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5. Reflecting on a decade of progress: Zero Discrimination Day and the ongoing struggle against transphobia

Author

Cortes, Claudia P. and Sued, Omar

Subjects
Transgender people -- Civil rights -- Health aspects, Health care disparities -- Evaluation, Gender equality -- Evaluation, Health
Abstract

On 1 March 2014, the first Zero Discrimination Day was established as a call for eradicating discrimination in all forms and promoting social inclusion and tolerance. Now, 10 years later, [...]

Published
2024
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6. Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women

Author

Landovitz, Raphael J, Donnell, Deborah, Clement, Meredith E, Hanscom, Brett, Cottle, Leslie, Coelho, Lara, Cabello, Robinson, Chariyalertsak, Suwat, Dunne, Eileen F, Frank, Ian, Gallardo-Cartagena, Jorge A, Gaur, Aditya H, Gonzales, Pedro, Tran, Ha V, Hinojosa, Juan C, Kallas, Esper G, Kelley, Colleen F, Losso, Marcelo H, Madruga, J Valdez, Middelkoop, Keren, Phanuphak, Nittaya, Santos, Breno, Sued, Omar, Valencia Huamaní, Javier, Overton, Edgar T, Swaminathan, Shobha, Del Rio, Carlos, Gulick, Roy M, Richardson, Paul, Sullivan, Philip, Piwowar-Manning, Estelle, Marzinke, Mark, Hendrix, Craig, Li, Maoji, Wang, Zhe, Marrazzo, Jeanne, Daar, Eric, Asmelash, Aida, Brown, Todd T, Anderson, Peter, Eshleman, Susan H, Bryan, Marcus, Blanchette, Cheryl, Lucas, Jonathan, Psaros, Christina, Safren, Steven, Sugarman, Jeremy, Scott, Hyman, Eron, Joseph J, Fields, Sheldon D, Sista, Nirupama D, Gomez-Feliciano, Kailazarid, Jennings, Andrea, Kofron, Ryan M, Holtz, Timothy H, Shin, Katherine, Rooney, James F, Smith, Kimberly Y, Spreen, William, Margolis, David, Rinehart, Alex, Adeyeye, Adeola, Cohen, Myron S, McCauley, Marybeth, and Grinsztejn, Beatriz

Subjects
Prevention, Patient Safety, Clinical Research, Sexual and Gender Minorities (SGM/LGBT*), HIV/AIDS, Infectious Diseases, Clinical Trials and Supportive Activities, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Infection, Good Health and Well Being, Administration, Oral, Adult, Aged, Anti-HIV Agents, Delayed-Action Preparations, Double-Blind Method, Drug Administration Schedule, Drug Resistance, Female, HIV Infections, HIV Integrase Inhibitors, Homosexuality, Male, Humans, Injections, Intramuscular, Intention to Treat Analysis, Male, Medication Adherence, Middle Aged, Pre-Exposure Prophylaxis, Pyridones, Tenofovir, Transgender Persons, Young Adult, HPTN 083 Study Team, Medical and Health Sciences, General & Internal Medicine
Abstract

BackgroundSafe and effective long-acting injectable agents for preexposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) infection are needed to increase the options for preventing HIV infection.MethodsWe conducted a randomized, double-blind, double-dummy, noninferiority trial to compare long-acting injectable cabotegravir (CAB-LA, an integrase strand-transfer inhibitor [INSTI]) at a dose of 600 mg, given intramuscularly every 8 weeks, with daily oral tenofovir disoproxil fumarate-emtricitabine (TDF-FTC) for the prevention of HIV infection in at-risk cisgender men who have sex with men (MSM) and in at-risk transgender women who have sex with men. Participants were randomly assigned (1:1) to receive one of the two regimens and were followed for 153 weeks. HIV testing and safety evaluations were performed. The primary end point was incident HIV infection.ResultsThe intention-to-treat population included 4566 participants who underwent randomization; 570 (12.5%) identified as transgender women, and the median age was 26 years (interquartile range, 22 to 32). The trial was stopped early for efficacy on review of the results of the first preplanned interim end-point analysis. Among 1698 participants from the United States, 845 (49.8%) identified as Black. Incident HIV infection occurred in 52 participants: 13 in the cabotegravir group (incidence, 0.41 per 100 person-years) and 39 in the TDF-FTC group (incidence, 1.22 per 100 person-years) (hazard ratio, 0.34; 95% confidence interval, 0.18 to 0.62). The effect was consistent across prespecified subgroups. Injection-site reactions were reported in 81.4% of the participants in the cabotegravir group and in 31.3% of those in the TDF-FTC group. In the participants in whom HIV infection was diagnosed after exposure to CAB-LA, INSTI resistance and delays in the detection of HIV infection were noted. No safety concerns were identified.ConclusionsCAB-LA was superior to daily oral TDF-FTC in preventing HIV infection among MSM and transgender women. Strategies are needed to prevent INSTI resistance in cases of CAB-LA PrEP failure. (Funded by the National Institute of Allergy and Infectious Diseases and others; HPTN 083 ClinicalTrials.gov number, NCT02720094.).

