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Your search keyword '"Swagatam Mookherjee"' showing total 3 results
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3 results on '"Swagatam Mookherjee"'

2. In Vitro Activity of JPC 2067 Alone and in Combination with Sulfamethoxazole against Nocardia Species

Author

Swagatam Mookherjee, Carolyn M. Shoen, and Michael Cynamon

Subjects
Pharmacology, Sulfamethoxazole, biology, Triazines, Nocardia Infections, Nocardia, Microbial Sensitivity Tests, Nocardia species, biology.organism_classification, In vitro, Dihydrofolate reductase inhibitor, Anti-Bacterial Agents, Microbiology, Tetrahydrofolate Dehydrogenase, Infectious Diseases, Susceptibility, medicine, Humans, Drug Therapy, Combination, Pharmacology (medical), medicine.drug
Abstract

JPC 2067 is a novel dihydrotriazine dihydrofolate reductase inhibitor that is being developed as an antimalarial therapeutic. We evaluated the in vitro activity of JPC 2067 alone and in combination with sulfamethoxazole (SMX) against a panel of nocardia isolates. The MIC 50 s and MIC 90 s for JPC 2067, SMX, and the combination were 0.125 μg/ml and 4 μg/ml, 16 μg/ml and 32 μg/ml, and 0.03 μg/ml and 2 μg/ml, respectively. JPC 2067 alone and in combination with SMX should be evaluated further to understand its clinical potential.

Published
2012
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3. A Curious Case of a Reaccumulating Black Colored Pleural Effusion!

Author

Vishal Shah, Nathan Minkoff, Brian Changlai, and Swagatam Mookherjee

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, Pleural effusion, Black colored, Medicine, Cardiology and Cardiovascular Medicine, Critical Care and Intensive Care Medicine, business, medicine.disease, Dermatology
Published
2014
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