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The field of environmental ethics has been built as a response to environmental blindness [...]

L’agriculture manifeste l’intrication constitutive du design des territoires, des plantes cultivées, des nourritures et des vies humaines. L’obscurcissement des liens qui sous-tendent cette intégration a fait disparaître peu à peu la compréhension des dynamismes inhérents aux processus naturels, en particulier ceux qui prennent part à l’édification des plantes et des nourritures. Pour le voir, il est nécessaire d’examiner quel type de rationalité oriente l’esprit du design vers la modernisation agricole et l’agriculture numérique. Cet examen prend son éclairage dans la conception de la connaissance chez Goethe, pour qui le tout ne prend sens qu’à la condition d’intégrer l’idée centrale de métamorphose. Cette conception s’applique à tous les plans d’organisation, et donc à l’esprit même du design. Comme antidote à une désintégration des liens qui unissent, les plantes se révèlent une leçon de métamorphose capable de guider l’innovation au service de territoires animés de vie.

The title compound, C13H16O3 [GE-isoEu; systematic name: 2-({2-methoxy-4-[(E)-1-propen-1-yl]phenoxy}methyl)oxirane], which crystallizes in the triclinic P\overline{1} space group, was synthesized in one step from iso-eugenol, a bio-based phenylpropanoid, with an excess of epichlorohydrin. Colourless prismatic crystals suitable for X-ray diffraction were obtained from a mixture of ethyl acetate and cyclohexane, during purification by column chromatography on silica gel. GE-isoEu, which corresponds to the trans isomer of the monoglycidyl ether of iso-eugenol, is based on a 1,2,4-trisubstituted benzene ring by diglycidyl ether, methoxy and 1-(E)-propenyl groups, respectively. In the crystal, molecules are organized through offset π-stacking interactions. Chemically, GE-isoEu constitutes an intermediate in the synthesis protocol of 2-[3-methoxy-4-(2-oxiranylmethoxy)phenyl]-3-methyloxirane (GEEp-isoEu), a diepoxydized monomer used in the manufacturing of thermosetting resins and intended for the elaboration of bio-composites.

The ocean regulates the exchange, storage of carbon dioxide, plays a key role in global control of Earth climate and life, absorbs most of the heat excess from greenhouse gas emissions and provides a remarkable number of resources for the human being. Most of the geo-hazards occur in oceanic areas. Thus, high-quality systematic observations are necessary tools for improving our understanding, and subsequent assimilation to provide early warning systems. A holistic scientific approach for the understanding of the ocean’s interrelated processes requires coordinated and complementary monitoring and observation programmes. Research Infrastructures (RIs) are large-scale facilities that provide resources and services for the scientific communities to conduct high-level research and foster innovation. RIs benefit from strong governance and multi-annual funding from their member states with operational life spans in decades. RIs promote knowledge, outreach and education to public, private, and policy stakeholders, and they play a key role in enabling and developing research in all scientific domains and currently represent a growing share of coordinated investment in research, and also in providing essential observations to operational services such as Copernicus. They are strategically important for Europe to lead a global movement towards a data-driven, interconnected, open digital twin that brings together different disciplines, clean technologies, public and private sectors and a broad scientific/technological community, as well as education and training. In Europe several marine RIs have been established, which are maintained by national and European Union (EU) resources. The aims of these infrastructures are aligned with the key priorities of the UN Decade of Ocean Science for Sustainable Development; and with the new European Research Area (ERA) Policy Agenda annexed to the Council conclusions on the ERA governance1, which set out 20 concrete actions for 2022-2024 to contribute to the priority areas defined in the EU Pact for R&I2. The purpose of this paper is to demonstrate that the combined expertise and assets of Europe’s marine RIs can form a comprehensive and holistic framework for long-term, sustainable integrated marine observation. Through this integration process the marine RIs can become better and better a significant pillar of the European Ocean Observing System (EOOS). Such a framework must be built as part of interfaces of interaction and promote not only scientific excellence but also innovation at all levels.