Published
2021

7. Efficacy and safety of long-acting cabotegravir compared with daily oral tenofovir disoproxil fumarate plus emtricitabine to prevent HIV infection in cisgender men and transgender women who have sex with men 1 year after study unblinding: a secondary analysis of the phase 2b and 3 HPTN 083 randomised controlled trial

Author

Landovitz, Raphael J, Hanscom, Brett S, Clement, Meredith E, Tran, Ha V, Kallas, Esper G, Magnus, Manya, Sued, Omar, Sanchez, Jorge, Scott, Hyman, Eron, Joe J, del Rio, Carlos, Fields, Sheldon D, Marzinke, Mark A, Eshleman, Susan H, Donnell, Deborah, Spinelli, Matthew A, Kofron, Ryan M, Berman, Richard, Piwowar-Manning, Estelle M, Richardson, Paul A, Sullivan, Philip A, Lucas, Jonathan P, Anderson, Peter L, Hendrix, Craig W, Adeyeye, Adeola, Rooney, James F, Rinehart, Alex R, Cohen, Myron S, McCauley, Marybeth, and Grinsztejn, Beatriz

Published
2023
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10. Immunological and virological findings in a patient with exceptional post-treatment control: a case report

Author

Nicolás, David, Xufré, Cristina, Hurtado, Carmen, Rovira, Cristina, Sued, Omar, Brunet, Mercé, López-Diéguez, María, Manzardo, Christian, Agüero, Fernando, Tuset, Montserrat, Guardo, Alberto C, Marcos, Maria A., del Mar Mosquera, María, Muñoz-Fernández, M. Ángeles, Caballero, Miguel, Ligero, Carmen, Fernández, Emma, Marcos, M. Ángeles, Gatell, José M, de Lazzari, Elisa, Gallart, Teresa, Fernandez-Tenreiro, Ana, Gomez, Begoña, Berrocal, Leire, Mosquera, María del Mar, Climent, Núria, Ambrosioni, Juan, González, Tània, Casadellà, Maria, Noguera-Julian, Marc, Paredes, Roger, Plana, Montserrat, Grau-Expósito, Judith, Mallolas, Josep, Alcamí, José, Sánchez-Palomino, Sonsoles, and Miró, José M

Published
2023
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17. Final efficacy analysis, interim safety analysis, and immunogenicity of a single dose of recombinant novel coronavirus vaccine (adenovirus type 5 vector) in adults 18 years and older: an international, multicentre, randomised, double-blinded, placebo-controlled phase 3 trial

Author

Mao, Helen, Gagnon, Luc, Tran, Steven-Phay, Khan, Sarwat Tahsin, Becerra Aquino, Amalia Guadalupe, Saldaña Montemayor, Edgar Eduardo, Rivera Martínez, Norma Eréndira, Bohórquez López, Víctor Casildo, Simón Campos, J. Abraham, Pineda Cárdenas, Felipe de Jesús, Chen, Wei, Hou, Lihua, Zhang, Zhe, Corral, Gonzalo, López, Eduardo, Teijeiro, Ricardo, Alzogaray, Maria F., Zaidman, Cesar, Lopardo, Gustavo, Goecke, Bernardo, Feijooó Seoane, Rosa María, Mahmood, Sayed Faisal, Khan, Ejaz Ahmed, Akram, Jayed, Abbas, Salma, Salahuddin, Naseem, Rozhkova, Elena, Zubkova, Tatyana, Halperin, Scott A, Ye, Lingyun, MacKinnon-Cameron, Donna, Smith, Bruce, Cahn, Pedro E, Ruiz-Palacios, Guillermo M, Ikram, Aamer, Lanas, Fernando, Lourdes Guerrero, M, Muñoz Navarro, Sergio Raúl, Sued, Omar, Lioznov, Dmitry A, Dzutseva, Vitalina, Parveen, Ghazala, Zhu, Fengcai, Leppan, Laura, Langley, Joanne M, Barreto, Luis, Gou, Jinbo, and Zhu, Tao

Published
2022
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18. Impact of the Introduction of a Package of Care Involving Early Detection of Opportunistic Infections in People Living with HIV/AIDS: A Pan American Health Organization (PAHO) Initiative in Brazil

Author

Pasqualotto, Alessandro C., primary, Sued, Omar, additional, Reis, Nicole, additional, Silva, Larissa R., additional, Soares, Renata B. A., additional, Godoy, Cassia S. M., additional, Melo, Marineide G., additional, Hatem, Nayla A., additional, Razzolini, Bruna Regis, additional, Noal, Andressa, additional, Vieceli, Tarsila, additional, Falci, Diego R., additional, and Perez, Freddy, additional

Published
2024
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21. Overview of SARS-CoV-2 infection in adults living with HIV

