Author: "Sun, Y.V." - Searchworks@Jio Institute Digital Library Search Results

13 results on '"Sun, Y.V."'

1. The power of genetic diversity in genome-wide association studies of lipids

Author: Graham, S.E., Clarke, S.L., Wu, K.H., Kanoni, S., Zajac, G.J.M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T.W., Locke, A.E., Marouli, E., Hwang, M.Y., Han, S., Narita, A., Choudhury, A., Bentley, A.R., Ekoru, K., Verma, A., Trivedi, B., Martin, H.C., Hunt, K.A., Hui, Q., Klarin, D., Zhu, X, Thorleifsson, G., Helgadottir, A., Gudbjartsson, D.F., Holm, H., Olafsson, I., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B.M., Rasheed, H., Ruotsalainen, S.E., Havulinna, A.S., Veturi, Y., Feng, Q., Rosenthal, E.A., Lingren, T., Pacheco, J.A., Pendergrass, S.A., Haessler, J., Giulianini, F., Bradford, Y., Miller, J.E., Campbell, A., Lin, K., Millwood, I.Y., Hindy, G., Rasheed, A., Faul, J.D., Zhao, W., Weir, D.R., Turman, C., Huang, H., Graff, M, Mahajan, A., Brown, M.R., Zhang, W., Yu, K., Schmidt, E.M., Pandit, A., Gustafsson, S., Yin, X., Luan, J., Zhao, J.H., Matsuda, F., Jang, H.M., Yoon, K., Medina-Gomez, C., Pitsillides, A., Hottenga, J.J., Willemsen, G., Wood, A.R., Ji, Y., Gao, Z, Haworth, S., Mitchell, R.E., Chai, J.F., Aadahl, M., Yao, J., Manichaikul, A., Warren, H.R., Ramirez, J., Bork-Jensen, J., Kårhus, L.L., Goel, A., Sabater-Lleal, M., Noordam, R., Sidore, C., Fiorillo, E., McDaid, A.F., Marques-Vidal, P., Wielscher, M., Trompet, S., Sattar, N., Galesloot, T.E., Kiemeney, B., Graaf, J. de, Lores de Motta, L., Pauper, M., Hollander, A.I. den, Sun, Y.V., Willer, C.J., Graham, S.E., Clarke, S.L., Wu, K.H., Kanoni, S., Zajac, G.J.M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T.W., Locke, A.E., Marouli, E., Hwang, M.Y., Han, S., Narita, A., Choudhury, A., Bentley, A.R., Ekoru, K., Verma, A., Trivedi, B., Martin, H.C., Hunt, K.A., Hui, Q., Klarin, D., Zhu, X, Thorleifsson, G., Helgadottir, A., Gudbjartsson, D.F., Holm, H., Olafsson, I., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B.M., Rasheed, H., Ruotsalainen, S.E., Havulinna, A.S., Veturi, Y., Feng, Q., Rosenthal, E.A., Lingren, T., Pacheco, J.A., Pendergrass, S.A., Haessler, J., Giulianini, F., Bradford, Y., Miller, J.E., Campbell, A., Lin, K., Millwood, I.Y., Hindy, G., Rasheed, A., Faul, J.D., Zhao, W., Weir, D.R., Turman, C., Huang, H., Graff, M, Mahajan, A., Brown, M.R., Zhang, W., Yu, K., Schmidt, E.M., Pandit, A., Gustafsson, S., Yin, X., Luan, J., Zhao, J.H., Matsuda, F., Jang, H.M., Yoon, K., Medina-Gomez, C., Pitsillides, A., Hottenga, J.J., Willemsen, G., Wood, A.R., Ji, Y., Gao, Z, Haworth, S., Mitchell, R.E., Chai, J.F., Aadahl, M., Yao, J., Manichaikul, A., Warren, H.R., Ramirez, J., Bork-Jensen, J., Kårhus, L.L., Goel, A., Sabater-Lleal, M., Noordam, R., Sidore, C., Fiorillo, E., McDaid, A.F., Marques-Vidal, P., Wielscher, M., Trompet, S., Sattar, N., Galesloot, T.E., Kiemeney, B., Graaf, J. de, Lores de Motta, L., Pauper, M., Hollander, A.I. den, Sun, Y.V., and Willer, C.J.
Abstract: Item does not contain fulltext, Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns and medication use(1). Despite advances in prevention and treatment, in particular through reducing low-density lipoprotein cholesterol levels(2), heart disease remains the leading cause of death worldwide(3). Genome-wideassociation studies (GWAS) of blood lipid levels have led to important biological and clinical insights, as well as new drug targets, for cardiovascular disease. However, most previous GWAS(4-23) have been conducted in European ancestry populations and may have missed genetic variants that contribute to lipid-level variation in other ancestry groups. These include differences in allele frequencies, effect sizes and linkage-disequilibrium patterns(24). Here we conduct a multi-ancestry, genome-wide genetic discovery meta-analysis of lipid levels in approximately 1.65 million individuals, including 350,000 of non-European ancestries. We quantify the gain in studying non-European ancestries and provide evidence to support the expansion of recruitment of additional ancestries, even with relatively small sample sizes. We find that increasing diversity rather than studying additional individuals of European ancestry results in substantial improvements in fine-mapping functional variants and portability of polygenic prediction (evaluated in approximately 295,000 individuals from 7 ancestry groupings). Modest gains in the number of discovered loci and ancestry-specific variants were also achieved. As GWAS expand emphasis beyond the identification of genes and fundamental biology towards the use of genetic variants for preventive and precision medicine(25), we anticipate that increased diversity of participants will lead to more accurate and equitable(26) application of polygenic scores in clinical practice.
Published: 2021

2. Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism

Author: Lindstrom, S., Wang, L., Smith, E.N., Gordon, W., Vlieg, A.V., Andrade, M. de, Brody, J.A., Pattee, J.W., Haessler, J., Brumpton, B., Chasman, D.I., Suchon, P., Chen, M.H., Turman, C., Germain, M., Wiggins, K.L., MacDonald, J., Braekkan, S.K., Armasu, S.M., Pankratz, N., Jackson, R.D., Nielsen, J.B., Giulianini, F., Puurunen, M.K., Ibrahim, M., Heckbert, S.R., Damrauer, S.M., Natarajan, P., Klarin, D., Vries, P.S. de, Sabater-Lleal, M., Huffman, J.E., Bammler, T.K., Frazer, K.A., McCauley, B.M., Taylor, K., Pankow, J.S., Reiner, A.P., Gabrielsen, M.E., Deleuze, J.F., O'Donnell, C.J., Kim, J., McKnight, B., Kraft, P., Hansen, J.B., Rosendaal, F.R., Heit, J.A., Psaty, B.M., Tang, W.H., Kooperberg, C., Hveem, K., Ridker, P.M., Morange, P.E., Johnson, A.D., Kabrhel, C., Tregouet, D.A., Smith, N.L., Busenkell, E., Judy, R., Lynch, J., Levin, M., Aragam, J.H.K., Chaffin, M., Haas, M., Assimes, T.L., Huang, J., Lee, K.M., Shao, Q., Huang, Y.F., Sun, Y.V., Vujkovic, M., Saleheen, D., Miller, D.R., Reaven, P., DuVall, S., Boden, W., Pyarajan, S., Henke, P., Gaziano, J.M., Concato, J., Rader, D.J., Cho, K., Chang, K.M., Wilson, P.W.F., Tsao, P.S., Kathiresan, S., Obi, A., Million Veteran Program, CHARGE Hemostasis Working Grp, INVENT Consortium, Program in Genetic Epidemiology and Statistical Genetics (PGESG - BOSTON), Harvard School of Public Health, University of Washington [Seattle], The Scripps Translational Science Institute and Scripps Health, Department of Thrombosis and Haemostasis, Leiden University Medical Center (LUMC), Department of Health Sciences Research [Mayo Clinic] (HSR), Mayo Clinic, University of Minnesota System, Fred Hutchinson Cancer Research Center [Seattle] (FHCRC), Brigham and Women's Hospital [Boston], Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Laboratoire d'hématologie biologique [Hôpital de la Timone - Hôpital Nord - APHM], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), National Institutes of Health [Bethesda] (NIH), Harvard T.H. Chan School of Public Health, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Biorobotics Lab (University of Washington), University of South-Eastern Norway (USN), Department of Health Sciences Research, Ohio State University [Columbus] (OSU), Nutrition, obésité et risque thrombotique (NORT), Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Los Angeles Biomedical Research Institute (LA BioMed), University of Augsburg [Augsburg], Centre National de Génotypage (CNG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Department of Epidemiology, Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, University of Minnesota [Twin Cities] (UMN), Norwegian University of Science and Technology [Trondheim] (NTNU), Norwegian University of Science and Technology (NTNU), Department of Emergency Medicine, Massachusetts General Hospital [Boston], Universiteit Leiden-Universiteit Leiden, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Augsburg (UNIA), and Universiteit Leiden
Subjects: 0301 basic medicine, Genetics, [SDV]Life Sciences [q-bio], Immunology, Genome-wide association study, Cell Biology, Hematology, 030204 cardiovascular system & hematology, Biology, equipment and supplies, Biochemistry, 3. Good health, Transcriptome, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Mendelian randomization, Expression quantitative trait loci, Gene expression, cardiovascular diseases, Gene, Genetic association, Whole blood
Abstract: Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To advance our understanding of the biology contributing to VTE, we conducted a genome-wide association study (GWAS) of VTE and a transcriptome-wide association study (TWAS) based on imputed gene expression from whole blood and liver. We meta-analyzed GWAS data from 18 studies for 30 234 VTE cases and 172 122 controls and assessed the association between 12 923 718 genetic variants and VTE. We generated variant prediction scores of gene expression from whole blood and liver tissue and assessed them for association with VTE. Mendelian randomization analyses were conducted for traits genetically associated with novel VTE loci. We identified 34 independent genetic signals for VTE risk from GWAS meta-analysis, of which 14 are newly reported associations. This included 11 newly associated genetic loci (C1orf198, PLEK, OSMR-AS1, NUGGC/SCARA5, GRK5, MPHOSPH9, ARID4A, PLCG2, SMG6, EIF5A, and STX10) of which 6 replicated, and 3 new independent signals in 3 known genes. Further, TWAS identified 5 additional genetic loci with imputed gene expression levels differing between cases and controls in whole blood (SH2B3, SPSB1, RP11-747H7.3, RP4-737E23.2) and in liver (ERAP1). At some GWAS loci, we found suggestive evidence that the VTE association signal for novel and previously known regions colocalized with expression quantitative trait locus signals. Mendelian randomization analyses suggested that blood traits may contribute to the underlying risk of VTE. To conclude, we identified 16 novel susceptibility loci for VTE; for some loci, the association signals are likely mediated through gene expression of nearby genes.
Published: 2019
Full Text: View/download PDF

3. Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events A GENIUS-CHD Study of Individual Participant Data

Author: Patel, R.S., Schmidt, A.F., Tragante, V., McCubrey, R.O., Holmes, M.V., Howe, L.J., Direk, K., Akerblom, A., Leander, K., Virani, S.S., Kaminski, K.A., Muehlschlegel, J.D., Dube, M.P., Allayee, H., Almgren, P., Alver, M., Baranova, E.V., Behlouli, H., Boeckx, B., Braund, P.S., Breitling, L.P., Delgado, G., Duarte, N.E., Dufresne, L., Eriksson, N., Foco, L., Gijsberts, C.M., Gong, Y., Hartiala, J., Heydarpour, M., Hubacek, J.A., Kleber, M., Kofink, D., Kuukasjarvi, P., Lee, V.V., Leiherer, A., Lenzini, P.A., Levin, D., Lyytikainen, L.P., Martinelli, N., Mons, U., Nelson, C.P., Nikus, K., Pilbrow, A.P., Ploski, R., Sun, Y.V., Tanck, M.W.T., Tang, W.H.W., Trompet, S., Laan, S.W. van der, Setten, J. van, Vilmundarson, R.O., Anselmi, C.V., Vlachopoulou, E., Boerwinkle, E., Briguori, C., Carlquist, J.F., Carruthers, K.F., Casu, G., Deanfield, J., Deloukas, P., Dudbridge, F., Fitzpatrick, N., Gigante, B., James, S., Lokki, M.L., Lotufo, P.A., Marziliano, N., Mordi, I.R., Muhlestein, J.B., Cheh, C.N., Pitha, J., Saely, C.H., Samman-Tahhan, A., Sandesara, P.B., Teren, A., Timmis, A., Werf, F. van de, Wauters, E., Wilde, A.A.M., Ford, I., Stott, D.J., Algra, A., Andreassi, M.G., Ardissino, D., Arsenault, B.J., Ballantyne, C.M., Bergmeijer, T.O., Bezzina, C.R., Body, S.C., Bogaty, P., Borst, G.J. de, Brenner, H., Burkhardt, R., Carpeggiani, C., Condorelli, G., Cooper-DeHoff, R.M., Cresci, S., Faire, U. de, Doughty, R.N., Drexel, H., Engert, J.C., Fox, K.A.A., Girelli, D., Hagstrom, E., Hazen, S.L., Held, C., Hemingway, H., Hoefer, I.E., Hovingh, G.K., Johnson, J.A., Jong, P.A. de, Jukema, J.W., Kaczor, M.P., Kahonen, M., Kettner, J., Kiliszek, M., Klungel, O.H., Lagerqvist, B., Lambrechts, D., Laurikka, J.O., Lehtimaki, T., Lindholm, D., Mahmoodi, B.K., Maitland-van der Zee, A.H., McPherson, R., Melander, O., Metspalu, A., Pepinski, W., Olivieri, O., Opolski, G., Palmer, C.N., Pasterkamp, G., Pepine, C.J., Pereira, A.C., Note, L., Quyyumi, A.A., Richards, A.M., Sanak, M., Scholz, M., Siegbahn, A., Sinisalo, J., Smith, J.G., Spertus, J.A., Stewart, A.F.R., Szczeklik, W., Szpakowicz, A., Berg, J.M. ten, Thanassoulis, G., Thieiy, J., Graaf, Y. van der, Visseren, F.L.J., Waltenberger, J., Harst, P. van der, Tardif, J.C., Sattar, N., Lang, C.C., Pare, G., Brophy, J.M., Anderson, J.L., Marz, W., Wallentin, L., Cameron, V.A., Horne, B.D., Samani, N.J., Hingorani, A.D., Asselbergs, F.W., and CARDIo-GRAMPlusC4D Consortium
Subjects: myocardial infarction, risk factor, cardiovascular diseases, chromosome, genetic, variation, secondary prevention
Abstract: BACKGROUND: Genetic variation at chromosome 9p21 is a recognized risk factor for coronary heart disease (CHD). However, its effect on disease progression and subsequent events is unclear, raising questions about its value for stratification of residual risk.METHODS: A variant at chromosome 9p21 (rs1333049) was tested for association with subsequent events during follow-up in 103 357 Europeans with established CHD at baseline from the GENIUS-CHD (Genetics of Subsequent Coronary Heart Disease) Consortium (73.1% male, mean age 62.9 years). The primary outcome, subsequent CHD death or myocardial infarction (CHD death/myocardial infarction), occurred in 13 040 of the 93 115 participants with available outcome data. Effect estimates were compared with case/control risk obtained from the CARDIoGRAMplusC4D consortium (Coronary Artery Disease Genome-wide Replication and Meta-analysis [CARDIoGRAM] plus The Coronary Artery Disease [C4D] Genetics) including 47 222 CHD cases and 122 264 controls free of CHD.RESULTS: Meta-analyses revealed no significant association between chromosome 9p21 and the primary outcome of CHD death/myocardial infarction among those with established CHD at baseline (GENIUSCHD odds ratio, 1.02; 95% CI, 0.99-1.05). This contrasted with a strong association in CARDIoGRAMPlusC4D odds ratio 1.20; 95% CI, 1.18-1.22; P for interaction < 0.001 compared with the GENIUS-CHD estimate. Similarly, no clear associations were identified for additional subsequent outcomes, including all-cause death, although we found a modest positive association between chromosome 9p21 and subsequent revascularization (odds ratio, 1.07; 95% CI, 1.04-1.09).CONCLUSIONS: In contrast to studies comparing individuals with CHD to disease-free controls, we found no clear association between genetic variation at chromosome 9p21 and risk of subsequent acute CHD events when all individuals had CHD at baseline. However, the association with subsequent revascularization may support the postulated mechanism of chromosome 9p21 for promoting atheroma development.
Published: 2019

4. Subsequent Event Risk in Individuals With Established Coronary Heart Disease

Author: Patel, R.S. (Riyaz), Tragante, V. (Vinicius), Schmidt, A.F. (Amand), McCubrey, R.O. (Raymond O.), Holmes, M.V. (Michael), Howe, L.J. (Laurence J.), Direk, K. (Kenan), Åkerblom, A. (Axel), Leander, K. (Karin), Virani, S.S. (Salim), Kaminski, K.A. (Karol A.), Muehlschlegel, J.D. (Jochen), Allayee, H. (Hooman), Almgren, P. (Peter), Alver, M. (Maris), Baranova, E.V. (Ekaterina V.), Behloui, H. (Hassan), Boeckx, B. (Bram), Braund, P.S. (Peter), Breitling, L.P. (Lutz), Delgado, G., Duarte, N.E. (Nubia E.), Dubé, G.P. (Gregory), Dufresne, L. (Line), Eriksson, N. (Niclas), Foco, L. (Luisa), Scholz, M. (Markus), Gijsberts, C.M. (Crystel M.), Glinge, C. (Charlotte), Gong, Y. (Yan), Hartiala, J. (Jaana), Heydarpour, M. (Mahyar), Hubacek, J.A. (Jaroslav A.), Kleber, M.E. (Marcus), Kofink, D. (Daniel), Kotti, S. (Salma), Kuukasjärvi, P. (Pekka), Lee, V.-V. (Vei-Vei), Leiherer, A. (Andreas), Lenzini, P.A. (Petra A.), Levin, D. (Daniel), Lyytikäinen, L.-P. (Leo-Pekka), Martinelli, N. (Nicola), Mons, U. (Ute), Nelson, C.P. (Christopher P.), Nikus, K. (Kjell), Pilbrow, A.P. (Anna P.), Ploski, R. (Rafal), Sun, Y.V. (Yan V.), Tanck, M.W.T. (Michael), Tang, W. (W.), Trompet, S. (Stella), van der Laan, S.W. (Sander W.), Setten, J. (Jessica) van, Vilmundarson, R.O. (Ragnar O.), Viviani Anselmi, C. (Chiara), Vlachopoulou, E. (Efthymia), Al Ali, L. (Lawien), Boerwinkle, E.A. (Eric), Briguori, C. (Carlo), Carlquist, J.F. (John), Carruthers, K.F. (Kathryn), Casu, G. (Gavino), Deanfield, J. (John), Deloukas, P. (Panos), Dudbridge, F. (Frank), Engstrøm, T. (Thomas), Fitzpatrick, N. (Natalie), Fox, K.M. (Kim), Gigante, B. (Bruna), James, S.K. (Stefan), Lokki, M.-L. (Marja-Liisa), Lotufo, P.A. (Paulo A.), Marziliano, N. (Nicola), Mordi, I.R. (Ify R.), Muhlestein, J.B. (Joseph), Newton-Cheh, C. (Christopher), Pitha, J. (Jan), Saely, C.H. (Christoph H.), Samman-Tahhan, A. (Ayman), Sandesara, P.B. (Pratik B.), Teren, A. (Andrej), Timmis, A. (Adam), Van de Werf, F. (Frans), Wilde, A.A.M. (Arthur), Ford, I. (Ian), Stott, D.J. (David. J.), Algra, A. (Ale), Andreassi, M.G. (Maria G.), Ardissino, D. (Diego), Arsenault, B.J. (Benoit J.), Ballantyne, C. (Christie), Bergmeijer, T.O. (Thomas O.), Bezzina, C.R. (Connie R.), Body, S.C. (Simon C.), Boersma, E.H. (Eric H.), Bogaty, P. (Peter), Bots, M.L. (Michiel), Brenner, H. (Hermann), Brugts, J.J. (Jasper), Burkhardt, R. (Ralph), Carpeggiani, C. (Clara), Condorelli, G. (Gianluigi), Cooper-Dehoff, R.M. (Rhonda), Cresci, S. (Sharon), Danchin, N. (Nicolas), Faire, U. (Ulf) de, Doughty, R.N. (Robert N.), Drexel, H. (Heinz), Engert, J.C. (James C.), Fox, K.A.A. (Keith), Girelli, D. (Domenico), Grobbee, D.E. (Diederick E.), Hagström, E. (Emil), Hazen, S.L. (Stanley), Held, C. (Claes), Hemingway, H., Hoefer, I.E. (Imo), Hovingh, G.K. (G Kees), Jabbari, R. (Reza), Johnson, J.A. (Jennifer ), Jukema, J.W. (Jan Wouter), Kaczor, M.P. (Marcin P.), Kähönen, M. (Mika), Kettner, J. (Jiri), Kiliszek, M. (Marek), Klungel, O.H. (Olaf), Lagerqvist, B. (Bo), Lambrechts, D. (Diether), Laurikka, J.O. (Jari O.), Lehtimäki, T. (Terho), Lindholm, D. (Daniel), Mahmoodi, B.K. (Bakhtawar K.), Maitland-van der Zee, A-H. (Anke-Hilse), McPherson, R. (Ruth), Melander, O. (Olle), Metspalu, A. (Andres), Niemcunowicz-Janica, A. (Anna), Olivieri, O. (Oliviero), Opolski, G. (Grzegorz), Palmer, C.N.A. (Colin), Pasterkamp, G. (Gerard), Pepine, C.J. (Carl), Pereira, A. (A.), Pilote, L. (Louise), Erdmann, J. (Jeanette), Richards, A.M. (A Mark), Sanak, M. (Marek), Siegbahn, A. (Agneta), Simon, T. (Tabassome), Sinisalo, J. (Juha), Smith, J.G. (J Gustav), Schwartz, S.M. (Stephen), Stender, S. (Steen), Stewart, A.F. (Alexandre F.), Szczeklik, W. (Wojciech), Szpakowicz, A. (Anna), Tardif, J.-C. (Jean-Claude), Berg, J.M. (Jurrien) ten, Tfelt-Hansen, J. (Jacob), Thanassoulis, G. (George), Thiery, J.P. (Joachim), Torp-Pedersen, C. (Christian Tobias), Graaf, Y. (Yolanda) van der, Visseren, F.L.J. (Frank), Waltenberger, J. (Johannes), Weeke, P.E. (Peter E.), Harst, P. (Pim) van der, Lang, C.C. (Chim C.), Sattar, N. (Naveed), Cameron, V.A. (Vicky A.), Anderson, J.L. (Jeffrey), Brophy, J.M. (James M.), Pare, G. (Guillame), Horne, B.D. (Benjamin), Ye, S. (Shu), Wallentin, L. (Lars), Wauters, E. (Els), Samani, N.J. (Nilesh), Hingorani, A. (Aroon), Asselbergs, F.W. (Folkert), Patel, R.S. (Riyaz), Tragante, V. (Vinicius), Schmidt, A.F. (Amand), McCubrey, R.O. (Raymond O.), Holmes, M.V. (Michael), Howe, L.J. (Laurence J.), Direk, K. (Kenan), Åkerblom, A. (Axel), Leander, K. (Karin), Virani, S.S. (Salim), Kaminski, K.A. (Karol A.), Muehlschlegel, J.D. (Jochen), Allayee, H. (Hooman), Almgren, P. (Peter), Alver, M. (Maris), Baranova, E.V. (Ekaterina V.), Behloui, H. (Hassan), Boeckx, B. (Bram), Braund, P.S. (Peter), Breitling, L.P. (Lutz), Delgado, G., Duarte, N.E. (Nubia E.), Dubé, G.P. (Gregory), Dufresne, L. (Line), Eriksson, N. (Niclas), Foco, L. (Luisa), Scholz, M. (Markus), Gijsberts, C.M. (Crystel M.), Glinge, C. (Charlotte), Gong, Y. (Yan), Hartiala, J. (Jaana), Heydarpour, M. (Mahyar), Hubacek, J.A. (Jaroslav A.), Kleber, M.E. (Marcus), Kofink, D. (Daniel), Kotti, S. (Salma), Kuukasjärvi, P. (Pekka), Lee, V.-V. (Vei-Vei), Leiherer, A. (Andreas), Lenzini, P.A. (Petra A.), Levin, D. (Daniel), Lyytikäinen, L.-P. (Leo-Pekka), Martinelli, N. (Nicola), Mons, U. (Ute), Nelson, C.P. (Christopher P.), Nikus, K. (Kjell), Pilbrow, A.P. (Anna P.), Ploski, R. (Rafal), Sun, Y.V. (Yan V.), Tanck, M.W.T. (Michael), Tang, W. (W.), Trompet, S. (Stella), van der Laan, S.W. (Sander W.), Setten, J. (Jessica) van, Vilmundarson, R.O. (Ragnar O.), Viviani Anselmi, C. (Chiara), Vlachopoulou, E. (Efthymia), Al Ali, L. (Lawien), Boerwinkle, E.A. (Eric), Briguori, C. (Carlo), Carlquist, J.F. (John), Carruthers, K.F. (Kathryn), Casu, G. (Gavino), Deanfield, J. (John), Deloukas, P. (Panos), Dudbridge, F. (Frank), Engstrøm, T. (Thomas), Fitzpatrick, N. (Natalie), Fox, K.M. (Kim), Gigante, B. (Bruna), James, S.K. (Stefan), Lokki, M.-L. (Marja-Liisa), Lotufo, P.A. (Paulo A.), Marziliano, N. (Nicola), Mordi, I.R. (Ify R.), Muhlestein, J.B. (Joseph), Newton-Cheh, C. (Christopher), Pitha, J. (Jan), Saely, C.H. (Christoph H.), Samman-Tahhan, A. (Ayman), Sandesara, P.B. (Pratik B.), Teren, A. (Andrej), Timmis, A. (Adam), Van de Werf, F. (Frans), Wilde, A.A.M. (Arthur), Ford, I. (Ian), Stott, D.J. (David. J.), Algra, A. (Ale), Andreassi, M.G. (Maria G.), Ardissino, D. (Diego), Arsenault, B.J. (Benoit J.), Ballantyne, C. (Christie), Bergmeijer, T.O. (Thomas O.), Bezzina, C.R. (Connie R.), Body, S.C. (Simon C.), Boersma, E.H. (Eric H.), Bogaty, P. (Peter), Bots, M.L. (Michiel), Brenner, H. (Hermann), Brugts, J.J. (Jasper), Burkhardt, R. (Ralph), Carpeggiani, C. (Clara), Condorelli, G. (Gianluigi), Cooper-Dehoff, R.M. (Rhonda), Cresci, S. (Sharon), Danchin, N. (Nicolas), Faire, U. (Ulf) de, Doughty, R.N. (Robert N.), Drexel, H. (Heinz), Engert, J.C. (James C.), Fox, K.A.A. (Keith), Girelli, D. (Domenico), Grobbee, D.E. (Diederick E.), Hagström, E. (Emil), Hazen, S.L. (Stanley), Held, C. (Claes), Hemingway, H., Hoefer, I.E. (Imo), Hovingh, G.K. (G Kees), Jabbari, R. (Reza), Johnson, J.A. (Jennifer ), Jukema, J.W. (Jan Wouter), Kaczor, M.P. (Marcin P.), Kähönen, M. (Mika), Kettner, J. (Jiri), Kiliszek, M. (Marek), Klungel, O.H. (Olaf), Lagerqvist, B. (Bo), Lambrechts, D. (Diether), Laurikka, J.O. (Jari O.), Lehtimäki, T. (Terho), Lindholm, D. (Daniel), Mahmoodi, B.K. (Bakhtawar K.), Maitland-van der Zee, A-H. (Anke-Hilse), McPherson, R. (Ruth), Melander, O. (Olle), Metspalu, A. (Andres), Niemcunowicz-Janica, A. (Anna), Olivieri, O. (Oliviero), Opolski, G. (Grzegorz), Palmer, C.N.A. (Colin), Pasterkamp, G. (Gerard), Pepine, C.J. (Carl), Pereira, A. (A.), Pilote, L. (Louise), Erdmann, J. (Jeanette), Richards, A.M. (A Mark), Sanak, M. (Marek), Siegbahn, A. (Agneta), Simon, T. (Tabassome), Sinisalo, J. (Juha), Smith, J.G. (J Gustav), Schwartz, S.M. (Stephen), Stender, S. (Steen), Stewart, A.F. (Alexandre F.), Szczeklik, W. (Wojciech), Szpakowicz, A. (Anna), Tardif, J.-C. (Jean-Claude), Berg, J.M. (Jurrien) ten, Tfelt-Hansen, J. (Jacob), Thanassoulis, G. (George), Thiery, J.P. (Joachim), Torp-Pedersen, C. (Christian Tobias), Graaf, Y. (Yolanda) van der, Visseren, F.L.J. (Frank), Waltenberger, J. (Johannes), Weeke, P.E. (Peter E.), Harst, P. (Pim) van der, Lang, C.C. (Chim C.), Sattar, N. (Naveed), Cameron, V.A. (Vicky A.), Anderson, J.L. (Jeffrey), Brophy, J.M. (James M.), Pare, G. (Guillame), Horne, B.D. (Benjamin), Ye, S. (Shu), Wallentin, L. (Lars), Wauters, E. (Els), Samani, N.J. (Nilesh), Hingorani, A. (Aroon), and Asselbergs, F.W. (Folkert)
Abstract: BACKGROUND: The Genetics of Subsequent Coronary Heart Disease (GENIUS-CHD) consortium was established to facilitate discovery and validation of genetic variants a
Published: 2019
Full Text: View/download PDF

5. Erratum to: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Author: Evangelou, E. (Evangelos), Warren, H. (Helen), Mosen-Ansorena, D. (David), Mifsud, B. (Borbala), Pazoki, R. (Raha), Gao, H. (He), Ntritsos, G. (Georgios), Dimou, N. (Niki), Cabrera, C.P. (Claudia P.), Karaman, I. (Ibrahim), Ng, F.L. (Fu Liang), Evangelou, M. (Marina), Witkowska, K. (Katarzyna), Tzanis, E. (Evan), Hellwege, J.N. (Jacklyn N.), Giri, A. (Ayush), Velez Edwards, D.R. (Digna R.), Sun, Y.V. (Yan V.), Cho, K. (Kelly), Gaziano, J.M. (J. Michael), Wilson, P.W.F. (Peter W. F.), Tsao, P.S. (Philip S.), Kovesdy, C.P. (Csaba P.), Esko, T. (Tonu), Mägi, R. (Reedik), Milani, L. (Lili), Almgren, P. (Peter), Boutin, T. (Thibaud), Debette, S. (Stéphanie), Ding, J. (Jun), Giulianini, F. (Franco), Holliday, E.G. (Elizabeth), Jackson, A.U. (Anne), Li-Gao, R. (Ruifang), Lin, W.-Y. (Wei-Yu), Luan, J., Mangino, M. (Massimo), Oldmeadow, C. (Christopher), Prins, B.P. (Bram Peter), Qian, Y. (Yong), Sargurupremraj, M. (Muralidharan), Shah, N. (Nisha), Surendran, P. (Praveen), Thériault, S. (Sébastien), Verweij, N. (Niek), Willems, S.M. (Sara), Zhao, J.-H. (Jing-Hua), Amouyel, P. (Philippe), Connell, J. (John), Mutsert, R. (Reneé) de, Doney, A.S.F. (Alex), Farrall, M. (Martin), Menni, C. (Cristina), Morris, A.D. (Andrew), Noordam, R. (Raymond), Pare, G. (Guillame), Poulter, N.R. (Neil), Shields, D.C. (Denis C.), Stanton, A. (Alice), McG Thom, S.A., Abecasis, G. (Gonçalo), Amin, N. (Najaf), Arking, D.E. (Dan), Ayers, K.L. (Kristin), Barbieri, C.M. (Caterina M.), Batini, C. (Chiara), Bis, J.C. (Joshua), Blake, T. (Tineka), Bochud, M. (Murielle), Boehnke, M. (Michael), Boerwinkle, E. (Eric), Boomsma, D.I. (Dorret I.), Bottinger, E.P. (Erwin P.), Braund, P.S. (Peter), Brumat, M. (Marco), Campbell, A. (Archie), Campbell, H. (Harry), Chakravarti, A. (Aravinda), Chambers, J.C. (John C.), Chauhan, G. (Ganesh), Ciullo, M. (Marina), Cocca, M. (Massimiliano), Collins, F. (Francis), Cordell, H.J. (Heather), Davies, G. (Gail), de Borst, M.H. (Martin H.), Geus, E.J.C. (Eco) de, Deary, I.J. (Ian), Deelen, J. (Joris), Del Greco M, F. (Fabiola), Demirkale, C.Y. (Cumhur Yusuf), Dörr, M. (Marcus), Ehret, G.B. (Georg B.), Elosua, R. (Roberto), Enroth, S. (Stefan), Erzurumluoglu, A.M. (A. Mesut), Ferreira, T. (Teresa), Frånberg, M. (Mattias), Franco, O.H. (Oscar), Gandin, I. (Ilaria), Gasparini, P. (Paolo), Giedraitis, V. (Vilmantas), Gieger, C. (Christian), Girotto, G. (Giorgia), Goel, A. (Anuj), Gow, A.J. (Alan J.), Gudnason, V. (Vilmundur), Guo, X. (Xiuqing), Gyllensten, U. (Ulf), Hamsten, A. (Anders), Harris, T.B. (Tamara), Harris, S.E. (Sarah), Hartman, C.A. (Catharina A.), Havulinna, A.S. (Aki), Hicks, A.A. (Andrew A.), Hofer, E. (Edith), Hofman, A. (Albert), Hottenga, J.J. (Jouke Jan), Huffman, J.E. (Jennifer E.), Hwang, S.-J. (Shih-Jen), Ingelsson, E. (Erik), James, A. (Alan), Jansen, R. (Rick), Jarvelin, M.-R. (Marjo-Riitta), Joehanes, R. (Roby), Johansson, A. (Åsa), Johnson, A.D. (Andrew), Joshi, P.K. (Peter K.), Jousilahti, P. (Pekka), Jukema, J.W. (Jan Wouter), Jula, A. (Antti), Kähönen, M. (Mika), Kathiresan, S. (Sekar), Keavney, B.D. (Bernard D.), Khaw, K.-T. (Kay-Tee), Knekt, P., Knight, J. (Joanne), Kolcic, I. (Ivana), Kooner, J.S. (Jaspal S.), Koskinen, S. (Seppo), Kristiansson, K. (Kati), Kutalik, Z. (Zoltán), Laan, M. (Maris), Larson, M.G. (Martin), Launer, L.J. (Lenore), Lehne, B. (Benjamin), Lehtimäki, T. (Terho), Liewald, D.C.M. (David C. M.), Lin, L. (Li), Kao, W.H.L. (Wen), Lindgren, C.M. (Cecilia M.), Liu, Y. (YongMei), Loos, R.J.F. (Ruth), Lopez, L.M. (Lorna), Lu, Y. (Yingchang), Lyytikäinen, L.-P. (Leo-Pekka), Mahajan, A. (Anubha), Mamasoula, C. (Chrysovalanto), Marrugat, J. (Jaume), Marten, J. (Jonathan), Milaneschi, Y. (Yuri), Morgan, A. (Anna), Morris, A.P. (Andrew), Morrison, A.C. (Alanna), Munson, P.J. (Peter), Nalls, M.A. (Michael), Nandakumar, P. (Priyanka), Nelson, C.P. (Christopher P.), Niiranen, T. (Teemu), Nolte, I.M. (Ilja), Nutile, T. (Teresa), Oldehinkel, A.J. (Albertine), Oostra, B.A. (Ben), O’Reilly, P.F. (Paul F.), Org, E. (Elin), Padmanabhan, S. (Sandosh), Palmas, W. (Walter), Palotie, A. (Aarno), Pattie, A. (Alison), Penninx, B.W.J.H. (Brenda), Perola, M. (Markus), Peters, A. (Annette), Polasek, O. (Ozren), Pramstaller, P.P. (Peter Paul), Nguyen, Q.T. (Quang Tri), Raitakari, O. (Olli), Ren, M. (Meixia), Rettig, R. (Rainer), Rice, K.M. (Kenneth), Ridker, P.M. (Paul), Ried, J.S. (Janina S.), Riese, H. (Harriëtte), Ripatti, S. (Samuli), Robino, A. (Antonietta), Rose, L.M. (Lynda M.), Rotter, J.I. (Jerome I.), Rudan, I. (Igor), Ruggiero, D., Saba, Y. (Yasaman), Sala, C. (Cinzia), Salomaa, V. (Veikko), Samani, N.J. (Nilesh J.), Sarin, A.-P., Schmidt, R. (Reinhold), Schmidt, H. (Helena), Shrine, N.R.G. (Nick), Siscovick, D. (David), Smith, A.V. (Albert), Snieder, H. (Harold), Sõber, S. (Siim), Sorice, R., Starr, J.M. (John), Stott, D.J. (David. J.), Strachan, D.P. (David), Strawbridge, R.J. (Rona), Sundström, J. (Johan), Swertz, M.A. (Morris A.), Taylor, K.D. (Kent), Teumer, A. (Alexander), Tobin, M.D. (Martin), Tomaszewski, M. (Maciej), Toniolo, D. (Daniela), Traglia, M. (Michela), Trompet, S. (Stella), Tuomilehto, J. (Jaakko), Tzourio, C. (Christophe), Uitterlinden, A.G. (André), Vaez, A. (Ahmad), Most, P.J. (Peter) van der, Duijn, C.M. (Cornelia) van, Vergnaud, A.-C. (Anne-Claire), Verwoert, G.C. (Germaine C.), Vitart, V. (Veronique), Völker, U. (Uwe), Vollenweider, P. (Peter), Vuckovic, D. (Dragana), Watkins, H. (Hugh), Wild, S.H. (Sarah), Willemsen, G. (Gonneke), Wilson, J.F. (James F.), Wright, A.F. (Alan), Yao, J. (Jie), Zemunik, T. (Tatijana), Zhang, W. (Weihua), Attia, J. (John), Butterworth, A.S. (Adam S.), Chasman, D.I. (Daniel), Conen, D. (David), Cucca, F. (Francesco), Danesh, J. (John), Hayward, C. (Caroline), Howson, J.M.M. (Joanna M. M.), Laakso, M. (Markku), Lakatta, E.G. (Edward G.), Langenberg, C. (Claudia), Melander, O. (Olle), Mook-Kanamori, D.O. (Dennis O.), Palmer, C.N.A. (Colin N. A.), Risch, L. (Lorenz), Scott, R.A. (Robert), Scott, R.J. (Rodney J.), Sever, P. (Peter), Spector, T.D. (Timothy), van der Harst, P. (Pim), Wareham, N.J. (Nick), Zeggini, E. (Eleftheria), Levy, D. (Daniel), Munroe, P. (Patricia), Newton-Cheh, C. (Christopher), Brown, M.J. (Morris), Metspalu, A. (Andres), Hung, A.M. (Adriana M.), Ódonnell, C.J. (Christopher), Edwards, T.L. (Todd L.), Psaty, B.M. (Bruce), Tzoulaki, I., Barnes, M.J. (Michael), Wain, L.V. (Louise V.), Elliott, P. (Paul), Caulfield, M. (Mark), Evangelou, E. (Evangelos), Warren, H. (Helen), Mosen-Ansorena, D. (David), Mifsud, B. (Borbala), Pazoki, R. (Raha), Gao, H. (He), Ntritsos, G. (Georgios), Dimou, N. (Niki), Cabrera, C.P. (Claudia P.), Karaman, I. (Ibrahim), Ng, F.L. (Fu Liang), Evangelou, M. (Marina), Witkowska, K. (Katarzyna), Tzanis, E. (Evan), Hellwege, J.N. (Jacklyn N.), Giri, A. (Ayush), Velez Edwards, D.R. (Digna R.), Sun, Y.V. (Yan V.), Cho, K. (Kelly), Gaziano, J.M. (J. Michael), Wilson, P.W.F. (Peter W. F.), Tsao, P.S. (Philip S.), Kovesdy, C.P. (Csaba P.), Esko, T. (Tonu), Mägi, R. (Reedik), Milani, L. (Lili), Almgren, P. (Peter), Boutin, T. (Thibaud), Debette, S. (Stéphanie), Ding, J. (Jun), Giulianini, F. (Franco), Holliday, E.G. (Elizabeth), Jackson, A.U. (Anne), Li-Gao, R. (Ruifang), Lin, W.-Y. (Wei-Yu), Luan, J., Mangino, M. (Massimo), Oldmeadow, C. (Christopher), Prins, B.P. (Bram Peter), Qian, Y. (Yong), Sargurupremraj, M. (Muralidharan), Shah, N. (Nisha), Surendran, P. (Praveen), Thériault, S. (Sébastien), Verweij, N. (Niek), Willems, S.M. (Sara), Zhao, J.-H. (Jing-Hua), Amouyel, P. (Philippe), Connell, J. (John), Mutsert, R. (Reneé) de, Doney, A.S.F. (Alex), Farrall, M. (Martin), Menni, C. (Cristina), Morris, A.D. (Andrew), Noordam, R. (Raymond), Pare, G. (Guillame), Poulter, N.R. (Neil), Shields, D.C. (Denis C.), Stanton, A. (Alice), McG Thom, S.A., Abecasis, G. (Gonçalo), Amin, N. (Najaf), Arking, D.E. (Dan), Ayers, K.L. (Kristin), Barbieri, C.M. (Caterina M.), Batini, C. (Chiara), Bis, J.C. (Joshua), Blake, T. (Tineka), Bochud, M. (Murielle), Boehnke, M. (Michael), Boerwinkle, E. (Eric), Boomsma, D.I. (Dorret I.), Bottinger, E.P. (Erwin P.), Braund, P.S. (Peter), Brumat, M. (Marco), Campbell, A. (Archie), Campbell, H. (Harry), Chakravarti, A. (Aravinda), Chambers, J.C. (John C.), Chauhan, G. (Ganesh), Ciullo, M. (Marina), Cocca, M. (Massimiliano), Collins, F. (Francis), Cordell, H.J. (Heather), Davies, G. (Gail), de Borst, M.H. (Martin H.), Geus, E.J.C. (Eco) de, Deary, I.J. (Ian), Deelen, J. (Joris), Del Greco M, F. (Fabiola), Demirkale, C.Y. (Cumhur Yusuf), Dörr, M. (Marcus), Ehret, G.B. (Georg B.), Elosua, R. (Roberto), Enroth, S. (Stefan), Erzurumluoglu, A.M. (A. Mesut), Ferreira, T. (Teresa), Frånberg, M. (Mattias), Franco, O.H. (Oscar), Gandin, I. (Ilaria), Gasparini, P. (Paolo), Giedraitis, V. (Vilmantas), Gieger, C. (Christian), Girotto, G. (Giorgia), Goel, A. (Anuj), Gow, A.J. (Alan J.), Gudnason, V. (Vilmundur), Guo, X. (Xiuqing), Gyllensten, U. (Ulf), Hamsten, A. (Anders), Harris, T.B. (Tamara), Harris, S.E. (Sarah), Hartman, C.A. (Catharina A.), Havulinna, A.S. (Aki), Hicks, A.A. (Andrew A.), Hofer, E. (Edith), Hofman, A. (Albert), Hottenga, J.J. (Jouke Jan), Huffman, J.E. (Jennifer E.), Hwang, S.-J. (Shih-Jen), Ingelsson, E. (Erik), James, A. (Alan), Jansen, R. (Rick), Jarvelin, M.-R. (Marjo-Riitta), Joehanes, R. (Roby), Johansson, A. (Åsa), Johnson, A.D. (Andrew), Joshi, P.K. (Peter K.), Jousilahti, P. (Pekka), Jukema, J.W. (Jan Wouter), Jula, A. (Antti), Kähönen, M. (Mika), Kathiresan, S. (Sekar), Keavney, B.D. (Bernard D.), Khaw, K.-T. (Kay-Tee), Knekt, P., Knight, J. (Joanne), Kolcic, I. (Ivana), Kooner, J.S. (Jaspal S.), Koskinen, S. (Seppo), Kristiansson, K. (Kati), Kutalik, Z. (Zoltán), Laan, M. (Maris), Larson, M.G. (Martin), Launer, L.J. (Lenore), Lehne, B. (Benjamin), Lehtimäki, T. (Terho), Liewald, D.C.M. (David C. M.), Lin, L. (Li), Kao, W.H.L. (Wen), Lindgren, C.M. (Cecilia M.), Liu, Y. (YongMei), Loos, R.J.F. (Ruth), Lopez, L.M. (Lorna), Lu, Y. (Yingchang), Lyytikäinen, L.-P. (Leo-Pekka), Mahajan, A. (Anubha), Mamasoula, C. (Chrysovalanto), Marrugat, J. (Jaume), Marten, J. (Jonathan), Milaneschi, Y. (Yuri), Morgan, A. (Anna), Morris, A.P. (Andrew), Morrison, A.C. (Alanna), Munson, P.J. (Peter), Nalls, M.A. (Michael), Nandakumar, P. (Priyanka), Nelson, C.P. (Christopher P.), Niiranen, T. (Teemu), Nolte, I.M. (Ilja), Nutile, T. (Teresa), Oldehinkel, A.J. (Albertine), Oostra, B.A. (Ben), O’Reilly, P.F. (Paul F.), Org, E. (Elin), Padmanabhan, S. (Sandosh), Palmas, W. (Walter), Palotie, A. (Aarno), Pattie, A. (Alison), Penninx, B.W.J.H. (Brenda), Perola, M. (Markus), Peters, A. (Annette), Polasek, O. (Ozren), Pramstaller, P.P. (Peter Paul), Nguyen, Q.T. (Quang Tri), Raitakari, O. (Olli), Ren, M. (Meixia), Rettig, R. (Rainer), Rice, K.M. (Kenneth), Ridker, P.M. (Paul), Ried, J.S. (Janina S.), Riese, H. (Harriëtte), Ripatti, S. (Samuli), Robino, A. (Antonietta), Rose, L.M. (Lynda M.), Rotter, J.I. (Jerome I.), Rudan, I. (Igor), Ruggiero, D., Saba, Y. (Yasaman), Sala, C. (Cinzia), Salomaa, V. (Veikko), Samani, N.J. (Nilesh J.), Sarin, A.-P., Schmidt, R. (Reinhold), Schmidt, H. (Helena), Shrine, N.R.G. (Nick), Siscovick, D. (David), Smith, A.V. (Albert), Snieder, H. (Harold), Sõber, S. (Siim), Sorice, R., Starr, J.M. (John), Stott, D.J. (David. J.), Strachan, D.P. (David), Strawbridge, R.J. (Rona), Sundström, J. (Johan), Swertz, M.A. (Morris A.), Taylor, K.D. (Kent), Teumer, A. (Alexander), Tobin, M.D. (Martin), Tomaszewski, M. (Maciej), Toniolo, D. (Daniela), Traglia, M. (Michela), Trompet, S. (Stella), Tuomilehto, J. (Jaakko), Tzourio, C. (Christophe), Uitterlinden, A.G. (André), Vaez, A. (Ahmad), Most, P.J. (Peter) van der, Duijn, C.M. (Cornelia) van, Vergnaud, A.-C. (Anne-Claire), Verwoert, G.C. (Germaine C.), Vitart, V. (Veronique), Völker, U. (Uwe), Vollenweider, P. (Peter), Vuckovic, D. (Dragana), Watkins, H. (Hugh), Wild, S.H. (Sarah), Willemsen, G. (Gonneke), Wilson, J.F. (James F.), Wright, A.F. (Alan), Yao, J. (Jie), Zemunik, T. (Tatijana), Zhang, W. (Weihua), Attia, J. (John), Butterworth, A.S. (Adam S.), Chasman, D.I. (Daniel), Conen, D. (David), Cucca, F. (Francesco), Danesh, J. (John), Hayward, C. (Caroline), Howson, J.M.M. (Joanna M. M.), Laakso, M. (Markku), Lakatta, E.G. (Edward G.), Langenberg, C. (Claudia), Melander, O. (Olle), Mook-Kanamori, D.O. (Dennis O.), Palmer, C.N.A. (Colin N. A.), Risch, L. (Lorenz), Scott, R.A. (Robert), Scott, R.J. (Rodney J.), Sever, P. (Peter), Spector, T.D. (Timothy), van der Harst, P. (Pim), Wareham, N.J. (Nick), Zeggini, E. (Eleftheria), Levy, D. (Daniel), Munroe, P. (Patricia), Newton-Cheh, C. (Christopher), Brown, M.J. (Morris), Metspalu, A. (Andres), Hung, A.M. (Adriana M.), Ódonnell, C.J. (Christopher), Edwards, T.L. (Todd L.), Psaty, B.M. (Bruce), Tzoulaki, I., Barnes, M.J. (Michael), Wain, L.V. (Louise V.), Elliott, P. (Paul), and Caulfield, M. (Mark)
Abstract: In the version of this article originally published, the name of author Martin H. de Borst was coded incorrectly in the XML. The error has now been corrected in the HTML version of the paper.
Published: 2018
Full Text: View/download PDF

6. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Author: UCL - SSS/IREC/NEFR - Pôle de Néphrologie, UCL - (SLuc) Service de néphrologie, Pattaro, C., Teumer, A., Gorski, M., Chu, A.Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M.-H., Pers, T.H., Johnson, A.D., Ko, Y.-A., Fuchsberger, C., Tayo, B., Nalls, M., Feitosa, M.F., Isaacs, A., Dehghan, A., D'Adamo, P., Adeyemo, A., Dieffenbach, A.K., Zonderman, A.B., Nolte, I.M., Van Der Most, P.J., Wright, A.F., Shuldiner, A.R., Morrison, A.C., Hofman, A., Smith, A.V., Dreisbach, A.W., Franke, A., Uitterlinden, A.G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, Å., Demirkan, A., Kollerits, B., Freedman, B.I., Ponte, B., Oostra, B.A., Paulweber, B., Krämer, B.K., Mitchell, B.D., Buckley, B.M., Peralta, C.A., Hayward, C., Helmer, C., Rotimi, C.N., Shaffer, C.M., Müller, C., Sala, C., Van Duijn, C.M., Saint-Pierre, A., Ackermann, D., Shriner, D., Ruggiero, D., Toniolo, D., Lu, Y., Cusi, D., Czamara, D., Ellinghaus, D., Siscovick, D.S., Ruderfer, D., Gieger, C., Grallert, H., Rochtchina, E., Atkinson, E.J., Holliday, E.G., Boerwinkle, E., Salvi, E., Bottinger, E.P., Murgia, F., Rivadeneira, F., Ernst, F., Kronenberg, F., Hu, F.B., Navis, G.J., Curhan, G.C., Ehret, G.B., Homuth, G., Coassin, S., Thun, G.-A., Pistis, G., Gambaro, G., Malerba, G., Montgomery, G.W., Eiriksdottir, G., Jacobs, G., Li, G., Wichmann, H.-E., Campbell, H., Schmidt, H., Wallaschofski, H., Völzke, H., Brenner, H., Kroemer, H.K., Kramer, H., Lin, H., Leach, I.M., Ford, I., Guessous, I., Rudan, I., Prokopenko, I., Borecki, I., Heid, I.M., Kolcic, I., Persico, I., Jukema, J.W., Wilson, J.F., Felix, J.F., Divers, J., Lambert, J.-C., Stafford, J.M., Gaspoz, J.-M., Smith, J.A., Faul, J.D., Wang, J.J., Ding, J., Hirschhorn, J.N., Attia, J., Whitfield, J.B., Chalmers, J., Viikari, J., Coresh, J., Denny, J.C., Karjalainen, J., Fernandes, J.K., Endlich, K., Butterbach, K., Keene, K.L., Lohman, K., Portas, L., Launer, L.J., Lyytikäinen, L.-P., Yengo, L., Franke, L., Ferrucci, L., Rose, L.M., Kedenko, L., Rao, M., Struchalin, M., Kleber, M.E., Cavalieri, M., Haun, M., Cornelis, M.C., Ciullo, M., Pirastu, M., De Andrade, M., McEvoy, M.A., Woodward, M., Adam, M., Cocca, M., Nauck, M., Imboden, M., Waldenberger, M., Pruijm, M., Metzger, M., Stumvoll, M., Evans, M.K., Sale, M.M., Kähönen, M., Boban, M., Bochud, M., Rheinberger, M., Verweij, N., Bouatia-Naji, N., Martin, N.G., Hastie, N., Probst-Hensch, N., Soranzo, N., Devuyst, O., Raitakari, O., Gottesman, O., Franco, O.H., Polasek, O., Gasparini, P., Munroe, P.B., Ridker, P.M., Mitchell, P., Muntner, P., Meisinger, C., Smit, J.H., Abecasis, G.R., Adair, L.S., Alexander, M., Altshuler, D., Amin, N., Arking, D.E., Arora, P., Aulchenko, Y., Bakker, S.J.L., Bandinelli, S., Barroso, I., Beckmann, J.S., Beilby, J.P., Bergman, R.N., Bergmann, S., Bis, J.C., Boehnke, M., Bonnycastle, L.L., Bornstein, S.R., Bots, M.L., Bragg-Gresham, J.L., Brand, S.-M., Brand, E., Braund, P.S., Brown, M.J., Burton, P.R., Casas, J.P., Caulfield, M.J., Chakravarti, A., Chambers, J.C., Chandak, G.R., Chang, Y.-P.C., Charchar, F.J., Chaturvedi, N., Cho, Y.S., Clarke, R., Collins, F.S., Collins, R., Connell, J.M., Cooper, J.A., Cooper, M.N., Cooper, R.S., Corsi, A.M., Dörr, M., Dahgam, S., Danesh, J., Smith, G.D., Day, I.N.M., Deloukas, P., Denniff, M., Dominiczak, A.F., Dong, Y., Doumatey, A., Elliott, P., Elosua, R., Erdmann, J., Eyheramendy, S., Farrall, M., Fava, C., Forrester, T., Fowkes, F.G.R., Fox, E.R., Frayling, T.M., Galan, P., Ganesh, S.K., Garcia, M., Gaunt, T.R., Glazer, N.L., Go, M.J., Goel, A., Grässler, J., Grobbee, D.E., Groop, L., Guarrera, S., Guo, X., Hadley, D., Hamsten, A., Han, B.-G., Hardy, R., Hartikainen, A.-L., Heath, S., Heckbert, S.R., Hedblad, B., Hercberg, S., Hernandez, D., Hicks, A.A., Hilton, G., Hingorani, A.D., Hoffman Bolton, J.A., Hopewell, J.C., Howard, P., Humphries, S.E., Hunt, S.C., Hveem, K., Ikram, M.A., Islam, M., Iwai, N., Jarvelin, M.-R., Jackson, A.U., Jafar, T.H., Janipalli, C.S., Johnson, T., Kathiresan, S., Khaw, K.-T., Kim, H.-L., Kinra, S., Kita, Y., Kivimaki, M., Kooner, J.S., Kumar, M.J.K., Kuh, D., Kulkarni, S.R., Kumari, M., Kuusisto, J., Kuznetsova, T., Laakso, M., Laan, M., Laitinen, J., Lakatta, E.G., Langefeld, C.D., Larson, M.G., Lathrop, M., Lawlor, D.A., Lawrence, R.W., Lee, J.-Y., Lee, N.R., Levy, D., Longstreth, W.T., Luan, J., Lucas, G., Ludwig, B., Mangino, M., Mani, K.R., Marmot, M.G., Mattace-Raso, F.U.S., Matullo, G., McArdle, W.L., McKenzie, C.A., Meitinger, T., Melander, O., Meneton, P., Meschia, J.F., Miki, T., Milaneschi, Y., Mohlke, K.L., Mooser, V., Morken, M.A., Morris, R.W., Mosley, T.H., Najjar, S., Narisu, N., Newton-Cheh, C., Nguyen, K.-D.H., Nilsson, P., Nyberg, F., O'Donnell, C.J., Ogihara, T., Ohkubo, T., Okamura, T., Ong, R.T.-H., Ongen, H., Onland-Moret, N.C., O'Reilly, P.F., Org, E., Orru, M., Palmas, W., Palmen, J., Palmer, L.J., Palmer, N.D., Parker, A.N., Peden, J.F., Peltonen, L., Perola, M., Pihur, V., Platou, C.G.P., Plump, A., Prabhakaran, D., Psaty, B.M., Raffel, L.J., Rao, D.C., Rasheed, A., Ricceri, F., Rice, K.M., Rosengren, A., Rotter, J.I., Rudock, M.E., Sõber, S., Salako, T., Saleheen, D., Salomaa, V., Samani, N.J., Schwartz, S.M., Schwarz, P.E.H., Scott, L.J., Scott, J., Scuteri, A., Sehmi, J.S., Seielstad, M., Seshadri, S., Sharma, P., Shaw-Hawkins, S., Shi, G., Shrine, N.R.G., Sijbrands, E.J.G., Sim, X., Singleton, A., Sjögren, M., Smith, N.L., Artigas, M.S., Spector, T.D., Staessen, J.A., Stancakova, A., Steinle, N.I., Strachan, D.P., Stringham, H.M., Sun, Y.V., Swift, A.J., Tabara, Y., Tai, E.-S., Talmud, P.J., Taylor, A., Terzic, J., Thelle, D.S., Tobin, M.D., Tomaszewski, M., Tripathy, V., Tuomilehto, J., Tzoulaki, I., Uda, M., Ueshima, H., Uiterwaal, C.S.P.M., Umemura, S., Van Der Harst, P., Van Der Schouw, Y.T., Van Gilst, W.H., Vartiainen, E., Vasan, R.S., Veldre, G., Verwoert, G.C., Viigimaa, M., Vinay, D.G., Vineis, P., Voight, B.F., Vollenweider, P., Wagenknecht, L.E., Wain, L.V., Wang, X., Wang, T.J., Wareham, N.J., Watkins, H., Weder, A.B., Whincup, P.H., Wiggins, K.L., Witteman, J.C.M., Wong, A., Wu, Y., Yajnik, C.S., Yao, J., Young, J.H., Zelenika, D., Zhai, G., Zhang, W., Zhang, F., Zhao, J.H., Zhu, H., Zhu, X., Zitting, P., Zukowska-Szczechowska, E., Okada, Y., Wu, J.-Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S.-C., Wong, T.-Y., Liu, J., Young, T.L., Aung, T., Teo, Y.-Y., Kim, Y.J., Kang, D., Chen, C.-H., Tsai, F.-J., Chang, L.-C., Fann, S.-J.C., Mei, H., Hixson, J.E., Chen, S., Katsuya, T., Isono, M., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y.-T., Tanaka, T., Reilly, M.P., Schunkert, H., Assimes, T.L., Hall, A., Hengstenberg, C., König, I.R., Laaksonen, R., McPherson, R., Thompson, J.R., Thorsteinsdottir, U., Ziegler, A., Absher, D., Chen, L., Cupples, L.A., Halperin, E., Musunuru, K., Preuss, M., Schillert, A., Thorleifsson, G., Wells, G.A., Holm, H., Roberts, R., Stewart, A.F.R., Fortmann, S., Go, A., Hlatky, M., Iribarren, C., Knowles, J., Myers, R., Quertermous, T., Sidney, S., Risch, N., Tang, H., Blankenberg, S., Schnabel, R., Sinning, C., Lackner, K.J., Tiret, L., Nicaud, V., Cambien, F., Bickel, C., Rupprecht, H.J., Perret, C., Proust, C., Münzel, T.F., Barbalic, M., Chen, I.Y.-D., Demissie-Banjaw, S., Folsom, A., Lumley, T., Marciante, K., Taylor, K.D., Volcik, K., Gretarsdottir, S., Gulcher, J.R., Kong, A., Stefansson, K., Thorgeirsson, G., Andersen, K., Fischer, M., Grosshennig, A., Linsel-Nitschke, P., Stark, K., Schreiber, S., Aherrahrou, Z., Bruse, P., Doering, A., Klopp, N., Diemert, P., Loley, C., Medack, A., Nahrstedt, J., Peters, A., Wagner, A.K., Willenborg, C., Böhm, B.O., Dobnig, H., Grammer, T.B., Hoffmann, M.M., Meinitzer, A., Winkelmann, B.R., Pilz, S., Renner, W., Scharnagl, H., Stojakovic, T., Tomaschitz, A., Winkler, K., Guiducci, C., Burtt, N., Gabriel, S.B., Dandona, S., Jarinova, O., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H.H., Devaney, J., Burnett, M.S., Pichard, A.D., Kent, K.M., Satler, L., Lindsay, J.M., Waksman, R., Knouff, C.W., Waterworth, D.M., Walker, M.C., Epstein, S.E., Rader, D.J., Nelson, C.P., Wright, B.J., Balmforth, A.J., Ball, S.G., Loehr, L.R., Rosamond, W.D., Benjamin, E., Haritunians, T., Couper, D., Murabito, J., Wang, Y.A., Stricker, B.H., Chang, P.P., Willerson, J.T., Felix, S.B., Watzinger, N., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R.J., Greiser, K.H., Deckers, J.W., Stritzke, J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M.M., Werdan, K., Mitchell, G.F., Arnett, D.K., Gottdiener, J.S., Blettner, M., Friedrich, N., Kovacs, P., Wild, P.S., Froguel, P., Rettig, R., Mägi, R., Biffar, R., Schmidt, R., Middelberg, R.P.S., Carroll, R.J., Penninx, B.W., Scott, R.J., Katz, R., Sedaghat, S., Wild, S.H., Kardia, S.L.R., Ulivi, S., Hwang, S.-J., Enroth, S., Kloiber, S., Trompet, S., Stengel, B., Hancock, S.J., Turner, S.T., Rosas, S.E., Stracke, S., Harris, T.B., Zeller, T., Zemunik, T., Lehtimäki, T., Illig, T., Aspelund, T., Nikopensius, T., Esko, T., Gyllensten, U., Völker, U., Emilsson, V., Vitart, V., Aalto, V., Gudnason, V., Chouraki, V., Chen, W.-M., Igl, W., März, W., Koenig, W., Lieb, W., Loos, R.J.F., Liu, Y., Snieder, H., Pramstaller, P.P., Parsa, A., O'Connell, J.R., Susztak, K., Hamet, P., Tremblay, J., De Boer, I.H., Böger, C.A., Goessling, W., Chasman, D.I., Köttgen, A., Kao, W.H.L., Fox, C.S., UCL - SSS/IREC/NEFR - Pôle de Néphrologie, UCL - (SLuc) Service de néphrologie, Pattaro, C., Teumer, A., Gorski, M., Chu, A.Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M.-H., Pers, T.H., Johnson, A.D., Ko, Y.-A., Fuchsberger, C., Tayo, B., Nalls, M., Feitosa, M.F., Isaacs, A., Dehghan, A., D'Adamo, P., Adeyemo, A., Dieffenbach, A.K., Zonderman, A.B., Nolte, I.M., Van Der Most, P.J., Wright, A.F., Shuldiner, A.R., Morrison, A.C., Hofman, A., Smith, A.V., Dreisbach, A.W., Franke, A., Uitterlinden, A.G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, Å., Demirkan, A., Kollerits, B., Freedman, B.I., Ponte, B., Oostra, B.A., Paulweber, B., Krämer, B.K., Mitchell, B.D., Buckley, B.M., Peralta, C.A., Hayward, C., Helmer, C., Rotimi, C.N., Shaffer, C.M., Müller, C., Sala, C., Van Duijn, C.M., Saint-Pierre, A., Ackermann, D., Shriner, D., Ruggiero, D., Toniolo, D., Lu, Y., Cusi, D., Czamara, D., Ellinghaus, D., Siscovick, D.S., Ruderfer, D., Gieger, C., Grallert, H., Rochtchina, E., Atkinson, E.J., Holliday, E.G., Boerwinkle, E., Salvi, E., Bottinger, E.P., Murgia, F., Rivadeneira, F., Ernst, F., Kronenberg, F., Hu, F.B., Navis, G.J., Curhan, G.C., Ehret, G.B., Homuth, G., Coassin, S., Thun, G.-A., Pistis, G., Gambaro, G., Malerba, G., Montgomery, G.W., Eiriksdottir, G., Jacobs, G., Li, G., Wichmann, H.-E., Campbell, H., Schmidt, H., Wallaschofski, H., Völzke, H., Brenner, H., Kroemer, H.K., Kramer, H., Lin, H., Leach, I.M., Ford, I., Guessous, I., Rudan, I., Prokopenko, I., Borecki, I., Heid, I.M., Kolcic, I., Persico, I., Jukema, J.W., Wilson, J.F., Felix, J.F., Divers, J., Lambert, J.-C., Stafford, J.M., Gaspoz, J.-M., Smith, J.A., Faul, J.D., Wang, J.J., Ding, J., Hirschhorn, J.N., Attia, J., Whitfield, J.B., Chalmers, J., Viikari, J., Coresh, J., Denny, J.C., Karjalainen, J., Fernandes, J.K., Endlich, K., Butterbach, K., Keene, K.L., Lohman, K., Portas, L., Launer, L.J., Lyytikäinen, L.-P., Yengo, L., Franke, L., Ferrucci, L., Rose, L.M., Kedenko, L., Rao, M., Struchalin, M., Kleber, M.E., Cavalieri, M., Haun, M., Cornelis, M.C., Ciullo, M., Pirastu, M., De Andrade, M., McEvoy, M.A., Woodward, M., Adam, M., Cocca, M., Nauck, M., Imboden, M., Waldenberger, M., Pruijm, M., Metzger, M., Stumvoll, M., Evans, M.K., Sale, M.M., Kähönen, M., Boban, M., Bochud, M., Rheinberger, M., Verweij, N., Bouatia-Naji, N., Martin, N.G., Hastie, N., Probst-Hensch, N., Soranzo, N., Devuyst, O., Raitakari, O., Gottesman, O., Franco, O.H., Polasek, O., Gasparini, P., Munroe, P.B., Ridker, P.M., Mitchell, P., Muntner, P., Meisinger, C., Smit, J.H., Abecasis, G.R., Adair, L.S., Alexander, M., Altshuler, D., Amin, N., Arking, D.E., Arora, P., Aulchenko, Y., Bakker, S.J.L., Bandinelli, S., Barroso, I., Beckmann, J.S., Beilby, J.P., Bergman, R.N., Bergmann, S., Bis, J.C., Boehnke, M., Bonnycastle, L.L., Bornstein, S.R., Bots, M.L., Bragg-Gresham, J.L., Brand, S.-M., Brand, E., Braund, P.S., Brown, M.J., Burton, P.R., Casas, J.P., Caulfield, M.J., Chakravarti, A., Chambers, J.C., Chandak, G.R., Chang, Y.-P.C., Charchar, F.J., Chaturvedi, N., Cho, Y.S., Clarke, R., Collins, F.S., Collins, R., Connell, J.M., Cooper, J.A., Cooper, M.N., Cooper, R.S., Corsi, A.M., Dörr, M., Dahgam, S., Danesh, J., Smith, G.D., Day, I.N.M., Deloukas, P., Denniff, M., Dominiczak, A.F., Dong, Y., Doumatey, A., Elliott, P., Elosua, R., Erdmann, J., Eyheramendy, S., Farrall, M., Fava, C., Forrester, T., Fowkes, F.G.R., Fox, E.R., Frayling, T.M., Galan, P., Ganesh, S.K., Garcia, M., Gaunt, T.R., Glazer, N.L., Go, M.J., Goel, A., Grässler, J., Grobbee, D.E., Groop, L., Guarrera, S., Guo, X., Hadley, D., Hamsten, A., Han, B.-G., Hardy, R., Hartikainen, A.-L., Heath, S., Heckbert, S.R., Hedblad, B., Hercberg, S., Hernandez, D., Hicks, A.A., Hilton, G., Hingorani, A.D., Hoffman Bolton, J.A., Hopewell, J.C., Howard, P., Humphries, S.E., Hunt, S.C., Hveem, K., Ikram, M.A., Islam, M., Iwai, N., Jarvelin, M.-R., Jackson, A.U., Jafar, T.H., Janipalli, C.S., Johnson, T., Kathiresan, S., Khaw, K.-T., Kim, H.-L., Kinra, S., Kita, Y., Kivimaki, M., Kooner, J.S., Kumar, M.J.K., Kuh, D., Kulkarni, S.R., Kumari, M., Kuusisto, J., Kuznetsova, T., Laakso, M., Laan, M., Laitinen, J., Lakatta, E.G., Langefeld, C.D., Larson, M.G., Lathrop, M., Lawlor, D.A., Lawrence, R.W., Lee, J.-Y., Lee, N.R., Levy, D., Longstreth, W.T., Luan, J., Lucas, G., Ludwig, B., Mangino, M., Mani, K.R., Marmot, M.G., Mattace-Raso, F.U.S., Matullo, G., McArdle, W.L., McKenzie, C.A., Meitinger, T., Melander, O., Meneton, P., Meschia, J.F., Miki, T., Milaneschi, Y., Mohlke, K.L., Mooser, V., Morken, M.A., Morris, R.W., Mosley, T.H., Najjar, S., Narisu, N., Newton-Cheh, C., Nguyen, K.-D.H., Nilsson, P., Nyberg, F., O'Donnell, C.J., Ogihara, T., Ohkubo, T., Okamura, T., Ong, R.T.-H., Ongen, H., Onland-Moret, N.C., O'Reilly, P.F., Org, E., Orru, M., Palmas, W., Palmen, J., Palmer, L.J., Palmer, N.D., Parker, A.N., Peden, J.F., Peltonen, L., Perola, M., Pihur, V., Platou, C.G.P., Plump, A., Prabhakaran, D., Psaty, B.M., Raffel, L.J., Rao, D.C., Rasheed, A., Ricceri, F., Rice, K.M., Rosengren, A., Rotter, J.I., Rudock, M.E., Sõber, S., Salako, T., Saleheen, D., Salomaa, V., Samani, N.J., Schwartz, S.M., Schwarz, P.E.H., Scott, L.J., Scott, J., Scuteri, A., Sehmi, J.S., Seielstad, M., Seshadri, S., Sharma, P., Shaw-Hawkins, S., Shi, G., Shrine, N.R.G., Sijbrands, E.J.G., Sim, X., Singleton, A., Sjögren, M., Smith, N.L., Artigas, M.S., Spector, T.D., Staessen, J.A., Stancakova, A., Steinle, N.I., Strachan, D.P., Stringham, H.M., Sun, Y.V., Swift, A.J., Tabara, Y., Tai, E.-S., Talmud, P.J., Taylor, A., Terzic, J., Thelle, D.S., Tobin, M.D., Tomaszewski, M., Tripathy, V., Tuomilehto, J., Tzoulaki, I., Uda, M., Ueshima, H., Uiterwaal, C.S.P.M., Umemura, S., Van Der Harst, P., Van Der Schouw, Y.T., Van Gilst, W.H., Vartiainen, E., Vasan, R.S., Veldre, G., Verwoert, G.C., Viigimaa, M., Vinay, D.G., Vineis, P., Voight, B.F., Vollenweider, P., Wagenknecht, L.E., Wain, L.V., Wang, X., Wang, T.J., Wareham, N.J., Watkins, H., Weder, A.B., Whincup, P.H., Wiggins, K.L., Witteman, J.C.M., Wong, A., Wu, Y., Yajnik, C.S., Yao, J., Young, J.H., Zelenika, D., Zhai, G., Zhang, W., Zhang, F., Zhao, J.H., Zhu, H., Zhu, X., Zitting, P., Zukowska-Szczechowska, E., Okada, Y., Wu, J.-Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S.-C., Wong, T.-Y., Liu, J., Young, T.L., Aung, T., Teo, Y.-Y., Kim, Y.J., Kang, D., Chen, C.-H., Tsai, F.-J., Chang, L.-C., Fann, S.-J.C., Mei, H., Hixson, J.E., Chen, S., Katsuya, T., Isono, M., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y.-T., Tanaka, T., Reilly, M.P., Schunkert, H., Assimes, T.L., Hall, A., Hengstenberg, C., König, I.R., Laaksonen, R., McPherson, R., Thompson, J.R., Thorsteinsdottir, U., Ziegler, A., Absher, D., Chen, L., Cupples, L.A., Halperin, E., Musunuru, K., Preuss, M., Schillert, A., Thorleifsson, G., Wells, G.A., Holm, H., Roberts, R., Stewart, A.F.R., Fortmann, S., Go, A., Hlatky, M., Iribarren, C., Knowles, J., Myers, R., Quertermous, T., Sidney, S., Risch, N., Tang, H., Blankenberg, S., Schnabel, R., Sinning, C., Lackner, K.J., Tiret, L., Nicaud, V., Cambien, F., Bickel, C., Rupprecht, H.J., Perret, C., Proust, C., Münzel, T.F., Barbalic, M., Chen, I.Y.-D., Demissie-Banjaw, S., Folsom, A., Lumley, T., Marciante, K., Taylor, K.D., Volcik, K., Gretarsdottir, S., Gulcher, J.R., Kong, A., Stefansson, K., Thorgeirsson, G., Andersen, K., Fischer, M., Grosshennig, A., Linsel-Nitschke, P., Stark, K., Schreiber, S., Aherrahrou, Z., Bruse, P., Doering, A., Klopp, N., Diemert, P., Loley, C., Medack, A., Nahrstedt, J., Peters, A., Wagner, A.K., Willenborg, C., Böhm, B.O., Dobnig, H., Grammer, T.B., Hoffmann, M.M., Meinitzer, A., Winkelmann, B.R., Pilz, S., Renner, W., Scharnagl, H., Stojakovic, T., Tomaschitz, A., Winkler, K., Guiducci, C., Burtt, N., Gabriel, S.B., Dandona, S., Jarinova, O., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H.H., Devaney, J., Burnett, M.S., Pichard, A.D., Kent, K.M., Satler, L., Lindsay, J.M., Waksman, R., Knouff, C.W., Waterworth, D.M., Walker, M.C., Epstein, S.E., Rader, D.J., Nelson, C.P., Wright, B.J., Balmforth, A.J., Ball, S.G., Loehr, L.R., Rosamond, W.D., Benjamin, E., Haritunians, T., Couper, D., Murabito, J., Wang, Y.A., Stricker, B.H., Chang, P.P., Willerson, J.T., Felix, S.B., Watzinger, N., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R.J., Greiser, K.H., Deckers, J.W., Stritzke, J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M.M., Werdan, K., Mitchell, G.F., Arnett, D.K., Gottdiener, J.S., Blettner, M., Friedrich, N., Kovacs, P., Wild, P.S., Froguel, P., Rettig, R., Mägi, R., Biffar, R., Schmidt, R., Middelberg, R.P.S., Carroll, R.J., Penninx, B.W., Scott, R.J., Katz, R., Sedaghat, S., Wild, S.H., Kardia, S.L.R., Ulivi, S., Hwang, S.-J., Enroth, S., Kloiber, S., Trompet, S., Stengel, B., Hancock, S.J., Turner, S.T., Rosas, S.E., Stracke, S., Harris, T.B., Zeller, T., Zemunik, T., Lehtimäki, T., Illig, T., Aspelund, T., Nikopensius, T., Esko, T., Gyllensten, U., Völker, U., Emilsson, V., Vitart, V., Aalto, V., Gudnason, V., Chouraki, V., Chen, W.-M., Igl, W., März, W., Koenig, W., Lieb, W., Loos, R.J.F., Liu, Y., Snieder, H., Pramstaller, P.P., Parsa, A., O'Connell, J.R., Susztak, K., Hamet, P., Tremblay, J., De Boer, I.H., Böger, C.A., Goessling, W., Chasman, D.I., Köttgen, A., Kao, W.H.L., and Fox, C.S.
Abstract: Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combining data across 133,413 individuals with replication in up to 42,166 individuals. We identify 24 new and confirm 29 previously identified loci. Of these 53 loci, 19 associate with eGFR among individuals with diabetes. Using bioinformatics, we show that identified genes at eGFR loci are enriched for expression in kidney tissues and in pathways relevant for kidney development and transmembrane transporter activity, kidney structure, and regulation of glucose metabolism. Chromatin state mapping and DNase I hypersensitivity analyses across adult tissues demonstrate preferential mapping of associated variants to regulatory regions in kidney but not extra-renal tissues. These findings suggest that genetic determinants of eGFR are mediated largely through direct effects within the kidney and highlight important cell types and biological pathways. © 2016, Nature Publishing Group. All rights reserved.
Published: 2016

7. Pleiotropic genes for metabolic syndrome and inflammation

Author: Kraja, A. (Aldi), Chasman, D.I. (Daniel), North, K.E. (Kari), Reiner, A. (Alexander), Yanek, L.R. (Lisa), Kilpeläinen, T.O. (Tuomas), Smith, J.A. (Jennifer), Dehghan, A. (Abbas), Dupuis, J. (Josée), Johnson, A.D. (Andrew), Feitosa, M.F. (Mary Furlan), Tekola-Ayele, F. (Fasil), Chu, A.Y. (Audrey), Nolte, I.M. (Ilja), Dastani, Z. (Zari), Morris, A.P. (Andrew), Pendergrass, S.A. (Sarah), Sun, Y.V. (Yan), Ritchie, M.D. (Marylyn), Vaez, A. (Ahmad), Lin, H. (Honghuang), Ligthart, S. (Symen), Marullo, L. (Letizia), Rohde, R. (Rebecca), Shao, Y. (Yaming), Ziegler, M.A. (Mark), Im, K.M. (Kate), Schnabel, R.B. (Renate), Jorgensen, T. (Torben), Jørgensen, M.E. (Marit), Hansen, T. (T.), Pedersen, O. (Oluf), Stolk, R.P. (Ronald), Snieder, H. (Harold), Hofman, A. (Albert), Uitterlinden, A.G. (André), Franco, O.H. (Oscar), Ikram, M.A. (Arfan), Richards, J.B. (Brent), Rotimi, C. (Charles), Wilson, J.G. (James), Lange, L.A. (Leslie), Ganesh, S.K. (Santhi), Nalls, M.A. (Michael), Rasmussen-Torvik, L.J. (Laura), Pankow, J.S. (James), Coresh, J. (Josef), Tang, W. (Weihong), Kao, W.-H.L. (Linda), Boerwinkle, E.A. (Eric), Morrison, A.C. (Alanna), Ridker, P.M. (Paul), Becker, D.M. (Diane), Rotter, J.I. (Jerome), Kardia, S.L.R. (Sharon), Loos, R.J.F. (Ruth), Larson, M.G. (Martin), Hsu, Y.-H. (Yi-Hsiang), Province, M.A. (Mike), Tracy, R.P. (Russell), Voight, B.F. (Benjamin), Vaidya, D. (Dhananjay), O'Donnell, C.J. (Christopher), Benjamin, E.J. (Emelia), Alizadeh, B.Z. (Behrooz), Prokopenko, I. (Inga), Meigs, J.B. (James), Borecki, I.B. (Ingrid), Kraja, A. (Aldi), Chasman, D.I. (Daniel), North, K.E. (Kari), Reiner, A. (Alexander), Yanek, L.R. (Lisa), Kilpeläinen, T.O. (Tuomas), Smith, J.A. (Jennifer), Dehghan, A. (Abbas), Dupuis, J. (Josée), Johnson, A.D. (Andrew), Feitosa, M.F. (Mary Furlan), Tekola-Ayele, F. (Fasil), Chu, A.Y. (Audrey), Nolte, I.M. (Ilja), Dastani, Z. (Zari), Morris, A.P. (Andrew), Pendergrass, S.A. (Sarah), Sun, Y.V. (Yan), Ritchie, M.D. (Marylyn), Vaez, A. (Ahmad), Lin, H. (Honghuang), Ligthart, S. (Symen), Marullo, L. (Letizia), Rohde, R. (Rebecca), Shao, Y. (Yaming), Ziegler, M.A. (Mark), Im, K.M. (Kate), Schnabel, R.B. (Renate), Jorgensen, T. (Torben), Jørgensen, M.E. (Marit), Hansen, T. (T.), Pedersen, O. (Oluf), Stolk, R.P. (Ronald), Snieder, H. (Harold), Hofman, A. (Albert), Uitterlinden, A.G. (André), Franco, O.H. (Oscar), Ikram, M.A. (Arfan), Richards, J.B. (Brent), Rotimi, C. (Charles), Wilson, J.G. (James), Lange, L.A. (Leslie), Ganesh, S.K. (Santhi), Nalls, M.A. (Michael), Rasmussen-Torvik, L.J. (Laura), Pankow, J.S. (James), Coresh, J. (Josef), Tang, W. (Weihong), Kao, W.-H.L. (Linda), Boerwinkle, E.A. (Eric), Morrison, A.C. (Alanna), Ridker, P.M. (Paul), Becker, D.M. (Diane), Rotter, J.I. (Jerome), Kardia, S.L.R. (Sharon), Loos, R.J.F. (Ruth), Larson, M.G. (Martin), Hsu, Y.-H. (Yi-Hsiang), Province, M.A. (Mike), Tracy, R.P. (Russell), Voight, B.F. (Benjamin), Vaidya, D. (Dhananjay), O'Donnell, C.J. (Christopher), Benjamin, E.J. (Emelia), Alizadeh, B.Z. (Behrooz), Prokopenko, I. (Inga), Meigs, J.B. (James), and Borecki, I.B. (Ingrid)
Abstract: Metabolic syndrome (MetS) has become a health and financial burden worldwide. The MetS definition captures clustering of risk factors that predict higher risk for diabetes mellitus and cardiovascular disease. Our study hypothesis is that additional to genes influencing individual MetS risk factors, genetic variants exist that influence MetS and inflammatory markers forming a predisposing MetS genetic network. To test this hypothesis a staged approach was undertaken. (a) We analyzed 17 metabolic and inflammatory traits in more than 85,500 participants from 14 large epidemiological studies within the Cross Consortia Pleiotropy Group. Individuals classified with MetS (NCEP definition), versus those without, showed on average significantly different levels for most inflammatory markers studied. (b) Paired average correlations between 8 metabolic traits and 9 inflammatory markers from the same studies as above, estimated with two methods, and factor analyses on large simulated data, helped in identifying 8 combinations of traits for follow-up
Published: 2014
Full Text: View/download PDF

8. A genome-wide association study of depressive symptoms

Author: Hek, K. (Karin), Demirkan, A. (Ayşe), Lahti, J. (Jari), Terracciano, A., Teumer, A. (Alexander), Cornelis, M. (Marilyn), Amin, N. (Najaf), Bakshis, E. (Erin), Baumert, J. (Jens), Ding, J. (Jingzhong), Liu, Y. (YongMei), Marciante, K. (Kristin), Meirelles, O., Nalls, M.A. (Michael), Sun, Y.V. (Yan), Vogelzangs, N. (Nicole), Yu, L. (Lei), Bandinelli, S. (Stefania), Benjamin, E.J. (Emelia), Bennett, D.A. (David), Boomsma, D.I. (Dorret), Cannas, A., Coker, L.H. (Laura), Geus, E.J.C. (Eco) de, Jager, P.L. (Philip) de, Diez Roux, A.V. (Ana), Purcell, S. (Shaun), Hu, F.B. (Frank), Rimm, E., Hunter, D.J. (David), Jensen, M.K. (Majken), Curhan, G.C. (Gary), Rice, K.M. (Kenneth), Penman, A.D. (Alan), Rotter, J.I. (Jerome), Sotoodehnia, N. (Nona), Emeny, R. (Rebecca), Eriksson, J.G. (Johan), Evans, D.A. (Denis), Ferrucci, L. (Luigi), Fornage, M. (Myriam), Gudnason, V. (Vilmundur), Hofman, A. (Albert), Illig, T. (Thomas), Kardia, S.L.R. (Sharon), Kelly-Hayes, M. (Margaret), Koenen, M.E. (Marjorie), Kraft, P. (Peter), Kuningas, M. (Maris), Massaro, J. (Joseph), Melzer, D. (David), Mulas, A. (Antonella), Mulder, C.L. (Niels), Murray, A. (Anna), Oostra, B.A. (Ben), Palotie, A. (Aarno), Penninx, B.W.J.H. (Brenda), Petersmann, A. (Astrid), Pilling, L.C. (Luke), Psaty, B.M. (Bruce), Rawal, R. (Rajesh), Reiman, E.M. (Eric), Schulz, A. (Ansgar), Shulman, L. (Lee), Singleton, A.B. (Andrew), Smith, A.V. (Davey), Sutin, A.R., Uitterlinden, A.G. (André), Völzke, H. (Henry), Widen, E. (Elisabeth), Yaffe, K. (Kristine), Zonderman, A.B. (Alan), Cucca, F. (Francesco), Harris, T.B. (Tamara), Ladwig, K.-H. (Karl-Heinz), Llewellyn, D.J. (David), Räikkönen, K. (Katri), Tanaka, T. (Toshiko), Duijn, C.M. (Cornelia) van, Grabe, H.J. (Hans Jörgen), Launer, L.J. (Lenore), Lunetta, K.L. (Kathryn), Mosley, T.H. (Thomas), Newman, A.B. (Anne), Tiemeier, H.W. (Henning), Murabito, J. (Joanne), Hek, K. (Karin), Demirkan, A. (Ayşe), Lahti, J. (Jari), Terracciano, A., Teumer, A. (Alexander), Cornelis, M. (Marilyn), Amin, N. (Najaf), Bakshis, E. (Erin), Baumert, J. (Jens), Ding, J. (Jingzhong), Liu, Y. (YongMei), Marciante, K. (Kristin), Meirelles, O., Nalls, M.A. (Michael), Sun, Y.V. (Yan), Vogelzangs, N. (Nicole), Yu, L. (Lei), Bandinelli, S. (Stefania), Benjamin, E.J. (Emelia), Bennett, D.A. (David), Boomsma, D.I. (Dorret), Cannas, A., Coker, L.H. (Laura), Geus, E.J.C. (Eco) de, Jager, P.L. (Philip) de, Diez Roux, A.V. (Ana), Purcell, S. (Shaun), Hu, F.B. (Frank), Rimm, E., Hunter, D.J. (David), Jensen, M.K. (Majken), Curhan, G.C. (Gary), Rice, K.M. (Kenneth), Penman, A.D. (Alan), Rotter, J.I. (Jerome), Sotoodehnia, N. (Nona), Emeny, R. (Rebecca), Eriksson, J.G. (Johan), Evans, D.A. (Denis), Ferrucci, L. (Luigi), Fornage, M. (Myriam), Gudnason, V. (Vilmundur), Hofman, A. (Albert), Illig, T. (Thomas), Kardia, S.L.R. (Sharon), Kelly-Hayes, M. (Margaret), Koenen, M.E. (Marjorie), Kraft, P. (Peter), Kuningas, M. (Maris), Massaro, J. (Joseph), Melzer, D. (David), Mulas, A. (Antonella), Mulder, C.L. (Niels), Murray, A. (Anna), Oostra, B.A. (Ben), Palotie, A. (Aarno), Penninx, B.W.J.H. (Brenda), Petersmann, A. (Astrid), Pilling, L.C. (Luke), Psaty, B.M. (Bruce), Rawal, R. (Rajesh), Reiman, E.M. (Eric), Schulz, A. (Ansgar), Shulman, L. (Lee), Singleton, A.B. (Andrew), Smith, A.V. (Davey), Sutin, A.R., Uitterlinden, A.G. (André), Völzke, H. (Henry), Widen, E. (Elisabeth), Yaffe, K. (Kristine), Zonderman, A.B. (Alan), Cucca, F. (Francesco), Harris, T.B. (Tamara), Ladwig, K.-H. (Karl-Heinz), Llewellyn, D.J. (David), Räikkönen, K. (Katri), Tanaka, T. (Toshiko), Duijn, C.M. (Cornelia) van, Grabe, H.J. (Hans Jörgen), Launer, L.J. (Lenore), Lunetta, K.L. (Kathryn), Mosley, T.H. (Thomas), Newman, A.B. (Anne), Tiemeier, H.W. (Henning), and Murabito, J. (Joanne)
Abstract: Background: Depression is a heritable trait that exists on a continuum of varying severity and duration. Yet, the search for genetic variants associated with depression has had few successes. We exploit the entire continuum of depression to find common variants for depressive symptoms. Methods: In this genome-wide association study, we combined the results of 17 population-based studies assessing depressive symptoms with the Center for Epidemiological Studies Depression Scale. Replication of the independent top hits (p<1×10-5) was performed in five studies assessing depressive symptoms with other instruments. In addition, we performed a combined meta-analysis of all 22 discovery and replication studies. Results: The discovery sample comprised 34,549 individuals (mean age of 66.5) and no loci reached genome-wide significance (lowest p = 1.05×10-7). Seven independent single nucleotide polymorphisms were considered for replication. In the replication set (n = 16,709), we found suggestive association of one single nucleotide polymorphism with depressive symptoms (rs161645, 5q21, p = 9.19×10-3). This 5q21 region reached genome-wide significance (p = 4.78×10-8) in the overall meta-analysis combining discovery and replication studies (n = 51,258). Conclusions: The results suggest that only a large sample comprising more than 50,000 subjects may be sufficiently powered to detect genes for depressive symptoms.
Published: 2013
Full Text: View/download PDF

9. Association Between Chromosome 9p21 Variants and the Ankle-Brachial Index Identified by a Meta-Analysis of 21 Genome-Wide Association Studies

Author: Murabito, J.M., White, C.C., Kavousi, M., Sun, Y.V., Feitosa, M.F., Nambi, V., Lamina, C., Schillert, A., Coassin, S., Bis, J.C., Broer, L., Crawford, D.C., Franceschini, N., Frikke-Schmidt, R., Haun, M., Holewijn, S., Huffman, J.E., Hwang, S.J., Kiechl, S., Kollerits, B., Montasser, M.E., Nolte, I.M., Rudock, M.E., Senft, A., Teumer, A., van der Harst, P., Vitart, V., Waite, L.L., Wood, A.R., Wassel, C.L., Absher, D.M., Allison, M.A., Amin, N., Arnold, A., Asselbergs, F.W., Aulchenko, Y., Bandinelli, S., Barbalic, M., Boban, M., Brown-Gentry, K., Couper, D.J., Criqui, M.H., Dehghan, A., den Heijer, M., Dieplinger, B., Ding, J.Z., Dorr, M., Espinola-Klein, C., Felix, S.B., Ferrucci, L., Folsom, A.R., Fraedrich, G., Gibson, Q., Goodloe, R., Gunjaca, G., Haltmayer, M., Heiss, G., Hofman, A., Kieback, A., Kiemeney, L.A., Kolcic, I., Kullo, I.J., Kritchevsky, S.B., Lackner, K.J., Li, X.H., Lieb, W.G., Lohman, K., Meisinger, C., Melzer, D., Mohler, E.R., Mudnic, I., Mueller, T., Navis, G., Oberhollenzer, F., Olin, J.W., O'Connell, J., O'Donnell, C.J., Palmas, W., Penninx, B.W.J.H., Petersmann, A., Polasek, O., Psaty, B.M., Rantner, B., Rice, K., Rivadeneira, F., Rotter, J.I., Seldenrijk, A., Stadler, M., Summerer, M., Tanaka, T., Tybjaerg-Hansen, A., Uitterlinden, A. G., van Gilst, W.H., Vermeulen, S.H., Wild, S.H., Wild, P.S., Willeit, J., Zeller, T., Zemunik, T., Murabito, J.M., White, C.C., Kavousi, M., Sun, Y.V., Feitosa, M.F., Nambi, V., Lamina, C., Schillert, A., Coassin, S., Bis, J.C., Broer, L., Crawford, D.C., Franceschini, N., Frikke-Schmidt, R., Haun, M., Holewijn, S., Huffman, J.E., Hwang, S.J., Kiechl, S., Kollerits, B., Montasser, M.E., Nolte, I.M., Rudock, M.E., Senft, A., Teumer, A., van der Harst, P., Vitart, V., Waite, L.L., Wood, A.R., Wassel, C.L., Absher, D.M., Allison, M.A., Amin, N., Arnold, A., Asselbergs, F.W., Aulchenko, Y., Bandinelli, S., Barbalic, M., Boban, M., Brown-Gentry, K., Couper, D.J., Criqui, M.H., Dehghan, A., den Heijer, M., Dieplinger, B., Ding, J.Z., Dorr, M., Espinola-Klein, C., Felix, S.B., Ferrucci, L., Folsom, A.R., Fraedrich, G., Gibson, Q., Goodloe, R., Gunjaca, G., Haltmayer, M., Heiss, G., Hofman, A., Kieback, A., Kiemeney, L.A., Kolcic, I., Kullo, I.J., Kritchevsky, S.B., Lackner, K.J., Li, X.H., Lieb, W.G., Lohman, K., Meisinger, C., Melzer, D., Mohler, E.R., Mudnic, I., Mueller, T., Navis, G., Oberhollenzer, F., Olin, J.W., O'Connell, J., O'Donnell, C.J., Palmas, W., Penninx, B.W.J.H., Petersmann, A., Polasek, O., Psaty, B.M., Rantner, B., Rice, K., Rivadeneira, F., Rotter, J.I., Seldenrijk, A., Stadler, M., Summerer, M., Tanaka, T., Tybjaerg-Hansen, A., Uitterlinden, A. G., van Gilst, W.H., Vermeulen, S.H., Wild, S.H., Wild, P.S., Willeit, J., Zeller, T., and Zemunik, T.
Abstract: Background-Genetic determinants of peripheral arterial disease (PAD) remain largely unknown. To identify genetic variants associated with the ankle-brachial index (ABI), a noninvasive measure of PAD, we conducted a meta-analysis of genome-wide association study data from 21 population-based cohorts. Methods and Results-Continuous ABI and PAD (ABI <0.9) phenotypes adjusted for age and sex were examined. Each study conducted genotyping and imputed data to the <2.5 million single nucleotide polymorphisms (SNPs) in HapMap. Linear and logistic regression models were used to test each SNP for association with ABI and PAD using additive genetic models. Study-specific data were combined using fixed effects inverse variance weighted meta-analyses. There were a total of 41 692 participants of European ancestry (<60% women, mean ABI 1.02 to 1.19), including 3409 participants with PAD and with genome-wide association study data available. In the discovery meta-analysis, rs10757269 on chromosome 9 near CDKN2B had the strongest association with ABI (β-0.006, P=2.46×10-8). We sought replication of the 6 strongest SNP associations in 5 population-based studies and 3 clinical samples (n=16 717). The association for rs10757269 strengthened in the combined discovery and replication analysis (P=2.65×10-9). No other SNP associations for ABI or PAD achieved genome-wide significance. However, 2 previously reported candidate genes for PAD and 1 SNP associated with coronary artery disease were associated with ABI: DAB21P (rs13290547, P=3.6×10-5), CYBA (rs3794624, P=6.3×10-5), and rs1122608 (LDLR, P=0.0026). Conclusions-Genome-wide association studies in more than 40 000 individuals identified 1 genome wide significant association on chromosome 9p21 with ABI. Two candidate genes for PAD and 1 SNP for coronary artery disease are associated with ABI. © 2012 American Heart Association, Inc.
Published: 2012
Full Text: View/download PDF

10. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

Author: DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Multiple Tissue Human Expression Resource (MUTHER) Consortium, Ahmadi, K.R., Ainali, C., Barrett, A., Bataille, V., Bell, J.T., Buil, A., Deloukas, P., Dermitzakis, E.T., Dimas, A.S., Durbin, R., Glass, D., Grundberg, E., Hassanali, N., Hedman, Å.K., Ingle, C., Knowles, D., Krestyaninova, M., Lindgren, C.M., Lowe, C.E., McCarthy, M.I., Meduri, E., di Meglio, P., Min, J.L., Montgomery, S.B., Nestle, F.O., Nica, A.C., Nisbet, J., O'Rahilly, S., Parts, L., Potter, S., Sekowska, M., Shin, S.Y., Small, K.S., Soranzo, N., Spector, T.D., Surdulescu, G., Travers, M.E., Tsaprouni, L., Tsoka, S., Wilk, A., Yang, T.P., Zondervan, K.T., Voight, B.F., Scott, L.J., Steinthorsdottir, V., Morris, A.P., Dina, C., Welch, R.P., Zeggini, E., Huth, C., Aulchenko, Y.S., Thorleifsson, G., McCulloch, L.J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C.J., Raychaudhuri, S., McCarroll, S.A., Langenberg, C., Hofmann, O.M., Dupuis, J., Qi, L., Segrè, A.V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A.J., Blagieva, R., Boerwinkle, E., Bonnycastle, L.L., Boström, K.B., Bravenboer, B., Bumpstead, S., Burtt, N.P., Charpentier, G., Chines, P.S., Cornelis, M., Couper, D.J., Crawford, G., Doney, A.S., Elliott, K.S., Elliott, A.L., Erdos, M.R., Fox, C.S., Franklin, C.S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C.J., Guiducci, C., Hadjadj, S., Herder, C., Isomaa, B., Jackson, A.U., Johnson, P.R., Jørgensen, T., Kao, W.H., Klopp, N., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M.A., Narisu, N., Nilsson, P., Owen, K.R., Payne, F., Perry, J.R., Petersen, A.K., Platou, C., Proença, C., Prokopenko, I., Rathmann, W., Rayner, N.W., Robertson, N.R., Rocheleau, G., Roden, M., Sampson, M.J., Saxena, R., Shields, B.M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Stringham, H.M., Sun, Q., Swift, A.J., Thorand, B., Tichet, J., Tuomi, T., van Dam, R.M., van Haeften, T.W., van Herpt, T., van Vliet-Ostaptchouk, J.V., Walters, G.B., Weedon, M.N., Wijmenga, C., Witteman, J., Bergman, R.N., Cauchi, S., Collins, F.S., Gloyn, A.L., Gyllensten, U., Hansen, T., Hide, W.A., Hitman, G.A., Hofman, A., Hunter, D.J., Hveem, K., Laakso, M., Mohlke, K.L., Morris, A.D., Palmer, C.N., Pramstaller, P.P., Rudan, I., Sijbrands, E., Stein, L.D., Tuomilehto, J., Uitterlinden, A., Walker, M., Wareham, N.J., Watanabe, R.M., Abecasis, G.R., Boehm, B.O., Campbell, H., Daly, M.J., Hattersley, A.T., Hu, F.B., Meigs, J.B., Pankow, J.S., Pedersen, O., Wichmann, H.E., Barroso, I., Florez, J.C., Frayling, T.M., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J.F., Illig, T., Froguel, P., van Duijn, C.M., Stefansson, K., Altshuler, D., Boehnke, M., Manning, A.K., Hivert, M.F., Scott, R.A., Grimsby, J.L., Bouatia-Naji, N., Chen, H., Rybin, D., Liu, C.T., Bielak, L.F., Barnes, D., Cadby, G., Hottenga, J.J., Ingelsson, E., Johnson, T., Kanoni, S., Ladenvall, C., Lagou, V., Lahti, J., Lecoeur, C., Liu, Y., Martinez-Larrad, M.T., Montasser, M.E., Rasmussen-Torvik, L.J., Salo, P., Sattar, N., Shungin, D., Strawbridge, R.J., Tanaka, T., An, P., de Andrade, M., Andrews, J.S., Aspelund, T., Atalay, M., Aulchenko, Y., Bandinelli, S., Beckmann, J.S., Beilby, J.P., Bellis, C., Blangero, J., Boban, M., Boomsma, D.I., Borecki, I.B., Böttcher, Y., Bouchard, C., Brunner, E., Budimir, D., Carlson, O., Clarke, R., Corbatón-Anchuelo, A., Couper, D., de Faire, U., Dedoussis, G.V., Dimitriou, M., Egan, J.M., Eiriksdottir, G., Eriksson, J.G., Eury, E., Ferrucci, L., Ford, I., Forouhi, N.G., Franzosi, M.G., Franks, P.W., Galan, P., de Geus, E., Gigante, B., Glazer, N.L., Goel, A., Gudnason, V., Hallmans, G., Hamsten, A., Hansson, O., Harris, T.B., Hayward, C., Heath, S., Hercberg, S., Hicks, A.A., Hingorani, A., Hui, J., Hung, J., Jarvelin, M.R., Jhun, M.A., Johnson, P.C., Jukema, J.W., Jula, A., Kaprio, J., Kardia, S.L., Keinanen-Kiukaanniemi, S., Kivimaki, M., Kolcic, I., Kovacs, P., Kumari, M., Kyvik, K.O., Lakka, T., Lannfelt, L., Lathrop, G.M., Launer, L.J., Leander, K., Li, G., Lind, L., Lindstrom, J., Lobbens, S., Loos, R.J., Luan, J., Mägi, R., Magnusson, P.K., Marmot, M., Meneton, P., Mooser, V., Miljkovic, I., O'Connell, J., Ong, K.K., Oostra, B.A., Palmer, L.J., Palotie, A., Peden, J.F., Pedersen, N.L., Pehlic, M., Peltonen, L., Penninx, B., Pericic, M., Perola, M., Perusse, L., Peyser, P.A., Polasek, O., Province, M.A., Räikkönen, K., Rauramaa, R., Rehnberg, E., Rice, K., Rotter, J.I., Ruokonen, A., Saaristo, T., Sabater-Lleal, M., Salomaa, V., Savage, D.B., Schwarz, P., Seedorf, U., Sennblad, B., Serrano-Rios, M., Shuldiner, A.R., Sijbrands, E.J., Siscovick, D.S., Smit, J.H., Smith, N.L., Smith, A.V., Stančáková, A., Stirrups, K., Stumvoll, M., Sun, Y.V., Tönjes, A., Trompet, S., Uitterlinden, A.G., Uusitupa, M., Vikström, M., Vitart, V., Vohl, M.C., Vollenweider, P., Waeber, G., Waterworth, D.M., Watkins, H., Wheeler, E., Widen, E., Wild, S.H., Willems, S.M., Willemsen, G., Witteman, J.C., Wright, A.F., Yaghootkar, H., Zelenika, D., Zemunik, T., Zgaga, L., DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Multiple Tissue Human Expression Resource (MUTHER) Consortium, Ahmadi, K.R., Ainali, C., Barrett, A., Bataille, V., Bell, J.T., Buil, A., Deloukas, P., Dermitzakis, E.T., Dimas, A.S., Durbin, R., Glass, D., Grundberg, E., Hassanali, N., Hedman, Å.K., Ingle, C., Knowles, D., Krestyaninova, M., Lindgren, C.M., Lowe, C.E., McCarthy, M.I., Meduri, E., di Meglio, P., Min, J.L., Montgomery, S.B., Nestle, F.O., Nica, A.C., Nisbet, J., O'Rahilly, S., Parts, L., Potter, S., Sekowska, M., Shin, S.Y., Small, K.S., Soranzo, N., Spector, T.D., Surdulescu, G., Travers, M.E., Tsaprouni, L., Tsoka, S., Wilk, A., Yang, T.P., Zondervan, K.T., Voight, B.F., Scott, L.J., Steinthorsdottir, V., Morris, A.P., Dina, C., Welch, R.P., Zeggini, E., Huth, C., Aulchenko, Y.S., Thorleifsson, G., McCulloch, L.J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C.J., Raychaudhuri, S., McCarroll, S.A., Langenberg, C., Hofmann, O.M., Dupuis, J., Qi, L., Segrè, A.V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A.J., Blagieva, R., Boerwinkle, E., Bonnycastle, L.L., Boström, K.B., Bravenboer, B., Bumpstead, S., Burtt, N.P., Charpentier, G., Chines, P.S., Cornelis, M., Couper, D.J., Crawford, G., Doney, A.S., Elliott, K.S., Elliott, A.L., Erdos, M.R., Fox, C.S., Franklin, C.S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C.J., Guiducci, C., Hadjadj, S., Herder, C., Isomaa, B., Jackson, A.U., Johnson, P.R., Jørgensen, T., Kao, W.H., Klopp, N., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M.A., Narisu, N., Nilsson, P., Owen, K.R., Payne, F., Perry, J.R., Petersen, A.K., Platou, C., Proença, C., Prokopenko, I., Rathmann, W., Rayner, N.W., Robertson, N.R., Rocheleau, G., Roden, M., Sampson, M.J., Saxena, R., Shields, B.M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Stringham, H.M., Sun, Q., Swift, A.J., Thorand, B., Tichet, J., Tuomi, T., van Dam, R.M., van Haeften, T.W., van Herpt, T., van Vliet-Ostaptchouk, J.V., Walters, G.B., Weedon, M.N., Wijmenga, C., Witteman, J., Bergman, R.N., Cauchi, S., Collins, F.S., Gloyn, A.L., Gyllensten, U., Hansen, T., Hide, W.A., Hitman, G.A., Hofman, A., Hunter, D.J., Hveem, K., Laakso, M., Mohlke, K.L., Morris, A.D., Palmer, C.N., Pramstaller, P.P., Rudan, I., Sijbrands, E., Stein, L.D., Tuomilehto, J., Uitterlinden, A., Walker, M., Wareham, N.J., Watanabe, R.M., Abecasis, G.R., Boehm, B.O., Campbell, H., Daly, M.J., Hattersley, A.T., Hu, F.B., Meigs, J.B., Pankow, J.S., Pedersen, O., Wichmann, H.E., Barroso, I., Florez, J.C., Frayling, T.M., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J.F., Illig, T., Froguel, P., van Duijn, C.M., Stefansson, K., Altshuler, D., Boehnke, M., Manning, A.K., Hivert, M.F., Scott, R.A., Grimsby, J.L., Bouatia-Naji, N., Chen, H., Rybin, D., Liu, C.T., Bielak, L.F., Barnes, D., Cadby, G., Hottenga, J.J., Ingelsson, E., Johnson, T., Kanoni, S., Ladenvall, C., Lagou, V., Lahti, J., Lecoeur, C., Liu, Y., Martinez-Larrad, M.T., Montasser, M.E., Rasmussen-Torvik, L.J., Salo, P., Sattar, N., Shungin, D., Strawbridge, R.J., Tanaka, T., An, P., de Andrade, M., Andrews, J.S., Aspelund, T., Atalay, M., Aulchenko, Y., Bandinelli, S., Beckmann, J.S., Beilby, J.P., Bellis, C., Blangero, J., Boban, M., Boomsma, D.I., Borecki, I.B., Böttcher, Y., Bouchard, C., Brunner, E., Budimir, D., Carlson, O., Clarke, R., Corbatón-Anchuelo, A., Couper, D., de Faire, U., Dedoussis, G.V., Dimitriou, M., Egan, J.M., Eiriksdottir, G., Eriksson, J.G., Eury, E., Ferrucci, L., Ford, I., Forouhi, N.G., Franzosi, M.G., Franks, P.W., Galan, P., de Geus, E., Gigante, B., Glazer, N.L., Goel, A., Gudnason, V., Hallmans, G., Hamsten, A., Hansson, O., Harris, T.B., Hayward, C., Heath, S., Hercberg, S., Hicks, A.A., Hingorani, A., Hui, J., Hung, J., Jarvelin, M.R., Jhun, M.A., Johnson, P.C., Jukema, J.W., Jula, A., Kaprio, J., Kardia, S.L., Keinanen-Kiukaanniemi, S., Kivimaki, M., Kolcic, I., Kovacs, P., Kumari, M., Kyvik, K.O., Lakka, T., Lannfelt, L., Lathrop, G.M., Launer, L.J., Leander, K., Li, G., Lind, L., Lindstrom, J., Lobbens, S., Loos, R.J., Luan, J., Mägi, R., Magnusson, P.K., Marmot, M., Meneton, P., Mooser, V., Miljkovic, I., O'Connell, J., Ong, K.K., Oostra, B.A., Palmer, L.J., Palotie, A., Peden, J.F., Pedersen, N.L., Pehlic, M., Peltonen, L., Penninx, B., Pericic, M., Perola, M., Perusse, L., Peyser, P.A., Polasek, O., Province, M.A., Räikkönen, K., Rauramaa, R., Rehnberg, E., Rice, K., Rotter, J.I., Ruokonen, A., Saaristo, T., Sabater-Lleal, M., Salomaa, V., Savage, D.B., Schwarz, P., Seedorf, U., Sennblad, B., Serrano-Rios, M., Shuldiner, A.R., Sijbrands, E.J., Siscovick, D.S., Smit, J.H., Smith, N.L., Smith, A.V., Stančáková, A., Stirrups, K., Stumvoll, M., Sun, Y.V., Tönjes, A., Trompet, S., Uitterlinden, A.G., Uusitupa, M., Vikström, M., Vitart, V., Vohl, M.C., Vollenweider, P., Waeber, G., Waterworth, D.M., Watkins, H., Wheeler, E., Widen, E., Wild, S.H., Willems, S.M., Willemsen, G., Witteman, J.C., Wright, A.F., Yaghootkar, H., Zelenika, D., Zemunik, T., and Zgaga, L.
Abstract: Recent genome-wide association studies have described many loci implicated in type 2 diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the understanding of the genetic basis of insulin resistance. We hypothesized that genes implicated in insulin resistance pathways might be uncovered by accounting for differences in body mass index (BMI) and potential interactions between BMI and genetic variants. We applied a joint meta-analysis approach to test associations with fasting insulin and glucose on a genome-wide scale. We present six previously unknown loci associated with fasting insulin at P < 5 × 10(-8) in combined discovery and follow-up analyses of 52 studies comprising up to 96,496 non-diabetic individuals. Risk variants were associated with higher triglyceride and lower high-density lipoprotein (HDL) cholesterol levels, suggesting a role for these loci in insulin resistance pathways. The discovery of these loci will aid further characterization of the role of insulin resistance in T2D pathophysiology.
Published: 2012

11. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

Author: International Consortium for Blood Pressure Genome-Wide Association Studies, CARDIoGRAM consortium, CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, CHARGE-HF consortium, Ehret, G.B., Munroe, P.B., Rice, K.M., Bochud, M., Johnson, A.D., Chasman, D.I., Smith, A.V., Tobin, M.D., Verwoert, G.C., Hwang, S.J., Pihur, V., Vollenweider, P., O'Reilly, P.F., Amin, N., Bragg-Gresham, J.L., Teumer, A., Glazer, N.L., Launer, L., Zhao, J.H., Aulchenko, Y., Heath, S., Sõber, S., Parsa, A., Luan, J., Arora, P., Dehghan, A., Zhang, F., Lucas, G., Hicks, A.A., Jackson, A.U., Peden, J.F., Tanaka, T., Wild, S.H., Rudan, I., Igl, W., Milaneschi, Y., Parker, A.N., Fava, C., Chambers, J.C., Fox, E.R., Kumari, M., Go, M.J., van der Harst, P., Kao, W.H., Sjögren, M., Vinay, D.G., Alexander, M., Tabara, Y., Shaw-Hawkins, S., Whincup, P.H., Liu, Y., Shi, G., Kuusisto, J., Tayo, B., Seielstad, M., Sim, X., Nguyen, K.D., Lehtimäki, T., Matullo, G., Wu, Y., Gaunt, T.R., Onland-Moret, N.C., Cooper, M.N., Platou, C.G., Org, E., Hardy, R., Dahgam, S., Palmen, J., Vitart, V., Braund, P.S., Kuznetsova, T., Uiterwaal, C.S., Adeyemo, A., Palmas, W., Campbell, H., Ludwig, B., Tomaszewski, M., Tzoulaki, I., Palmer, N.D., Aspelund, T., Garcia, M., Chang, Y.P., O'Connell, J.R., Steinle, N.I., Grobbee, D.E., Arking, D.E., Kardia, S.L., Morrison, A.C., Hernandez, D., Najjar, S., McArdle, W.L., Hadley, D., Brown, M.J., Connell, J.M., Hingorani, A.D., Day, I.N., Lawlor, D.A., Beilby, J.P., Lawrence, R.W., Clarke, R., Hopewell, J.C., Ongen, H., Dreisbach, A.W., Li, Y., Young, J.H., Bis, J.C., Kähönen, M., Viikari, J., Adair, L.S., Lee, N.R., Chen, M.H., Olden, M., Pattaro, C., Bolton, J.A., Köttgen, A., Bergmann, S., Mooser, V., Chaturvedi, N., Frayling, T.M., Islam, M., Jafar, T.H., Erdmann, J., Kulkarni, S.R., Bornstein, S.R., Grässler, J., Groop, L., Voight, B.F., Kettunen, J., Howard, P., Taylor, A., Guarrera, S., Ricceri, F., Emilsson, V., Plump, A., Barroso, I., Khaw, K.T., Weder, A.B., Hunt, S.C., Sun, Y.V., Bergman, R.N., Collins, F.S., Bonnycastle, L.L., Scott, L.J., Stringham, H.M., Peltonen, L., Perola, M., Vartiainen, E., Brand, S.M., Staessen, J.A., Wang, T.J., Burton, P.R., Artigas, M.S., Dong, Y., Snieder, H., Wang, X., Zhu, H., Lohman, K.K., Rudock, M.E., Heckbert, S.R., Smith, N.L., Wiggins, K.L., Doumatey, A., Shriner, D., Veldre, G., Viigimaa, M., Kinra, S., Prabhakaran, D., Tripathy, V., Langefeld, C.D., Rosengren, A., Thelle, D.S., Corsi, A.M., Singleton, A., Forrester, T., Hilton, G., McKenzie, C.A., Salako, T., Iwai, N., Kita, Y., Ogihara, T., Ohkubo, T., Okamura, T., Ueshima, H., Umemura, S., Eyheramendy, S., Meitinger, T., Wichmann, H.E., Cho, Y.S., Kim, H.L., Lee, J.Y., Scott, J., Sehmi, J.S., Zhang, W., Hedblad, B., Nilsson, P., Smith, G.D., Wong, A., Narisu, N., Stančáková, A., Raffel, L.J., Yao, J., Kathiresan, S., O'Donnell, C.J., Schwartz, S.M., Ikram, M.A., Longstreth, W.T., Mosley, T.H., Seshadri, S., Shrine, N.R., Wain, L.V., Morken, M.A., Swift, A.J., Laitinen, J., Prokopenko, I., Zitting, P., Cooper, J.A., Humphries, S.E., Danesh, J., Rasheed, A., Goel, A., Hamsten, A., Watkins, H., Bakker, S.J., van Gilst, W.H., Janipalli, C.S., Mani, K.R., Yajnik, C.S., Hofman, A., Mattace-Raso, F.U., Oostra, B.A., Demirkan, A., Isaacs, A., Rivadeneira, F., Lakatta, E.G., Orru, M., Scuteri, A., Ala-Korpela, M., Kangas, A.J., Lyytikäinen, L.P., Soininen, P., Tukiainen, T., Würtz, P., Ong, R.T., Dörr, M., Kroemer, H.K., Völker, U., Völzke, H., Galan, P., Hercberg, S., Lathrop, M., Zelenika, D., Deloukas, P., Mangino, M., Spector, T.D., Zhai, G., Meschia, J.F., Nalls, M.A., Sharma, P., Terzic, J., Kumar, M.V., Denniff, M., Zukowska-Szczechowska, E., Wagenknecht, L.E., Fowkes, F.G., Charchar, F.J., Schwarz, P.E., Hayward, C., Guo, X., Rotimi, C., Bots, M.L., Brand, E., Samani, N.J., Polasek, O., Talmud, P.J., Nyberg, F., Kuh, D., Laan, M., Hveem, K., Palmer, L.J., van der Schouw, Y.T., Casas, J.P., Mohlke, K.L., Vineis, P., Raitakari, O., Ganesh, S.K., Wong, T.Y., Tai, E.S., Cooper, R.S., Laakso, M., Rao, D.C., Harris, T.B., Morris, R.W., Dominiczak, A.F., Kivimaki, M., Marmot, M.G., Miki, T., Saleheen, D., Chandak, G.R., Coresh, J., Navis, G., Salomaa, V., Han, B.G., Zhu, X., Kooner, J.S., Melander, O., Ridker, P.M., Bandinelli, S., Gyllensten, U.B., Wright, A.F., Wilson, J.F., Ferrucci, L., Farrall, M., Tuomilehto, J., Pramstaller, P.P., Elosua, R., Soranzo, N., Sijbrands, E.J., Altshuler, D., Loos, R.J., Shuldiner, A.R., Gieger, C., Meneton, P., Uitterlinden, A.G., Wareham, N.J., Gudnason, V., Rotter, J.I., Rettig, R., Uda, M., Strachan, D.P., Witteman, J.C., Hartikainen, A.L., Beckmann, J.S., Boerwinkle, E., Vasan, R.S., Boehnke, M., Larson, M.G., Järvelin, M.R., Psaty, B.M., Abecasis, G.R., Chakravarti, A., Elliott, P., van Duijn, C.M., Newton-Cheh, C., Levy, D., Caulfield, M.J., Johnson, T., Tang, H., Knowles, J., Hlatky, M., Fortmann, S., Assimes, T.L., Quertermous, T., Go, A., Iribarren, C., Absher, D., Risch, N., Myers, R., Sidney, S., Ziegler, A., Schillert, A., Bickel, C., Sinning, C., Rupprecht, H.J., Lackner, K., Wild, P., Schnabel, R., Blankenberg, S., Zeller, T., Münzel, T., Perret, C., Cambien, F., Tiret, L., Nicaud, V., Proust, C., Uitterlinden, A., van Duijn, C., Whitteman, J., Cupples, L.A., Demissie-Banjaw, S., Ramachandran, V., Smith, A., Folsom, A., Morrison, A., Chen, I.Y., Bis, J., Volcik, K., Rice, K., Taylor, K.D., Marciante, K., Smith, N., Glazer, N., Heckbert, S., Harris, T., Lumley, T., Kong, A., Thorleifsson, G., Thorgeirsson, G., Holm, H., Gulcher, J.R., Stefansson, K., Andersen, K., Gretarsdottir, S., Thorsteinsdottir, U., Preuss, M., Schreiber, S., König, I.R., Lieb, W., Hengstenberg, C., Schunkert, H., Fischer, M., Grosshennig, A., Medack, A., Stark, K., Linsel-Nitschke, P., Bruse, P., Aherrahrou, Z., Peters, A., Loley, C., Willenborg, C., Nahrstedt, J., Freyer, J., Gulde, S., Doering, A., Meisinger, C., Klopp, N., Illig, T., Meinitzer, A., Tomaschitz, A., Halperin, E., Dobnig, H., Scharnagl, H., Kleber, M., Laaksonen, R., Pilz, S., Grammer, T.B., Stojakovic, T., Renner, W., März, W., Böhm, B.O., Winkelmann, B.R., Winkler, K., Hoffmann, M.M., Siscovick, D.S., Musunuru, K., Barbalic, M., Guiducci, C., Burtt, N., Gabriel, S.B., Stewart, A.F., Wells, G.A., Chen, L., Jarinova, O., Roberts, R., McPherson, R., Dandona, S., Pichard, A.D., Rader, D.J., Devaney, J., Lindsay, J.M., Kent, K.M., Qu, L., Satler, L., Burnett, M.S., Li, M., Reilly, M.P., Wilensky, R., Waksman, R., Epstein, S., Matthai, W., Knouff, C.W., Waterworth, D.M., Hakonarson, H.H., Walker, M.C., Hall, A.S., Balmforth, A.J., Wright, B.J., Nelson, C., Thompson, J.R., Ball, S.G., Felix, J.F., Demissie, S., Loehr, L.R., Rosamond, W.D., Folsom, A.R., Benjamin, E., Aulchenko, Y.S., Haritunians, T., Couper, D., Murabito, J., Wang, Y.A., Stricker, B.H., Gottdiener, J.S., Chang, P.P., Willerson, J.T., Böger, C.A., Fuchsberger, C., Gao, X., Yang, Q., Schmidt, H., Ketkar, S., Paré, G., Atkinson, E.J., Lohman, K., Cornelis, M.C., Probst-Hensch, N.M., Kronenberg, F., Tönjes, A., Eiriksdottir, G., Launer, L.J., Rampersaud, E., Mitchell, B.D., Struchalin, M., Cavalieri, M., Giallauria, F., Metter, J., de Boer, J., Siscovick, D., Zillikens, M.C., Feitosa, M., Province, M., de Andrade, M., Turner, S.T., Wild, P.S., Schnabel, R.B., Wilde, S., Munzel, T.F., Leak, T.S., Koenig, W., Zgaga, L., Zemunik, T., Kolcic, I., Minelli, C., Hu, F.B., Johansson, A., Zaboli, G., Ellinghaus, D., Imboden, M., Nitsch, D., Brandstätter, A., Kollerits, B., Kedenko, L., Mägi, R., Stumvoll, M., Kovacs, P., Boban, M., Campbell, S., Endlich, K., Nauck, M., Badola, S., Curhan, G.C., Franke, A., Rochat, T., Paulweber, B., Wang, W., Schmidt, R., Shlipak, M.G., Borecki, I., Krämer, B.K., Gyllensten, U., Hastie, N., Heid, I.M., Fox, C.S., Felix, S.B., Watzinger, N., Homuth, G., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R.J., Greiser, K.H., Deckers, J.W., Stritzke, J., Lackner, K.J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M.M., Werdan, K., Mitchell, G.F., Arnett, D.K., Blettner, M., Friedrich, N., Benjamin, E.J., Lord, G.M., Gale, D.P., Wass, M.N., Ahmadi, K.R., Beckmann, J., Bilo, H.J., Cook, H.T., Cotlarciuc, I., Davey Smith, G., de Silva, R., Deng, G., Devuyst, O., Dikkeschei, L.D., Dimkovic, N., Dockrell, M., Dominiczak, A., Ebrahim, S., Eggermann, T., Floege, J., Forouhi, N.G., Gansevoort, R.T., Han, X., Homan van der Heide, J.J., Hepkema, B.G., Hernandez-Fuentes, M., Hypponen, E., de Jong, P.E., Kleefstra, N., Lagou, V., Lapsley, M., Luttropp, K., Maréchal, C., Nordfors, L., Penninx, B.W., Perucha, E., Pouta, A., Roderick, P.J., Ruokonen, A., Sanna, S., Schalling, M., Schlessinger, D., Schlieper, G., Seelen, M.A., Smit, J.H., Stenvinkel, P., Sternberg, M.J., Swaminathan, R., Ubink-Veltmaat, L.J., Wallace, C., Waterworth, D., Zerres, K., Waeber, G., Maxwell, P.H., McCarthy, M.I., Jarvelin, M.R., Lightstone, L., International Consortium for Blood Pressure Genome-Wide Association Studies, CARDIoGRAM consortium, CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, CHARGE-HF consortium, Ehret, G.B., Munroe, P.B., Rice, K.M., Bochud, M., Johnson, A.D., Chasman, D.I., Smith, A.V., Tobin, M.D., Verwoert, G.C., Hwang, S.J., Pihur, V., Vollenweider, P., O'Reilly, P.F., Amin, N., Bragg-Gresham, J.L., Teumer, A., Glazer, N.L., Launer, L., Zhao, J.H., Aulchenko, Y., Heath, S., Sõber, S., Parsa, A., Luan, J., Arora, P., Dehghan, A., Zhang, F., Lucas, G., Hicks, A.A., Jackson, A.U., Peden, J.F., Tanaka, T., Wild, S.H., Rudan, I., Igl, W., Milaneschi, Y., Parker, A.N., Fava, C., Chambers, J.C., Fox, E.R., Kumari, M., Go, M.J., van der Harst, P., Kao, W.H., Sjögren, M., Vinay, D.G., Alexander, M., Tabara, Y., Shaw-Hawkins, S., Whincup, P.H., Liu, Y., Shi, G., Kuusisto, J., Tayo, B., Seielstad, M., Sim, X., Nguyen, K.D., Lehtimäki, T., Matullo, G., Wu, Y., Gaunt, T.R., Onland-Moret, N.C., Cooper, M.N., Platou, C.G., Org, E., Hardy, R., Dahgam, S., Palmen, J., Vitart, V., Braund, P.S., Kuznetsova, T., Uiterwaal, C.S., Adeyemo, A., Palmas, W., Campbell, H., Ludwig, B., Tomaszewski, M., Tzoulaki, I., Palmer, N.D., Aspelund, T., Garcia, M., Chang, Y.P., O'Connell, J.R., Steinle, N.I., Grobbee, D.E., Arking, D.E., Kardia, S.L., Morrison, A.C., Hernandez, D., Najjar, S., McArdle, W.L., Hadley, D., Brown, M.J., Connell, J.M., Hingorani, A.D., Day, I.N., Lawlor, D.A., Beilby, J.P., Lawrence, R.W., Clarke, R., Hopewell, J.C., Ongen, H., Dreisbach, A.W., Li, Y., Young, J.H., Bis, J.C., Kähönen, M., Viikari, J., Adair, L.S., Lee, N.R., Chen, M.H., Olden, M., Pattaro, C., Bolton, J.A., Köttgen, A., Bergmann, S., Mooser, V., Chaturvedi, N., Frayling, T.M., Islam, M., Jafar, T.H., Erdmann, J., Kulkarni, S.R., Bornstein, S.R., Grässler, J., Groop, L., Voight, B.F., Kettunen, J., Howard, P., Taylor, A., Guarrera, S., Ricceri, F., Emilsson, V., Plump, A., Barroso, I., Khaw, K.T., Weder, A.B., Hunt, S.C., Sun, Y.V., Bergman, R.N., Collins, F.S., Bonnycastle, L.L., Scott, L.J., Stringham, H.M., Peltonen, L., Perola, M., Vartiainen, E., Brand, S.M., Staessen, J.A., Wang, T.J., Burton, P.R., Artigas, M.S., Dong, Y., Snieder, H., Wang, X., Zhu, H., Lohman, K.K., Rudock, M.E., Heckbert, S.R., Smith, N.L., Wiggins, K.L., Doumatey, A., Shriner, D., Veldre, G., Viigimaa, M., Kinra, S., Prabhakaran, D., Tripathy, V., Langefeld, C.D., Rosengren, A., Thelle, D.S., Corsi, A.M., Singleton, A., Forrester, T., Hilton, G., McKenzie, C.A., Salako, T., Iwai, N., Kita, Y., Ogihara, T., Ohkubo, T., Okamura, T., Ueshima, H., Umemura, S., Eyheramendy, S., Meitinger, T., Wichmann, H.E., Cho, Y.S., Kim, H.L., Lee, J.Y., Scott, J., Sehmi, J.S., Zhang, W., Hedblad, B., Nilsson, P., Smith, G.D., Wong, A., Narisu, N., Stančáková, A., Raffel, L.J., Yao, J., Kathiresan, S., O'Donnell, C.J., Schwartz, S.M., Ikram, M.A., Longstreth, W.T., Mosley, T.H., Seshadri, S., Shrine, N.R., Wain, L.V., Morken, M.A., Swift, A.J., Laitinen, J., Prokopenko, I., Zitting, P., Cooper, J.A., Humphries, S.E., Danesh, J., Rasheed, A., Goel, A., Hamsten, A., Watkins, H., Bakker, S.J., van Gilst, W.H., Janipalli, C.S., Mani, K.R., Yajnik, C.S., Hofman, A., Mattace-Raso, F.U., Oostra, B.A., Demirkan, A., Isaacs, A., Rivadeneira, F., Lakatta, E.G., Orru, M., Scuteri, A., Ala-Korpela, M., Kangas, A.J., Lyytikäinen, L.P., Soininen, P., Tukiainen, T., Würtz, P., Ong, R.T., Dörr, M., Kroemer, H.K., Völker, U., Völzke, H., Galan, P., Hercberg, S., Lathrop, M., Zelenika, D., Deloukas, P., Mangino, M., Spector, T.D., Zhai, G., Meschia, J.F., Nalls, M.A., Sharma, P., Terzic, J., Kumar, M.V., Denniff, M., Zukowska-Szczechowska, E., Wagenknecht, L.E., Fowkes, F.G., Charchar, F.J., Schwarz, P.E., Hayward, C., Guo, X., Rotimi, C., Bots, M.L., Brand, E., Samani, N.J., Polasek, O., Talmud, P.J., Nyberg, F., Kuh, D., Laan, M., Hveem, K., Palmer, L.J., van der Schouw, Y.T., Casas, J.P., Mohlke, K.L., Vineis, P., Raitakari, O., Ganesh, S.K., Wong, T.Y., Tai, E.S., Cooper, R.S., Laakso, M., Rao, D.C., Harris, T.B., Morris, R.W., Dominiczak, A.F., Kivimaki, M., Marmot, M.G., Miki, T., Saleheen, D., Chandak, G.R., Coresh, J., Navis, G., Salomaa, V., Han, B.G., Zhu, X., Kooner, J.S., Melander, O., Ridker, P.M., Bandinelli, S., Gyllensten, U.B., Wright, A.F., Wilson, J.F., Ferrucci, L., Farrall, M., Tuomilehto, J., Pramstaller, P.P., Elosua, R., Soranzo, N., Sijbrands, E.J., Altshuler, D., Loos, R.J., Shuldiner, A.R., Gieger, C., Meneton, P., Uitterlinden, A.G., Wareham, N.J., Gudnason, V., Rotter, J.I., Rettig, R., Uda, M., Strachan, D.P., Witteman, J.C., Hartikainen, A.L., Beckmann, J.S., Boerwinkle, E., Vasan, R.S., Boehnke, M., Larson, M.G., Järvelin, M.R., Psaty, B.M., Abecasis, G.R., Chakravarti, A., Elliott, P., van Duijn, C.M., Newton-Cheh, C., Levy, D., Caulfield, M.J., Johnson, T., Tang, H., Knowles, J., Hlatky, M., Fortmann, S., Assimes, T.L., Quertermous, T., Go, A., Iribarren, C., Absher, D., Risch, N., Myers, R., Sidney, S., Ziegler, A., Schillert, A., Bickel, C., Sinning, C., Rupprecht, H.J., Lackner, K., Wild, P., Schnabel, R., Blankenberg, S., Zeller, T., Münzel, T., Perret, C., Cambien, F., Tiret, L., Nicaud, V., Proust, C., Uitterlinden, A., van Duijn, C., Whitteman, J., Cupples, L.A., Demissie-Banjaw, S., Ramachandran, V., Smith, A., Folsom, A., Morrison, A., Chen, I.Y., Bis, J., Volcik, K., Rice, K., Taylor, K.D., Marciante, K., Smith, N., Glazer, N., Heckbert, S., Harris, T., Lumley, T., Kong, A., Thorleifsson, G., Thorgeirsson, G., Holm, H., Gulcher, J.R., Stefansson, K., Andersen, K., Gretarsdottir, S., Thorsteinsdottir, U., Preuss, M., Schreiber, S., König, I.R., Lieb, W., Hengstenberg, C., Schunkert, H., Fischer, M., Grosshennig, A., Medack, A., Stark, K., Linsel-Nitschke, P., Bruse, P., Aherrahrou, Z., Peters, A., Loley, C., Willenborg, C., Nahrstedt, J., Freyer, J., Gulde, S., Doering, A., Meisinger, C., Klopp, N., Illig, T., Meinitzer, A., Tomaschitz, A., Halperin, E., Dobnig, H., Scharnagl, H., Kleber, M., Laaksonen, R., Pilz, S., Grammer, T.B., Stojakovic, T., Renner, W., März, W., Böhm, B.O., Winkelmann, B.R., Winkler, K., Hoffmann, M.M., Siscovick, D.S., Musunuru, K., Barbalic, M., Guiducci, C., Burtt, N., Gabriel, S.B., Stewart, A.F., Wells, G.A., Chen, L., Jarinova, O., Roberts, R., McPherson, R., Dandona, S., Pichard, A.D., Rader, D.J., Devaney, J., Lindsay, J.M., Kent, K.M., Qu, L., Satler, L., Burnett, M.S., Li, M., Reilly, M.P., Wilensky, R., Waksman, R., Epstein, S., Matthai, W., Knouff, C.W., Waterworth, D.M., Hakonarson, H.H., Walker, M.C., Hall, A.S., Balmforth, A.J., Wright, B.J., Nelson, C., Thompson, J.R., Ball, S.G., Felix, J.F., Demissie, S., Loehr, L.R., Rosamond, W.D., Folsom, A.R., Benjamin, E., Aulchenko, Y.S., Haritunians, T., Couper, D., Murabito, J., Wang, Y.A., Stricker, B.H., Gottdiener, J.S., Chang, P.P., Willerson, J.T., Böger, C.A., Fuchsberger, C., Gao, X., Yang, Q., Schmidt, H., Ketkar, S., Paré, G., Atkinson, E.J., Lohman, K., Cornelis, M.C., Probst-Hensch, N.M., Kronenberg, F., Tönjes, A., Eiriksdottir, G., Launer, L.J., Rampersaud, E., Mitchell, B.D., Struchalin, M., Cavalieri, M., Giallauria, F., Metter, J., de Boer, J., Siscovick, D., Zillikens, M.C., Feitosa, M., Province, M., de Andrade, M., Turner, S.T., Wild, P.S., Schnabel, R.B., Wilde, S., Munzel, T.F., Leak, T.S., Koenig, W., Zgaga, L., Zemunik, T., Kolcic, I., Minelli, C., Hu, F.B., Johansson, A., Zaboli, G., Ellinghaus, D., Imboden, M., Nitsch, D., Brandstätter, A., Kollerits, B., Kedenko, L., Mägi, R., Stumvoll, M., Kovacs, P., Boban, M., Campbell, S., Endlich, K., Nauck, M., Badola, S., Curhan, G.C., Franke, A., Rochat, T., Paulweber, B., Wang, W., Schmidt, R., Shlipak, M.G., Borecki, I., Krämer, B.K., Gyllensten, U., Hastie, N., Heid, I.M., Fox, C.S., Felix, S.B., Watzinger, N., Homuth, G., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R.J., Greiser, K.H., Deckers, J.W., Stritzke, J., Lackner, K.J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M.M., Werdan, K., Mitchell, G.F., Arnett, D.K., Blettner, M., Friedrich, N., Benjamin, E.J., Lord, G.M., Gale, D.P., Wass, M.N., Ahmadi, K.R., Beckmann, J., Bilo, H.J., Cook, H.T., Cotlarciuc, I., Davey Smith, G., de Silva, R., Deng, G., Devuyst, O., Dikkeschei, L.D., Dimkovic, N., Dockrell, M., Dominiczak, A., Ebrahim, S., Eggermann, T., Floege, J., Forouhi, N.G., Gansevoort, R.T., Han, X., Homan van der Heide, J.J., Hepkema, B.G., Hernandez-Fuentes, M., Hypponen, E., de Jong, P.E., Kleefstra, N., Lagou, V., Lapsley, M., Luttropp, K., Maréchal, C., Nordfors, L., Penninx, B.W., Perucha, E., Pouta, A., Roderick, P.J., Ruokonen, A., Sanna, S., Schalling, M., Schlessinger, D., Schlieper, G., Seelen, M.A., Smit, J.H., Stenvinkel, P., Sternberg, M.J., Swaminathan, R., Ubink-Veltmaat, L.J., Wallace, C., Waterworth, D., Zerres, K., Waeber, G., Maxwell, P.H., McCarthy, M.I., Jarvelin, M.R., and Lightstone, L.
Abstract: Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm Hg systolic blood pressure or ≥90 mm Hg diastolic blood pressure). Even small increments in blood pressure are associated with an increased risk of cardiovascular events. This genome-wide association study of systolic and diastolic blood pressure, which used a multi-stage design in 200,000 individuals of European descent, identified sixteen novel loci: six of these loci contain genes previously known or suspected to regulate blood pressure (GUCY1A3-GUCY1B3, NPR3-C5orf23, ADM, FURIN-FES, GOSR2, GNAS-EDN3); the other ten provide new clues to blood pressure physiology. A genetic risk score based on 29 genome-wide significant variants was associated with hypertension, left ventricular wall thickness, stroke and coronary artery disease, but not kidney disease or kidney function. We also observed associations with blood pressure in East Asian, South Asian and African ancestry individuals. Our findings provide new insights into the genetics and biology of blood pressure, and suggest potential novel therapeutic pathways for cardiovascular disease prevention.
Published: 2011

12. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Author: Ehret, G.B. (Georg), Munroe, P. (Patricia), Rice, K.M. (Kenneth), Bochud, M. (Murielle), Johnson, A.D. (Andrew), Chasman, D.I. (Daniel), Smith, A.V. (Albert Vernon), Tobin, M.D. (Martin), Verwoert, G.C. (Germaine), Hwang, S.J., Pihur, V. (Vasyl), Vollenweider, P. (Peter), O'Reilly, P.F. (Paul), Amin, N. (Najaf), Bragg-Gresham, J.L. (Jennifer L.), Teumer, A. (Alexander), Glazer, N.L. (Nicole), Launer, L.J. (Lenore), Zhao, J.H. (Jing Hua), Aulchenko, Y.S. (Yurii), Heath, S.C. (Simon), Sõber, S. (Siim), Parsa, A. (Afshin), Luan, J., Arora, P. (Pankaj), Dehghan, A. (Abbas), Zhang, F. (Feng), Lucas, G. (Gavin), Hicks, A.A. (Andrew), Jackson, A.U. (Anne), Peden, J. (John), Tanaka, T. (Toshiko), Wild, S.H. (Sarah), Rudan, I. (Igor), Igl, W. (Wilmar), Milaneschi, Y. (Yuri), Parker, A.N. (Alex), Fava, C. (Cristiano), Chambers, J.C. (John), Fox, E.R. (Ervin), Kumari, M. (Meena), Jin Go, M. (Min), Harst, P. (Pim) van der, Kao, W.-H.L. (Wen-Hong Linda), Sjögren, M. (Marketa), Vinay, D.G., Alexander, M. (Myriam), Tabara, Y. (Yasuharu), Shaw-Hawkins, S. (Sue), Whincup, P.H. (Peter), Liu, Y. (YongMei), Shi, G. (Gang), Kuusisto, J. (Johanna), Tayo, B. (Bamidele), Seielstad, M. (Mark), Sim, X. (Xueling), Hoang Nguyen, K.-D., Lehtimäki, T. (Terho), Matullo, G. (Giuseppe), Wu, Y. (Ying), Gaunt, T.R. (Tom), Onland-Moret, N.C. (Charlotte), Cooper, M.N. (Matthew), Platou, C. (Carl), Org, E. (Elin), Hardy, R. (Rebecca), Dahgam, S. (Santosh), Palmen, J. (Jutta), Vitart, V. (Veronique), Braund, P.S. (Peter), Kuznetsova, T. (Tatiana), Uiterwaal, C.S.P.M. (Cuno), Adeyemo, A. (Adebowale), Palmas, W. (Walter), Campbell, H. (Harry), Ludwig, B. (Barbara), Tomaszewski, M., Tzoulaki, I., Palmer, N.D. (Nicholette), Aspelund, T. (Thor), Garcia, M. (Melissa), Chang, Y.-P.C. (Yen-Pei), O´Connell, J.R., Steinle, N.I. (Nanette), Grobbee, D.E. (Diederick), Arking, D.E. (Dan), Kardia, S.L. (Sharon), Morrison, A.C. (Alanna), Hernandez, D.G. (Dena), Najjar, S.S. (Samer), McArdle, W.L. (Wendy), Hadley, D. (David), Brown, M.J. (Morris), Connell, J. (John), Hingorani, A. (Aroon), Day, I.N.M. (Ian), Lawlor, D.A. (Debbie), Beilby, J.P. (John), Lawrence, R.W. (Robert), Clarke, R., Hopewell, J., Ongen, H. (Halit), Dreisbach, A.W. (Albert), Li, Y. (Yali), Hunter Young, J., Bis, J.C. (Joshua), Kähönen, M. (Mika), Viikari, J. (Jorma), Lee, N.R. (Nanette), Chen, M-H. (Ming-Huei), Olden, M. (Matthias), Pattaro, C. (Cristian), Hoffman Bolton, J.A. (Judith), Köttgen, A. (Anna), Bergmann, S.M. (Sven), Mooser, V. (Vincent), Chaturvedi, N. (Nish), Frayling, T.M. (Timothy), Islam, M. (Muhammad), Jafar, T.H. (Tazeen), Kulkarni, S.R. (Smita), Bornstein, S.R. (Stefan), Gräßler, J. (Jürgen), Groop, L. (Leif), Voight, B.F. (Benjamin), Kettunen, J. (Johannes), Howard, P. (Philip), Taylor, A. (Andrew), Guarrera, S. (Simonetta), Ricceri, F. (Fulvio), Emilsson, V. (Valur), Plump, A.S. (Andrew), Khaw, K-T. (Kay-Tee), Weder, A.B. (Alan), Hunt, S.C. (Steven), Sun, Y.V. (Yan), Bergman, R.N. (Richard), Collins, F.S. (Francis), Bonnycastle, L.L. (Lori), Scott, L.J. (Laura), Stringham, H.M. (Heather), Peltonen, L. (Leena Johanna), Perola, M. (Markus), Vartiainen, E. (Erkki), Brand, S.-M., Staessen, J.A. (Jan), Wang, Y.A. (Ying), Burton, P.R. (Paul), Soler Artigas, M. (Maria), Dong, Y. (Yanbin), Snieder, H. (Harold), Zhu, H. (Haidong), Lohman, K. (Kurt), Rudock, M.E. (Megan), Heckbert, S.R. (Susan), Wiggins, K.L. (Kerri), Doumatey, A. (Ayo), Shriner, D. (Daniel), Veldre, G. (Gudrun), Viigimaa, M. (Margus), Kinra, S. (Sanjay), Prabhakaran, D. (Dorairaj), Tripathy, V. (Vikal), Langefeld, C.D. (Carl), Rosengren, A. (Annika), Thelle, D.S. (Dag), Corsi, A.M. (Anna Maria), Singleton, A. (Andrew), Forrester, T. (Terrence), Hilton, G. (Gina), McKenzie, C.A. (Colin), Salako, T. (Tunde), Iwai, N. (Naoharu), Kita, Y. (Yoshikuni), Ogihara, T. (Toshio), Ohkubo, T. (Takayoshi), Okamura, T. (Tomonori), Ueshima, H. (Hirotsugu), Umemura, S. (Satoshi), Eyheramendy, S. (Susana), Meitinger, T. (Thomas), Wichmann, H.E. (Heinz Erich), Shin Cho, Y. (Yoon), Kim, H.-L., Sehmi, J.S. (Joban), Hedblad, B. (Bo), Nilsson, P. (Peter), Davey-Smith, G. (George), Wong, A. (Andrew), Narisu, N. (Narisu), Stancáková, A. (Alena), Raffel, L.J. (Leslie), Yao, J. (Jie), Kathiresan, S. (Sekar), O'Donnell, C.J. (Christopher), Schwartz, S.M. (Stephen), Ikram, M.A. (Arfan), Longstreth Jr, W.T., Mosley, T.H. (Thomas), Seshadri, S. (Sudha), Shrine, N.R.G. (Nick), Wain, L.V. (Louise), Morken, M.A. (Mario), Swift, A.J. (Amy), Laitinen, J. (Jaana), Prokopenko, I. (Inga), Zitting, P. (Paavo), Humphries, S.E. (Steve), Danesh, J. (John), Rasheed, A. (Asif), Goel, A. (Anuj), Hamsten, A. (Anders), Watkins, H. (Hugh), Gilst, W.H. (Wiek) van, Janipalli, C.S. (Charles), Radha Mani, K., Yajnik, C. (Chittaranjan), Hofman, A. (Albert), Mattace Raso, F.U.S. (Francesco), Oostra, B.A. (Ben), Demirkan, A. (Ayşe), Isaacs, A.J. (Aaron), Rivadeneira Ramirez, F. (Fernando), Lakatta, E. (Edward), Orrù, M. (Marco), Scuteri, A. (Angelo), Ala-Korpela, M. (Mika), Kangas, A.J. (Antti), Lyytikäinen, L.-P. (Leo-Pekka), Soininen, P. (Pasi), Tukiainen, T. (Taru), Würtz, P. (Peter), Twee-Hee Ong, R. (Rick), Dörr, M. (Marcus), Kroemer, H.K. (Heyo), Völker, U. (Uwe), Völzke, H. (Henry), Galan, P. (Pilar), Hercberg, S. (Serge), Lathrop, G.M. (Mark), Zelenika, D. (Diana), Deloukas, P. (Panagiotis), Mangino, M. (Massimo), Spector, T.D. (Timothy), Zhai, G. (Guangju), Meschia, J.F. (James F.), Nalls, M.A. (Michael), Sharma, P. (Pankaj), Terzic, J. (Janos), Kranthi Kumar, M.V., Denniff, M. (Matthew), Zukowska-Szczechowska, E. (Ewa), Wagenknecht, L.E. (Lynne), Fowkes, F.G.R. (Gerald), Charchar, F.J. (Fadi), Schwarz, P.E.H. (Peter), Hayward, C. (Caroline), Guo, X. (Xiuqing), Rotimi, C. (Charles), Bots, M.L. (Michiel), Samani, N.J. (Nilesh), Polasek, O. (Ozren), Talmud, P.J. (Philippa), Nyberg, F. (Fredrik), Kuh, D. (Diana), Laan, M. (Maris), Hveem, K. (Kristian), Schouw, Y.T. (Yvonne) van der, Casas, J.P. (Juan), Mohlke, K.L. (Karen), Vineis, P. (Paolo), Raitakari, O. (Olli), Ganesh, S.K. (Santhi), Shyong Tai, E., Laakso, M. (Markku), Rao, D.C. (Dabeeru C.), Harris, T.B. (Tamara), Morris, R.W. (Richard), Dominiczak, A. (Anna), Kivimaki, M. (Mika), Marmot, M. (Michael), Miki, T. (Tetsuro), Saleheen, D., Chandak, G.R. (Giriraj), Coresh, J. (Josef), Navis, G. (Gerjan), Salomaa, V. (Veikko), Han, B.-G., Kooner, J.S. (Jaspal), Melander, O. (Olle), Ridker, P.M. (Paul), Bandinelli, S. (Stefania), Gyllensten, U. (Ulf), Wright, A.F. (Alan), Wilson, J.F. (James), Ferrucci, L. (Luigi), Farrall, M. (Martin), Tuomilehto, J. (Jaakko), Pramstaller, P.P. (Peter Paul), Elosua, R. (Roberto), Soranzo, N. (Nicole), Sijbrands, E.J.G. (Eric), Altshuler, D. (David), Loos, R.J.F. (Ruth), Shuldiner, A.R. (Alan), Gieger, C. (Christian), Meneton, P. (Pierre), Uitterlinden, A.G. (André), Wareham, N.J. (Nick), Gudnason, V. (Vilmundur), Rotter, J.I. (Jerome), Rettig, R. (Rainer), Uda, M. (Manuela), Strachan, D.P. (David), Witteman, J.C.M. (Jacqueline), Hartikainen, A.L., Beckmann, J.S. (Jacques), Boerwinkle, E.A. (Eric), Erdmann, J. (Jeanette), Vasan, R.S. (Ramachandran Srini), Boehnke, M. (Michael), Larson, M.G. (Martin), Järvelin, M.R., Psaty, B.M. (Bruce), Tikka-Kleemola, P. (Päivi), Newton-Cheh, C. (Christopher), Elliott, P. (Paul), Levy, D. (Daniel), Caulfield, M. (Mark), Abecasis, G.R. (Gonçalo), Adair, L.S. (Linda), Bakker, S.J.L. (Stephan), Barroso, I.E. (Inês), Ehret, G.B. (Georg), Munroe, P. (Patricia), Rice, K.M. (Kenneth), Bochud, M. (Murielle), Johnson, A.D. (Andrew), Chasman, D.I. (Daniel), Smith, A.V. (Albert Vernon), Tobin, M.D. (Martin), Verwoert, G.C. (Germaine), Hwang, S.J., Pihur, V. (Vasyl), Vollenweider, P. (Peter), O'Reilly, P.F. (Paul), Amin, N. (Najaf), Bragg-Gresham, J.L. (Jennifer L.), Teumer, A. (Alexander), Glazer, N.L. (Nicole), Launer, L.J. (Lenore), Zhao, J.H. (Jing Hua), Aulchenko, Y.S. (Yurii), Heath, S.C. (Simon), Sõber, S. (Siim), Parsa, A. (Afshin), Luan, J., Arora, P. (Pankaj), Dehghan, A. (Abbas), Zhang, F. (Feng), Lucas, G. (Gavin), Hicks, A.A. (Andrew), Jackson, A.U. (Anne), Peden, J. (John), Tanaka, T. (Toshiko), Wild, S.H. (Sarah), Rudan, I. (Igor), Igl, W. (Wilmar), Milaneschi, Y. (Yuri), Parker, A.N. (Alex), Fava, C. (Cristiano), Chambers, J.C. (John), Fox, E.R. (Ervin), Kumari, M. (Meena), Jin Go, M. (Min), Harst, P. (Pim) van der, Kao, W.-H.L. (Wen-Hong Linda), Sjögren, M. (Marketa), Vinay, D.G., Alexander, M. (Myriam), Tabara, Y. (Yasuharu), Shaw-Hawkins, S. (Sue), Whincup, P.H. (Peter), Liu, Y. (YongMei), Shi, G. (Gang), Kuusisto, J. (Johanna), Tayo, B. (Bamidele), Seielstad, M. (Mark), Sim, X. (Xueling), Hoang Nguyen, K.-D., Lehtimäki, T. (Terho), Matullo, G. (Giuseppe), Wu, Y. (Ying), Gaunt, T.R. (Tom), Onland-Moret, N.C. (Charlotte), Cooper, M.N. (Matthew), Platou, C. (Carl), Org, E. (Elin), Hardy, R. (Rebecca), Dahgam, S. (Santosh), Palmen, J. (Jutta), Vitart, V. (Veronique), Braund, P.S. (Peter), Kuznetsova, T. (Tatiana), Uiterwaal, C.S.P.M. (Cuno), Adeyemo, A. (Adebowale), Palmas, W. (Walter), Campbell, H. (Harry), Ludwig, B. (Barbara), Tomaszewski, M., Tzoulaki, I., Palmer, N.D. (Nicholette), Aspelund, T. (Thor), Garcia, M. (Melissa), Chang, Y.-P.C. (Yen-Pei), O´Connell, J.R., Steinle, N.I. (Nanette), Grobbee, D.E. (Diederick), Arking, D.E. (Dan), Kardia, S.L. (Sharon), Morrison, A.C. (Alanna), Hernandez, D.G. (Dena), Najjar, S.S. (Samer), McArdle, W.L. (Wendy), Hadley, D. (David), Brown, M.J. (Morris), Connell, J. (John), Hingorani, A. (Aroon), Day, I.N.M. (Ian), Lawlor, D.A. (Debbie), Beilby, J.P. (John), Lawrence, R.W. (Robert), Clarke, R., Hopewell, J., Ongen, H. (Halit), Dreisbach, A.W. (Albert), Li, Y. (Yali), Hunter Young, J., Bis, J.C. (Joshua), Kähönen, M. (Mika), Viikari, J. (Jorma), Lee, N.R. (Nanette), Chen, M-H. (Ming-Huei), Olden, M. (Matthias), Pattaro, C. (Cristian), Hoffman Bolton, J.A. (Judith), Köttgen, A. (Anna), Bergmann, S.M. (Sven), Mooser, V. (Vincent), Chaturvedi, N. (Nish), Frayling, T.M. (Timothy), Islam, M. (Muhammad), Jafar, T.H. (Tazeen), Kulkarni, S.R. (Smita), Bornstein, S.R. (Stefan), Gräßler, J. (Jürgen), Groop, L. (Leif), Voight, B.F. (Benjamin), Kettunen, J. (Johannes), Howard, P. (Philip), Taylor, A. (Andrew), Guarrera, S. (Simonetta), Ricceri, F. (Fulvio), Emilsson, V. (Valur), Plump, A.S. (Andrew), Khaw, K-T. (Kay-Tee), Weder, A.B. (Alan), Hunt, S.C. (Steven), Sun, Y.V. (Yan), Bergman, R.N. (Richard), Collins, F.S. (Francis), Bonnycastle, L.L. (Lori), Scott, L.J. (Laura), Stringham, H.M. (Heather), Peltonen, L. (Leena Johanna), Perola, M. (Markus), Vartiainen, E. (Erkki), Brand, S.-M., Staessen, J.A. (Jan), Wang, Y.A. (Ying), Burton, P.R. (Paul), Soler Artigas, M. (Maria), Dong, Y. (Yanbin), Snieder, H. (Harold), Zhu, H. (Haidong), Lohman, K. (Kurt), Rudock, M.E. (Megan), Heckbert, S.R. (Susan), Wiggins, K.L. (Kerri), Doumatey, A. (Ayo), Shriner, D. (Daniel), Veldre, G. (Gudrun), Viigimaa, M. (Margus), Kinra, S. (Sanjay), Prabhakaran, D. (Dorairaj), Tripathy, V. (Vikal), Langefeld, C.D. (Carl), Rosengren, A. (Annika), Thelle, D.S. (Dag), Corsi, A.M. (Anna Maria), Singleton, A. (Andrew), Forrester, T. (Terrence), Hilton, G. (Gina), McKenzie, C.A. (Colin), Salako, T. (Tunde), Iwai, N. (Naoharu), Kita, Y. (Yoshikuni), Ogihara, T. (Toshio), Ohkubo, T. (Takayoshi), Okamura, T. (Tomonori), Ueshima, H. (Hirotsugu), Umemura, S. (Satoshi), Eyheramendy, S. (Susana), Meitinger, T. (Thomas), Wichmann, H.E. (Heinz Erich), Shin Cho, Y. (Yoon), Kim, H.-L., Sehmi, J.S. (Joban), Hedblad, B. (Bo), Nilsson, P. (Peter), Davey-Smith, G. (George), Wong, A. (Andrew), Narisu, N. (Narisu), Stancáková, A. (Alena), Raffel, L.J. (Leslie), Yao, J. (Jie), Kathiresan, S. (Sekar), O'Donnell, C.J. (Christopher), Schwartz, S.M. (Stephen), Ikram, M.A. (Arfan), Longstreth Jr, W.T., Mosley, T.H. (Thomas), Seshadri, S. (Sudha), Shrine, N.R.G. (Nick), Wain, L.V. (Louise), Morken, M.A. (Mario), Swift, A.J. (Amy), Laitinen, J. (Jaana), Prokopenko, I. (Inga), Zitting, P. (Paavo), Humphries, S.E. (Steve), Danesh, J. (John), Rasheed, A. (Asif), Goel, A. (Anuj), Hamsten, A. (Anders), Watkins, H. (Hugh), Gilst, W.H. (Wiek) van, Janipalli, C.S. (Charles), Radha Mani, K., Yajnik, C. (Chittaranjan), Hofman, A. (Albert), Mattace Raso, F.U.S. (Francesco), Oostra, B.A. (Ben), Demirkan, A. (Ayşe), Isaacs, A.J. (Aaron), Rivadeneira Ramirez, F. (Fernando), Lakatta, E. (Edward), Orrù, M. (Marco), Scuteri, A. (Angelo), Ala-Korpela, M. (Mika), Kangas, A.J. (Antti), Lyytikäinen, L.-P. (Leo-Pekka), Soininen, P. (Pasi), Tukiainen, T. (Taru), Würtz, P. (Peter), Twee-Hee Ong, R. (Rick), Dörr, M. (Marcus), Kroemer, H.K. (Heyo), Völker, U. (Uwe), Völzke, H. (Henry), Galan, P. (Pilar), Hercberg, S. (Serge), Lathrop, G.M. (Mark), Zelenika, D. (Diana), Deloukas, P. (Panagiotis), Mangino, M. (Massimo), Spector, T.D. (Timothy), Zhai, G. (Guangju), Meschia, J.F. (James F.), Nalls, M.A. (Michael), Sharma, P. (Pankaj), Terzic, J. (Janos), Kranthi Kumar, M.V., Denniff, M. (Matthew), Zukowska-Szczechowska, E. (Ewa), Wagenknecht, L.E. (Lynne), Fowkes, F.G.R. (Gerald), Charchar, F.J. (Fadi), Schwarz, P.E.H. (Peter), Hayward, C. (Caroline), Guo, X. (Xiuqing), Rotimi, C. (Charles), Bots, M.L. (Michiel), Samani, N.J. (Nilesh), Polasek, O. (Ozren), Talmud, P.J. (Philippa), Nyberg, F. (Fredrik), Kuh, D. (Diana), Laan, M. (Maris), Hveem, K. (Kristian), Schouw, Y.T. (Yvonne) van der, Casas, J.P. (Juan), Mohlke, K.L. (Karen), Vineis, P. (Paolo), Raitakari, O. (Olli), Ganesh, S.K. (Santhi), Shyong Tai, E., Laakso, M. (Markku), Rao, D.C. (Dabeeru C.), Harris, T.B. (Tamara), Morris, R.W. (Richard), Dominiczak, A. (Anna), Kivimaki, M. (Mika), Marmot, M. (Michael), Miki, T. (Tetsuro), Saleheen, D., Chandak, G.R. (Giriraj), Coresh, J. (Josef), Navis, G. (Gerjan), Salomaa, V. (Veikko), Han, B.-G., Kooner, J.S. (Jaspal), Melander, O. (Olle), Ridker, P.M. (Paul), Bandinelli, S. (Stefania), Gyllensten, U. (Ulf), Wright, A.F. (Alan), Wilson, J.F. (James), Ferrucci, L. (Luigi), Farrall, M. (Martin), Tuomilehto, J. (Jaakko), Pramstaller, P.P. (Peter Paul), Elosua, R. (Roberto), Soranzo, N. (Nicole), Sijbrands, E.J.G. (Eric), Altshuler, D. (David), Loos, R.J.F. (Ruth), Shuldiner, A.R. (Alan), Gieger, C. (Christian), Meneton, P. (Pierre), Uitterlinden, A.G. (André), Wareham, N.J. (Nick), Gudnason, V. (Vilmundur), Rotter, J.I. (Jerome), Rettig, R. (Rainer), Uda, M. (Manuela), Strachan, D.P. (David), Witteman, J.C.M. (Jacqueline), Hartikainen, A.L., Beckmann, J.S. (Jacques), Boerwinkle, E.A. (Eric), Erdmann, J. (Jeanette), Vasan, R.S. (Ramachandran Srini), Boehnke, M. (Michael), Larson, M.G. (Martin), Järvelin, M.R., Psaty, B.M. (Bruce), Tikka-Kleemola, P. (Päivi), Newton-Cheh, C. (Christopher), Elliott, P. (Paul), Levy, D. (Daniel), Caulfield, M. (Mark), Abecasis, G.R. (Gonçalo), Adair, L.S. (Linda), Bakker, S.J.L. (Stephan), and Barroso, I.E. (Inês)
Abstract: Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140mmg Hg systolic blood pressure ≥90mmg Hg diastolic blood pressure). Even small increments in blood pressure are associated with an increased risk of cardiovascular events. This genome-wide association study of systolic and diastolic blood pressure, which used a multi-stage design in 200,000 individuals of European descent, identified sixteen novel loci: six of these loci contain genes previously known or suspected to regulate blood pressure (GUCY1A3 GUCY1B3, NPR3 C5orf23, ADM, FURIN FES, GOSR2, GNAS EDN3); the other ten provide new clues to blood pressure physiology. A genetic risk score based on 29 geno
Published: 2011
Full Text: View/download PDF

