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In order to study the optimization of the prefabricated concrete frame building based on the dynamic equation of the eccentric structure's horizontal-torsional coupling. First, the author analyzes the characteristics of several current representative structural forms and the problems existing in the process of industrialization. Through research on prefabricated houses at home and abroad, the key technologies involved in key processes such as design, component production, and prefabricated component installation are discussed in detail, and the problems existing in the existing technology are analyzed. Then, for a single-layer eccentric structure with soil-structure interaction, the dynamic equation is established to solve the parameters that affect the dynamic characteristics of the eccentric structural system. Finally, combined with the actual engineering, the application status of the key technologies in the construction process is analyzed, and the relevant research results are used in the project to verify the validity of the research results. The experimental results show that: Through engineering practice, we have a clearer understanding of the design and construction of prefabricated buildings, and have a deeper understanding of related technologies, and also verified the feasibility of related technologies in engineering.

Food proteins and peptides are generally considered a source of dietary antioxidants. The aim of this study was to investigate the antioxidant activity, allergenicity, and peptide profiles of whey protein hydrolysates (WPHs) using different hydrolysis methods. The results demonstrated that the degrees of hydrolysis of the hydrolysates with one-step (O-AD) and two-step (T-AD) methods reached 16.25% and 17.64%, respectively. The size exclusion chromatography results showed that the O-AD had a higher content of >5 and <0.3 kDa, and the distribution of peptide profiles for the two hydrolysates was significantly different. Furthermore, 5 bioactive peptides and 15 allergenic peptides were identified using peptidomics. The peptide profiles and the composition of the master proteins of the O-AD and T-AD were different. The DPPH and ABTS radical scavenging abilities of WPHs were measured, and hydrolysates were found to exhibit a strong radical scavenging ability after being treated using different hydrolysis methods. An enzyme-linked immunosorbent assay showed that the sensitization of WPHs was significantly reduced. This study may provide useful information regarding the antioxidant properties and allergenicity of WPHs. [ABSTRACT FROM AUTHOR]

Surface‐enhanced Raman scattering (SERS) imaging technology faces significant technical bottlenecks in ensuring balanced spatial resolution, preventing image bias induced by substrate heterogeneity, accurate quantitative analysis, and substrate preparation that enhances Raman signal strength on a global scale. To systematically solve these problems, artificial intelligence techniques are applied to analyze the signals of pesticides based on 3D and dynamic SERS imaging. Utilizing perovskite/silver nanoparticles composites (CaTiO3/Ag@BONPs) as enhanced substrates, enabling it not only to cleanse pesticide residues from the surface to pulp of fruits and vegetables, but also to investigate the penetration dynamics of an array of pesticides (chlorpyrifos, thiabendazole, thiram, and acetamiprid). The findings challenge existing paradigms, unveiling a previously unnoticed weakening process during pesticide invasion and revealing the surprising permeability of non‐systemic pesticides. Of particular note is easy to overlook that the combined application of pesticides can inadvertently intensify their invasive capacity due to pesticide interactions. The innovative study delves into the realm of pesticide penetration, propelling a paradigm shift in the understanding of food safety. Meanwhile, this strategy provides strong support for the cutting‐edge application of SERS imaging technology and also brings valuable reference and enlightenment for researchers in related fields. [ABSTRACT FROM AUTHOR]

To synthesize an effective and versatile nano-platform serving as a promising carrier for controlled drug delivery, visible-light-induced diselenide-crosslinked polyurethane micelles were designed and prepared for ROS-triggered on-demand doxorubicin (DOX) release. A rationally designed amphiphilic block copolymer, poly(ethylene glycol)-b-poly(diselenolane diol-co-isophorone diisocyanate)-b-poly(ethylene glycol) (PEG-b-PUSe-b-PEG), which incorporates dangling diselenolane groups within the hydrophobic PU segments, was initially synthesized through the polycondensation reaction. In aqueous media, this type of amphiphilic block copolymer can self-assemble into micellar aggregates and encapsulate DOX within the micellar core, forming DOX-loaded micelles that are subsequently in situ core-crosslinked by diselenides via a visible-light-triggered metathesis reaction of Se-Se bonds. Compared with the non-crosslinked micelles (NCLMs), the as-prepared diselenide-crosslinked micelles (CLMs) exhibited a smaller particle size and improved colloidal stability. In vitro release studies have demonstrated suppressed drug release behavior for CLMs in physiological conditions, as compared to the NCLMs, whereas a burst release of DOX occurred upon exposure to an oxidation environment. Moreover, MTT assay results have revealed that the crosslinked polyurethane micelles displayed no significant cytotoxicity towards HeLa cells. Cellular uptake analyses have suggested the effective internalization of DOX-loaded crosslinked micelles and DOX release within cancer cells. These findings suggest that this kind of ROS-triggered reversibly crosslinked polyurethane micelles hold significant potential as a ROS-responsive drug delivery system. [ABSTRACT FROM AUTHOR]

The effect of different thermal treatments including pasteurisation, ultra‐pasteurisation, ultra‐high temperature instantaneous sterilisation and in‐container sterilisation on physicochemical properties and peptide profiles of infant formula protein model after in vitro digestion were investigated. Results indicated that different extent of protein–protein and protein–lactose interactions caused different particle size, colour, functional groups and thermal properties. Peptide profiles were also different after in vitro digestion. About 32, 4, 15, 157 and 42 unique peptides, as well as 14, 10, 12, 13 and 10 bioactive peptides were identified in the five groups, respectively. Pasteurisation may be better for the processing of infant formula. [ABSTRACT FROM AUTHOR]

In order to realize the utilization of solid waste resource.A novel adsorbent, buckwheat shell-based activated carbon has been developed by chemical activation when applying waste buckwheat hull as thraw material.The authors optimized the activation temperature, activation time, type of activator, mass ratio of buckwheat hull and activator in the preparation process through single factor method.The adsorption efficiency of the optimized buckwheat-shell activated carbon was investigated by iodine value and methylene blue value.Pore structure, microcrystalline structure and micro-surface morphology of activated carbon were characterized by gas adsorption instrument, X-ray diffraction and scanning electron microscopy.The results showed that the optimized buckwheat shell-based activated carbon exhibited the highest adsorption capacity when applying phosphoric acid as the activator, the activation time of 90 min, activation temperature of 500℃, mass ratio of buckwheat shell and activator is 1:3.The iodine value and methylene blue value of the optimized buckwheat shell-based activated carbon were 765.8 mg/g and 222.2 mg/g respectively, and the methylene blue value of the optimized buckwheat shell-based activated carbon was higher than that of the three commercial activated carbons.Moreover, the optimized buckwheat shell-based activated carbon hosted the highest mesopore percentage (96.8%) and higher total pore volume (0.666 cm3/g) than that of the coal-based and coconut shell activated carbons, and the BET surface area (785.3 m2/g) was similar to the commercial activated carbons, indicating that a novel buckwheat shell-based activated carbon with strong mesopore, high adsorption capacity has been developed when applying waste buckwheat hull as raw material and phosphate as the activator.