Author

Ambrosioni, Juan, Blanco, Jose L., de la Mora, Lorena, Garcia-Alcaide, Felipe, González-Cordón, Ana, Inciarte, Alexis, Laguno, Montserrat, Leal, Lorna, Martínez-Chamorro, Esteban, Martínez-Rebollar, María, Miró, José M, Rojas, Jhon F., Torres, Berta, Mallolas, Josep, Albiac, Laia, Agöero, Daiana L., Bodro, Marta, Cardozo, Celia, Chumbita, Mariana, García, Nicol, García-Vidal, Carolina, Hernández-Meneses, Marta M., Herrera, Sabina, Linares, Laura, Moreno, Antonio, Morata, Laura, Martínez-Martínez, Jose A., Puerta, Pedro, Rico, Verónica, Soriano, Alex, Martínez, Mikel, Mosquera, María del Mar, Marcos, Maria A., Vila, Jordi, Tuset, Montse, Soy, Dolors, Vilella, Anna, Almuedo, Alex, Pinazo, María J., Muñoz, Jose, Blanco, José Luis, Reyes-Urueña, Juliana M, Davies, Mary-Ann, Sued, Omar, Marcos, Maria Angeles, Martínez, Esteban, Bertagnolio, Silvia, Alcamí, Jose, and Miro, Jose M

Published
2021
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23. RBD-specific polyclonal F(ab´)2 fragments of equine antibodies in patients with moderate to severe COVID-19 disease: A randomized, multicenter, double-blind, placebo-controlled, adaptive phase 2/3 clinical trial

Author

Lopardo, Gustavo, Belloso, Waldo H., Nannini, Esteban, Colonna, Mariana, Sanguineti, Santiago, Zylberman, Vanesa, Muñoz, Luciana, Dobarro, Martín, Lebersztein, Gabriel, Farina, Javier, Vidiella, Gabriela, Bertetti, Anselmo, Crudo, Favio, Alzogaray, Maria Fernanda, Barcelona, Laura, Teijeiro, Ricardo, Lambert, Sandra, Scublinsky, Darío, Iacono, Marisa, Stanek, Vanina, Solari, Rubén, Cruz, Pablo, Casas, Marcelo Martín, Abusamra, Lorena, Luciardi, Héctor Lucas, Cremona, Alberto, Caruso, Diego, de Miguel, Bernardo, Lloret, Santiago Perez, Millán, Susana, Kilstein, Yael, Pereiro, Ana, Sued, Omar, Cahn, Pedro, Spatz, Linus, and Goldbaum, Fernando

Published
2021
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24. Immune variations throughout the course of tuberculosis treatment and its relationship with adrenal hormone changes in HIV-1 patients co-infected with Mycobacterium tuberculosis

Author

Vecchione, María Belén, Angerami, Matías Tomás, Suarez, Guadalupe Verónica, Turk, Gabriela, Laufer, Natalia, Ben, Graciela, Ameri, Diego, Gonzalez, Diego, Parodi, Laura M., Giavedoni, Luis D., Maidana, Patricia, Fabre, Bibiana, Mesch, Viviana, Sued, Omar, and Quiroga, Maria Florencia

Published
2021
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26. Cumulative Burden of Mental Health Factors and Engagement in HIV Care in Argentina

Author

Sued, Omar, Cecchini, Diego, Abbamonte, John M., Rodriguez, Violeta J., Mandell, Lissa N., Cristofari, Nicholas V., Figueroa, Maria Inés, Cassetti, Isabel, Cahn, Pedro, Weiss, Stephen M., Alcaide, Maria L., Cahn, Florencia, Calanni, Liliana, Crinejo, Ana, David, Daniel, Lupo, Sergio, Pérez, Carolina, Pérez, Rufina, Rodriguez, Claudia, Rolón, María José, Sisto, Alicia, Trapé, Liliana, and Jones, Deborah L.

Published
2021
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27. Service delivery challenges in HIV care during the first year of the COVID‐19 pandemic: results from a site assessment survey across the global IeDEA consortium

