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37 results on '"Sugito, Hiroki"'

2. Periodontal Regenerative Therapy Using rhFGF-2 and Deproteinized Bovine Bone Mineral versus rhFGF-2 Alone: 4-Year Extended Follow-Up of a Randomized Controlled Trial

Author

Seshima, Fumi, primary, Bizenjima, Takahiro, additional, Aoki, Hideto, additional, Imamura, Kentaro, additional, Kita, Daichi, additional, Irokawa, Daisuke, additional, Matsugami, Daisuke, additional, Kitamura, Yurie, additional, Yamashita, Keiko, additional, Sugito, Hiroki, additional, Tomita, Sachiyo, additional, and Saito, Atsushi, additional

Published
2022
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5. Periodontal surgery using rhFGF‐2 with deproteinized bovine bone mineral or rhFGF‐2 alone: 2‐year follow‐up of a randomized controlled trial

Author

Aoki, Hideto, primary, Bizenjima, Takahiro, additional, Seshima, Fumi, additional, Sato, Masahiro, additional, Irokawa, Daisuke, additional, Yoshikawa, Kouki, additional, Yoshida, Wataru, additional, Imamura, Kentaro, additional, Matsugami, Daisuke, additional, Kitamura, Yurie, additional, Kita, Daichi, additional, Sugito, Hiroki, additional, Tomita, Sachiyo, additional, and Saito, Atsushi, additional

Published
2020
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11. Periodontal surgery using rhFGF‐2 with deproteinized bovine bone mineral or rhFGF‐2 alone: 2‐year follow‐up of a randomized controlled trial.

Author

Aoki, Hideto, Bizenjima, Takahiro, Seshima, Fumi, Sato, Masahiro, Irokawa, Daisuke, Yoshikawa, Kouki, Yoshida, Wataru, Imamura, Kentaro, Matsugami, Daisuke, Kitamura, Yurie, Kita, Daichi, Sugito, Hiroki, Tomita, Sachiyo, and Saito, Atsushi

Subjects
PERIODONTITIS treatment, FIBROBLAST growth factor 2, MINERAL content of bones, BOVINE anatomy, BONE surgery, TRAUMATIC bone defects, AUTOGRAFTS, BONE regeneration, BONE substitutes, BONE grafting, COMPARATIVE studies, GROWTH factors, GUIDED tissue regeneration, PATIENT aftercare, ORAL surgery, HEALTH outcome assessment, PERIODONTITIS, POSTOPERATIVE period, TREATMENT effectiveness, DESCRIPTIVE statistics
Abstract

Aim: To compare outcomes of rhFGF‐2 + DBBM therapy with rhFGF‐2 alone in the treatment of intrabony defects. This study provides 2‐year follow‐up results from the previous randomized controlled trial. Materials and Methods: Defects were randomly allocated to receive rhFGF‐2 + DBBM (test) or rhFGF‐2 (control). Treated sites were re‐evaluated at 2 years postoperatively, using original clinical and patient‐centred measures. Results: Thirty‐eight sites were available for re‐evaluation. At 2 years, both groups showed a significant improvement in clinical attachment level (CAL) from baseline. A gain in CAL of 3.4 ± 1.3 mm in the test group and 3.1 ± 1.5 mm in the control group was found. No significant inter‐group difference was noted. Both groups showed a progressive increase in radiographic bone fill (RBF). The test treatment yielded greater RBF (56%) compared with the control group (41%). The control treatment performed better in contained defects in terms of CAL and RBF. There was no significant difference in patient‐reported outcomes between groups. Conclusions: At 2‐year follow‐up, the test and cotrol treatments were similarly effective in improving CAL, whereas the test treatment achieved a significantly greater RBF. In both treatments, favourable clinical, radiographic, and patient‐reported outcomes can be sustained for at least 2 years. Trial registration: The University Hospital Medical Information Network‐Clinical Trials Registry (UMIN‐CTR) 000025257. [ABSTRACT FROM AUTHOR]

Published
2021
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12. MOESM2 of Periodontal regenerative therapy with enamel matrix derivative in the treatment of intrabony defects: a prospective 2-year study

Author

Seshima, Fumi, Aoki, Hideto, Takeuchi, Takahiro, Suzuki, Eiichi, Irokawa, Daisuke, Makino-Oi, Asako, Sugito, Hiroki, Tomita, Sachiyo, and Saito, Atsushi

Abstract

Additional file 2: Figure S1. A representative treatment case. 53-year-old woman with severe chronic periodontitis. a. Preoperative clinical view. PD 7.0 mm, CAL 8.0 mm, INTRA 6.0 mm. b. During surgery; INTRA of the defect was 6.0 mm. c. Preoperative (baseline) radiograph, in the distal aspect of the mandibular right second molar. Angular bony defect is evident. d. Radiograph after 1 year. An improvement in radiolucency can be observed in the distal aspect. e. Radiograph after 2 year, showing further improvement in the distal aspect. PD 4.0Â mm, CAL 4.0 mm.

