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Keywords: behavioral inhibition; developmental pathways; ERN; irritability; psychopathology; corrigendum EN behavioral inhibition developmental pathways ERN irritability psychopathology corrigendum 1198 1200 3 08/10/22 20220801 NES 220801 The article "Developmental pathways to social anxiety and irritability: The role of ERN" (Filippi et al., 2020) included an error. A typo in one of the MATLAB scripts caused one of the seven electrodes going into the error-related negativity (ERN) ERP cluster to be from an incorrect scalp location (computing the cluster relies on indexing into a matrix and one of the indices were off by a value of 1). Similarly, after re-running all analyses in the main text and supplement using the corrected variable, we find that U all primary results involving the ERN (interactions, follow-up correlations, and partial correlation tests) remain unchanged in terms of significance. u It is worth noting that while one of the control analyses does change from I p i <.05 to I p i =.06, the associated follow-up partial correlation tests remain unchanged in terms of significance. [Extracted from the article]

Early behaviors that differentiate later biomarkers for psychopathology can guide preventive efforts while also facilitating pathophysiological research. We tested whether error-related negativity (ERN) moderates the link between early behavior and later psychopathology in two early childhood phenotypes: behavioral inhibition and irritability. From ages 2 to 7 years, children (n = 291) were assessed longitudinally for behavioral inhibition (BI) and irritability. Behavioral inhibition was assessed via maternal report and behavioral responses to novelty. Childhood irritability was assessed using the Child Behavior Checklist. At age 12, an electroencephalogram (EEG) was recorded while children performed a flanker task to measure ERN, a neural indicator of error monitoring. Clinical assessments of anxiety and irritability were conducted using questionnaires (i.e., Screen for Child Anxiety Related Disorders and Affective Reactivity Index) and clinical interviews. Error monitoring interacted with early BI and early irritability to predict later psychopathology. Among children with high BI, an enhanced ERN predicted greater social anxiety at age 12. In contrast, children with high childhood irritability and blunted ERN predicted greater irritability at age 12. This converges with previous work and provides novel insight into the specificity of pathways associated with psychopathology. [ABSTRACT FROM AUTHOR]