Author

Brazier, Ellen, Ajeh, Rogers, Maruri, Fernanda, Musick, Beverly, Freeman, Aimee, Wester, C. William, Lee, Man?Po, Shamu, Tinei, Ramírez, Brenda Crabtree, D' Almeida, Marcelline, Wools?Kaloustian, Kara, Kumarasamy, N., Althoff, Keri N., Twizere, Christella, Grinsztejn, Beatriz, Tanser, Frank, Messou, Eugène, Byakwaga, Helen, Duda, Stephany N., Nash, Denis, Chansilpa, Chidchon, Dougherty, Trevor, Karminia, Azar, Law, Matthew, Ross, Jeremy, Sohn, Annette, Aguirre, Ivette, Baker, David, Bloch, Mark, Cabot, Safaa, Carr, Andrew, Couldwell, Deborah, Edwards, Sian, Eu, Beng, Farlow, Heather, Finlayson, Robert, Gunathilake, Manoji, Hazlewood, Cherie, Hoy, Jennifer, Langton?Lockton, Julian, Le, Jacqueline, Leprince, Elizabeth, Minc, Ariane, Moore, Richard, O'Sullivan, Maree, Roth, Norm, Rowling, Dianne, Russell, Darren, Ryder, Nathan, Saunders, Craig, Silvers, Julie, Smith, David J., Sowden, David, Sweeney, Grant, Tan, Lynn, Teague, Ricard, Templeton, David, Thng, Caroline, Woolley, Ian, Khol, Vohith, Ly, Penh Sun, Li, Tsz Hei, Po, Lee Man, Kinikar, Aarti, Kumarasamy, Nagalingeswaran, Mundhe, Sanjay, Pujari, Sanjay, Sangle, Shashikala, Nimkar, Smita, Jassin, Madelein, Kurniati, Nia, Merati, Tuti Parwati, Muktiarti, Dina, Amalia, Rizqi, Sukmawati, Ni Made Dewi Dian, Wati, Ketut Dewi Kumara, Yunihastuti, Evy, Tanuma, Junko, Choi, Jun Yong, Azwa, Raja Iskandar Shah Raja, Cheng, Chan Kwai, Gani, Yasmin Mohamed, Mohamed, Thahira Jamal, Moy, Fong Siew, Nallusamy, Revathy, Nor, Mohamad Zulfahami Mohd, Rudi, Nuraini, Shyan, Wong Peng, Yusoff, Nik Khairulddin Nik, Ditangco, Rossana, Chan, Yu?Jiun, Wu, Pei?Chieh, Wu, Ping?Feng, Avihingsanon, Anchalee, Chaiwarith, Romanee, Chokephaibulkit, Kulkanya, Khusuwan, Suwimon, Kiertiburanakul, Sasisopin, Kosalaraksa, Pope, Lumbiganon, Pagakrong, Ounchanam, Pradtana, Puthanakit, Thanyawee, Rungmaitree, Supattra, Solai, Nuttarika, Sudjaritruk, Tavitiya, An, Vu Thien, Cuong, Do Duy, Do, Chau Viet, Huy, Bui Vu, Quy, Tuan, Van Nguyen, Kinh, Nguyen, Luan, Nguyen, Van Lam, Nguyen, Yen Thi, Nong, Vuong Minh, Truong, Huu Khanh, Tuyen, Ngo Thi Thu, Mcgowan, Catherine C., Duda, Stephany, Cahn, Florencia, Cahn, Pedro, Cesar, Carina, Fink, Valeria, Sued, Omar, Coelho, Lara, Machado, Daisy Maria, Pinto, Jorge, Wolff, Marcelo, Rouzier, Vanessa, Padgett, Denis, Gotuzzo, Eduardo, Biziragusenyuka, Jérémie, Gateretse, Patrick, Nimbona, Pelagie, Niyonkuru, Olive, Twizere, Christelle, Anicetus, Surreng, Djenabou, Amadou, Enow, Priscilla, Mbu, Eyongetah, Manga, Martin, Ndobe, Mercy, Nasah, Judith, Ekossono, Elle Nathalie Syntyche, Bouseko, Mireille Teno, Kitetele, Faustin, Lelo, Patricia, Diafouka, Merlin Isidore Justin, Mafoua, Adolphe, Nsonde, Dominique Mahambou, Bihira, Uitonze Aime Maurice, Dusabe, Marie Chantal, Feza, Rosine, Habanabashaka, Jean Claude, Habumuremyi, Viateur, Igizeneza, Ernestine, Kamigisha, Anne Marie, Kubwimana, Gallican, Maniriho, Gilbert, Mbaraga, Gilbert, Muhoza, Benjamin, Mukakarangwa, Jeanne, Mukamana, Joyce, Mukanyirigira, Patricie, Mukeshimana, Yvone Claude, Munyaneza, Athanase, Murenzi, Gad, Musaninyange, Jacqueline, Nyiraneza, Jules Ndumuhire, Ntarambirwa, Fidele, Nyiraneza, Marie Louise, Tuyishime, Josette, Tuyishimire, Yvonne, Ubandutira, Alexis, Umugiraneza, Florance, Umugwaneza, Rosine, Uwamahoro, Olive, Uwamahoro, Pauline, Uwambaje, Marie Victoire, Uwimpuhwe, Clarisse, Uwiragiye, Siphora, Kuhn, Yee Yee, Adera, Felix, Adhiambo, Beatricec, Aggrey, Khaemba, Akadikor, Daniel, Ambulla, Felix, Apiyo, Dorah, Ariya, Patrick, Atemba, Naftal, Ayodi, Fridah, Benard, Chirchir, Bett, Maureen, Birgen, Serafine, Bwalei, Rael, Chebon, Nancy, Chebor, Valentine Jirry, Chebuiywo, Philip, Chemutai, Jacline, Chepkorir, Emily, Chepseba, Carolyne, Chirchir, John, Diero, Lameck, Dukwa, Benard, Elphas, Alice, Etyang, Tom, Idiama, Agnes, Jebichuko, Ann, Jepchumba, Delvine, Juma, Churchill, Juma, Maureen, Juma, Sheila, Kadima, Julie, Karani, Rose, Keitany, Christopher, Keter, Pricilla, Kiavoga, Lucy, Kibet, Harrison, Kimutai, Ruth, Kiplagat, Mutai, Kiprono, Wilfred, Kipruto, Nicholas Kogei, Kirimi, Asenath, Koech, Zeddy, Kosgei, Carolyne, Kutto, Karen, Kweyu, Mildred, Liech, Ephraim Kenneth, Limo, Milka, Maina, Rose, Marumbu, Priscah, Masese, Agnes, Mochotto, Patricia, Molly, Omudeck, Momanyi, Tom, Murutu, John W., Mwanda, Praxidis, Ndakalu, Lillian, Nderitu, Rose N., Obatsa, Sarah, Obiga, Fredrick, Oboya, Moses, Odhiambo, Joseph, Olaya, George, Omanyala, Oscar, Oray, Christine, Otieno, Molly, Otwane, Modesta Toto, Ouma, Paul, Owuor, Charles, Pepela, Doris Tutu, Pessah, Collins, Rotich, Evans, Rotich, Edwin K., Rutto, Titus C., Shikuku, Monica, Sibweche, Rose Naliaka, Simiyu, Robert Wanyonyi, Siria, Hellen, Some, Michael, Songok, Winnie