13. Mapping the human genetic architecture of COVID-19

Author: Niemi, MEK, Karjalainen, J, Liao, RG, Neale, BM, Daly, M, Ganna, A, Pathak, GA, Andrews, SJ, Kanai, M, Veerapen, K, Fernandez-Cadenas, I, Schulte, EC, Striano, P, Marttila, M, Minica, C, Marouli, E, Karim, MA, Wendt, FR, Savage, J, Sloofman, L, Butler-Laporte, G, Kim, H-N, Kanoni, S, Okada, Y, Byun, J, Han, Y, Uddin, MJ, Smith, GD, Willer, CJ, Buxbaum, JD, Mehtonen, J, Finucane, H, Cordioli, M, Martin, AR, Zhou, W, Pasaniuc, B, Julienne, H, Aschard, H, Shi, H, Yengo, L, Polimanti, R, Ghoussaini, M, Schwartzentruber, J, Dunham, I, Chwialkowska, K, Francescatto, M, Trankiem, A, Balaconis, MK, Davis, L, Lee, S, Priest, J, Renieri, A, Sankaran, VG, van Heel, D, Deelen, P, Richards, JB, Nakanishi, T, Biesecker, L, Kerchberger, VE, Kenneth, J, Mari, F, Bernasconi, A, Ceri, S, Canakoglu, A, Wolford, B, Faucon, A, Dutta, AK, Schurmann, C, Harry, E, Birney, E, Nguyen, H, Nasir, J, Kaunisto, M, Solomonson, M, Dueker, N, Vadgama, N, Limou, S, Rahmouni, S, Mbarek, H, Darwish, D, Uddin, MM, Albertos, R, Perez-Tur, J, Li, R, Folkersen, L, Moltke, I, Koelling, N, Teumer, A, Kousathanas, A, Utrilla, A, Verdugo, RA, Zarate, R, Medina-Gomez, C, Gomez-Cabrero, D, Carnero-Montoro, E, Cadilla, CL, Moreno-Estrada, A, Garmendia, A, Moya, L, Sedaghati-Khayat, B, Boua, PR, Fave, M-J, Francioli, L, Lemacon, A, Migeotte, I, Patel, S, Varnai, R, Szentpeteri, JL, Sipeky, C, Colombo, F, von Hohenstaufen, K, Lio, P, Vallerga, C, Wang, Q, Tanigawa, Y, Im, H, Han, C, Song, H, Lim, J, Lee, Y, Kim, S, Im, S, Atanasovska, B, Ahmad, HF, Boer, C, Jansen, P, Franke, L, Kaja, E, Pasko, D, Kennis-Szilagyi, I, Kornilov, SA, Prijatelj, V, Prokic, I, Sivanadhan, I, Perumal, S, Esmaeeli, S, Pearson, NM, Auton, A, Shelton, JF, Shastri, AJ, Filshtein-Sonmez, T, Coker, D, Symons, A, Esparza-Gordillo, J, Aslibekyan, S, O'Connell, J, Ye, C, Weldon, CH, Perera, M, O'Leary, K, Tuck, M, O'Brien, T, Meltzer, D, O'Donnell, P, Nutescu, E, Yang, G, Alarcon, C, Herrmann, S, Mazurek, S, Banagan, J, Hamidi, Z, Barbour, A, Raffat, N, Moreno, D, Friedman, P, Ferwerda, B, van de Beek, D, Brouwer, MC, Vlaar, APJ, Wiersinga, WJ, Posthuma, D, Tissink, E, Zwinderman, AHK, Uffelmann, E, van Agtmael, M, Algera, AG, van Baarle, F, Bax, D, Beudel, M, Bogaard, HJ, Bomers, M, Bonta, PI, Bos, L, Botta, M, de Brabander, J, de Bree, G, de Bruin, S, Bugiani, M, Bulle, E, Chouchane, O, Cloherty, A, Dongelmans, D, Elbers, P, Fleuren, L, Geerlings, S, Geerts, B, Geijtenbeek, T, Girbes, A, Goorhuis, B, Grobusch, MP, Hafkamp, F, Hagens, L, Hamann, J, Harris, V, Hemke, R, Hermans, SM, Heunks, L, Hollmann, M, Horn, J, Hovius, JW, de Jong, MD, Koning, R, van Mourik, N, Nellen, J, Nossent, EJ, Paulus, F, Peters, E, van der Poll, T, Preckel, B, Prins, JM, Raasveld, J, Reijnders, T, Schinkel, M, Schultz, MJ, Schuurman, A, Sigaloff, K, Smit, M, Stijnis, CS, Stilma, W, Teunissen, C, Thoral, P, Tsonas, A, van der Valk, M, Veelo, D, de Vries, H, van Vugt, M, Wouters, D, Minnaar, RP, Kromhout, A, van Uffelen, KWJ, Wolterman, RA, Roberts, G, Park, D, Ball, CA, Coignet, M, McCurdy, S, Knight, S, Partha, R, Rhead, B, Zhang, M, Berkowitz, N, Gaddis, M, Noto, K, Ruiz, L, Pavlovic, M, Hong, EL, Rand, K, Girshick, A, Guturu, H, Baltzell, AH, Guntz, J, Beguin, Y, Pigazzini, S, Nkambule, L, Bouysran, Y, Busson, A, Peyrassol, X, Wilkin, F, Pichon, B, Smits, G, Vandernoot, I, Goffard, J-C, Georges, M, Moutschen, M, Misset, B, Darcis, G, Guiot, J, Jadot, L, Azarzar, S, Dellot, P, Gofflot, S, Claassen, S, Bertrand, A, Parzibut, G, Clarinval, M, Moermans, C, Malaise, O, El Kandoussi, K, Thonon, R, Huynen, P, Mesdagh, A, Melo, S, Jacques, N, Di Valentin, E, Giroule, F, Collignon, A, Radermecker, C, Lebrun, M, Peree, H, Latour, S, Barada, O, Sanchez, J, Josse, C, Boujemla, B, Meunier, M, Mariavelle, E, Anania, S, Gazon, H, Juszczak, D, Fadeur, M, Camby, S, Meuris, C, Thys, M, Jacques, J, Henket, M, Leonard, P, Frippiat, F, Giot, J-B, Sauvage, A-S, Von Frenckell, C, Mni, M, Wery, M, Staderoli, A, Belhaj, Y, Lambermont, B, Morrison, DR, Mooser, V, Forgetta, V, Ghosh, B, Laurent, L, Belisle, A, Henry, D, Abdullah, T, Adeleye, O, Mamlouk, N, Kimchi, N, Afrasiabi, Z, Rezk, N, Vulesevic, B, Bouab, M, Guzman, C, Petitjean, L, Tselios, C, Xue, X, Afilalo, J, Afilalo, M, Oliveira, M, Brenner, B, Brassard, N, Durand, M, Schurr, E, Lepage, P, Ragoussis, J, Auld, D, Chasse, M, Kaufmann, DE, Lathrop, GM, Adra, D, Davis, LK, Cox, NJ, Below, JE, Sealock, JM, Faucon, AB, Shuey, MM, Polikowsky, HG, Petty, LE, Shaw, DM, Chen, H-H, Zhu, W, Ludwig, KU, Schroeder, J, Maj, C, Rolker, S, Noethen, MM, Fazaal, J, Keitel, V, Jensen, B-EO, Feldt, T, Kurth, I, Marx, N, Dreher, M, Pink, I, Cornberg, M, Illig, T, Lehmann, C, Schommers, P, Augustin, M, Rybniker, J, Knopp, L, Eggermann, T, Volland, S, Altmueller, J, Berger, MM, Brenner, T, Hinney, A, Witzke, O, Bals, R, Herr, C, Ludwig, N, Walter, J, Fuchsberger, C, Pattaro, C, De Grandi, A, Pramstaller, P, Emmert, D, Melotti, R, Foco, L, Mascalzoni, D, Gogele, M, Domingues, F, Hicks, A, Gignoux, CR, Wicks, SJ, Crooks, K, Barnes, KC, Daya, M, Shortt, J, Rafaels, N, Chavan, S, Goldstein, DB, Kiryluk, K, Sengupta, S, Chung, W, Reilly, MP, Khan, A, Wang, C, Povysil, G, Bhardwaj, N, Gharavi, AG, Ionita-Laza, I, Shang, N, O'Byrne, SM, Nandakumar, R, Menon, A, So, YS, Hod, E, Pendrick, D, Park, S-K, Kim, H-L, Kang, CK, Lee, H-J, Song, K-H, Yoon, KJ, Paik, N-J, Seok, W, Yoon, H, Joo, E-J, Chang, Y, Ryu, S, Park, WB, Park, JS, Park, KU, Ham, SY, Jung, J, Kim, ES, Kim, HB, Ellinghaus, D, Degenhardt, F, Caceres, M, Juzenas, S, Lenz, TL, Albillos, A, Julia, A, Heidecker, B, Garcia, F, Kurth, F, Tran, F, Hanses, F, Zoller, H, Holter, JC, Fernandez, J, Sander, LE, Rosenstiel, P, Koehler, P, de Cid, R, Asselta, R, Schreiber, S, Hehr, U, Prati, D, Baselli, G, Valenti, L, Bujanda, L, Banales, JM, Duga, S, D'Amato, M, Romero-Gomez, M, Buti, M, Invernizzi, P, Franke, A, Hov, JR, Karlsen, TH, Folseraas, T, Maya-Miles, D, Teles, A, Azuure, C, Wacker, EM, Uellendahl-Werth, F, Elabd, H, Arora, J, Lerga-Jaso, J, Wienbrandt, L, Ruehlemann, MC, Wendorff, M, Vadla, MS, Lenning, OB, Oezer, O, Myhre, R, Raychaudhuri, S, Tanck, A, Gassner, C, Hemmrich-Stanisak, G, Kaessens, J, Basso, MEF, Schulzky, M, Wittig, M, Braun, N, Wesse, T, Albrecht, W, Yi, X, Ortiz, AB, Garrido Chercoles, A, Ruiz, A, Mantovani, A, Holten, AR, Mayer, A, Cherubini, A, Protti, A, Aghemo, A, Gerussi, A, Ramirez, A, Braun, A, Barreira, A, Lleo, A, Kildal, AB, Glueck, A, Carreras Nolla, A, Latiano, A, Dyrhol-Riise, AM, Muscatello, A, Voza, A, Rando-Segura, A, Solier, A, Karina, B, Cortes, B, Mateos, B, Nafria-Jimenez, B, Schaefer, B, Bellinghausen, C, Ferrando, C, Quereda, C, Skurk, C, Thibeault, C, Spinner, CD, Lange, C, Hu, C, Cappadona, C, Bianco, C, Sancho, C, Hoff, DAL, Galimberti, D, Jimenez, D, Pestana, D, Toapanta, D, Azzolini, E, Scarpini, E, Helbig, ET, Urrechaga, E, Paraboschi, EM, Pontali, E, Reverter, E, Navas, E, Arana, E, Garcia Sanchez, F, Ceriotti, F, Malvestiti, F, Mesonero, F, Pezzoli, G, Lamorte, G, Neb, H, My, I, Hernandez, I, de Rojas, I, Galvan-Femenia, I, Heyckendorf, J, Badia, JR, Schneider, J, Goikoetxea, J, Kraft, J, Mueller, KE, Gaede, KI, Garcia-Etxebarria, K, Tonby, K, Heggelund, L, Izquierdo-Sanchez, L, Sumoy, L, Lippert, LJ, Terranova, L, Garbarino, L, Tellez, L, Roade, L, Ostadreza, M, Intxausti, M, Kogevinas, M, Gutierrez-Stampa, MA, Vehreschild, MJGT, Marquie, M, Castoldi, M, Cecconi, M, Boada, M, Seilmaier, MJ, Mazzocco, M, Rodriguez-Gandia, M, Imaz Ayo, N, Blay, N, Martinez, N, Cornely, OA, Palmieri, O, Tentorio, P, Rodrigues, PM, Espana, PP, Hoffmann, P, Bacher, P, Suwalski, P, de Pablo, R, Nieto, R, Badalamenti, S, Ciesek, S, Bombace, S, Wilfling, S, Brunak, S, Heilmann-Heimbach, S, Ripke, S, Bahmer, T, Landmesser, U, Protzer, U, Rimoldi, V, Skogen, V, Andrade, V, Moreno, V, Poller, W, Farre, X, Wang, X, Khodamoradi, Y, Karadeniz, Z, de Salazar, A, Palom, A, Garcia-Fernandez, A-E, Blanco-Grau, A, Zanella, A, Bandera, A, Nebel, A, Biondi, A, Caba Llero-Garralda, A, Gori, A, Lind, A, Fracanzani, AL, Peschuck, A, Pesenti, A, De la Horra, C, Milani, C, Paccapelo, C, Angelini, C, Cea, C, Muniz-Diaz, E, Sandoval, E, Calderon, EJ, Solligard, E, Aziz, F, Martinelli-Boneschi, F, Peyvandi, F, Blasi, F, Medrano, FJ, Rodriguez-Frias, F, Mueller, F, Grasselli, G, Costantino, G, Cardamone, G, Foti, G, Matullo, G, Kurihara, H, Afset, JE, Damas, JK, Ampuero, J, Martin, J, Erdmann, J, Bergan, J, Goerg, S, Ferrusquia-Acosta, J, Hernandez Quero, J, Delgado, J, Guerrero, JM, Risnes, K, Bettini, LR, Moreira, L, Gustad, LT, Santoro, L, Scudeller, L, Riveiro-Barciela, M, Schaefer, M, Carrabba, M, Valsecchi, MG, Hernandez-Tejero, M, Acosta-Herrera, M, D'Angio, M, Baldini, M, Cazzaniga, M, Ciccarelli, M, Bocciolone, M, Miozzo, M, Chueca, N, Montano, N, Faverio, P, Preatoni, P, Bonfanti, P, Omodei, P, Castro, P, Ferrer, R, Gualtierotti, R, Gallego-Duran, R, Morilla, R, Haider, S, Marsal, S, Aneli, S, Pelusi, S, Bosari, S, Aliberti, S, Dudman, S, Zheng, T, Pumarola, T, Gonzalez Cejudo, T, Monzani, V, Friaza, V, Peter, W, Dopazo, X, May, S, Grimsrud, MM, Gudbjartsson, DF, Stefansson, K, Sulem, P, Sveinbjornsson, G, Melsted, P, Norddahl, G, Moore, KHS, Thorsteinsdottir, U, Holm, H, Alarcon-Riquelme, ME, Bernardo, D, Martinez-Bueno, M, Rojo Rello, S, Magi, R, Milani, L, Metspalu, A, Laisk, T, Lall, K, Lepamets, M, Esko, T, Reimann, E, Naaber, P, Laane, E, Pesukova, J, Peterson, P, Kisand, K, Tabri, J, Allos, R, Hensen, K, Starkopf, J, Ringmets, I, Tamm, A, Kallaste, A, Alavere, H, Metsalu, K, Puusepp, M, Kristiansson, K, Koskelainen, S, Perola, M, Donner, K, Kivinen, K, Palotie, A, Rivolta, C, Bochud, P-Y, Bibert, S, Boillat, N, Nussle, SG, Albrich, W, Quinodoz, M, Kamdar, D, Suh, N, Neofytos, D, Erard, V, Voide, C, Bochud, PY, Friolet, R, Vollenweider, P, Pagani, JL, Oddo, M, zu Bentrup, FM, Conen, A, Clerc, O, Marchetti, O, Guillet, A, Guyat-Jacques, C, Foucras, S, Rime, M, Chassot, J, Jaquet, M, Viollet, RM, Lannepoudenx, Y, Portopena, L, Desgranges, F, Filippidis, P, Guery, B, Haefliger, D, Kampouri, EE, Manuel, O, Munting, A, Iou-Olivgeris, MP, Regina, J, Rochat-Stettler, L, Suttels, V, Tadini, E, Tschopp, J, Van Singer, M, Viala, B, Boillat-Blanco, N, Brahier, T, Hugli, O, Meuwly, JY, Pantet, O, Bochud, M, D'Acremont, V, Younes, SE, Albrich, WC, Cerny, A, O'Mahony, L, von Mering, C, Frischknecht, M, Kleger, G-R, Filipovic, M, Kahlert, CR, Wozniak, H, Negro, TR, Pugin, J, Bouras, K, Knapp, C, Egger, T, Perret, A, Montillier, P, di Bartolomeo, C, Barda, B, Carreras, A, Mercader, JM, Guindo-Martinez, M, Torrents, D, Garcia-Aymerich, J, Castano-Vinyals, G, Dobano, C, Gori, M, Mondelli, MU, Castelli, F, Vaghi, M, Rusconi, S, Montagnani, F, Bargagli, E, Franchi, F, Mazzei, MA, Cantarini, L, Tacconi, D, Feri, M, Scala, R, Spargi, G, Nencioni, C, Bandini, M, Caldarelli, GP, Spagnesi, M, Canaccini, A, Ognibene, A, Monforte, AD, Girardis, M, Antinori, A, Francisci, D, Schiaroli, E, Scotton, PG, Panese, S, Scaggiante, R, Della Monica, M, Capasso, M, Fiorentino, G, Castori, M, Aucella, F, Di Biagio, A, Masucci, L, Valente, S, Mandala, M, Zucchi, P, Giannattasio, F, Coviello, DA, Mussini, C, Bosio, G, Tavecchia, L, Crotti, L, Rizzi, M, La Rovere, MT, Sarzi-Braga, S, Bussotti, M, Ravaglia, S, Artuso, R, Perrella, A, Romani, D, Bergomi, P, Catena, E, Vincenti, A, Ferri, C, Grassi, D, Pessina, G, Tumbarello, M, Di Pietro, M, Sabrina, R, Luchi, S, Barbieri, C, Acquilini, D, Andreucci, E, Paciosi, F, Segala, FV, Tiseo, G, Falcone, M, Lista, M, Poscente, M, De Vivo, O, Petrocelli, P, Guarnaccia, A, Baroni, S, Perticaroli, V, Furini, S, Dei, S, Benetti, E, Picchiotti, N, Sanarico, M, Pinoli, P, Raimondi, F, Biscarini, F, Stella, A, Bergomi, M, Zguro, K, Capitani, K, Tanfoni, M, Fallerini, C, Daga, S, Baldassarri, M, Fava, F, Frullanti, E, Valentino, F, Doddato, G, Giliberti, A, Tita, R, Amitrano, S, Bruttini, M, Croci, S, Meloni, I, Mencarelli, MA, Lo Rizzo, C, Pinto, AM, Beligni, G, Tommasi, A, Di Sarno, L, Palmieri, M, Carriero, ML, Alaverdian, D, Iuso, N, Inchingolo, G, Busani, S, Bruno, R, Vecchia, M, Belli, MA, Mantovani, S, Ludovisi, S, Quiros-Roldan, E, Antoni, MD, Zanella, I, Siano, M, Emiliozzi, A, Fabbiani, M, Rossetti, B, Zanelli, G, Bergantini, L, D'Alessandro, M, Cameli, P, Bennet, D, Anedda, F, Marcantonio, S, Scolletta, S, Guerrini, S, Conticini, E, Frediani, B, Spertilli, C, Donati, A, Guidelli, L, Corridi, M, Croci, L, Piacentini, P, Desanctis, E, Cappelli, S, Verzuri, A, Anemoli, V, Pancrazi, A, Lorubbio, M, Merlini, E, Miraglia, FG, Venturelli, S, Cossarizza, A, Vergori, A, Gabrieli, A, Riva, A, Andretta, F, Gatti, F, Parisi, SG, Baratti, S, Piscopo, C, Russo, R, Andolfo, I, Iolascon, A, Carella, M, Merla, G, Squeo, GM, Raggi, P, Marciano, C, Perna, R, Bassetti, M, Sanguinetti, M, Giorli, A, Salerni, L, Parravicini, P, Menatti, E, Trotta, T, Coiro, G, Lena, F, Martinelli, E, Mancarella, S, Gabbi, C, Maggiolo, F, Ripamonti, D, Bachetti, T, Suardi, C, Parati, G, Botta, G, Di Domenico, P, Rancan, I, Bianchi, F, Colombo, R, van Heel, DA, Hunt, KA, Trembath, RC, Huang, QQ, Martin, HC, Mason, D, Trivedi, B, Wright, J, Finer, S, Griffiths, CJ, Akhtar, S, Anwar, M, Arciero, E, Ashraf, S, Breen, G, Chung, R, Curtis, CJ, Chowdhury, M, Colligan, G, Deloukas, P, Durham, C, Griffiths, C, Hurles, M, Hussain, S, Islam, K, Lavery, C, Lee, SH, Lerner, R, MacArthur, D, MacLaughlin, B, Martin, H, Miah, S, Newman, B, Safa, N, Tahmasebi, F, Smith, AV, Boughton, AP, Li, KW, LeFaive, J, Annis, A, Jannes, CE, Krieger, JE, Pereira, AC, Velho, M, Marques, E, Lima, IR, Tada, MT, Valino, K, McCarthy, M, Rosenberger, C, Lee, JE, Chang, D, Hammer, C, Hunkapiller, J, Mahajan, A, Pendergrass, S, Sucheston-Campbell, L, Yaspan, B, Lee, HS, Shin, E, Jang, HY, Kym, S, Kim, Y-S, Jeong, H, Kwon, KT, Kim, S-W, Kim, JY, Jang, YR, Kim, HA, Lee, JY, Choe, K-W, Kang, YM, Jee, SH, Jung, KJ, Parikh, V, Ashley, E, Wheeler, M, Rivas, M, Bustamante, C, Pinksy, B, Febbo, P, Farh, K, Schroth, GP, deSouza, F, Dalton, K, Christle, J, Deboever, C, Szalma, S, Rubinacci, S, Delaneau, O, Gorzynski, J, de Jong, H, Sutton, S, Youlton, N, Joshi, R, Jimenez-Morales, D, Hughes, C, Amar, D, Ioannidis, A, Hershman, S, Kirillova, A, Seo, K, Huang, Y, Shoura, M, Hammond, N, Watson, N, Raja, A, Huang, C, Sahoo, M, Wang, H, Zhen, J, Rakitko, A, Ilinsky, V, Yermakovich, D, Popov, I, Chernitsov, A, Kovalenko, E, Krasnenko, A, Plotnikov, N, Stetsenko, I, Kim, A, Cirulli, ET, Barrett, KMS, Bolze, A, White, S, Washington, NL, Lu, JT, Riffle, S, Tanudjaja, F, III, RJM, Leonetti, N, Neveux, I, Dabe, S, Grzymski, JJ, Minano, JIE, Aguirre, LA, Lopez-Collazo, E, Pazos, MDLM, Cerrato, L, Lozano-Rodriguez, R, Avendano-Ortiz, J, Terron Arcos, V, Marina Montalban-Hernandez, K, Valentin Quiroga, J, Pascual-Iglesias, A, Maroun-Eid, C, Martin-Quiros, A, Namkoong, H, Imoto, S, Katayama, K, Fukunaga, K, Kitagawa, Y, Sato, T, Hasegawa, N, Kumanogoh, A, Kimura, A, Ai, M, Tokunaga, K, Kanai, T, Miyano, S, Ogawa, S, Edahiro, R, Sonehara, K, Shirai, Y, Ishii, M, Kabata, H, Masaki, K, Kamata, H, Ikemura, S, Chubachi, S, Okamori, S, Terai, H, Tanaka, H, Morita, A, Lee, H, Asakura, T, Sasaki, J, Morisaki, H, Uwamino, Y, Nanki, K, Mikami, Y, Tomono, K, Kato, K, Matsuda, F, Takahashi, M, Hizawa, N, Takeda, Y, Hirata, H, Shiroyama, T, Miyawaki, S, Suzuki, K, Maeda, Y, Nii, T, Noda, Y, Niitsu, T, Adachi, Y, Enomoto, T, Amiya, S, Hara, R, Takahashi, K, Anzai, T, Hasegawa, T, Ito, S, Koike, R, Endo, A, Uchimura, Y, Miyazaki, Y, Honda, T, Tateishi, T, Tohda, S, Ichimura, N, Sonobe, K, Sassa, C, Nakajima, J, Nannya, Y, Omae, Y, Harada, N, Hiki, M, Takagi, H, Nakamura, A, Tagaya, E, Kawana, M, Arimura, K, Ishiguro, T, Takayanagi, N, Isono, T, Takaku, Y, Takano, K, Anan, R, Nakajima, Y, Nakano, Y, Nishio, K, Ueda, S, Hayashi, R, Tateno, H, Hase, I, Yoshida, S, Suzuki, S, Mitamura, K, Saito, F, Ueda, T, Azuma, M, Nagasaki, T, Yasui, Y, Hasegawa, Y, Mutoh, Y, Yoshiyama, T, Shoko, T, Kojima, M, Adachi, T, Ishikawa, M, Watanabe, K, Manabe, T, Ito, F, Fukui, T, Funatsu, Y, Koh, H, Hirai, Y, Kawashima, H, Narita, A, Niwa, K, Sekikawa, Y, Yoshiya, K, Yoshihara, T, Suzuki, Y, Nakayama, S, Masuzawa, K, Nishi, K, Nishitsuji, M, Tani, M, Inoue, T, Hirano, T, Kobayashi, K, Miyazawa, N, Kimura, Y, Sado, R, Ogura, T, Kitamura, H, Murohashi, K, Nakachi, I, Baba, R, Arai, D, Fuke, S, Saito, H, Kuwahara, N, Fujiwara, A, Okada, T, Baba, T, Noda, J, Mashimo, S, Yagi, K, Shiomi, T, Hashiguchi, M, Odani, T, Mochimaru, T, Oyamada, Y, Mori, N, Izumi, N, Nagata, K, Taki, R, Murakami, K, Yamada, M, Sugiura, H, Hayashi, K, Shimizu, T, Gon, Y, Fujitani, S, Tsuchida, T, Yoshida, T, Kagaya, T, Kita, T, Sakagami, S, Kimizuka, Y, Kawana, A, Nakamura, Y, Ishikura, H, Takata, T, Kikuchi, T, Taniyama, D, Nakamura, M, Kodama, N, Kaneyama, Y, Maeda, S, Nagasaki, Y, Okamoto, M, Ishihara, S, Ito, A, Chihara, Y, Takeuchi, M, Onoi, K, Hashimoto, N, Wakahara, K, Ando, A, Masuda, M, Wakabayashi, A, Watanabe, H, Sageshima, H, Nakada, T-A, Abe, R, Shimada, T, Kawamura, K, Ichikado, K, Nishiyama, K, Yamasaki, M, Hashimoto, S, Kusaka, Y, Ohba, T, Isogai, S, Takada, M, Kanda, H, Komase, Y, Sano, F, Asano, K, Oguma, T, Harada, M, Takahashi, T, Shibusawa, T, Abe, S, Kono, Y, Togashi, Y, Izumo, T, Inomata, M, Awano, N, Ogata, T, Kanehiro, A, Ozaki, S, Fuchimoto, Y, Ogura, S, Yoshida, K, Beppu, S, Fukuyama, S, Eriguchi, Y, Yonekawa, A, Inoue, Y, Yamagata, K, Chiba, S, Narumoto, O, Nagai, H, Ooshima, N, Motegi, M, Sagara, H, Tanaka, A, Ohta, S, Shibata, Y, Tanino, Y, Sato, Y, Yamada, Y, Hashino, T, Shinoki, M, Iwagoe, H, Imamura, T, Umeda, A, Shimada, H, Endo, M, Hayashi, S, Nakano, S, Yatomi, M, Maeno, T, Ishii, T, Utsugi, M, Ono, A, Kanaoka, K, Ihara, S, Komuta, K, Boezen, M, Claringbould, A, Lopera, E, Warmerdam, R, Vonk, JM, van Blokland, I, Lanting, P, Ori, APS, Obeidat, M, Cordero, AIH, Sin, DD, Bosse, Y, Joubert, P, Hao, K, Nickle, D, Timens, W, van den Berge, M, Feng, Y-CA, Mercader, J, Weiss, ST, Karlson, EW, Smoller, JW, Murphy, SN, Meigs, JB, Woolley, AE, Green, RC, Perez, EF, Zollner, S, Wang, J, Beck, A, Sloofman, LG, Ascolillo, S, Sebra, RP, Collins, BL, Levy, T, Sealfon, SC, Jordan, DM, Thompson, RC, Gettler, K, Chaudhary, K, Belbin, GM, Preuss, M, Hoggart, C, Choi, S, Underwood, SJ, Salib, I, Britvan, B, Keller, K, Tang, L, Peruggia, M, Hiester, LL, Niblo, K, Aksentijevich, A, Labkowsky, A, Karp, A, Zlatopolsky, M, Zyndorf, M, Charney, AW, Beckmann, ND, Schadt, EE, Abul-Husn, NS, Cho, JH, Itan, Y, Kenny, EE, Loos, RJF, Nadkarni, GN, Do, R, O'Reilly, P, Huckins, LM, Ferreira, MAR, Abecasis, GR, Leader, JB, Cantor, MN, Justice, AE, Carey, DJ, Chittoor, G, Josyula, NS, Kosmicki, JA, Horowitz, JE, Baras, A, Gass, MC, Yadav, A, Mirshahi, T, Hottenga, JJ, Bartels, M, de Geus, EJC, Nivard, MG, Verma, A, Ritchie, MD, Rader, D, Li, B, Verma, SS, Lucas, A, Bradford, Y, Zara, F, Salpietro, V, Scala, M, Iacomino, M, Scudieri, P, Bocciardi, R, Minetti, C, Vari, MS, Rahier, J-F, Giorgio, E, Carli, D, Louis, E, Bulik, CM, Landen, M, Brusco, A, Ferrero, GB, Madia, F, Fundin, B, Ismail, SI, Saad, C, Al-Sarraj, Y, Badji, RM, Al-Muftah, W, Al Thani, A, Afifi, N, Klovins, J, Rovite, V, Rescenko, R, Peculis, R, Ustinova, M, Zeberg, H, Frithiof, R, Hultstrom, M, Lipcsey, M, Johnson, R, Geschwind, DH, Freimer, N, Butte, MJ, Ding, Y, Chiu, A, Chang, TS, Boutros, P, Moutsianas, L, Caulfield, MJ, Scott, RH, Walker, S, Stuckey, A, Odhams, CA, Rhodes, D, Fowler, T, Rendon, A, Chan, G, Arumugam, P, Karczewski, KJ, Wilson, DJ, Spencer, CA, Crook, DW, Wyllie, DH, O'Connell, AM, Atkinson, EG, Tsuo, K, Baya, N, Turley, P, Gupta, R, Walters, RK, Palmer, DS, Sarma, G, Cheng, N, Lu, W, Churchhouse, C, Goldstein, JI, King, D, Seed, C, Daly, MJ, Bryant, S, Satterstrom, FK, Band, G, Earle, SG, Lin, S-K, Arning, N, Armstrong, J, Rudkin, JK, Callier, S, Cusick, C, Soranzo, N, Zhao, JH, Danesh, J, Di Angelantonio, E, Butterworth, AS, Sun, YV, Huffman, JE, Cho, K, O'Donnell, CJ, Tsao, P, Gaziano, JM, Peloso, G, Ho, Y-L, Mian, M, Scaggiante, F, Chang, X, Glessner, JR, Hakonarson, H, Baillie, JK, McGuigan, PJ, Moore, LSP, Vizcaychipi, MP, Hall, K, Campbell, A, Nichol, A, Ward, G, Page, VJ, Semple, MG, Adeniji, K, Agranoff, D, Agwuh, K, Ail, D, Aldera, EL, Alegria, A, Angus, B, Ashish, A, Atkinson, D, Bari, S, Barlow, G, Barnass, S, Barrett, N, Bassford, C, Basude, S, Baxter, D, Beadsworth, M, Bernatoniene, J, Berridge, J, Best, N, Bothma, P, Chadwick, D, Brittain-Long, R, Bulteel, N, Burden, T, Burtenshaw, A, Caruth, V, Chambler, D, Chee, N, Child, J, Chukkambotla, S, Clark, T, Collini, P, Cosgrove, C, Cupitt, J, Cutino-Moguel, M-T, Dark, P, Dawson, C, Dervisevic, S, Donnison, P, Douthwaite, S, Drummond, A, DuRand, I, Dushianthan, A, Dyer, T, Evans, C, Eziefula, C, Fegan, C, Finn, A, Fullerton, D, Garg, S, Garg, A, Gkrania-Klotsas, E, Godden, J, Goldsmith, A, Graham, C, Hardy, E, Hartshorn, S, Harvey, D, Havalda, P, Hawcutt, DB, Hobrok, M, Hodgson, L, Hormis, A, Jacobs, M, Jain, S, Jennings, P, Kaliappan, A, Kasipandian, V, Kegg, S, Kelsey, M, Kendall, J, Kerrison, C, Kerslake, I, Koch, O, Koduri, G, Koshy, G, Laha, S, Laird, S, Larkin, S, Leiner, T, Lillie, P, Limb, J, Linnett, V, Little, J, Lyttle, M, MacMahon, M, MacNaughton, E, Mankregod, R, Masson, H, Matovu, E, McCullough, K, McEwen, R, Meda, M, Mills, GH, Minton, J, Ward, K, Mirfenderesky, M, Mohandas, K, Mok, Q, Moon, J, Moore, E, Morgan, P, Morris, C, Mortimore, K, Moses, S, Mpenge, M, Mulla, R, Murphy, M, Nagel, M, Nagarajan, T, Nelson, M, O'Shea, MK, Otahal, I, Ostermann, M, Pais, M, Panchatsharam, S, Papakonstantinou, D, Paraiso, H, Patel, B, Pattison, N, Pepperell, J, Peters, M, Phull, M, Pintus, S, Pooni, JS, Post, F, Price, D, Prout, R, Rae, N, Reschreiter, H, Reynolds, T, Richardson, N, Roberts, M, Roberts, D, Rose, A, Rousseau, G, Ryan, B, Saluja, T, Shah, A, Shanmuga, P, Sharma, A, Shawcross, A, Sizer, J, Shankar-Hari, M, Smith, R, Snelson, C, Spittle, N, Staines, N, Stambach, T, Stewart, R, Subudhi, P, Szakmany, T, Tatham, K, Thomas, J, Thompson, C, Thompson, R, Tridente, A, Tupper-Carey, D, Twagira, M, Ustianowski, A, Vallotton, N, Vincent-Smith, L, Visuvanathan, S, Vuylsteke, A, Waddy, S, Wake, R, Walden, A, Welters, I, Whitehouse, T, Whittaker, P, Whittington, A, Papineni, P, Wijesinghe, M, Williams, M, Wilson, L, Cole, S, Winchester, S, Wiselka, M, Wolverson, A, Wooton, DG, Workman, A, Yates, B, Young, P, Beale, R, Bretherick, AD, Clohisey, S, Fourman, MH, Furniss, J, Gountouna, E, Grimes, G, Haley, C, Harrison, D, Hayward, C, Keating, S, Klaric, L, Klenerman, P, Law, A, Meynert, AM, Millar, J, Pairo-Castineira, E, Parkinson, N, Ponting, CP, Porteous, DJ, Rawlik, K, Richmond, A, Rowan, K, Russell, CD, Shen, X, Shih, B, Tenesa, A, Vitart, V, Wang, B, Wilson, JF, Wu, Y, Yang, J, Yang, Z, Zechner, M, Zhai, R, Zheng, C, Norman, L, Pius, R, Drake, TM, Fairfield, CJ, Knight, SR, Mclean, KA, Murphy, D, Shaw, CA, Dalton, J, Girvan, M, Saviciute, E, Roberts, S, Harrison, J, Marsh, L, Connor, M, Halpin, S, Jackson, C, Gamble, C, Leeming, G, Wham, M, Hendry, R, Scott-Brown, J, Begg, C, Hinds, C, Ho, AYW, Horby, PW, Knight, J, Ling, L, Maslove, D, McAuley, D, Montgomery, H, Openshaw, PJM, Summers, C, Walsh, T, Armstrong, L, Bates, H, Dooks, E, Farquhar, F, Hairsine, B, McParland, C, Packham, S, Alldis, Z, Lain, RA-C, Bibi, F, Biddle, J, Blow, S, Bolton, M, Borra, C, Bowles, R, Burton, M, Choudhury, Y, Collier, D, Cox, A, Easthope, A, Ebano, P, Fotiadis, S, Gurasashvili, J, Halls, R, Hartridge, P, Kallon, D, Kassam, J, Lancoma-Malcolm, I, Matharu, M, May, P, Mitchelmore, O, Newman, T, Patel, M, Pheby, J, Pinzuti, I, Prime, Z, Prysyazhna, O, Shiel, J, Taylor, M, Tierney, C, Wood, S, Zak, A, Zongo, O, Forsey, M, Nicholson, A, Riches, J, Vertue, M, Wasson, C, Finn, S, Green, J, Collins, E, King, B, Grauslyte, L, Hussain, M, Pogreban, T, Rosaroso, L, Salciute, E, Franke, G, Wong, J, George, A, Akeroyd, L, Bano, S, Bromley, M, Gurr, L, Lawton, T, Morgan, J, Sellick, K, Warren, D, Wilkinson, B, McGowan, J, Ledgard, C, Stacey, A, Pye, K, Bellwood, R, Bentley, M, Loosley, R, McGuinness, H, Tench, H, Wolf-Roberts, R, Gibson, S, Lyle, A, McNeela, F, Radhakrishnan, J, Hughes, A, Ali, A, Brady, M, Dale, S, Dance, A, Gledhill, L, Greig, J, Hanson, K, Holdroyd, K, Home, M, Kelly, D, Kitson, R, Matapure, L, Melia, D, Mellor, S, Nortcliffe, T, Pinnell, J, Robinson, M, Shaw, L, Shaw, R, Thomis, L, Wilson, A, Wood, T, Bayo, L-A, Merwaha, E, Ishaq, T, Hanley, S, Antcliffe, D, Banach, D, Brett, S, Coghlan, P, Fernandez, Z, Gordon, A, Rojo, R, Arias, SS, Templeton, M, Jha, R, Krishnamurthy, V, Lim, L, Bi, R, Scholefield, B, Ashton, L, Williams, A, Cheyne, C, Saunderson, A, Allan, A, Anderson, F, Kaye, C, Liew, J, Medhora, J, Scott, T, Trumper, E, Botello, A, Polgarova, P, Stroud, K, Meaney, E, Jones, M, Ng, A, Agrawal, S, Pathan, N, White, D, Daubney, E, Elston, K, Parker, R, Reddy, A, Turner-Bone, I, Wilding, L, Harding, P, Jacob, R, Jones, C, Denmade, C, Croft, M, White, I, Griffin, D, Muchenje, N, Mupudzi, M, Partridge, R, Conyngham, J-A, Thomas, R, Wright, M, Corral, MA, Bastion, V, Clarke, D, David, B, Kent, H, Lorusso, R, Lubimbi, G, Murdoch, S, Penacerrada, M, Thomas, A, Valentine, J, Vochin, A, Wulandari, R, Djeugam, B, Dawson, J, Garrioch, S, Tolson, M, Aldridge, J, Martins, LGDA, Carungcong, J, Beavis, S, Dale, K, Gascoyne, R, Hawes, J, Pritchard, K, Stevenson, L, Whileman, A, Cowley, A, Highgate, J, Crawley, R, Crew, A, Cunningham, M, Daniels, A, Harrison, L, Hope, S, Inweregbu, K, Jones, S, Lancaster, N, Matthews, J, Wray, G, Benham, L, Bradshaw, Z, Brown, J, Caswell, M, Melling, S, Preston, S, Slawson, N, Stoddard, E, Warden, S, Combes, E, Joefield, T, Monnery, S, Beech, V, Trotman, S, Hopkins, B, Scriven, J, Thrasyvoulou, L, Willis, H, Anderson, S, Birch, J, Hammerton, K, O'Leary, R, Abernathy, C, Foster, L, Gratrix, A, Martinson, V, Parkinson, P, Stones, E, Carbral-Ortega, L, Kapoor, R, Loader, D, Castle, K, Brandwood, C, Smith, L, Clark, R, Birchall, K, Kolakaluri, L, Baines, D, Sukumaran, A, Mapfunde, I, Meredith, M, Morris, L, Ryan, L, Clark, A, Sampson, J, Peters, C, Dent, M, Langley, M, Wei, S, Andrew, A, Chablani, M, Kirkby, A, Netherton, K, Bates, M, Dasgin, J, Gill, J, Nilsson, A, Apetri, E, Basikolo, C, Blackledge, B, Catlow, L, Charles, B, Doonan, R, Harris, J, Harvey, A, Horner, D, Knowles, K, Lomas, D, Lyons, C, Marsden, T, McLaughlan, D, McMorrow, L, Pendlebury, J, Perez, J, Poulaka, M, Proudfoot, N, Slaughter, M, Slevin, K, Thomas, V, Walker, D, Michael, A, Collis, M, Clark, M, Coulding, M, Jude, E, McCormick, J, Mercer, O, Potla, D, Rehman, H, Savill, H, Turner, V, Davey, M, Golden, D, Seaman, R, Hunt, J, Dearden, J, Dobson, E, Mulcahy, M, Munt, S, O'Connor, G, Philbin, J, Rishton, C, Tully, R, Winnard, S, Cagova, L, Fofano, A, Garner, L, Holcombe, H, Mepham, S, Mitchell, AM, Mwaura, L, Praman, K, Zamikula, J, Bercades, G, Brealey, D, Hass, I, MacCallum, N, Martir, G, Raith, E, Reyes, A, Smyth, D, Taylor, A, Hughes, RA, Thomas, H, Rees, A, Duskova, M, Phipps, J, Brooks, S, Edwards, M, Alexander, P, Allen, S, Bradley-Potts, J, Brantwood, C, Egan, J, Felton, T, Padden, G, Ward, L, Moss, S, Glasgow, S, Beesley, K, Board, S, Kubisz-Pudelko, A, Lewis, A, Perry, J, Pippard, L, Wood, D, Buckley, C, Brown, A, Gregory, J, O'Connell, S, Smith, T, Belagodu, Z, Fuller, B, Gherman, A, Olufuwa, O, Paramsothy, R, Stuart, C, Oakley, N, Kamundi, C, Tyl, D, Collins, K, Silva, P, Taylor, J, King, L, Coates, C, Crowley, M, Wakefield, P, Beadle, J, Johnson, L, Sargeant, J, Anderson, M, Jardine, C, Williams, D, Parris, V, Quaid, S, Watson, E, Melville, J, Naisbitt, J, Joseph, R, Lazo, M, Walton, O, Neal, A, Hill, M, Kannan, T, Wild, L, Allan, E, Darlington, K, Davies, F, Easton, J, Kumar, S, Lean, R, Menzies, D, Pugh, R, Qiu, X, Davies, L, Williams, H, Scanlon, J, Davies, G, Mackay, C, Lewis, J, Rees, S, Coetzee, S, Gales, A, Raj, M, Sell, C, Langton, H, Watters, M, Novis, C, Arbane, G, Bociek, A, Campos, S, Grau, N, Jones, TO, Lim, R, Marotti, M, Whitton, C, Barron, A, Collins, C, Kaul, S, Passmore, H, Prendergast, C, Reed, A, Rogers, P, Shokkar, R, Woodruff, M, Middleton, H, Polgar, O, Nolan, C, Thwaites, V, Mahay, K, Sri-Chandana, C, Scherewode, J, Stephenson, L, Marsh, S, Bancroft, H, Bellamy, M, Carmody, M, Daglish, J, Moore, F, Rhodes, J, Sangombe, M, Kadiri, S, Ayers, A, Harrison, W, North, J, Cavazza, A, Cockrell, M, Corcoran, E, Depante, M, Finney, C, Jerome, E, McPhail, M, Nayak, M, Noble, H, O'Reilly, K, Pappa, E, Saha, R, Saha, S, Smith, J, Knighton, A, Gill, M, Paul, P, Ratnam, V, Shelton, S, Wynter, I, Baptista, D, Crowe, R, Fernandes, R, Herdman-Grant, R, Joseph, A, Loveridge, A, McKenley, I, Morino, E, Naranjo, A, Simms, R, Sollesta, K, Swain, A, Venkatesh, H, Khera, J, Fox, J, Barber, R, Hewitt, C, Hilldrith, A, Jackson-Lawrence, K, Shepardson, S, Wills, M, Butler, S, Tavares, S, Cunningham, A, Hindale, J, Arif, S, George, L, Twiss, S, Wright, D, Holland, M, Keenan, N, Lyons, M, Wassall, H, Marsh, C, Mahenthran, M, Carter, E, Kong, T, Adanini, O, Bhatia, N, Msiska, M, Mew, L, Mwaura, E, Williams, F, Wren, L, Sutherland, S-B, Battle, C, Brinkworth, E, Harford, R, Murphy, C, Newey, L, Rees, T, Arnold, S, Hardy, J, Houlden, H, Moncur, E, Tariq, A, Tucci, A, Convery, K, Fottrell-Gould, D, Hudig, L, Keshet-Price, J, Randell, G, Stammers, K, Abdelrazik, M, Bakthavatsalam, D, Elhassan, M, Ganesan, A, Haldeos, A, Moreno-Cuesta, J, Purohit, D, Vincent, R, Xavier, K, Rohit, K, Alasdair, F, Saleem, M, David, C, Jenkins, S, Lamond, Z, Wall, A, Reynolds, J, Campbell, H, Thompsom, M, Dodds, S, Duffy, S, Butcher, D, O'Sullivan, S, Butterworth-Cowin, N, Deacon, B, Hibbert, M, Pothecary, C, Tetla, D, Woodford, C, Durga, L, Kennard-Holden, G, de Gordoa, LO-R, Peasgood, E, Phillips, C, Skinner, D, Gaylard, J, Mullan, D, Newman, J, Davies, E, Roche, L, Sathe, S, Brimfield, L, Daly, Z, Pogson, D, Rose, S, Collins, A, Khaliq, W, Gude, ET, Allen, L, Beranova, E, Crisp, N, Deery, J, Hazelton, T, Knight, A, Price, C, Tilbey, S, Turki, S, Turney, S, Giles, J, Booth, S, Bell, G, English, K, Katary, A, Wilcox, L, Campbell, R, Clarke, N, Whiteside, J, Mascarenhas, M, Donaldson, A, Matheson, J, Barrett, F, O'Hara, M, O'Keefe, L, Bradley, C, Walker, R, Maynard, V, Patel, T, Smith, M, Kazi, A, Hartley, J, Dykes, J, Hijazi, M, Keith, S, Khan, M, Ryan-Smith, J, Springle, P, Truman, N, Saad, S, Coleman, D, Fine, C, Matt, R, Gay, B, Dalziel, J, Ali, S, Goodchild, D, Harling, R, Bhatterjee, R, Goddard, W, Davison, C, Duberly, S, Hargreaves, J, Bolton, R, Verlander, M, Blackman, H, Creagh-Brown, B, Donlon, S, Michalak-Glinska, N, Mtuwa, S, Pristopan, V, Salberg, A, Smith, E, Stone, S, Piercy, C, Verula, J, Burda, D, Montaser, R, Harden, L, Mayangao, I, Marriott, C, Bradley, P, Harris, C, Cooper, J, Finch, C, Liderth, S, Quinn, A, Waddington, N, Fidler, K, Tagliavini, E, Donnelly, K, Abel, L, Brett, M, Digby, B, Gemmell, L, Hornsby, J, MacGoey, P, O'Neil, P, Price, R, Rodden, N, Rooney, K, Sundaram, R, Thomson, N, Flanagan, R, Hughes, G, Latham, S, McKenna, E, Anderson, J, Hull, R, Rhead, K, Branney, D, Frankham, J, Pitts, S, White, N, Cristiano, D, Dormand, N, Farzad, Z, Gummadi, M, Liyanage, K, Patel, BV, Salmi, S, Sloane, G, Varghese, M, Zborowski, AC, Bean, S, Burt, K, Spivey, M, Eastgate-Jackson, C, Filipe, H, Martin, D, Maharajh, A, Garcia, SM, De Neef, M, Lynch, C, Howe, GS, Singh, J, Turner, K, Ellis, H, Stroud, N, Cherian, S, Cutler, S, Heron, AE, Roynon-Reed, A, Williams, G, Richards, O, Cheema, Y, Ahmad, N, Barker, J, Bauchmuller, K, Bird, S, Cawthron, K, Harrington, K, Jackson, Y, Kibutu, F, Lenagh, B, Masuko, S, Raithatha, A, Wiles, M, Willson, J, Newell, H, Lye, A, Nwafor, L, Jarman, C, Rowland-Jones, S, Foote, D, Cole, J, Watson, J, Hesseldon, L, Macharia, I, Chetam, L, Ford, A, Housley, K, Milner, L, Hanratty, H, Trower, H, Phillips, P, Oxspring, S, Donne, B, Bevan, E, Trodd, D, Watson, G, Brown, CW, Bunni, L, Jennings, C, Latif, M, Marshall, R, Subramanian, G, Bandla, N, Gellamucho, M, Davies, M, Trim, F, Eapen, B, Ahmed, C, Baines, B, Clamp, S, Colley, J, Haq, R, Hayes, A, Hulme, J, Joseph, S, Kumar, R, Maqsood, Z, Purewal, M, Chandler, B, Elliott, K, Mallinson, J, Turnbull, A, Dent, K, Horsley, E, Akhtar, MN, Pearson, S, Potoczna, D, Spencer, S, Blakemore, H, Borislavova, B, Faulkner, B, Gendall, E, Goff, E, Hayes, K, Thomas, M, Worner, R, Smith, K, Stephens, D, Delgado, CC, Dawson, D, Ding, L, Durrant, G, Ezeobu, O, Farnell-Ward, S, Harrison, A, Kanu, R, Leaver, S, Maccacari, E, Manna, S, Saluzzio, RP, Queiroz, J, Samakomva, T, Sicat, C, Texeira, J, Da Gloria, EF, Lisboa, A, Rawlins, J, Mathew, J, Kinch, A, Hurt, WJ, Shah, N, Clark, V, Thanasi, M, Yun, N, Patel, K, Crickmore, V, Debreceni, G, Wilkins, J, Nicol, L, Burn, I, Hambrook, G, Manso, K, Penn, R, Shanmugasundaram, P, Tebbutt, J, Thornton, D, Rostron, A, Roy, A, Woods, L, Cornell, S, Wakinshaw, F, Rogerson, K, Jarmain, J, Anderson, P, Archer, K, Austin, K, Davis, C, Durie, A, Kelsall, O, Thrush, J, Vigurs, C, Wood, H-L, Tranter, H, Cowley, N, McAlindon, M, Digby, S, Low, E, Morgan, A, Cother, N, Rankin, T, Clayton, S, McCurdy, A, Allibone, S, Mary-Genetu, R, Patel, A, Mac, A, Murphy, A, Mahjoob, P, Nazari, R, Worsley, L, Fagan, A, Ali, IMA, Beaumont, K, Blunt, M, Coton, Z, Curgenven, H, Elsaadany, M, Fernandes, K, Ally, SM, Rangarajan, H, Sarathy, V, Selvanayagam, S, Vedage, D, White, M, Fernandez-Roman, J, Hamilton, DO, Johnson, E, Johnston, B, Martinez, ML, Mulla, S, Shaw, D, Waite, AAC, Waugh, V, Welters, ID, Williams, K, Bemand, T, Black, E, Dela Rosa, A, Howle, R, Jhanji, S, Baikady, RR, Tatham, KC, Thomas, B, Halkes, M, Mercer, P, Thornton, L, West, J, Baird, T, Ruddy, J, Reece-Anthony, R, Birt, M, Cowton, A, Kay, A, Kent, M, Potts, K, Wilkinson, A, Naylor, S, Brown, E, Purvis, S, Davies, R, Duffin, D, Hill, H, Player, B, Thomas, E, Beith, CM, Black, K, Clements, S, Morrison, A, Strachan, D, Clarkson, M, D'Sylva, S, Norman, K, Coventry, T, Fowler, S, McGregor, A, Brady, A, Chan, R, McIvor, S, Prady, H, Whittle, H, Mathew, B, Clapham, M, Harper, R, Poultney, U, Rice, P, Mutch, R, Baird, Y, Butler, A, Chadbourn, I, Folkes, L, Fox, H, Gardner, A, Gomez, R, Hobden, G, King, K, Margarson, M, Martindale, T, Meadows, E, Raynard, D, Thirlwall, Y, Helm, D, Margalef, J, Greer, S, Shuker, K, Smuts, S, Duffield, J, Smith, O, Mallon, L, Claire, W, Birkinshaw, I, Carter, J, Howard, K, Ingham, J, Joy, R, Pearson, H, Roche, S, Scott, Z, Knights, E, Price, A, Thorpe, C, Abraheem, A, Bamford, P, Cawley, K, Dunmore, C, Faulkner, M, Girach, R, Jeffrey, H, Jones, R, London, E, Nagra, I, Nasir, F, Sainsbury, H, Smedley, C, Khade, R, Sundar, A, Tsinaslanidis, G, Behan, T, Burnett, C, Hatton, J, Heeney, E, Mitra, A, Newton, M, Pollard, R, Stead, R, Bough, L, Goodsell, J, Tutton, R, Williams, P, Williams, S, Winter-Goodwin, B, Auld, F, Donnachie, J, Edmond, I, Prentice, L, Runciman, N, Salutous, D, Symon, L, Todd, A, Turner, P, Short, A, Sweeney, L, Murdoch, E, Senaratne, D, Burns, K, Higham, A, Anderson, T, Hawcutt, D, O'Malley, L, Rad, L, Rogers, N, Saunderson, P, Allison, KS, Afolabi, D, Whitbread, J, Jones, D, Dore, R, Lankester, L, Nikitas, N, Wells, C, Stowe, B, Spencer, K, Cathcart, S, Duffy, K, Puxty, A, Puxty, K, Turner, L, Ireland, J, Semple, G, Barry, P, Hilltout, P, Evitts, J, Tyler, A, Waldron, J, Irvine, V, Shelley, B, Akinkugbe, O, Bamford, A, Beech, E, Belfield, H, Bell, M, Davies, C, Jones, GAL, McHugh, T, Meghari, H, O'Neill, L, Peters, MJ, Ray, S, Tomas, AL, Gorman, C, Gupta, A, Timlick, E, Brady, R, Bonner, S, Hugill, K, Jones, J, Liggett, S, Bashyal, A, Davidson, N, Hutton, P, McKechnie, S, Wilson, J, Flint, N, Rekha, P, Hales, D, Cruz, C, Gopal, S, Harris, N, Lake, V, Metherell, S, Radford, E, Clement, I, Gulati, A, Hays, C, Webster, K, Hudson, A, Webster, A, Stephenson, E, McCormack, L, Slater, V, Nixon, R, Hanson, H, Fearby, M, Kelly, S, Bridgett, V, Robinson, P, Almaden-Boyle, C, Austin, P, Cabrelli, L, Casey, M, Chapman, S, Whyte, C, Brayne, A, Fisher, E, Jackson, P, Kaye, D, Love, N, Parkin, J, Tuckey, V, van Koutrik, L, Carter, S, Andrew, B, Findlay, L, Adams, K, Bruce, M, Connolly, K, Duncan, T, Michael, HT, Lindergard, G, Hey, S, Fox, C, Alfonso, J, Durrans, LJ, Guerin, J, Hruska, M, Eltayeb, A, Lamb, T, Hodgkiss, T, Cooper, L, Rothwell, J, Dennis, C, Srikaran, S, Sukha, A, Davies, K, O'Brien, L, Omar, Z, Perkins, E, Lewis, T, Sutherland, I, Brooke, H, Buckley, S, Suarez, JC, Charlesworth, R, Hansson, K, Norris, J, Poole, A, Sandhu, R, Sloan, B, Smithson, E, Thirumaran, M, Wagstaff, V, Metcalfe, A, Camsooksai, J, Humphrey, C, Wadams, B, Death, Y, Adams, C, Agasou, A, Arden, T, Bowes, A, Boyle, P, Beekes, M, Button, H, Capps, N, Carnahan, M, Carter, A, Childs, D, Donaldson, D, Hard, K, Hurford, F, Hussain, Y, Javaid, A, Jose, S, Leigh, M, Martin, T, Millward, H, Motherwell, N, Rikunenko, R, Stickley, J, Summers, J, Ting, L, Tivenan, H, Tonks, L, Wilcox, R, Bokhari, M, Lucas, R, McCormick, W, Ritzema, J, Sanderson, A, Wild, H, Baxter, N, Henderson, S, Kennedy-Hay, S, Rooney, L, Sim, M, McCreath, G, Brunton, M, Caterson, J, Coles, H, Frise, M, Rai, SG, Keating, L, Tilney, E, Bartley, S, Bhuie, P, Downes, C, Holding, K, Riches, K, Hilton, M, Hayman, M, Subramanian, D, Daniel, P, Zitter, L, Benyon, S, Marriott, S, Park, L, Keenan, S, Gordon, E, Quinn, H, Baines, K, Andrew, G, Barclay, L, Callaghan, M, Clark, S, Hope, D, Marshall, L, McCulloch, C, Briton, K, Singleton, J, Birch, S, Simpson, K, Craig, J, Demetriou, C, Eckbad, C, Hierons, S, Howie, L, Mitchard, S, Ramos, L, Serrano-Ruiz, A, White, K, Kelly, F, Amin, V, Anastasescu, E, Anumakonda, V, Karthik, K, Kausar, R, Reid, K, Imeson-Wood, J, Bellini, A, Bryant, J, Pickard, A, Roe, N, Sowter, J, Howlett, A, Criste, K, Cusack, R, Golder, K, Golding, H, Jones, O, Leggett, S, Male, M, Marani, M, Prager, K, Williams, T, Roberts, B, Salmon, K, Gondo, P, Hadebe, B, Kayani, A, Masunda, B, Ahmed, A, Morris, A, Jakkula, S, Long, K, Whiteley, S, Wilby, E, Ogg, B, Moultrie, S, Odam, M, Bewley, J, Garland, Z, Grimmer, L, Gumbrill, B, Sweet, K, Webster, D, Efford, G, Bennett, S, Goodwin, E, Jackson, M, Kent, A, Tibke, C, Woodyatt, W, Zaki, A, Daniel, A, Finn, J, Bremmer, P, Allan, J, Geary, T, Houston, G, Meikle, A, O'Brien, P, Bell, D, Boyle, R, Douglas, K, Glass, L, Lee, E, Lennon, L, Rattray, A, Charnock, R, McFarland, D, Cosgrove, D, Attwood, B, Parsons, P, Carmody, S, Oblak, M, Popescu, M, Thankachen, M, Baruah, R, Morris, S, Ferguson, S, Shepherd, A, Altabaibeh, A, Alvaro, A, Gilbert, K, Ma, L, Mostoles, L, Parmar, C, Jetha, C, Booker, L, Pratley, A, Cosier, T, Millen, G, Schumacher, N, Weston, H, Rand, J, Alex, B, Bach, B, Barclay, WS, Bogaert, D, Chand, M, Cooke, GS, Docherty, AB, Dunning, J, Filipe, ADS, Fletcher, T, Green, CA, Harrison, EM, Hiscox, JA, Ijaz, S, Khoo, S, Lim, WS, Mentzer, AJ, Merson, L, Noursadeghi, M, Moore, SC, Palmarini, M, Paxton, WA, Pollakis, G, Price, N, Rambaut, A, Robertson, DL, Sancho-Shimizu, V, Scott, JT, de Silva, T, Sigfrid, L, Solomon, T, Sriskandan, S, Stuart, D, Tedder, RS, Thomson, EC, Thompson, AAR, Thwaites, RS, Turtle, LCW, Gupta, RK, Palmieri, C, Swann, OV, Zambon, M, Dumas, M-E, Griffin, JL, Takats, Z, Chechi, K, Andrikopoulos, P, Osagie, A, Olanipekun, M, Liggi, S, Lewis, MR, Correia, GDS, Sands, CJ, Takis, P, Maslen, L, Greenhalf, W, Shaw, V, McDonald, SE, Ahmed, KA, Armstrong, JA, Ashworth, M, Asiimwe, IG, Bakshi, S, Barlow, SL, Booth, L, Brennan, B, Bullock, K, Catterall, BWA, Clark, JJ, Clarke, EA, Cox, H, Dincarslan, O, Dunn, C, Dyer, P, Elliott, A, Evans, A, Finch, L, Fisher, LWS, Foster, T, Garcia-Dorival, I, Gunning, P, Hartley, C, Jensen, RL, Jones, CB, Jones, TR, Khandaker, S, Kiy, RT, Koukorava, C, Lake, A, Lant, S, Latawiec, D, Lavelle-Langham, L, Lefteri, D, Lett, L, Livoti, LA, Mancini, M, McDonald, S, McEvoy, L, McLauchlan, J, Metelmann, S, Miah, NS, Middleton, J, Mitchell, J, Murphy, EG, Penrice-Randal, R, Pilgrim, J, Prince, T, Reynolds, W, Ridley, PM, Sales, D, Shaw, VE, Shears, RK, Small, B, Subramaniam, KS, Szemiel, A, Taggart, A, Tanianis-Hughes, J, Trochu, E, van