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1. Dorzagliatin add-on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial

Author

Yang, Wenying, Zhu, Dalong, Gan, Shenglian, Dong, Xiaolin, Su, Junping, Li, Wenhui, Jiang, Hongwei, Zhao, Wenjuan, Yao, Minxiu, Song, Weihong, Lu, Yibing, Zhang, Xiuzhen, Li, Huifang, Wang, Guixia, Qiu, Wei, Yuan, Guoyue, Ma, Jianhua, Li, Wei, Li, Ziling, Wang, Xiaoyue, Zeng, Jiao’e, Yang, Zhou, Liu, Jingdong, Liang, Yongqian, Lu, Song, Zhang, Huili, Liu, Hui, Liu, Ping, Fan, Kuanlu, Jiang, Xiaozhen, Li, Yufeng, Su, Qing, Ning, Tao, Tan, Huiwen, An, Zhenmei, Jiang, Zhaoshun, Liu, Lijun, Zhou, Zunhai, Zhang, Qiu, Li, Xuefeng, Shan, Zhongyan, Xue, Yaoming, Mao, Hong, Shi, Lixin, Ye, Shandong, Zhang, Xiaomei, Sun, Jiao, Li, Ping, Yang, Tao, Li, Feng, Lin, Jingna, Zhang, Zhinong, Zhao, Ying, Li, Ruonan, Guo, Xiaohui, Yao, Qi, Lu, Weiping, Qu, Shen, Li, Hongmei, Tan, Liling, Wang, Wenbo, Yao, Yongli, Chen, Daoxiong, Li, Yulan, Gao, Jialin, Hu, Wen, Fei, Xiaoqiang, Wu, Tianfeng, Dong, Song, Jin, Wenlong, Li, Chenzhong, Zhao, Dong, Feng, Bo, Zhao, Yu, Zhang, Yi, Li, Xiaoying, and Chen, Li

Published
2022
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3. The DAWN study of dorzagliatin as add-on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, phase 3 trial

Author

Chen, Li, primary, Yang, Wenying, additional, Zhu, Dalong, additional, Li, Xiaoying, additional, Gan, Shenglian, additional, Dong, Xiaolin, additional, Su, Junping, additional, Li, Wenhui, additional, Jiang, Hongwei, additional, Zhao, Wenjuan, additional, Yao, Minxiu, additional, Song, Weihong, additional, Lu, Yibing, additional, Zhang, Xiuzhen, additional, Li, Huifang, additional, Wang, Guixia, additional, Qiu, Wei, additional, Yuan, Guoyue, additional, Ma, Jianhua, additional, Li, Wei, additional, Li, Ziling, additional, Wang, Xiaoyue, additional, Zeng, Jiao’e, additional, Yang, Zhou, additional, Liu, Jingdong, additional, Liang, Yongqian, additional, Lu, Song, additional, Zhang, Huili, additional, Liu, Hui, additional, Liu, Ping, additional, Fan, Kuanlu, additional, Jiang, Xiaozhen, additional, Li, Yufeng, additional, Su, Qing, additional, Ning, Tao, additional, Tan, Huiwen, additional, An, Zhenmei, additional, Jiang, Zhaoshun, additional, Liu, Lijun, additional, Zhou, Zunhai, additional, Zhang, Qiu, additional, Li, Xuefeng, additional, Shan, Zhongyan, additional, Xue, Yaoming, additional, Mao, Hong, additional, Shi, Lixin, additional, Ye, Shandong, additional, Zhang, Xiaomei, additional, Sun, Jiao, additional, Yang, Tao, additional, Li, Feng, additional, Lin, Jingna, additional, Zhang, Zhinong, additional, Zhao, Ying, additional, Li, Ruonan, additional, Guo, Xiaohui, additional, Yao, Qi, additional, Lu, Weiping, additional, Qu, Shen, additional, Li, Hongmei, additional, Tan, Liling, additional, Wang, Wenbo, additional, Yao, Yongli, additional, Chen, Daoxiong, additional, Li, Yulan, additional, Gao, Jialin, additional, Hu, Wen, additional, Fei, Xiaoqiang, additional, Wu, Tianfeng, additional, Dong, Song, additional, Jin, Wenlong, additional, Li, Chenzhong, additional, Zhao, Dong, additional, Feng, Bo, additional, Zhao, Yu, additional, and Zhang, Yi, additional

Published
2021
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8. Formate Salt as a Bifunctional Reagent for Hydroxylation and Carbonylation Reactions Under Photochemically Driven Nickel Catalysis.

Author

Yang Y, Su J, Guerin T, Nielsen M, and Tlili A

Abstract

In this study, we disclose for the first time that formate salt can be used as a bifunctional reagent for the synthesis of phenol derivatives and as a CO source for carbonylative cross-coupling processes using the COware gas reactor under activation free conditions. Key to this success is the in-situ synthesis of aryl formate via an unprecedented nickel/organophotocatalyst system under blue LED irradiation. This developed system demonstrated high applicability to various aryl iodide substrates for synthesizing phenol derivatives. Moreover, the generated CO could be utilized in a range of carbonylative C-heteroatom and C-C processes. Notably, commercially available H13COONa salt can serve as a bifunctional reagent for both synthesizing phenols and generating 13CO., (© 2024 Wiley‐VCH GmbH.)

Published
2024
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