509 results on '"Svegliati Baroni, Gianluca"'
Search Results
2. Microwave ablation followed by cTACE in 5-cm HCC lesions: does a single-session approach affect liver function?
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Floridi, Chiara, Cacioppa, Laura Maria, Rossini, Nicolò, Macchini, Marco, Bruno, Alessandra, Agostini, Andrea, Consoli, Valeria, Inchingolo, Riccardo, Acquafredda, Fabrizio, Nicolini, Daniele, Schiadà, Laura, Svegliati Baroni, Gianluca, and Candelari, Roberto
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- 2024
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3. Suboptimal outcomes of sorafenib as a second-line treatment after atezolizumab-bevacizumab for unresectable hepatocellular carcinoma
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Tovoli, Francesco, Pallotta, Dante Pio, Vivaldi, Caterina, Campani, Claudia, Federico, Piera, Palloni, Andrea, Dalbeni, Andrea, Soldà, Caterina, Lani, Lorenzo, Svegliati-Baroni, Gianluca, Garajova, Ingrid, Ielasi, Luca, De Lorenzo, Stefania, Granito, Alessandro, Stefanini, Bernardo, Masi, Gianluca, Marra, Fabio, Lonardi, Sara, Brandi, Giovanni, Daniele, Bruno, Auriemma, Alessandra, Schiadà, Laura, Chen, Rusi, and Piscaglia, Fabio
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- 2024
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4. Hypoalbuminemia and Risk of Portal Vein Thrombosis in Cirrhosis
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Roberto Cangemi, Valeria Raparelli, Giovanni Talerico, Stefania Basili, Francesco Violi, Palasciano Giuseppe, D’Alitto Felicia, Palmieri Vincenzo Ostilio, Santovito Daniela, Di Michele Dario, Croce Giuseppe, Sacerdoti David, Brocco Silvia, Fasolato Silvano, Cecchetto Lara, Bombonato Giancarlo, Bertoni Michele, Restuccia Tea, Andreozzi Paola, Liguori Maria Livia, Perticone Francesco, Caroleo Benedetto, Perticone Maria, Staltari Orietta, Manfredini Roberto, De Giorgi Alfredo, Averna Maurizio, Giammanco Antonina, Granito Alessandro, Pettinari Irene, Marinelli Sara, Bolondi Luigi, Falsetti Lorenzo, Salvi Aldo, Durante-Mangoni Emanuele, Cesaro Flavio, Farinaro Vincenza, Ragone Enrico, Morana Ignazio, Andriulli Angelo, Ippolito Antonio, Iacobellis Angelo, Niro Grazia, Merla Antonio, Raimondo Giovanni, Maimone Sergio, Cacciola Irene, Varvara Doriana, Drenaggi Davide, Staffolani Silvia, Picardi Antonio, Vespasiani-Gentilucci Umberto, Galati Giovanni, Gallo Paolo, Davì Giovanni, Schiavone Cosima, Santilli Francesca, Tana Claudio, Licata Anna, Soresi Maurizio, Bianchi Giovanni Battista, Carderi Isabella, Pinto Antonio, Tuttolomondo Antonino, Ferrari Giovanni, Gresele Paolo, Fierro Tiziana, Morelli Olivia, Laffi Giacomo, Romanelli Roberto Giulio, Arena Umberto, Stasi Cristina, Gasbarrini Antonio, Gargovich Matteo, Zocco Maria Assunta, Riccardi Laura, Ainora Maria Elena, Capeci William, Martino Giuseppe Pio, Nobili Lorenzo, Cavallo Maurizio, Frugiuele Pierluigi, Greco Antonio, Pietrangelo Antonello, Ventura Paolo, Cuoghi Chiara, Marcacci Matteo, Serviddio Gaetano, Vendemiale Gianluigi, Villani Rosanna, Gargano Ruggiero, Vidili Gianpaolo, Di Cesare Valentina, Masala Maristella, Delitala Giuseppe, Invernizzi Pietro, Di Minno Giovanni, Tufano Antonella, Purrello Francesco, Privitera Graziella, Forgione Alessandra, Curigliano Valentina, Senzolo Marco, Rodríguez-Castro Kryssia Isabel, Giannelli Gianluigi, Serra Carla, Neri Sergio, Pignataro Pietro, Rizzetto Mario, Debernardi Venon Wilma, Svegliati Baroni Gianluca, Bergamaschi Gaetano, Masotti Michela, Costanzo Filippo, Corazza Gino Roberto, Caldwell Stephen Hugh, Angelico Francesco, Del Ben Maria, Napoleone Laura, Polimeni Licia, Proietti Marco, Raparelli Valeria, Romiti Giulio Francesco, Ruscio Eleonora, Severoni Andrea, Talerico Giovanni, Toriello Filippo, and Vestri Annarita
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Albumin ,Cirrhosis ,Portal Vein Thrombosis ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Background and Aims: Hypoalbuminemia, as defined by serum albumin (SA) levels ≤35 g/L, is associated to venous and arterial thrombosis in general population and in patients at risk of cardiovascular disease. It is unknown if SA ≤35 g/L is also associated to portal vein thrombosis (PVT) in cirrhosis. Methods: Cirrhotic patients enrolled in the Portal vein thrombosis Relevance On Liver cirrhosis: Italian Venous thrombotic Events Registry (PRO-LIVER) study (n = 753), were followed-up for 2 years to assess the risk of PVT, that was diagnosed by Doppler ultrasonography. Child-Pugh classes, Model for End-Stage Liver Disease score, presence of hepatocellular carcinoma and laboratory variables including SA, D-dimer, and high-sensitivity C-reactive protein (hs-CRP) were measured at baseline. Results: SA ≤35 g/L was detected in 52% of patients. A logistic multivariate regression analysis showed that higher Child-Pugh class, hepatocellular carcinoma and thrombocytopenia were significantly associated to SA ≤35 g/L. In a subgroup of patients where data regarding hs-CRP and D-dimer were available, SA ≤35 g/L was inversely associated with hs-CRP and D-dimer. During the follow-up, a total of 61 patients experienced PVT. A Kaplan Meier survival analysis showed SA ≤35 g/L was associated to increased risk of PVT compared to SA >35 g/L (P = .005). A multivariate Cox proportional hazards regression analysis showed that male sex, lower platelet count, and SA ≤35 g/L remained associated to PVT after adjusting for confounding factors. Conclusion: Cirrhotic patients with SA ≤35 g/L are at higher risk of experiencing PVT compared to those with SA >35 g/L and could be considered as potential candidates to anticoagulant prophylaxis for PVT prevention.
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- 2024
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5. Waiting list mortality and 5-year transplant survival benefit of patients with MASLD: An Italian liver transplant registry study
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Vitale, Alessandro, Trapani, Silvia, Russo, Francesco Paolo, Miele, Luca, Svegliati Baroni, Gianluca, Marchesini, Giulio, Burra, Patrizia, Ottoveggio, Marco Salvatore, Romagnoli, Renato, Martini, Silvia, De Simone, Paolo, Carrai, Paola, Cescon, Matteo, Morelli, Maria Cristina, De Carlis, Luciano, Belli, Luca, Gruttadauria, Salvatore, Volpes, Riccardo, Colledan, Michele, Fagiuoli, Stefano, Di Benedetto, Fabrizio, De Maria, Nicola, Rossi, Giorgio, Caccamo, Lucio, Donato, Francesca, Vennarecci, Giovanni, Di Costanzo, Giovan Giuseppe, Vivarelli, Marco, Carraro, Amedeo, Sacerdoti, David, Ettorre, Giuseppe Maria, Giannelli, Valerio, Agnes, Salvatore, Gasbarrini, Antonio, Rossi, Massimo, Ginanni Corradini, Stefano, Mazzaferro, Vincenzo, Bhoori, Sherrie, Manzia, Tommaso Maria, Lenci, Ilaria, Zamboni, Fausto, Mameli, Laura, Baccarani, Umberto, Toniutto, Pierluigi, Lupo, Luigi Giovanni, Tandoi, Francesco, Rendina, Maria, Andorno, Enzo, Giannini, Edoardo Giovanni, Spada, Marco, Billato, Ilaria, Marchini, Andrea, Romano, Pierluigi, Brancaccio, Giuseppina, D’Amico, Francesco, Ricci, Andrea, Cardillo, Massimo, and Cillo, Umberto
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- 2024
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6. Sorafenib and Metronomic Capecitabine in Child-Pugh B patients with advanced HCC: A real-life comparison with best supportive care