Published
2017
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14. Effect of Porous Xenographic Bone Graft with Collagen Barrier Membrane on Periodontal Regeneration.

Author

Yamada, Satoru, Shima, Nobushiro, Kitamura, Hidekazu, and Sugito, Hiroki

Subjects
BONE grafting, XENOGRAFTS, TRANSPLANTATION of organs, tissues, etc., REGENERATION (Biology), CEMENTUM, PERIODONTIUM, CONNECTIVE tissues, GUIDED tissue regeneration, PERIODONTAL disease
Abstract

The purpose of this study was to investigate the effect of porous xenographic bone graft (Bio-Oss) with a collagen barrier membrane (Bio-Gide) on formation of new cementum and new bone in experimental intrabony defects of dogs. The intrabony defects were treated by either guided tissue regeneration with the collagen membrane (control group) or the collagen membrane with the porous bone mineral graft (experimental group). After 8 weeks, the animals were sacrificed and the tissues were histologically examined. New cementum with inserting collagen fibers was observed on the exposed surfaces in both groups. The amount of new bone was significantly greater in the group using the bone graft with the membrane than in the control group. The use of the collagen barrier membrane in combination with the porous bone graft material may enhance new bone and cementum formation. [ABSTRACT FROM AUTHOR]

Published
2002

24. Recent Trends among Dental Residents at Tokyo Dental College

Author

Takahashi, Toshiyuki, primary, Furusawa, Masahiro, additional, Katakura, Akira, additional, Sugito, Hiroki, additional, Hirata, SoIchiro, additional, Ishii, Takuo, additional, Kameyama, Atsushi, additional, Noro, Akio, additional, Yamakura, Daiki, additional, Kondou, Yoshihiro, additional, Sugiyama, Toshiko, additional, Sugiyama, Setsuko, additional, Haruyama, Akiko, additional, and Asami, Masako, additional

Published
2013
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28. A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis

Author

Koyama, Eiki, primary, Shibukawa, Yoshihiro, additional, Nagayama, Motohiko, additional, Sugito, Hiroki, additional, Young, Blanche, additional, Yuasa, Takahito, additional, Okabe, Takahiro, additional, Ochiai, Takanaga, additional, Kamiya, Nobuhiko, additional, Rountree, Ryan B., additional, Kingsley, David M., additional, Iwamoto, Masahiro, additional, Enomoto-Iwamoto, Motomi, additional, and Pacifici, Maurizio, additional

Published
2008
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33. Clinical Evaluation for Collagen Membrane (BioMend) in Guided Tissue Regeneration.

Author

Nakaya, Hiroshi, primary, Ohsaki, Tadao, additional, Matsumura, Akiko, additional, Kiyonobu, Kohichi, additional, Konobu, Hiroyuki, additional, Kobayashi, Hiroshi, additional, Kamoi, Kyuichi, additional, Suzuki, Kuniharu, additional, Fujikawa, Kenji, additional, Yoshinuma, Naoto, additional, Nanba, Koichi, additional, Ito, Koichi, additional, Murai, Seidai, additional, Kitamura, Hidekazu, additional, Akiyama, Rieko, additional, Sekiguchi, Kazumi, additional, Sugito, Hiroki, additional, Yamada, Satoru, additional, Kawasaki, Fumitsugu, additional, Shirato, Shunsuke, additional, Sumimoto, Haruna, additional, Sakuraba, Eiichi, additional, Kobayashi, Kazuyuki, additional, Gomi, Kazuhiro, additional, Arai, Takashi, additional, Maida, Takeo, additional, and Tanaka, Osamu, additional

Published
1999
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35. Treatment of Stage III Grade C Periodontitis with Periodontal Regenerative Therapy including Guided Tissue Regeneration (GTR) and Recombinant Human Fibroblast Growth Factor (rhFGF)-2: A Case Report.

Author

Iwaki J, Imamura K, Tanaka K, Sugito H, and Saito A

Subjects
Female, Humans, Middle Aged, Follow-Up Studies, Periodontal Attachment Loss, Tokyo, Treatment Outcome, Alveolar Bone Loss etiology, Chronic Periodontitis complications, Chronic Periodontitis surgery, Fibroblast Growth Factors, Gingival Diseases surgery, Guided Tissue Regeneration, Periodontal
Abstract

This report describes a case of periodontitis treated with periodontal surgery including guided tissue regeneration (GTR) and recombinant human fibroblast growth factor (rhFGF)-2. The patient was a 54-year-old woman who visited the Tokyo Dental College Suidobashi Hospital with the chief complaint of swelling in the maxillary right gingiva. An initial examination revealed 30.4% of sites with a probing depth (PD) of ≥4 mm. The prevalence of sites with bleeding on probing was 57.7%. The plaque control record (PCR) score was 66.1%. Radiographic examination revealed vertical bone defects in the molar region. Based on these findings, the clinical diagnosis was generalized chronic periodontitis (Stage III, Grade C). Initial periodontal therapy yielded an improvement in periodontal conditions, with the PCR score reducing to 13.8%. Periodontal surgery was performed for teeth with a residual PD ≥4 mm. Guided tissue regeneration was performed on #37 and 47. A series of periodontal regenerative treatments comprising application of rhFGF-2 was performed on angular bone defects in #14, 15, 25, and 27. Open flap debridement was performed on #16, 17, 26, 36, and 46. Following evaluation, oral function was restored by placing all-ceramic crowns on #21 and 26. The patient was then placed on supportive periodontal therapy. In the present case of generalized chronic periodontitis, periodontal regenerative therapy with GTR and rhFGF-2 yielded stable periodontal conditions.

Published
2023
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36. Treatment Capabilities of Postgraduate Dental Trainees at Tokyo Dental College Suidobashi Hospital Based on Dental Services Income.

Author

Sugito H, Hirata S, Sakayori T, Sato Y, Furusawa M, and Yamashita S

Subjects
Employment, Hospitals, Humans, Japan, Salaries and Fringe Benefits, Tokyo, Ambulatory Care economics, Dental Care, Dentists economics, Income
Abstract

As of fiscal year 2006, it became compulsory for all newly licensed dentists in Japan to undergo a year of practical training at one of the designated training facilities found throughout the country as part of their postgraduate programs. The goal of this training is for the trainees to acquire diagnostic and therapeutic skills. While officially trainees, they are nonetheless regarded as members of staff. Clinical training emphasizes improving both technical skills and theoretical knowledge. However, taking on such trainees is sometimes considered unprofitable, as work productivity is claimed to be low. The purpose of this study was to compare work outcomes and income generated between trainees and part-time dentists working at the Tokyo Dental College Suidobashi Hospital. The part-time dentists comprised clinical instructors and dentists responsible for outpatients. Postgraduate dental trainees also generally conduct dental treatment for outpatients. Therefore, part-time dentists were considered the most suitable for a control group. No significant difference was observed in the total number of patients seen by either group by the final term of clinical training. Furthermore, no significant difference was observed in insurance-based dental treatment unit income (insured care unit income) per patient between the two groups from the mid-term period of training onwards. These results suggest that, although the trainees were less efficient in terms of time taken to provide a diagnosis and treatment, their performance was almost equal when viewed from the viewpoint of insured care provided. Taken together, this suggests that time-related care efficiency must be increased and specific training policies and strategies developed to improve the work productivity of dental trainees.

Published
2015
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37. Periodontal regeneration following transplantation of proliferating tissue derived from periodontal ligament into class III furcation defects in dogs.

Author

Murano Y, Ota M, Katayama A, Sugito H, Shibukawa Y, and Yamada S

Subjects
Animals, Bone and Bones pathology, Cell Proliferation, Dental Cementum pathology, Dogs, Fibroblast Growth Factor 2 metabolism, Furcation Defects diagnosis, Proliferating Cell Nuclear Antigen metabolism, RNA, Messenger metabolism, Regeneration, Time Factors, Tissue Transplantation methods, Vascular Endothelial Growth Factor A metabolism, Wound Healing, Furcation Defects etiology, Periodontal Ligament pathology, Tissue Transplantation adverse effects
Abstract

The aim of this study was to evaluate the healing of class III furcation defects following transplantation of proliferating tissue derived from periodontal ligament (pPDL). Two weeks after removing alveolar bone, pPDL was excised. Class III furcation defects were created in the mandibular premolars. pPDL was transplanted into the furcation defects in the experimental group, while no treatment was performed on the furcation defects in the controls. Two, four and eight weeks after surgery, histologic examination, quantitative RT-PCR, and immunohistochemistry were carried out. bFGF and VEGF mRNA showed a significant increase in pPDL. In the pPDL treatment group, new cementum regenerated around almost the entire circumference of the furcation, with new bone filling most of the defect, while the control group presented epithelial downgrowth and defects filled with connective tissue. These results provide histological evidence that pPDL plays an important role in wound healing by promoting periodontal regeneration in class III furcation defects.

Published
2006
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