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1. Study on the accidental background of the JSNS $$^2$$ 2 experiment

Author: D. H. Lee, S. Ajimura, M. K. Cheoun, J. H. Choi, J. Y. Choi, T. Dodo, J. Goh, K. Haga, M. Harada, S. Hasegawa, T. Hiraiwa, W. Hwang, H. I. Jang, J. S. Jang, H. Jeon, S. Jeon, K. K. Joo, D. E. Jung, S. K. Kang, Y. Kasugai, T. Kawasaki, E. J. Kim, J. Y. Kim, S. B. Kim, W. Kim, H. Kinoshita, T. Konno, I. T. Lim, C. Little, E. Marzec, T. Maruyama, S. Masuda, S. Meigo, S. Monjushiro, D. H. Moon, T. Nakano, M. Niiyama, K. Nishikawa, M. Y. Pac, H. W. Park, J. S. Park, R. G. Park, S. J. M. Peeters, C. Rott, K. Sakai, S. Sakamoto, T. Shima, C. D. Shin, J. Spitz, F. Suekane, Y. Sugaya, K. Suzuya, M. Taira, Y. Yamaguchi, M. Yeh, I. S. Yeo, C. Yoo, and I. Yu
Subjects: Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract JSNS $$^2$$ 2 (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) is an experiment that searches for sterile neutrinos via the observation of $$\bar{\nu }_{\mu } \rightarrow \bar{\nu }_{e}$$ ν ¯ μ → ν ¯ e appearance oscillations using muon decay-at-rest neutrinos. The JSNS $$^2$$ 2 experiment performed data taking from 2021. In this manuscript, a study of the accidental background is presented. The rate of the accidental background is ( $$9.29\pm 0.39) \times 10^{-8}$$ 9.29 ± 0.39 ) × 10 - 8 /spill with 0.75 MW beam power and comparable to the expected number of signal events.
Published: 2024
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2. Measurements of neutrino oscillation parameters from the T2K experiment using $$3.6\times 10^{21}$$ 3.6 × 10 21 protons on target

Author: K. Abe, N. Akhlaq, R. Akutsu, A. Ali, S. Alonso Monsalve, C. Alt, C. Andreopoulos, M. Antonova, S. Aoki, T. Arihara, Y. Asada, Y. Ashida, E. T. Atkin, M. Barbi, G. J. Barker, G. Barr, D. Barrow, M. Batkiewicz-Kwasniak, F. Bench, V. Berardi, L. Berns, S. Bhadra, A. Blanchet, A. Blondel, S. Bolognesi, T. Bonus, S. Bordoni, S. B. Boyd, A. Bravar, C. Bronner, S. Bron, A. Bubak, M. Buizza Avanzini, J. A. Caballero, N. F. Calabria, S. Cao, D. Carabadjac, A. J. Carter, S. L. Cartwright, M. G. Catanesi, A. Cervera, J. Chakrani, D. Cherdack, P. S. Chong, G. Christodoulou, A. Chvirova, M. Cicerchia, J. Coleman, G. Collazuol, L. Cook, A. Cudd, C. Dalmazzone, T. Daret, Yu. I. Davydov, A. De Roeck, G. De Rosa, T. Dealtry, C. C. Delogu, C. Densham, A. Dergacheva, F. Di Lodovico, S. Dolan, D. Douqa, T. A. Doyle, O. Drapier, J. Dumarchez, P. Dunne, K. Dygnarowicz, A. Eguchi, S. Emery-Schrenk, G. Erofeev, A. Ershova, G. Eurin, D. Fedorova, S. Fedotov, M. Feltre, A. J. Finch, G. A. Fiorentini Aguirre, G. Fiorillo, M. D. Fitton, J. M. Franco Patiño, M. Friend, Y. Fujii, Y. Fukuda, K. Fusshoeller, L. Giannessi, C. Giganti, V. Glagolev, M. Gonin, J. González Rosa, E. A. G. Goodman, A. Gorin, M. Grassi, M. Guigue, D. R. Hadley, J. T. Haigh, P. Hamacher-Baumann, D. A. Harris, M. Hartz, T. Hasegawa, S. Hassani, N. C. Hastings, Y. Hayato, D. Henaff, A. Hiramoto, M. Hogan, J. Holeczek, A. Holin, T. Holvey, N. T. Hong