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Stefanini, Benedetta, Bucci, Laura, Santi, Valentina, Reggidori, Nicola, Lani, Lorenzo, Granito, Alessandro, Pelizzaro, Filippo, Cabibbo, Giuseppe, Di Marco, Mariella, Ghittoni, Giorgia, Campani, Claudia, Svegliati-Baroni, Gianluca, Foschi, Francesco Giuseppe, Giannini, Edoardo G., Biasini, Elisabetta, Saitta, Carlo, Magalotti, Donatella, Sangiovanni, Angelo, Guarino, Maria, Gasbarrini, Antonio, Rapaccini, Gian Ludovico, Masotto, Alberto, Sacco, Rodolfo, Vidili, Gianpaolo, Mega, Andrea, Azzaroli, Francesco, Nardone, Gerardo, Brandi, Giovanni, Sabbioni, Simone, Vitale, Alessandro, and Trevisani, Franco
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- 2024
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7. Subcellular distribution and Nrf2/Keap1-interacting properties of Glutathione S-transferase P in hepatocellular carcinoma
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Bartolini, Desirée, Stabile, Anna Maria, Migni, Anna, Gurrado, Fabio, Lioci, Gessica, De Franco, Francesca, Mandarano, Martina, Svegliati-Baroni, Gianluca, Di Cristina, Manlio, Bellezza, Guido, Rende, Mario, and Galli, Francesco
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- 2024
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8. Oesophageal varices predict complications in compensated advanced non-alcoholic fatty liver disease
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Pennisi, Grazia, Enea, Marco, Viganò, Mauro, Schepis, Filippo, de Ledinghen, Victor, Berzigotti, Annalisa, Wai-Sun Wong, Vincent, Fracanzani, Anna Ludovica, Sebastiani, Giada, Lara-Romero, Carmen, Bugianesi, Elisabetta, Svegliati-Baroni, Gianluca, Marra, Fabio, Aghemo, Alessio, Valenti, Luca, Calvaruso, Vincenza, Colecchia, Antonio, Di Maria, Gabriele, La Mantia, Claudia, Lin, Huapeng, Mendoza, Yuly P., Pugliese, Nicola, Ravaioli, Federico, Romero-Gomez, Manuel, Saltini, Dario, Craxì, Antonio, Di Marco, Vito, Cammà, Calogero, and Petta, Salvatore
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- 2023
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9. A global research priority agenda to advance public health responses to fatty liver disease
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Lazarus, Jeffrey V., Mark, Henry E., Allen, Alina M., Arab, Juan Pablo, Carrieri, Patrizia, Noureddin, Mazen, Alazawi, William, Alkhouri, Naim, Alqahtani, Saleh A., Arrese, Marco, Bataller, Ramon, Berg, Thomas, Brennan, Paul N., Burra, Patrizia, Castro-Narro, Graciela E., Cortez-Pinto, Helena, Cusi, Kenneth, Dedes, Nikos, Duseja, Ajay, Francque, Sven M., Hagström, Hannes, Huang, Terry T-K., Wajcman, Dana Ivancovsky, Kautz, Achim, Kopka, Christopher J., Krag, Aleksander, Miller, Veronica, Newsome, Philip N., Rinella, Mary E., Romero, Diana, Sarin, Shiv Kumar, Silva, Marcelo, Spearman, C. Wendy, Tsochatzis, Emmanuel A., Valenti, Luca, Villota-Rivas, Marcela, Zelber-Sagi, Shira, Schattenberg, Jörn M., Wong, Vincent Wai-Sun, Younossi, Zobair M., Aberg, Fredrik, Adams, Leon, Al-Naamani, Khalid, Albadawy, Reda M., Alexa, Zinaida, Allison, Michael, Alnaser, Faisal A., Alswat, Khalid, Alvares-da-Silva, Mario Reis, Alvaro, Domenico, Alves-Bezerra, Michele, Andrade, Raul J., Anstee, Quentin M., Awuku, Yaw Asante, Baatarkhuu, Oidov, Baffy, Gyorgy, Bakieva, Shokhista, Bansal, Meena B., Barouki, Robert, Batterham, Rachel L., Behling, Cynthia, Belfort-DeAguiar, Renata, Berzigotti, Annalisa, Betel, Michael, Bianco, Cristiana, Bosi, Emanuele, Boursier, Jerome, Brunt, Elizabeth M., Bugianesi, Elisabetta, Byrne, Christopher J., Cabrera Cabrejos, Maria Cecilia, Caldwell, Stephen, Carr, Rotonya, Castellanos Fernández, Marlen Ivón, Castera, Laurent, Castillo-López, Maria Gabriela, Caussy, Cyrielle, Cerda-Reyes, Eira, Ceriello, Antonio, Chan, Wah- Kheong, Chang, Yoosoo, Charatcharoenwitthaya, Phunchai, Chavez-Tapia, Norberto, Chung, Raymond T., Colombo, Massimo, Coppell, Kirsten, Cotrim, Helma P., Craxi, Antonio, Crespo, Javier, Dassanayake, Anuradha, Davidson, Nicholas O., De Knegt, Robert, de Ledinghen, Victor, Demir, Münevver, Desalegn, Hailemichael, Diago, Moises, Dillon, John F., Dimmig, Bruce, Dirac, M. Ashworth, Dirchwolf, Melisa, Dufour, Jean-François, Dvorak, Karel, Ekstedt, Mattias, El-Kassas, Mohamed, Elsanousi, Osama M., Elsharkawy, Ahmed M., Elwakil, Reda, Eskridge, Wayne, Eslam, Mohammed, Esmat, Gamal, Fan, Jian- Gao, Ferraz, Maria Lucia, Flisiak, Robert, Fortin, Davide, Fouad, Yasser, Freidman, Scott L., Fuchs, Michael, Gadano, Adrian, Gastaldelli, Amalia, Geerts, Anja, Geier, Andreas, George, Jacob, Gerber, Lynn H., Ghazinyan, Hasmik, Gheorghe, Liana, Kile, Denise Giangola, Girala, Marcos, Boon Bee, George Goh, Goossens, Nicolas, Graupera, Isabel, Grønbæk, Henning, Hamid, Saeed, Hebditch, Vanessa, Henry, Zachary, Hickman, Ingrid J., Hobbs, L. Ansley, Hocking, Samantha L., Hofmann, Wolf Peter, Idilman, Ramazan, Iruzubieta, Paula, Isaacs, Scott, Isakov, Vasily A., Ismail, Mona H., Jamal, Mohammad H., Jarvis, Helen, Jepsen, Peter, Jornayvaz, François, Sudhamshu, K.C., Kakizaki, Satoru, Karpen, Saul, Kawaguchi, Takumi, Keating, Shelley E., Khader, Yousef, Kim, Seung Up, Kim, Won, Kleiner, David E., Koek, Ger, Joseph Komas, Narcisse Patrice, Kondili, Loreta A., Koot, Bart G., Korenjak, Marko, Kotsiliti, Eleni, Koulla, Yiannoula, Kugelmas, Carina, Kugelmas, Marcelo, Labidi, Asma, Lange, Naomi F., Lavine, Joel E., Lazo, Mariana, Leite, Nathalie, Lin, Han-Chieh, Lkhagvaa, Undram, Long, Michelle T., Lopez-Jaramillo, Patricio, Lozano, Adelina, Macedo, Maria Paula, Malekzadeh, Reza, Marchesini, Giulio, Marciano, Sebastian, Martinez, Kim, Martínez Vázquez, Sophia E., Mateva, Lyudmila, Mato, José M., Nlombi, Charles Mbendi, McCary, Alexis Gorden, McIntyre, Jeff, McKee, Martin, Mendive, Juan M., Mikolasevic, Ivana, Miller, Pamela S., Milovanovic, Tamara, Milton, Terri, Moreno-Alcantar, Rosalba, Morgan, Timothy R., Motala, Ayesha, Muris, Jean, Musso, Carla, Nava-González, Edna J., Negro, Francesco, Nersesov, Alexander V., Neuschwander-Tetri, Brent A., Nikolova, Dafina, Norris, Suzanne, Novak, Katja, Ocama, Ponsiano, Ong, Janus P., Ong-Go, Arlinking, Onyekwere, Charles, Padilla, Martin, Pais, Raluca, Pan, Calvin, Panduro, Arturo, Panigrahi, Manas K., Papatheodoridis, Georgios, Paruk, Imran, Patel, Keyur, Gonçalves, Carlos Penha, Figueroa, Marlene Pérez, Pérez-Escobar, Juanita, Pericàs, Juan M., Perseghin, Gianluca, Pessoa, Mário Guimarães, Petta, Salvatore, Marques Souza de Oliveira, Claudia Pinto, Prabhakaran, Dorairaj, Pyrsopoulous, Nikolaos, Rabiee, Atoosa, Ramji, Alnoor, Ratziu, Vlad, Ravendhran, Natarajan, Ray, Katrina, Roden, Michael, Romeo, Stefano, Romero-Gómez, Manuel, Rotman, Yaron, Rouabhia, Samir, Rowe, Ian A., Sadirova, Shakhlo, Alkhatry, Maryam Salem, Salupere, Riina, Satapathy, Sanjaya K., Schwimmer, Jeffrey B., Sebastiani, Giada, Seim, Lynn, Seki, Yosuke, Serme, Abdel Karim, Shapiro, David, Sharvadze, Lali, Shaw, Jonathan E., Shawa, Isaac Thom, Shenoy, Thrivikrama, Shibolet, Oren, Shimakawa, Yusuke, Shubrook, Jay H., Singh, Shivaram Prasad, Sinkala, Edford, Skladany, Lubomir, Skrypnyk, Igor, Song, Myeong Jun, Sookoian, Silvia, Sridharan, Kannan, Stefan, Norbert, Stine, Jonathan G., Stratakis, Nikolaos, Sheriff, Dhastagir Sultan, Sundaram, Shikha S., Svegliati-Baroni, Gianluca, Swain, Mark G., Tacke, Frank, Taheri, Shahrad, Tan, Soek-Siam, Tapper, Elliot B., Targher, Giovanni, Tcaciuc, Eugen, Thiele, Maja, Tiniakos, Dina, Tolmane, Ieva, Torre, Aldo, Torres, Esther A., Treeprasertsuk, Sombat, Trenell, Michael, Turcan, Svetlana, Turcanu, Adela, Valantinas, Jonas, van Kleef, Laurens A., Velarde Ruiz Velasco, Jose Antonio, Vesterhus, Mette, Vilar-Gomez, Eduardo, Waked, Imam, Wattacheril, Julia, Wedemeyer, Heiner, Wilkins, Fonda, Willemse, José, Wong, Robert J., Yilmaz, Yusuf, Yki-Järvinen, Hannele, Yu, Ming-Lung, Yumuk, Volkan, Zeybel, Müjdat, Zheng, Kenneth I., Zheng, Ming-Hua, and Huang, Terry T.-K.