The claim that environmental virtue ethics (EVE) is anthropocentric appears inherently aporetic since it implies that either anthropocentrism is virtuous or the whole environmental issue is anthropocentric, thus translating vices into virtues or vice versa. Another interpretation is that both the environment and humanity are thought with a vicious conception of centeredness. Conversely, if centeredness is rightly addressed and humanity and its environment are considered as one and the same issue, the focus on anthropocentrism should also be different. By drawing on Felix Guatttari’s ecosophy, this paper proposes that EVE needs to be based on a philosophical understanding of agriculture. Thus, agriculture is the organic and epistemic matrix of our relation to the environment and not merely a section of an abstract environment nor one economic area among others. The environmental crisis is primarily a crisis of humanity within its agricultural matrix. To be an environmentally virtuous human being, a requirement is to face again the burden of our absolute need for food and for fruitful cooperation between farmers and plants, not only animals. This paper discusses the importance of plant ethics and plant topology to understand the specificities of the agricultural matrix. The emphasis will be placed on plant-centered virtue ethics and reframing anthropocentrism by drawing on transdisciplinary conversation with plant practitioners in the context of a research action project.

Understanding and sustainably managing complex environments such as marine ecosystems benefits from an integrated approach to ensure that information about all relevant components and their interactions at multiple and nested spatiotemporal scales are considered. This information is based on a wide range of ocean observations using different systems and approaches. An integrated approach thus requires effective collaboration between areas of expertise in order to improve coordination at each step of the ocean observing value chain, from the design and deployment of multi-platform observations to their analysis and the delivery of products, sometimes through data assimilation in numerical models. Despite significant advances over the last two decades in more cooperation across the ocean observing activities, this integrated approach has not yet been fully realized. The ocean observing system still suffers from organizational silos due to independent and often disconnected initiatives, the strong and sometimes destructive competition across disciplines and among scientists, and the absence of a well-established overall governance framework. Here, we address the need for enhanced organizational integration among all the actors of ocean observing, focusing on the occidental systems. We advocate for a major evolution in the way we collaborate, calling for transformative scientific, cultural, behavioral, and management changes. This is timely because we now have the scientific and technical capabilities as well as urgent societal and political drivers. The ambition of the United Nations Decade of Ocean Science for Sustainable Development (2021–2030) and the various efforts to grow a sustainable ocean economy and effective ocean protection efforts all require a more integrated approach to ocean observing. After analyzing the barriers that currently prevent this full integration within the occidental systems, we suggest nine approaches for breaking down the silos and promoting better coordination and sharing. These recommendations are related to the organizational framework, the ocean science culture, the system of recognition and rewards, the data management system, the ocean governance structure, and the ocean observing drivers and funding. These reflections are intended to provide food for thought for further dialogue between all parties involved and trigger concrete actions to foster a real transformational change in ocean observing.

In this paper, we outline the need for a coordinated international effort toward the building of an open-access Global Ocean Oxygen Database and ATlas (GO2DAT) complying with the FAIR principles (Findable, Accessible, Interoperable, and Reusable). GO2DAT will combine data from the coastal and open ocean, as measured by the chemical Winkler titration method or by sensors (e.g., optodes, electrodes) from Eulerian and Lagrangian platforms (e.g., ships, moorings, profiling floats, gliders, ships of opportunities, marine mammals, cabled observatories). GO2DAT will further adopt a community-agreed, fully documented metadata format and a consistent quality control (QC) procedure and quality flagging (QF) system. GO2DAT will serve to support the development of advanced data analysis and biogeochemical models for improving our mapping, understanding and forecasting capabilities for ocean O2 changes and deoxygenation trends. It will offer the opportunity to develop quality-controlled data synthesis products with unprecedented spatial (vertical and horizontal) and temporal (sub-seasonal to multi-decadal) resolution. These products will support model assessment, improvement and evaluation as well as the development of climate and ocean health indicators. They will further support the decision-making processes associated with the emerging blue economy, the conservation of marine resources and their associated ecosystem services and the development of management tools required by a diverse community of users (e.g., environmental agencies, aquaculture, and fishing sectors). A better knowledge base of the spatial and temporal variations of marine O2 will improve our understanding of the ocean O2 budget, and allow better quantification of the Earth’s carbon and heat budgets. With the ever-increasing need to protect and sustainably manage ocean services, GO2DAT will allow scientists to fully harness the increasing volumes of O2 data already delivered by the expanding global ocean observing system and enable smooth incorporation of much higher quantities of data from autonomous platforms in the open ocean and coastal areas into comprehensive data products in the years to come. This paper aims at engaging the community (e.g., scientists, data managers, policy makers, service users) toward the development of GO2DAT within the framework of the UN Global Ocean Oxygen Decade (GOOD) program recently endorsed by IOC-UNESCO. A roadmap toward GO2DAT is proposed highlighting the efforts needed (e.g., in terms of human resources).