Cherotich, Tanui, Immaculate, Wafula, Grace, Wambura, Rebecca, Wanjala, Ellah, Wanyama, Carolyne, Wanyonyi, Hellen, Woyakapel, Emmanuel, Zelbabel, Wandera, Gwimo, Dikengela, Kinyota, Ester, Lwali, Jerome, Lyamuya, Rita, Machemba, Richard, Mathias, Julia, Mkombachepa, Lilian, Mokiwa, Athuman, Mushi, Ombeni, Ndunguru, Charles, Ngonyani, Kapella, Nyaga, Charles, Ruta, Happiness, Urassa, Mark, Akanyihayo, James, Arinaitwe, Arnold, Batuuka, Jesca, Birungi, Walusimbi, Bugembe, John Nyanzi, Ddungu, Ahmed, Francis, Kato, Imran, Bangira, Kafuuma, George William, Kalulue, John Bosco, Kanaabi, Grace, Kanyesigye, Michale, Karuhanga, Godfery, Kasozi, Charles, Kasule, Godfrey, Katusime, Assumpta, Kibalama, Donozio, Kimera, Simon Peter, Kulusumu, Namatovu, Lule, Yusuf, Lwanga, Isaac, Mluindwa, Margaret, Moses, Jemba, Mubarak, Sseremba, Muggaga, Daniel, Mukalazi, Evelyn, Muleebwa, Joseph, Mulema, Derick, Musisi, Ivan, Muwawu, John, Muyindike, Winnie, Mwaka, Dick, Naava, Milly, Nabiyki, Immaculate, Nabusulwa, Agnes, Nakabugo, Dorah, Nakamya, Esther, Nakanwagi, Daisy, Nakato, Oliver, Nakayi, Lydian, Nakigozi, Patience, Nakku, Juliet, Nakuya, Juliet, Nakyomu, Justine, Namayanja, Joan, Namirembe, Sarah, Namugumya, Juliet, Namukasa, Ezereth, Namulindwa, Viola, Nankya, Irene, Nannyondo, Grace Mugagga, Nansamba, Harriet, Nansera, Denis, Nanyanzi, Brenda, Nanyonjo, Esther Celina, Nayiga, Irene, Opira, Isaac, Owarwo, Noela C., Resty, Sserunkuma, Semuwemba, Haruna, Senoga, Julius, Sseguya, Gerald, Ssekyewa, John Paul, Ssemakadde, Matthew, Tebajjwa, Jonah, Tugumisirize, Doreen, Tushemerirwe, Robinah, Waliyi, Kawuki, Althoff, Keri, Bishop, Jennifer, Gill, M J., Loutfy, Mona, Smith, Graham, Bamford, Laura, Black, Anthony, Brice, Asia, Brown, Sheldon, Colasanti, Jonathan, Duarte, Piper, Firnhaber, Cynthia, Goetz, Matthew, Grasso, Chris, Gripshover, Barbara, Horberg, Michael, Kelly, Rita, Levine, Ken, Luu, Mitchell, Marconi, Vincent, Maroney, Karen, Mayer, Kenneth, Mayor, Angel, Mcgowan, Catherine, Multani, Ami, Napravnik, Sonia, Nijhawan, Ank, Novak, Richard, Palella, Frank, Rodriguez, Maria C., Scott, Mia, Tedaldi, Ellen, Willig, James, Cornell, Morna, Davies, Mary?Ann, Egger, Matthias, Haas, Andreas, Bereng, Monkoe, Kalake, Maleshoane, Lenela, Keketso, Seretse, Relebohile, Chintenga, Matthews, Chiwoko, Jane, Gumulira, Joe, Huwa, Jacqueline, Maluwa, Rafique, Matanje, Beatrice, Mbewe, Ronald, Mfungwe, Sunshine, Mphande, Zakaliah, Tweya, Hannock, Rafael, Idiovino, Apolles, Patti, Beneke, Eunice, Dlamini, Siphephelo, Edson, Claire, Eley, Brian, Euvrard, Jonathan, Fatti, Geoffrey, Goeieman, Bridgette, Grimwood, Ashraf, Huang, David, Hugo, Susan, Ismail, Zahiera, Jennings, Lauren, Mathenjwa, Thulile, Monteith, Lizette, Mshweshwe, Zamuxolo, Ntuli, Mfundi, Ndlovu, En, Ndlozi, Hloniphile, Noyakaza, Sylvia, Prozesky, Hans, Rabie, Helena, Sipambo, Nosisa, Technau, Karl?Günter, Tembe, Thokozani, Xaba, Nontando, Njobvu, Thandiwe, Munthaly, Mary, Mwetwa, Elly, Kabeba, Gillian, Mwendafilumba, Derrick, Maanguka, Ethel, Manyika, Nelly, Mwansa, Chalwe, Banda, Future, Mwenda, Dickson, Bwalya, Abel, Shapi, Leah, Syame, Kasapo, Sashi, Rita, Mulenga, Chisha, Nanyangwe, Ruth, Chimbetete, Cleophas, Chinofunga, A., Mhike, J., Mubvigwi, E., Nyika, F., Quarter, Kumbirai Pise, Arikawa, Shino Chassagne, Becquet, Renaud, Bernard, Charlotte, Dabis, François, Desmonde, Sophie, Dahourou, Désiré, Ekouevi, Didier Koumavi, Jaquet, Antoine, Jesson, Julie, Leroy, Valeriane, Malateste, Karen, Rabourdin, Elodie, Tiendrebeogo, Thierry, Assogba, Michée, Zannou, Djimon Marcel, Hounhoui, Ghislaine, Bere, Denise, Poda, Armel, Pooda, Gbolo, Traore, Richard, Abauble, Yao, Abby, Ouattara, Acquah, Patrick, Andoble, Valérie, Aude, Yobo N'Dzama, Azani, Jean?Claude, Berete, Oka, Beugre, Jacques Daple, Bohoussou, Caroline Yao, Brou, Simon Boni Emmanuel, Chenal, Henri, Cissé, Abdoulaye, Coulibaly, Nambate, Dainguy, Marie Evelyne, Daligou, Marcelle, D' Aquin, Toni Thomas, Dasse, Claude Desire, Folquet, Madeleine Amorissani, Gnepa, Guy, Gobe, Olivier, Guira, Salif, Hawerlander, Denise, Horo, Apollinaire, Kanga, Guillaume, Messou, Zobo Konan Eugène, Minga, Kla Albert, Moh, Raoul, N'Gbeche, Mariesylvie, Ogbo, Patricia, Oulai, Mathieu, Stéphanie, Se, Eboua, Tanoh, Valère, Itchy Max, Afrane, Adwoa Kumiwa Asare, Akrofi, Esther, Andoh, John Christian, Renner, Lorna, Bagayoko, Awa, Bagayoko, Kadidiatou, Bah, Abdou Salam, Berthe, Alima, Coulibaly, Boureïma, Coulibaly, Fatimata, Coulibaly, Yacouba Aba, Diakité, Aïssata, Bocoum, Fatoumata, Boré, Fatoumata, Dicko, Fatoumata, Koné, Odile, Sylla, Mariam, Tangara, Assitan, Traoré, Mamadou, Seydi, Moussa, Amegatse, Edmond, Djossou, Julienne, Takassi, Elom, and Palanga, Sénam

