studencan, Martin, and Parkhomenko, Alexander N

Abstract

During the past 10 years, the health of people in Eastern Europe and the former Soviet Union has undergone changes very different from the health patterns seen in their Western counterparts. Mortality from cardiovascular disease has been decreasing continuously in the USA and many Western European countries, but it has increased or remained unchanged in many of the states of Eastern Europe. Analysis of this phenomenon has been hindered by insufficient information. The International Registry of Acute Coronary Syndromes registry study in Transitional Countries (ISACS-TC) is both a retrospective—over a 1-year period—and prospective study which was designed in order to obtain data of patients with acute coronary syndromes (ACSs) in countries with economy in transition in Central and Eastern Europe, and herewith control and optimize internationally guideline recommended therapies in these countries. Adhesion to the project was given by 112 Collaborating Centres in 17 countries with economy in transition (Albania, Bosnia and Herzegovina, Belarius, Bulgaria, Croatia, Hungary, Kosovo, Latvia, Lithuania, Macedonia, Moldova, Montenegro, Romania, Russian Federation, Serbia, Slovakia, Slovenia, and Ukraine). A total of 47 cluster sites in 11 countries in Central and Eastern Europe are currently collaborating in ISACS-TC. The registry encourages optimal individualization of evidence-based therapies and the international patient body ensures good representation of multiple practice patterns. It may help to make an additional improvement in clinical outcomes of countries with economy in transition.

Published
2014
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33. Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries.

Author

Widimsky P, Wijns W, Fajadet J, de Belder M, Knot J, Aaberge L, Andrikopoulos G, Baz JA, Betriu A, Claeys M, Danchin N, Djambazov S, Erne P, Hartikainen J, Huber K, Kala P, Klinceva M, Kristensen SD, Ludman P, Ferre JM, Merkely B, Milicic D, Morais J, Noc M, Opolski G, Ostojic M, Radovanovic D, De Servi S, Stenestrand U, Studencan M, Tubaro M, Vasiljevic Z, Weidinger F, Witkowski A, and Zeymer U

Subjects
Angioplasty, Balloon, Coronary statistics & numerical data, Europe epidemiology, Health Services Accessibility, Hospital Mortality, Hospitalization statistics & numerical data, Humans, Incidence, Myocardial Infarction epidemiology, Myocardial Reperfusion statistics & numerical data, Needs Assessment, Residence Characteristics, Time Factors, Myocardial Infarction therapy, Myocardial Reperfusion methods
Abstract

Aims: Patient access to reperfusion therapy and the use of primary percutaneous coronary intervention (p-PCI) or thrombolysis (TL) varies considerably between European countries. The aim of this study was to obtain a realistic contemporary picture of how patients with ST elevation myocardial infarction (STEMI) are treated in different European countries., Methods and Results: The chairpersons of the national working groups/societies of interventional cardiology in European countries and selected experts known to be involved in the national registries joined the writing group upon invitation. Data were collected about the country and any existing national STEMI or PCI registries, about STEMI epidemiology, and treatment in each given country and about PCI and p-PCI centres and procedures in each country. Results from the national and/or regional registries in 30 countries were included in this analysis. The annual incidence of hospital admission for any acute myocardial infarction (AMI) varied between 90-312/100 thousand/year, the incidence of STEMI alone ranging from 44 to 142. Primary PCI was the dominant reperfusion strategy in 16 countries and TL in 8 countries. The use of a p-PCI strategy varied between 5 and 92% (of all STEMI patients) and the use of TL between 0 and 55%. Any reperfusion treatment (p-PCI or TL) was used in 37-93% of STEMI patients. Significantly less reperfusion therapy was used in those countries where TL was the dominant strategy. The number of p-PCI procedures per million per year varied among countries between 20 and 970. The mean population served by a single p-PCI centre varied between 0.3 and 7.4 million inhabitants. In those countries offering p-PCI services to the majority of their STEMI patients, this population varied between 0.3 and 1.1 million per centre. In-hospital mortality of all consecutive STEMI patients varied between 4.2 and 13.5%, for patients treated by TL between 3.5 and 14% and for patients treated by p-PCI between 2.7 and 8%. The time reported from symptom onset to the first medical contact (FMC) varied between 60 and 210 min, FMC-needle time for TL between 30 and 110 min, and FMC-balloon time for p-PCI between 60 and 177 min., Conclusion: Most North, West, and Central European countries used p-PCI for the majority of their STEMI patients. The lack of organized p-PCI networks was associated with fewer patients overall receiving some form of reperfusion therapy.

Published
2010
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