Argo, the international array of profiling floats, is a major component of the global ocean and climate observing system. In 2010, the NAOS (Novel Argo Observing System) project was selected as part of the French “Investissements d’Avenir” Equipex program. The objectives of NAOS were to consolidate the French contribution to Argo’s core mission (global temperature and salinity measurements down to 2000 m), and also to develop the future generation of French Argo profiling floats and prepare the next phase of the Argo program with an extension to the deep ocean (Deep Argo), biogeochemistry (BGC-Argo) and polar seas. This paper summarizes how NAOS has met its objectives. The project significantly boosted France’s contribution to Argo’s core mission by deploying more than 100 NAOS standard Argo profiling floats. In addition, NAOS deployed new-generation floats as part of three scientific experiments: biogeochemical floats in the Mediterranean Sea, biogeochemical floats in the Arctic Ocean, and deep floats with oxygen sensors in the North Atlantic. The experiment in the Mediterranean Sea, launched in 2012, implemented and maintained a network of BGC-Argo floats at basin scale for the first time. The 32 BGC-Argo floats deployed and about 4000 BGC profiles collected have vastly improved characterization of the biogeochemical and ecosystem dynamics of the Mediterranean. Meanwhile, experiments in the Arctic and in the North Atlantic, starting in 2015 and deploying 20 Arctic BGC floats and 23 deep floats, have provided unique observations on biogeochemical cycles in the Arctic and deep-water masses, as well as ocean circulation variability in the North Atlantic. NAOS has therefore paved the way to the new operational phase of the Argo program in France that includes BGC and Deep Argo extensions. The objectives and characteristics of this new phase of Argo-France are discussed in the conclusion.

In the past two decades, the Argo Program has collected, processed, and distributed over two million vertical profiles of temperature and salinity from the upper two kilometers of the global ocean. A similar number of subsurface velocity observations near 1,000 dbar have also been collected. This paper recounts the history of the global Argo Program, from its aspiration arising out of the World Ocean Circulation Experiment, to the development and implementation of its instrumentation and telecommunication systems, and the various technical problems encountered. We describe the Argo data system and its quality control procedures, and the gradual changes in the vertical resolution and spatial coverage of Argo data from 1999 to 2019. The accuracies of the float data have been assessed by comparison with high-quality shipboard measurements, and are concluded to be 0.002°C for temperature, 2.4 dbar for pressure, and 0.01 PSS-78 for salinity, after delayed-mode adjustments. Finally, the challenges faced by the vision of an expanding Argo Program beyond 2020 are discussed.

L’intelligence des plantes met l’intelligence artificielle au défi de répondre de façon adaptée aux enjeux de la transition écologique et du changement climatique. L’approche éthico-biologique adoptée ici considère la portée d’une redéfinition de la vie végétale entre « dignification » subjective et conditionnement numérique. L’intelligence des plantes suppose qu’on leur reconnaisse une capacité à poursuivre leurs propres fins, et donc une entéléchie. Elle en appelle à notre propre intelligence pour interpréter avec précision la cohérence organisée et orientée des mouvements morphiques de métamorphose. Ce qui ne peut être calculé exige notre participation dans de nouvelles pratiques éthico-esthétiques où la relation avec les plantes représente une forme d’écosophie indispensable au déploiement de l’agro-écologie.

