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In today's society, sustainability has become a key theme, and utilizing renewable energy is part of sustainability. Under the high proportion of renewable energy access, the conventional grid is gradually shifting to an active and distributed structure, which makes the existing cost apportionment method of transmission and distribution projects unable to match the actual situation. Reasonable apportionment of the costs of different voltage levels is the basis for the evaluation of transmission and distribution projects and is important for the formulation of transmission and distribution tariffs, which in turn have a significant impact on the development of renewable energy. To this end, this paper takes China's power system as the research object and firstly analyzes the impact of the activization of the grid on the cost apportionment of transmission and distribution projects and then the inadequacy of the existing cost apportionment, which only considers a single factor and part of the cost which should be apportioned downward is still borne by this voltage level, and then combines the activation and the inherent characteristics of the power grid to extract the multiple factors to be considered for cost apportionment, and at the same time takes into account the reverse direction of the power trend, and divides the cost apportionment into two scenarios. The cost sharing model of transmission and distribution projects based on multiple apportionment factors is established. Finally, the feasibility and applicability of the model are verified by the examples of linear and reticulated grids, and the cost sharing results obtained by this method and the traditional method are compared. Using this method for the cost sharing of transmission and distribution projects, lower voltage levels will share more costs, and higher voltage levels will share fewer costs. The results show that the inclusion of the factors affecting cost sharing in the case of an active grid is more in line with the development trend of the new power system; the cost apportionment method based on multiple sharing factors makes the results fairer; and the inclusion of the power trend conduction relationship in the sharing process reflects the essential attributes of the grid. This is conducive to improving the operational efficiency of the power grid and promoting the long-term sustainability of the power system. [ABSTRACT FROM AUTHOR]

Sonodynamic Therapy (SDT) is a non-invasive means of eaneer treatment using focused ultrasound. The synergistic strategy based on SDT for liver cancer has high research significance and clinical translational value. This paper summarized the therapeutic mechanism and common acoustic sensitivities of SDT, analyzed the reasons why it is difficult to satisfy the current treatment of liver cancer tumors based on single mode acoustic dynamic therapy, and focused on the research progress of acoustic dynamic therapy, chemotherapy, photodynamic therapy, photothermal therapy and other dual synergistic treatment modes, as well as multi-mode synergistic therapy based on acoustic dynamic therapy. The aim is to provide reference and guidance for the future SDT collaborative mode treatment of liver cancer and other types of cancer. At the same time, it points out that SDT collaborative therapy still faces problems in the research process, such as the insignificant effect of single therapy and the few studies on multi-modal combined therapy. Finally, it puts forward the development prospect of developing new acoustic sensitizing agents, exploring the mechanism of combined therapy and realizing real-time diagnosis and treatment. [ABSTRACT FROM AUTHOR]

In this letter, a novel method is proposed to suppress the terrain fluctuation clutter based on adaptive broadening processing. In the proposed algorithm, the flat interference phase is first compensated according to the priori radar system parameters. Then, according to the space-time trajectory distribution of clutter edge, the level of clutter Doppler spread in virtue of crab effect is estimated by a cost function related to the clutter eigenvector matrix. Finally, after calculating the clutter suppression weight vector according to the broadened clutter subspace, the non-stationary ground clutter can be robustly rejected. The validity of the proposed method is verified by both the simulated and real-measured multichannel radar data. [ABSTRACT FROM AUTHOR]

Purpose: With all-pervasive presence of extremely low-frequency electromagnetic field (ELF-EMF) in modern life, ELF-EMF has been regarded as an essential factor which may induce changes in many organisms. The objective of the present study was to investigate the physiological responses of Caenorhabditis elegans (C. elegans) to 50 Hz, 3 mT ELF-EMF exposure. Materials and methods: Worms were exposed to ELF-EMF from the egg stage until reaching the fourth larva (L4) stage. After exposure, expressions of the tricarboxylic acid (TCA) cycle enzymes were examined by qRT-PCR and western blot analysis. Two lipid metabolites were detected by GC-MS. Reactive oxygen species (ROS) level was detected by dichlorofluorescein staining and worm antioxidant system was investigated by enzymatic activity analysis, including detection of the superoxide dismutase and catalase (CAT) activity and the total antioxidant capacity (T-AOC). Results: The TCA cycle enzyme, fumarase was found with decreased expression under ELF-EMF exposure. And arachidonic acid (ArA) and prostaglandin E2(PGE2) showed elevated concentrations, with increased expression of prostaglandin E2 synthase (PGES-2) in ELF-EMF exposed worms. Significant elevation of ROS level was identified accompanied with the significant depression of T-AOC in response to ELF-EMF. Conclusions: Our results suggested that exposure to 50 Hz, 3 mT ELF-EMF in C. elegans can elicit disruptions of the TCA cycle metabolism and PGE2 formation, coupling ELF-EMF-induced oxidative stress responses. Our study probably will attract increasing attentions to the controllable application of ELF-EMF associated with health and disease. [ABSTRACT FROM AUTHOR]

Purpose: With all-pervasive presence of extremely low-frequency electromagnetic field (ELF-EMF) in modern life, ELF-EMF has been regarded as an essential factor which may induce changes in many organisms. The objective of the present study was to investigate the physiological responses of Caenorhabditis elegans ( C. elegans ) to 50 Hz, 3 mT ELF-EMF exposure. Materials and methods: Worms were exposed to ELF-EMF from the egg stage until reaching the fourth larva (L4) stage. After exposure, expressions of the tricarboxylic acid (TCA) cycle enzymes were examined by qRT-PCR and western blot analysis. Two lipid metabolites were detected by GC-MS. Reactive oxygen species (ROS) level was detected by dichlorofluorescein staining and worm antioxidant system was investigated by enzymatic activity analysis, including detection of the superoxide dismutase and catalase (CAT) activity and the total antioxidant capacity (T-AOC). Results: The TCA cycle enzyme, fumarase was found with decreased expression under ELF-EMF exposure. And arachidonic acid (ArA) and prostaglandin E 2 (PGE 2 ) showed elevated concentrations, with increased expression of prostaglandin E 2 synthase (PGES-2) in ELF-EMF exposed worms. Significant elevation of ROS level was identified accompanied with the significant depression of T-AOC in response to ELF-EMF. Conclusions: Our results suggested that exposure to 50 Hz, 3 mT ELF-EMF in C. elegans can elicit disruptions of the TCA cycle metabolism and PGE 2 formation, coupling ELF-EMF-induced oxidative stress responses. Our study probably will attract increasing attentions to the controllable application of ELF-EMF associated with health and disease.