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4. Dialil n-Sulfida Organik Menurunkan Kadar Lipid Plasma Darah dan Hati Itik Cihateup Fase Grower

Author

Mushawwir, Andi, Suwarno, Nono, and Permana, Ronnie

Abstract

Dialil n-Sulfida organic sangat berpotensial sebagai imbuhan pakan dalam mencegah lipogenic pada unggas. Penelitian ini bertujuan untuk mengkaji potensi dialil n-sulfida dalam menghambat biosinsisi lipid pada itik cihateup. Dua ratus itik cihateup berumur 12 minggu telah digunakan dalam penelitian ini. Sampel itik cihateup dibagi ke dalam 4 kelompok perlakuan, masing-masing D0, tanpa Dialil n-Sulfida (Dn-S); D1, 50 µL/sampel; D2, 100 µL/sampel dan D3, 150 µL/sampel. Pemberian dilakukan dengan cara oral selama dua bulan percobaan. Dn-S diisolasi dengan teknik distilasi bertingkat. Berdasarkan hasil penelitian menunjukkan pemberian dialil n-sulfida organik 150 µL/ekor/hari efektif menurunkan dan memperbaiki kondisi lipid plasma dan hati. Disimpulkan bahwa bahwa Dialil n-Sulfida (Dn-S), mampu menurunkan aktivitas lipogenesis dengan ditandai menurunnnya lipid plasma darah dan hati (khususnya TAG), serta meningkatnya kadar NEFA yang beredar dalam sistem sirkulasi. Dn-S juga mampu meningkatkan aktivitas transport lipid yaitu HDL, sehingga menurunkan kolesterol dalam system sirkulasi tapi meningkatkan depositnya di dalam jaringan hati.Kata kunci: Dialil n-Sulfida, itik, lipidOrganic Dialil n-Sulfide Decrease Lipid in Blood Plasm and Liver of Cihateup Grower DuckABSTRACT Organic diallyl n-sulfide is very potential as a feed additive in preventing lipogenic in poultry. This study aims to examine the potential of diallyl n-sulfide in inhibiting lipid biosynthesis in cihateup ducks. Two hundred cihateup ducks aged 12 weeks were used in this study. Cihateup duck samples were divided into four treatment groups, each D0, without diallyl n-sulfide (Dn-S); D1, 50 µL / sample; D2, 100 µL sample and D3, 150 µL/sample, administered orally for two months of the study. Dn-S was isolated by the stratified distillation technique. Based on the results of the study showed that the administration of organic diallyl n-sulfide 150 µL/sample/ day was effective in reducing and improving the condition of plasma and liver lipids. It was concluded that diallyl n-sulfide (Dn-S) was able to reduce lipogenesis activity indicated by decreasing blood plasma and liver lipids (especially TAG), as well as increasing levels of NEFA circulating in the circulatory system. Dn-S is also able to increase lipid transport activity, namely HDL, thereby reducing cholesterol in the circulatory system but increasing its deposit in the liver tissue.Keywords: Diallyl n-Sulfide, duck, lipid

Published
2021
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5. Enhancement of the liver histologic of broiler induced by irradiated chitosan (IC).

Author

Mushawwir, Andi, Permana, Ronnie, Darwis, Darmawan, Puspitasari, Tita, Pengerteni, Dewi Sekar, Nuryanthi, Nunung, and Suwarno, Nono

Subjects
CHITOSAN, DRINKING water, CHITIN, LIVER, TREATMENT effectiveness, LIVER cells
Abstract

Two hundred and one days old, unsex broilers were used in the current study to investigate the potential of irradiated chitosan for improving histological liver, included histological condition and the activities of liver cells biochemical. Chitosan isolated from shrimp chitin using a chemical technique. The sample of broiler assigned to four groups, with five replication and each treatment group consisted of fifty of broilers. There were four treatments with supplemental irradiated chitosan (IC) by drinking water, as follow L0=without of IC; L1= IC of 300 ppm. L−1 of drinking water; L2= IC of 350 ppp.L-1 of drinking water and L3= IC of 400 ppp.L−1 of drinking water. The liver tissue samples collected using the fixative solution, and the liver samples used to determine the liver histological parameters (necrosis, apoptosis, acute inflammation, fat degeneration, hemorrhagic, hydropic degeneration) by a Mallory-asan technique, using a histological kit. The result of the current study showed that overall results indicated a significant treatment effect (P<0,05) for increasing the liver histological condition. The IC of 400 ppm can be improved the liver histologic with reduced necrosis of 31cells from 103 cells without IC. In similarly, decreased apoptosis, acute inflammation, fat degeneration, hemorrhagic, hydropic degeneration, also showed a significant with the administration of 400 ppm of IC. Based on the results of this study, The IC can reduce the damage to liver cells, and this result is an excellent indication as a biological condition in increasing the metabolic rate and performance of broilers. [ABSTRACT FROM AUTHOR]

Published
2021
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8. Profil Metabolit Plasma Darah dan Aktivitas Kreatin Kinase Sapi Perah Berdasarkan Fluktuasi Mikroklimat Lingkungan Kandangnya.

Author

Mushawwir, Andi, Yulianti, An An, Suwarno, Nono, and Permana, Ronnie

Subjects
BLOOD plasma, CREATINE kinase, HUMIDITY, GLUCONEOGENESIS, METABOLITES
Abstract

Copyright of Jurnal Veteriner is the property of Fakultas Kedokteran Hewan, Universitas Udayana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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