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- 2023
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10. Landscape of alcohol-related hepatocellular carcinoma in the last 15 years highlights the need to expand surveillance programs
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Biselli, Maurizio, Caraceni, Paolo, Gramenzi, Annagiulia, Benevento, Francesca, Granito, Alessandro, Muratori, Luca, Piscaglia, Fabio, Tovoli, Francesco, Allegrini, Gloria, Cammà, Calogero, Cabibbo, Giuseppe, Giacchetto, Carmelo Marco, Giuffrida, Paolo, Grassini, Maria Vittoria, Grova, Mauro, Rancatore, Gabriele, Stornello, Caterina, Adotti, Valentina, Cavoli, Tancredi Li, Marra, Fabio, Rosi, Martina, Bevilacqua, Vittoria, Borghi, Alberto, Napoli, Lucia, Conti, Fabio, Frassineti, G.L., Migliano, Maria Teresa, de Matthaeis, Nicoletta, Ponziani, Francesca Romana, Missale, Gabriele, Olivani, Andrea, Capasso, Mario, Cossiga, Valentina, Guarino, Maria, Marina Cela, Ester, Facciorusso, Antonio, Graziosi, Camilla, Lauria, Valentina, Pelecca, Giorgio, Schirripa, Marta, Chegai, Fabrizio, Raso, Armando, Bozzi, Alessio, Franzè, Maria Stella, Saitta, Carlo, Sauchella, Assunta, Dajti, Elton, Ravaioli, Federico, Plaz Torres, Maria Corina, Pieri, Giulia, Oliveri, Filippo, Ricco, Gabriele, Romagnoli, Veronica, Inno, Alessandro, Marchetti, Fabiana, Coccoli, Pietro, Malerba, Antonio, Cappelli, Alberta, Golfieri, Rita, Mosconi, Cristina, Renzulli, Matteo, Reggidori, Nicola, Bucci, Laura, Santi, Valentina, Stefanini, Benedetta, Lani, Lorenzo, Rampoldi, Davide, Ghittoni, Giorgia, Farinati, Fabio, Masotto, Alberto, Stefanini, Bernardo, Mega, Andrea, Biasini, Elisabetta, Foschi, Francesco Giuseppe, Svegliati-Baroni, Gianluca, Sangiovanni, Angelo, Campani, Claudia, Raimondo, Giovanni, Vidili, Gianpaolo, Gasbarrini, Antonio, Celsa, Ciro, Di Marco, Mariella, Giannini, Edoardo G., Sacco, Rodolfo, Brunetto, Maurizia Rossana, Azzaroli, Francesco, Magalotti, Donatella, Morisco, Filomena, Rapaccini, Gian Ludovico, Nardone, Gerardo, Vitale, Alessandro, and Trevisani, Franco
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- 2023
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11. Potential feasibility of atezolizumab-bevacizumab therapy in patients with hepatocellular carcinoma treated with tyrosine-kinase inhibitors
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Biselli, Maurizio, Caraceni, Paolo, Gramenzi, Annagiulia, Tovoli, Francesco, Granito, Alessandro, Muratori, Luca, Benevento, Francesca, Allegrini, Gloria, Cammà, Calogero, Celsa, Ciro, Giuffrida, Paolo, Stornello, Caterina, Grova, Mauro, Giacchetto, Carmelo Marco, Rancatore, Gabriele, Grassini, Maria Vittoria, Adotti, Valentina, Gitto, Stefano, Marra, Fabio, Rosi, Martina, Bevilacqua, Vittoria, Borghi, Alberto, Gardini, Andrea Casadei, Conti, Fabio, Dall'Aglio, Anna Chiara, Ercolani, Giorgio, Mirici, Federica, de Matthaeis, Nicoletta, Ponziani, Francesca Romana, Missale, Gabriele, Olivani, Andrea, Guarino, Maria, Cossiga, Valentina, Capasso, Mario, Cela, Ester Marina, Facciorusso, Antonio, Lauria, Valentina, Ghittoni, Giorgia, Pelecca, Giorgio, Chegai, Fabrizio, Coratella, Fabio, Ortenzi, Mariano, Dell'Isola, Serena, Franzè, Maria Stella, Saitta, Carlo, Sauchella, Assunta, Dajti, Elton, Ravaioli, Federico, Pieri, Giulia, Torres, Maria Corina Plaz, Oliveri, Filippo, Ricco, Gabriele, Romagnoli, Veronica, Inno, Alessandro, Marchetti, Fabiana, Coccoli, Pietro, Malerba, Antonio, Cappelli, Alberta, Golfieri, Rita, Mosconi, Cristina, Matteo Renzulli, Stefanini, Benedetta, Bucci, Laura, Santi, Valentina, Reggidori, Nicola, Rampoldi, Davide, Lani, Lorenzo, Sangiovanni, Angelo, Cabibbo, Giuseppe, Farinati, Fabio, Campani, Claudia, Foschi, Francesco Giuseppe, Svegliati-Baroni, Gianluca, Raimondo, Giovanni, Gasbarrini, Antonio, Mega, Andrea, Biasini, Elisabetta, Sacco, Rodolfo, Morisco, Filomena, Caturelli, Eugenio, Vidili, Gianpaolo, Azzaroli, Francesco, Giannini, Edoardo G., Rapaccini, Gian Ludovico, Brunetto, Maurizia Rossana, Masotto, Alberto, Nardone, Gerardo, Di Marco, Mariella, Magalotti, Donatella, and Trevisani, Franco
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- 2022
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12. Characteristics and survival of patients with primary biliary cholangitis and hepatocellular carcinoma
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Biselli, Maurizio, Caraceni, Paolo, Gramenzi, Annagiulia, Benevento, Francesca, Granito, Alessandro, Muratori, Luca, Piscaglia, Fabio, Bertellini, Federica, Farinati, Fabio, Palano, Giorgio, Pelizzaro, Filippo, Penzo, Barbara, Pinto, Elisa, Allegrini, Gloria, Cammà, Calogero, Celsa, Ciro, Giuffrida, Paolo, Stornello, Caterina, Grova, Mauro, Giacchetto, Carmelo Marco, Rancatore, Gabriele, Grassini, Maria Vittoria, Adotti, Valentina, Gitto, Stefano, Marra, Fabio, Rosi, Martina, Bevilacqua, Vittoria, Borghi, Alberto, Gardini, Andrea Casadei, Conti, Fabio, Napoli, Lucia, Domenicali, Marco, Migliano, Maria Teresa, de Matthaeis, Nicoletta, Ponziani, Francesca Romana, Olivani, Andrea, Missale, Gabriele, Cossiga, Valentina, Capasso, Mario, Morisco, Filomena, Cela, Ester Marina, Facciorusso, Antonio, Lauria, Valentina, Ghittoni, Giorgia, Pelecca, Giorgio, Chegai, Fabrizio, Coratella, Fabio, Ortenzi, Mariano, Dell'Isola, Serena, Franzè, Maria Stella, Saitta, Carlo, Sauchella, Assunta, Dajti, Elton, Ravaioli, Federico, Oliveri, Filippo, Ricco, Gabriele, Romagnoli, Veronica, Inno, Alessandro, Marchetti, Fabiana, Coccoli, Pietro, Malerba, Antonio, Cappelli, Alberta, Golfieri, Rita, Mosconi, Cristina, Renzulli, Matteo, Giannini, Edoardo G., Pieri, Giulia, Labanca, Sara, Plaz Torres, Maria Corina, Gasbarrini, Antonio, Biasini, Elisabetta, Campani, Claudia, Cazzagon, Nora, Foschi, Francesco Giuseppe, Mega, Andrea, Masotto, Alberto, Raimondo, Giovanni, Rapaccini, Gian Ludovico, Sacco, Rodolfo, Caturelli, Eugenio, Guarino, Maria, Tovoli, Francesco, Vidili, Gianpaolo, Brunetto, Maurizia Rossana, Nardone, Gerardo, Svegliati-Baroni, Gianluca, Magalotti, Donatella, Azzaroli, Francesco, Cabibbo, Giuseppe, Di Marco, Maria, Sangiovanni, Angelo, and Trevisani, Franco
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- 2022
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13. Surveillance for hepatocellular carcinoma with a 3-months interval in “extremely high-risk” patients does not further improve survival
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Biselli, Maurizio, Caraceni, Paolo, Garuti, Francesca, Gramenzi, Annagiulia, Neri, Andrea, Santi, Valentina, Piscaglia, Fabio, Tovoli, Francesco, Granito, Alessandro, Muratori, Luca, Benevento, Francesca, Dajti, Elton, Marasco, Giovanni, Ravaioli, Federico, Cappelli, Alberta, Golfieri, Rita, Mosconi, Cristina, Renzulli, Matteo, Imondi, Angela, Sartori, Anna, Penzo, Barbara, Pinto, Elisa, Cela, Ester Marina, Facciorusso, Antonio, Cacciato, Valentina, Casagrande, Edoardo, Moscatelli, Alessandro, Pellegatta, Gaia, De Matthaeis, Nicoletta, Allegrini, Gloria, Lauria, Valentina, Ghittoni, Giorgia, Pelecca, Giorgio, Chegai, Fabrizio, Coratella, Fabio, Ortenzi, Mariano, Missale, Gabriele, Inno, Alessandro, Marchetti, Fabiana, Busacca, Anita, Cabibbo, Giuseppe, Cammà, Calogero, Di Martino, Vincenzo, Rizzo, Giacomo Emanuele Maria, Franzè, Maria Stella, Saitta, Carlo, Sauchella, Assunta, Bevilacqua, Vittoria, Borghi, Alberto, Casadei Gardini, Andrea, Conti, Fabio, Dall'aglio, Anna Chiara, Ercolani, Giorgio, Mirici, Federica, Campani, Claudia, Di Bonaventura, Chiara, Gitto, Stefano, Coccoli, Pietro, Malerba, Antonio, Guarino, Maria, Brunetto, Maurizia, Romagnoli, Veronica, Pelizzaro, Filippo, Peserico, Giulia, D'Elia, Marco, Cazzagon, Nora, Russo, Francesco Paolo, Vitale, Alessandro, Giannini, Edoardo G., Piccinnu, Manuela, Rapaccini, Gian Ludovico, Di Marco, Maria, Caturelli, Eugenio, Zoli, Marco, Sacco, Rodolfo, Marra, Fabio, Mega, Andrea, Morisco, Filomena, Gasbarrini, Antonio, Svegliati-Baroni, Gianluca, Foschi, Francesco Giuseppe, Olivani, Andrea, Masotto, Alberto, Nardone, Gerardo, Raimondo, Giovanni, Azzaroli, Francesco, Vidili, Gianpaolo, Oliveri, Filippo, Trevisani, Franco, and Farinati, Fabio
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- 2022
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14. Comparison of point shear wave elastography and transient elastography in the evaluation of patients with NAFLD
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Argalia, Giulio, Ventura, Claudio, Tosi, Niccolò, Campioni, Daniele, Tagliati, Corrado, Tufillaro, Marianna, Cucco, Monica, Svegliati Baroni, Gianluca, and Giovagnoni, Andrea
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- 2022
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15. Non-alcoholic fatty liver disease in adults 2021: A clinical practice guideline of the Italian Association for the Study of the Liver (AISF), the Italian Society of Diabetology (SID) and the Italian Society of Obesity (SIO)
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Marchesini, Giulio, Bugianesi, Elisabetta, Burra, Patrizia, Marra, Fabio, Miele, Luca, Alisi, Anna, Vajro, Piero, Masarone, Mario, Petta, Salvatore, Persico, Marcello, Svegliati-Baroni, Gianluca, Valenti, Luca, Federici, Massimo, Purrello, Francesco, Sasso, Ferdinando Carlo, Targher, Giovanni, Busetto, Luca, Petroni, Maria Letizia, Santini, Ferruccio, Cammà, Calogero, and Colli, Agostino
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- 2022
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16. THU-161 Hepatic sarcoidosis diagnosis and management: an italian multicenter study