Tonder, L, Wilcock, E, Zhang, JE, Flaherty, L, Maziere, N, Cass, E, Carracedo, AD, Carlucci, N, Holmes, A, Massey, H, Murphy, L, Wrobel, N, McCafferty, S, Morrice, K, MacLean, A, Armstrong, R, Boz, C, Coutts, A, Cullum, L, Day, N, Donnelly, L, Duncan, E, Fawkes, A, Finernan, P, Gilchrist, T, Golightly, A, Hafezi, K, Law, D, Law, R, Law, S, Macgillivray, L, Maclean, A, Mal, H, Mcmaster, E, Meikle, J, Oosthuyzen, W, Paterson, T, Stenhouse, A, Swets, M, Szoor-McElhinney, H, Taneski, F, Wackett, T, Ward, M, Weaver, J, Coyle, J, Gallagher, B, Lidstone-Scott, R, Hamilton, D, Schon, K, Furlong, A, Biggs, H, Griffiths, F, Andrews, E, Brickell, K, Smyth, M, Carson, G, Hardwick, H, Donohue, C, Initiative, CHG, Team, AC, Grp, NS-CS, Force, HCT, Task, HGC, FHoGID, RegCOVID, P-PredictUs, SeroCOVID, CRiPSI, Team, GHR, Working, UCLAHATLASDM, COVID-19 Host Genetics initiative, including authors, Amsterdam Neuroscience - Complex Trait Genetics, Complex Trait Genetics, Internal Medicine, Epidemiology, Oral and Maxillofacial Surgery, UK Research and Innovation, NIHR, UKRI MRC COVID-19 Rapid Response Call, Niemi, Mari E. K., Karjalainen, Juha, Liao, Rachel G., Neale, Benjamin M., Daly, Mark, Ganna, Andrea, Pathak, Gita A., Andrews, Shea J., Kanai, Masahiro, Veerapen, Kumar, Fernandez-Cadenas, Israel, Schulte, Eva C., Striano, Pasquale, Marttila, Minttu, Minica, Camelia, Marouli, Eirini, Karim, Mohd Anisul, Wendt, Frank R., Savage, Jeanne, Sloofman, Laura, Butler-Laporte, Guillaume, Kim, Han-Na, Kanoni, Stavroula, Okada, Yukinori, Byun, Jinyoung, Han, Younghun, Uddin, Mohammed Jashim, Smith, George Davey, Willer, Cristen J., Buxbaum, Joseph D., Mehtonen, Juha, Finucane, Hilary, Cordioli, Mattia, Martin, Alicia R., Zhou, Wei, Pasaniuc, Bogdan, Julienne, Hanna, Aschard, Hugue, Shi, Huwenbo, Yengo, Loic, Polimanti, Renato, Ghoussaini, Maya, Schwartzentruber, Jeremy, Dunham, Ian, Chwialkowska, Karolina, Francescatto, Margherita, Trankiem, Amy, Balaconis, Mary K., Davis, Lea, Lee, Sulggi, Priest, Jame, Renieri, Alessandra, Sankaran, Vijay G., van Heel, David, Deelen, Patrick, Richards, J. Brent, Nakanishi, Tomoko, Biesecker, Le, Kerchberger, V. Eric, Baillie, J. Kenneth, Mari, Francesca, Bernasconi, Anna, Baillie, Stefano Ceri, Canakoglu, Arif, Wolford, Brooke, Faucon, Annika, Dutta, Atanu Kumar, Schurmann, Claudia, Harry, Emi, Birney, Ewan, Nguyen, Huy, Nasir, Jamal, Kaunisto, Mari, Solomonson, Matthew, Dueker, Nicole, Vadgama, Nirmal, Limou, Sophie, Rahmouni, Souad, Mbarek, Hamdi, Darwish, Dima, Uddin, Md Mesbah, Albertos, Raquel, Pérez-Tur, Jordi, Li, Ruolin, Folkersen, Lasse, Moltke, Ida, Koelling, Nil, Teumer, Alexander, Kousathanas, Athanasio, Utrilla, Alicia, Verdugo, Ricardo A., Zárate, Ruth, Medina-Gómez, Carolina, Gómez-Cabrero, David, Carnero-Montoro, Elena, Cadilla, Carmen L., Moreno-Estrada, André, Garmendia, Adriana, Moya, Leire, Sedaghati-Khayat, Bahar, Boua, Palwendé Romuald, Favé, Marie-Julie, Francioli, Laurent, Lemaçon, Audrey, Migeotte, Isabelle, Patel, Sanjay, Varnai, Reka, Szentpeteri, Jozsef L., Sipeky, Csilla, Colombo, Francesca, von Hohenstaufen, Kathrin, Lio, Pietro, Vallerga, Costanza, Wang, Qingbo, Tanigawa, Yosuke, Im, Hogune, Han, Chulho, Song, Han, Lim, Jiwoo, Lee, Younhe, Kim, Sugyeong, Im, Sangyoon, Atanasovska, Biljana, Ahmad, Hajar Fauzan, Boer, Cindy, Jansen, Philip, Franke, Lude, Kaja, Elżbieta, Pasko, Dorota, Kennis-Szilagyi, Ingrid, Kornilov, Sergey A., Prijatelj, Vid, Prokić, Ivana, Sivanadhan, Ilangkumaran, Perumal, Sarala, Esmaeeli, Sahar, Pearson, Nathaniel M., Auton, Adam, Shelton, Janie F., Shastri, Anjali J., Filshtein-Sonmez, Teresa, Coker, Daniella, Symons, Antony, Esparza-Gordillo, Jorge, Aslibekyan, Stella, O’Connell, Jared, Ye, Chelsea, Weldon, Catherine H., Perera, Minoli, O’Leary, Kevin, Tuck, Matthew, O’Brien, Travi, Meltzer, David, O’Donnell, Peter, Nutescu, Edith, Yang, Guang, Alarcon, Cristina, Herrmann, Stefanie, Mazurek, Sophia, Banagan, Jeff, Hamidi, Zacharia, Barbour, April, Raffat, Noora, Moreno, Diana, Friedman, Paula, Ferwerda, Bart, van de Beek, Diederik, Brouwer, Matthijs C., Vlaar, Alexander P. J., Wiersinga, W. Joost, Posthuma, Danielle, Tissink, Elleke, Koos Zwinderman, A. H., Uffelmann, Emil, van Agtmael, Michiel, Algera, Anne Geke, van Baarle, Frank, Bax, Diane, Beudel, Martijn, Jan Bogaard, Harm, Bomers, Marije, Bonta, Peter I., Bos, Lieuwe, Botta, Michela, de Brabander, Justin, de Bree, Godelieve, de Bruin, Sanne, Bugiani, Marianna, Bulle, Esther, Chouchane, Osoul, Cloherty, Alex, Dongelmans, Dave, Elbers, Paul, Fleuren, Luca, Geerlings, Suzanne, Geerts, Bart, Geijtenbeek, Theo, Girbes, Armand, Goorhuis, Bram, Grobusch, Martin P., Hafkamp, Florianne, Hagens, Laura, Hamann, Jorg, Harris, Vanessa, Hemke, Robert, Hermans, Sabine M., Heunks, Leo, Hollmann, Marku, Horn, Janneke, Hovius, Joppe W., de Jong, Menno D., Koning, Rutger, van Mourik, Niel, Nellen, Jeannine, Nossent, Esther J., Paulus, Frederique, Peters, Edgar, van der Poll, Tom, Preckel, Bennedikt, Prins, Jan M., Raasveld, Jorinde, Reijnders, Tom, Schinkel, Michiel, Schultz, Marcus J., Schuurman, Alex, Sigaloff, Kim, Smit, Marry, Stijnis, Cornelis S., Stilma, Willemke, Teunissen, Charlotte, Thoral, Patrick, Tsonas, Anissa, van der Valk, Marc, Veelo, Denise, de Vries, Heder, van Vugt, Michèle, Wouters, Dorien, Minnaar, René P., Kromhout, Adrie, van Uffelen, Kees W. J., Wolterman, Ruud A., Roberts, Genevieve, Park, Danny, Ball, Catherine A., Coignet, Marie, Mccurdy, Shannon, Knight, Spencer, Partha, Raghavendran, Rhead, Brooke, Zhang, Miao, Berkowitz, Nathan, Gaddis, Michael, Noto, Keith, Ruiz, Luong, Pavlovic, Milo, Hong, Eurie L., Rand, Kristin, Girshick, Ahna, Guturu, Harendra, Baltzell, Asher Haug, Guntz, Julien, Beguin, Yve, Pigazzini, Sara, Nkambule, Lindokuhle, Bouysran, Youssef, Busson, Adeline, Peyrassol, Xavier, Wilkin, Françoise, Pichon, Bruno, Smits, Guillaume, Vandernoot, Isabelle, Goffard, Jean-Christophe, Georges, Michel, Moutschen, Michel, Misset, Benoit, Darcis, Gille, Guiot, Julien, Jadot, Laurent, Azarzar, Samira, Dellot, Patricia, Gofflot, Stéphanie, Claassen, Sabine, Bertrand, Axelle, Parzibut, Gille, Clarinval, Mathilde, Moermans, Catherine, Malaise, Olivier, El Kandoussi, Kamilia, Thonon, Raphaël, Huynen, Pascale, Mesdagh, Alyssia, Melo, Sofia, Jacques, Nicola, Di Valentin, Emmanuel, Giroule, Françoi, Collignon, Alice, Radermecker, Coraline, Lebrun, Marielle, Perée, Hélène, Latour, Samuel, Barada, Olivia, Sanchez, Judit, Josse, Claire, Boujemla, Bouchra, Meunier, Margot, Mariavelle, Emeline, Anania, Sandy, Gazon, Hélène, Juszczak, Danusia, Fadeur, Marjorie, Camby, Séverine, Meuris, Christelle, Thys, Marie, Jacques, Jessica, Henket, Monique, Léonard, Philippe, Frippiat, Frederic, Giot, Jean-Baptiste, Sauvage, Anne-Sophie, Von Frenckell, Christian, Mni, Myriam, Wéry, Marie, Staderoli, Alicia, Belhaj, Yasmine, Lambermont, Bernard, Morrison, David R., Mooser, Vincent, Forgetta, Vincenzo, Li, Rui, Ghosh, Biswarup, Laurent, Laetitia, Belisle, Alexandre, Henry, Danielle, Abdullah, Tala, Adeleye, Olumide, Mamlouk, Noor, Kimchi, Nofar, Afrasiabi, Zaman, Rezk, Nardin, Vulesevic, Branka, Bouab, Meriem, Guzman, Charlotte, Petitjean, Loui, Tselios, Chri, Xue, Xiaoqing, Afilalo, Jonathan, Afilalo, Marc, Oliveira, Maureen, Brenner, Bluma, Brassard, Nathalie, Durand, Madeleine, Schurr, Erwin, Lepage, Pierre, Ragoussis, Jianni, Auld, Daniel, Chassé, Michaël, Kaufmann, Daniel E., Lathrop, G. Mark, Adra, Darin, Davis, Lea K., Cox, Nancy J., Below, Jennifer E., Sealock, Julia M., Faucon, Annika B., Shuey, Megan M., Polikowsky, Hannah G., Petty, Lauren E., Shaw, Douglas M., Chen, Hung-Hsin, Zhu, Wanying, Ludwig, Kerstin U., Schröder, Julia, Maj, Carlo, Rolker, Selina, Nöthen, Markus M., Fazaal, Julia, Keitel, Verena, Jensen, Björn-Erik Ole, Feldt, Torsten, Kurth, Ingo, Marx, Nikolau, Dreher, Michael, Pink, Isabell, Cornberg, Marku, Illig, Thoma, Lehmann, Clara, Schommers, Philipp, Augustin, Max, Rybniker, Jan, Knopp, Lisa, Eggermann, Thoma, Volland, Sonja, Altmüller, Janine, Berger, Marc M., Brenner, Thorsten, Hinney, Anke, Witzke, Oliver, Bals, Robert, Herr, Christian, Ludwig, Nicole, Walter, Jörn, Fuchsberger, Christian, Pattaro, Cristian, De Grandi, Alessandro, Pramstaller, Peter, Emmert, David, Melotti, Roberto, Foco, Luisa, Mascalzoni, Deborah, Gögele, Martin, Domingues, Francisco, Hicks, Andrew, Gignoux, Christopher R., Wicks, Stephen J., Crooks, Kristy, Barnes, Kathleen C., Daya, Michelle, Shortt, Jonathan, Rafaels, Nichola, Chavan, Sameer, Goldstein, David B., Kiryluk, Krzysztof, Sengupta, Soumitra, Chung, Wendy, Reilly, Muredach P., Khan, Atla, Wang, Chen, Povysil, Gundula, Bhardwaj, Nitin, Gharavi, Ali G., Ionita-Laza, Iuliana, Shang, Ning, O’Byrne, Sheila M., Nandakumar, Renu, Menon, Amritha, So, Yat S., Hod, Eldad, Pendrick, Danielle, Park, Soo-Kyung, Kim, Hyung-Lae, Kang, Chang Kyung, Lee, Hyo-Jung, Song, Kyoung-Ho, Jae Yoon, Kyung, Paik, Nam-Jong, Seok, Woojin, Yoon, Heejun, Joo, Eun-Jeong, Chang, Yoosoo, Ryu, Seungho, Park, Wan Beom, Su Park, Jeong, Un Park, Kyoung, Ham, Sin Young, Jung, Jongtak, Kim, Eu Suk, Kim, Hong Bin, Ellinghaus, David, Degenhardt, Frauke, Cáceres, Mario, Juzenas, Simona, Lenz, Tobias L., Albillos, Agustín, Julià, Antonio, Heidecker, Bettina, Garcia, Federico, Kurth, Florian, Tran, Florian, Hanses, Frank, Zoller, Heinz, Holter, Jan C., Fernández, Javier, Sander, Leif Erik, Rosenstiel, Philip, Koehler, Philipp, de Cid, Rafael, Asselta, Rosanna, Schreiber, Stefan, Hehr, Ute, Prati, Daniele, Baselli, Guido, Valenti, Luca, Bujanda, Lui, Banales, Jesus M., Duga, Stefano, D’Amato, Mauro, Romero-Gómez, Manuel, Buti, Maria, Invernizzi, Pietro, Franke, Andre, Hov, Johannes R., Karlsen, Tom H., Folseraas, Trine, Maya-Miles, Dougla, Teles, Ana, Azuure, Clinton, Wacker, Eike Matthia, Uellendahl-Werth, Florian, Elabd, Hesham, Arora, Jatin, Lerga-Jaso, Jon, Wienbrandt, Lar, Rühlemann, Malte Christoph, Wendorff, Mareike, Vadla, May Sissel, Lenning, Ole Bernt, Özer, Onur, Myhre, Ronny, Raychaudhuri, Soumya, Tanck, Anja, Gassner, Christoph, Hemmrich-Stanisak, Georg, Kässens, Jan, Figuera Basso, Maria E., Schulzky, Martin, Wittig, Michael, Braun, Nicole, Wesse, Tanja, Albrecht, Wolfgang, Yi, Xiaoli, Ortiz, Aaron Blandino, Chercoles, Adolfo Garrido, Ruiz, Agustín, Mantovani, Alberto, Holten, Aleksander Rygh, Mayer, Alena, Cherubini, Alessandro, Protti, Alessandro, Aghemo, Alessio, Gerussi, Alessio, Ramirez, Alfredo, Braun, Alice, Barreira, Ana, Lleo, Ana, Kildal, Anders Benjamin, Glück, Andrea, Nolla, Anna Carrera, Latiano, Anna, Dyrhol-Riise, Anne Ma, Muscatello, Antonio, Voza, Antonio, Rando-Segura, Ariadna, Solier, Aurora, Karina, Banasik, Cortes, Beatriz, Mateos, Beatriz, Nafria-Jimenez, Beatriz, Schaefer, Benedikt, Bellinghausen, Carla, Ferrando, Carlo, Quereda, Carmen, Skurk, Carsten, Thibeault, Charlotte, Spinner, Christoph D., Lange, Christoph, Hu, Cinzia, Cappadona, Claudio, Bianco, Cristiana, Sancho, Cristina, Lihaug Hoff, Dag Arne, Galimberti, Daniela, Jiménez, David, Pestaña, David, Toapanta, David, Azzolini, Elena, Scarpini, Elio, Helbig, Elisa T., Urrechaga, Eloisa, Paraboschi, Elvezia Maria, Pontali, Emanuele, Reverter, Enric, Navas, Enrique, Arana, Eunate, Sánchez, Félix García, Ceriotti, Ferruccio, Malvestiti, Francesco, Mesonero, Francisco, Pezzoli, Gianni, Lamorte, Giuseppe, Neb, Holger, My, Ilaria, Hernández, Isabel, de Rojas, Itziar, Galván-Femenia, Iván, Heyckendorf, Jan, Badia, Joan Ramon, Schneider, Jochen, Goikoetxea, Josune, Kraft, Julia, Müller, Karl Erik, Gaede, Karoline I., Garcia-Etxebarria, Koldo, Tonby, Kristian, Heggelund, Lar, Izquierdo-Sanchez, Laura, Sumoy, Lauro, Lippert, Lena J., Terranova, Leonardo, Garbarino, Lucia, Téllez, Lui, Roade, Luisa, Ostadreza, Mahnoosh, Intxausti, Maider, Kogevinas, Manoli, Gutiérrez-Stampa, María A., Vehreschild, Maria J. G. T., Marquié, Marta, Castoldi, Massimo, Cecconi, Maurizio, Boada, Mercè, Seilmaier, Michael J., Mazzocco, Michela, Rodríguez-Gandía, Miguel, Ayo, Natale Imaz, Blay, Natalia, Martínez, Nilda, Cornely, Oliver A., Palmieri, Orazio, Tentorio, Paolo, Rodrigues, Pedro M., España, Pedro P., Hoffmann, Per, Bacher, Petra, Suwalski, Phillip, de Pablo, Raúl, Nieto, Rosa, Badalamenti, Salvatore, Ciesek, Sandra, Bombace, Sara, Wilfling, Sibylle, Brunak, Søren, Heilmann-Heimbach, Stefanie, Ripke, Stephan, Bahmer, Thoma, Landmesser, Ulf, Protzer, Ulrike, Rimoldi, Valeria, Skogen, Vegard, Andrade, Victor, Moreno, Victor, Poller, Wolfgang, Farre, Xavier, Wang, Xiaomin, Khodamoradi, Yascha, Karadeniz, Zehra, de Salazar, Adolfo, Palom, Adriana, Garcia-Fernandez, Alba-Estela, Blanco-Grau, Albert, Zanella, Alberto, Bandera, Alessandra, Nebel, Almut, Biondi, Andrea, Caballero-Garralda, Andrea, Gori, Andrea, Lind, Andrea, Fracanzani, Anna Ludovica, Peschuck, Anna, Pesenti, Antonio, de la Horra, Carmen, Milani, Chiara, Paccapelo, Cinzia, Angelini, Claudio, Cea, Cristina, Muñiz-Diaz, Eduardo, Sandoval, Elena, Calderón, Enrique J., Solligård, Erik, Aziz, Fátima, Martinelli-Boneschi, Filippo, Peyvandi, Flora, Blasi, Francesco, Medrano, Francisco J., Rodriguez-Frias, Francisco, Müller, Fredrik, Grasselli, Giacomo, Costantino, Giorgio, Cardamone, Giulia, Foti, Giuseppe, Matullo, Giuseppe, Kurihara, Hayato, Afset, Jan Egil, Damås, Jan Kristian, Ampuero, Javier, Martín, Javier, Erdmann, Jeanette, Bergan, Jona, Goerg, Siegfried, Ferrusquía-Acosta, Jose, Quero, Jose Hernández, Delgado, Juan, Guerrero, Juan M., Risnes, Kari, Bettini, Laura Rachele, Moreira, Leticia, Gustad, Lise Tuset, Santoro, Luigi, Scudeller, Luigia, Riveiro-Barciela, Mar, Schaefer, Marco, Carrabba, Maria, Valsecchi, Maria G., Hernandez-Tejero, María, Acosta-Herrera, Marialbert, D’Angiò, Mariella, Baldini, Marina, Cazzaniga, Marina, Ciccarelli, Michele, Bocciolone, Monica, Miozzo, Monica, Chueca, Natalia, Montano, Nicola, Faverio, Paola, Preatoni, Paoletta, Bonfanti, Paolo, Omodei, Paolo, Castro, Pedro, Ferrer, Ricard, Gualtierotti, Roberta, Gallego-Durán, Rocío, Morilla, Rubén, Haider, Sammra, Marsal, Sara, Aneli, Serena, Pelusi, Serena, Bosari, Silvano, Aliberti, Stefano, Dudman, Susanne, Zheng, Tenghao, Pumarola, Toma, Cejudo, Trinidad Gonzalez, Monzani, Valter, Friaza, Vicente, Peter, Wolfgang, Dopazo, Ximo, May, Sandra, Grimsrud, Marit M., Gudbjartsson, Daniel F., Stefansson, Kari, Sulem, Patrick, Sveinbjornsson, Gardar, Melsted, Pall, Norddahl, Gudmundur, Swerford Moore, Kristjan Helgi, Thorsteinsdottir, Unnur, Holm, Hilma, Alarcón-Riquelme, Marta E., Bernardo, David, Martínez-Bueno, Manuel, Rello, Silvia Rojo, Magi, Reedik, Milani, Lili, Metspalu, Andre, Laisk, Triin, Läll, Kristi, Lepamets, Maarja, Esko, Tõnu, Reimann, Ene, Naaber, Paul, Laane, Edward, Pesukova, Jaana, Peterson, Pärt, Kisand, Kai, Tabri, Jekaterina, Allos, Raili, Hensen, Kati, Starkopf, Joel, Ringmets, Inge, Tamm, Anu, Kallaste, Anne, Alavere, Helene, Metsalu, Kristjan, Puusepp, Mairo, Kristiansson, Kati, Koskelainen, Sami, Perola, Marku, Donner, Kati, Kivinen, Katja, Palotie, Aarno, Rivolta, Carlo, Bochud, Pierre-Yve, Bibert, Stéphanie, Boillat, Noémie, Nussle, Semira Gonseth, Albrich, Werner, Quinodoz, Mathieu, Kamdar, Dhryata, Suh, Noémie, Neofytos, Dionysio, Erard, Véronique, Voide, Cathy, Bochud, P. Y., Rivolta, C., Bibert, S., Quinodoz, M., Kamdar, D., Neofytos, D., Erard, V., Voide, C., Friolet, R., Vollenweider, P., Pagani, J. L., Oddo, M., zu Bentrup, F. Meyer, Conen, A., Clerc, O., Marchetti, O., Guillet, A., Guyat-Jacques, C., Foucras, S., Rime, M., Chassot, J., Jaquet, M., Viollet, R. Merlet, Lannepoudenx, Y., Portopena, L., Desgranges, F., Filippidis, P., Guéry, B., Haefliger, D., Kampouri, E. E., Manuel, O., Munting, A., Papadimitriou-Olivgeris, M., Regina, J., Rochat-Stettler, L., Suttels, V., Tadini, E., Tschopp, J., Van Singer, M., Viala, B., Boillat-Blanco, N., Brahier, T., Hügli, O., Meuwly, J. Y., Pantet, O., Nussle, S. Gonseth, Bochud, M., D’Acremont, V., Younes, S. Estoppey, Albrich, W. C., Suh, N., Cerny, A., O’Mahony, L., von Mering, C., Frischknecht, M., Kleger, G. -R., Filipovic, M., Kahlert, C. R., Wozniak, H., Negro, T. Rochat, Pugin, J., Bouras, K., Knapp, C., Egger, T., Perret, A., Montillier, P., di Bartolomeo, C., Barda, B., Carreras, Anna, Galván-Femenía, Iván, Farré, Xavier, Cortés, Beatriz, Mercader, Josep Maria, Guindo-Martinez, Marta, Torrents, David, Garcia-Aymerich, Judith, Castaño-Vinyals, Gemma, Dobaño, Carlota, Gori, Marco, Mondelli, Mario Umberto, Castelli, Francesco, Vaghi, Massimo, Rusconi, Stefano, Montagnani, Francesca, Bargagli, Elena, Franchi, Federico, Mazzei, Maria Antonietta, Cantarini, Luca, Tacconi, Danilo, Feri, Marco, Scala, Raffaele, Spargi, Genni, Nencioni, Cesira, Bandini, Maria, Caldarelli, Gian Piero, Spagnesi, Maurizio, Canaccini, Anna, Ognibene, Agostino, D’Arminio Monforte, Antonella, Girardis, Massimo, Antinori, Andrea, Francisci, Daniela, Schiaroli, Elisabetta, Scotton, Pier Giorgio, Panese, Sandro, Scaggiante, Renzo, Monica, Matteo Della, Capasso, Mario, Fiorentino, Giuseppe, Castori, Marco, Aucella, Filippo, Di Biagio, Antonio, Masucci, Luca, Valente, Serafina, Mandalà, Marco, Zucchi, Patrizia, Giannattasio, Ferdinando, Coviello, Domenico A., Mussini, Cristina, Bosio, Giancarlo, Tavecchia, Luisa, Crotti, Lia, Rizzi, Marco, La Rovere, Maria Teresa, Sarzi-Braga, Simona, Bussotti, Maurizio, Ravaglia, Sabrina, Artuso, Rosangela, Perrella, Antonio, Romani, Davide, Bergomi, Paola, Catena, Emanuele, Vincenti, Antonella, Ferri, Claudio, Grassi, Davide, Pessina, Gloria, Tumbarello, Mario, Di Pietro, Massimo, Sabrina, Ravaglia, Luchi, Sauro, Barbieri, Chiara, Acquilini, Donatella, Andreucci, Elena, Paciosi, Francesco, Segala, Francesco Vladimiro, Tiseo, Giusy, Falcone, Marco, Lista, Mirjam, Poscente, Monica, De Vivo, Oreste, Petrocelli, Paola, Guarnaccia, Alessandra, Baroni, Silvia, Perticaroli, Valentina, Furini, Simone, Dei, Simona, Benetti, Elisa, Picchiotti, Nicola, Sanarico, Maurizio, Ceri, Stefano, Pinoli, Pietro, Raimondi, Francesco, Biscarini, Filippo, Stella, Alessandra, Bergomi, Mattia, Zguro, Kristina, Capitani, Katia, Tanfoni, Marco, Fallerini, Chiara, Daga, Sergio, Baldassarri, Margherita, Fava, Francesca, Frullanti, Elisa, Valentino, Floriana, Doddato, Gabriella, Giliberti, Annarita, Tita, Rossella, Amitrano, Sara, Bruttini, Mirella, Croci, Susanna, Meloni, Ilaria, Mencarelli, Maria Antonietta, Lo Rizzo, Caterina, Pinto, Anna Maria, Beligni, Giada, Tommasi, Andrea, Di Sarno, Laura, Palmieri, Maria, Carriero, Miriam Lucia, Alaverdian, Diana, Iuso, Nicola, Inchingolo, Gabriele, Busani, Stefano, Bruno, Raffaele, Vecchia, Marco, Belli, Mary Ann, Mantovani, Stefania, Ludovisi, Serena, Quiros-Roldan, Eugenia, Antoni, Melania Degli, Zanella, Isabella, Siano, Matteo, Emiliozzi, Arianna, Fabbiani, Massimiliano, Rossetti, Barbara, Zanelli, Giacomo, Bergantini, Laura, D’Alessandro, Miriana, Cameli, Paolo, Bennet, David, Anedda, Federico, Marcantonio, Simona, Scolletta, Sabino, Guerrini, Susanna, Conticini, Edoardo, Frediani, Bruno, Spertilli, Chiara, Donati, Alice, Guidelli, Luca, Corridi, Marta, Croci, Leonardo, Piacentini, Paolo, Desanctis, Elena, Cappelli, Silvia, Verzuri, Agnese, Anemoli, Valentina, Pancrazi, Alessandro, Lorubbio, Maria, Merlini, Esther, Miraglia, Federica Gaia, Venturelli, Sophie, Cossarizza, Andrea, Vergori, Alessandra, Gabrieli, Arianna, Riva, Agostino, Andretta, Francesca, Gatti, Francesca, Parisi, Saverio Giuseppe, Baratti, Stefano, Piscopo, Carmelo, Russo, Roberta, Andolfo, Immacolata, Iolascon, Achille, Carella, Massimo, Merla, Giuseppe, Squeo, Gabriella Maria, Raggi, Pamela, Marciano, Carmen, Perna, Rita, Bassetti, Matteo, Sanguinetti, Maurizio, Giorli, Alessia, Salerni, Lorenzo, Parravicini, Pierpaolo, Menatti, Elisabetta, Trotta, Tullio, Coiro, Gabriella, Lena, Fabio, Martinelli, Enrico, Mancarella, Sandro, Gabbi, Chiara, Maggiolo, Franco, Ripamonti, Diego, Bachetti, Tiziana, Suardi, Claudia, Parati, Gianfranco, Bottà, Giordano, Di Domenico, Paolo, Rancan, Ilaria, Bianchi, Francesco, Colombo, Riccardo, van Heel, David A., Hunt, Karen A., Trembath, Richard C., Huang, Qin Qin, Martin, Hilary C., Mason, Dan, Trivedi, Bhavi, Wright, John, Finer, Sarah, Griffiths, Christopher J., Akhtar, Shaheen, Anwar, Mohammad, Arciero, Elena, Ashraf, Samina, Breen, Gerome, Chung, Raymond, Curtis, Charles J., Chowdhury, Maharun, Colligan, Grainne, Deloukas, Pano, Durham, Ceri, Griffiths, Chri, Hurles, Matt, Hussain, Shapna, Islam, Kamrul, Khan, Ahsan, Khan, Amara, Lavery, Cath, Lee, Sang Hyuck, Lerner, Robin, Macarthur, Daniel, Maclaughlin, Bev, Martin, Hilary, Miah, Shefa, Newman, Bill, Safa, Nishat, Tahmasebi, Farah, Smith, Albert V., Boughton, Andrew P., Li, Kevin W., Lefaive, Jonathon, Annis, Aubrey, Jannes, Cinthia E., Krieger, Jose E., Pereira, Alexandre C., Velho, Mariliza, Marques, Emanuelle, Lima, Isabella Ramo, Tada, Mauricio Teruo, Valino, Karina, Mccarthy, Mark, Rosenberger, Carrie, Lee, Jong Eun, Chang, Diana, Hammer, Christian, Hunkapiller, Julie, Mahajan, Anubha, Pendergrass, Sarah, Sucheston-Campbell, Lara, Yaspan, Brian, Lee, Hyun Soo, Shin, Eunsoon, Jang, Hye Yoon, Kim, Sunmie, Kym, Sungmin, Kim, Yeon-Sook, Jeong, Hyeongseok, Kwon, Ki Tae, Kim, Shin-Woo, Kim, Jin Yong, Jang, Young Rock, Kim, Hyun ah, Lee, Ji Yeon, Lee, Jeong Eun, Lee, Shinwon, Choe, Kang-Won, Kang, Yu Min, Jee, Sun Ha, Jung, Keum Ji, Parikh, Victoria, Ashley, Euan, Wheeler, Matthew, Rivas, Manuel, Bustamante, Carlo, Pinksy, Benjamin, Febbo, Phillip, Farh, Kyle, Schroth, Gary P., Desouza, Franci, Dalton, Karen, Christle, Jeff, Deboever, Christopher, Szalma, Sándor, Rubinacci, Simone, Delaneau, Olivier, Gorzynski, John, de Jong, Hannah, Sutton, Shirley, Youlton, Nathan, Joshi, Ruchi, Jimenez-Morales, David, Hughes, Christopher, Amar, David, Ioannidis, Alex, Hershman, Steve, Kirillova, Anna, Seo, Kinya, Huang, Yong, Shoura, Massa, Hammond, Nathan, Watson, Nathaniel, Raja, Archana, Huang, Chunhong, Sahoo, Malaya, Wang, Hannah, Zhen, Jimmy, Rakitko, Alexander, Ilinsky, Valery, Yermakovich, Danat, Popov, Iaroslav, Chernitsov, Alexander, Kovalenko, Elena, Krasnenko, Anna, Plotnikov, Nikolay, Stetsenko, Ivan, Kim, Anna, Cirulli, Elizabeth T., Schiabor Barrett, Kelly M., Bolze, Alexandre, White, Simon, Washington, Nicole L., Lu, James T., Riffle, Stephen, Tanudjaja, Francisco, Wang, Xueqing, Ramirez, Jimmy M., Leonetti, Nicole, Sandoval, Efren, Neveux, Iva, Dabe, Shaun, Grzymski, Joseph J., Esteban Miñano, Juan Ignacio, Aguirre, Luis A., López-Collazo, Eduardo, de la Mata Pazos, Manuel, Cerrato, Luciano, Lozano-Rodríguez, Roberto, Avendaño-Ortiz, José, Arcos, Verónica Terrón, Montalbán-Hernández, Karla Marina, Quiroga, Jaime Valentín, Pascual-Iglesias, Alejandro, Maroun-Eid, Charbel, Martín-Quirós, Alejandro, Namkoong, Ho, Imoto, Seiya, Katayama, Kazuhiko, Fukunaga, Koichi, Kitagawa, Yuko, Sato, Toshiro, Hasegawa, Naoki, Kumanogoh, Atsushi, Kimura, Akinori, Ai, Masumi, Tokunaga, Katsushi, Kanai, Takanori, Miyano, Satoru, Ogawa, Seishi, Edahiro, Ryuya, Sonehara, Kyuto, Shirai, Yuya, Ishii, Makoto, Kabata, Hiroki, Masaki, Katsunori, Kamata, Hirofumi, Ikemura, Shinnosuke, Chubachi, Shotaro, Okamori, Satoshi, Terai, Hideki, Tanaka, Hiromu, Morita, Atsuho, Lee, Ho, Asakura, Takanori, Sasaki, Junichi, Morisaki, Hiroshi, Uwamino, Yoshifumi, Nanki, Kosaku, Mikami, Yohei, Tomono, Kazunori, Kato, Kazuto, Matsuda, Fumihiko, Takahashi, Meiko, Hizawa, Nobuyuki, Takeda, Yoshito, Hirata, Haruhiko, Shiroyama, Takayuki, Miyawaki, Satoru, Suzuki, Ken, Maeda, Yuichi, Nii, Takuro, Noda, Yoshimi, Niitsu, Takayuki, Adachi, Yuichi, Enomoto, Takatoshi, Amiya, Saori, Hara, Reina, Takahashi, Kunihiko, Anzai, Tatsuhiko, Hasegawa, Takanori, Ito, Satoshi, Koike, Ryuji, Endo, Akifumi, Uchimura, Yuji, Miyazaki, Yasunari, Honda, Takayuki, Tateishi, Tomoya, Tohda, Shuji, Ichimura, Naoya, Sonobe, Kazunari, Sassa, Chihiro, Nakajima, Jun, Nannya, Yasuhito, Omae, Yosuke, Takahashi, Kazuhisa, Harada, Norihiro, Hiki, Makoto, Takagi, Haruhi, Nakamura, Ai, Tagaya, Etsuko, Kawana, Masatoshi, Arimura, Ken, Ishiguro, Takashi, Takayanagi, Noboru, Isono, Taisuke, Takaku, Yotaro, Takano, Kenji, Anan, Ryusuke, Nakajima, Yukiko, Nakano, Yasushi, Nishio, Kazumi, Ueda, Soichiro, Hayashi, Reina, Tateno, Hiroki, Hase, Isano, Yoshida, Shuichi, Suzuki, Shoji, Mitamura, Keiko, Saito, Fumitake, Ueda, Tetsuya, Azuma, Masanori, Nagasaki, Tadao, Yasui, Yoshinori, Hasegawa, Yoshinori, Mutoh, Yoshikazu, Yoshiyama, Takashi, Shoko, Tomohisa, Kojima, Mitsuaki, Adachi, Tomohiro, Ishikawa, Motonao, Takahashi, Kenichiro, Watanabe, Kazuyoshi, Manabe, Tadashi, Ito, Fumimaro, Fukui, Takahiro, Funatsu, Yohei, Koh, Hidefumi, Hirai, Yoshihiro, Kawashima, Hidetoshi, Narita, Atsuya, Niwa, Kazuki, Sekikawa, Yoshiyuki, Saito, Fukuki, Yoshiya, Kazuhisa, Yoshihara, Tomoyuki, Suzuki, Yusuke, Nakayama, Sohei, Masuzawa, Keita, Nishi, Koichi, Nishitsuji, Masaru, Tani, Maiko, Inoue, Takashi, Hirano, Toshiyuki, Kobayashi, Keigo, Miyazawa, Naoki, Kimura, Yasuhiro, Sado, Reiko, Ogura, Takashi, Kitamura, Hideya, Murohashi, Kota, Nakachi, Ichiro, Baba, Rie, Arai, Daisuke, Fuke, Satoshi, Saito, Hiroshi, Kuwahara, Naota, Fujiwara, Akiko, Okada, Takenori, Baba, Tomoya, Noda, Junya, Mashimo, Shuko, Yagi, Kazuma, Shiomi, Tetsuya, Hashiguchi, Mizuha, Odani, Toshio, Mochimaru, Takao, Oyamada, Yoshitaka, Mori, Nobuaki, Izumi, Namiki, Nagata, Kaoru, Taki, Reiko, Murakami, Koji, Yamada, Mitsuhiro, Sugiura, Hisatoshi, Hayashi, Kentaro, Shimizu, Tetsuo, Gon, Yasuhiro, Fujitani, Shigeki, Tsuchida, Tomoya, Yoshida, Toru, Kagaya, Takashi, Kita, Toshiyuki, Sakagami, Satoru, Kimizuka, Yoshifumi, Kawana, Akihiko, Nakamura, Yoshihiko, Ishikura, Hiroyasu, Takata, Tohru, Kikuchi, Takahide, Taniyama, Daisuke, Nakamura, Morio, Kodama, Nobuhiro, Kaneyama, Yasunari, Maeda, Shunsuke, Nagasaki, Yoji, Okamoto, Masaki, Ishihara, Sayoko, Ito, Akihiro, Chihara, Yusuke, Takeuchi, Mayumi, Onoi, Keisuke, Hashimoto, Naozumi, Wakahara, Keiko, Ando, Akira, Masuda, Makoto, Wakabayashi, Aya, Watanabe, Hiroki, Sageshima, Hisako, Nakada, Taka-Aki, Abe, Ryuzo, Shimada, Tadanaga, Kawamura, Kodai, Ichikado, Kazuya, Nishiyama, Kenta, Yamasaki, Masaki, Hashimoto, Satoru, Kusaka, Yu, Ohba, Takehiko, Isogai, Susumu, Takada, Minoru, Kanda, Hidenori, Komase, Yuko, Sano, Fumiaki, Asano, Koichiro, Oguma, Tsuyoshi, Harada, Masahiro, Takahashi, Takeshi, Shibusawa, Takayuki, Abe, Shinji, Kono, Yuta, Togashi, Yuki, Izumo, Takehiro, Inomata, Minoru, Awano, Nobuyasu, Ogawa, Shinichi, Ogata, Tomouki, Ishihara, Shoichiro, Kanehiro, Arihiko, Ozaki, Shinji, Fuchimoto, Yasuko, Kitagawa, Yuichiro, Yoshida, Shozo, Ogura, Shinji, Nishiyama, Kei, Yoshida, Kousuke, Beppu, Satoru, Fukuyama, Satoru, Eriguchi, Yoshihiro, Yonekawa, Akiko, Inoue, Yoshiaki, Yamagata, Kunihiro, Chiba, Shigeru, Narumoto, Osamu, Nagai, Hideaki, Ooshima, Nobuharu, Motegi, Mitsuru, Sagara, Hironori, Tanaka, Akihiko, Ohta, Shin, Shibata, Yoko, Tanino, Yoshinori, Sato, Yuki, Yamada, Yuichiro, Hashino, Takuya, Shinoki, Masato, Iwagoe, Hajime, Imamura, Tomonori, Umeda, Akira, Shimada, Hisato, Endo, Mayu, Hayashi, Shinichi, Takahashi, Mai, Nakano, Shigefumi, Yatomi, Masakiyo, Maeno, Toshitaka, Ishii, Tomoo, Utsugi, Mitsuyoshi, Ono, Akihiro, Kanaoka, Kensuke, Ihara, Shoichi, Komuta, Kiyoshi, Boezen, Marike, Claringbould, Annique, Lopera, Esteban, Warmerdam, Robert, Vonk, Judith. M., van Blokland, Irene, Lanting, Pauline, Ori, Anil P. S., Obeidat, Ma’En, Hernández Cordero, Ana I., Sin, Don D., Bossé, Yohan, Joubert, Philippe, Hao, Ke, Nickle, David, Timens, Wim, van den Berge, Maarten, Feng, Yen-Chen Anne, Mercader, Josep, Weiss, Scott T., Karlson, Elizabeth W., Smoller, Jordan W., Murphy, Shawn N., Meigs, James B., Woolley, Ann E., Green, Robert C., Perez, Emma F., Zöllner, Sebastian, Wang, Jiongming, Beck, Andrew, Sloofman, Laura G., Ascolillo, Steven, Sebra, Robert P., Collins, Brett L., Levy, Te, Sealfon, Stuart C., Jordan, Daniel M., Thompson, Ryan C., Gettler, Kyle, Chaudhary, Kumardeep, Belbin, Gillian M., Preuss, Michael, Hoggart, Clive, Choi, Sam, Underwood, Slayton J., Salib, Irene, Britvan, Bari, Keller, Katherine, Tang, Lara, Peruggia, Michael, Hiester, Liam L., Niblo, Kristi, Aksentijevich, Alexandra, Labkowsky, Alexander, Karp, Avromie, Zlatopolsky, Menachem, Zyndorf, Marissa, Charney, Alexander W., Beckmann, Noam D., Schadt, Eric E., Abul-Husn, Noura S., Cho, Judy H., Itan, Yuval, Kenny, Eimear E., Loos, Ruth J. F., Nadkarni, Girish N., Do, Ron, O’Reilly, Paul, Huckins, Laura M., Ferreira, Manuel A. R., Abecasis, Goncalo R., Leader, Joseph B., Cantor, Michael N., Justice, Anne E., Carey, Dave J., Chittoor, Geetha, Josyula, Navya Shilpa, Kosmicki, Jack A., Horowitz, Julie E., Baras, Ari, Gass, Matthew C., Yadav, Ashish, Mirshahi, Tooraj, Jan Hottenga, Jouke, Bartels, Meike, de Geus, Eco J. C., Nivard, Michel G., Verma, Anurag, Ritchie, Marylyn D., Rader, Daniel, Li, Binglan, Verma, Shefali S., Lucas, Anastasia, Bradford, Yuki, Zara, Federico, Salpietro, Vincenzo, Scala, Marcello, Iacomino, Michele, Scudieri, Paolo, Bocciardi, Renata, Minetti, Carlo, Riva, Antonella, Vari, Maria Stella, Rahier, Jean-Françoi, Giorgio, Elisa, Carli, Diana, Louis, Edouad, Bulik, Cynthia M., Landén, Mikael, Brusco, Alfredo, Ferrero, Giovanni Battista, Madia, Francesca, Fundín, Bengt, Ismail, Said I., Saad, Chadi, Al-Sarraj, Yaser, Badji, Radja Messai, Al-Muftah, Wadha, Al Thani, Asma, Afifi, Nahla, Klovins, Jani, Rovite, Vita, Rescenko, Raimond, Peculis, Raiti, Ustinova, Monta, Zeberg, Hugo, Frithiof, Robert, Hultström, Michael, Lipcsey, Miklo, Johnson, Ruth, Geschwind, Daniel H., Freimer, Nelson, Butte, Manish J., Ding, Yi, Chiu, Alec, Chang, Timothy S., Boutros, Paul, Moutsianas, Louka, Caulfield, Mark J., Scott, Richard H., Walker, Susan, Stuckey, Alex, Odhams, Christopher A., Rhodes, Daniel, Fowler, Tom, Rendon, Augusto, Chan, Georgia, Arumugam, Prabhu, Karczewski, Konrad J., Wilson, Daniel J., Spencer, Chris A., Crook, Derrick W., Wyllie, David H., O’Connell, Anne Marie, Atkinson, Elizabeth G., Tsuo, Kristin, Baya, Nikola, Turley, Patrick, Gupta, Rahul, Walters, Raymond K., Palmer, Duncan S., Sarma, Gopal, Cheng, Nathan, Lu, Wenhan, Churchhouse, Claire, Goldstein, Jacqueline I., King, Daniel, Seed, Cotton, Daly, Mark J., Bryant, Sam, Satterstrom, F. Kyle, Band, Gavin, Earle, Sarah G., Lin, Shang-Kuan, Arning, Nicola, Armstrong, Jacob, Rudkin, Justine K., Callier, Shawneequa, Cusick, Caroline, Soranzo, Nicole, Zhao, Jing Hua, Danesh, John, Di Angelantonio, Emanuele, Butterworth, Adam S., Sun, Yan V., Huffman, Jennifer E., Cho, Kelly, O’Donnell, Christopher J., Tsao, Phil, Gaziano, J. Michael, Peloso, Gina, Ho, Yuk-Lam, Mian, Michael, Scaggiante, Federica, Chang, Xiao, Glessner, Joseph R., Hakonarson, Hakon, Mcguigan, Peter J., Prockter Moore, Luke Stephen, Vizcaychipi, Marcela Paola, Hall, Kathryn, Campbell, Andy, Nichol, Ailstair, Ward, Geraldine, Page, Valerie Joan, Semple, Malcolm G., Adeniji, Kayode, Agranoff, Daniel, Agwuh, Ken, Ail, Dhiraj, Aldera, Erin L., Alegria, Ana, Angus, Brian, Ashish, Abdul, Atkinson, Dougal, Bari, Shahedal, Barlow, Gavin, Barnass, Stella, Barrett, Nichola, Bassford, Christopher, Basude, Sneha, Baxter, David, Beadsworth, Michael, Bernatoniene, Jolanta, Berridge, John, Best, Nicola, Bothma, Pieter, Chadwick, David, Brittain-Long, Robin, Bulteel, Naomi, Burden, Tom, Burtenshaw, Andrew, Caruth, Vikki, Chambler, Duncan, Chee, Nigel, Child, Jenny, Chukkambotla, Srikanth, Clark, Tom, Collini, Paul, Cosgrove, Catherine, Cupitt, Jason, Cutino-Moguel, Maria-Teresa, Dark, Paul, Dawson, Chri, Dervisevic, Samir, Donnison, Phil, Douthwaite, Sam, Drummond, Andrew, Durand, Ingrid, Dushianthan, Ahilanadan, Dyer, Tristan, Evans, Cariad, Eziefula, Chi, Fegan, Christopher, Finn, Adam, Fullerton, Duncan, Garg, Sanjeev, Garg, Atul, Gkrania-Klotsas, Effrossyni, Godden, Jo, Goldsmith, Arthur, Graham, Clive, Hardy, Elaine, Hartshorn, Stuart, Harvey, Daniel, Havalda, Peter, Hawcutt, Daniel B., Hobrok, Maria, Hodgson, Luke, Hormis, Anil, Jacobs, Michael, Jain, Susan, Jennings, Paul, Kaliappan, Agilan, Kasipandian, Vidya, Kegg, Stephen, Kelsey, Michael, Kendall, Jason, Kerrison, Caroline, Kerslake, Ian, Koch, Oliver, Koduri, Gouri, Koshy, George, Laha, Shondipon, Laird, Steven, Larkin, Susan, Leiner, Tama, Lillie, Patrick, Limb, Jame, Linnett, Vanessa, Little, Jeff, Lyttle, Mark, Macmahon, Michael, Macnaughton, Emily, Mankregod, Ravish, Masson, Huw, Matovu, Elijah, Mccullough, Katherine, Mcewen, Ruth, Meda, Manjula, Mills, Gary H., Minton, Jane, Ward, Karl, Mirfenderesky, Mariyam, Mohandas, Kavya, Mok, Quen, Moon, Jame, Moore, Elinoor, Morgan, Patrick, Morris, Craig, Mortimore, Katherine, Moses, Samuel, Mpenge, Mbiye, Mulla, Rohinton, Murphy, Michael, Nagel, Megan, Nagarajan, Thapa, Nelson, Mark, O’Shea, Matthew K., Otahal, Igor, Ostermann, Marlie, Pais, Mark, Panchatsharam, Selva, Papakonstantinou, Danai, Paraiso, Hassan, Patel, Brij, Pattison, Natalie, Pepperell, Justin, Peters, Mark, Phull, Mandeep, Pintus, Stefania, Pooni, Jagtur Singh, Post, Frank, Price, David, Prout, Rachel, Rae, Nikola, Reschreiter, Henrik, Reynolds, Tim, Richardson, Neil, Roberts, Mark, Roberts, Devender, Rose, Alistair, Rousseau, Guy, Ryan, Brendan, Saluja, Taranprit, Shah, Aarti, Shanmuga, Prad, Sharma, Anil, Shawcross, Anna, Sizer, Jeremy, Shankar-Hari, Manu, Smith, Richard, Snelson, Catherine, Spittle, Nick, Staines, Nikki, Stambach, Tom, Stewart, Richard, Subudhi, Pradeep, Szakmany, Tama, Tatham, Kate, Thomas, Jo, Thompson, Chri, Thompson, Robert, Tridente, Ascanio, Tupper-Carey, Darell, Twagira, Mary, Ustianowski, Andrew, Vallotton, Nick, Vincent-Smith, Lisa, Visuvanathan, Shico, Vuylsteke, Alan, Waddy, Sam, Wake, Rachel, Walden, Andrew, Welters, Ingeborg, Whitehouse, Tony, Whittaker, Paul, Whittington, Ashley, Papineni, Padmasayee, Wijesinghe, Meme, Williams, Martin, Wilson, Lawrence, Cole, Sarah, Winchester, Stephen, Wiselka, Martin, Wolverson, Adam, Wooton, Daniel G., Workman, Andrew, Yates, Bryan, Young, Peter, Beale, Rupert, Bretherick, Andrew D., Clohisey, Sara, Fourman, Max Head, Furniss, Jame, Gountouna, Elvina, Grimes, Graeme, Haley, Chri, Harrison, David, Hayward, Caroline, Keating, Sean, Klaric, Lucija, Klenerman, Paul, Law, Andy, Meynert, Alison M., Millar, Jonathan, Pairo-Castineira, Erola, Parkinson, Nichola, Ponting, Chris P., Porteous, David J., Rawlik, Konrad, Richmond, Anne, Rowan, Kathy, Russell, Clark D., Shen, Xia, Shih, Barbara, Tenesa, Albert, Vitart, Veronique, Wang, Bo, Wilson, James F., Wu, Yang, Yang, Jian, Yang, Zhijian, Zechner, Marie, Zhai, Ranran, Zheng, Chenqing, Norman, Lisa, Pius, Riinu, Drake, Thomas M., Fairfield, Cameron J., Knight, Stephen R., Mclean, Kenneth A., Murphy, Derek, Shaw, Catherine A., Dalton, Jo, Girvan, Michelle, Saviciute, Egle, Roberts, Stephanie, Harrison, Janet, Marsh, Laura, Connor, Marie, Halpin, Sophie, Jackson, Clare, Gamble, Carrol, Leeming, Gary, Law, Andrew, Wham, Murray, Hendry, Ro, Scott-Brown, Jame, Begg, Colin, Hinds, Charle, Wai Ho, Antonia Ying, Horby, Peter W., Knight, Julian, Ling, Lowell, Maslove, David, Mcauley, Danny, Montgomery, Hugh, Nichol, Alistair, Openshaw, Peter J. M., Summers, Charlotte, Walsh, Timothy, Armstrong, Lisa, Bates, Hayley, Dooks, Emma, Farquhar, Fiona, Hairsine, Brigid, Mcparland, C., Packham, Sophie, Alldis, Zoe, Astin-Chamberlain, Raine, Bibi, Fatima, Biddle, Jack, Blow, Sarah, Bolton, Matthew, Borra, Catherine, Bowles, Ruth, Burton, Maudrian, Choudhury, Yasmin, Collier, David, Cox, Amber, Easthope, Amy, Ebano, Patrizia, Fotiadis, Stavro, Gurasashvili, Jana, Halls, Rosslyn, Hartridge, Pippa, Kallon, Delordson, Kassam, Jamila, Lancoma-Malcolm, Ivone, Matharu, Maninderpal, May, Peter, Mitchelmore, Oliver, Newman, Tabitha, Patel, Mital, Pheby, Jane, Pinzuti, Irene, Prime, Zoe, Prysyazhna, Oleksandra, Shiel, Julian, Taylor, Melanie, Tierney, Carey, Wood, Suzanne, Zak, Anne, Zongo, Olivier, Forsey, Miranda, Nicholson, Anne, Riches, Joanne, Vertue, Mark, Wasson, Christopher, Finn, Stephanie, Green, Jackie, Collins, Erin, King, Bernadette, Grauslyte, Lina, Hussain, Musarat, Pogreban, Tatiana, Rosaroso, Lace, Salciute, Erika, Franke, George, Wong, Joanna, George, Aparna, Akeroyd, Louise, Bano, Shereen, Bromley, Matt, Gurr, Lucy, Lawton, Tom, Morgan, Jame, Sellick, Kirsten, Warren, Deborah, Wilkinson, Brian, Mcgowan, Janet, Ledgard, Camilla, Stacey, Amelia, Pye, Kate, Bellwood, Ruth, Bentley, Michael, Loosley, Ronda, Mcguinness, Heather, Tench, Helen, Wolf-Roberts, Rebecca, Gibson, Sian, Lyle, Amanda, Mcneela, Fiona, Radhakrishnan, Jayachandran, Hughes, Alistair, Ali, Asifa, Brady, Megan, Dale, Sam, Dance, Annalisa, Gledhill, Lisa, Greig, Jill, Hanson, Kathryn, Holdroyd, Kelly, Home, Marie, Kelly, Diane, Kitson, Ro, Matapure, Lear, Melia, Deborah, Mellor, Samantha, Nortcliffe, Tonicha, Pinnell, Jez, Robinson, Matthew, Shaw, Lisa, Shaw, Ryan, Thomis, Lesley, Wilson, Alison, Wood, Tracy, Bayo, Lee-Ann, Merwaha, Ekta, Ishaq, Tahira, Hanley, Sarah, Antcliffe, David, Banach, Dorota, Brett, Stephen, Coghlan, Phoebe, Fernandez, Ziortza, Gordon, Anthony, Rojo, Roceld, Arias, Sonia Sousa, Templeton, Maie, Jha, Rajeev, Krishnamurthy, Vinodh, Lim, Lai, Bi, Rehana, Scholefield, Barney, Ashton, Lydia, Williams, Alison, Cheyne, Claire, Saunderson, Anne, Allan, Angela, Anderson, Felicity, Kaye, Callum, Liew, Jade, Medhora, Jasmine, Scott, Teresa, Trumper, Erin, Botello, Adriana, Polgarova, Petra, Stroud, Katerina, Meaney, Eoghan, Jones, Megan, Ng, Anthony, Agrawal, Shruti, Pathan, Nazima, White, Deborah, Daubney, Esther, Elston, Kay, Parker, Robert, Reddy, Amie, Turner-Bone, Ian, Wilding, Laura, Harding, Peter, Jacob, Reni, Jones, Cathy, Denmade, Craig, Croft, Maria, White, Ian, Lim, Li, Griffin, Denise, Muchenje, Nycola, Mupudzi, Mcdonald, Partridge, Richard, Conyngham, Jo-Anna, Thomas, Rachel, Wright, Mary, Corral, Maria Alvarez, Bastion, Victoria, Clarke, Daphene, David, Beena, Kent, Harriet, Lorusso, Rachel, Lubimbi, Gamu, Murdoch, Sophie, Penacerrada, Melchizedek, Thomas, Alastair, Valentine, Jennifer, Vochin, Ana, Wulandari, Retno, Djeugam, Brice, Dawson, Joy, Garrioch, Sweyn, Tolson, Melanie, Aldridge, Jonathan, de Almeida Martins, Laura Gome, Carungcong, Jaime, Beavis, Sarah, Dale, Katie, Gascoyne, Rachel, Hawes, Joanne, Pritchard, Kelly, Stevenson, Lesley, Whileman, Amanda, Cowley, Anne, Highgate, Judith, Crawley, Rikki, Crew, Abigail, Cunningham, Mishell, Daniels, Allison, Harrison, Laura, Hope, Susan, Inweregbu, Ken, Jones, Sian, Lancaster, Nicola, Matthews, Jamie, Nicholson, Alice, Wray, Gemma, Benham, Leonie, Bradshaw, Zena, Brown, Joanna, Caswell, Melanie, Melling, Sarah, Preston, Stephen, Slawson, Nicola, Stoddard, Emma, Warden, Scott, Combes, Edward, Joefield, Teishel, Monnery, Sonja, Beech, Valerie, Trotman, Sallyanne, Hopkins, Bridget, Scriven, Jame, Thrasyvoulou, Laura, Willis, Heather, Anderson, Susan, Birch, Janine, Collins, Emma, Hammerton, Kate, O’Leary, Ryan, Abernathy, Caroline, Foster, Louise, Gratrix, Andrew, Martinson, Vicky, Parkinson, Priyai, Stones, Elizabeth, Carbral-Ortega, Llucia, Kapoor, Ritoo, Loader, David, Castle, Karen, Brandwood, Craig, Smith, Lara, Clark, Richard, Birchall, Katie, Kolakaluri, Laurel, Baines, Deborah, Sukumaran, Anila, Mapfunde, Isheunesu, Meredith, Megan, Morris, Lucy, Ryan, Lucy, Clark, Amy, Sampson, Julia, Peters, Cecilia, Dent, Martin, Langley, Margaret, Ashraf, Saima, Wei, Shuying, Andrew, Angela, Chablani, Manish, Kirkby, Amy, Netherton, Kimberley, Bates, Michelle, Dasgin, Jo, Gill, Jaspret, Nilsson, Annette, Apetri, Elena, Basikolo, Cathrine, Blackledge, Bethan, Catlow, Laura, Charles, Bethan, Doonan, Reece, Harris, Jade, Harvey, Alice, Horner, Daniel, Knowles, Karen, Lee, Stephanie, Lomas, Diane, Lyons, Chloe, Marsden, Tracy, Mclaughlan, Danielle, Mcmorrow, Liam, Pendlebury, Jessica, Perez, Jane, Poulaka, Maria, Proudfoot, Nicola, Slaughter, Melanie, Slevin, Kathryn, Thomas, Vicky, Walker, Danielle, Michael, Angiy, Collis, Matthew, Clark, Martyn, Coulding, Martina, Jude, Edward, Mccormick, Jacqueline, Mercer, Oliver, Potla, Darsh, Rehman, Hafiz, Savill, Heather, Turner, Victoria, Davey, Miriam, Golden, David, Seaman, Rebecca, Hunt, Jodie, Dearden, Joy, Dobson, Emma, Mulcahy, Michelle, Munt, Sheila, O’Connor, Grainne, Philbin, Jennifer, Rishton, Chloe, Tully, Redmond, Winnard, Sarah, Cagova, Lenka, Fofano, Adama, Garner, Lucie, Holcombe, Helen, Mepham, Sue, Mitchell, Alice