Research Infrastructures (RIs) are large-scale facilities encompassing instruments, resources, data and services used by the scientific community to conduct high-level research in their respective fields. The development and integration of marine environmental RIs as European Research Vessel Operators [ERVO] (2020) is the response of the European Commission (EC) to global marine challenges through research, technological development and innovation. These infrastructures (EMSO ERIC, Euro-Argo ERIC, ICOS-ERIC Marine, LifeWatch ERIC, and EMBRC-ERIC) include specialized vessels, fixed-point monitoring systems, Lagrangian floats, test facilities, genomics observatories, bio-sensing, and Virtual Research Environments (VREs), among others. Marine ecosystems are vital for life on Earth. Global climate change is progressing rapidly, and geo-hazards, such as earthquakes, volcanic eruptions, and tsunamis, cause large losses of human life and have massive worldwide socio-economic impacts. Enhancing our marine environmental monitoring and prediction capabilities will increase our ability to respond adequately to major challenges and efficiently. Collaboration among European marine RIs aligns with and has contributed to the OceanObs’19 Conference statement and the objectives of the UN Decade of Ocean Science for Sustainable Development (2021–2030). This collaboration actively participates and supports concrete actions to increase the quality and quantity of more integrated and sustained observations in the ocean worldwide. From an innovation perspective, the next decade will increasingly count on marine RIs to support the development of new technologies and their validation in the field, increasing market uptake and produce a shift in observing capabilities and strategies.

The diepoxy monomer, C13H16O4 {DGE-Eu; systematic name: 2-[3-methoxy-4-(oxiran-2-ylmethoxy)benzyl]oxirane}, was synthesized from eugenol by a three-step reaction. It consists of a 1,2,4-trisubstituted benzene ring substituted by diglycidyl ether, a methoxy group and a methyloxirane group. The three-membered oxirane rings are inclined to the benzene ring by 61.0 (3) and 27.9 (3)°. The methylene C atom of one of the two terminal epoxide rings is positionally disordered [refined occupancy ratio = 0.69 (1):0.31 (1)]. In the crystal, molecules are linked by C—H...O hydrogen bonds, forming layers parallel to the ab plane. The layers are linked by C—H...π interactions, forming a three-dimensional network.

The Mediterranean community represented in this paper is the result of more than 30 years of EU and nationally funded coordination, which has led to key contributions in science concepts and operational initiatives. Together with the establishment of operational services, the community has coordinated with universities, research centers, research infrastructures and private companies to implement advanced multi-platform and integrated observing and forecasting systems that facilitate the advancement of operational services, scientific achievements and mission-oriented innovation. Thus, the community can respond to societal challenges and stakeholders needs, developing a variety of fit-for-purpose services such as the Copernicus Marine Service. The combination of state-of-the-art observations and forecasting provides new opportunities for downstream services in response to the needs of the heavily populated Mediterranean coastal areas and to climate change. The challenge over the next decade is to sustain ocean observations within the research community, to monitor the variability at small scales, e.g., the mesoscale/submesoscale, to resolve the sub-basin/seasonal and inter-annual variability in the circulation, and thus establish the decadal variability, understand and correct the model-associated biases and to enhance model-data integration and ensemble forecasting for uncertainty estimation. Better knowledge and understanding of the level of Mediterranean variability will enable a subsequent evaluation of the impacts and mitigation of the effect of human activities and climate change on the biodiversity and the ecosystem, which will support environmental assessments and decisions. Further challenges include extending the science-based added-value products into societal relevant downstream services and engaging with communities to build initiatives that will contribute to the 2030 Agenda and more specifically to SDG14 and the UN's Decade of Ocean Science for sustainable development, by this contributing to bridge the science-policy gap. The Mediterranean observing and forecasting capacity was built on the basis of community best practices in monitoring and modeling, and can serve as a basis for the development of an integrated global ocean observing system.

The Argo Program has been implemented and sustained for almost two decades, as a global array of about 4000 profiling floats. Argo provides continuous observations of ocean temperature and salinity versus pressure, from the sea surface to 2000 dbar. The successful installation of the Argo array and its innovative data management system arose opportunistically from the combination of great scientific need and technological innovation. Through the data system, Argo provides fundamental physical observations with broad societally-valuable applications, built on the cost-efficient and robust technologies of autonomous profiling floats. Following recent advances in platform and sensor technologies, even greater opportunity exists now than 20 years ago to (i) improve Argo’s global coverage and value beyond the original design, (ii) extend Argo to span the full ocean depth, (iii) add biogeochemical sensors for improved understanding of oceanic cycles of carbon, nutrients, and ecosystems, and (iv) consider experimental sensors that might be included in the future, for example to document the spatial and temporal patterns of ocean mixing. For Core Argo and each of these enhancements, the past, present, and future progression along a path from experimental deployments to regional pilot arrays to global implementation is described. The objective is to create a fully global, top-to-bottom, dynamically complete, and multidisciplinary Argo Program that will integrate seamlessly with satellite and with other in situ elements of the Global Ocean Observing System (Legler et al., 2015). The integrated system will deliver operational reanalysis and forecasting capability, and assessment of the state and variability of the climate system with respect to physical, biogeochemical, and ecosystems parameters. It will enable basic research of unprecedented breadth and magnitude, and a wealth of ocean-education and outreach opportunities.