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Corte, Cristina Della, primary, D'Amato, Daphne, additional, Rocchetti, Adele, additional, Viganò, Mauro, additional, Martini, Andrea, additional, Morelli, Maria Cristina, additional, Terracciani, Francesca, additional, Campigotto, Michele, additional, Pugliese, Nicola, additional, Giannini, Edoardo, additional, Simone, Loredana, additional, Malinverno, Federica, additional, Reati, Raffaella, additional, Degasperi, Elisabetta, additional, Federico, Alessandro, additional, Mangoni, Emanuele Durante, additional, Missale, Gabriele, additional, Svegliati-Baroni, Gianluca, additional, Morana, Ester, additional, Rapetti, Rachele, additional, Lorenzo, Surace, additional, Arena, Ilaria, additional, Cespiati, Annalisa, additional, Del Poggio, Paolo, additional, Germani, Giacomo, additional, Marin, Renato, additional, Federica, Mirici, additional, Rosaria, Piras Maria, additional, Perricone, Giovanni, additional, Sciarrone, Salvatore, additional, Rendina, Maria Grazia, additional, Strona, Silvia, additional, Giampaolo, Luca, additional, Montagnese, Sara, additional, Saibeni, Simone, additional, Manes, Giampiero, additional, and Carbone, Marco, additional
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- 2024
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17. THU-472-YI Sorafenib as a second-line treatment after failure of Atezolizumab/Bevacizumab
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Tovoli, Francesco, primary, Boe, Maria, additional, Vivaldi, Caterina, additional, Federico, Piera, additional, Palloni, Andrea, additional, Dalbeni, Andrea, additional, Soldà, Caterina, additional, Stefanini, Benedetta, additional, Garajovà, Ingrid, additional, Ielasi, Luca, additional, De Lorenzo, Stefania, additional, Granito, Alessandro, additional, Stefanini, Bernardo, additional, Masi, Gianluca, additional, Lonardi, Sara, additional, Brandi, Giovanni, additional, Bruno, Daniele, additional, Auriemma, Alessandra, additional, Lani, Lorenzo, additional, Campani, Claudia, additional, Svegliati-Baroni, Gianluca, additional, and Piscaglia, Fabio, additional
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- 2024
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18. WED-293 Effectiveness of on different models of care based on Fibrosis-4 and/or liver stiffness measurement for the screening of patients with type 2 diabetes mellitus at risk of advanced liver disease
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Caviglia, Gian Paolo, primary, Ferro, Arianna, additional, Armandi, Angelo, additional, D'Ambrosio, Roberta, additional, Lampertico, Pietro, additional, Periti, Giulia, additional, Valenti, Luca, additional, Ciccioli, Carlo, additional, Pennisi, Grazia, additional, Petta, Salvatore, additional, Brodosi, Lucia, additional, Petroni, Maria Letizia, additional, Marchignoli, Francesca, additional, Pironi, Loris, additional, Sagripanti, Alessandra, additional, Argenziano, Maria Eva, additional, Svegliati-Baroni, Gianluca, additional, Gruden, Gabriella, additional, and Bugianesi, Elisabetta, additional
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- 2024
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19. SAT-477-YI The impact of etiologyon patterns of progression of advanced HCC
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Stefanini, Bernardo, primary, Piscaglia, Fabio, additional, Dalbeni, Andrea, additional, Vivaldi, Caterina, additional, Federico, Piera, additional, Palloni, Andrea, additional, Soldà, Caterina, additional, Stefanini, Benedetta, additional, Garajova, Ingrid, additional, Ielasi, Luca, additional, De Lorenzo, Stefania, additional, Masi, Gianluca, additional, Lonardi, Sara, additional, Brandi, Giovanni, additional, Daniele, Bruno, additional, Trevisani, Franco, additional, Svegliati-Baroni, Gianluca, additional, Campani, Claudia, additional, Chen, Rusi, additional, and Tovoli, Francesco, additional
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- 2024
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20. Global prevalence of MAFLD-related hepatocellular carcinoma: A systematic review and meta-analysis
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Crane, Harry, primary, Eslick, Guy D., additional, Gofton, Cameron, additional, Shaikh, Anjiya, additional, Cholankeril, George, additional, Cheah, Mark, additional, Zhong, Jian-Hong, additional, Svegliati-Baroni, Gianluca, additional, Vitale, Alessandro, additional, Kim, Beom Kyung, additional, Ahn, Sang Hoon, additional, Kim, Mi Na, additional, Strasser, Simone, additional, and George, Jacob, additional
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- 2024
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21. Research Strands in Dermatology and Gastroenterology Units of Department of Clinical and Molecular Sciences in Polytechnic Marche University
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Benedetti, Antonio, Campanati, Anna, Martina, Emanuela, Simonetti, Oriana, Bendia, Emanuele, Di Sario, Antonio, Maroni, Luca, Marzioni, Marco, Pierantonelli, Irene, Sassaroli, Paola, Schiadà, Laura, Svegliati-Baroni, Gianluca, Tarantino, Giuseppe, Offidani, Annamaria, Longhi, Sauro, editor, Monteriù, Andrea, editor, Freddi, Alessandro, editor, Aquilanti, Lucia, editor, Ceravolo, Maria Gabriella, editor, Carnevali, Oliana, editor, Giordano, Mario, editor, and Moroncini, Gianluca, editor
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- 2020
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22. Material deprivation affects the management and clinical outcome of hepatocellular carcinoma in a high-resource environment
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Avanzato, Francesca, Biselli, Maurizio, Caraceni, Paolo, Garuti, Francesca, Gramenzi, Annagiulia, Neri, Andrea, Santi, Valentina, Pellizzaro, Filippo, Imondi, Angela, Sartori, Anna, Penzo, Barbara, Sanmarco, Ambra, Granito, Alessandro, Muratori, Luca, Piscaglia, Fabio, Sansone, Vito, Forgione, Antonella, Dajti, Elton, Marasco, Giovanni, Ravaioli, Federico, Cappelli, Alberta, Golfieri, Rita, Mosconi, Cristina, Renzulli, Matteo, Cela, Ester Marina, Facciorusso, Antonio, Cacciato, Valentina, Casagrande, Edoardo, Moscatelli, Alessandro, Pellegatta, Gaia, de Matthaeis, Nicoletta, Allegrini, Gloria, Lauria, Valentina, Ghittoni, Giorgia, Pelecca, Giorgio, Chegai, Fabrizio, Coratella, Fabio, Ortenzi, Mariano, Missale, Gabriele, Olivani, Andrea, Inno, Alessandro, Marchetti, Fabiana, Busacca, Anita, Cabibbo, Giuseppe, Cammà, Calogero, Di Martino, Vincenzo, Maria Rizzo, Giacomo Emanuele, Franzè, Maria Stella, Saitta, Carlo, Sauchella, Assunta, Berardinelli, Dante, Bevilacqua, Vittoria, Borghi, Alberto, Gardini, Andrea Casadei, Conti, Fabio, Dall'Aglio, Anna Chiara, Ercolani, Giorgio, Adotti, Valentina, Arena, Umberto, Di Bonaventura, Chiara, Campani, Claudia, Dragoni, Gabriele, Gitto, Stefano, Laffi, Giacomo, Coccoli, Pietro, Malerba, Antonio, Guarino, Maria, Capasso, Maria, Oliveri, Filippo, Romagnoli, Veronica, Cucchetti, Alessandro, Johnson, Philip, Giannini, Edoardo G., Tovoli, Francesco, Rapaccini, Gian Ludovico, Marra, Fabio, Caturelli, Eugenio, Gasbarrini, Antonio, Svegliati-Baroni, Gianluca, Sacco, Rodolfo, Zoli, Marco, Morisco, Filomena, Di Marco, Maria, Mega, Andrea, Foschi, Francesco G., Biasini, Elisabetta, Masotto, Alberto, Nardone, Gerardo, Raimondo, Giovanni, Azzaroli, Francesco, Vidili, Gianpaolo, Brunetto, Maurizia R., Farinati, Fabio, and Trevisani, Franco
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- 2021
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23. On-treatment serum albumin level can guide long-term treatment in patients with cirrhosis and uncomplicated ascites
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Domenicali, Marco, Giannone, Ferdinando A., Antognoli, Agnese, Merli, Manuela, Pasquale, Chiara, Gioia, Stefania, Fasolato, Silvano, Sticca, Antonietta, Campion, Daniela, Risso, Alessandro, Saracco, Giorgio M., Prestianni, Loredana, Fidone, Federica, Maiorca, Daniela, Rizzotto, Agostino, Cappa, Federica Mirici, Lanzi, Arianna, Neri, Elga, Visani, Anna, Mastroianni, Antonio, Perricone, Giovanni, Alberti, Alberto B., Cesarini, Lucia, Mazzarelli, Chiara, Vangeli, Marcello, Viganò, Raffaella, Marzioni, Marco, Capretti, Francesca, Kostandini, Alba, Magini, Giulia, Colpani, Maria, Gabbani, Tommaso, Marsico, Maria, Zappimbulso, Marianna, Petruzzi, Josè, Calvaruso, Vincenza, Parrella, Giovanni, Caporaso, Nicola, Auriemma, Francesco, Guarino, Maria, Pugliese, Fabio, Tortora, Annalisa, Leo, Pietro, Angelico, Mario, De Leonardis, Francesco, Pecchioli, Alessandra, Rossi, Piera, Raimondo, Giovanni, Cacciola, Irene, Elia, Gianfranco, Negri, Elisa, Dallio, Marcello, Loguercio, Carmelina, Federico, Alessandro, Conte, Dario, Massironi, Sara, Natascia Celli, Giorgio Ballardini, Rendina, Maria, Bringiotti, Roberto, Castellaneta, Nicola Maurizio, Salerno, Francesco, Boccia, Sergio, Guarisco, Riccardo, Galioto, Alessandra, Cavallin, Marta, Andrealli, Alida, Caraceni, Paolo, Tufoni, Manuel, Zaccherini, Giacomo, Riggio, Oliviero, Angeli, Paolo, Alessandria, Carlo, Neri, Sergio, Foschi, Francesco G., Levantesi, Fabio, Airoldi, Aldo, Simone, Loredana, Svegliati-Baroni, Gianluca, Fagiuoli, Stefano, Laffi, Giacomo, Cozzolongo, Raffaele, Di Marco, Vito, Sangiovanni, Vincenzo, Morisco, Filomena, Toniutto, Pierluigi, Gasbarrini, Antonio, De Marco, Rosanna, Piano, Salvatore, Nardelli, Silvia, Elia, Chiara, Roncadori, Andrea, Baldassarre, Maurizio, and Bernardi, Mauro
- Published
- 2021
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24. Global prevalence of metabolic dysfunction-associated fatty liver disease-related hepatocellular carcinoma: A systematic review and meta-analysis.