Michael, Mwaura, Lucy, Praman, K., Vuylsteke, Alain, Zamikula, Julie, Bercades, Georgia, Brealey, David, Hass, Ingrid, Maccallum, Niall, Martir, Glady, Raith, Eamon, Reyes, Anna, Smyth, Deborah, Taylor, Abigail, Hughes, Rachel Anne, Thomas, Helen, Rees, Alun, Duskova, Michaela, Phipps, Janet, Brooks, Suzanne, Edwards, Michelle, Alexander, Peter, Allen, Schvearn, Bradley-Potts, Joanne, Brantwood, Craig, Egan, Jasmine, Felton, Timothy, Padden, Grace, Ward, Luke, Moss, Stuart, Glasgow, Susannah, Beesley, Kate, Board, Sarah, Kubisz-Pudelko, Agnieszka, Lewis, Alison, Perry, Je, Pippard, Lucy, Wood, Di, Buckley, Clare, Brown, Alison, Gregory, Jane, O’Connell, Susan, Smith, Tim, Belagodu, Zakaula, Fuller, Bridget, Gherman, Anca, Olufuwa, Olumide, Paramsothy, Remi, Stuart, Carmel, Oakley, Naomi, Kamundi, Charlotte, Tyl, David, Collins, Katy, Silva, Pedro, Taylor, June, King, Laura, Coates, Charlotte, Crowley, Maria, Wakefield, Phillipa, Beadle, Jane, Johnson, Laura, Sargeant, Janet, Anderson, Madeleine, Jardine, Catherine, Williams, Dewi, Parris, Victoria, Quaid, Sheena, Watson, Ekaterina, Melville, Julie, Naisbitt, Jay, Joseph, Rosane, Lazo, Maria, Walton, Olivia, Neal, Alan, Hill, Michaela, Kannan, Thogulava, Wild, Laura, Allan, Elizabeth, Darlington, Kate, Davies, Ffyon, Easton, Jack, Kumar, Sumit, Lean, Richard, Menzies, Daniel, Pugh, Richard, Qiu, Xinyi, Davies, Llino, Williams, Hannah, Scanlon, Jeremy, Davies, Gwyneth, Mackay, Callum, Lewis, Joannne, Rees, Stephanie, Coetzee, Samantha, Gales, Alistair, Raj, Meena, Sell, Craig, Langton, Helen, Watters, Malcolm, Novis, Catherine, Arbane, Gill, Bociek, Aneta, Campos, Sara, Grau, Neu, Jones, Tim Owen, Lim, Rosario, Marotti, Martina, Whitton, Christopher, Barron, Anthony, Collins, Ciara, Kaul, Sundeep, Passmore, Heather, Prendergast, Claire, Reed, Anna, Rogers, Paula, Shokkar, Rajvinder, Woodruff, Meriel, Middleton, Hayley, Polgar, Oliver, Nolan, Claire, Thwaites, Vicky, Mahay, Kanta, Sri-Chandana, Chunda, Scherewode, Joslan, Stephenson, Lorraine, Marsh, Sarah, Bancroft, Hollie, Bellamy, Mary, Carmody, Margaret, Daglish, Jacqueline, Moore, Faye, Rhodes, Joanne, Sangombe, Mirriam, Kadiri, Salma, Ayers, Amanda, Harrison, Wendy, North, Julie, Cavazza, Anna, Cockrell, Maeve, Corcoran, Eleanor, Depante, Maria, Finney, Clare, Jerome, Ellen, Mcphail, Mark, Nayak, Monalisa, Noble, Harriet, O’Reilly, Kevin, Pappa, Evita, Saha, Rohit, Saha, Sian, Smith, John, Knighton, Abigail, Gill, Mandy, Paul, Paul, Ratnam, Valli, Shelton, Sarah, Wynter, Inez, Baptista, David, Crowe, Rebecca, Fernandes, Rita, Herdman-Grant, Rosaleen, Joseph, Anna, Loveridge, Adam, Mckenley, India, Morino, Eriko, Naranjo, Andre, Simms, Richard, Sollesta, Kathryn, Swain, Andrew, Venkatesh, Harish, Khera, Jacyntha, Fox, Jonathan, Barber, Russell, Hewitt, Claire, Hilldrith, Annette, Jackson-Lawrence, Karen, Shepardson, Sarah, Wills, Maryanne, Butler, Susan, Tavares, Silvia, Cunningham, Amy, Hindale, Julia, Arif, Sarwat, George, Linsha, Twiss, Sophie, Wright, David, Holland, Maureen, Keenan, Natalie, Lyons, Marc, Wassall, Helen, Marsh, Chri, Mahenthran, Mervin, Carter, Emma, Kong, Thoma, Adanini, Oluronke, Bhatia, Nikhil, Msiska, Maine, Mew, Louise, Mwaura, Esther, Williams, Felicity, Wren, Lynn, Sutherland, Sara-Beth, Battle, Ceri, Brinkworth, Elaine, Harford, Rachel, Murphy, Carl, Newey, Luke, Rees, Tabitha, Williams, Marie, Arnold, Sophie, Hardy, John, Houlden, Henry, Moncur, Eleanor, Tariq, Ambreen, Tucci, Arianna, Convery, Karen, Fottrell-Gould, Deirdre, Hudig, Lisa, Keshet-Price, Jocelyn, Randell, Georgina, Stammers, Katie, Abdelrazik, Marwa, Bakthavatsalam, Dhanalakshmi, Elhassan, Munzir, Ganesan, Arunkumar, Haldeos, Anne, Moreno-Cuesta, Jeronimo, Purohit, Dharam, Vincent, Rachel, Xavier, Kugan, Rohit, Kumar, Alasdair, Frater, Saleem, Malik, David, Carter, Jenkins, Samuel, Lamond, Zoe, Wall, Alanna, Reynolds, Jessica, Campbell, Helen, Thompsom, Maria, Dodds, Steve, Duffy, Stacey, Butcher, Deborah, O’Sullivan, Susie, Butterworth-Cowin, Nicola, Deacon, Bethan, Hibbert, Meg, Pothecary, Carla, Tetla, Dariusz, Woodford, Christopher, Durga, Latha, Kennard-Holden, Gareth, de Gordoa, Laura Ortiz-Ruiz, Peasgood, Emily, Phillips, Claire, Skinner, Denise, Gaylard, Jane, Mullan, Dee, Newman, Julie, Davies, Ellie, Roche, Lisa, Sathe, Sonia, Brimfield, Lutece, Daly, Zoe, Pogson, David, Rose, Steve, Collins, Amy, Khaliq, Waqa, Gude, Estefania Treu, Allen, Louise, Beranova, Eva, Crisp, Nikki, Deery, Joanne, Hazelton, Tracy, Knight, Alicia, Price, Carly, Tilbey, Sorrell, Turki, Salah, Turney, Sharon, Giles, Julian, Booth, Simon, Bell, Gillian, English, Katy, Katary, Amro, Wilcox, Louise, Campbell, Rachael, Clarke, Noreen, Whiteside, Jonathan, Mascarenhas, Mairi, Donaldson, Avril, Matheson, Joanna, Barrett, Fiona, O’Hara, Marianne, O’Keefe, Laura, Bradley, Clare, Collier, Dawn, Walker, Rachel, Maynard, Victoria, Patel, Tahera, Smith, Matthew, Kazi, Aayesha, Hartley, Janice, Dykes, Joseph, Hijazi, Muhammad, Keith, Sarah, Khan, Meherunnisa, Ryan-Smith, Janet, Springle, Philippa, Thomas, Jacqueline, Truman, Nick, Saad, Samuel, Coleman, Dabheoc, Fine, Christopher, Matt, Roseanna, Gay, Bethan, Dalziel, Jack, Ali, Syamlan, Goodchild, Drew, Harling, Rhiannan, Bhatterjee, Ravi, Goddard, Wendy, Davison, Chloe, Duberly, Stephen, Hargreaves, Jeanette, Bolton, Rachel, Verlander, Mark, Williams, Alexandra, Blackman, Helen, Creagh-Brown, Ben, Donlon, Sinead, Michalak-Glinska, Natalia, Mtuwa, Sheila, Pristopan, Veronika, Salberg, Armorel, Smith, Eleanor, Stone, Sarah, Piercy, Charle, Verula, Jerik, Burda, Dorota, Montaser, Rugia, Harden, Lesley, Mayangao, Irving, Marriott, Cheryl, Bradley, Paul, Harris, Celia, Cooper, Joshua, Finch, Cheryl, Liderth, Sarah, Quinn, Alison, Waddington, Natalia, Fidler, Katy, Tagliavini, Emma, Donnelly, Kevin, Abel, Lynn, Brett, Michael, Digby, Brian, Gemmell, Lisa, Hornsby, Jame, Macgoey, Patrick, O’Neil, Pauline, Price, Richard, Rodden, Natalie, Rooney, Kevin, Sundaram, Radha, Thomson, Nicola, Flanagan, Rebecca, Hughes, Gareth, Latham, Scott, Mckenna, Emma, Anderson, Jennifer, Hull, Robert, Rhead, Kat, Branney, Debbie, Frankham, Jordan, Pitts, Sally, White, Nigel, Cristiano, Daniele, Dormand, Natalie, Farzad, Zohreh, Gummadi, Mahitha, Liyanage, Kamal, Patel, Brijesh V., Salmi, Sara, Sloane, Geraldine, Varghese, Mathew, Zborowski, Anelise C., Bean, Sarah, Burt, Karen, Spivey, Michael, Eastgate-Jackson, Christine, Filipe, Helder, Martin, Daniel, Maharajh, Amitaa, Garcia, Sara Mingo, De Neef, Mark, Lynch, Ceri, Howe, Gwenllian Sera, Singh, Jayaprakash, Turner, Keri, Ellis, Hannah, Stroud, Natalie, Cherian, Shiney, Cutler, Sean, Heron, Anne Emma, Roynon-Reed, Anna, Williams, Gemma, Richards, Owen, Cheema, Yusuf, Ahmad, Norfaizan, Barker, Joann, Bauchmuller, Kri, Bird, Sarah, Cawthron, Kay, Harrington, Kate, Jackson, Yvonne, Kibutu, Faith, Lenagh, Becky, Masuko, Shamiso, Raithatha, Ajay, Wiles, Matthew, Willson, Jayne, Newell, Helen, Lye, Alison, Nwafor, Lorenza, Jarman, Claire, Rowland-Jones, Sarah, Foote, David, Cole, Joby, Thompson, Roger, Watson, Jame, Hesseldon, Lisa, Macharia, Irene, Chetam, Luke, Smith, Jacqui, Ford, Amber, Anderson, Samantha, Birchall, Kathryn, Housley, Kay, Walker, Sara, Milner, Leanne, Hanratty, Helena, Trower, Helen, Phillips, Patrick, Oxspring, Simon, Donne, Ben, Bevan, Emily, Martin, Jane, Trodd, Dawn, Watson, Geoff, Brown, Caroline Wrey, Bunni, Lara, Jennings, Claire, Latif, Monica, Marshall, Rebecca, Subramanian, Gayathri, Bandla, Nageswar, Gellamucho, Minnie, Davies, Michelle, Thompson, Christopher, Trim, Fiona, Eapen, Beena, Ahmed, Cecilia, Baines, Balvinder, Clamp, Sarah, Colley, Julie, Haq, Risna, Hayes, Anne, Hulme, Jonathan, Hussain, Samia, Joseph, Sibet, Kumar, Rita, Maqsood, Zahira, Purewal, Manjit, Chandler, Ben, Elliott, Kerry, Mallinson, Janine, Turnbull, Alison, Dent, Kathy, Horsley, Elizabeth, Akhtar, Muhmmad Nauman, Pearson, Sandra, Potoczna, Dorota, Spencer, Sue, Blakemore, Hayley, Borislavova, Borislava, Faulkner, Beverley, Gendall, Emma, Goff, Elizabeth, Hayes, Kati, Thomas, Matt, Worner, Ruth, Smith, Kerry, Stephens, Deanna, Delgado, Carlos Castro, Dawson, Deborah, Ding, Lijun, Durrant, Georgia, Ezeobu, Obiageri, Farnell-Ward, Sarah, Harrison, Abiola, Kanu, Rebecca, Leaver, Susannah, Maccacari, Elena, Manna, Soumendu, Saluzzio, Romina Peperman, Queiroz, Joana, Samakomva, Tinashe, Sicat, Christine, Texeira, Joana, Da Gloria, Edna Fernande, Lisboa, Ana, Rawlins, John, Mathew, Jisha, Kinch, Ashley, Hurt, William Jame, Shah, Nirav, Clark, Victoria, Thanasi, Maria, Yun, Nikki, Patel, Kamal, Crickmore, Vikki, Debreceni, Gabor, Wilkins, Joy, Nicol, Liz, Burn, Iona, Hambrook, Geraldine, Manso, Katarina, Penn, Ruth, Shanmugasundaram, Pradeep, Tebbutt, Julie, Thornton, Danielle, Rostron, Anthony, Roy, Alistair, Woods, Lindsey, Cornell, Sarah, Wakinshaw, Fiona, Rogerson, Kimberley, Jarmain, Jordan, Anderson, Peter, Archer, Katie, Austin, Karen, Davis, Caroline, Durie, Alison, Kelsall, Olivia, Thrush, Jessica, Vigurs, Charlie, Wood, Hannah-Louise, Tranter, Helen, Harrison, Alison, Cowley, Nichola, Mcalindon, Michael, Digby, Stephen, Low, Emma, Morgan, Aled, Cother, Naiara, Rankin, Tobia, Clayton, Sarah, Mccurdy, Alex, Allibone, Suzanne, Mary-Genetu, Roman, Patel, Amit, Mac, Ainhi, Murphy, Anthony, Mahjoob, Parisa, Nazari, Roonak, Worsley, Lucy, Fagan, Andrew, Mohamed Ali, Inthakab Ali, Beaumont, Karen, Blunt, Mark, Coton, Zoe, Curgenven, Hollie, Elsaadany, Mohamed, Fernandes, Kay, Ally, Sameena Mohamed, Rangarajan, Harini, Sarathy, Varun, Selvanayagam, Sivarupan, Vedage, Dave, White, Matthew, Fernandez-Roman, Jaime, Hamilton, David O., Johnson, Emily, Johnston, Brian, Martinez, Maria Lopez, Mulla, Suleman, Shaw, David, Waite, Alicia A. C., Waugh, Victoria, Welters, Ingeborg D., Williams, Karen, Bemand, Thoma, Black, Ethel, Rosa, Arnold Dela, Howle, Ryan, Jhanji, Shaman, Baikady, Ravishankar Rao, Tatham, Kate Colette, Thomas, Benjamin, Halkes, Matthew, Mercer, Pauline, Thornton, Lorraine, West, Joe, Baird, Tracy, Ruddy, Jim, Reece-Anthony, Rosie, Birt, Mark, Cowton, Amanda, Kay, Andrea, Kent, Melanie, Potts, Kathryn, Wilkinson, Ami, Naylor, Suzanne, Brown, Ellen, Clark, Michele, Purvis, Sarah, Cole, Jade, Davies, Rhy, Duffin, Donna, Hill, Helen, Player, Ben, Thomas, Emma, Williams, Angharad, Beith, Claire Marie, Black, Karen, Clements, Suzanne, Morrison, Alan, Strachan, Dominic, Taylor, Margaret, Clarkson, Michelle, D’Sylva, Stuart, Norman, Kathryn, Coventry, Tina, Fowler, Susan, Mcgregor, Amanda, Brady, Ailbhe, Chan, Rebekah, Mcivor, Shane, Prady, Helena, Whittle, Helen, Mathew, Bijoy, Clapham, Melanie, Harper, Rosemary, Poultney, Una, Rice, Polly, Mutch, Rachel, Baird, Yolanda, Butler, Aaron, Chadbourn, Indra, Folkes, Linda, Fox, Heather, Gardner, Amy, Gomez, Raquel, Hobden, Gillian, King, Kirsten, Margarson, Michael, Martindale, Tim, Meadows, Emma, Raynard, Dana, Thirlwall, Yvette, Helm, David, Margalef, Jordi, Greer, Sandra, Shuker, Karen, Smuts, Sara, Duffield, Joseph, Smith, Oliver, Mallon, Lewi, Claire, Watkin, Birkinshaw, Isobel, Carter, Joseph, Howard, Kate, Ingham, Joanne, Joy, Rosie, Pearson, Harriet, Roche, Samantha, Scott, Zoe, Knights, Ellen, Price, Alicia, Thomas, Alice, Thorpe, Chri, Abraheem, Azmerelda, Bamford, Peter, Cawley, Kathryn, Dunmore, Charlie, Faulkner, Maria, Girach, Rumanah, Jeffrey, Helen, Jones, Rhianna, London, Emily, Nagra, Imrun, Nasir, Farah, Sainsbury, Hannah, Smedley, Clare, Khade, Reena, Sundar, Ashok, Tsinaslanidis, George, Behan, Teresa, Burnett, Caroline, Hatton, Jonathan, Heeney, Elaine, Mitra, Atideb, Newton, Maria, Pollard, Rachel, Stead, Rachael, Birch, Jenny, Bough, Laura, Goodsell, Josie, Tutton, Rebecca, Williams, Patricia, Williams, Sarah, Winter-Goodwin, Barbara, Auld, Fiona, Donnachie, Joanne, Edmond, Ian, Prentice, Lynn, Runciman, Nikole, Salutous, Dario, Symon, Lesley, Todd, Anne, Turner, Patricia, Short, Abigail, Sweeney, Laura, Murdoch, Euan, Senaratne, Dhaneesha, Burns, Karen, Higham, Andrew, Anderson, Taya, Hawcutt, Dan, O’Malley, Laura, Rad, Laura, Rogers, Naomi, Saunderson, Paula, Allison, Kathryn Sian, Afolabi, Deborah, Whitbread, Jennifer, Jones, Dawn, Dore, Rachael, Lankester, Liana, Nikitas, Nikita, Wells, Colin, Stowe, Bethan, Spencer, Kayleigh, Cathcart, Susanne, Duffy, Katharine, Puxty, Alex, Puxty, Kathryn, Turner, Lynne, Ireland, Jane, Semple, Gary, Barry, Peter, Hilltout, Paula, Evitts, Jayne, Tyler, Amanda, Waldron, Joanne, Irvine, Val, Shelley, Benjamin, Akinkugbe, Olugbenga, Bamford, Alasdair, Beech, Emily, Belfield, Holly, Bell, Michael, Davies, Charlene, Jones, Gareth A. L., Mchugh, Tara, Meghari, Hamza, O’Neill, Lauran, Peters, Mark J., Ray, Samiran, Tomas, Ana Luisa, Gorman, Claire, Gupta, Abhinav, Timlick, Elizabeth, Brady, Rebecca, Bonner, Stephen, Hugill, Keith, Jones, Jessica, Liggett, Steven, Bashyal, Archana, Davidson, Neil, Hutton, Paula, Mckechnie, Stuart, Wilson, Jean, Flint, Neil, Rekha, Patel, Hales, Dawn, Cruz, Carina, Gopal, Shameer, Harris, Nichola, Lake, Victoria, Metherell, Stella, Radford, Elizabeth, Clement, Ian, Patel, Bijal, Gulati, A., Hays, Carole, Webster, K., Hudson, Anne, Webster, Andrea, Stephenson, Elaine, Mccormack, Louise, Slater, Victoria, Nixon, Rachel, Hanson, Helen, Fearby, Maggie, Kelly, Sinead, Bridgett, Victoria, Robinson, Philip, Almaden-Boyle, Christine, Austin, Pauline, Cabrelli, Louise, Cole, Stephen, Casey, Matt, Chapman, Susan, Whyte, Clare, Brayne, Adam, Fisher, Emma, Hunt, Jane, Jackson, Peter, Kaye, Duncan, Love, Nichola, Parkin, Juliet, Tuckey, Victoria, van Koutrik, Lynne, Carter, Sasha, Andrew, Benedict, Findlay, Louise, Adams, Katie, Bruce, Michelle, Connolly, Karen, Duncan, Tracy, T. -Michael, Helen, Lindergard, Gabriella, Hey, Samuel, Fox, Claire, Alfonso, Jordan, Durrans, Laura Jayne, Guerin, Jacinta, Hruska, Martin, Eltayeb, Ayaa, Lamb, Thoma, Hodgkiss, Tracey, Cooper, Lisa, Rothwell, Joanne, Dennis, Catherine, Mcgregor, Alastair, Srikaran, Sinduya, Sukha, Anisha, Davies, Kim, O’Brien, Linda, Omar, Zohra, Perkins, Emma, Lewis, Tracy, Sutherland, Isobel, Brooke, Hollie, Buckley, Sarah, Suarez, Jose Cebrian, Charlesworth, Ruth, Hansson, Karen, Norris, John, Poole, Alice, Rose, Alastair, Sandhu, Rajdeep, Sloan, Brendan, Smithson, Elizabeth, Thirumaran, Muthu, Wagstaff, Veronica, Metcalfe, Alexandra, Camsooksai, Julie, Humphrey, Charlotte, Jenkins, Sarah, Wadams, Beverley, Death, Yasmin, Adams, Colene, Agasou, Anita, Arden, Tracie, Bowes, Amy, Boyle, Pauline, Beekes, Mandy, Button, Heather, Capps, Nigel, Carnahan, Mandy, Carter, Anne, Childs, Danielle, Donaldson, Denise, Hard, Kelly, Hurford, Fran, Hussain, Yasmin, Javaid, Ayesha, Jones, Jame, Jose, Sanal, Leigh, Michael, Martin, Terry, Millward, Helen, Motherwell, Nichola, Rikunenko, Rachel, Stickley, Jo, Summers, Julie, Ting, Louise, Tivenan, Helen, Tonks, Louise, Wilcox, Rebecca, Bokhari, Maria, Lucas, Rachael, Mccormick, Wendy, Ritzema, Jenny, Sanderson, Amanda, Wild, Helen, Baxter, Nicola, Henderson, Steven, Kennedy-Hay, Sophie, Mcparland, Christopher, Rooney, Laura, Sim, Malcolm, Mccreath, Gordan, Brunton, Mark, Caterson, Je, Coles, Holly, Frise, Matthew, Rai, Sabi Gurung, Keating, Liza, Tilney, Emma, Bartley, Shauna, Bhuie, Parminder, Downes, Charlotte, Holding, Kathleen, Riches, Katie, Hilton, Mary, Hayman, Mel, Subramanian, Deepak, Daniel, Priya, Zitter, Letizia, Benyon, Sarah, Marriott, Suzie, Park, Linda, Keenan, Samantha, Gordon, Elizabeth, Quinn, Helen, Baines, Kizzy, Andrew, Gillian, Barclay, Lucy, Callaghan, Marie, Clark, Sarah, Hope, Dave, Marshall, Lucy, Mcculloch, Corrienne, Briton, Kate, Singleton, Jo, Birch, Sophie, Simpson, Kerry, Craig, Jayne, Demetriou, Carrie, Eckbad, Charlotte, Hierons, Sarah, Howie, Lucy, Mitchard, Sarah, Ramos, Lidia, Serrano-Ruiz, Alfredo, White, Katie, Kelly, Fiona, Amin, Vishal, Anastasescu, Elena, Anumakonda, Vikram, Karthik, Komala, Kausar, Rizwana, Reid, Karen, Smith, Jacqueline, Imeson-Wood, Janet, Bellini, Arianna, Bryant, Jade, Mayer, Anton, Pickard, Amy, Roe, Nichola, Sowter, Jason, Howlett, Alex, Criste, Kristine, Cusack, Rebecca, Golder, Kim, Golding, Hannah, Jones, Oliver, Leggett, Samantha, Male, Michelle, Marani, Martyna, Prager, Kirsty, Williams, Toran, Roberts, Belinda, Salmon, Karen, Gondo, Prisca, Hadebe, B., Kayani, Abdul, Masunda, Bridgett, Ahmed, Ashar, Morris, Anna, Jakkula, Sriniva, Long, Kate, Whiteley, Simon, Wilby, Elizabeth, Ogg, Bethan, Moultrie, Sam, Odam, M., Bewley, Jeremy, Garland, Zoe, Grimmer, Lisa, Gumbrill, Bethany, Johnson, Rebekah, Sweet, Katie, Webster, Denise, Efford, Georgia, Bennett, Sara, Goodwin, Emma, Jackson, Matthew, Kent, Alissa, Tibke, Clare, Woodyatt, Wiesia, Zaki, Ahmed, Daniel, Amelia, Finn, Joanne, Saha, Rajnish, Bremmer, Pamela, Allan, J., Geary, T., Houston, Gordon, Meikle, A., O’Brien, P., Bell, Dina, Boyle, Rosalind, Douglas, Katie, Glass, Lynn, Lee, Emma, Lennon, Liz, Rattray, Austin, Charnock, Rob, Mcfarland, Denise, Cosgrove, Denise, Attwood, Ben, Parsons, Penny, Carmody, Siobhain, Oblak, Metod, Popescu, Monica, Thankachen, Mini, Baruah, Rosie, Morris, Sheila, Ferguson, Susie, Shepherd, Amy, Altabaibeh, Abdelhakim, Alvaro, Ana, Gilbert, Kayleigh, Ma, Louise, Mostoles, Loreta, Parmar, Chetan, Simpson, Kathryn, Jetha, Champa, Booker, Lauren, Pratley, Anezka, Cosier, Tracey, Millen, Gemma, Schumacher, Natasha, Weston, Heather, Rand, Jame, Alex, Beatrice, Bach, Benjamin, Barclay, Wendy S., Bogaert, Debby, Chand, Meera, Cooke, Graham S., Docherty, Annemarie B., Dunning, Jake, da Silva Filipe, Ana, Fletcher, Tom, Green, Christoper A., Harrison, Ewen M., Hiscox, Julian A., Ijaz, Samreen, Khoo, Saye, Lim, Wei Shen, Mentzer, Alexander J., Merson, Laura, Noursadeghi, Mahdad, Moore, Shona C., Palmarini, Massimo, Paxton, William A., Pollakis, Georgio, Price, Nichola, Rambaut, Andrew, Robertson, David L., Sancho-Shimizu, Vanessa, Scott, Janet T., de Silva, Thushan, Sigfrid, Louise, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Tedder, Richard S., Thomson, Emma C., Roger Thompson, A. A., Thwaites, Ryan S., Turtle, Lance C. W., Gupta, Rishi K., Palmieri, Carlo, Swann, Olivia V., Zambon, Maria, Dumas, Marc-Emmanuel, Griffin, Julian L., Takats, Zoltan, Chechi, Kanta, Andrikopoulos, Petro, Osagie, Anthonia, Olanipekun, Michael, Liggi, Sonia, Lewis, Matthew R., Correia, Gonçalo dos Santo, Sands, Caroline J., Takis, Panteleimon, Maslen, Lynn, Greenhalf, William, Shaw, Victoria, Mcdonald, Sarah E., Keating, Seán, Ahmed, Katie A., Armstrong, Jane A., Ashworth, Milton, Asiimwe, Innocent G., Bakshi, Siddharth, Barlow, Samantha L., Booth, Laura, Brennan, Benjamin, Bullock, Katie, Catterall, Benjamin W. A., Clark, Jordan J., Clarke, Emily A., Cooper, Louise, Cox, Helen, Davis, Christopher, Dincarslan, Oslem, Dunn, Chri, Dyer, Philip, Elliott, Angela, Evans, Anthony, Finch, Lorna, Fisher, Lewis W. S., Foster, Terry, Garcia-Dorival, Isabel, Gunning, Philip, Hartley, Catherine, Jensen, Rebecca L., Jones, Christopher B., Jones, Trevor R., Khandaker, Shadia, King, Katharine, Kiy, Robyn T., Koukorava, Chrysa, Lake, Annette, Lant, Suzannah, Latawiec, Diane, Lavelle-Langham, Lara, Lefteri, Daniella, Lett, Lauren, Livoti, Lucia A., Mancini, Maria, Mcdonald, Sarah, Mcevoy, Laurence, Mclauchlan, John, Metelmann, Soeren, Miah, Nahida S., Middleton, Joanna, Mitchell, Joyce, Murphy, Ellen G., Penrice-Randal, Rebekah, Pilgrim, Jack, Prince, Tessa, Reynolds, Will, Ridley, P. Matthew, Sales, Debby, Shaw, Victoria E., Shears, Rebecca K., Small, Benjamin, Subramaniam, Krishanthi S., Szemiel, Agnieska, Taggart, Aislynn, Tanianis-Hughes, Jolanta, Thomas, Jordan, Trochu, Erwan, van Tonder, Libby, Wilcock, Eve, Zhang, J. Eunice, Flaherty, Lisa, Maziere, Nicole, Cass, Emily, Carracedo, Alejandra Doce, Carlucci, Nicola, Holmes, Anthony, Massey, Hannah, Murphy, Lee, Wrobel, Nicola, Mccafferty, Sarah, Morrice, Kirstie, Maclean, Alan, Armstrong, Ruth, Boz, Ceilia, Brown, Adam, Coutts, Audrey, Cullum, Louise, Day, Nicky, Donnelly, Lorna, Duncan, Esther, Fawkes, Angie, Finernan, Paul, Gilchrist, Tammy, Golightly, Ailsa, Hafezi, Katarzyna, Law, Dawn, Law, Rachel, Law, Sarah, Macgillivray, Louise, Mal, Hanning, Mcmaster, Ellie, Meikle, Jen, Oosthuyzen, Wilna, Paterson, Trevor, Stenhouse, Andrew, Swets, Maaike, Szoor-McElhinney, Helen, Taneski, Filip, Wackett, Tony, Ward, Mairi, Weaver, Jane, Coyle, Judy, Gallagher, Bernadette, Lidstone-Scott, Rebecca, Hamilton, Debbie, Schon, Katherine, Furlong, Anita, Biggs, Heather, Griffiths, Fiona, Andrews, Eleanor, Brickell, Kathy, Smyth, Michelle, Murphy, Lorna, Carson, Gail, Hardwick, Hayley, Donohue, Chloe, Pérez-Tur, Jordi [0000-0002-9111-1712], Martín, Javier [0000-0002-2202-0622], Institute for Molecular Medicine Finland [Helsinki] (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki-University of Helsinki, Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], Massachusetts General Hospital [Boston], A list of authors and their affiliations appears in the Supplementary Information, Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsingin yliopisto = Helsingfors universitet = University of Helsinki, ANR-20-CO11-0001,AABIFNCOV,Bases génétiques et immunologiques des auto-anticorps contre les interférons de type I prédisposant aux formes sévères de COVID-19.(2020), ANR-20-COVI-0003,GENCOVID,Identification des défauts monogéniques de l'immunité responsables des formes sévères de COVID-19 chez les patients précédemment en bonne santé(2020), ANR-21-COVR-0039,GenMIS-C,Recherche des Déficits immunitaires innées monogéniques prédisposant au syndrome inflammatoire multisystémique chez l'enfant.(2021), UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (MGD) Service de gastro-entérologie, Niemi, M, Karjalainen, J, Liao, R, Neale, B, Daly, M, Ganna, A, Pathak, G, Andrews, S, Kanai, M, Veerapen, K, Fernandez-Cadenas, I, Schulte, E, Striano, P, Marttila, M, Minica, C, Marouli, E, Karim, M, Wendt, F, Savage, J, Sloofman, L, Butler-Laporte, G, Kim, H, Kanoni, S, Okada, Y, Byun, J, Han, Y, Uddin, M, Smith, G, Willer, C, Buxbaum, J, Mehtonen, J, Finucane, H, Cordioli, M, Martin, A, Zhou, W, Pasaniuc, B, Julienne, H, Aschard, H, Shi, H, Yengo, L, Polimanti, R, Ghoussaini, M, Schwartzentruber, J, Dunham, I, Chwialkowska, K, Francescatto, M, Trankiem, A, Balaconis, M, Davis, L, Lee, S, Priest, J, Renieri, A, Sankaran, V, van Heel, D, Deelen, P, Richards, J, Nakanishi, T, Biesecker, L, Kerchberger, V, Baillie, J, Mari, F, Bernasconi, A, Baillie, S, Canakoglu, A, Wolford, B, Faucon, A, Dutta, A, Schurmann, C, Harry, E, Birney, E, Nguyen, H, Nasir, J, Kaunisto, M, Solomonson, M, Dueker, N, Vadgama, N, Limou, S, Rahmouni, S, Mbarek, H, Darwish, D, Albertos, R, Pérez-Tur, J, Li, R, Folkersen, L, Moltke, I, Koelling, N, Teumer, A, Kousathanas, A, Utrilla, A, Verdugo, R, Zárate, R, Medina-Gómez, C, Gómez-Cabrero, D, Carnero-Montoro, E, Cadilla, C, Moreno-Estrada, A, Garmendia, A, Moya, L, Sedaghati-Khayat, B, Boua, P, Favé, M, Francioli, L, Lemaçon, A, Migeotte, I, Patel, S, Varnai, R, Szentpeteri, J, Sipeky, C, Colombo, F, von Hohenstaufen, K, Lio, P, Vallerga, C, Wang, Q, Tanigawa, Y, Im, H, Han, C, Song, H, Lim, J, Lee, Y, Kim, S, Im, S, Atanasovska, B, Ahmad, H, Boer, C, Jansen, P, Franke, L, Kaja, E, Pasko, D, Kennis-Szilagyi, I, Kornilov, S, Prijatelj, V, Prokić, I, Sivanadhan, I, Perumal, S, Esmaeeli, S, Pearson, N, Auton, A, Shelton, J, Shastri, A, Filshtein-Sonmez, T, Coker, D, Symons, A, Esparza-Gordillo, J, Aslibekyan, S, O’Connell, J, Ye, C, Weldon, C, Perera, M, O’Leary, K, Tuck, M, O’Brien, T, Meltzer, D, O’Donnell, P, Nutescu, E, Yang, G, Alarcon, C, Herrmann, S, Mazurek, S, Banagan, J, Hamidi, Z, Barbour, A, Raffat, N, Moreno, D, Friedman, P, Ferwerda, B, van de Beek, D, Brouwer, M, Vlaar, A, Wiersinga, W, Posthuma, D, Tissink, E, Koos Zwinderman, A, Uffelmann, E, van Agtmael, M, Algera, A, van Baarle, F, Bax, D, Beudel, M, Jan Bogaard, H, Bomers, M, Bonta, P, Bos, L, Botta, M, de Brabander, J, de Bree, G, de Bruin, S, Bugiani, M, Bulle, E, Chouchane, O, Cloherty, A, Dongelmans, D, Elbers, P, Fleuren, L, Geerlings, S, Geerts, B, Geijtenbeek, T, Girbes, A, Goorhuis, B, Grobusch, M, Hafkamp, F, Hagens, L, Hamann, J, Harris, V, Hemke, R, Hermans, S, Heunks, L, Hollmann, M, Horn, J, Hovius, J, de Jong, M, Koning, R, van Mourik, N, Nellen, J, Nossent, E, Paulus, F, Peters, E, van der Poll, T, Preckel, B, Prins, J, Raasveld, J, Reijnders, T, Schinkel, M, Schultz, M, Schuurman, A, Sigaloff, K, Smit, M, Stijnis, C, Stilma, W, Teunissen, C, Thoral, P, Tsonas, A, van der Valk, M, Veelo, D, de Vries, H, van Vugt, M, Wouters, D, Minnaar, R, Kromhout, A, van Uffelen, K, Wolterman, R, Roberts, G, Park, D, Ball, C, Coignet, M, Mccurdy, S, Knight, S, Partha, R, Rhead, B, Zhang, M, Berkowitz, N, Gaddis, M, Noto, K, Ruiz, L, Pavlovic, M, Hong, E, Rand, K, Girshick, A, Guturu, H, Baltzell, A, Guntz, J, Beguin, Y, Pigazzini, S, Nkambule, L, Bouysran, Y, Busson, A, Peyrassol, X, Wilkin, F, Pichon, B, Smits, G, Vandernoot, I, Goffard, J, Georges, M, Moutschen, M, Misset, B, Darcis, G, Guiot, J, Jadot, L, Azarzar, S, Dellot, P, Gofflot, S, Claassen, S, Bertrand, A, Parzibut, G, Clarinval, M, Moermans, C, Malaise, O, El Kandoussi, K, Thonon, R, Huynen, P, Mesdagh, A, Melo, S, Jacques, N, Di Valentin, E, Giroule, F, Collignon, A, Radermecker, C, Lebrun, M, Perée, H, Latour, S, Barada, O, Sanchez, J, Josse, C, Boujemla, B, Meunier, M, Mariavelle, E, Anania, S, Gazon, H, Juszczak, D, Fadeur, M, Camby, S, Meuris, C, Thys, M, Jacques, J, Henket, M, Léonard, P, Frippiat, F, Giot, J, Sauvage, A, Von Frenckell, C, Mni, M, Wéry, M, Staderoli, A, Belhaj, Y, Lambermont, B, Morrison, D, Mooser, V, Forgetta, V, Ghosh, B, Laurent, L, Belisle, A, Henry, D, Abdullah, T, Adeleye, O, Mamlouk, N, Kimchi, N, Afrasiabi, Z, Rezk, N, Vulesevic, B, Bouab, M, Guzman, C, Petitjean, L, Tselios, C, Xue, X, Afilalo, J, Afilalo, M, Oliveira, M, Brenner, B, Brassard, N, Durand, M, Schurr, E, Lepage, P, Ragoussis, J, Auld, D, Chassé, M, Kaufmann, D, Lathrop, G, Adra, D, Cox, N, Below, J, Sealock, J, Shuey, M, Polikowsky, H, Petty, L, Shaw, D, Chen, H, Zhu, W, Ludwig, K, Schröder, J, Maj, C, Rolker, S, Nöthen, M, Fazaal, J, Keitel, V, Jensen, B, Feldt, T, Kurth, I, Marx, N, Dreher, M, Pink, I, Cornberg, M, Illig, T, Lehmann, C, Schommers, P, Augustin, M, Rybniker, J, Knopp, L, Eggermann, T, Volland, S, Altmüller, J, Berger, M, Brenner, T, Hinney, A, Witzke, O, Bals, R, Herr, C, Ludwig, N, Walter, J, Fuchsberger, C, Pattaro, C, De Grandi, A, Pramstaller, P, Emmert, D, Melotti, R, Foco, L, Mascalzoni, D, Gögele, M, Domingues, F, Hicks, A, Gignoux, C, Wicks, S, Crooks, K, Barnes, K, Daya, M, Shortt, J, Rafaels, N, Chavan, S, Goldstein, D, Kiryluk, K, Sengupta, S, Chung, W, Reilly, M, Khan, A, Wang, C, Povysil, G, Bhardwaj, N, Gharavi, A, Ionita-Laza, I, Shang, N, O’Byrne, S, Nandakumar, R, Menon, A, So, Y, Hod, E, Pendrick, D, Park, S, Kang, C, Lee, H, Song, K, Jae Yoon, K, Paik, N, Seok, W, Yoon, H, Joo, E, Chang, Y, Ryu, S, Park, W, Su Park, J, Un Park, K, Ham, S, Jung, J, Kim, E, Ellinghaus, D, Degenhardt, F, Cáceres, M, Juzenas, S, Lenz, T, Albillos, A, Julià, A, Heidecker, B, Garcia, F, Kurth, F, Tran, F, Hanses, F, Zoller, H, Holter, J, Fernández, J, Sander, L, Rosenstiel, P, Koehler, P, de Cid, R, Asselta, R, Schreiber, S, Hehr, U, Prati, D, Baselli, G, Valenti, L, Bujanda, L, Banales, J, Duga, S, D’Amato, M, Romero-Gómez, M, Buti, M, Invernizzi, P, Franke, A, Hov, J, Karlsen, T, Folseraas, T, Maya-Miles, D, Teles, A, Azuure, C, Wacker, E, Uellendahl-Werth, F, Elabd, H, Arora, J, Lerga-Jaso, J, Wienbrandt, L, Rühlemann, M, Wendorff, M, Vadla, M, Lenning, O, Özer, O, Myhre, R, Raychaudhuri, S, Tanck, A, Gassner, C, Hemmrich-Stanisak, G, Kässens, J, Figuera Basso, M, Schulzky, M, Wittig, M, Braun, N, Wesse, T, Albrecht, W, Yi, X, Ortiz, A, Chercoles, A, Ruiz, A, Mantovani, A, Holten, A, Mayer, A, Cherubini, A, Protti, A, Aghemo, A, Gerussi, A, Ramirez, A, Braun, A, Barreira, A, Lleo, A, Kildal, A, Glück, A, Nolla, A, Latiano, A, Dyrhol-Riise, A, Muscatello, A, Voza, A, Rando-Segura, A, Solier, A, Karina, B, Cortes, B, Mateos, B, Nafria-Jimenez, B, Schaefer, B, Bellinghausen, C, Ferrando, C, Quereda, C, Skurk, C, Thibeault, C, Spinner, C, Lange, C, Hu, C, Cappadona, C, Bianco, C, Sancho, C, Lihaug Hoff, D, Galimberti, D, Jiménez, D, Pestaña, D, Toapanta, D, Azzolini, E, Scarpini, E, Helbig, E, Urrechaga, E, Paraboschi, E, Pontali, E, Reverter, E, Navas, E, Arana, E, Sánchez, F, Ceriotti, F, Malvestiti, F, Mesonero, F, Pezzoli, G, Lamorte, G, Neb, H, My, I, Hernández, I, de Rojas, I, Galván-Femenia, I, Heyckendorf, J, Badia, J, Schneider, J, Goikoetxea, J, Kraft, J, Müller, K, Gaede, K, Garcia-Etxebarria, K, Tonby, K, Heggelund, L, Izquierdo-Sanchez, L, Sumoy, L, Lippert, L, Terranova, L, Garbarino, L, Téllez, L, Roade, L, Ostadreza, M, Intxausti, M, Kogevinas, M, Gutiérrez-Stampa, M, Vehreschild, M, Marquié, M, Castoldi, M, Cecconi, M, Boada, M, Seilmaier, M, Mazzocco, M, Rodríguez-Gandía, M, Ayo, N, Blay, N, Martínez, N, Cornely, O, Palmieri, O, Tentorio, P, Rodrigues, P, España, P, Hoffmann, P, Bacher, P, Suwalski, P, de Pablo, R, Nieto, R, Badalamenti, S, Ciesek, S, Bombace, S, Wilfling, S, Brunak, S, Heilmann-Heimbach, S, Ripke, S, Bahmer, T, Landmesser, U, Protzer, U, Rimoldi, V, Skogen, V, Andrade, V, Moreno, V, Poller, W, Farre, X, Wang, X, Khodamoradi, Y, Karadeniz, Z, de Salazar, A, Palom, A, Garcia-Fernandez, A, Blanco-Grau, A, Zanella, A, Bandera, A, Nebel, A, Biondi, A, Caballero-Garralda, A, Gori, A, Lind, A, Fracanzani, A, Peschuck, A, Pesenti, A, de la Horra, C, Milani, C, Paccapelo, C, Angelini, C, Cea, C, Muñiz-Diaz, E, Sandoval, E, Calderón, E, Solligård, E, Aziz, F, Martinelli-Boneschi, F, Peyvandi, F, Blasi, F, Medrano, F, Rodriguez-Frias, F, Müller, F, Grasselli, G, Costantino, G, Cardamone, G, Foti, G, Matullo, G, Kurihara, H, Afset, J, Damås, J, Ampuero, J, Martín, J, Erdmann, J, Bergan, J, Goerg, S, Ferrusquía-Acosta, J, Quero, J, Delgado, J, Guerrero, J, Risnes, K, Bettini, L, Moreira, L, Gustad, L, Santoro, L, Scudeller, L, Riveiro-Barciela, M, Schaefer, M, Carrabba, M, Valsecchi, M, Hernandez-Tejero, M, Acosta-Herrera, M, D’Angiò, M, Baldini, M, Cazzaniga, M, Ciccarelli, M, Bocciolone, M, Miozzo, M, Chueca, N, Montano, N, Faverio, P, Preatoni, P, Bonfanti, P, Omodei, P, Castro, P, Ferrer, R, Gualtierotti, R, Gallego-Durán, R, Morilla, R, Haider, S, Marsal, S, Aneli, S, Pelusi, S, Bosari, S, Aliberti, S, Dudman, S, Zheng, T, Pumarola, T, Cejudo, T, Monzani, V, Friaza, V, Peter, W, Dopazo, X, May, S, Grimsrud, M, Gudbjartsson, D, Stefansson, K, Sulem, P, Sveinbjornsson, G, Melsted, P, Norddahl, G, Swerford Moore, K, Thorsteinsdottir, U, Holm, H, Alarcón-Riquelme, M, Bernardo, D, Martínez-Bueno, M, Rello, S, Magi, R, Milani, L, Metspalu, A, Laisk, T, Läll, K, Lepamets, M, Esko, T, Reimann, E, Naaber, P, Laane, E, Pesukova, J, Peterson, P, Kisand, K, Tabri, J, Allos, R, Hensen, K, Starkopf, J, Ringmets, I, Tamm, A, Kallaste, A, Alavere, H, Metsalu, K, Puusepp, M, Kristiansson, K, Koskelainen, S, Perola, M, Donner, K, Kivinen, K, Palotie, A, Rivolta, C, Bochud, P, Bibert, S, Boillat, N, Nussle, S, Albrich, W, Quinodoz, M, Kamdar, D, Suh, N, Neofytos, D, Erard, V, Voide, C, Friolet, R, Vollenweider, P, Pagani, J, Oddo, M, zu Bentrup, F, Conen, A, Clerc, O, Marchetti, O, Guillet, A, Guyat-Jacques, C, Foucras, S, Rime, M, Chassot, J, Jaquet, M, Viollet, R, Lannepoudenx, Y, Portopena, L, Desgranges, F, Filippidis, P, Guéry, B, Haefliger, D, Kampouri, E, Manuel, O, Munting, A, Papadimitriou-Olivgeris, M, Regina, J, Rochat-Stettler, L, Suttels, V, Tadini, E, Tschopp, J, Van Singer, M, Viala, B, Boillat-Blanco, N, Brahier, T, Hügli, O, Meuwly, J, Pantet, O, Bochud, M, D’Acremont, V, Younes, S, Cerny, A, O’Mahony, L, von Mering, C, Frischknecht, M, Kleger, G, Filipovic, M, Kahlert, C, Wozniak, H, Negro, T, Pugin, J, Bouras, K, Knapp, C, Egger, T, Perret, A, Montillier, P, di Bartolomeo, C, Barda, B, Carreras, A, Galván-Femenía, I, Farré, X, Cortés, B, Mercader, J, Guindo-Martinez, M, Torrents, D, Garcia-Aymerich, J, Castaño-Vinyals, G, Dobaño, C, Gori, M, Mondelli, M, Castelli, F, Vaghi, M, Rusconi, S, Montagnani, F, Bargagli, E, Franchi, F, Mazzei, M, Cantarini, L, Tacconi, D, Feri, M, Scala, R, Spargi, G, Nencioni, C, Bandini, M, Caldarelli, G, Spagnesi, M, Canaccini, A, Ognibene, A, D’Arminio Monforte, A, Girardis, M, Antinori, A, Francisci, D, Schiaroli, E, Scotton, P, Panese, S, Scaggiante, R, Monica, M, Capasso, M, Fiorentino, G, Castori, M, Aucella, F, Di Biagio, A, Masucci, L, Valente, S, Mandalà, M, Zucchi, P, Giannattasio, F, Coviello, D, Mussini, C, Bosio, G, Tavecchia, L, Crotti, L, Rizzi, M, La Rovere, M, Sarzi-Braga, S, Bussotti, M, Ravaglia, S, Artuso, R, Perrella, A, Romani, D, Bergomi, P, Catena, E, Vincenti, A, Ferri, C, Grassi, D, Pessina, G, Tumbarello, M, Di Pietro, M, Sabrina, R, Luchi, S, Barbieri, C, Acquilini, D, Andreucci, E, Paciosi, F, Segala, F, Tiseo, G, Falcone, M, Lista, M, Poscente, M, De Vivo, O, Petrocelli, P, Guarnaccia, A, Baroni, S, Perticaroli, V, Furini, S, Dei, S, Benetti, E, Picchiotti, N, Sanarico, M, Ceri, S, Pinoli, P, Raimondi, F, Biscarini, F, Stella, A, Bergomi, M, Zguro, K, Capitani, K, Tanfoni, M, Fallerini, C, Daga, S, Baldassarri, M, Fava, F, Frullanti, E, Valentino, F, Doddato, G, Giliberti, A, Tita, R, Amitrano, S, Bruttini, M, Croci, S, Meloni, I, Mencarelli, M, Lo Rizzo, C, Pinto, A, Beligni, G, Tommasi, A, Di Sarno, L, Palmieri, M, Carriero, M, Alaverdian, D, Iuso, N, Inchingolo, G, Busani, S, Bruno, R, Vecchia, M, Belli, M, Mantovani, S, Ludovisi, S, Quiros-Roldan, E, Antoni, M, Zanella, I, Siano, M, Emiliozzi, A, Fabbiani, M, Rossetti, B, Zanelli, G, Bergantini, L, D’Alessandro, M, Cameli, P, Bennet, D, Anedda, F, Marcantonio, S, Scolletta, S, Guerrini, S, Conticini, E, Frediani, B, Spertilli, C, Donati, A, Guidelli, L, Corridi, M, Croci, L, Piacentini, P, Desanctis, E, Cappelli, S, Verzuri, A, Anemoli, V, Pancrazi, A, Lorubbio, M, Merlini, E, Miraglia, F, Venturelli, S, Cossarizza, A, Vergori, A, Gabrieli, A, Riva, A, Andretta, F, Gatti, F, Parisi, S, Baratti, S, Piscopo, C, Russo, R, Andolfo, I, Iolascon, A, Carella, M, Merla, G, Squeo, G, Raggi, P, Marciano, C, Perna, R, Bassetti, M, Sanguinetti, M, Giorli, A, Salerni, L, Parravicini, P, Menatti, E, Trotta, T, Coiro, G, Lena, F, Martinelli, E, Mancarella, S, Gabbi, C, Maggiolo, F, Ripamonti, D, Bachetti, T, Suardi, C, Parati, G, Bottà, G, Di Domenico, P, Rancan, I, Bianchi, F, Colombo, R, Hunt, K, Trembath, R, Huang, Q, Martin, H, Mason, D, Trivedi, B, Wright, J, Finer, S, Griffiths, C, Akhtar, S, Anwar, M, Arciero, E, Ashraf, S, Breen, G, Chung, R, Curtis, C, Chowdhury, M, Colligan, G, Deloukas, P, Durham, C, Hurles, M, Hussain, S, Islam, K, Lavery, C, Lerner, R, Macarthur, D, Maclaughlin, B, Miah, S, Newman, B, Safa, N, Tahmasebi, F, Smith, A, Boughton, A, Li, K, Lefaive, J, Annis, A, Jannes, C, Krieger, J, Pereira, A, Velho, M, Marques, E, Lima, I, Tada, M, Valino, K, Mccarthy, M, Rosenberger, C, Lee, J, Chang, D, Hammer, C, Hunkapiller, J, Mahajan, A, Pendergrass, S, Sucheston-Campbell, L, Yaspan, B, Shin, E, Jang, H, Kym, S, Kim, Y, Jeong, H, Kwon, K, Kim, J, Jang, Y, Choe, K, Kang, Y, Jee, S, Jung, K, Parikh, V, Ashley, E, Wheeler, M, Rivas, M, Bustamante, C, Pinksy, B, Febbo, P, Farh, K, Schroth, G, Desouza, F, Dalton, K, Christle, J, Deboever, C, Szalma, S, Rubinacci, S, Delaneau, O, Gorzynski, J, de Jong, H, Sutton, S, Youlton, N, Joshi, R, Jimenez-Morales, D, Hughes, C, Amar, D, Ioannidis, A, Hershman, S, Kirillova, A, Seo, K, Huang, Y, Shoura, M, Hammond, N, Watson, N, Raja, A, Huang, C, Sahoo, M, Wang, H, Zhen, J, Rakitko, A, Ilinsky, V, Yermakovich, D, Popov, I, Chernitsov, A, Kovalenko, E, Krasnenko, A, Plotnikov, N, Stetsenko, I, Kim, A, Cirulli, E, Schiabor Barrett, K, Bolze, A, White, S, Washington, N, Lu, J, Riffle, S, Tanudjaja, F, Ramirez, J, Leonetti, N, Neveux, I, Dabe, S, Grzymski, J, Esteban Miñano, J, Aguirre, L, López-Collazo, E, de la Mata Pazos, M, Cerrato, L, Lozano-Rodríguez, R, Avendaño-Ortiz, J, Arcos, V, Montalbán-Hernández, K, Quiroga, J, Pascual-Iglesias, A, Maroun-Eid, C, Martín-Quirós, A, Namkoong, H, Imoto, S, Katayama, K, Fukunaga, K, Kitagawa, Y, Sato, T, Hasegawa, N, Kumanogoh, A, Kimura, A, Ai, M, Tokunaga, K, Kanai, T, Miyano, S, Ogawa, S, Edahiro, R, Sonehara, K, Shirai, Y, Ishii, M, Kabata, H, Masaki, K, Kamata, H, Ikemura, S, Chubachi, S, Okamori, S, Terai, H, Tanaka, H, Morita, A, Asakura, T, Sasaki, J, Morisaki, H, Uwamino, Y, Nanki, K, Mikami, Y, Tomono, K, Kato, K, Matsuda, F, Takahashi, M, Hizawa, N, Takeda, Y, Hirata, H, Shiroyama, T, Miyawaki, S, Suzuki, K, Maeda, Y, Nii, T, Noda, Y, Niitsu, T, Adachi, Y, Enomoto, T, Amiya, S, Hara, R, Takahashi, K, Anzai, T, Hasegawa, T, Ito, S, Koike, R, Endo, A, Uchimura, Y, Miyazaki, Y, Honda, T, Tateishi, T, Tohda, S, Ichimura, N, Sonobe, K, Sassa, C, Nakajima, J, Nannya, Y, Omae, Y, Harada, N, Hiki, M, Takagi, H, Nakamura, A, Tagaya, E, Kawana, M, Arimura, K, Ishiguro, T, Takayanagi, N, Isono, T, Takaku, Y, Takano, K, Anan, R, Nakajima, Y, Nakano, Y, Nishio, K, Ueda, S, Hayashi, R, Tateno, H, Hase, I, Yoshida, S, Suzuki, S, Mitamura, K, Saito, F, Ueda, T, Azuma, M, Nagasaki, T, Yasui, Y, Hasegawa, Y, Mutoh, Y, Yoshiyama, T, Shoko, T, Kojima, M, Adachi, T, Ishikawa, M, Watanabe, K, Manabe, T, Ito, F, Fukui, T, Funatsu, Y, Koh, H, Hirai, Y, Kawashima, H, Narita, A, Niwa, K, Sekikawa, Y, Yoshiya, K, Yoshihara, T, Suzuki, Y, Nakayama, S, Masuzawa, K, Nishi, K, Nishitsuji, M, Tani, M, Inoue, T, Hirano, T, Kobayashi, K, Miyazawa, N, Kimura, Y, Sado, R, Ogura, T, Kitamura, H, Murohashi, K, Nakachi, I, Baba, R, Arai, D, Fuke, S, Saito, H, Kuwahara, N, Fujiwara, A, Okada, T, Baba, T, Noda, J, Mashimo, S, Yagi, K, Shiomi, T, Hashiguchi, M, Odani, T, Mochimaru, T, Oyamada, Y, Mori, N, Izumi, N, Nagata, K, Taki, R, Murakami, K, Yamada, M, Sugiura, H, Hayashi, K, Shimizu, T, Gon, Y, Fujitani, S, Tsuchida, T, Yoshida, T, Kagaya, T, Kita, T, Sakagami, S, Kimizuka, Y, Kawana, A, Nakamura, Y, Ishikura, H, Takata, T, Kikuchi, T, Taniyama, D, Nakamura, M, Kodama, N, Kaneyama, Y, Maeda, S, Nagasaki, Y, Okamoto, M, Ishihara, S, Ito, A, Chihara, Y, Takeuchi, M, Onoi, K, Hashimoto, N, Wakahara, K, Ando, A, Masuda, M, Wakabayashi, A, Watanabe, H, Sageshima, H, Nakada, T, Abe, R, Shimada, T, Kawamura, K, Ichikado, K, Nishiyama, K, Yamasaki, M, Hashimoto, S, Kusaka, Y, Ohba, T, Isogai, S, Takada, M, Kanda, H, Komase, Y, Sano, F, Asano, K, Oguma, T, Harada, M, Takahashi, T, Shibusawa, T, Abe, S, Kono, Y, Togashi, Y, Izumo, T, Inomata, M, Awano, N, Ogata, T, Kanehiro, A, Ozaki, S, Fuchimoto, Y, Ogura, S, Yoshida, K, Beppu, S, Fukuyama, S, Eriguchi, Y, Yonekawa, A, Inoue, Y, Yamagata, K, Chiba, S, Narumoto, O, Nagai, H, Ooshima, N, Motegi, M, Sagara, H, Tanaka, A, Ohta, S, Shibata, Y, Tanino, Y, Sato, Y, Yamada, Y, Hashino, T, Shinoki, M, Iwagoe, H, Imamura, T, Umeda, A, Shimada, H, Endo, M, Hayashi, S, Nakano, S, Yatomi, M, Maeno, T, Ishii, T, Utsugi, M, Ono, A, Kanaoka, K, Ihara, S, Komuta, K, Boezen, M, Claringbould, A, Lopera, E, Warmerdam, R, Vonk, J, van