Well-founded data management systems are of vital importance for ocean observing systems as they ensure that essential data are not only collected but also retained and made accessible for analysis and application by current and future users. Effective data management requires collaboration across activities including observations, metadata and data assembly, quality assurance and control (QA/QC), and data publication that enables local and interoperable discovery and access and secures archiving that guarantees long-term preservation. To achieve this, data should be findable, accessible, interoperable, and reusable (FAIR). Here, we outline how these principles apply to ocean data and illustrate them with a few examples. In recent decades, ocean data managers, in close collaboration with international organizations, have played an active role in the improvement of environmental data standardization, accessibility, and interoperability through different projects, enhancing access to observation data at all stages of the data life cycle and fostering the development of integrated services targeted to research, regulatory, and operational users. As ocean observing systems evolve and an increasing number of autonomous platforms and sensors are deployed, the volume and variety of data increase dramatically. For instance, there are more than 70 data catalogs that contain metadata records for the polar oceans, a situation that makes comprehensive data discovery beyond the capacity of most researchers. To better serve research, operational, and commercial users, more efficient turnaround of quality data in known formats and made available through Web services is necessary. In particular, automation of data workflows will be critical to reduce friction throughout the data value chain. Adhering to the FAIR principles with free, timely, and unrestricted access to ocean observation data is beneficial for the originators, has obvious benefits for users, and is an essential foundation for the development of new services made possible with big data technologies.

The ocean plays a vital role in the global climate system and biosphere, providing crucial resources for humanity including water, food, energy, and raw materials. There is a compelling need to develop an integrated basin-scale ocean observing system to support of ocean management. We articulate a vision for basin-scale ocean observing – A comprehensive All-Atlantic Ocean Observing Systems that benefits all of us living, working and relying on the ocean. Until now, basin-scale ocean observation has been conducted through loosely-aligned arrangements of national and international efforts. The All-Atlantic Ocean Observing System (AtlantOS) is an integrated concept for a forward-looking framework and basin-scale partnership to establish a comprehensive ocean observing system for the Atlantic Ocean as a whole. The system will be sustainable, multi-disciplinary, multi-thematic, efficient, and fit-for-purpose. Platforms, networks, and systems do already exist that operate at various maturity levels. AtlantOS will go beyond the status quo by bringing together the observing communities and countries of the Atlantic basin, providing the opportunity to join and support the system. AtlantOS will build upon the coordinated work of the Global Ocean Observing System (GOOS) and the Group on Earth Observations (GEO), two international bodies that support and coordinate global ocean observing. AtlantOS will complement those efforts and offers a new approach to organizing ocean observing at the basin-scale. AtlantOS will focus not only on the physics but also the biology, ecology and biogeochemistry of the ocean and seafloor and will enhance new partnerships among governments, science, civil society and the private sector.

The oceans play a key role in global issues such as climate change, food security, and human health. Given their vast dimensions and internal complexity, efficient monitoring and predicting of the planet’s ocean must be a collaborative effort of both regional and global scale. A first and foremost requirement for such collaborative ocean observing is the need to follow well-defined and reproducible methods across activities: from strategies for structuring observing systems, sensor deployment and usage, and the generation of data and information products, to ethical and governance aspects when executing ocean observing. To meet the urgent, planet-wide challenges we face, methods across all aspects of ocean observing should be broadly adopted by the ocean community and, where appropriate, should evolve into “Ocean Best Practices.” While many groups have created best practices, they are scattered across the Web or buried in local repositories and many have yet to be digitized. To reduce this fragmentation, we introduce a new open access, permanent, digital repository of best practices documentation (oceanbestpractices.org) that is part of the Ocean Best Practices System (OBPS). The new OBPS provides an opportunity space for the centralized and coordinated improvement of ocean observing methods. The OBPS repository employs user-friendly software to significantly improve discovery and access to methods. The software includes advanced semantic technologies for search capabilities to enhance repository operations. In addition to the repository, the OBPS also includes a peer reviewed journal research topic, a forum for community discussion and a training activity for use of best practices. Together, these components serve to realize a core objective of the OBPS, which is to enable the ocean community to create superior methods for every activity in ocean observing from research to operations to applications that are agreed upon and broadly adopted across communities. Using selected ocean observing examples, we show how the OBPS supports this objective. This paper lays out a future vision of ocean best practices and how OBPS will contribute to improving ocean observing in the decade to come.