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Crane, Harry, Eslick, Guy D., Gofton, Cameron, Shaikh, Anjiya, Cholankeril, George, Cheah, Mark, Zhong, Jian-Hong, Svegliati-Baroni, Gianluca, Vitale, Alessandro, Kim, Beom Kyung, Ahn, Sang Hoon, Kim, Mi Na, Strasser, Simone I, and George, Jacob
- Published
- 2024
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25. Characteristics and outcome of anti-hepatitis D virus positive patients with hepatocellular carcinoma.
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Giannini, Edoardo G., Pasta, Andrea, Pieri, Giulia, Plaz Torres, Maria Corina, Marseglia, Mariarosaria, Pelizzaro, Filippo, Sangiovanni, Angelo, Cabibbo, Giuseppe, Ghittoni, Giorgia, Di Marco, Mariella, Foschi, Francesco Giuseppe, Guarino, Maria, Biasini, Elisabetta, Saitta, Carlo, Campani, Claudia, Svegliati-Baroni, Gianluca, Gasbarrini, Antonio, Brunetto, Maurizia Rossana, Magalotti, Donatella, and Azzaroli, Francesco
- Subjects
HEPATITIS D virus ,HEPATOCELLULAR carcinoma ,CHRONIC active hepatitis ,HEPATITIS B virus ,CANCER patients - Abstract
Background & Aims: Chronic hepatitis D virus (HDV) often leads to end-stage liver disease and hepatocellular carcinoma (HCC). Comprehensive data pertaining to large populations with HDV and HCC are missing, therefore we sought to assess the characteristics, management, and outcome of these patients, comparing them to patients with hepatitis B virus (HBV) infection. Methods: We analysed the Italian Liver Cancer database focusing on patients with positivity for HBV surface antigen and anti-HDV antibodies (HBV/HDV, n = 107) and patients with HBV infection alone (n = 588). Clinical and oncological characteristics, treatment, and survival were compared in the two groups. Results: Patients with HBV/HDV had worse liver function [Model for End-stage Liver Disease score: 11 vs. 9, p<.0001; Child-Turcotte-Pugh score: 7 vs. 5, p<.0001] than patients with HBV. HCC was more frequently diagnosed during surveillance (72.9% vs. 52.4%, p = .0002), and the oncological stage was more frequently Milan-in (67.3% vs. 52.7%, p = .005) in patients with HBV/HDV. Liver transplantation was more frequently performed in HBV/HDV than in HBV patients (36.4% vs. 9.5%), while the opposite was observed for resection (8.4% vs. 20.1%, p<.0001), and in a competing risk analysis, HBV/HDV patients had a higher probability of receiving transplantation, independently of liver function and oncological stage. A trend towards longer survival was observed in patients with HBV/HDV (50.4 vs. 44.4months, p = .106). Conclusions: In patients with HBV/HDV, HCC is diagnosed more frequently during surveillance, resulting in a less advanced cancer stage in patients with more deranged liver function than HBV alone. Patients with HBV/HDV have a heightened benefit from liver transplantation, positively influencing survival. [ABSTRACT FROM AUTHOR]
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- 2024
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26. Liver transplantation in hepatocellular carcinoma after tumour downstaging (XXL): a randomised, controlled, phase 2b/3 trial
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Mazzaferro, Vincenzo, Citterio, Davide, Bhoori, Sherrie, Bongini, Marco, Miceli, Rosalba, De Carlis, Luciano, Colledan, Michele, Salizzoni, Mauro, Romagnoli, Renato, Antonelli, Barbara, Vivarelli, Marco, Tisone, Giuseppe, Rossi, Massimo, Gruttadauria, Salvatore, Di Sandro, Stefano, De Carlis, Riccardo, Lucà, Maria Grazia, De Giorgio, Massimo, Mirabella, Stefano, Belli, Luca, Fagiuoli, Stefano, Martini, Silvia, Iavarone, Massimo, Svegliati Baroni, Gianluca, Angelico, Mario, Ginanni Corradini, Stefano, Volpes, Riccardo, Mariani, Luigi, Regalia, Enrico, Flores, Maria, Droz dit Busset, Michele, and Sposito, Carlo
- Published
- 2020
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27. Lipidomic biomarkers and mechanisms of lipotoxicity in non-alcoholic fatty liver disease
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Svegliati-Baroni, Gianluca, Pierantonelli, Irene, Torquato, Pierangelo, Marinelli, Rita, Ferreri, Carla, Chatgilialoglu, Chryssostomos, Bartolini, Desirée, and Galli, Francesco
- Published
- 2019
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28. List of contributors
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Alterini, Giada, primary, Bassotti, Gabrio, additional, Bellini, Massimo, additional, Blaga, Teodora Surdea, additional, Blandizzi, Corrado, additional, Brillanti, Stefano, additional, Bronzini, Francesco, additional, Colucci, Rocchina, additional, Dumitrascu, Dan L., additional, D’Mello, Charlotte, additional, Fianchi, Francesca, additional, Fornai, Matteo, additional, Galli, Andrea, additional, Grad, Simona, additional, Kim, Yong-Ku, additional, Laguna de la Vera, Anna-Lena, additional, Maroni, Luca, additional, Miele, Luca, additional, Milani, Stefano, additional, Pfeilschifter, Waltraud, additional, Pop, Andrei V., additional, Samanta, Sandip, additional, Scalese, Giulia, additional, Severi, Carola, additional, Shawcross, Debbie L., additional, Shin, Cheolmin, additional, Stasi, Cristina, additional, Svegliati Baroni, Gianluca, additional, Swain, Mark G., additional, Trebicka, Jonel, additional, Usai Satta, Paolo, additional, and Welsch, Christoph, additional
- Published
- 2021
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29. The pathophysiology of gut–liver connection
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Maroni, Luca, primary, Fianchi, Francesca, additional, Miele, Luca, additional, and Svegliati Baroni, Gianluca, additional
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- 2021
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30. Further decompensation in cirrhosis: Results of a large multicenter cohort study supporting Baveno VII statements
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D’Amico, Gennaro, primary, Zipprich, Alexander, additional, Villanueva, Càndid, additional, Sordà, Juan Antonio, additional, Morillas, Rosa Maria, additional, Garcovich, Matteo, additional, García Retortillo, Montserrat, additional, Martinez, Javier, additional, Calès, Paul, additional, D’Amico, Mario, additional, Dollinger, Matthias, additional, García-Guix, Marta, additional, Gonzalez Ballerga, Esteban, additional, Tsochatzis, Emmanuel, additional, Cirera, Isabel, additional, Albillos, Agustìn, additional, Roquin, Guillaume, additional, Pasta, Linda, additional, Colomo, Alan, additional, Daruich, Jorge, additional, Canete, Nuria, additional, Boursier, Jérôme, additional, Dallio, Marcello, additional, Gasbarrini, Antonio, additional, Iacobellis, Angelo, additional, Gobbo, Giulia, additional, Merli, Manuela, additional, Federico, Alessandro, additional, Svegliati Baroni, Gianluca, additional, Pozzoni, Pietro, additional, Addario, Luigi, additional, Chessa, Luchino, additional, Ridola, Lorenzo, additional, and Garcia-Tsao, Guadalupe, additional
- Published
- 2023
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31. Long-term albumin administration in decompensated cirrhosis (ANSWER): an open-label randomised trial
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Domenicali, Marco, Giannone, Ferdinando A, Merli, Manuela, Gioia, Stefania, Fasolato, Silvano, Sticca, Antonietta, Campion, Daniela, Risso, Alessandro, Saracco, Giorgio M, Maiorca, Daniela, Rizzotto, Agostino, Lanzi, Arianna, Neri, Elga, Visani, Anna, Mastroianni, Antonio, Alberti, Alberto B, Mazzarelli, Chiara, Vangeli, Marcello, Marzioni, Marco, Capretti, Francesca, Kostandini, Alba, Magini, Giulia, Colpani, Maria, Laffi, Giacomo, Gabbani, Tommaso, Marsico, Maria, Zappimbulso, Marianna, Petruzzi, Josè, Calvaruso, Vincenza, Parrella, Giovanni, Caporaso, Nicola, Auriemma, Francesco, Guarino, Maria, Pugliese, Fabio, Gasbarrini, Antonio, Leo, Pietro, De Leonardis, Francesco, Pecchioli, Alessandra, Rossi, Piera, Raimondo, Giovanni, Negri, Elisa, Dallio, Marcello, Loguercio, Carmelina, Conte, Dario, Celli, Natascia, Bringiotti, Roberto, Castellaneta, Nicola M, Salerno, Francesco, Caraceni, Paolo, Riggio, Oliviero, Angeli, Paolo, Alessandria, Carlo, Neri, Sergio, Foschi, Francesco G, Levantesi, Fabio, Airoldi, Aldo, Boccia, Sergio, Svegliati-Baroni, Gianluca, Fagiuoli, Stefano, Romanelli, Roberto G, Cozzolongo, Raffaele, Di Marco, Vito, Sangiovanni, Vincenzo, Morisco, Filomena, Toniutto, Pierluigi, Tortora, Annalisa, De Marco, Rosanna, Angelico, Mario, Cacciola, Irene, Elia, Gianfranco, Federico, Alessandro, Massironi, Sara, Guarisco, Riccardo, Galioto, Alessandra, Ballardini, Giorgio, Rendina, Maria, Nardelli, Silvia, Piano, Salvatore, Elia, Chiara, Prestianni, Loredana, Cappa, Federica Mirici, Cesarini, Lucia, Simone, Loredana, Pasquale, Chiara, Cavallin, Marta, Andrealli, Alida, Fidone, Federica, Ruggeri, Matteo, Roncadori, Andrea, Baldassarre, Maurizio, Tufoni, Manuel, Zaccherini, Giacomo, and Bernardi, Mauro
- Published
- 2018
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32. Utility of Tumor Burden Score to Stratify Prognosis of Patients with Hepatocellular Cancer: Results of 4759 Cases from ITA.LI.CA Study Group
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Vitale, Alessandro, Lai, Quirino, Farinati, Fabio, Bucci, Laura, Giannini, Edoardo G., Napoli, Lucia, Ciccarese, Francesca, Rapaccini, Gian Lodovico, Di Marco, Maria, Caturelli, Eugenio, Zoli, Marco, Borzio, Franco, Sacco, Rodolfo, Cabibbo, Giuseppe, Virdone, Roberto, Marra, Fabio, Felder, Martina, Morisco, Filomena, Benvegnù, Luisa, Gasbarrini, Antonio, Svegliati-Baroni, Gianluca, Foschi, Francesco Giuseppe, Missale, Gabriele, Masotto, Alberto, Nardone, Gerardo, Colecchia, Antonio, Bernardi, Mauro, Trevisani, Franco, and Pawlik, Timothy M.