Blokland, I, Lanting, P, Ori, A, Obeidat, M, Hernández Cordero, A, Sin, D, Bossé, Y, Joubert, P, Hao, K, Nickle, D, Timens, W, van den Berge, M, Feng, Y, Weiss, S, Karlson, E, Smoller, J, Murphy, S, Meigs, J, Woolley, A, Green, R, Perez, E, Zöllner, S, Wang, J, Beck, A, Ascolillo, S, Sebra, R, Collins, B, Levy, T, Sealfon, S, Jordan, D, Thompson, R, Gettler, K, Chaudhary, K, Belbin, G, Preuss, M, Hoggart, C, Choi, S, Underwood, S, Salib, I, Britvan, B, Keller, K, Tang, L, Peruggia, M, Hiester, L, Niblo, K, Aksentijevich, A, Labkowsky, A, Karp, A, Zlatopolsky, M, Zyndorf, M, Charney, A, Beckmann, N, Schadt, E, Abul-Husn, N, Cho, J, Itan, Y, Kenny, E, Loos, R, Nadkarni, G, Do, R, O’Reilly, P, Huckins, L, Ferreira, M, Abecasis, G, Leader, J, Cantor, M, Justice, A, Carey, D, Chittoor, G, Josyula, N, Kosmicki, J, Horowitz, J, Baras, A, Gass, M, Yadav, A, Mirshahi, T, Jan Hottenga, J, Bartels, M, de Geus, E, Nivard, M, Verma, A, Ritchie, M, Rader, D, Li, B, Verma, S, Lucas, A, Bradford, Y, Zara, F, Salpietro, V, Scala, M, Iacomino, M, Scudieri, P, Bocciardi, R, Minetti, C, Vari, M, Rahier, J, Giorgio, E, Carli, D, Louis, E, Bulik, C, Landén, M, Brusco, A, Ferrero, G, Madia, F, Fundín, B, Ismail, S, Saad, C, Al-Sarraj, Y, Badji, R, Al-Muftah, W, Al Thani, A, Afifi, N, Klovins, J, Rovite, V, Rescenko, R, Peculis, R, Ustinova, M, Zeberg, H, Frithiof, R, Hultström, M, Lipcsey, M, Johnson, R, Geschwind, D, Freimer, N, Butte, M, Ding, Y, Chiu, A, Chang, T, Boutros, P, Moutsianas, L, Caulfield, M, Scott, R, Walker, S, Stuckey, A, Odhams, C, Rhodes, D, Fowler, T, Rendon, A, Chan, G, Arumugam, P, Karczewski, K, Wilson, D, Spencer, C, Crook, D, Wyllie, D, O’Connell, A, Atkinson, E, Tsuo, K, Baya, N, Turley, P, Gupta, R, Walters, R, Palmer, D, Sarma, G, Cheng, N, Lu, W, Churchhouse, C, Goldstein, J, King, D, Seed, C, Bryant, S, Satterstrom, F, Band, G, Earle, S, Lin, S, Arning, N, Armstrong, J, Rudkin, J, Callier, S, Cusick, C, Soranzo, N, Zhao, J, Danesh, J, Di Angelantonio, E, Butterworth, A, Sun, Y, Huffman, J, Cho, K, O’Donnell, C, Tsao, P, Gaziano, J, Peloso, G, Ho, Y, Mian, M, Scaggiante, F, Chang, X, Glessner, J, Hakonarson, H, Mcguigan, P, Prockter Moore, L, Vizcaychipi, M, Hall, K, Campbell, A, Nichol, A, Ward, G, Page, V, Semple, M, Adeniji, K, Agranoff, D, Agwuh, K, Ail, D, Aldera, E, Alegria, A, Angus, B, Ashish, A, Atkinson, D, Bari, S, Barlow, G, Barnass, S, Barrett, N, Bassford, C, Basude, S, Baxter, D, Beadsworth, M, Bernatoniene, J, Berridge, J, Best, N, Bothma, P, Chadwick, D, Brittain-Long, R, Bulteel, N, Burden, T, Burtenshaw, A, Caruth, V, Chambler, D, Chee, N, Child, J, Chukkambotla, S, Clark, T, Collini, P, Cosgrove, C, Cupitt, J, Cutino-Moguel, M, Dark, P, Dawson, C, Dervisevic, S, Donnison, P, Douthwaite, S, Drummond, A, Durand, I, Dushianthan, A, Dyer, T, Evans, C, Eziefula, C, Fegan, C, Finn, A, Fullerton, D, Garg, S, Garg, A, Gkrania-Klotsas, E, Godden, J, Goldsmith, A, Graham, C, Hardy, E, Hartshorn, S, Harvey, D, Havalda, P, Hawcutt, D, Hobrok, M, Hodgson, L, Hormis, A, Jacobs, M, Jain, S, Jennings, P, Kaliappan, A, Kasipandian, V, Kegg, S, Kelsey, M, Kendall, J, Kerrison, C, Kerslake, I, Koch, O, Koduri, G, Koshy, G, Laha, S, Laird, S, Larkin, S, Leiner, T, Lillie, P, Limb, J, Linnett, V, Little, J, Lyttle, M, Macmahon, M, Macnaughton, E, Mankregod, R, Masson, H, Matovu, E, Mccullough, K, Mcewen, R, Meda, M, Mills, G, Minton, J, Ward, K, Mirfenderesky, M, Mohandas, K, Mok, Q, Moon, J, Moore, E, Morgan, P, Morris, C, Mortimore, K, Moses, S, Mpenge, M, Mulla, R, Murphy, M, Nagel, M, Nagarajan, T, Nelson, M, O’Shea, M, Otahal, I, Ostermann, M, Pais, M, Panchatsharam, S, Papakonstantinou, D, Paraiso, H, Patel, B, Pattison, N, Pepperell, J, Peters, M, Phull, M, Pintus, S, Pooni, J, Post, F, Price, D, Prout, R, Rae, N, Reschreiter, H, Reynolds, T, Richardson, N, Roberts, M, Roberts, D, Rose, A, Rousseau, G, Ryan, B, Saluja, T, Shah, A, Shanmuga, P, Sharma, A, Shawcross, A, Sizer, J, Shankar-Hari, M, Smith, R, Snelson, C, Spittle, N, Staines, N, Stambach, T, Stewart, R, Subudhi, P, Szakmany, T, Tatham, K, Thomas, J, Thompson, C, Tridente, A, Tupper-Carey, D, Twagira, M, Ustianowski, A, Vallotton, N, Vincent-Smith, L, Visuvanathan, S, Vuylsteke, A, Waddy, S, Wake, R, Walden, A, Welters, I, Whitehouse, T, Whittaker, P, Whittington, A, Papineni, P, Wijesinghe, M, Williams, M, Wilson, L, Cole, S, Winchester, S, Wiselka, M, Wolverson, A, Wooton, D, Workman, A, Yates, B, Young, P, Beale, R, Bretherick, A, Clohisey, S, Fourman, M, Furniss, J, Gountouna, E, Grimes, G, Haley, C, Harrison, D, Hayward, C, Keating, S, Klaric, L, Klenerman, P, Law, A, Meynert, A, Millar, J, Pairo-Castineira, E, Parkinson, N, Ponting, C, Porteous, D, Rawlik, K, Richmond, A, Rowan, K, Russell, C, Shen, X, Shih, B, Tenesa, A, Vitart, V, Wang, B, Wilson, J, Wu, Y, Yang, J, Yang, Z, Zechner, M, Zhai, R, Zheng, C, Norman, L, Pius, R, Drake, T, Fairfield, C, Mclean, K, Murphy, D, Shaw, C, Dalton, J, Girvan, M, Saviciute, E, Roberts, S, Harrison, J, Marsh, L, Connor, M, Halpin, S, Jackson, C, Gamble, C, Leeming, G, Wham, M, Hendry, R, Scott-Brown, J, Begg, C, Hinds, C, Wai Ho, A, Horby, P, Knight, J, Ling, L, Maslove, D, Mcauley, D, Montgomery, H, Openshaw, P, Summers, C, Walsh, T, Armstrong, L, Bates, H, Dooks, E, Farquhar, F, Hairsine, B, Mcparland, C, Packham, S, Alldis, Z, Astin-Chamberlain, R, Bibi, F, Biddle, J, Blow, S, Bolton, M, Borra, C, Bowles, R, Burton, M, Choudhury, Y, Collier, D, Cox, A, Easthope, A, Ebano, P, Fotiadis, S, Gurasashvili, J, Halls, R, Hartridge, P, Kallon, D, Kassam, J, Lancoma-Malcolm, I, Matharu, M, May, P, Mitchelmore, O, Newman, T, Patel, M, Pheby, J, Pinzuti, I, Prime, Z, Prysyazhna, O, Shiel, J, Taylor, M, Tierney, C, Wood, S, Zak, A, Zongo, O, Forsey, M, Nicholson, A, Riches, J, Vertue, M, Wasson, C, Finn, S, Green, J, Collins, E, King, B, Grauslyte, L, Hussain, M, Pogreban, T, Rosaroso, L, Salciute, E, Franke, G, Wong, J, George, A, Akeroyd, L, Bano, S, Bromley, M, Gurr, L, Lawton, T, Morgan, J, Sellick, K, Warren, D, Wilkinson, B, Mcgowan, J, Ledgard, C, Stacey, A, Pye, K, Bellwood, R, Bentley, M, Loosley, R, Mcguinness, H, Tench, H, Wolf-Roberts, R, Gibson, S, Lyle, A, Mcneela, F, Radhakrishnan, J, Hughes, A, Ali, A, Brady, M, Dale, S, Dance, A, Gledhill, L, Greig, J, Hanson, K, Holdroyd, K, Home, M, Kelly, D, Kitson, R, Matapure, L, Melia, D, Mellor, S, Nortcliffe, T, Pinnell, J, Robinson, M, Shaw, L, Shaw, R, Thomis, L, Wilson, A, Wood, T, Bayo, L, Merwaha, E, Ishaq, T, Hanley, S, Antcliffe, D, Banach, D, Brett, S, Coghlan, P, Fernandez, Z, Gordon, A, Rojo, R, Arias, S, Templeton, M, Jha, R, Krishnamurthy, V, Lim, L, Bi, R, Scholefield, B, Ashton, L, Williams, A, Cheyne, C, Saunderson, A, Allan, A, Anderson, F, Kaye, C, Liew, J, Medhora, J, Scott, T, Trumper, E, Botello, A, Polgarova, P, Stroud, K, Meaney, E, Jones, M, Ng, A, Agrawal, S, Pathan, N, White, D, Daubney, E, Elston, K, Parker, R, Reddy, A, Turner-Bone, I, Wilding, L, Harding, P, Jacob, R, Jones, C, Denmade, C, Croft, M, White, I, Griffin, D, Muchenje, N, Mupudzi, M, Partridge, R, Conyngham, J, Thomas, R, Wright, M, Corral, M, Bastion, V, Clarke, D, David, B, Kent, H, Lorusso, R, Lubimbi, G, Murdoch, S, Penacerrada, M, Thomas, A, Valentine, J, Vochin, A, Wulandari, R, Djeugam, B, Dawson, J, Garrioch, S, Tolson, M, Aldridge, J, de Almeida Martins, L, Carungcong, J, Beavis, S, Dale, K, Gascoyne, R, Hawes, J, Pritchard, K, Stevenson, L, Whileman, A, Cowley, A, Highgate, J, Crawley, R, Crew, A, Cunningham, M, Daniels, A, Harrison, L, Hope, S, Inweregbu, K, Jones, S, Lancaster, N, Matthews, J, Wray, G, Benham, L, Bradshaw, Z, Brown, J, Caswell, M, Melling, S, Preston, S, Slawson, N, Stoddard, E, Warden, S, Combes, E, Joefield, T, Monnery, S, Beech, V, Trotman, S, Hopkins, B, Scriven, J, Thrasyvoulou, L, Willis, H, Anderson, S, Birch, J, Hammerton, K, O’Leary, R, Abernathy, C, Foster, L, Gratrix, A, Martinson, V, Parkinson, P, Stones, E, Carbral-Ortega, L, Kapoor, R, Loader, D, Castle, K, Brandwood, C, Smith, L, Clark, R, Birchall, K, Kolakaluri, L, Baines, D, Sukumaran, A, Mapfunde, I, Meredith, M, Morris, L, Ryan, L, Clark, A, Sampson, J, Peters, C, Dent, M, Langley, M, Wei, S, Andrew, A, Chablani, M, Kirkby, A, Netherton, K, Bates, M, Dasgin, J, Gill, J, Nilsson, A, Apetri, E, Basikolo, C, Blackledge, B, Catlow, L, Charles, B, Doonan, R, Harris, J, Harvey, A, Horner, D, Knowles, K, Lomas, D, Lyons, C, Marsden, T, Mclaughlan, D, Mcmorrow, L, Pendlebury, J, Perez, J, Poulaka, M, Proudfoot, N, Slaughter, M, Slevin, K, Thomas, V, Walker, D, Michael, A, Collis, M, Clark, M, Coulding, M, Jude, E, Mccormick, J, Mercer, O, Potla, D, Rehman, H, Savill, H, Turner, V, Davey, M, Golden, D, Seaman, R, Hunt, J, Dearden, J, Dobson, E, Mulcahy, M, Munt, S, O’Connor, G, Philbin, J, Rishton, C, Tully, R, Winnard, S, Cagova, L, Fofano, A, Garner, L, Holcombe, H, Mepham, S, Mitchell, A, Mwaura, L, Praman, K, Zamikula, J, Bercades, G, Brealey, D, Hass, I, Maccallum, N, Martir, G, Raith, E, Reyes, A, Smyth, D, Taylor, A, Hughes, R, Thomas, H, Rees, A, Duskova, M, Phipps, J, Brooks, S, Edwards, M, Alexander, P, Allen, S, Bradley-Potts, J, Brantwood, C, Egan, J, Felton, T, Padden, G, Ward, L, Moss, S, Glasgow, S, Beesley, K, Board, S, Kubisz-Pudelko, A, Lewis, A, Perry, J, Pippard, L, Wood, D, Buckley, C, Brown, A, Gregory, J, O’Connell, S, Smith, T, Belagodu, Z, Fuller, B, Gherman, A, Olufuwa, O, Paramsothy, R, Stuart, C, Oakley, N, Kamundi, C, Tyl, D, Collins, K, Silva, P, Taylor, J, King, L, Coates, C, Crowley, M, Wakefield, P, Beadle, J, Johnson, L, Sargeant, J, Anderson, M, Jardine, C, Williams, D, Parris, V, Quaid, S, Watson, E, Melville, J, Naisbitt, J, Joseph, R, Lazo, M, Walton, O, Neal, A, Hill, M, Kannan, T, Wild, L, Allan, E, Darlington, K, Davies, F, Easton, J, Kumar, S, Lean, R, Menzies, D, Pugh, R, Qiu, X, Davies, L, Williams, H, Scanlon, J, Davies, G, Mackay, C, Lewis, J, Rees, S, Coetzee, S, Gales, A, Raj, M, Sell, C, Langton, H, Watters, M, Novis, C, Arbane, G, Bociek, A, Campos, S, Grau, N, Jones, T, Lim, R, Marotti, M, Whitton, C, Barron, A, Collins, C, Kaul, S, Passmore, H, Prendergast, C, Reed, A, Rogers, P, Shokkar, R, Woodruff, M, Middleton, H, Polgar, O, Nolan, C, Thwaites, V, Mahay, K, Sri-Chandana, C, Scherewode, J, Stephenson, L, Marsh, S, Bancroft, H, Bellamy, M, Carmody, M, Daglish, J, Moore, F, Rhodes, J, Sangombe, M, Kadiri, S, Ayers, A, Harrison, W, North, J, Cavazza, A, Cockrell, M, Corcoran, E, Depante, M, Finney, C, Jerome, E, Mcphail, M, Nayak, M, Noble, H, O’Reilly, K, Pappa, E, Saha, R, Saha, S, Smith, J, Knighton, A, Gill, M, Paul, P, Ratnam, V, Shelton, S, Wynter, I, Baptista, D, Crowe, R, Fernandes, R, Herdman-Grant, R, Joseph, A, Loveridge, A, Mckenley, I, Morino, E, Naranjo, A, Simms, R, Sollesta, K, Swain, A, Venkatesh, H, Khera, J, Fox, J, Barber, R, Hewitt, C, Hilldrith, A, Jackson-Lawrence, K, Shepardson, S, Wills, M, Butler, S, Tavares, S, Cunningham, A, Hindale, J, Arif, S, George, L, Twiss, S, Wright, D, Holland, M, Keenan, N, Lyons, M, Wassall, H, Marsh, C, Mahenthran, M, Carter, E, Kong, T, Adanini, O, Bhatia, N, Msiska, M, Mew, L, Mwaura, E, Williams, F, Wren, L, Sutherland, S, Battle, C, Brinkworth, E, Harford, R, Murphy, C, Newey, L, Rees, T, Arnold, S, Hardy, J, Houlden, H, Moncur, E, Tariq, A, Tucci, A, Convery, K, Fottrell-Gould, D, Hudig, L, Keshet-Price, J, Randell, G, Stammers, K, Abdelrazik, M, Bakthavatsalam, D, Elhassan, M, Ganesan, A, Haldeos, A, Moreno-Cuesta, J, Purohit, D, Vincent, R, Xavier, K, Rohit, K, Alasdair, F, Saleem, M, David, C, Jenkins, S, Lamond, Z, Wall, A, Reynolds, J, Campbell, H, Thompsom, M, Dodds, S, Duffy, S, Butcher, D, O’Sullivan, S, Butterworth-Cowin, N, Deacon, B, Hibbert, M, Pothecary, C, Tetla, D, Woodford, C, Durga, L, Kennard-Holden, G, de Gordoa, L, Peasgood, E, Phillips, C, Skinner, D, Gaylard, J, Mullan, D, Newman, J, Davies, E, Roche, L, Sathe, S, Brimfield, L, Daly, Z, Pogson, D, Rose, S, Collins, A, Khaliq, W, Gude, E, Allen, L, Beranova, E, Crisp, N, Deery, J, Hazelton, T, Knight, A, Price, C, Tilbey, S, Turki, S, Turney, S, Giles, J, Booth, S, Bell, G, English, K, Katary, A, Wilcox, L, Campbell, R, Clarke, N, Whiteside, J, Mascarenhas, M, Donaldson, A, Matheson, J, Barrett, F, O’Hara, M, O’Keefe, L, Bradley, C, Walker, R, Maynard, V, Patel, T, Smith, M, Kazi, A, Hartley, J, Dykes, J, Hijazi, M, Keith, S, Khan, M, Ryan-Smith, J, Springle, P, Truman, N, Saad, S, Coleman, D, Fine, C, Matt, R, Gay, B, Dalziel, J, Ali, S, Goodchild, D, Harling, R, Bhatterjee, R, Goddard, W, Davison, C, Duberly, S, Hargreaves, J, Bolton, R, Verlander, M, Blackman, H, Creagh-Brown, B, Donlon, S, Michalak-Glinska, N, Mtuwa, S, Pristopan, V, Salberg, A, Smith, E, Stone, S, Piercy, C, Verula, J, Burda, D, Montaser, R, Harden, L, Mayangao, I, Marriott, C, Bradley, P, Harris, C, Cooper, J, Finch, C, Liderth, S, Quinn, A, Waddington, N, Fidler, K, Tagliavini, E, Donnelly, K, Abel, L, Brett, M, Digby, B, Gemmell, L, Hornsby, J, Macgoey, P, O’Neil, P, Price, R, Rodden, N, Rooney, K, Sundaram, R, Thomson, N, Flanagan, R, Hughes, G, Latham, S, Mckenna, E, Anderson, J, Hull, R, Rhead, K, Branney, D, Frankham, J, Pitts, S, White, N, Cristiano, D, Dormand, N, Farzad, Z, Gummadi, M, Liyanage, K, Salmi, S, Sloane, G, Varghese, M, Zborowski, A, Bean, S, Burt, K, Spivey, M, Eastgate-Jackson, C, Filipe, H, Martin, D, Maharajh, A, Garcia, S, De Neef, M, Lynch, C, Howe, G, Singh, J, Turner, K, Ellis, H, Stroud, N, Cherian, S, Cutler, S, Heron, A, Roynon-Reed, A, Williams, G, Richards, O, Cheema, Y, Ahmad, N, Barker, J, Bauchmuller, K, Bird, S, Cawthron, K, Harrington, K, Jackson, Y, Kibutu, F, Lenagh, B, Masuko, S, Raithatha, A, Wiles, M, Willson, J, Newell, H, Lye, A, Nwafor, L, Jarman, C, Rowland-Jones, S, Foote, D, Cole, J, Watson, J, Hesseldon, L, Macharia, I, Chetam, L, Ford, A, Housley, K, Milner, L, Hanratty, H, Trower, H, Phillips, P, Oxspring, S, Donne, B, Bevan, E, Martin, J, Trodd, D, Watson, G, Brown, C, Bunni, L, Jennings, C, Latif, M, Marshall, R, Subramanian, G, Bandla, N, Gellamucho, M, Davies, M, Trim, F, Eapen, B, Ahmed, C, Baines, B, Clamp, S, Colley, J, Haq, R, Hayes, A, Hulme, J, Joseph, S, Kumar, R, Maqsood, Z, Purewal, M, Chandler, B, Elliott, K, Mallinson, J, Turnbull, A, Dent, K, Horsley, E, Akhtar, M, Pearson, S, Potoczna, D, Spencer, S, Blakemore, H, Borislavova, B, Faulkner, B, Gendall, E, Goff, E, Hayes, K, Thomas, M, Worner, R, Smith, K, Stephens, D, Delgado, C, Dawson, D, Ding, L, Durrant, G, Ezeobu, O, Farnell-Ward, S, Harrison, A, Kanu, R, Leaver, S, Maccacari, E, Manna, S, Saluzzio, R, Queiroz, J, Samakomva, T, Sicat, C, Texeira, J, Da Gloria, E, Lisboa, A, Rawlins, J, Mathew, J, Kinch, A, Hurt, W, Shah, N, Clark, V, Thanasi, M, Yun, N, Patel, K, Crickmore, V, Debreceni, G, Wilkins, J, Nicol, L, Burn, I, Hambrook, G, Manso, K, Penn, R, Shanmugasundaram, P, Tebbutt, J, Thornton, D, Rostron, A, Roy, A, Woods, L, Cornell, S, Wakinshaw, F, Rogerson, K, Jarmain, J, Anderson, P, Archer, K, Austin, K, Davis, C, Durie, A, Kelsall, O, Thrush, J, Vigurs, C, Wood, H, Tranter, H, Cowley, N, Mcalindon, M, Digby, S, Low, E, Morgan, A, Cother, N, Rankin, T, Clayton, S, Mccurdy, A, Allibone, S, Mary-Genetu, R, Patel, A, Mac, A, Murphy, A, Mahjoob, P, Nazari, R, Worsley, L, Fagan, A, Mohamed Ali, I, Beaumont, K, Blunt, M, Coton, Z, Curgenven, H, Elsaadany, M, Fernandes, K, Ally, S, Rangarajan, H, Sarathy, V, Selvanayagam, S, Vedage, D, White, M, Fernandez-Roman, J, Hamilton, D, Johnson, E, Johnston, B, Martinez, M, Mulla, S, Waite, A, Waugh, V, Williams, K, Bemand, T, Black, E, Rosa, A, Howle, R, Jhanji, S, Baikady, R, Thomas, B, Halkes, M, Mercer, P, Thornton, L, West, J, Baird, T, Ruddy, J, Reece-Anthony, R, Birt, M, Cowton, A, Kay, A, Kent, M, Potts, K, Wilkinson, A, Naylor, S, Brown, E, Purvis, S, Davies, R, Duffin, D, Hill, H, Player, B, Thomas, E, Beith, C, Black, K, Clements, S, Morrison, A, Strachan, D, Clarkson, M, D’Sylva, S, Norman, K, Coventry, T, Fowler, S, Mcgregor, A, Brady, A, Chan, R, Mcivor, S, Prady, H, Whittle, H, Mathew, B, Clapham, M, Harper, R, Poultney, U, Rice, P, Mutch, R, Baird, Y, Butler, A, Chadbourn, I, Folkes, L, Fox, H, Gardner, A, Gomez, R, Hobden, G, King, K, Margarson, M, Martindale, T, Meadows, E, Raynard, D, Thirlwall, Y, Helm, D, Margalef, J, Greer, S, Shuker, K, Smuts, S, Duffield, J, Smith, O, Mallon, L, Claire, W, Birkinshaw, I, Carter, J, Howard, K, Ingham, J, Joy, R, Pearson, H, Roche, S, Scott, Z, Knights, E, Price, A, Thorpe, C, Abraheem, A, Bamford, P, Cawley, K, Dunmore, C, Faulkner, M, Girach, R, Jeffrey, H, Jones, R, London, E, Nagra, I, Nasir, F, Sainsbury, H, Smedley, C, Khade, R, Sundar, A, Tsinaslanidis, G, Behan, T, Burnett, C, Hatton, J, Heeney, E, Mitra, A, Newton, M, Pollard, R, Stead, R, Bough, L, Goodsell, J, Tutton, R, Williams, P, Williams, S, Winter-Goodwin, B, Auld, F, Donnachie, J, Edmond, I, Prentice, L, Runciman, N, Salutous, D, Symon, L, Todd, A, Turner, P, Short, A, Sweeney, L, Murdoch, E, Senaratne, D, Burns, K, Higham, A, Anderson, T, O’Malley, L, Rad, L, Rogers, N, Saunderson, P, Allison, K, Afolabi, D, Whitbread, J, Jones, D, Dore, R, Lankester, L, Nikitas, N, Wells, C, Stowe, B, Spencer, K, Cathcart, S, Duffy, K, Puxty, A, Puxty, K, Turner, L, Ireland, J, Semple, G, Barry, P, Hilltout, P, Evitts, J, Tyler, A, Waldron, J, Irvine, V, Shelley, B, Akinkugbe, O, Bamford, A, Beech, E, Belfield, H, Bell, M, Davies, C, Jones, G, Mchugh, T, Meghari, H, O’Neill, L, Ray, S, Tomas, A, Gorman, C, Gupta, A, Timlick, E, Brady, R, Bonner, S, Hugill, K, Jones, J, Liggett, S, Bashyal, A, Davidson, N, Hutton, P, Mckechnie, S, Flint, N, Rekha, P, Hales, D, Cruz, C, Gopal, S, Harris, N, Lake, V, Metherell, S, Radford, E, Clement, I, Gulati, A, Hays, C, Webster, K, Hudson, A, Webster, A, Stephenson, E, Mccormack, L, Slater, V, Nixon, R, Hanson, H, Fearby, M, Kelly, S, Bridgett, V, Robinson, P, Almaden-Boyle, C, Austin, P, Cabrelli, L, Casey, M, Chapman, S, Whyte, C, Brayne, A, Fisher, E, Jackson, P, Kaye, D, Love, N, Parkin, J, Tuckey, V, van Koutrik, L, Carter, S, Andrew, B, Findlay, L, Adams, K, Bruce, M, Connolly, K, Duncan, T, T. -Michael, H, Lindergard, G, Hey, S, Fox, C, Alfonso, J, Durrans, L, Guerin, J, Hruska, M, Eltayeb, A, Lamb, T, Hodgkiss, T, Cooper, L, Rothwell, J, Dennis, C, Srikaran, S, Sukha, A, Davies, K, O’Brien, L, Omar, Z, Perkins, E, Lewis, T, Sutherland, I, Brooke, H, Buckley, S, Suarez, J, Charlesworth, R, Hansson, K, Norris, J, Poole, A, Sandhu, R, Sloan, B, Smithson, E, Thirumaran, M, Wagstaff, V, Metcalfe, A, Camsooksai, J, Humphrey, C, Wadams, B, Death, Y, Adams, C, Agasou, A, Arden, T, Bowes, A, Boyle, P, Beekes, M, Button, H, Capps, N, Carnahan, M, Carter, A, Childs, D, Donaldson, D, Hard, K, Hurford, F, Hussain, Y, Javaid, A, Jose, S, Leigh, M, Martin, T, Millward, H, Motherwell, N, Rikunenko, R, Stickley, J, Summers, J, Ting, L, Tivenan, H, Tonks, L, Wilcox, R, Bokhari, M, Lucas, R, Mccormick, W, Ritzema, J, Sanderson, A, Wild, H, Baxter, N, Henderson, S, Kennedy-Hay, S, Rooney, L, Sim, M, Mccreath, G, Brunton, M, Caterson, J, Coles, H, Frise, M, Rai, S, Keating, L, Tilney, E, Bartley, S, Bhuie, P, Downes, C, Holding, K, Riches, K, Hilton, M, Hayman, M, Subramanian, D, Daniel, P, Zitter, L, Benyon, S, Marriott, S, Park, L, Keenan, S, Gordon, E, Quinn, H, Baines, K, Andrew, G, Barclay, L, Callaghan, M, Clark, S, Hope, D, Marshall, L, Mcculloch, C, Briton, K, Singleton, J, Birch, S, Simpson, K, Craig, J, Demetriou, C, Eckbad, C, Hierons, S, Howie, L, Mitchard, S, Ramos, L, Serrano-Ruiz, A, White, K, Kelly, F, Amin, V, Anastasescu, E, Anumakonda, V, Karthik, K, Kausar, R, Reid, K, Imeson-Wood, J, Bellini, A, Bryant, J, Pickard, A, Roe, N, Sowter, J, Howlett, A, Criste, K, Cusack, R, Golder, K, Golding, H, Jones, O, Leggett, S, Male, M, Marani, M, Prager, K, Williams, T, Roberts, B, Salmon, K, Gondo, P, Hadebe, B, Kayani, A, Masunda, B, Ahmed, A, Morris, A, Jakkula, S, Long, K, Whiteley, S, Wilby, E, Ogg, B, Moultrie, S, Odam, M, Bewley, J, Garland, Z, Grimmer, L, Gumbrill, B, Sweet, K, Webster, D, Efford, G, Bennett, S, Goodwin, E, Jackson, M, Kent, A, Tibke, C, Woodyatt, W, Zaki, A, Daniel, A, Finn, J, Bremmer, P, Allan, J, Geary, T, Houston, G, Meikle, A, O’Brien, P, Bell, D, Boyle, R, Douglas, K, Glass, L, Lee, E, Lennon, L, Rattray, A, Charnock, R, Mcfarland, D, Cosgrove, D, Attwood, B, Parsons, P, Carmody, S, Oblak, M, Popescu, M, Thankachen, M, Baruah, R, Morris, S, Ferguson, S, Shepherd, A, Altabaibeh, A, Alvaro, A, Gilbert, K, Ma, L, Mostoles, L, Parmar, C, Jetha, C, Booker, L, Pratley, A, Cosier, T, Millen, G, Schumacher, N, Weston, H, Rand, J, Alex, B, Bach, B, Barclay, W, Bogaert, D, Chand, M, Cooke, G, Docherty, A, Dunning, J, da Silva Filipe, A, Fletcher, T, Green, C, Harrison, E, Hiscox, J, Ijaz, S, Khoo, S, Lim, W, Mentzer, A, Merson, L, Noursadeghi, M, Moore, S, Palmarini, M, Paxton, W, Pollakis, G, Price, N, Rambaut, A, Robertson, D, Sancho-Shimizu, V, Scott, J, de Silva, T, Sigfrid, L, Solomon, T, Sriskandan, S, Stuart, D, Tedder, R, Thomson, E, Roger Thompson, A, Thwaites, R, Turtle, L, Palmieri, C, Swann, O, Zambon, M, Dumas, M, Griffin, J, Takats, Z, Chechi, K, Andrikopoulos, P, Osagie, A, Olanipekun, M, Liggi, S, Lewis, M, Correia, G, Sands, C, Takis, P, Maslen, L, Greenhalf, W, Shaw, V, Mcdonald, S, Ahmed, K, Ashworth, M, Asiimwe, I, Bakshi, S, Barlow, S, Booth, L, Brennan, B, Bullock, K, Catterall, B, Clark, J, Clarke, E, Cox, H, Dincarslan, O, Dunn, C, Dyer, P, Elliott, A, Evans, A, Finch, L, Fisher, L, Foster, T, Garcia-Dorival, I, Gunning, P, Hartley, C, Jensen, R, Khandaker, S, Kiy, R, Koukorava, C, Lake, A, Lant, S, Latawiec, D, Lavelle-Langham, L, Lefteri, D, Lett, L, Livoti, L, Mancini, M, Mcevoy, L, Mclauchlan, J, Metelmann, S, Miah, N, Middleton, J, Mitchell, J, Murphy, E, Penrice-Randal, R, Pilgrim, J, Prince, T, Reynolds, W, Ridley, P, Sales, D, Shears, R, Small, B, Subramaniam, K, Szemiel, A, Taggart, A, Tanianis-Hughes, J, Trochu, E, van Tonder, L, Wilcock, E, Zhang, J, Flaherty, L, Maziere, N, Cass, E, Carracedo, A, Carlucci, N, Holmes, A, Massey, H, Murphy, L, Wrobel, N, Mccafferty, S, Morrice, K, Maclean, A, Armstrong, R, Boz, C, Coutts, A, Cullum, L, Day, N, Donnelly, L, Duncan, E, Fawkes, A, Finernan, P, Gilchrist, T, Golightly, A, Hafezi, K, Law, D, Law, R, Law, S, Macgillivray, L, Mal, H, Mcmaster, E, Meikle, J, Oosthuyzen, W, Paterson, T, Stenhouse, A, Swets, M, Szoor-McElhinney, H, Taneski, F, Wackett, T, Ward, M, Weaver, J, Coyle, J, Gallagher, B, Lidstone-Scott, R, Schon, K, Furlong, A, Biggs, H, Griffiths, F, Andrews, E, Brickell, K, Smyth, M, Carson, G, Hardwick, H, Donohue, C, COVID-19 Host Genetics Initiative, Karjalainen, J., Neale, B.M., Daly, M., Ganna, A., Liao, R.G., Pathak, G.A., Andrews, S.J., Kanai, M., Veerapen, K., Fernandez-Cadenas, I., Schulte, E.C., Striano, P., Marttila, M., Minica, C., Marouli, E., Karim, M.A., Wendt, F.R., Savage, J., Sloofman, L., Butler-Laporte, G., Kim, H.N., Kanoni, S., Okada, Y., Byun, J., Han, Y., Uddin, M.J., Smith, G.D., Willer, C.J., Buxbaum, J.D., Mehtonen, J., Finucane, H., Cordioli, M., Martin, A.R., Zhou, W., Pasaniuc, B., Julienne, H., Aschard, H., Shi, H., Yengo, L., Polimanti, R., Ghoussaini, M., Schwartzentruber, J., Dunham, I., Chwialkowska, K., Francescatto, M., Trankiem, A., Balaconis, M.K., Davis, L., Lee, S., Priest, J., Renieri, A., Sankaran, V.G., van Heel, D., Deelen, P., Richards, J.B., Nakanishi, T., Biesecker, L., Kerchberger, V.E., Baillie, J.K., Mari, F., Bernasconi, A., Baillie, S.C., Canakoglu, A., Wolford, B., Faucon, A., Dutta, A.K., Schurmann, C., Harry, E., Birney, E., Nguyen, H., Nasir, J., Kaunisto, M., Solomonson, M., Dueker, N., Vadgama, N., Limou, S., Rahmouni, S., Mbarek, H., Darwish, D., Uddin, M.M., Albertos, R., Pérez-Tur, J., Li, R., Folkersen, L., Moltke, I., Koelling, N., Teumer, A., Kousathanas, A., Utrilla, A., Verdugo, R.A., Zárate, R., Medina-Gómez, C., Gómez-Cabrero, D., Carnero-Montoro, E., Cadilla, C.L., Moreno-Estrada, A., Garmendia, A., Moya, L., Sedaghati-Khayat, B., Boua, P.R., Favé, M.J., Francioli, L., Lemaçon, A., Migeotte, I., Patel, S., Varnai, R., Szentpeteri, J.L., Sipeky, C., Colombo, F., von Hohenstaufen, K., Lio, P., Vallerga, C., Wang, Q., Tanigawa, Y., Im, H., Han, C., Song, H., Lim, J., Lee, Y., Kim, S., Im, S., Atanasovska, B., Ahmad, H.F., Boer, C., Jansen, P., Franke, L., Kaja, E., Pasko, D., Kennis-Szilagyi, I., Kornilov, S.A., Prijatelj, V., Prokić, I., Sivanadhan, I., Perumal, S., Esmaeeli, S., Pearson, N.M., Auton, A., Shelton, J.F., Shastri, A.J., Filshtein-Sonmez, T., Coker, D., Symons, A., Esparza-Gordillo, J., Aslibekyan, S., O'Connell, J., Ye, C., Weldon, C.H., Perera, M., O'Leary, K., Tuck, M., O'Brien, T., Meltzer, D., O'Donnell, P., Nutescu, E., Yang, G., Alarcon, C., Herrmann, S., Mazurek, S., Banagan, J., Hamidi, Z., Barbour, A., Raffat, N., Moreno, D., Friedman, P., Ferwerda, B., van de Beek, D., Brouwer, M.C., Vlaar, APJ, Wiersinga, W.J., Posthuma, D., Tissink, E., Koos Zwinderman, A.H., Uffelmann, E., van Agtmael, M., Algera, A.G., van Baarle, F., Bax, D., Beudel, M., Jan Bogaard, H., Bomers, M., Bonta, P.I., Bos, L., Botta, M., de Brabander, J., de Bree, G., de Bruin, S., Bugiani, M., Bulle, E., Chouchane, O., Cloherty, A., Dongelmans, D., Elbers, P., Fleuren, L., Geerlings, S., Geerts, B., Geijtenbeek, T., Girbes, A., Goorhuis, B., Grobusch, M.P., Hafkamp, F., Hagens, L., Hamann, J., Harris, V., Hemke, R., Hermans, S.M., Heunks, L., Hollmann, M., Horn, J., Hovius, J.W., de Jong, M.D., Koning, R., van Mourik, N., Nellen, J., Nossent, E.J., Paulus, F., Peters, E., van der Poll, T., Preckel, B., Prins, J.M., Raasveld, J., Reijnders, T., Schinkel, M., Schultz, M.J., Schuurman, A., Sigaloff, K., Smit, M., Stijnis, C.S., Stilma, W., Teunissen, C., Thoral, P., Tsonas, A., van der Valk, M., Veelo, D., de Vries, H., van Vugt, M., Wouters, D., Minnaar, R.P., Kromhout, A., van Uffelen, KWJ, Wolterman, R.A., Roberts, G., Park, D., Ball, C.A., Coignet, M., McCurdy, S., Knight, S., Partha, R., Rhead, B., Zhang, M., Berkowitz, N., Gaddis, M., Noto, K., Ruiz, L., Pavlovic, M., Hong, E.L., Rand, K., Girshick, A., Guturu, H., Baltzell, A.H., Guntz, J., Beguin, Y., Pigazzini, S., Nkambule, L., Bouysran, Y., Busson, A., Peyrassol, X., Wilkin, F., Pichon, B., Smits, G., Vandernoot, I., Goffard, J.C., Georges, M., Moutschen, M., Misset, B., Darcis, G., Guiot, J., Jadot, L., Azarzar, S., Dellot, P., Gofflot, S., Claassen, S., Bertrand, A., Parzibut, G., Clarinval, M., Moermans, C., Malaise, O., El Kandoussi, K., Thonon, R., Huynen, P., Mesdagh, A., Melo, S., Jacques, N., Di Valentin, E., Giroule, F., Collignon, A., Radermecker, C., Lebrun, M., Perée, H., Latour, S., Barada, O., Sanchez, J., Josse, C., Boujemla, B., Meunier, M., Mariavelle, E., Anania, S., Gazon, H., Juszczak, D., Fadeur, M., Camby, S., Meuris, C., Thys, M., Jacques, J., Henket, M., Léonard, P., Frippiat, F., Giot, J.B., Sauvage, A.S., Von Frenckell, C., Mni, M., Wéry, M., Staderoli, A., Belhaj, Y., Lambermont, B., Morrison, D.R., Mooser, V., Forgetta, V., Ghosh, B., Laurent, L., Belisle, A., Henry, D., Abdullah, T., Adeleye, O., Mamlouk, N., Kimchi, N., Afrasiabi, Z., Rezk, N., Vulesevic, B., Bouab, M., Guzman, C., Petitjean, L., Tselios, C., Xue, X., Afilalo, J., Afilalo, M., Oliveira, M., Brenner, B., Brassard, N., Durand, M., Schurr, E., Lepage, P., Ragoussis, J., Auld, D., Chassé, M., Kaufmann, D.E., Lathrop, G.M., Adra, D., Davis, L.K., Cox, N.J., Below, J.E., Sealock, J.M., Faucon, A.B., Shuey, M.M., Polikowsky, H.G., Petty, L.E., Shaw, D.M., Chen, H.H., Zhu, W., Ludwig, K.U., Schröder, J., Maj, C., Rolker, S., Nöthen, M.M., Fazaal, J., Keitel, V., Jensen, B.O., Feldt, T., Kurth, I., Marx, N., Dreher, M., Pink, I., Cornberg, M., Illig, T., Lehmann, C., Schommers, P., Augustin, M., Rybniker, J., Knopp, L., Eggermann, T., Volland, S., Altmüller, J., Berger, M.M., Brenner, T., Hinney, A., Witzke, O., Bals, R., Herr, C., Ludwig, N., Walter, J., Fuchsberger, C., Pattaro, C., De Grandi, A., Pramstaller, P., Emmert, D., Melotti, R., Foco, L., Mascalzoni, D., Gögele, M., Domingues, F., Hicks, A., Gignoux, C.R., Wicks, S.J., Crooks, K., Barnes, K.C., Daya, M., Shortt, J., Rafaels, N., Chavan, S., Goldstein, D.B., Kiryluk, K., Sengupta, S., Chung, W., Reilly, M.P., Khan, A., Wang, C., Povysil, G., Bhardwaj, N., Gharavi, A.G., Ionita-Laza, I., Shang, N., O'Byrne, S.M., Nandakumar, R., Menon, A., So, Y.S., Hod, E., Pendrick, D., Park, S.K., Kim, H.L., Kang, C.K., Lee, H.J., Song, K.H., Jae Yoon, K., Paik, N.J., Seok, W., Yoon, H., Joo, E.J., Chang, Y., Ryu, S., Park, W.B., Su Park, J., Un Park, K., Ham, S.Y., Jung, J., Kim, E.S., Kim, H.B., Ellinghaus, D., Degenhardt, F., Cáceres, M., Juzenas, S., Lenz, T.L., Albillos, A., Julià, A., Heidecker, B., Garcia, F., Kurth, F., Tran, F., Hanses, F., Zoller, H., Holter, J.C., Fernández, J., Sander, L.E., Rosenstiel, P., Koehler, P., de Cid, R., Asselta, R., Schreiber, S., Hehr, U., Prati, D., Baselli, G., Valenti, L., Bujanda, L., Banales, J.M., Duga, S., D'Amato, M., Romero-Gómez, M., Buti, M., Invernizzi, P., Franke, A., Hov, J.R., Karlsen, T.H., Folseraas, T., Maya-Miles, D., Teles, A., Azuure, C., Wacker, E.M., Uellendahl-Werth, F., ElAbd, H., Arora, J., Lerga-Jaso, J., Wienbrandt, L., Rühlemann, M.C., Wendorff, M., Vadla, M.S., Lenning, O.B., Özer, O., Myhre, R., Raychaudhuri, S., Tanck, A., Gassner, C., Hemmrich-Stanisak, G., Kässens, J., Figuera Basso, M.E., Schulzky, M., Wittig, M., Braun, N., Wesse, T., Albrecht, W., Yi, X., Ortiz, A.B., Chercoles, A.G., Ruiz, A., Mantovani, A., Holten, A.R., Mayer, A., Cherubini, A., Protti, A., Aghemo, A., Gerussi, A., Ramirez, A., Braun, A., Barreira, A., Lleo, A., Kildal, A.B., Glück, A., Nolla, A.C., Latiano, A., Dyrhol-Riise, A.M., Muscatello, A., Voza, A., Rando-Segura, A., Solier, A., Karina, B., Cortes, B., Mateos, B., Nafria-Jimenez, B., Schaefer, B., Bellinghausen, C., Ferrando, C., Quereda, C., Skurk, C., Thibeault, C., Spinner, C.D., Lange, C., Hu, C., Cappadona, C., Bianco, C., Sancho, C., Lihaug Hoff, D.A., Galimberti, D., Jiménez, D., Pestaña, D., Toapanta, D., Azzolini, E., Scarpini, E., Helbig, E.T., Urrechaga, E., Paraboschi, E.M., Pontali, E., Reverter, E., Navas, E., Arana, E., Sánchez, F.G., Ceriotti, F., Malvestiti, F., Mesonero, F., Pezzoli, G., Lamorte, G., Neb, H., My, I., Hernández, I., de Rojas, I., Galván-Femenia, I., Heyckendorf, J., Badia, J.R., Schneider, J., Goikoetxea, J., Kraft, J., Müller, K.E., Gaede, K.I., Garcia-Etxebarria, K., Tonby, K., Heggelund, L., Izquierdo-Sanchez, L., Sumoy, L., Lippert, L.J., Terranova, L., Garbarino, L., Téllez, L., Roade, L., Ostadreza, M., Intxausti, M., Kogevinas, M., Gutiérrez-Stampa, M.A., Vehreschild, MJGT, Marquié, M., Castoldi, M., Cecconi, M., Boada, M., Seilmaier, M.J., Mazzocco, M., Rodríguez-Gandía, M., Ayo, N.I., Blay, N., Martínez, N., Cornely, O.A., Palmieri, O., Tentorio, P., Rodrigues, P.M., España, P.P., Hoffmann, P., Bacher, P., Suwalski, P., de Pablo, R., Nieto, R., Badalamenti, S., Ciesek, S., Bombace, S., Wilfling, S., Brunak, S., Heilmann-Heimbach, S., Ripke, S., Bahmer, T., Landmesser, U., Protzer, U., Rimoldi, V., Skogen, V., Andrade, V., Moreno, V., Poller, W., Farre, X., Wang, X., Khodamoradi, Y., Karadeniz, Z., de Salazar, A., Palom, A., Garcia-Fernandez, A.E., Blanco-Grau, A., Zanella, A., Bandera, A., Nebel, A., Biondi, A., Caballero-Garralda, A., Gori, A., Lind, A., Fracanzani, A.L., Peschuck, A., Pesenti, A., de la Horra, C., Milani, C., Paccapelo, C., Angelini, C., Cea, C., Muñiz-Diaz, E., Sandoval, E., Calderón, E.J., Solligård, E., Aziz, F., Martinelli-Boneschi, F., Peyvandi, F., Blasi, F., Medrano, F.J., Rodriguez-Frias, F., Müller, F., Grasselli, G., Costantino, G., Cardamone, G., Foti, G., Matullo, G., Kurihara, H., Afset, J.E., Damås, J.K., Ampuero, J., Martín, J., Erdmann, J., Bergan, J., Goerg, S., Ferrusquía-Acosta, J., Quero, J.H., Delgado, J., Guerrero, J.M., Risnes, K., Bettini, L.R., Moreira, L., Gustad, L.T., Santoro, L., Scudeller, L., Riveiro-Barciela, M., Schaefer, M., Carrabba, M., Valsecchi, M.G., Hernandez-Tejero, M., Acosta-Herrera, M., D'Angiò, M., Baldini, M., Cazzaniga, M., Ciccarelli, M., Bocciolone, M., Miozzo, M., Chueca, N., Montano, N., Faverio, P., Preatoni, P., Bonfanti, P., Omodei, P., Castro, P., Ferrer, R., Gualtierotti, R., Gallego-Durán, R., Morilla, R., Haider, S., Marsal, S., Aneli, S., Pelusi, S., Bosari, S., Aliberti, S., Dudman, S., Zheng, T., Pumarola, T., Cejudo, T.G., Monzani, V., Friaza, V., Peter, W., Dopazo, X., May, S., Grimsrud, M.M., Gudbjartsson, D.F., Stefansson, K., Sulem, P., Sveinbjornsson, G., Melsted, P., Norddahl, G., Swerford Moore, K.H., Thorsteinsdottir, U., Holm, H., Alarcón-Riquelme, M.E., Bernardo, D., Martínez-Bueno, M., Rello, S.R., Magi, R., Milani, L., Metspalu, A., Laisk, T., Läll, K., Lepamets, M., Esko, T., Reimann, E., Naaber, P., Laane, E., Pesukova, J., Peterson, P., Kisand, K., Tabri, J., Allos, R., Hensen, K., Starkopf, J., Ringmets, I., Tamm, A., Kallaste, A., Alavere, H., Metsalu, K., Puusepp, M., Kristiansson, K., Koskelainen, S., Perola, M., Donner, K., Kivinen, K., Palotie, A., Bochud, P.Y., Boillat, N., Nussle, S.G., Albrich, W., Pagani, J.L., Zu Bentrup, F.M., Viollet, R.M., Kampouri, E.E., Meuwly, J.Y., D'Acremont, V., Younes, S.E., Albrich, W.C., O'Mahony, L., Kleger, G.R., Kahlert, C.R., Negro, T.R., Carreras, A., Galván-Femenía, I., Farré, X., Cortés, B., Mercader, J.M., Guindo-Martinez, M., Torrents, D., Garcia-Aymerich, J., Castaño-Vinyals, G., Dobaño, C., Gori, M., Mondelli, M.U., Castelli, F., Vaghi, M., Rusconi, S., Montagnani, F., Bargagli, E., Franchi, F., Mazzei, M.A., Cantarini, L., Tacconi, D., Feri, M., Scala, R., Spargi, G., Nencioni, C., Bandini, M., Caldarelli, G.P., Spagnesi, M., Canaccini, A., Ognibene, A., D'Arminio Monforte, A., Girardis, M., Antinori, A., Francisci, D., Schiaroli, E., Scotton, P.G., Panese, S., Scaggiante, R., Monica, M.D., Capasso, M., Fiorentino, G., Castori, M., Aucella, F., Di Biagio, A., Masucci, L., Valente, S., Mandalà, M., Zucchi, P., Giannattasio, F., Coviello, D.A., Mussini, C., Bosio, G., Tavecchia, L., Crotti, L., Rizzi, M., La Rovere, M.T., Sarzi-Braga, S., Bussotti, M., Ravaglia, S., Artuso, R., Perrella, A., Romani, D., Bergomi, P., Catena, E., Vincenti, A., Ferri, C., Grassi, D., Pessina, G., Tumbarello, M., Di Pietro, M., Sabrina, R., Luchi, S., Barbieri, C., Acquilini, D., Andreucci, E., Paciosi, F., Segala, F.V., Tiseo, G., Falcone, M., Lista, M., Poscente, M., De Vivo, O., Petrocelli, P., Guarnaccia, A., Baroni, S., Perticaroli, V., Furini, S., Dei, S., Benetti, E., Picchiotti, N., Sanarico, M., Ceri, S., Pinoli, P., Raimondi, F., Biscarini, F., Stella, A., Bergomi, M., Zguro, K., Capitani, K., Tanfoni, M., Fallerini, C., Daga, S., Baldassarri, M., Fava, F., Frullanti, E., Valentino, F., Doddato, G., Giliberti, A., Tita, R., Amitrano, S., Bruttini, M., Croci, S., Meloni, I., Mencarelli, M.A., Lo Rizzo, C., Pinto, A.M., Beligni, G., Tommasi, A., Di Sarno, L., Palmieri, M., Carriero, M.L., Alaverdian, D., Iuso, N., Inchingolo, G., Busani, S., Bruno, R., Vecchia, M., Belli, M.A., Mantovani, S., Ludovisi, S., Quiros-Roldan, E., Antoni, M.D., Zanella, I., Siano, M., Emiliozzi, A., Fabbiani, M., Rossetti, B., Zanelli, G., Bergantini, L., D'Alessandro, M., Cameli, P., Bennet, D., Anedda, F., Marcantonio, S., Scolletta, S., Guerrini, S., Conticini, E., Frediani, B., Spertilli, C., Donati, A., Guidelli, L., Corridi, M., Croci, L., Piacentini, P., Desanctis, E., Cappelli, S., Verzuri, A., Anemoli, V., Pancrazi, A., Lorubbio, M., Merlini, E., Miraglia, F.G., Venturelli, S., Cossarizza, A., Vergori, A., Gabrieli, A., Riva, A., Andretta, F., Gatti, F., Parisi, S.G., Baratti, S., Piscopo, C., Russo, R., Andolfo, I., Iolascon, A., Carella, M., Merla, G., Squeo, G.M., Raggi, P., Marciano, C., Perna, R., Bassetti, M., Sanguinetti, M., Giorli, A., Salerni, L., Parravicini, P., Menatti, E., Trotta, T., Coiro, G., Lena, F., Martinelli, E., Mancarella, S., Gabbi, C., Maggiolo, F., Ripamonti, D., Bachetti, T., Suardi, C., Parati, G., Bottà, G., Di Domenico, P., Rancan, I., Bianchi, F., Colombo, R., van Heel, D.A., Hunt, K.A., Trembath, R.C., Huang, Q.Q., Martin, H.C., Mason, D., Trivedi, B., Wright, J., Finer, S., Griffiths, C.J., Akhtar, S., Anwar, M., Arciero, E., Ashraf, S., Breen, G., Chung, R., Curtis, C.J., Chowdhury, M., Colligan, G., Deloukas, P., Durham, C., Griffiths, C., Hurles, M., Hussain, S., Islam, K., Lavery, C., Lee, S.H., Lerner, R., MacArthur, D., MacLaughlin, B., Martin, H., Miah, S., Newman, B., Safa, N., Tahmasebi, F., Smith, A.V., Boughton, A.P., Li, K.W., LeFaive, J., Annis, A., Jannes, C.E., Krieger, J.E., Pereira, A.C., Velho, M., Marques, E., Lima, I.R., Tada, M.T., Valino, K., McCarthy, M., Rosenberger, C., Lee, J.E., Chang, D., Hammer, C., Hunkapiller, J., Mahajan, A., Pendergrass, S., Sucheston-Campbell, L., Yaspan, B., Lee, H.S., Shin, E., Jang, H.Y., Kym, S., Kim, Y.S., Jeong, H., Kwon, K.T., Kim, S.W., Kim, J.Y., Jang, Y.R., Kim, H.A., Lee, J.Y., Choe, K.W., Kang, Y.M., Jee, S.H., Jung, K.J., Parikh, V., Ashley, E., Wheeler, M., Rivas, M., Bustamante, C., Pinksy, B., Febbo, P., Farh, K., Schroth, G.P., deSouza, F., Dalton, K., Christle, J., Deboever, C., Szalma, S., Rubinacci, S., Delaneau, O., Gorzynski, J., de Jong, H., Sutton, S., Youlton, N., Joshi, R., Jimenez-Morales, D., Hughes, C., Amar, D., Ioannidis, A., Hershman, S., Kirillova, A., Seo, K., Huang, Y., Shoura, M., Hammond, N., Watson, N., Raja, A., Huang, C., Sahoo, M., Wang, H., Zhen, J., Rakitko, A., Ilinsky, V., Yermakovich, D., Popov, I., Chernitsov, A., Kovalenko, E., Krasnenko, A., Plotnikov, N., Stetsenko, I., Kim, A., Cirulli, E.T., Schiabor Barrett, K.M., Bolze, A., White, S., Washington, N.L., Lu, J.T., Riffle, S., Tanudjaja, F., Ramirez, J.M., Leonetti, N., Neveux, I., Dabe, S., Grzymski, J.J., Esteban Miñano, J.I., Aguirre, L.A., López-Collazo, E., de la Mata Pazos, M., Cerrato, L., Lozano-Rodríguez, R., Avendaño-Ortiz, J., Arcos, V.T., Montalbán-Hernández, K.M., Quiroga, J.V., Pascual-Iglesias, A., Maroun-Eid, C., Martín-Quirós, A., Namkoong, H., Imoto, S., Katayama, K., Fukunaga, K., Kitagawa, Y., Sato, T., Hasegawa, N., Kumanogoh, A., Kimura, A., Ai, M., Tokunaga, K., Kanai, T., Miyano, S., Ogawa, S., Edahiro, R., Sonehara, K., Shirai, Y., Ishii, M., Kabata, H., Masaki, K., Kamata, H., Ikemura, S., Chubachi, S., Okamori, S., Terai, H., Tanaka, H., Morita, A., Lee, H., Asakura, T., Sasaki, J., Morisaki, H., Uwamino, Y., Nanki, K., Mikami, Y., Tomono, K., Kato, K., Matsuda, F., Takahashi, M., Hizawa, N., Takeda, Y., Hirata, H., Shiroyama, T., Miyawaki, S., Suzuki, K., Maeda, Y., Nii, T., Noda, Y., Niitsu, T., Adachi, Y., Enomoto, T., Amiya, S., Hara, R., Takahashi, K., Anzai, T., Hasegawa, T., Ito, S., Koike, R., Endo, A., Uchimura, Y., Miyazaki, Y., Honda, T., Tateishi, T., Tohda, S., Ichimura, N., Sonobe, K., Sassa, C., Nakajima, J., Nannya, Y., Omae, Y., Harada, N., Hiki, M., Takagi, H., Nakamura, A., Tagaya, E., Kawana, M., Arimura, K., Ishiguro, T., Takayanagi, N., Isono, T., Takaku, Y., Takano, K., Anan, R., Nakajima, Y., Nakano, Y., Nishio, K., Ueda, S., Hayashi, R., Tateno, H., Hase, I., Yoshida, S., Suzuki, S., Mitamura, K., Saito, F., Ueda, T., Azuma, M., Nagasaki, T., Yasui, Y., Hasegawa, Y., Mutoh, Y., Yoshiyama, T., Shoko, T., Kojima, M., Adachi, T., Ishikawa, M., Watanabe, K., Manabe, T., Ito, F., Fukui, T., Funatsu, Y., Koh, H., Hirai, Y., Kawashima, H., Narita, A., Niwa, K., Sekikawa, Y., Yoshiya, K., Yoshihara, T., Suzuki, Y., Nakayama, S., Masuzawa, K., Nishi, K., Nishitsuji, M., Tani, M., Inoue, T., Hirano, T., Kobayashi, K., Miyazawa, N., Kimura, Y., Sado, R., Ogura, T., Kitamura, H., Murohashi, K., Nakachi, I., Baba, R., Arai, D., Fuke, S., Saito, H., Kuwahara, N., Fujiwara, A., Okada, T., Baba, T., Noda, J., Mashimo, S., Yagi, K., Shiomi, T., Hashiguchi, M., Odani, T., Mochimaru, T., Oyamada, Y., Mori, N., Izumi, N., Nagata, K., Taki, R., Murakami, K., Yamada, M., Sugiura, H., Hayashi, K., Shimizu, T., Gon, Y., Fujitani, S., Tsuchida, T., Yoshida, T., Kagaya, T., Kita, T., Sakagami, S., Kimizuka, Y., Kawana, A., Nakamura, Y., Ishikura, H., Takata, T., Kikuchi, T., Taniyama, D., Nakamura, M., Kodama, N., Kaneyama, Y., Maeda, S., Nagasaki, Y., Okamoto, M., Ishihara, S., Ito, A., Chihara, Y., Takeuchi, M., Onoi, K., Hashimoto, N., Wakahara, K., Ando, A., Masuda, M., Wakabayashi, A., Watanabe, H., Sageshima, H., Nakada, T.A., Abe, R., Shimada, T., Kawamura, K., Ichikado, K., Nishiyama, K., Yamasaki, M., Hashimoto, S., Kusaka, Y., Ohba, T., Isogai, S., Takada, M., Kanda, H., Komase, Y., Sano, F., Asano, K., Oguma, T., Harada, M., Takahashi, T., Shibusawa, T., Abe, S., Kono, Y., Togashi, Y., Izumo, T., Inomata, M., Awano, N., Ogata, T., Kanehiro, A., Ozaki, S., Fuchimoto, Y., Ogura, S., Yoshida, K., Beppu, S., Fukuyama, S., Eriguchi, Y., Yonekawa, A., Inoue, Y., Yamagata, K., Chiba, S., Narumoto, O., Nagai, H., Ooshima, N., Motegi, M., Sagara, H., Tanaka, A., Ohta, S., Shibata, Y., Tanino, Y., Sato, Y., Yamada, Y., Hashino, T., Shinoki, M., Iwagoe, H., Imamura, T., Umeda, A., Shimada, H., Endo, M., Hayashi, S., Nakano, S., Yatomi, M., Maeno, T., Ishii, T., Utsugi, M., Ono, A., Kanaoka, K., Ihara, S., Komuta, K., Boezen, M., Claringbould, A., Lopera, E., Warmerdam, R., Vonk, J.M., van