Careful definition and illustrative case studies are fundamental work in developing a Blue Economy. As blue research expands with the world increasingly understanding its importance, policy makers and research institutions worldwide concerned with ocean and coastal regions are demanding further and improved analysis of the Blue Economy. Particularly, in terms of the management connotation, data access, monitoring, and product development, countries are making decisions according to their own needs. As a consequence of this lack of consensus, further dialogue including this cases analysis of the blue economy is even more necessary. This paper consists of four chapters: (I) Understanding the concept of Blue Economy, (II) Defining Blue economy theoretical cases, (III) Introducing Blue economy application cases and (IV) Providing an outlook for the future. Chapters (II) and (III) summarizes all the case studies into nine aspects, each aiming to represent different aspects of the blue economy. This paper is a result of knowledge and experience collected from across the global ocean observing community, and is only made possible with encouragement, support and help of all members. Despite the blue economy being a relatively new concept, we have demonstrated our promising exploration in a number of areas. We put forward proposals for the development of the blue economy, including shouldering global responsibilities to protect marine ecological environment, strengthening international communication and sharing development achievements, and promoting the establishment of global blue partnerships. However, there is clearly much room for further development in terms of the scope and depth of our collective understanding and analysis.

The Copernicus Marine Environment Monitoring Service (CMEMS) provides regular and systematic reference information on the physical and biogeochemical ocean and sea-ice state for the global ocean and the European regional seas. CMEMS serves a wide range of users (more than 15,000 users are now registered to the service) and applications. Observations are a fundamental pillar of the CMEMS value-added chain that goes from observation to information and users. Observations are used by CMEMS Thematic Assembly Centres (TACs) to derive high-level data products and by CMEMS Monitoring and Forecasting Centres (MFCs) to validate and constrain their global and regional ocean analysis and forecasting systems. This paper presents an overview of CMEMS, its evolution, and how the value of in situ and satellite observations is increased through the generation of high-level products ready to be used by downstream applications and services. The complementary nature of satellite and in situ observations is highlighted. Long-term perspectives for the development of CMEMS are described and implications for the evolution of the in situ and satellite observing systems are outlined. Results from Observing System Evaluations (OSEs) and Observing System Simulation Experiments (OSSEs) illustrate the high dependencies of CMEMS systems on observations. Finally future CMEMS requirements for both satellite and in situ observations are detailed.

The objective here is to show by a philosophical approach how ecological art contributes to re-qualify environmental times. The basic argument is that one cannot separate the philosophical foundation of problems and the true nature of time, the “Duration” defined by Bergson as a pure intensity underlying all differences in nature. Environmental emergency allows the criticism of time conceived as a spatial dimension, a time that is intrinsically non sustainable. By encouraging a new proximity between art and science, ecological art practices create sensitive tensioning of this criticism in the form of heterochronies – « other » times. The analysis of a number of examples leads to identify three modes of aesthetic expression : i) aesthetics of the ephemeral, cyclic and archaic ; ii) aesthetics of the ongoing, evolving and entangled ; iii) aesthetics of the still, dematerialized and upcoming. The wordings of these different aesthetic modes are identified in a case study, the exhibition-laboratory « The living and its energy » conducted at Inra in Versailles in 2013. This experiment shows the relevance of creating new research situations by forging closer ties between artistic induction, scientific reflection and a philosophy engaged in action. The aim of such practices is to address current mutations of relation to time, their expression in a new aesthetics of Duration and their capacity to sustain an ethics of care by intensity relations.