Van, T. Honjo, F. Iacob, A. K. Ichikawa, M. Ikeda, T. Ishida, M. Ishitsuka, H. T. Israel, K. Iwamoto, A. Izmaylov, N. Izumi, M. Jakkapu, B. Jamieson, S. J. Jenkins, C. Jesús-Valls, J. J. Jiang, P. Jonsson, S. Joshi, C. K. Jung, P. B. Jurj, M. Kabirnezhad, A. C. Kaboth, T. Kajita, H. Kakuno, J. Kameda, S. P. Kasetti, Y. Kataoka, Y. Katayama, T. Katori, M. Kawaue, E. Kearns, M. Khabibullin, A. Khotjantsev, T. Kikawa, H. Kikutani, S. King, V. Kiseeva, J. Kisiel, T. Kobata, H. Kobayashi, T. Kobayashi, L. Koch, S. Kodama, A. Konaka, L. L. Kormos, Y. Koshio, A. Kostin, T. Koto, K. Kowalik, Y. Kudenko, Y. Kudo, S. Kuribayashi, R. Kurjata, T. Kutter, M. Kuze, M. La Commara, L. Labarga, K. Lachner, J. Lagoda, S. M. Lakshmi, M. Lamers James, M. Lamoureux, A. Langella, J.-F. Laporte, D. Last, N. Latham, M. Laveder, L. Lavitola, M. Lawe, Y. Lee, C. Lin, S.-K. Lin, R. P. Litchfield, S. L. Liu, W. Li, A. Longhin, K. R. Long, A. Lopez Moreno, L. Ludovici, X. Lu, T. Lux, L. N. Machado, L. Magaletti, K. Mahn, M. Malek, M. Mandal, S. Manly, A. D. Marino, L. Marti-Magro, D. G. R. Martin, M. Martini, J. F. Martin, T. Maruyama, T. Matsubara, V. Matveev, C. Mauger, K. Mavrokoridis, E. Mazzucato, N. McCauley, J. McElwee, K. S. McFarland, C. McGrew, J. McKean, A. Mefodiev, G. D. Megias, P. Mehta, L. Mellet, C. Metelko, M. Mezzetto, E. Miller, A. Minamino, O. Mineev, S. Mine, M. Miura, L. Molina Bueno, S. Moriyama, P. Morrison, Th. A. Mueller, D. Munford, L. Munteanu, K. Nagai, Y. Nagai, T. Nakadaira, K. Nakagiri, M. Nakahata, Y. Nakajima, A. Nakamura, H. Nakamura, K. Nakamura, K. D. Nakamura, Y. Nakano, S. Nakayama, T. Nakaya, K. Nakayoshi, C. E. R. Naseby, T. V. Ngoc, V. Q. Nguyen, K. Niewczas, S. Nishimori, Y. Nishimura, K. Nishizaki, T. Nosek, F. Nova, P. Novella, J. C. Nugent, H. M. O’Keeffe, L. O’Sullivan, T. Odagawa, T. Ogawa, R. Okada, W. Okinaga, K. Okumura, T. Okusawa, N. Ospina, R. A. Owen, Y. Oyama, V. Palladino, V. Paolone, M. Pari, J. Parlone, S. Parsa, J. Pasternak, M. Pavin, D. Payne, G. C. Penn, D. Pershey, L. Pickering, C. Pidcott, G. Pintaudi, C. Pistillo, B. Popov, K. Porwit, M. Posiadala-Zezula, Y. S. Prabhu, F. Pupilli, B. Quilain, T. Radermacher, E. Radicioni, B. Radics, M. A. Ramírez, P. N. Ratoff, M. Reh, C. Riccio, E. Rondio, S. Roth, N. Roy, A. Rubbia, A. C. Ruggeri, C. A. Ruggles, A. Rychter, K. Sakashita, F. Sánchez, G. Santucci, C. M. Schloesser, K. Scholberg, M. Scott, Y. Seiya, T. Sekiguchi, H. Sekiya, D. Sgalaberna, A. Shaikhiev, F. Shaker, A. Shaykina, M. Shiozawa, W. Shorrock, A. Shvartsman, N. Skrobova, K. Skwarczynski, D. Smyczek, M. Smy, J. T. Sobczyk, H. Sobel, F. J. P. Soler, Y. Sonoda, A. J. Speers, R. Spina, I. A. Suslov, S. Suvorov, A. Suzuki, S. Y. Suzuki, Y. Suzuki, A. A. Sztuc, M. Tada, S. Tairafune, S. Takayasu, A. Takeda, Y. Takeuchi, K. Takifuji, H. K. Tanaka, Y. Tanihara, M. Tani, A. Teklu, V. V. Tereshchenko, N. Teshima, N. Thamm, L. F. Thompson, W. Toki, C. Touramanis, T. Towstego, K. M. Tsui, T. Tsukamoto, M. Tzanov, Y. Uchida, M. Vagins, D. Vargas, M. Varghese, G. Vasseur, C. Vilela, E. Villa, W. G. S. Vinning, U. Virginet, T. Vladisavljevic, T. Wachala, J. G. Walsh, Y. Wang, L. Wan, D. Wark, M. O. Wascko, A. Weber, R. Wendell, M. J. Wilking, C. Wilkinson, J. R. Wilson, K. Wood, C. Wret, J. Xia, Y.