349 results on '"Sugimoto, Hachiro"'
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2. Development of dual targeting inhibitors against aggregations of amyloid-β and tau protein
3. Highly water pressurized brown rice improves cognitive dysfunction in senescence-accelerated mouse prone 8 and reduces amyloid beta in the brain
4. The New Generation of Acetylcholinesterase Inhibitors
5. Glutathione Biosynthesis via Activation of the Nuclear Factor E2–Related Factor 2 (Nrf2) – Antioxidant-Response Element (ARE) Pathway Is Essential for Neuroprotective Effects of Sulforaphane and 6-(Methylsulfinyl) Hexyl Isothiocyanate
6. Therapeutic effect of a novel curcumin derivative GT863 on a mouse model of amyotrophic lateral sclerosis
7. Therapeutic effect of a novel curcumin derivative GT863 on a mouse model of amyotrophic lateral sclerosis.
8. Mechanisms of Chronic Nicotine Treatment–Induced Enhancement of the Sensitivity of Cortical Neurons to the Neuroprotective Effect of Donepezil in Cortical Neurons
9. Serofendic Acid Promotes Stellation Induced by cAMP and cGMP Analogs in Cultured Cortical Astrocytes
10. Mechanisms of α7-nicotinic receptor up-regulation and sensitization to donepezil induced by chronic donepezil treatment
11. Protective effect of serofendic acid on ischemic injury induced by occlusion of the middle cerebral artery in rats
12. Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe/PS1dE9 mouse model of Alzheimer's disease
13. Serofendic acid protects from iodinated contrast medium and high glucose probably against superoxide production in LLC-PK1 cells
14. Synthesis and pharmacological profile of serofendic acids A and B
15. Donepezil Potentiates Nerve Growth Factor-Induced Neurite Outgrowth in PC12 Cells
16. Aromatherapy improves cognitive dysfunction in senescence-accelerated mouse prone 8 by reducing the level of amyloid beta and tau phosphorylation
17. Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis)
18. Anti-arthritic effect of E3 ubiquitin ligase, c-MIR, expression in the joints
19. Development of a brain-permeable peptide nanofiber that prevents aggregation of Alzheimer pathogenic proteins
20. Inhibition of Amyloid β Fibrillation by Nanoparticles Composed of Ovalbumin-derived Amphiphilic Peptides
21. Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation
22. Long-Term Ultra-High Hydrostatic Pressurized Brown Rice Intake Prevents Bone Mineral Density Decline in Elderly Japanese Individuals
23. Influence of Ultra-High Hydrostatic Pressurizing Brown Rice on Cognitive Functions and Mental Health of Elderly Japanese Individuals: A 2-Year Randomized and Controlled Trial
24. The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice
25. Amyloid precursor protein promotes endoplasmic reticulum stress-induced cell death via C/EBP homologous protein-mediated pathway
26. N-cadherin-based adhesion enhances Aβ release and decreases Aβ42/40 ratio
27. Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells
28. The New Generation of Acetylcholinesterase Inhibitors
29. Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity
30. Mechanisms of cell death of neural progenitor cells caused by trophic support deprivation
31. Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade
32. Serofendic acid, a neuroprotective substance derived from fetal calf serum, inhibits mitochondrial membrane depolarization and caspase-3 activation
33. Up-regulation of nicotinic acetylcholine receptors by central-type acetylcholinesterase inhibitors in rat cortical neurons
34. Serofendic acid prevents 6-hydroxydopamine-induced nigral neurodegeneration and drug-induced rotational asymmetry in hemi-parkinsonian rats
35. Serofendic acid prevents acute glutamate neurotoxicity in cultured cortical neurons
36. Design and synthesis of curcumin derivatives as tau and amyloid β dual aggregation inhibitors
37. Synthesis and biological evaluation of 1-(4-[ 18f]fluorobenzyl)-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine for in vivo studies of acetylcholinesterase
38. PE859, A Novel Curcumin Derivative, Inhibits Amyloid-β and Tau Aggregation, and Ameliorates Cognitive Dysfunction in Senescence-Accelerated Mouse Prone 8
39. Decrease of Amyloid-β Levels by Curcumin Derivative via Modulation of Amyloid-β Protein Precursor Trafficking
40. Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups
41. Integrin-Associated Protein Promotes Neuronal Differentiation of Neural Stem/Progenitor Cells
42. PE859, a Novel Tau Aggregation Inhibitor, Reduces Aggregated Tau and Prevents Onset and Progression of Neural Dysfunction In Vivo
43. Fundamental Study of Memory Impairment and Non-cognitive Behavioral Alterations in APPswe/PS1dE9 Mice
44. Design, synthesis, evaluation and QSAR analysis of N1-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors
45. Design, synthesis and evaluation of carbamate-modified (−)- N1-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors
46. Glycogen synthase kinase-3β activation mediates rotenone-induced cytotoxicity with the involvement of microtubule destabilization
47. Functional and molecular interactions between Rac1 and FE65
48. Invasion Precedes Tumor Mass Formation in a Malignant Brain Tumor Model of Genetically Modified Neural Stem Cells
49. ChemInform Abstract: Development of anti-Alzheimer′s Disease Drug Based on β-Amyloid Hypothesis
50. ChemInform Abstract: Discovery and Development of Donepezil Hydrochloride for the Treatment of Alzheimer′s Disease
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