In only 10 years, the Argo Program has grown from an idea into a functioning global observing system for the subsurface ocean. More than 3000 Argo floats now cover the world’s ocean. With these instruments operating on 10-day cycles, the array provides 9000 temperature/salinity/depth profiles every month that are quickly available via the Global Telecommunications System and the Internet. Argo is recognized as a major advance for oceanography, and a success for Argo’s parent programs, the Global Ocean Data Assimilation Experiment and Climate Variability and Predictability, and for the Global Earth Observation System of Systems. The value of Argo data in ocean data assimilation (ODA) and other applications is being demonstrated, and will grow as the data set is extended in time and as experience in using the data set leads to new applications. The spatial coverage and quality of the Argo data set are improving, with consideration being given to sampling under seasonal ice at higher latitudes, in additional marginal seas, and to greater depths. Argo data products of value in ODA modeling are under development, and Argo data are being tested to confirm their consistency with related satellite and in situ data. Maintenance of the Argo Program for the next decade and longer is needed for a broad range of climate and oceanographic research and for many operational applications in ocean state estimation and prediction.

Data assembly and processing centers are essential elements of the operational oceanography infrastructure. They provide data and products needed by modeling and data assimilation systems; they also provide products directly useable for applications. This paper discusses the role and functions of the data centers for operational oceanography. It describes some of the main data assembly centers (Argo and in situ data, altimetry, sea surface temperature) developed during the Global Ocean Data Assimilation Experiment. An overview of other data centers (wind and fluxes, ocean color, sea ice) is also given. Much progress has been achieved over the past ten years to validate, intercalibrate, and merge altimeter data from multiple satellites. Accuracy and timeliness of products have been improved, and new products have been developed. The same is true for sea surface temperature data through the Global High-Resolution Sea Surface Temperature Pilot Project. A breakthrough in processing, quality control, and assembly for in situ data has also been achieved through the development of the real-time and delayed-mode Argo data system. In situ and remote-sensing data are now systematically and jointly used to calibrate, validate, and monitor over the long term the quality and consistency of the global ocean observing system. Main results are illustrated. There is also a review of the development and use of products that merge in situ and remote-sensing data. Future issues and main prospects are discussed in the conclusion.

The Global Ocean Data Assimilation Experiment (GODAE [http://www.godae.org]) has spanned a decade of rapid technological development. The ever-increasing volume and diversity of oceanographic data produced by in situ instruments, remote-sensing platforms, and computer simulations have driven the development of a number of innovative technologies that are essential for connecting scientists with the data that they need. This paper gives an overview of the technologies that have been developed and applied in the course of GODAE, which now provides users of oceanographic data with the capability to discover, evaluate, visualize, download, and analyze data from all over the world. The key to this capability is the ability to reduce the inherent complexity of oceanographic data by providing a consistent, harmonized view of the various data products. The challenges of data serving have been addressed over the last ten years through the cooperative skills and energies of many individuals.

Increased level of oxidative stress, a major actor of cellular aging, impairs the regenerative capacity of skeletal muscle and leads to the reduction in the number and size of muscle fibers causing sarcopenia. Caveolin 1 is the major component of caveolae, small membrane invaginations involved in signaling and endocytic trafficking. Their role has recently expanded to mechanosensing and to the regulation of oxidative stress-induced pathways. Here, we increased the amount of reactive oxidative species in myoblasts by addition of hydrogen peroxide (H2O2) at non-toxic concentrations. The expression level of caveolin 1 was significantly decreased as early as 10 min after 500 μM H2O2 treatment. This reduction was not observed in the presence of a proteasome inhibitor, suggesting that caveolin 1 was rapidly degraded by the proteasome. In spite of caveolin 1 decrease, caveolae were still able to assemble at the plasma membrane. Their functions however were significantly perturbed by oxidative stress. Endocytosis of a ceramide analog monitored by flow cytometry was significantly diminished after H2O2 treatment, indicating that oxidative stress impaired its selective internalization via caveolae. The contribution of caveolae to the plasma membrane reservoir has been monitored after osmotic cell swelling. H2O2 treatment increased membrane fragility revealing that treated cells were more sensitive to an acute mechanical stress. Altogether, our results indicate that H2O2 decreased caveolin 1 expression and impaired caveolae functions. These data give new insights on age-related deficiencies in skeletal muscle.