-H. Xu, K. Yamamoto, T. Yamamoto, C. Yanagisawa, G. Yang, T. Yano, K. Yasutome, N. Yershov, U. Yevarouskaya, M. Yokoyama, Y. Yoshimoto, N. Yoshimura, M. Yu, R. Zaki, A. Zalewska, J. Zalipska, K. Zaremba, G. Zarnecki, X. Zhao, T. Zhu, M. Ziembicki, E. D. Zimmerman, M. Zito, S. Zsoldos, and T2K Collaboration
Subjects: Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract The T2K experiment presents new measurements of neutrino oscillation parameters using $$19.7(16.3)\times 10^{20}$$ 19.7 ( 16.3 ) × 10 20 protons on target (POT) in (anti-)neutrino mode at the far detector (FD). Compared to the previous analysis, an additional $$4.7\times 10^{20}$$ 4.7 × 10 20 POT neutrino data was collected at the FD. Significant improvements were made to the analysis methodology, with the near-detector analysis introducing new selections and using more than double the data. Additionally, this is the first T2K oscillation analysis to use NA61/SHINE data on a replica of the T2K target to tune the neutrino flux model, and the neutrino interaction model was improved to include new nuclear effects and calculations. Frequentist and Bayesian analyses are presented, including results on $$\sin ^2\theta _{13}$$ sin 2 θ 13 and the impact of priors on the $$\delta _{\textrm{CP}}$$ δ CP measurement. Both analyses prefer the normal mass ordering and upper octant of $$\sin ^2\theta _{23}$$ sin 2 θ 23 with a nearly maximally CP-violating phase. Assuming the normal ordering and using the constraint on $$\sin ^2\theta _{13}$$ sin 2 θ 13 from reactors, $$\sin ^2\theta _{23}=0.561^{+0.021}_{-0.032}$$ sin 2 θ 23 = 0 . 561 - 0.032 + 0.021 using Feldman–Cousins corrected intervals, and $$\varDelta {}m^2_{32}=2.494_{-0.058}^{+0.041}\times 10^{-3}~\text {eV}^2$$ Δ m 32 2 = 2 . 494 - 0.058 + 0.041 × 10 - 3 eV 2 using constant $$\varDelta \chi ^{2}$$ Δ χ 2 intervals. The CP-violating phase is constrained to $$\delta _{\textrm{CP}}=-1.97_{-0.70}^{+0.97}$$ δ CP = - 1 . 97 - 0.70 + 0.97 using Feldman–Cousins corrected intervals, and $$\delta _{\textrm{CP}}=0,\pi $$ δ CP = 0 , π is excluded at more than 90% confidence level. A Jarlskog invariant of zero is excluded at more than $$2\sigma $$ 2 σ credible level using a flat prior in $$\delta _{\textrm{CP}},$$ δ CP , and just below $$2\sigma $$ 2 σ using a flat prior in $$\sin \delta _{\textrm{CP}}.$$ sin δ CP . When the external constraint on $$\sin ^2\theta _{13}$$ sin 2 θ 13 is removed, $$\sin ^2\theta _{13}=28.0^{+2.8}_{-6.5}\times 10^{-3},$$ sin 2 θ 13 = 28 . 0 - 6.5 + 2.8 × 10 - 3 , in agreement with measurements from reactor experiments. These results are consistent with previous T2K analyses.