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- 2018
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33. Lipotoxicity and the gut-liver axis in NASH pathogenesis
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Marra, Fabio and Svegliati-Baroni, Gianluca
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- 2018
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34. Brivanib in combination with Notch3 silencing shows potent activity in tumour models
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Giovannini, Catia, Salzano, Anna Maria, Baglioni, Michele, Vitale, Monica, Scaloni, Andrea, Zambrano, Nicola, Giannone, Ferdinando Antonio, Vasuri, Francesco, D’Errico, Antonia, Svegliati Baroni, Gianluca, Bolondi, Luigi, and Gramantieri, Laura
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- 2019
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35. Perspective on the Role of Gut Microbiome in the Treatment of Hepatocellular Carcinoma with Immune Checkpoint Inhibitors
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Abenavoli, Ludovico, primary, Montori, Michele, additional, Svegliati Baroni, Gianluca, additional, Argenziano, Maria Eva, additional, Giorgi, Francesca, additional, Scarlata, Giuseppe Guido Maria, additional, Ponziani, Francesca, additional, and Scarpellini, Emidio, additional
- Published
- 2023
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36. Landscape of alcohol-related hepatocellular carcinoma in the last 15 years highlights the need to expand surveillance programs
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Reggidori, Nicola, primary, Bucci, Laura, additional, Santi, Valentina, additional, Stefanini, Benedetta, additional, Lani, Lorenzo, additional, Rampoldi, Davide, additional, Ghittoni, Giorgia, additional, Farinati, Fabio, additional, Masotto, Alberto, additional, Stefanini, Bernardo, additional, Mega, Andrea, additional, Biasini, Elisabetta, additional, Foschi, Francesco Giuseppe, additional, Svegliati-Baroni, Gianluca, additional, Sangiovanni, Angelo, additional, Campani, Claudia, additional, Raimondo, Giovanni, additional, Vidili, Gianpaolo, additional, Gasbarrini, Antonio, additional, Celsa, Ciro, additional, Di Marco, Mariella, additional, Giannini, Edoardo G., additional, Sacco, Rodolfo, additional, Brunetto, Maurizia Rossana, additional, Azzaroli, Francesco, additional, Magalotti, Donatella, additional, Morisco, Filomena, additional, Rapaccini, Gian Ludovico, additional, Nardone, Gerardo, additional, Vitale, Alessandro, additional, Trevisani, Franco, additional, Biselli, Maurizio, additional, Caraceni, Paolo, additional, Gramenzi, Annagiulia, additional, Benevento, Francesca, additional, Granito, Alessandro, additional, Muratori, Luca, additional, Piscaglia, Fabio, additional, Tovoli, Francesco, additional, Allegrini, Gloria, additional, Cammà, Calogero, additional, Cabibbo, Giuseppe, additional, Giacchetto, Carmelo Marco, additional, Giuffrida, Paolo, additional, Grassini, Maria Vittoria, additional, Grova, Mauro, additional, Rancatore, Gabriele, additional, Stornello, Caterina, additional, Adotti, Valentina, additional, Cavoli, Tancredi Li, additional, Marra, Fabio, additional, Rosi, Martina, additional, Bevilacqua, Vittoria, additional, Borghi, Alberto, additional, Napoli, Lucia, additional, Conti, Fabio, additional, Frassineti, G.L., additional, Migliano, Maria Teresa, additional, de Matthaeis, Nicoletta, additional, Ponziani, Francesca Romana, additional, Missale, Gabriele, additional, Olivani, Andrea, additional, Capasso, Mario, additional, Cossiga, Valentina, additional, Guarino, Maria, additional, Marina Cela, Ester, additional, Facciorusso, Antonio, additional, Graziosi, Camilla, additional, Lauria, Valentina, additional, Pelecca, Giorgio, additional, Schirripa, Marta, additional, Chegai, Fabrizio, additional, Raso, Armando, additional, Bozzi, Alessio, additional, Franzè, Maria Stella, additional, Saitta, Carlo, additional, Sauchella, Assunta, additional, Dajti, Elton, additional, Ravaioli, Federico, additional, Plaz Torres, Maria Corina, additional, Pieri, Giulia, additional, Oliveri, Filippo, additional, Ricco, Gabriele, additional, Romagnoli, Veronica, additional, Inno, Alessandro, additional, Marchetti, Fabiana, additional, Coccoli, Pietro, additional, Malerba, Antonio, additional, Cappelli, Alberta, additional, Golfieri, Rita, additional, Mosconi, Cristina, additional, and Renzulli, Matteo, additional
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- 2023
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37. The Italian data on SARS-CoV-2 infection in transplanted patients support an organ specific immune response in liver recipients
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Rendina, Maria, primary, Barone, Michele, additional, Lillo, Chiara, additional, Trapani, Silvia, additional, Masiero, Lucia, additional, Trerotoli, Paolo, additional, Puoti, Francesca, additional, Lupo, Luigi Giovanni, additional, Tandoi, Francesco, additional, Agnes, Salvatore, additional, Grieco, Antonio, additional, Andorno, Enzo, additional, Marenco, Simona, additional, Giannini, Edoardo Giovanni, additional, Baccarani, Umberto, additional, Toniutto, Pierluigi, additional, Carraro, Amedeo, additional, Colecchia, Antonio, additional, Cescon, Matteo, additional, Morelli, Maria Cristina, additional, Cillo, Umberto, additional, Burra, Patrizia, additional, Angeli, Paolo, additional, Colledan, Michele, additional, Fagiuoli, Stefano, additional, De Carlis, Luciano, additional, Belli, Luca, additional, De Simone, Paolo, additional, Carrai, Paola, additional, Di Benedetto, Fabrizio, additional, De Maria, Nicola, additional, Ettorre, Giuseppe Maria, additional, Giannelli, Valerio, additional, Gruttadauria, Salvatore, additional, Volpes, Riccardo, additional, Corsale, Sveva, additional, Mazzaferro, Vincenzo, additional, Bhoori, Sherrie, additional, Romagnoli, Renato, additional, Martini, Silvia, additional, Rossi, Giorgio, additional, Caccamo, Lucio, additional, Donato, Maria Francesca, additional, Rossi, Massimo, additional, Ginanni Corradini, Stefano, additional, Spada, Marco, additional, Maggiore, Giuseppe, additional, Tisone, Giuseppe, additional, Lenci, Ilaria, additional, Vennarecci, Giovanni, additional, Tortora, Raffaella, additional, Vivarelli, Marco, additional, Svegliati Baroni, Gianluca, additional, Zamboni, Fausto, additional, Mameli, Laura, additional, Tafuri, Silvio, additional, Simone, Simona, additional, Gesualdo, Loreto, additional, Cardillo, Massimo, additional, and Di Leo, Alfredo, additional
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- 2023
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38. Nonalcoholic fatty liver disease impairs the cytochrome P-450-dependent metabolism of α-tocopherol (vitamin E)
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Bartolini, Desirée, Torquato, Pierangelo, Barola, Carolina, Russo, Angelo, Rychlicki, Chiara, Giusepponi, Danilo, Bellezza, Guido, Sidoni, Angelo, Galarini, Roberta, Svegliati-Baroni, Gianluca, and Galli, Francesco
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- 2017
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39. Hepatic decompensation is the major driver of death in HCV-infected cirrhotic patients with successfully treated early hepatocellular carcinoma
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Cabibbo, Giuseppe, Petta, Salvatore, Barbara, Marco, Attardo, Simona, Bucci, Laura, Farinati, Fabio, Giannini, Edoardo G., Negrini, Giulia, Ciccarese, Francesca, Rapaccini, Gian Lodovico, Di Marco, Maria, Caturelli, Eugenio, Zoli, Marco, Borzio, Franco, Sacco, Rodolfo, Virdone, Roberto, Marra, Fabio, Mega, Andrea, Morisco, Filomena, Benvegnù, Luisa, Gasbarrini, Antonio, Svegliati-Baroni, Gianluca, Foschi, Francesco Giuseppe, Olivani, Andrea, Masotto, Alberto, Nardone, Gerardo, Colecchia, Antonio, Persico, Marcello, Craxì, Antonio, Trevisani, Franco, and Cammà, Calogero
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- 2017
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40. AISF position paper on nonalcoholic fatty liver disease (NAFLD): Updates and future directions
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Lonardo, Amedeo, Nascimbeni, Fabio, Targher, Giovanni, Bernardi, Mauro, Bonino, Ferruccio, Bugianesi, Elisabetta, Casini, Alessandro, Gastaldelli, Amalia, Marchesini, Giulio, Marra, Fabio, Miele, Luca, Morisco, Filomena, Petta, Salvatore, Piscaglia, Fabio, Svegliati-Baroni, Gianluca, Valenti, Luca, and Bellentani, Stefano
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- 2017
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41. Prophylaxis of HBV-recurrence after liver transplantation in patients with HCC: risk of HCC recurrence from a large, multicentre retrospective study from Italy
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Burra, Patrizia, primary, Battistella, Sara, additional, Russo, Francesco Paolo, additional, Turco, Laura, additional, Manuli, Chiara, additional, Calleri, Alberto, additional, Pasulo, Luisa, additional, Giannelli, Valerio, additional, DiBenedetto, Clara, additional, Mameli, Laura, additional, Ferrarese, Alberto, additional, Marenco, Simona, additional, Ferri, Flaminia, additional, Lenci, Ilaria, additional, Forastiere, Domenico, additional, Schiavone, Silvia, additional, Vero, Vittoria, additional, Vizioli, Luca, additional, Carroli, Agnese, additional, Frassanito, Gabriella, additional, Scandali, Giulia, additional, Biolato, Marco, additional, Fornasiere, Ezio, additional, Ponziani, Francesca, additional, Svegliati-Baroni, Gianluca, additional, Giannini, Edoardo Giovanni, additional, Toniutto, Pierluigi, additional, Lanza, Alfonso Galeota, additional, Rendina, Maria Grazia, additional, Donato, Maria Francesca, additional, Fagiuoli, Stefano, additional, De Maria, Nicola, additional, Morelli, Maria Cristina, additional, Martini, Silvia, additional, Trapani, Silvia, additional, Grossi, Paolo Antonio, additional, Aghemo, Alessio, additional, and Zanetto, Alberto, additional