Subjects
HIV (Viruses) -- Care and treatment -- Patient outcomes, Public health administration -- Evaluation, Health
Abstract

: Introduction: Interruptions in treatment pose risks for people with HIV (PWH) and threaten progress in ending the HIV epidemic; however, the COVID‐19 pandemic's impact on HIV service delivery across diverse settings is not broadly documented. Methods: From September 2020 to March 2021, the International epidemiology Databases to Evaluate AIDS (IeDEA) research consortium surveyed 238 HIV care sites across seven geographic regions to document constraints in HIV service delivery during the first year of the pandemic and strategies for ensuring care continuity for PWH. Descriptive statistics were stratified by national HIV prevalence ( Results: Questions about pandemic‐related consequences for HIV care were completed by 225 (95%) sites in 42 countries with low (n = 82), medium (n = 86) and high (n = 57) HIV prevalence, including low‐ (n = 57), lower‐middle (n = 79), upper‐middle (n = 39) and high‐ (n = 50) income countries. Most sites reported being subject to pandemic‐related restrictions on travel, service provision or other operations (75%), and experiencing negative impacts (76%) on clinic operations, including decreased hours/days, reduced provider availability, clinic reconfiguration for COVID‐19 services, record‐keeping interruptions and suspension of partner support. Almost all sites in low‐prevalence and high‐income countries reported increased use of telemedicine (85% and 100%, respectively), compared with less than half of sites in high‐prevalence and lower‐income settings. Few sites in high‐prevalence settings (2%) reported suspending antiretroviral therapy (ART) clinic services, and many reported adopting mitigation strategies to support adherence, including multi‐month dispensing of ART (95%) and designating community ART pick‐up points (44%). While few sites (5%) reported stockouts of first‐line ART regimens, 10–11% reported stockouts of second‐ and third‐line regimens, respectively, primarily in high‐prevalence and lower‐income settings. Interruptions in HIV viral load (VL) testing included suspension of testing (22%), longer turnaround times (41%) and supply/reagent stockouts (22%), but did not differ across settings. Conclusions: While many sites in high HIV prevalence settings and lower‐income countries reported introducing or expanding measures to support treatment adherence and continuity of care, the COVID‐19 pandemic resulted in disruptions to VL testing and ART supply chains that may negatively affect the quality of HIV care in these settings., INTRODUCTION The COVID‐19 pandemic has had major direct and indirect impacts on population health globally, through disruptions in the accessibility and quality of basic health services [1], in supply chains [...]