Published: 2023
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3. Characterization of the correlated background for a sterile neutrino search using the first dataset of the JSNS $$^2$$ 2 experiment

Author: Y. Hino, S. Ajimura, M. K. Cheoun, J. H. Choi, T. Dodo, H. Furuta, J. Goh, K. Haga, M. Harada, S. Hasegawa, T. Hiraiwa, W. Hwang, H. I. Jang, J. S. Jang, H. Jeon, S. Jeon, K. K. Joo, J. R. Jordan, D. E. Jung, S. K. Kang, Y. Kasugai, T. Kawasaki, E. J. Kim, J. Y. Kim, S. B. Kim, W. Kim, H. Kinoshita, T. Konno, C. Y. Lee, D. H. Lee, S. Lee, I. T. Lim, C. Little, E. Marzec, T. Maruyama, S. Masuda, S. Meigo, S. Monjushiro, D. H. Moon, T. Nakano, M. Niiyama, K. Nishikawa, M. Nomachi, M. Y. Pac, J. S. Park, R. G. Park, S. J. M. Peeters, H. Ray, C. Rott, K. Sakai, S. Sakamoto, T. Shima, C. D. Shin, J. Spitz, F. Suekane, Y. Sugaya, K. Suzuya, M. Taira, R. Ujiie, Y. Yamaguchi, M. Yeh, I. S. Yeo, C. Yoo, and I. Yu
Subjects: Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract JSNS $$^2$$ 2 (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) is an experiment that is searching for sterile neutrinos via the observation of $${\bar{\nu }}_{\mu } \rightarrow {\bar{\nu }}_{e}$$ ν ¯ μ → ν ¯ e appearance oscillations using muon decay-at-rest neutrinos. Before dedicated data taking in the first-half of 2021, we performed a commissioning run for 10 days in June 2020. Using the data obtained in this commissioning run, in this paper, we present an estimate of the correlated background which imitates the $${\bar{\nu }}_{e}$$ ν ¯ e signal in a sterile neutrino search. In addition, in order to demonstrate future prospects of the JSNS $$^2$$ 2 experiment, possible pulse shape discrimination improvements towards reducing cosmic ray induced fast neutron background are described.