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- 2023
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42. Primary sclerosing cholangitis recurrence after liver transplantation: a nationwide survey in Italy
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Morelli, Maria Cristina, primary, Gambato, Martina, additional, Martini, Silvia, additional, Carrai, Paola, additional, Toniutto, Pierluigi, additional, Giannelli, Valerio, additional, Donato, Maria Francesca, additional, Lenci, Ilaria, additional, Pasulo, Luisa, additional, Mazzarelli, Chiara, additional, Ferrarese, Alberto, additional, Rendina, Maria Grazia, additional, Grieco, Antonio, additional, Lanza, Alfonso Galeota, additional, Svegliati-Baroni, Gianluca, additional, De Maria, Nicola, additional, Mameli, Laura, additional, Marenco, Simona, additional, and Burra, Patrizia, additional
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- 2023
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43. Presence and severity of esophageal varices drives portal hypertension-related complications in compensated advanced non-alcoholic fatty liver disease
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Pennisi, Grazia, primary, Enea, Marco, additional, Viganò, Mauro, additional, Schepis, Filippo, additional, de Lédinghen, Victor, additional, Berzigotti, Annalisa, additional, Wong, Vincent Wai-Sun, additional, Fracanzani, Anna Ludovica, additional, Sebastiani, Giada, additional, Gomez, Manuel Romero, additional, Bugianesi, Elisabetta, additional, Svegliati-Baroni, Gianluca, additional, Marra, Fabio, additional, Aghemo, Alessio, additional, Valenti, Luca, additional, Calvaruso, Vincenza, additional, Colecchia, Antonio, additional, Di Maria, Gabriele, additional, La Mantia, Claudia, additional, Lin, Huapeng, additional, Mendoza, Yuly, additional, Pugliese, Nicola, additional, Ravaioli, Federico, additional, Lara-Romero, Carmen, additional, Saltini, Dario, additional, Craxi, Antonio, additional, Di Marco, Vito, additional, Camma, Calogero, additional, and Petta, Salvatore, additional
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- 2023
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44. Further decompensation as a new prognostic stage in cirrhosis. Results of a large multicenter cohort study supporting Baveno VII statements
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D’Amico, Gennaro, primary, Garcia-Tsao, Guadalupe, additional, Zipprich, Alexander, additional, Villanueva, Càndid, additional, Sorda, Juan Antonio, additional, Morillas, Rosa M, additional, Garcovich, Matteo, additional, García-Retortillo, Montserrat, additional, Martinez, Javier, additional, Cales, Paul, additional, D’Amico, Mario, additional, Dollinger, Matthias, additional, Garcia-Guix, Maria, additional, Ballerga, Esteban Gonzalez, additional, Tsochatzis, Emmanuel, additional, Cirera, Isabel, additional, Albillos, Agustin, additional, Roquin, Guillame, additional, Pasta, Linda, additional, Colomo, Alan, additional, Hidalgo, Nuria Cañete, additional, Boursier, Jerome, additional, Dallio, Marcello, additional, Gasbarrini, Antonio, additional, Angelo, Iacobellis, additional, Gobbo, Giulia, additional, Merli, Manuela, additional, Federico, Alessandro, additional, Svegliati-Baroni, Gianluca, additional, Pozzoni, Pietro, additional, Addario, Luigi, additional, Chessa, Luchino, additional, Ridola, Lorenzo, additional, and Burroughs, Andrew, additional
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- 2023
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45. Burden of non-alcoholic fatty liver disease and usefulness of non-invasive tests to identify advanced liver disease in patients with type 2 diabetes mellitus: interim analysis of an Italian prospective multicentre study
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Caviglia, Gian Paolo, primary, Armandi, Angelo, additional, D’Ambrosio, Roberta, additional, Lampertico, Pietro, additional, Bianco, Cristiana, additional, Valenti, Luca, additional, Ciccioli, Carlo, additional, Pennisi, Grazia, additional, Petta, Salvatore, additional, Brodosi, Lucia, additional, Petroni, Maria Letizia, additional, Marchignoli, Francesca, additional, Pironi, Loris, additional, Sagripanti, Alessandra, additional, Argenziano, Maria Eva, additional, Svegliati-Baroni, Gianluca, additional, and Bugianesi, Elisabetta, additional
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- 2023
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46. Glutathione S-transferase P nuclear distribution and Nrf2/Keap1 interacting properties mark the GSH-dependent drug resistance phenotype of hepatocellular carcinoma
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Bartolini, Desirée, primary, Stabile, Anna Maria, additional, Gurrato, Fabio, additional, Lioci, Gessica, additional, Migni, Anna, additional, Svegliati-Baroni, Gianluca, additional, Sidoni, Angelo, additional, Rende, Mario, additional, and Galli, Francesco, additional
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- 2023
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47. Corrigendum to ‘Non-alcoholic fatty liver disease in adults 2021: A clinical practice guideline of the Italian Association for the Study of the Liver (AISF), the Italian Society of Diabetology (SID) and the Italian Society of Obesity (SIO)’ Nutrition, Metabolism and Cardiovascular diseases volume 32 issue 1 (2022) 1-16
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Marchesini, Giulio, primary, Bugianesi, Elisabetta, additional, Burra, Patrizia, additional, Marra, Fabio, additional, Miele, Luca, additional, Alisi, Anna, additional, Vajro, Piero, additional, Masarone, Mario, additional, Petta, Salvatore, additional, Persico, Marcello, additional, Svegliati-Baroni, Gianluca, additional, Valenti, Luca, additional, Federici, Massimo, additional, Purrello, Francesco, additional, Sasso, Ferdinando Carlo, additional, Targher, Giovanni, additional, Busetto, Luca, additional, Petroni, Maria Letizia, additional, Santini, Ferruccio, additional, Cammà, Calogero, additional, and Colli, Agostino, additional
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- 2023
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48. Oesophageal varices predict complications in compensated advanced non-alcoholic fatty liver disease
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Ministero dell'Istruzione e del Merito, Fonds de Recherche du Québec, Pennisi, Grazia, Enea, Marco, Viganò, Mauro, Schepis, Filippo, Ledinghen, Victor de, Berzigotti, Annalisa, Wai-Sun Wong, Vincent, Fracanzani, Anna Ludovica, Sebastiani, Giada, Lara-Romero, Carmen, Bugianesi, Elisabetta, Svegliati-Baroni, Gianluca, Marra, Fabio, Aghemo, Alessio, Valenti, Luca, Calvaruso, Vincenza, Colecchia, Antonio, Di Maria, Gabriele, La Mantia, Claudia, Lin, Huapeng, Mendoza, Yuly, Pugliese, Nicola, Ravaioli, Federico, Romero-Gómez, Manuel, Saltini, Dario, Craxi, Antonio, Di Marco, Vito, Cammà, Calogero, Petta, Salvatore, Ministero dell'Istruzione e del Merito, Fonds de Recherche du Québec, Pennisi, Grazia, Enea, Marco, Viganò, Mauro, Schepis, Filippo, Ledinghen, Victor de, Berzigotti, Annalisa, Wai-Sun Wong, Vincent, Fracanzani, Anna Ludovica, Sebastiani, Giada, Lara-Romero, Carmen, Bugianesi, Elisabetta, Svegliati-Baroni, Gianluca, Marra, Fabio, Aghemo, Alessio, Valenti, Luca, Calvaruso, Vincenza, Colecchia, Antonio, Di Maria, Gabriele, La Mantia, Claudia, Lin, Huapeng, Mendoza, Yuly, Pugliese, Nicola, Ravaioli, Federico, Romero-Gómez, Manuel, Saltini, Dario, Craxi, Antonio, Di Marco, Vito, Cammà, Calogero, and Petta, Salvatore
- Abstract
[Background & Aims] We aimed to evaluate the impact of oesophageal varices (OV) and their evolution on the risk of complications of compensated advanced chronic liver disease (cACLD) caused by non-alcoholic fatty liver disease (NAFLD). We also assessed the accuracy of non-invasive scores for predicting the development of complications and for identifying patients at low risk of high-risk OV., [Methods] We performed a retrospective assessment of 629 patients with NAFLD-related cACLD who had baseline and follow-up oesophagogastroduodenoscopy and clinical follow-up to record decompensation, portal vein thrombosis (PVT), and hepatocellular carcinoma., [Results] Small and large OV were observed at baseline in 30 and 15.9% of patients, respectively. The 4-year incidence of OV from absence at baseline, and that of progression from small to large OV were 16.3 and 22.4%, respectively. Diabetes and a ≥5% increase in BMI were associated with OV progression. Multivariate Cox regression revealed that small (hazard ratio [HR] 2.24, 95% CI 1.47–3.41) and large (HR 3.86, 95% CI 2.34–6.39) OV were independently associated with decompensation. When considering OV status and trajectories, small (HR 2.65, 95% CI 1.39–5.05) and large (HR 4.90, 95% CI 2.49–9.63) OV at baseline and/or follow-up were independently associated with decompensation compared with the absence of OV at baseline and/or follow-up. The presence of either small (HR 2.8, 95% CI 1.16–6.74) or large (HR 5.29, 95% CI 1.96–14.2) OV was also independently associated with incident PVT., [Conclusion] In NAFLD-related cACLD, the presence, severity, and evolution of OV stratify the risk of developing decompensation and PVT., [Impact and implications] Portal hypertension is the main driver of liver decompensation in chronic liver diseases, and its non-invasive markers can help risk prediction. The presence, severity, and progression of oesophageal varices stratify the risk of complications of non-alcoholic fatty liver disease. Easily obtainable laboratory values and liver stiffness measurement can identify patients at low risk for whom endoscopy may be withheld, and can also stratify the risk of liver-related complications.
