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9 results on '"Stuhlert, Caroline"'

1. Course of Vitamin D Levels in Newly Diagnosed Non-Metastatic Breast Cancer Patients over One Year with Quarterly Controls and Substitution

Author

Zemlin, Cosima, primary, Altmayer, Laura, additional, Lang, Marina, additional, Schleicher, Julia Theresa, additional, Stuhlert, Caroline, additional, Wörmann, Carolin, additional, Scherer, Laura-Sophie, additional, Thul, Ida Clara, additional, Spenner, Lisanne Sophie, additional, Simon, Jana Alisa, additional, Wind, Alina, additional, Kaiser, Elisabeth, additional, Weber, Regine, additional, Goedicke-Fritz, Sybelle, additional, Wagenpfeil, Gudrun, additional, Zemlin, Michael, additional, Solomayer, Erich-Franz, additional, Reichrath, Jörg, additional, and Müller, Carolin, additional

Published
2024
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2. A Plea for Monitoring Serum Selenium Levels in Breast Cancer Patients: Selenium Deficiency Is Rare during the First Year of Therapy, and Selenium Supplementation Is Associated with Elevated Risk of Overdosing.

Author

Altmayer, Laura Alicia, Lang, Marina, Schleicher, Julia Theresa, Stuhlert, Caroline, Wörmann, Carolin, Scherer, Laura-Sophie, Thul, Ida Clara, Spenner, Lisanne Sophie, Simon, Jana Alisa, Wind, Alina, Tokcan, Mert, Kaiser, Elisabeth, Weber, Regine, Goedicke-Fritz, Sybelle, Wagenpfeil, Gudrun, Zemlin, Michael, Solomayer, Erich-Franz, Reichrath, Jörg, Müller, Carolin, and Zemlin, Cosima

Abstract

(1) Background: The role of selenium in cancer biology remains poorly understood. Our aim was to study the course of selenium serum levels and the use of selenium supplements during breast cancer therapy. (2) Methods: Serum selenium levels, clinical–pathological data, selenium supplementation, and lifestyle factors were monitored quarterly over one year. (3) Results: A total of 110 non-metastatic breast cancer patients were enrolled in the prospective observational “BEGYN-1” study. At baseline, 2.9% of patients were selenium-deficient (<50 ng/mL), 1.9% were overdosed (>120 ng/mL), and 6.4% received substitution. The median selenium level was 81.5 ng/mL and ranged between 78.7 and 84.5 ng/mL within the year. A total of 25.3% of the patients received supplementation, resulting in significantly higher selenium levels (p < 0.05). A total of 8.7–28.6% of the patients using supplements were overdosed. Selenium levels strongly correlated with mushroom consumption (p = 0.003), but no association was found with therapy or clinical characteristics. (4) Conclusions: Although selenium deficiency is rare, serum selenium levels should be assessed in breast cancer patients. Mushrooms and nuts should be preferred over supplements to correct selenium deficiency. Ruling out selenium deficiency helps prevent the risk of selenosis and avoid unnecessary, costly supplementation in patients who are often financially burdened due to their disease. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Improved awareness of physical activities is associated with a gain of fitness and a stable body weight in breast cancer patients during the first year of antineoplastic therapy: the BEGYN-1 study

Author

Zemlin, Cosima, primary, Schleicher, Julia Theresa, additional, Altmayer, Laura, additional, Stuhlert, Caroline, additional, Wörmann, Carolin, additional, Lang, Marina, additional, Scherer, Laura-Sophie, additional, Thul, Ida Clara, additional, Spenner, Lisanne Sophie, additional, Simon, Jana Alisa, additional, Wind, Alina, additional, Kaiser, Elisabeth, additional, Weber, Regine, additional, Goedicke-Fritz, Sybelle, additional, Wagenpfeil, Gudrun, additional, Zemlin, Michael, additional, Steffgen, Georges, additional, Solomayer, Erich-Franz, additional, and Müller, Carolin, additional

Published
2023
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4. Prevalence and Relevance of Vitamin D Deficiency in Newly Diagnosed Breast Cancer Patients: A Pilot Study

Author

Zemlin, Cosima, primary, Altmayer, Laura, additional, Stuhlert, Caroline, additional, Schleicher, Julia Theresa, additional, Wörmann, Carolin, additional, Lang, Marina, additional, Scherer, Laura-Sophie, additional, Thul, Ida Clara, additional, Spenner, Lisanne Sophie, additional, Simon, Jana Alisa, additional, Wind, Alina, additional, Kaiser, Elisabeth, additional, Weber, Regine, additional, Goedicke-Fritz, Sybelle, additional, Wagenpfeil, Gudrun, additional, Zemlin, Michael, additional, Solomayer, Erich-Franz, additional, Reichrath, Jörg, additional, and Müller, Carolin, additional

Published
2023
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5. Vitamin D deficiency is frequent and selenium deficiency is rare in newly diagnosed breast cancer patients

Author

Zemlin, Cosima, primary, Altmayer, Laura, additional, Stuhlert, Caroline, additional, Schleicher, Julia Theresa, additional, Wörmann, Carolin, additional, Lang, Marina, additional, Scherer, Laura-Sophie, additional, Thul, Ida Clara, additional, Spenner, Lisanne Sophie, additional, Simon, Jana Alisa, additional, Wind, Alina, additional, Kaiser, Elisabeth, additional, Stutz, Regine, additional, Goedicke-Fritz, Sybelle, additional, Wagenpfeil, Gudrun, additional, Zemlin, Michael, additional, Solomayer, Erich-Franz, additional, and Müller, Carolin, additional

Published
2022
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6. Longitudinal Assessment of Physical Activity, Fitness, Body Composition, Immunological Biomarkers, and Psychological Parameters During the First Year After Diagnosis in Women With Non-Metastatic Breast Cancer: The BEGYN Study Protocol