Published: 2022
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4. Measurement of the charged-current electron (anti-)neutrino inclusive cross-sections at the T2K off-axis near detector ND280

Author: The T2K collaboration, K. Abe, N. Akhlaq, R. Akutsu, A. Ali, C. Alt, C. Andreopoulos, L. Anthony, M. Antonova, S. Aoki, A. Ariga, T. Arihara, Y. Asada, Y. Ashida, E. T. Atkin, Y. Awataguchi, S. Ban, M. Barbi, G. J. Barker, G. Barr, D. Barrow, C. Barry, M. Batkiewicz-Kwasniak, A. Beloshapkin, F. Bench, V. Berardi, L. Berns, S. Bhadra, S. Bienstock, A. Blondel, S. Bolognesi, T. Bonus, B. Bourguille, S. B. Boyd, D. Brailsford, A. Bravar, D. Bravo Berguño, C. Bronner, S. Bron, A. Bubak, M. Buizza Avanzini, J. Calcutt, T. Campbell, S. Cao, S. L. Cartwright, M. G. Catanesi, A. Cervera, A. Chappell, C. Checchia, D. Cherdack, N. Chikuma, G. Christodoulou, M. Cicerchia, J. Coleman, G. Collazuol, L. Cook, D. Coplowe, A. Cudd, A. Dabrowska, G. De Rosa, T. Dealtry, P. F. Denner, S. R. Dennis, C. Densham, F. Di Lodovico, N. Dokania, S. Dolan, T. A. Doyle, O. Drapier, J. Dumarchez, P. Dunne, A. Eguchi, L. Eklund, S. Emery-Schrenk, A. Ereditato, P. Fernandez, T. Feusels, A. J. Finch, G. A. Fiorentini, G. Fiorillo, C. Francois, M. Friend, Y. Fujii, R. Fujita, D. Fukuda, R. Fukuda, Y. Fukuda, K. Fusshoeller, C. Giganti, T. Golan, M. Gonin, A. Gorin, M. Guigue, D. R. Hadley, J. T. Haigh, P. Hamacher-Baumann, M. Hartz, T. Hasegawa, S. Hassani, N. C. Hastings, T. Hayashino, Y. Hayato, A. Hiramoto, M. Hogan, J. Holeczek, N. T. Hong Van, T. Honjo, F. Iacob, A. K. Ichikawa, M. Ikeda, T. Ishida, T. Ishii, M. Ishitsuka, K. Iwamoto, A. Izmaylov, N. Izumi, M. Jakkapu, B. Jamieson, S. J. Jenkins, C. Jesús-Valls, M. Jiang, S. Johnson, P. Jonsson, C. K. Jung, X. Junjie, P. B. Jurj, M. Kabirnezhad, A. C. Kaboth, T. Kajita, H. Kakuno, J. Kameda, D. Karlen, S. P. Kasetti, Y. Kataoka, Y. Katayama, T. Katori, Y. Kato, E. Kearns, M. Khabibullin, A. Khotjantsev, T. Kikawa, H. Kikutani, H. Kim, S. King, J. Kisiel, A. Knight, A. Knox, T. Kobata, T. Kobayashi, L. Koch, T. Koga, A. Konaka, L. L. Kormos, Y. Koshio, A. Kostin, K. Kowalik, H. Kubo, Y. Kudenko, N. Kukita, S. Kuribayashi, R. Kurjata, T. Kutter, M. Kuze, L. Labarga, J. Lagoda, M. Lamoureux, D. Last, M. Laveder, M. Lawe, M. Licciardi, T. Lindner, R. P. Litchfield, S. L. Liu, X. Li, A. Longhin, L. Ludovici, X. Lu, T. Lux, L. N. Machado, L. Magaletti, K. Mahn, M. Malek, S. Manly, L. Maret, A. D. Marino, L. Marti-Magro, J. F. Martin, T. Maruyama, T. Matsubara, K. Matsushita, V. Matveev, C. Mauger, K. Mavrokoridis, E. Mazzucato, M. McCarthy, N. McCauley, J. McElwee, K. S. McFarland, C. McGrew, A. Mefodiev, C. Metelko, M. Mezzetto, A. Minamino, O. Mineev, S. Mine, M. Miura, L. Molina