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- 2023
49. Recalibrating survival prediction among patients receiving trans‐arterial chemoembolization for hepatocellular carcinoma
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Cucchetti, Alessandro, Giannini, Edoardo G., Mosconi, Cristina, Plaz Torres, Maria Corina, Pieri, Giulia, Farinati, Fabio, Rapaccini, Gian Ludovico, Di Marco, Maria, Caturelli, Eugenio, Sacco, Rodolfo, Cabibbo, Giuseppe, Campani, Claudia, Mega, Andrea, Guarino, Maria, Gasbarrini, Antonio, Svegliati‐Baroni, Gianluca, Foschi, Francesco Giuseppe, Missale, Gabriele, Masotto, Alberto, Nardone, Gerardo, Raimondo, Giovanni, Vidili, Gianpaolo, Brunetto, Maurizia Rossana, Sansone, Vito, Zoli, Marco, Azzaroli, Francesco, Trevisani, Franco, Biselli, Maurizio, Caraceni, Paolo, Gramenzi, Annagiulia, Rampoldi, Davide, Reggidori, Nicola, Santi, Valentina, Stefanini, Benedetta, Granito, Alessandro, Muratori, Luca, Piscaglia, Fabio, Tovoli, Francesco, Magalotti, Donatella, Dajti, Elton, Marasco, Giovanni, Ravaioli, Federico, Cappelli, Alberta, Golfieri, Rita, Renzulli, Matteo, Pelizzaro, Filippo, Penzo, Barbara, Marina Cela, Ester, Facciorusso, Antonio, Cacciato, Valentina, Casagrande, Edoardo, de Matthaeis, Nicoletta, Allegrini, Gloria, Lauria, Valentina, Ghittoni, Giorgia, Pelecca, Giorgio, Chegai, Fabrizio, Coratella, Fabio, Ortenzi, Mariano, Dell'Isola, Serena, Biasini, Elisabetta, Olivani, Andrea, Inno, Alessandro, Marchetti, Fabiana, Celsa, Ciro, Grova, Mauro, Stornello, Caterina, Busacca, Anita, Cammà, Calogero, Maria Rizzo, Giacomo Emanuele, Franzè, Maria Stella, Saitta, Carlo, Sauchella, Assunta, Napoli, Lucia, Bevilacqua, Vittoria, Berardinelli, Dante, Borghi, Alberto, Gardini, Andrea Casadei, Conti, Fabio, Dall'Aglio, Anna Chiara, Ercolani, Giorgio, Marra, Fabio, Di Bonaventura, Chiara, Gitto, Stefano, Adotti, Valentina, Coccoli, Pietro, Malerba, Antonio, Capasso, Mario, Morisco, Filomena, Oliveri, Filippo, Romagnoli, Veronica, Cucchetti, Alessandro, Giannini, Edoardo G., Mosconi, Cristina, Plaz Torres, Maria Corina, Pieri, Giulia, Farinati, Fabio, Rapaccini, Gian Ludovico, Di Marco, Maria, Caturelli, Eugenio, Sacco, Rodolfo, Cabibbo, Giuseppe, Campani, Claudia, Mega, Andrea, Guarino, Maria, Gasbarrini, Antonio, Svegliati‐Baroni, Gianluca, Foschi, Francesco Giuseppe, Missale, Gabriele, Masotto, Alberto, Nardone, Gerardo, Raimondo, Giovanni, Vidili, Gianpaolo, Brunetto, Maurizia Rossana, Sansone, Vito, Zoli, Marco, Azzaroli, Francesco, Trevisani, Franco, Biselli, Maurizio, Caraceni, Paolo, Gramenzi, Annagiulia, Rampoldi, Davide, Reggidori, Nicola, Santi, Valentina, Stefanini, Benedetta, Granito, Alessandro, Muratori, Luca, Piscaglia, Fabio, Tovoli, Francesco, Magalotti, Donatella, Dajti, Elton, Marasco, Giovanni, Ravaioli, Federico, Cappelli, Alberta, Golfieri, Rita, Renzulli, Matteo, Pelizzaro, Filippo, Penzo, Barbara, Marina Cela, Ester, Facciorusso, Antonio, Cacciato, Valentina, Casagrande, Edoardo, de Matthaeis, Nicoletta, Allegrini, Gloria, Lauria, Valentina, Ghittoni, Giorgia, Pelecca, Giorgio, Chegai, Fabrizio, Coratella, Fabio, Ortenzi, Mariano, Dell'Isola, Serena, Biasini, Elisabetta, Olivani, Andrea, Inno, Alessandro, Marchetti, Fabiana, Celsa, Ciro, Grova, Mauro, Stornello, Caterina, Busacca, Anita, Cammà, Calogero, Maria Rizzo, Giacomo Emanuele, Franzè, Maria Stella, Saitta, Carlo, Sauchella, Assunta, Napoli, Lucia, Bevilacqua, Vittoria, Berardinelli, Dante, Borghi, Alberto, Gardini, Andrea Casadei, Conti, Fabio, Dall'Aglio, Anna Chiara, Ercolani, Giorgio, Marra, Fabio, Di Bonaventura, Chiara, Gitto, Stefano, Adotti, Valentina, Coccoli, Pietro, Malerba, Antonio, Capasso, Mario, Morisco, Filomena, Oliveri, Filippo, and Romagnoli, Veronica
- Subjects
Liver Cancer ,Pre-TACE-Predict model ,medicine.medical_specialty ,business.industry ,Trans-arterial chemoembolization ,Pharmaceutical Science ,hepatocellular carcinoma ,medicine.disease ,Gastroenterology ,Complementary and alternative medicine ,Internal medicine ,Hepatocellular carcinoma ,medicine ,Pharmacology (medical) ,Trans arterial chemoembolization ,business - Abstract
Background & Aims The Pre-TACE-Predict model was devised to assess prognosis of patients treated with trans-arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). However, before entering clinical practice, a model should demonstrate that it performs a useful role. Methods We performed an independent external validation of the Pre-TACE model in a cohort that differs in setting and time period from the one that generated the original model. Data from 826 patients treated with TACE for naïve HCC (2008-2018) were used to assess calibration and discrimination of the Pre-TACE-Predict model. Results The four risk-categories identified by the Pre-TACE-Predict model had gradient monotonicity, with median survivals of 52.0, 36.2, 29.9, and 14.1 months respectively. However, predicted survivals systematically underestimated observed survivals (R2: 0.667). A recalibration was adopted maintaining fixed the prognostic index and modifying the baseline survival function. This resulted in an almost perfect calibration (R2: 0.995) in all the four risk categories. Cox regressions showed that aetiology and macrovascular invasion, included in the Pre-TACE-Predict model, had no prognostic impact in the present study population, and that coefficients for tumour size and multiplicity were overestimated. The c-index was similar to that of the m-HAP-III, but higher than those of HAP, m-HAP-II and the six-and-twelve models. Conclusions The recalibration of Pre-TACE-Predict model improved the estimation of survival probabilities of HCC patients treated with TACE. The highest discriminatory ability of the Pre-TACE-model in comparison to other available models, together with risk stratification and recalibration, makes it the best prognostic tool currently available for these patients.
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- 2021
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50. Recommendations for management and treatment of nonalcoholic steatohepatitis
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Ratziu, Vlad, Ghabril, Marwan, Romero-Gomez, Manuel, and Svegliati-Baroni, Gianluca
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- 2018
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