Published
2022
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30. Translating evidence into global impact: lessons for HIV research and policy development from the AMBITION trial

Author

Jarvis, Joseph N, primary, Chou, Roger, additional, Harrison, Thomas S, additional, Lawrence, David S, additional, Muthoga, Charles, additional, Mupeli, Kennedy, additional, Meya, David B, additional, Mwandumba, Henry C, additional, Kanyama, Cecilia, additional, Meintjes, Graeme, additional, Leeme, Tshepo B, additional, Ndhlovu, Chiratidzo E, additional, Beattie, Pauline, additional, Sued, Omar, additional, Pérez Casas, Carmen, additional, Makanga, Michael, additional, and Ford, Nathan, additional

Published
2023
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32. Obstáculos a la adherencia y retención en los sistemas de salud público y privado según pacientes y personal de salud

Author

Arístegui, Inés, primary, Dorigo, Analía, additional, Bofill, Lina, additional, Bordatto, Alejandra, additional, Lucas, Mar, additional, Fernández Cabanillas, Graciela, additional, Sued, Omar, additional, Cahn, Pedro, additional, Cassetti, Isabel, additional, Weiss, Stephen, additional, and Jones, Deborah, additional

Published
2023
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34. USO DE TESTES RÁPIDOS PARA DETERMINAR A PREVALÊNCIA DE HISTOPLASMOSE, CRIPTOCOCOSE E TUBERCULOSE EM PESSOAS VIVENDO COM HIV EM CINCO HOSPITAIS DO BRASIL - RESULTADOS PRELIMINARES

Author

da Silva, Larissa Rocha, primary, Reis, Nicole, additional, Sued, Omar Gustavo, additional, Godoy, Cassia Silva Miranda, additional, de Melo, Marineide Gonçalves, additional, Soares, Renata de Bastos Ascenço, additional, Razzolini, Bruna Regis, additional, Fonseca, Pedro Moreno, additional, Hatem, Nayla Azanki, additional, Vieceli, Tarsila, additional, Falci, Diego Rodrigues, additional, Pasqualotto, Alessandro Comarú, additional, and Perez, Freddy Mauricio, additional

Published
2023
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36. The HIV epidemic in Latin America: a time to reflect on the history of success and the challenges ahead

Author

Crabtree-Ramirez, Brenda, Belaunzaran-Zamudio, Pablo F., Cortes, Claudia P., Morales, Miguel, Sued, Omar, Sierra-Madero, Juan, Cahn, Pedro, Pozniak, Anton, and Grinsztejn, Beatriz

Subjects
Transgender people -- Health aspects, HIV tests -- Health aspects, HIV -- Health aspects, Sex oriented businesses -- Health aspects, Health, United Nations, International Organization for Migration
Abstract

Keywords: Latin America; HIV epidemic; migration; HIV; PrEP in Latin America; ART; HIV testing, According to Joint United Nations Programme on HIV/AIDS (UNAIDS) data, 1,900,000 adults and children were living with HIV in Latin America and the Caribbean in 2018 [1], where overall prevalence [...]

Published
2020
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37. Cost-effectiveness evaluation of routine histoplasmosis screening among people living with advanced HIV disease in Latin America and the Caribbean

Author

Rajasingham, Radha, primary, Medina, Narda, additional, Mousquer, Gabriel T., additional, Caceres, Diego H., additional, Jordan, Alexander, additional, Nacher, Mathieu, additional, Falci, Diego R., additional, Sebro, Ayanna, additional, Pasqualotto, Alessandro C., additional, Sued, Omar, additional, Chiller, Tom, additional, and Perez, Freddy, additional

Published
2023
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42. Retention among transgender women treated with dolutegravir associated with tenofovir/lamivudine or emtricitabine in Argentina: TransViiV study

Author

Frola, Claudia E., primary, Aristegui, Inés, additional, Figueroa, María I., additional, Radusky, Pablo D., additional, Cardozo, Nadir, additional, Zalazar, Virginia, additional, Cesar, Carina, additional, Patterson, Patricia, additional, Fink, Valeria, additional, Gun, Ana, additional, Cahn, Pedro, additional, and Sued, Omar, additional

Published
2023
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43. Immunological and virological findings in a patient with exceptional post-treatment control: a case report