Bueno, S. Moriyama, J. Morrison, Th. A. Mueller, L. Munteanu, S. Murphy, Y. Nagai, T. Nakadaira, M. Nakahata, Y. Nakajima, A. Nakamura, K. G. Nakamura, K. Nakamura, Y. Nakano, S. Nakayama, T. Nakaya, K. Nakayoshi, C. Nantais, C. E. R. Naseby, T. V. Ngoc, K. Niewczas, K. Nishikawa, Y. Nishimura, E. Noah, T. S. Nonnenmacher, F. Nova, P. Novella, J. Nowak, J. C. Nugent, H. M. O’Keeffe, L. O’Sullivan, T. Odagawa, T. Ogawa, R. Okada, K. Okumura, T. Okusawa, S. M. Oser, R. A. Owen, Y. Oyama, V. Palladino, J. L. Palomino, V. Paolone, M. Pari, W. C. Parker, S. Parsa, J. Pasternak, P. Paudyal, M. Pavin, D. Payne, G. C. Penn, L. Pickering, C. Pidcott, G. Pintaudi, E. S. Pinzon Guerra, C. Pistillo, B. Popov, K. Porwit, M. Posiadala-Zezula, A. Pritchard, B. Quilain, T. Radermacher, E. Radicioni, B. Radics, P. N. Ratoff, E. Reinherz-Aronis, C. Riccio, E. Rondio, S. Roth, A. Rubbia, A. C. Ruggeri, C. A. Ruggles, A. Rychter, K. Sakashita, F. Sánchez, G. Santucci, C. M. Schloesser, K. Scholberg, J. Schwehr, M. Scott, Y. Seiya, T. Sekiguchi, H. Sekiya, D. Sgalaberna, R. Shah, A. Shaikhiev, F. Shaker, A. Shaykina, M. Shiozawa, W. Shorrock, A. Shvartsman, A. Smirnov, M. Smy, J. T. Sobczyk, H. Sobel, F. J. P. Soler, Y. Sonoda, J. Steinmann, S. Suvorov, A. Suzuki, S. Y. Suzuki, Y. Suzuki, A. A. Sztuc, M. Tada, M. Tajima, A. Takeda, Y. Takeuchi, H. K. Tanaka, H. A. Tanaka, S. Tanaka, Y. Tanihara, M. Tani, N. Teshima, L. F. Thompson, W. Toki, C. Touramanis, T. Towstego, K. M. Tsui, T. Tsukamoto, M. Tzanov, Y. Uchida, M. Vagins, S. Valder, Z. Vallari, D. Vargas, G. Vasseur, C. Vilela, W. G. S. Vinning, T. Vladisavljevic, V. V. Volkov, T. Wachala, J. Walker, J. G. Walsh, Y. Wang, D. Wark, M. O. Wascko, A. Weber, R. Wendell, M. J. Wilking, C. Wilkinson, J. R. Wilson, R. J. Wilson, K. Wood, C. Wret, Y. Yamada, K. Yamamoto, C. Yanagisawa, G. Yang, T. Yano, K. Yasutome, S. Yen, N. Yershov, M. Yokoyama, T. Yoshida, M. Yu, A. Zalewska, J. Zalipska, K. Zaremba, G. Zarnecki, M. Ziembicki, E. D. Zimmerman, M. Zito, S. Zsoldos, and A. Zykova
Subjects: Other experiments, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract The electron (anti-)neutrino component of the T2K neutrino beam constitutes the largest background in the measurement of electron (anti-)neutrino appearance at the far detector. The electron neutrino scattering is measured directly with the T2K off-axis near detector, ND280. The selection of the electron (anti-)neutrino events in the plastic scintillator target from both neutrino and anti-neutrino mode beams is discussed in this paper. The flux integrated single differential charged-current inclusive electron (anti-)neutrino cross-sections, dσ/dp and dσ/d cos(θ), and the total cross-sections in a limited phase-space in momentum and scattering angle (p > 300 MeV/c and θ ≤ 45°) are measured using a binned maximum likelihood fit and compared to the neutrino Monte Carlo generator predictions, resulting in good agreement.