Blokland, I., Lanting, P., Ori, APS, Obeidat, M., Hernández Cordero, A.I., Sin, D.D., Bossé, Y., Joubert, P., Hao, K., Nickle, D., Timens, W., van den Berge, M., Feng, Y.A., Mercader, J., Weiss, S.T., Karlson, E.W., Smoller, J.W., Murphy, S.N., Meigs, J.B., Woolley, A.E., Green, R.C., Perez, E.F., Zöllner, S., Wang, J., Beck, A., Sloofman, L.G., Ascolillo, S., Sebra, R.P., Collins, B.L., Levy, T., Sealfon, S.C., Jordan, D.M., Thompson, R.C., Gettler, K., Chaudhary, K., Belbin, G.M., Preuss, M., Hoggart, C., Choi, S., Underwood, S.J., Salib, I., Britvan, B., Keller, K., Tang, L., Peruggia, M., Hiester, L.L., Niblo, K., Aksentijevich, A., Labkowsky, A., Karp, A., Zlatopolsky, M., Zyndorf, M., Charney, A.W., Beckmann, N.D., Schadt, E.E., Abul-Husn, N.S., Cho, J.H., Itan, Y., Kenny, E.E., Loos, RJF, Nadkarni, G.N., Do, R., O'Reilly, P., Huckins, L.M., Ferreira, MAR, Abecasis, G.R., Leader, J.B., Cantor, M.N., Justice, A.E., Carey, D.J., Chittoor, G., Josyula, N.S., Kosmicki, J.A., Horowitz, J.E., Baras, A., Gass, M.C., Yadav, A., Mirshahi, T., Jan Hottenga, J., Bartels, M., de Geus, EJC, Nivard, M.G., Verma, A., Ritchie, M.D., Rader, D., Li, B., Verma, S.S., Lucas, A., Bradford, Y., Zara, F., Salpietro, V., Scala, M., Iacomino, M., Scudieri, P., Bocciardi, R., Minetti, C., Vari, M.S., Rahier, J.F., Giorgio, E., Carli, D., Louis, E., Bulik, C.M., Landén, M., Brusco, A., Ferrero, G.B., Madia, F., Fundín, B., Ismail, S.I., Saad, C., Al-Sarraj, Y., Badji, R.M., Al-Muftah, W., Al Thani, A., Afifi, N., Klovins, J., Rovite, V., Rescenko, R., Peculis, R., Ustinova, M., Zeberg, H., Frithiof, R., Hultström, M., Lipcsey, M., Johnson, R., Geschwind, D.H., Freimer, N., Butte, M.J., Ding, Y., Chiu, A., Chang, T.S., Boutros, P., Moutsianas, L., Caulfield, M.J., Scott, R.H., Walker, S., Stuckey, A., Odhams, C.A., Rhodes, D., Fowler, T., Rendon, A., Chan, G., Arumugam, P., Karczewski, K.J., Wilson, D.J., Spencer, C.A., Crook, D.W., Wyllie, D.H., O'Connell, A.M., Atkinson, E.G., Tsuo, K., Baya, N., Turley, P., Gupta, R., Walters, R.K., Palmer, D.S., Sarma, G., Cheng, N., Lu, W., Churchhouse, C., Goldstein, J.I., King, D., Seed, C., Daly, M.J., Bryant, S., Satterstrom, F.K., Band, G., Earle, S.G., Lin, S.K., Arning, N., Armstrong, J., Rudkin, J.K., Callier, S., Cusick, C., Soranzo, N., Zhao, J.H., Danesh, J., Di Angelantonio, E., Butterworth, A.S., Sun, Y.V., Huffman, J.E., Cho, K., O'Donnell, C.J., Tsao, P., Gaziano, J.M., Peloso, G., Ho, Y.L., Mian, M., Scaggiante, F., Chang, X., Glessner, J.R., Hakonarson, H., McGuigan, P.J., Prockter Moore, L.S., Vizcaychipi, M.P., Hall, K., Campbell, A., Nichol, A., Ward, G., Page, V.J., Semple, M.G., Adeniji, K., Agranoff, D., Agwuh, K., Ail, D., Aldera, E.L., Alegria, A., Angus, B., Ashish, A., Atkinson, D., Bari, S., Barlow, G., Barnass, S., Barrett, N., Bassford, C., Basude, S., Baxter, D., Beadsworth, M., Bernatoniene, J., Berridge, J., Best, N., Bothma, P., Chadwick, D., Brittain-Long, R., Bulteel, N., Burden, T., Burtenshaw, A., Caruth, V., Chambler, D., Chee, N., Child, J., Chukkambotla, S., Clark, T., Collini, P., Cosgrove, C., Cupitt, J., Cutino-Moguel, M.T., Dark, P., Dawson, C., Dervisevic, S., Donnison, P., Douthwaite, S., Drummond, A., DuRand, I., Dushianthan, A., Dyer, T., Evans, C., Eziefula, C., Fegan, C., Finn, A., Fullerton, D., Garg, S., Garg, A., Gkrania-Klotsas, E., Godden, J., Goldsmith, A., Graham, C., Hardy, E., Hartshorn, S., Harvey, D., Havalda, P., Hawcutt, D.B., Hobrok, M., Hodgson, L., Hormis, A., Jacobs, M., Jain, S., Jennings, P., Kaliappan, A., Kasipandian, V., Kegg, S., Kelsey, M., Kendall, J., Kerrison, C., Kerslake, I., Koch, O., Koduri, G., Koshy, G., Laha, S., Laird, S., Larkin, S., Leiner, T., Lillie, P., Limb, J., Linnett, V., Little, J., Lyttle, M., MacMahon, M., MacNaughton, E., Mankregod, R., Masson, H., Matovu, E., McCullough, K., McEwen, R., Meda, M., Mills, G.H., Minton, J., Ward, K., Mirfenderesky, M., Mohandas, K., Mok, Q., Moon, J., Moore, E., Morgan, P., Morris, C., Mortimore, K., Moses, S., Mpenge, M., Mulla, R., Murphy, M., Nagel, M., Nagarajan, T., Nelson, M., O'Shea, M.K., Otahal, I., Ostermann, M., Pais, M., Panchatsharam, S., Papakonstantinou, D., Paraiso, H., Patel, B., Pattison, N., Pepperell, J., Peters, M., Phull, M., Pintus, S., Pooni, J.S., Post, F., Price, D., Prout, R., Rae, N., Reschreiter, H., Reynolds, T., Richardson, N., Roberts, M., Roberts, D., Rose, A., Rousseau, G., Ryan, B., Saluja, T., Shah, A., Shanmuga, P., Sharma, A., Shawcross, A., Sizer, J., Shankar-Hari, M., Smith, R., Snelson, C., Spittle, N., Staines, N., Stambach, T., Stewart, R., Subudhi, P., Szakmany, T., Tatham, K., Thomas, J., Thompson, C., Thompson, R., Tridente, A., Tupper-Carey, D., Twagira, M., Ustianowski, A., Vallotton, N., Vincent-Smith, L., Visuvanathan, S., Vuylsteke, A., Waddy, S., Wake, R., Walden, A., Welters, I., Whitehouse, T., Whittaker, P., Whittington, A., Papineni, P., Wijesinghe, M., Williams, M., Wilson, L., Cole, S., Winchester, S., Wiselka, M., Wolverson, A., Wooton, D.G., Workman, A., Yates, B., Young, P., Beale, R., Bretherick, A.D., Clohisey, S., Fourman, M.H., Furniss, J., Gountouna, E., Grimes, G., Haley, C., Harrison, D., Hayward, C., Keating, S., Klaric, L., Klenerman, P., Law, A., Meynert, A.M., Millar, J., Pairo-Castineira, E., Parkinson, N., Ponting, C.P., Porteous, D.J., Rawlik, K., Richmond, A., Rowan, K., Russell, C.D., Shen, X., Shih, B., Tenesa, A., Vitart, V., Wang, B., Wilson, J.F., Wu, Y., Yang, J., Yang, Z., Zechner, M., Zhai, R., Zheng, C., Norman, L., Pius, R., Drake, T.M., Fairfield, C.J., Knight, S.R., Mclean, K.A., Murphy, D., Shaw, C.A., Dalton, J., Girvan, M., Saviciute, E., Roberts, S., Harrison, J., Marsh, L., Connor, M., Halpin, S., Jackson, C., Gamble, C., Leeming, G., Wham, M., Hendry, R., Scott-Brown, J., Begg, C., Hinds, C., Wai Ho, A.Y., Horby, P.W., Knight, J., Ling, L., Maslove, D., McAuley, D., Montgomery, H., Openshaw, PJM, Summers, C., Walsh, T., Armstrong, L., Bates, H., Dooks, E., Farquhar, F., Hairsine, B., McParland, C., Packham, S., Alldis, Z., Astin-Chamberlain, R., Bibi, F., Biddle, J., Blow, S., Bolton, M., Borra, C., Bowles, R., Burton, M., Choudhury, Y., Collier, D., Cox, A., Easthope, A., Ebano, P., Fotiadis, S., Gurasashvili, J., Halls, R., Hartridge, P., Kallon, D., Kassam, J., Lancoma-Malcolm, I., Matharu, M., May, P., Mitchelmore, O., Newman, T., Patel, M., Pheby, J., Pinzuti, I., Prime, Z., Prysyazhna, O., Shiel, J., Taylor, M., Tierney, C., Wood, S., Zak, A., Zongo, O., Forsey, M., Nicholson, A., Riches, J., Vertue, M., Wasson, C., Finn, S., Green, J., Collins, E., King, B., Grauslyte, L., Hussain, M., Pogreban, T., Rosaroso, L., Salciute, E., Franke, G., Wong, J., George, A., Akeroyd, L., Bano, S., Bromley, M., Gurr, L., Lawton, T., Morgan, J., Sellick, K., Warren, D., Wilkinson, B., McGowan, J., Ledgard, C., Stacey, A., Pye, K., Bellwood, R., Bentley, M., Loosley, R., McGuinness, H., Tench, H., Wolf-Roberts, R., Gibson, S., Lyle, A., McNeela, F., Radhakrishnan, J., Hughes, A., Ali, A., Brady, M., Dale, S., Dance, A., Gledhill, L., Greig, J., Hanson, K., Holdroyd, K., Home, M., Kelly, D., Kitson, R., Matapure, L., Melia, D., Mellor, S., Nortcliffe, T., Pinnell, J., Robinson, M., Shaw, L., Shaw, R., Thomis, L., Wilson, A., Wood, T., Bayo, L.A., Merwaha, E., Ishaq, T., Hanley, S., Antcliffe, D., Banach, D., Brett, S., Coghlan, P., Fernandez, Z., Gordon, A., Rojo, R., Arias, S.S., Templeton, M., Jha, R., Krishnamurthy, V., Lim, L., Bi, R., Scholefield, B., Ashton, L., Williams, A., Cheyne, C., Saunderson, A., Allan, A., Anderson, F., Kaye, C., Liew, J., Medhora, J., Scott, T., Trumper, E., Botello, A., Polgarova, P., Stroud, K., Meaney, E., Jones, M., Ng, A., Agrawal, S., Pathan, N., White, D., Daubney, E., Elston, K., Parker, R., Reddy, A., Turner-Bone, I., Wilding, L., Harding, P., Jacob, R., Jones, C., Denmade, C., Croft, M., White, I., Griffin, D., Muchenje, N., Mupudzi, M., Partridge, R., Conyngham, J.A., Thomas, R., Wright, M., Corral, M.A., Bastion, V., Clarke, D., David, B., Kent, H., Lorusso, R., Lubimbi, G., Murdoch, S., Penacerrada, M., Thomas, A., Valentine, J., Vochin, A., Wulandari, R., Djeugam, B., Dawson, J., Garrioch, S., Tolson, M., Aldridge, J., de Almeida Martins, L.G., Carungcong, J., Beavis, S., Dale, K., Gascoyne, R., Hawes, J., Pritchard, K., Stevenson, L., Whileman, A., Cowley, A., Highgate, J., Crawley, R., Crew, A., Cunningham, M., Daniels, A., Harrison, L., Hope, S., Inweregbu, K., Jones, S., Lancaster, N., Matthews, J., Wray, G., Benham, L., Bradshaw, Z., Brown, J., Caswell, M., Melling, S., Preston, S., Slawson, N., Stoddard, E., Warden, S., Combes, E., Joefield, T., Monnery, S., Beech, V., Trotman, S., Hopkins, B., Scriven, J., Thrasyvoulou, L., Willis, H., Anderson, S., Birch, J., Hammerton, K., O'Leary, R., Abernathy, C., Foster, L., Gratrix, A., Martinson, V., Parkinson, P., Stones, E., Carbral-Ortega, L., Kapoor, R., Loader, D., Castle, K., Brandwood, C., Smith, L., Clark, R., Birchall, K., Kolakaluri, L., Baines, D., Sukumaran, A., Mapfunde, I., Meredith, M., Morris, L., Ryan, L., Clark, A., Sampson, J., Peters, C., Dent, M., Langley, M., Wei, S., Andrew, A., Chablani, M., Kirkby, A., Netherton, K., Bates, M., Dasgin, J., Gill, J., Nilsson, A., Apetri, E., Basikolo, C., Blackledge, B., Catlow, L., Charles, B., Doonan, R., Harris, J., Harvey, A., Horner, D., Knowles, K., Lomas, D., Lyons, C., Marsden, T., McLaughlan, D., McMorrow, L., Pendlebury, J., Perez, J., Poulaka, M., Proudfoot, N., Slaughter, M., Slevin, K., Thomas, V., Walker, D., Michael, A., Collis, M., Clark, M., Coulding, M., Jude, E., McCormick, J., Mercer, O., Potla, D., Rehman, H., Savill, H., Turner, V., Davey, M., Golden, D., Seaman, R., Hunt, J., Dearden, J., Dobson, E., Mulcahy, M., Munt, S., O'Connor, G., Philbin, J., Rishton, C., Tully, R., Winnard, S., Cagova, L., Fofano, A., Garner, L., Holcombe, H., Mepham, S., Mitchell, A.M., Mwaura, L., Zamikula, J., Bercades, G., Brealey, D., Hass, I., MacCallum, N., Martir, G., Raith, E., Reyes, A., Smyth, D., Taylor, A., Hughes, R.A., Thomas, H., Rees, A., Duskova, M., Phipps, J., Brooks, S., Edwards, M., Alexander, P., Allen, S., Bradley-Potts, J., Brantwood, C., Egan, J., Felton, T., Padden, G., Ward, L., Moss, S., Glasgow, S., Beesley, K., Board, S., Kubisz-Pudelko, A., Lewis, A., Perry, J., Pippard, L., Wood, D., Buckley, C., Brown, A., Gregory, J., O'Connell, S., Smith, T., Belagodu, Z., Fuller, B., Gherman, A., Olufuwa, O., Paramsothy, R., Stuart, C., Oakley, N., Kamundi, C., Tyl, D., Collins, K., Silva, P., Taylor, J., King, L., Coates, C., Crowley, M., Wakefield, P., Beadle, J., Johnson, L., Sargeant, J., Anderson, M., Jardine, C., Williams, D., Parris, V., Quaid, S., Watson, E., Melville, J., Naisbitt, J., Joseph, R., Lazo, M., Walton, O., Neal, A., Hill, M., Kannan, T., Wild, L., Allan, E., Darlington, K., Davies, F., Easton, J., Kumar, S., Lean, R., Menzies, D., Pugh, R., Qiu, X., Davies, L., Williams, H., Scanlon, J., Davies, G., Mackay, C., Lewis, J., Rees, S., Coetzee, S., Gales, A., Raj, M., Sell, C., Langton, H., Watters, M., Novis, C., Arbane, G., Bociek, A., Campos, S., Grau, N., Jones, T.O., Lim, R., Marotti, M., Whitton, C., Barron, A., Collins, C., Kaul, S., Passmore, H., Prendergast, C., Reed, A., Rogers, P., Shokkar, R., Woodruff, M., Middleton, H., Polgar, O., Nolan, C., Thwaites, V., Mahay, K., Sri-Chandana, C., Scherewode, J., Stephenson, L., Marsh, S., Bancroft, H., Bellamy, M., Carmody, M., Daglish, J., Moore, F., Rhodes, J., Sangombe, M., Kadiri, S., Ayers, A., Harrison, W., North, J., Cavazza, A., Cockrell, M., Corcoran, E., Depante, M., Finney, C., Jerome, E., McPhail, M., Nayak, M., Noble, H., O'Reilly, K., Pappa, E., Saha, R., Saha, S., Smith, J., Knighton, A., Gill, M., Paul, P., Ratnam, V., Shelton, S., Wynter, I., Baptista, D., Crowe, R., Fernandes, R., Herdman-Grant, R., Joseph, A., Loveridge, A., McKenley, I., Morino, E., Naranjo, A., Simms, R., Sollesta, K., Swain, A., Venkatesh, H., Khera, J., Fox, J., Barber, R., Hewitt, C., Hilldrith, A., Jackson-Lawrence, K., Shepardson, S., Wills, M., Butler, S., Tavares, S., Cunningham, A., Hindale, J., Arif, S., George, L., Twiss, S., Wright, D., Holland, M., Keenan, N., Lyons, M., Wassall, H., Marsh, C., Mahenthran, M., Carter, E., Kong, T., Adanini, O., Bhatia, N., Msiska, M., Mew, L., Mwaura, E., Williams, F., Wren, L., Sutherland, S.B., Battle, C., Brinkworth, E., Harford, R., Murphy, C., Newey, L., Rees, T., Arnold, S., Hardy, J., Houlden, H., Moncur, E., Tariq, A., Tucci, A., Convery, K., Fottrell-Gould, D., Hudig, L., Keshet-Price, J., Randell, G., Stammers, K., Abdelrazik, M., Bakthavatsalam, D., Elhassan, M., Ganesan, A., Haldeos, A., Moreno-Cuesta, J., Purohit, D., Vincent, R., Xavier, K., Rohit, K., Alasdair, F., Saleem, M., David, C., Jenkins, S., Lamond, Z., Wall, A., Reynolds, J., Campbell, H., Thompsom, M., Dodds, S., Duffy, S., Butcher, D., O'Sullivan, S., Butterworth-Cowin, N., Deacon, B., Hibbert, M., Pothecary, C., Tetla, D., Woodford, C., Durga, L., Kennard-Holden, G., de Gordoa, L.O., Peasgood, E., Phillips, C., Skinner, D., Gaylard, J., Mullan, D., Newman, J., Davies, E., Roche, L., Sathe, S., Brimfield, L., Daly, Z., Pogson, D., Rose, S., Collins, A., Khaliq, W., Gude, E.T., Allen, L., Beranova, E., Crisp, N., Deery, J., Hazelton, T., Knight, A., Price, C., Tilbey, S., Turki, S., Turney, S., Giles, J., Booth, S., Bell, G., English, K., Katary, A., Wilcox, L., Campbell, R., Clarke, N., Whiteside, J., Mascarenhas, M., Donaldson, A., Matheson, J., Barrett, F., O'Hara, M., O'Keefe, L., Bradley, C., Walker, R., Maynard, V., Patel, T., Smith, M., Kazi, A., Hartley, J., Dykes, J., Hijazi, M., Keith, S., Khan, M., Ryan-Smith, J., Springle, P., Truman, N., Saad, S., Coleman, D., Fine, C., Matt, R., Gay, B., Dalziel, J., Ali, S., Goodchild, D., Harling, R., Bhatterjee, R., Goddard, W., Davison, C., Duberly, S., Hargreaves, J., Bolton, R., Verlander, M., Blackman, H., Creagh-Brown, B., Donlon, S., Michalak-Glinska, N., Mtuwa, S., Pristopan, V., Salberg, A., Smith, E., Stone, S., Piercy, C., Verula, J., Burda, D., Montaser, R., Harden, L., Mayangao, I., Marriott, C., Bradley, P., Harris, C., Cooper, J., Finch, C., Liderth, S., Quinn, A., Waddington, N., Fidler, K., Tagliavini, E., Donnelly, K., Abel, L., Brett, M., Digby, B., Gemmell, L., Hornsby, J., MacGoey, P., O'Neil, P., Price, R., Rodden, N., Rooney, K., Sundaram, R., Thomson, N., Flanagan, R., Hughes, G., Latham, S., McKenna, E., Anderson, J., Hull, R., Rhead, K., Branney, D., Frankham, J., Pitts, S., White, N., Cristiano, D., Dormand, N., Farzad, Z., Gummadi, M., Liyanage, K., Patel, B.V., Salmi, S., Sloane, G., Varghese, M., Zborowski, A.C., Bean, S., Burt, K., Spivey, M., Eastgate-Jackson, C., Filipe, H., Martin, D., Maharajh, A., Garcia, S.M., De Neef, M., Lynch, C., Howe, G.S., Singh, J., Turner, K., Ellis, H., Stroud, N., Cherian, S., Cutler, S., Heron, A.E., Roynon-Reed, A., Williams, G., Richards, O., Cheema, Y., Ahmad, N., Barker, J., Bauchmuller, K., Bird, S., Cawthron, K., Harrington, K., Jackson, Y., Kibutu, F., Lenagh, B., Masuko, S., Raithatha, A., Wiles, M., Willson, J., Newell, H., Lye, A., Nwafor, L., Jarman, C., Rowland-Jones, S., Foote, D., Cole, J., Watson, J., Hesseldon, L., Macharia, I., Chetam, L., Ford, A., Housley, K., Milner, L., Hanratty, H., Trower, H., Phillips, P., Oxspring, S., Donne, B., Bevan, E., Martin, J., Trodd, D., Watson, G., Brown, C.W., Bunni, L., Jennings, C., Latif, M., Marshall, R., Subramanian, G., Bandla, N., Gellamucho, M., Davies, M., Trim, F., Eapen, B., Ahmed, C., Baines, B., Clamp, S., Colley, J., Haq, R., Hayes, A., Hulme, J., Joseph, S., Kumar, R., Maqsood, Z., Purewal, M., Chandler, B., Elliott, K., Mallinson, J., Turnbull, A., Dent, K., Horsley, E., Akhtar, M.N., Pearson, S., Potoczna, D., Spencer, S., Blakemore, H., Borislavova, B., Faulkner, B., Gendall, E., Goff, E., Hayes, K., Thomas, M., Worner, R., Smith, K., Stephens, D., Delgado, C.C., Dawson, D., Ding, L., Durrant, G., Ezeobu, O., Farnell-Ward, S., Harrison, A., Kanu, R., Leaver, S., Maccacari, E., Manna, S., Saluzzio, R.P., Queiroz, J., Samakomva, T., Sicat, C., Texeira, J., Da Gloria, E.F., Lisboa, A., Rawlins, J., Mathew, J., Kinch, A., Hurt, W.J., Shah, N., Clark, V., Thanasi, M., Yun, N., Patel, K., Crickmore, V., Debreceni, G., Wilkins, J., Nicol, L., Burn, I., Hambrook, G., Manso, K., Penn, R., Shanmugasundaram, P., Tebbutt, J., Thornton, D., Rostron, A., Roy, A., Woods, L., Cornell, S., Wakinshaw, F., Rogerson, K., Jarmain, J., Anderson, P., Archer, K., Austin, K., Davis, C., Durie, A., Kelsall, O., Thrush, J., Vigurs, C., Wood, H.L., Tranter, H., Cowley, N., McAlindon, M., Digby, S., Low, E., Morgan, A., Cother, N., Rankin, T., Clayton, S., McCurdy, A., Allibone, S., Mary-Genetu, R., Patel, A., Mac, A., Murphy, A., Mahjoob, P., Nazari, R., Worsley, L., Fagan, A., Mohamed Ali, I.A., Beaumont, K., Blunt, M., Coton, Z., Curgenven, H., Elsaadany, M., Fernandes, K., Ally, S.M., Rangarajan, H., Sarathy, V., Selvanayagam, S., Vedage, D., White, M., Fernandez-Roman, J., Hamilton, D.O., Johnson, E., Johnston, B., Martinez, M.L., Mulla, S., Shaw, D., Waite, AAC, Waugh, V., Welters, I.D., Williams, K., Bemand, T., Black, E., Rosa, A.D., Howle, R., Jhanji, S., Baikady, R.R., Tatham, K.C., Thomas, B., Halkes, M., Mercer, P., Thornton, L., West, J., Baird, T., Ruddy, J., Reece-Anthony, R., Birt, M., Cowton, A., Kay, A., Kent, M., Potts, K., Wilkinson, A., Naylor, S., Brown, E., Purvis, S., Davies, R., Duffin, D., Hill, H., Player, B., Thomas, E., Beith, C.M., Black, K., Clements, S., Morrison, A., Strachan, D., Clarkson, M., D'Sylva, S., Norman, K., Coventry, T., Fowler, S., McGregor, A., Brady, A., Chan, R., McIvor, S., Prady, H., Whittle, H., Mathew, B., Clapham, M., Harper, R., Poultney, U., Rice, P., Mutch, R., Baird, Y., Butler, A., Chadbourn, I., Folkes, L., Fox, H., Gardner, A., Gomez, R., Hobden, G., King, K., Margarson, M., Martindale, T., Meadows, E., Raynard, D., Thirlwall, Y., Helm, D., Margalef, J., Greer, S., Shuker, K., Smuts, S., Duffield, J., Smith, O., Mallon, L., Claire, W., Birkinshaw, I., Carter, J., Howard, K., Ingham, J., Joy, R., Pearson, H., Roche, S., Scott, Z., Knights, E., Price, A., Thorpe, C., Abraheem, A., Bamford, P., Cawley, K., Dunmore, C., Faulkner, M., Girach, R., Jeffrey, H., Jones, R., London, E., Nagra, I., Nasir, F., Sainsbury, H., Smedley, C., Khade, R., Sundar, A., Tsinaslanidis, G., Behan, T., Burnett, C., Hatton, J., Heeney, E., Mitra, A., Newton, M., Pollard, R., Stead, R., Bough, L., Goodsell, J., Tutton, R., Williams, P., Williams, S., Winter-Goodwin, B., Auld, F., Donnachie, J., Edmond, I., Prentice, L., Runciman, N., Salutous, D., Symon, L., Todd, A., Turner, P., Short, A., Sweeney, L., Murdoch, E., Senaratne, D., Burns, K., Higham, A., Anderson, T., Hawcutt, D., O'Malley, L., Rad, L., Rogers, N., Saunderson, P., Allison, K.S., Afolabi, D., Whitbread, J., Jones, D., Dore, R., Lankester, L., Nikitas, N., Wells, C., Stowe, B., Spencer, K., Cathcart, S., Duffy, K., Puxty, A., Puxty, K., Turner, L., Ireland, J., Semple, G., Barry, P., Hilltout, P., Evitts, J., Tyler, A., Waldron, J., Irvine, V., Shelley, B., Akinkugbe, O., Bamford, A., Beech, E., Belfield, H., Bell, M., Davies, C., Jones, GAL, McHugh, T., Meghari, H., O'Neill, L., Peters, M.J., Ray, S., Tomas, A.L., Gorman, C., Gupta, A., Timlick, E., Brady, R., Bonner, S., Hugill, K., Jones, J., Liggett, S., Bashyal, A., Davidson, N., Hutton, P., McKechnie, S., Wilson, J., Flint, N., Rekha, P., Hales, D., Cruz, C., Gopal, S., Harris, N., Lake, V., Metherell, S., Radford, E., Clement, I., Hays, C., Hudson, A., Webster, A., Stephenson, E., McCormack, L., Slater, V., Nixon, R., Hanson, H., Fearby, M., Kelly, S., Bridgett, V., Robinson, P., Almaden-Boyle, C., Austin, P., Cabrelli, L., Casey, M., Chapman, S., Whyte, C., Brayne, A., Fisher, E., Jackson, P., Kaye, D., Love, N., Parkin, J., Tuckey, V., van Koutrik, L., Carter, S., Andrew, B., Findlay, L., Adams, K., Bruce, M., Connolly, K., Duncan, T., T-Michael, H., Lindergard, G., Hey, S., Fox, C., Alfonso, J., Durrans, L.J., Guerin, J., Hruska, M., Eltayeb, A., Lamb, T., Hodgkiss, T., Cooper, L., Rothwell, J., Dennis, C., Srikaran, S., Sukha, A., Davies, K., O'Brien, L., Omar, Z., Perkins, E., Lewis, T., Sutherland, I., Brooke, H., Buckley, S., Suarez, J.C., Charlesworth, R., Hansson, K., Norris, J., Poole, A., Sandhu, R., Sloan, B., Smithson, E., Thirumaran, M., Wagstaff, V., Metcalfe, A., Camsooksai, J., Humphrey, C., Wadams, B., DeAth, Y., Adams, C., Agasou, A., Arden, T., Bowes, A., Boyle, P., Beekes, M., Button, H., Capps, N., Carnahan, M., Carter, A., Childs, D., Donaldson, D., Hard, K., Hurford, F., Hussain, Y., Javaid, A., Jose, S., Leigh, M., Martin, T., Millward, H., Motherwell, N., Rikunenko, R., Stickley, J., Summers, J., Ting, L., Tivenan, H., Tonks, L., Wilcox, R., Bokhari, M., Lucas, R., McCormick, W., Ritzema, J., Sanderson, A., Wild, H., Baxter, N., Henderson, S., Kennedy-Hay, S., Rooney, L., Sim, M., McCreath, G., Brunton, M., Caterson, J., Coles, H., Frise, M., Rai, S.G., Keating, L., Tilney, E., Bartley, S., Bhuie, P., Downes, C., Holding, K., Riches, K., Hilton, M., Hayman, M., Subramanian, D., Daniel, P., Zitter, L., Benyon, S., Marriott, S., Park, L., Keenan, S., Gordon, E., Quinn, H., Baines, K., Andrew, G., Barclay, L., Callaghan, M., Clark, S., Hope, D., Marshall, L., McCulloch, C., Briton, K., Singleton, J., Birch, S., Simpson, K., Craig, J., Demetriou, C., Eckbad, C., Hierons, S., Howie, L., Mitchard, S., Ramos, L., Serrano-Ruiz, A., White, K., Kelly, F., Amin, V., Anastasescu, E., Anumakonda, V., Karthik, K., Kausar, R., Reid, K., Imeson-Wood, J., Bellini, A., Bryant, J., Pickard, A., Roe, N., Sowter, J., Howlett, A., Criste, K., Cusack, R., Golder, K., Golding, H., Jones, O., Leggett, S., Male, M., Marani, M., Prager, K., Williams, T., Roberts, B., Salmon, K., Gondo, P., Kayani, A., Masunda, B., Ahmed, A., Morris, A., Jakkula, S., Long, K., Whiteley, S., Wilby, E., Ogg, B., Moultrie, S., Bewley, J., Garland, Z., Grimmer, L., Gumbrill, B., Sweet, K., Webster, D., Efford, G., Bennett, S., Goodwin, E., Jackson, M., Kent, A., Tibke, C., Woodyatt, W., Zaki, A., Daniel, A., Finn, J., Bremmer, P., Houston, G., O'Brien, P., Bell, D., Boyle, R., Douglas, K., Glass, L., Lee, E., Lennon, L., Rattray, A., Charnock, R., McFarland, D., Cosgrove, D., Attwood, B., Parsons, P., Carmody, S., Oblak, M., Popescu, M., Thankachen, M., Baruah, R., Morris, S., Ferguson, S., Shepherd, A., Altabaibeh, A., Alvaro, A., Gilbert, K., Ma, L., Mostoles, L., Parmar, C., Jetha, C., Booker, L., Pratley, A., Cosier, T., Millen, G., Schumacher, N., Weston, H., Rand, J., Alex, B., Bach, B., Barclay, W.S., Bogaert, D., Chand, M., Cooke, G.S., Docherty, A.B., Dunning, J., da Silva Filipe, A., Fletcher, T., Green, C.A., Harrison, E.M., Hiscox, J.A., Ijaz, S., Khoo, S., Lim, W.S., Mentzer, A.J., Merson, L., Noursadeghi, M., Moore, S.C., Palmarini, M., Paxton, W.A., Pollakis, G., Price, N., Rambaut, A., Robertson, D.L., Sancho-Shimizu, V., Scott, J.T., de Silva, T., Sigfrid, L., Solomon, T., Sriskandan, S., Stuart, D., Tedder, R.S., Thomson, E.C., Roger Thompson, A.A., Thwaites, R.S., Turtle, LCW, Gupta, R.K., Palmieri, C., Swann, O.V., Zambon, M., Dumas, M.E., Griffin, J.L., Takats, Z., Chechi, K., Andrikopoulos, P., Osagie, A., Olanipekun, M., Liggi, S., Lewis, M.R., Correia, GDS, Sands, C.J., Takis, P., Maslen, L., Greenhalf, W., Shaw, V., McDonald, S.E., Ahmed, K.A., Armstrong, J.A., Ashworth, M., Asiimwe, I.G., Bakshi, S., Barlow, S.L., Booth, L., Brennan, B., Bullock, K., Catterall, BWA, Clark, J.J., Clarke, E.A., Cox, H., Dincarslan, O., Dunn, C., Dyer, P., Elliott, A., Evans, A., Finch, L., Fisher, LWS, Foster, T., Garcia-Dorival, I., Gunning, P., Hartley, C., Jensen, R.L., Jones, C.B., Jones, T.R., Khandaker, S., Kiy, R.T., Koukorava, C., Lake, A., Lant, S., Latawiec, D., Lavelle-Langham, L., Lefteri, D., Lett, L., Livoti, L.A., Mancini, M., McDonald, S., McEvoy, L., McLauchlan, J., Metelmann, S., Miah, N.S., Middleton, J., Mitchell, J., Murphy, E.G., Penrice-Randal, R., Pilgrim, J., Prince, T., Reynolds, W., Ridley, P.M., Sales, D., Shaw, V.E., Shears, R.K., Small, B., Subramaniam, K.S., Szemiel, A., Taggart, A., Tanianis-Hughes, J., Trochu, E., van Tonder, L., Wilcock, E., Zhang, J.E., Flaherty, L., Maziere, N., Cass, E., Carracedo, A.D., Carlucci, N., Holmes, A., Massey, H., Murphy, L., Wrobel, N., McCafferty, S., Morrice, K., MacLean, A., Armstrong, R., Boz, C., Coutts, A., Cullum, L., Day, N., Donnelly, L., Duncan, E., Fawkes, A., Finernan, P., Gilchrist, T., Golightly, A., Hafezi, K., Law, D., Law, R., Law, S., Macgillivray, L., Maclean, A., Mal, H., Mcmaster, E., Meikle, J., Oosthuyzen, W., Paterson, T., Stenhouse, A., Swets, M., Szoor-McElhinney, H., Taneski, F., Wackett, T., Ward, M., Weaver, J., Coyle, J., Gallagher, B., Lidstone-Scott, R., Hamilton, D., Schon, K., Furlong, A., Biggs, H., Griffiths, F., Andrews, E., Brickell, K., Smyth, M., Carson, G., Hardwick, H., Donohue, C., Neale, Benjamin M. [0000-0003-1513-6077], Apollo - University of Cambridge Repository, Stem Cell Aging Leukemia and Lymphoma (SALL), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Life Course Epidemiology (LCE), Groningen Research Institute for Asthma and COPD (GRIAC), Guided Treatment in Optimal Selected Cancer Patients (GUTS), AII - Infectious diseases, Amsterdam Neuroscience - Neuroinfection & -inflammation, Neurology, Infectious diseases, Center of Experimental and Molecular Medicine, APH - Aging & Later Life, APH - Global Health, APH - Quality of Care, Amsterdam institute for Infection and Immunity, APH - Health Behaviors & Chronic Diseases, Global Health, APH - Methodology, Graduate School, ACS - Heart failure & arrhythmias, Anesthesiology, ACS - Diabetes & metabolism, APH - Digital Health, APH - Personalized Medicine, ACS - Microcirculation, Niemi, M. E. K., Liao, R. G., Neale, B. M., Pathak, G. A., Andrews, S. J., Schulte, E. C., Karim, M. A., Wendt, F. R., Kim, H. -N., Uddin, M. J., Smith, G. D., Willer, C. J., Buxbaum, J. D., Martin, A. R., Balaconis, M. K., Sankaran, V. G., Brent Richards, J., Eric Kerchberger, V., Kenneth Baillie, J., Dutta, A. K., Uddin, M. M., Perez-Tur, J., Verdugo, R. A., Zarate, R., Medina-Gomez, C., Gomez-Cabrero, D., Cadilla, C. L., Boua, P. R., Fave, M. -J., Lemacon, A., Szentpeteri, J. L., Ahmad, H. F., Kornilov, S. A., Prokic, I., Pearson, N. M., Shelton, J. F., Shastri, A. J., Weldon, C. H., Brouwer, M. C., Vlaar, A. P. J., Joost Wiersinga, W., Algera, A. G., Bogaard, H. J., Bonta, P. I., Grobusch, M. P., Hermans, S. M., Hovius, J. W., de Jong, M. D., Nossent, E. J., Prins, J. M., Schultz, M. J., Stijnis, C. S., Minnaar, R. P., van Uffelen, K. W. J., Wolterman, R. A., Ball, C. A., Mccurdy, S., Hong, E. L., Baltzell, A. H., Goffard, J. -C., Peree, H., Leonard, P., Giot, J. -B., Sauvage, A. -S., Wery, M., Morrison, D. R., Chasse, M., Kaufmann, D. E., Mark Lathrop, G., Davis, L. K., Cox, N. J., Below, J. E., Sealock, J. M., Faucon, A. B., Shuey, M. M., Polikowsky, H. G., Petty, L. E., Shaw, D. M., Chen, H. -H., Ludwig, K. U., Schroder, J., Nothen, M. M., Jensen, B. -E. O., Altmuller, J., Berger, M. M., Gogele, M., Gignoux, C. R., Wicks, S. J., Barnes, K. C., Goldstein, D. B., Reilly, M. P., Gharavi, A. G., O'Byrne, S. M., So, Y. S., Park, S. -K., Kim, H. -L., Kang, C. K., Lee, H. -J., Song, K. -H., Yoon, K. J., Paik, N. -J., Joo, E. -J., Park, W. B., Park, J. S., Park, K. U., Ham, S. Y., Kim, E. S., Kim, H. B., Caceres, M., Lenz, T. L., Julia, A., Holter, J. C., Fernandez, J., Sander, L. E., Banales, J. M., Romero-Gomez, M., Hov, J. R., Karlsen, T. H., Wacker, E. M., Elabd, H., Ruhlemann, M. C., Vadla, M. S., Lenning, O. B., Ozer, O., Kassens, J., Figuera Basso, M. E., Ortiz, A. B., Chercoles, A. G., Holten, A. R., Kildal, A. B., Gluck, A., Nolla, A. C., Dyrhol-Riise, A. M., Spinner, C. D., Hoff, D. A. L., Jimenez, D., Pestana, D., Helbig, E. T., Paraboschi, E. M., Sanchez, F. G., Hernandez, I., Galvan-Femenia, I., Badia, J. R., Muller, K. E., Gaede, K. I., Lippert, L. J., Tellez, L., Gutierrez-Stampa, M. A., Vehreschild, M. J. G. T., Marquie, M., Seilmaier, M. J., Rodriguez-Gandia, M., Ayo, N. I., Martinez, N., Cornely, O. A., Rodrigues, P. M., Espana, P. P., Garcia-Fernandez, A. -E., Fracanzani, A. L., Muniz-Diaz, E., Calderon, E. J., Solligard, E., Medrano, F. J., Muller, F., Afset, J. E., Damas, J. K., Ferrusquia-Acosta, J., Quero, J. H., Guerrero, J. M., Bettini, L. R., Gustad, L. T., Valsecchi, M. G., D'Angio, M., Gallego-Duran, R., Cejudo, T. G., Grimsrud, M. M., Gudbjartsson, D. F., Moore, K. H. S., Alarcon-Riquelme, M. E., Martinez-Bueno, M., Rello, S. R., Lall, K., Bochud, P. -Y., Nussle, S. G., Meyer zu Bentrup, F., Merlet Viollet, R., Guery, B., Hugli, O., Gonseth Nussle, S., Estoppey Younes, S., Rochat Negro, T., Mercader, J. M., Castano-Vinyals, G., Dobano, C., Mondelli, M. U., Mazzei, M. A., Caldarelli, G. P., Monforte, A. D., Scotton, P. G., Monica, M. D., Mandala, M., Coviello, D. A., La Rovere, M. T., Segala, F. V., Mencarelli, M. A., Pinto, A. M., Carriero, M. L., Ann Belli, M., Antoni, M. D., Miraglia, F. G., Parisi, S. G., Squeo, G. M., Botta, G., Hunt, K. A., Trembath, R. C., Martin, H. C., Griffiths, C. J., Curtis, C. J., Huang, Q. Q., Lee, S. H., Macarthur, D., Maclaughlin, B., Smith, A. V., Boughton, A. P., Li, K. W., Lefaive, J., Jannes, C. E., Krieger, J. E., Pereira, A. C., Lima, I. R., Tada, M. T., Mccarthy, M., Lee, J. E., Lee, H. S., Jang, H. Y., Kim, Y. -S., Kwon, K. T., Kim, S. -W., Kim, J. Y., Jang, Y. R., Kim, H., Lee, J. Y., Choe, K. -W., Kang, Y. M., Jee, S. H., Jung, K. J., Schroth, G. P., Desouza, F., Cirulli, E. T., Schiabor Barrett, K. M., Washington, N. L., Lu, J. T., Ramirez, J. M., Grzymski, J. J., Minano, J. I. E., Aguirre, L. A., Lopez-Collazo, E., Lozano-Rodriguez, R., Avendano-Ortiz, J., Arcos, V. T., Montalban-Hernandez, K. M., Quiroga, J. V., Martin-Quiros, A., Nakada, T. -A., Vonk, J. M., Ori, A. P. S., Hernandez Cordero, A. I., Sin, D. D., Bosse, Y., Feng, Y. -C. A., Weiss, S. T., Karlson, E. W., Smoller, J. W., Murphy, S. N., Meigs, J. B., Woolley, A. E., Green, R. C., Perez, E. F., Zollner, S., Sloofman, L. G., Sebra, R. P., Collins, B. L., Sealfon, S. C., Jordan, D. M., Thompson, R. C., Belbin, G. M., Underwood, S. J., Hiester, L. L., Charney, A. W., Beckmann, N. D., Schadt, E. E., Abul-Husn, N. S., Cho, J. H., Kenny, E. E., Loos, R. J. F., Nadkarni, G. N., Huckins, L. M., Ferreira, M. A. R., Abecasis, G. R., Leader, J. B., Cantor, M. N., Justice, A. E., Carey, D. J., Josyula, N. S., Kosmicki, J. A., Horowitz, J. E., Gass, M. C., Hottenga, J. J., de Geus, E. J. C., Nivard, M. G., Ritchie, M. D., Verma, S. S., Vari, M. S., Rahier, J. -F., Bulik, C. M., Landen, M., Ferrero, G. B., Fundin, B., Ismail, S. I., Badji, R. M., Hultstrom, M., Geschwind, D. H., Butte, M. J., Chang, T. S., Caulfield, M. J., Scott, R. H., Odhams, C. A., Karczewski, K. J., Wilson, D. J., Spencer, C. A., Crook, D. W., Wyllie, D. H., O'Connell, A. M., Atkinson, E. G., Walters, R. K., Palmer, D. S., Goldstein, J. I., Kyle Satterstrom, F., Earle, S. G., Lin, S. -K., Rudkin, J. K., Zhao, J. H., Butterworth, A. S., Sun, Y. V., Huffman, J. E., O'Donnell, C. J., Michael Gaziano, J., Ho, Y. -L., Glessner, J. R., Mcguigan, P. J., Moore, L. S. P., Vizcaychipi, M. P., Page, V. J., Aldera, E. L., Cutino-Moguel, M. -T., Durand, I., Hawcutt, D. B., Macmahon, M., Macnaughton, E., Mccullough, K., Mcewen, R., O'Shea, M. K., Pooni, J. S., Wooton, D. G., Bretherick, A. D., Fourman, M. H., Meynert, A. M., Ponting, C. P., Porteous, D. J., Russell, C. D., Wilson, J. F., Drake, T. M., Fairfield, C. J., Knight, S. R., Mclean, K. A., Shaw, C. A., Ho, A. Y. W., Horby, P. W., Mcauley, D., Openshaw, P. J. M., Semple, M. G., Mcgowan, J., Mcguinness, H., Mcneela, F., Bayo, L. -A., Arias, S. S., Conyngham, J. -A., Corral, M. A., de Almeida Martins, L. G., Mclaughlan, D., Mcmorrow, L., Mccormick, J., Mitchell, A. M., Maccallum, N., Hughes, R. A., Jones, T. O., Mcphail, M., Mckenley, I., Sutherland, S. -B., de Gordoa, L. O. -R., Gude, E. T., Macgoey, P., Mckenna, E., Patel, B. V., Zborowski, A. C., Garcia, S. M., Howe, G. S., Heron, A. E., Mills, G. H., Brown, C. W., Akhtar, M. N., Delgado, C. C., Saluzzio, R. P., Da Gloria, E. F., Hurt, W. J., Wood, H. -L., Mcalindon, M., Mccurdy, A., Ali, I. A. M., Ally, S. M., Hamilton, D. O., Lopez Martinez, M., Waite, A. A. C., Welters, I. D., Rosa, A. D., Baikady, R. R., Tatham, K. C., Beith, C. M., Mcgregor, A., Mcivor, S., Allison, K. S., Jones, G. A. L., Mchugh, T., Peters, M. J., Tomas, A. L., Mckechnie, S., Mccormack, L., Michael, H. T., Durrans, L. J., Suarez, J. C., Death, Y., Mccormick, W., Mccreath, G., Rai, S. G., Mcculloch, C., Mcfarland, D., Barclay, W. S., Cooke, G. S., Docherty, A. B., Green, C. A., Harrison, E. M., Hiscox, J. A., Lim, W. S., Mentzer, A. J., Paxton, W. A., Robertson, D. L., Scott, J. T., Tedder, R. S., Thomson, E. C., Thwaites, R. S., Gupta, R. K., Swann, O. V., Dumas, M. -E., Griffin, J. L., Lewis, M. R., dos Santos Correia, G., Sands, C. J., Mcdonald, S. E., Ahmed, K. A., Armstrong, J. A., Asiimwe, I. G., Barlow, S. L., Catterall, B. W. A., Clark, J. J., Clarke, E. A., Fisher, L. W. S., Jensen, R. L., Jones, C. B., Jones, T. R., Kiy, R. T., Livoti, L. A., Mcdonald, S., Mcevoy, L., Mclauchlan, J., Miah, N. S., Moore, S. C., Murphy, E. G., Matthew Ridley, P., Shaw, V. E., Shears, R. K., Subramaniam, K. S., Eunice Zhang, J., Carracedo, A. D., Mccafferty, S., Turtle, L. C. W., Data Science Genetic Epidemiology Lab, Institute for Molecular Medicine Finland, HUS Helsinki and Uusimaa Hospital District, University of Helsinki, Research Programs Unit, Doctoral Programme in Population Health, Centre of Excellence in Complex Disease Genetics, Aarno Palotie / Principal Investigator, Genomics of Neurological and Neuropsychiatric Disorders, and University of Zurich
Subjects: Male, 45/43, Autoimmunity, Autoimmunity/genetics, Body Mass Index, COVID-19/genetics, COVID-19/virology, Critical Illness, Female, Genetic Loci/genetics, Genetic Predisposition to Disease, Genome-Wide Association Study, Geographic Mapping, Hospitalization, Host-Pathogen Interactions/genetics, Humans, Inflammation/complications, Information Dissemination, Multifactorial Inheritance, Racial Groups/genetics, SARS-CoV-2/pathogenicity, Smoking, environmental risk factors, Q1, 631/208, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Genetics, Genome-wide association studies, SARS-CoV-2, Viral infection, GWAS, Aetiology, Lung, QC, 0303 health sciences, HERITABILITY, 3. Good health, covid-19, Science & Technology - Other Topics, Identification (biology), Infection, Human, 631/208/205/2138, Settore BIO/11 - Biologia Molecolare, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Clinical Research, Biodefense, Genetics, GENOME-WIDE ASSOCIATION, Medisinske Fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710::Medisinsk genetikk: 714 [VDP], METAANALYSIS, 1000 Multidisciplinary, [SDV.GEN]Life Sciences [q-bio]/Genetics, Science & Technology, Prevention, Racial Groups, Pneumonia, genetic architecture, Human genetics, Genetic Loci, genetic factors, 570 Life sciences, biology, 030217 neurology & neurosurgery, Medizin, Infektionsmedicin, Genome-wide association studies, Settore BIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICA, Pandemic, 2.1 Biological and endogenous factors, pandemi, Multidisciplinary, article, Public Health, Global Health, Social Medicine and Epidemiology, Racial Group, 10124 Institute of Molecular Life Sciences, Host-Pathogen Interaction, Multidisciplinary Sciences, Infectious Diseases, Host-Pathogen Interactions, Critical Illne, COVID-19, GWAS, genetic factors, environmental risk factors, therapy, Infectious Medicine, Coronavirus disease 2019 (COVID-19), SUSCEPTIBILITY LOCI, General Science & Technology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Computational biology, Biology, Vaccine Related, 692/699/255/2514, Environmental risk, Mendelian randomization, COVID-19 Host Genetics Initiative, QH426, 631/326/596/4130, 030304 developmental biology, Inflammation, therapy, SARS-CoV-2, Human Genome, COVID-19, Genetic architecture, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Emerging Infectious Diseases, Good Health and Well Being, Viral infection, 3111 Biomedicine
Abstract: Niemi, Mari E. K. et al. 39 páginas, figuras y tablas. Contiene material suplementario., The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases3-7. They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease.
Published: 2021
Full Text: View/download PDF

Catalog

Books, media, physical & digital resources

See catalog results

Searchworks

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources

Refine your results

13 results on '"Sun, Y.V."'

1. The power of genetic diversity in genome-wide association studies of lipids

2. Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism

3. Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events A GENIUS-CHD Study of Individual Participant Data

4. Subsequent Event Risk in Individuals With Established Coronary Heart Disease

5. Erratum to: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

6. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

7. Pleiotropic genes for metabolic syndrome and inflammation

8. A genome-wide association study of depressive symptoms

9. Association Between Chromosome 9p21 Variants and the Ankle-Brachial Index Identified by a Meta-Analysis of 21 Genome-Wide Association Studies

10. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

11. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

12. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

13. Mapping the human genetic architecture of COVID-19

Catalog

Searchworks

Select search scope, currently: Articles Catalog books, media & more in Jio Institute collections Articles journal articles & other e-resources

Search

Search Constraints

Refine your results

Search Limiters

Topic

Publication Year Range

Language

Publication Type

Database

13 results on '"Sun, Y.V."'

Search Results

Catalog

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources