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Your search keyword '"Suh, Bo Kyoung"' showing total 23 results
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23 results on '"Suh, Bo Kyoung"'

6. Gcap14 is a microtubule plus-end-tracking protein coordinating microtubule–actin crosstalk during neurodevelopment

Author

Mun, Dong Jin, primary, Goo, Bon Seong, additional, Suh, Bo Kyoung, additional, Hong, Ji-Ho, additional, Woo, Youngsik, additional, Kim, Soo Jeong, additional, Kim, Seunghyun, additional, Lee, Su Been, additional, Won, Yubin, additional, Yoo, Jin Yeong, additional, Cho, Eunbyul, additional, Jang, Eun Jin, additional, Nhung, Truong Thi My, additional, Triet, Hong Minh, additional, An, Hongyul, additional, Lee, Haeryun, additional, Nguyen, Minh Dang, additional, Park, Seung-Yeol, additional, Baek, Seung Tae, additional, and Park, Sang Ki, additional

Published
2023
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7. Schizophrenia-associated Mitotic Arrest Deficient-1 (MAD1) regulates the polarity of migrating neurons in the developing neocortex

Author

Goo, Bon Seong, primary, Mun, Dong Jin, additional, Kim, Seunghyun, additional, Nhung, Truong Thi My, additional, Lee, Su Been, additional, Woo, Youngsik, additional, Kim, Soo Jeong, additional, Suh, Bo Kyoung, additional, Park, Sung Jin, additional, Lee, Hee-Eun, additional, Park, Kunyou, additional, Jang, Hyunsoo, additional, Rah, Jong-Cheol, additional, Yoon, Ki-Jun, additional, Baek, Seung Tae, additional, Park, Seung-Yeol, additional, and Park, Sang Ki, additional

Published
2022
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8. Ratiometric measurement of MAM Ca2+ dynamics using a modified CalfluxVTN.

Author

Cho, Eunbyul, Woo, Youngsik, Suh, Yeongjun, Suh, Bo Kyoung, Kim, Soo Jeong, Nhung, Truong Thi My, Yoo, Jin Yeong, Nghi, Tran Diem, Lee, Su Been, Mun, Dong Jin, and Park, Sang Ki

Subjects
PARKINSON'S disease, LABORATORY mice, DOPAMINERGIC neurons
Abstract

Mitochondria-associated ER membrane (MAM) is a structure where these calcium-regulating organelles form close physical contact sites for efficient Ca2+ crosstalk. Despite the central importance of MAM Ca2+ dynamics in diverse biological processes, directly and specifically measuring Ca2+ concentrations inside MAM is technically challenging. Here, we develop MAM-Calflux, a MAM-specific BRET-based Ca2+ indicator. The successful application of the bimolecular fluorescence complementation (BiFC) concept highlights Ca2+-responsive BRET signals in MAM. The BiFC strategy imparts dual functionality as a Ca2+ indicator and quantitative structural marker specific for MAM. As a ratiometric Ca2+ indicator, MAM-Calflux estimates steady-state MAM Ca2+ levels. Finally, it enables the visualization of uneven intracellular distribution of MAM Ca2+ and the elucidation of abnormally accumulated MAM Ca2+ from the neurons of Parkinson's disease mouse model in both steady-state and stimulated conditions. Therefore, we propose that MAM-Calflux can be a versatile tool for ratiometrically measuring dynamic inter-organellar Ca2+ communication. MAM Ca2+ dynamics play an important role in diverse biological processes, but directly and specifically measuring Ca2+ concentrations in this region is technically challenging. Here the authors report a MAM-specific BRET-based Ca2+ indicator called MAM-Calflux, which works as both a Ca2+ indicator and a structural marker due to its ratiometric nature. [ABSTRACT FROM AUTHOR]

Published
2023
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12. Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis

Author

Woo, Youngsik, primary, Kim, Soo Jeong, additional, Suh, Bo Kyoung, additional, Kwak, Yongdo, additional, Jung, Hyun-Jin, additional, Nhung, Truong Thi My, additional, Mun, Dong Jin, additional, Hong, Ji-Ho, additional, Noh, Su-Jin, additional, Kim, Seunghyun, additional, Lee, Ahryoung, additional, Baek, Seung Tae, additional, Nguyen, Minh Dang, additional, Choe, Youngshik, additional, and Park, Sang Ki, additional

Published
2019
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13. Author response: Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis

Author

Woo, Youngsik, primary, Kim, Soo Jeong, additional, Suh, Bo Kyoung, additional, Kwak, Yongdo, additional, Jung, Hyun-Jin, additional, Nhung, Truong Thi My, additional, Mun, Dong Jin, additional, Hong, Ji-Ho, additional, Noh, Su-Jin, additional, Kim, Seunghyun, additional, Lee, Ahryoung, additional, Baek, Seung Tae, additional, Nguyen, Minh Dang, additional, Choe, Youngshik, additional, and Park, Sang Ki, additional

Published
2019
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15. KIN‐4/MAST kinase promotes PTEN‐mediated longevity of Caenorhabditis elegans via binding through a PDZ domain

Author

An, Seon Woo A., primary, Choi, Eun‐Seok, additional, Hwang, Wooseon, additional, Son, Heehwa G., additional, Yang, Jae‐Seong, additional, Seo, Keunhee, additional, Nam, Hyun‐Jun, additional, Nguyen, Nhung T. H., additional, Kim, Eun Ji E., additional, Suh, Bo Kyoung, additional, Kim, Youngran, additional, Nakano, Shunji, additional, Ryu, Youngjae, additional, Man Ha, Chang, additional, Mori, Ikue, additional, Park, Sang Ki, additional, Yoo, Joo‐Yeon, additional, Kim, Sanguk, additional, and Lee, Seung‐Jae V., additional

Published
2019
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16. Regulation of the actin cytoskeleton by the Ndel1-Tara complex is critical for cell migration

Author

Hong, Ji-Ho, primary, Kwak, Yongdo, additional, Woo, Youngsik, additional, Park, Cana, additional, Lee, Seol-Ae, additional, Lee, Haeryun, additional, Park, Sung Jin, additional, Suh, Yeongjun, additional, Suh, Bo Kyoung, additional, Goo, Bon Seong, additional, Mun, Dong Jin, additional, Sanada, Kamon, additional, Nguyen, Minh Dang, additional, and Park, Sang Ki, additional

Published
2016
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23. Ratiometric measurement of MAM Ca 2+ dynamics using a modified CalfluxVTN.

Author

Cho E, Woo Y, Suh Y, Suh BK, Kim SJ, Nhung TTM, Yoo JY, Nghi TD, Lee SB, Mun DJ, and Park SK

Subjects
Mice, Animals, Mitochondria, Endoplasmic Reticulum metabolism
Abstract

Mitochondria-associated ER membrane (MAM) is a structure where these calcium-regulating organelles form close physical contact sites for efficient Ca 2+ crosstalk. Despite the central importance of MAM Ca 2+ dynamics in diverse biological processes, directly and specifically measuring Ca 2+ concentrations inside MAM is technically challenging. Here, we develop MAM-Calflux, a MAM-specific BRET-based Ca 2+ indicator. The successful application of the bimolecular fluorescence complementation (BiFC) concept highlights Ca 2+ -responsive BRET signals in MAM. The BiFC strategy imparts dual functionality as a Ca 2+ indicator and quantitative structural marker specific for MAM. As a ratiometric Ca 2+ indicator, MAM-Calflux estimates steady-state MAM Ca 2+ levels. Finally, it enables the visualization of uneven intracellular distribution of MAM Ca 2+ and the elucidation of abnormally accumulated MAM Ca 2+ from the neurons of Parkinson's disease mouse model in both steady-state and stimulated conditions. Therefore, we propose that MAM-Calflux can be a versatile tool for ratiometrically measuring dynamic inter-organellar Ca 2+ communication., (© 2023. The Author(s).)

Published
2023
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