Author

Zemlin, Cosima, primary, Stuhlert, Caroline, additional, Schleicher, Julia Theresa, additional, Wörmann, Carolin, additional, Altmayer, Laura, additional, Lang, Marina, additional, Scherer, Laura-Sophie, additional, Thul, Ida Clara, additional, Müller, Carolin, additional, Kaiser, Elisabeth, additional, Stutz, Regine, additional, Goedicke-Fritz, Sybelle, additional, Ketter, Laura, additional, Zemlin, Michael, additional, Wagenpfeil, Gudrun, additional, Steffgen, Georges, additional, and Solomayer, Erich-Franz, additional

Published
2021
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7. Longitudinal Assessment of Physical Activity, Fitness, Body Composition, Immunological Biomarkers, and Psychological Parameters During the First Year After Diagnosis in Women With Non-Metastatic Breast Cancer: The BEGYN Study Protocol

Author

Zemlin, Cosima, Stuhlert, Caroline, Schleicher, Julia Theresa, Wörmann, Caroline, Altmayer, Laura, Lang, Marina, Scherer, Laura-Sophie, Thul, Ida Clara, Müller, Carolin, Kaiser, Elisabeth, Stutz, Regine, Goedecke-Fritz, Sybille, Ketter, Laura, Zemlin, Michael, Wagenpfeil, Gudrun, Steffgen, Georges, Solomayer, Erich-Franz, Zemlin, Cosima, Stuhlert, Caroline, Schleicher, Julia Theresa, Wörmann, Caroline, Altmayer, Laura, Lang, Marina, Scherer, Laura-Sophie, Thul, Ida Clara, Müller, Carolin, Kaiser, Elisabeth, Stutz, Regine, Goedecke-Fritz, Sybille, Ketter, Laura, Zemlin, Michael, Wagenpfeil, Gudrun, Steffgen, Georges, and Solomayer, Erich-Franz

Abstract

Background: Moderate physical activity is associated with an improved prognosis and psychosocial outcome in breast cancer patients. Although exercise and physical activity are associated with multiple physiological and psychological effects, many of the underlying mechanisms remain obscure. The BEGYN study (Influence of physical activity in breast cancer patients on physiological and psychological parameters and on biomarkers) aims at identifying potential associations between the extent of physical activity, fitness, body composition, immunological biomarkers, psycho-emotional parameters, and the course of treatment during the first year after diagnosis of breast cancer. Methods: The prospective observational BEGYN study will include 110 non-metastatic breast cancer patients. The patients will be assessed during a base line visit prior to the initiation of the antineoplastic therapy and after 3, 6, 9 and 12 months. The physical activity will be measured using a fitness tracker and a self-assessment diary during the entire study. Each visit will include the assessment of (i) cardiorespiratory fitness measured by spiroergometry, (ii) body composition, (iii) psycho-emotional parameters (quality of life, mental health, fatigue, depression, distress, anxiety, well-being), and (iv) extensive blood tests including routine laboratory, vitamin D, selenium and immunologically relevant biomarkers (e.g., leukocyte subpopulations and cytokine profiles). Discussion: Whereas most studies investigating the influence of physical activity in breast cancer patients focus on specific activities for three months or less, the BEGYN study will quantify the daily physical activity and cardiorespiratory fitness of breast cancer patients based on objective measurements in the context of the oncological therapy for 12 months after diagnosis. The study will reveal potential associations between exercise, immune status and physical as well as psycho-emotional outcome and the clinical course of

Published
2021

8. BEGYN: Auswirkungen von Bewegung und sportlicher Aktivität bei gynäkologischen Krebspatienten auf Lebensqualität, Körperzusammensetzung und prognoserelevante Biomarker

Author

Zemlin, Cosima, Stuhlert, Caroline, Schleicher, Julia Theresa, Wörmann, Carolin, Altmayer, Laura, Lang, Marina, Scherer, Laura-Sophie, Maier, Isabelle, Kaiser, Elisabeth, Stutz, Regina, Steffgen, Georges, Solomayer, Erich-Franz, Zemlin, Cosima, Stuhlert, Caroline, Schleicher, Julia Theresa, Wörmann, Carolin, Altmayer, Laura, Lang, Marina, Scherer, Laura-Sophie, Maier, Isabelle, Kaiser, Elisabeth, Stutz, Regina, Steffgen, Georges, and Solomayer, Erich-Franz

Published
2021

9. Auswirkungen von körperlicher Aktivität auf Lebensqualität und Nebenwirkungen unter onkologischer Therapie bei nicht metastasierten Mammakarzinom Patientinnen

Author

Stuhlert, Caroline

Abstract

Ein signifikanter Einfluss von körperlicher Aktivität auf Lebensqualität, körperliche und berufliche Leistung, Schmerzen, Fatigue und eine Zunahme des Appetits konnte gezeigt werden. 52,70% der Patientinnen erreichten nach 3 Monaten das empfohlene Aktivitätslevel der WHO von 600 MET-min pro Woche, zur Messung nach 6 Monaten konnte eine Steigerung um 5,41% verzeichnet werden. Vor allem in der Gruppe der Chemotherapie Patientinnen konnte ein höheres Maß an körperlicher Aktivität festgestellt werden und eine größere Steigerung von 3,88% von der 3 zur 6-monatigen Messung. Außerdem zeigte sich bei den Chemotherapie Patientinnen ein größerer Zusammenhang ihres Bewegungsausmaßes mit mittlerer Effektstärke in Bezug auf Lebensqualität, berufliche Leistung und Appetitlosigkeit nach 3 Monaten sowie auf Schmerzen nach 6 Monaten.

Published
2023

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