Author

Climent, Núria, primary, Ambrosioni, Juan, additional, González, Tània, additional, Xufré, Cristina, additional, Casadellà, Maria, additional, Noguera-Julian, Marc, additional, Paredes, Roger, additional, Plana, Montserrat, additional, Grau-Expósito, Judith, additional, Mallolas, Josep, additional, Alcamí, José, additional, Sánchez-Palomino, Sonsoles, additional, Miró, José M, additional, Nicolás, David, additional, Hurtado, Carmen, additional, Rovira, Cristina, additional, Sued, Omar, additional, Brunet, Mercé, additional, López-Diéguez, María, additional, Manzardo, Christian, additional, Agüero, Fernando, additional, Tuset, Montserrat, additional, Guardo, Alberto C, additional, Marcos, Maria A., additional, del Mar Mosquera, María, additional, Muñoz-Fernández, M. Ángeles, additional, Caballero, Miguel, additional, Ligero, Carmen, additional, Fernández, Emma, additional, Marcos, M. Ángeles, additional, Gatell, José M, additional, de Lazzari, Elisa, additional, Gallart, Teresa, additional, Fernandez-Tenreiro, Ana, additional, Gomez, Begoña, additional, Berrocal, Leire, additional, and Mosquera, María del Mar, additional

Published
2023
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44. Correction to: Cumulative Burden of Mental Health Factors and Engagement in HIV Care in Argentina

Author

Sued, Omar, Cecchini, Diego, Abbamonte, John M., Rodriguez, Violeta J., Mandell, Lissa N., Cristofari, Nicholas V., Figueroa, Maria Inés, Cassetti, Isabel, Cahn, Pedro, Weiss, Stephen M., Alcaide, Maria L., Cahn, Florencia, Calanni, Liliana, Crinejo, Ana, David, Daniel, Lupo, Sergio, Pérez, Carolina, Pérez, Rufina, Rodriguez, Claudia, Rolón, María José, Sisto, Alicia, Trapé, Liliana, and Jones, Deborah L.

Published
2021
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48. ANÁLISIS COMPARATIVO DE LAS CARACTERÍSTICAS CLÍNICAS, EVOLUCIÓN Y MORTALIDAD DE PACIENTES HOSPITALIZADOS POR COVID-19 DURANTE LA PRIMERA Y SEGUNDA OLA DE LA PANDEMIA (REGISTRO ECCOVID).

Author

CÓRDOVA, EZEQUIEL, MYKIETIUK, ANALIA, DE VEDIA, LAUTARO, BACELAR, BRENDA, FLORENCIA CÁCERES, MARÍA, NEMIROVSKY, CORINA, CONTRERAS, ROSA, FERNANDA ALZOGARAY, MARIA, NANNINI, ESTEBAN, FERNANDA CONSALVO, MARÍA, SOLER PUY, LUCRECIA, SCAPELLATO, PABLO G., BARCELONA, LAURA, GOLIKOW, MARIANA L., FLORENCIA PIÑEIRO, MARÍA, MIÑO, HUGO J., CABRAL, MYRNA, LAMPONI TAPPATA, LUCÍA, LOPARDO, GUSTAVO, and SUED, OMAR

Abstract

Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023

49. Mental health, substance use, experiences of violence, and access to health care among transgender and non-binary people during the COVID-19 lockdown in Argentina.

Author

Radusky, Pablo D., Cardozo, Nadir, Duarte, Mariana, Fabian, Solange, Frontini, Emilia, Sued, Omar, and Aristegui, Ines

Subjects
COVID-19, SUBSTANCE abuse, HEALTH services accessibility, FOCUS groups, HORMONE therapy, NONBINARY people, VIOLENCE, DOMESTIC violence, SOCIOECONOMIC factors, SUICIDAL ideation, INCOME, PSYCHOSOCIAL factors, DESCRIPTIVE statistics, EMPLOYMENT, STAY-at-home orders, DATA analysis software, COVID-19 pandemic, TRANSGENDER people, PSYCHOLOGICAL distress, MENTAL health services, EDUCATIONAL attainment
Abstract

Background: Lockdown measures are effective to control COVID-19 spread; however, concerns have increased regarding its impact on transgender and non-binary people. Aims: This study describes self-reported changes in mental health, substance use, experiences of violence, and access to health care and basic services among transgender and non-binary population from Argentina after two months of implementation of the lockdown. Methods: An online national survey was responded by 182 participants (72 transfeminine [TF], 66 transmasculine [TM], 44 non-binary [NB] people) between May and June 2020. The questionnaire was informed by the results of focus groups, reviewed by activists, and disseminated through social media. Descriptive statistics were used to summarize data. Results: The COVID-19 pandemic and the lockdown have had a general negative impact on the participants. TF participants reported a greater proportion of negative changes in the socioeconomic aspect, such as reduction in income and barriers to access basic services (housing, food, hygiene products and financial assistance). TM and NB participants reported higher proportions of adverse psychological impact, with high frequencies of intense negative emotions and suicidal ideation. A general reduction in substance use was observed in the three groups. The most frequent source of violence in the three groups was from a family member, especially among NB participants. Half of the TF and TM individuals reported difficulties to access or continue their hormone therapy. TM and NB participants reported considerable barriers to access mental health care. Conclusion: The COVID-19 pandemic and the prolonged lockdown have had a negative impact on the transgender and NB population, aggravating their preexisting situation of vulnerability and exclusion. Furthermore, this impact affected each subgroup differently in a particular and specific way. [ABSTRACT FROM AUTHOR]

Published
2023
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