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1,096 results on '"Sui, Hong"'

3. Single-Slice Hounsfield Unit (HU) Value of the Chinese Proximal Humerus on Routine Chest CT: A Study on Opportunistically Screening for Low Bone Density/Valor de Unidad Hounsfield (HU) de Corte Unico del Humero Proximal Chino en una Tomografia Computarizada de Torax de Rutina: Un Estudio sobre la Deteccion Oportunista de Baja Densidad Osea

Author

Zhao, Chen-Xu, Liu, Cong, Liu, Xin-Ting, Chi, Yan-Yan, Yu, Sheng-Bo, Zheng, Nan, Zhang, Jian-Fei, Xu, Ying-Yang, Sui, Hong Jin, and Xu, Qiang

Published
2024

26. Identification of the major photodegradant in metronidazole by LC-PDA-MS and its reveal in compendial methods

Author

Mei-Ling Chen, Hong-Xia Xu, Wei-Feng Yuan, Sui-Hong Zhao, Xue Li, Lan-Xin Zhu, Zong-Yong Shen, Yu-Jing Liu, Ming-Juan Wang, Ang Ma, Jos Hoogmartens, and Erwin Adams

Subjects
Medicine, Science
Abstract

Abstract Metronidazole in aqueous solution is sensitive to light and UV irradiation, leading to the formation of N-(2-hydroxyethyl)-5-methyl-l,2,4-oxadiazole-3-carboxamide. This is revealed here by liquid chromatography with tandem photo diode array detection and mass spectrometry (LC-PDA-MS) and further verified by comparison with the corresponding reference substance and proton nuclear magnetic resonance (1H-NMR). However, in current compendial tests for related substances/organic impurities of metronidazole, the above photolytic degradant could not be detected. Thus, when photodegradation of metronidazole occurs, it could not be demonstrated. In our study, an improved LC method was developed and validated, which includes a detection at a wavelength of 230 nm and optimization of mobile phase composition thereby a better separation was obtained.

Published
2022
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27. Regional distribution of microvasculature within the canine femoral head: a study of plastinated tissue histology and 3D reconstruction.

Author

Shah, M. Adeel Alam, Tang, Wei, Ma, Yue, Zhe, Wang, Yu, Sheng-Bo, and Sui, Hong-Jin

Abstract

Background: Understanding the intraosseous vascularity of the femoral head is important for preserving its structural integrity and function. Disruptions in microcirculation can lead to osteonecrosis of the femoral head (ONFH). This anatomical study aimed to quantify the regional distribution of the microvessels within the trabecular bone of the femoral head. Methods: Eleven beagles (five males, six females) were infused with intra-aortic radiopaque silicon, followed by micro-computed tomography imaging and 3D modelling using Avizo. EXAKT non-decalcified plastinated tissue histology of the proximal femur was performed and quantified using the Bioquant Osteo semi-automated histomorphometry with ImageJ. Vascular diameter, density, length density, and osteochondral parameters were calculated and compared within the subcortical and central zones of the femoral head in both sexes. Results: A well-developed intraosseous microvascular network was identified within the trabecular struts, resembling Volkmann's canals and integrating into Haversian system at the subchondral compact bone. Dense capillary networks traversed both trabecular and cortical bone to supply articular cartilage. Subcortical microvasculature was denser, with thinner diameters and shorter lengths compared to the central zone. The middle part of the femoral head displayed higher subcortical vascular density compared to superior and inferior parts. Strong positive correlations were observed between the endocortical area, tissue area, mean cortical width, bone surface and trabecular spacing. A moderate negative correlation was found between quiescent surface and cartilage density. No significant sex differences were observed in vascularity or bone metrics. Conclusion: Based on the spatial distribution of the microvasculature, the central zone serves as a conduit for primary intraosseous blood vessels, supplying the subcortical zone, including the cortex and articular cartilage. These findings establish baseline reference values for normal intraosseous microvessels and bone metrics in canine anatomy, which can be utilized for diagnosing and treating osteochondral diseases. [ABSTRACT FROM AUTHOR]

Published
2025
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28. A new analogous organ in bony fishes and amphibians: an anatomical structure related with the cerebrospinal fluid circulation.

Author

Chen, Cheng, Yang, Heng, Song, Yang, Dong, Yun-Li, Zhang, Jing, Shah, Muhammad Adeel Alam, Qin, Tao, Zheng, Nan, Yu, Sheng-Bo, Xiong, Yu-Yu, Zhang, Jian-Fei, and Sui, Hong-Jin

Subjects
OSTEICHTHYES, DURA mater, SPINAL canal, XENOPUS laevis, CEREBROSPINAL fluid
Abstract

The myodural bridge (MDB) was described as a dense fibrous tissue connecting the suboccipital musculature with the spinal dura mater. Now, the concept of the MDB was perceived as an exact anatomical structure likely essential for cerebrospinal fluid (CSF) circulation. The MDB has been shown to be universal across mammals, reptiles, and birds. To determine the existence of the MDB in other vertebrates on morphological study, representatives in amphibians and bony fishes were examined. It was found that the dense fibrous tissue connected the interarcuales muscle (IAR) and the spinal dura mater in the Xenopus laevis. In four examined fish species, somatic muscle fibers were directly anchored to the vertebral canal membrane. This observation led to the hypothesis that, during movement, these muscles may exert a pulling force on the membrane, generating negative pressure. It is speculated that this may serve as the driving force for CSF circulation. Thus, this connection suggests a functional similarity to the MDB observed in other vertebrate species. Based on this finding, the study proposes the MDB as a functionally analogous structure with a universal existence in amphibians and bony fishes. [ABSTRACT FROM AUTHOR]

Published
2025
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