Published: 2020
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5. AMPLITUDE VARIATIONS OF THE REFLECTED SIGNAL DURING VERTICAL SOUNDING OF THE IONOSPHERE AT MIDDLE LATITUDES

Author: K.М. Yusupov, J.D. Mathews, T. Maruyama, A.D. Akchurin, M.V. Tolstikov, O.N. Sherstyukov, E.A. Filippova, and A.S. Safiullin
Subjects: ionosonde, ionogram, ionosphere, magnetoionic modes, a-maps, Astrophysics, QB460-466
Abstract: In this paper, we discuss the main types of quasiperiodic variations in amplitudes of a reflected signal during vertical sounding of the ionosphere at middle latitudes. The initial experimental data is vertical sounding ionograms obtained by the Cyclone ionosonde. The ionosonde is located in Kazan (59°, 49°) and in standard mode allows us to receive one ionogram per minute. In the analysis, methods are used to visualize a large flow of ionograms in the form of final summary maps of the state of the ionosphere (A-, H-, As-maps). We give typical examples of quasiperiodic variations in amplitudes of a reflected signal in ionograms and on A-maps for various types of multipath beatings (polarization and due to signal scattering by ionospheric irregularities). Frequency properties of such beatings are used to estimate the difference in virtual reflection heights between modes of different polarizations with high accuracy, which makes it possible to refine the form of the electron density profile of the lower ionosphere. We have detected a phenomenon rare for the mid-latitude Es layer — beatings of two O modes with different virtual reflection heights. We also present features of quasiperiodic variations in amplitudes of a reflected signal on traces of the transient Es layer. We study possible causes of the appearance of such beatings.
Published: 2020
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6. Abnormal Claudin-11 localization and its effects on the blood-testis barrier function during puberty in a cryptorchid rat model

Author: T. Kato, K. Mizuno, H. Nishio, Y. Moritoki, K. Hideyuki, S. Kurokawa, A. Nakane, T. Maruyama, R. Ando, Y. Hayashi, and T. Yasui
Subjects: Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published: 2020
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7. A minimum in the latitude variation of spread-F at March equinox

Author: N. Balan, T. Maruyama, A. K. Patra, and V. L. Narayanan
Subjects: Low-mid latitude spread-F, Minimum and maximum in spread-F, Geography. Anthropology. Recreation, Geology, QE1-996.5
Abstract: Abstract This short paper presents the statistics of spread-F occurrence at four low-mid latitude locations (17.0° N, 21.2° N, 26.5° N and 36.5° N mag. lat.) in Japan longitude sector (~ 135° E) in March to April 2002, 2003 and 2006 (high, medium and low solar activity). The location of a spread-F minimum predicted by theoretical models is identified for the first time. The spread-F minimum occurs at the poleward side of the equatorial ionisation anomaly crest and shifts equatorward from ~ 25° N mag. lat. at high solar activity to below 17° N at low solar activity. The corresponding spread-F maximum occurring on the poleward side of the minimum also shifts equatorward from ~ 35° N (or beyond) at medium solar activity to 20°–25° N at low solar activity. The spread-F occurrence increases with decreasing solar activity at all locations especially at higher latitudes (> ~ 25° N) where there is almost no occurrence at high solar activity.
Published: 2018
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8. Interpretation of deformed ionograms induced by vertical ground motion of seismic Rayleigh waves and infrasound in the thermosphere

Author: T. Maruyama, K. Yusupov, and A. Akchurin
Subjects: Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract: The vertical ground motion of seismic surface waves launches acoustic waves into the atmosphere and induces ionospheric disturbances. Disturbances due to Rayleigh waves near the short-period Airy phase appear as wavy fluctuations in the virtual height of an ionogram and have a multiple-cusp signature (MCS) when the fluctuation amplitude is increased. An extremely developed MCS was observed at Kazan, Russia, after the 2010 M 8.8 Chile earthquake. The ionogram exhibited steep satellite traces for which the virtual heights increased rapidly with frequency starting near the top of cusps and continuing for 0.1–0.2 MHz. This complicated ionogram was analyzed by applying a ray tracing technique to the radio wave propagation in the ionosphere that was perturbed by acoustic waves. Acoustic wavefronts were inclined by the effects of finite Rayleigh wave velocity and sound speed in the thermosphere. The satellite echo traces were reproduced by oblique returns from the inclined wavefronts, in addition to the nearly vertical returns that are responsible for the main trace.
Published: 2016
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9. Development and application of radar reflectometer using micro to infrared waves

Author: A. Mase, Y. Kogi, D. Kuwahara, Y. Nagayama, N. Ito, T. Maruyama, H. Ikezi, X. Wang, M. Inutake, T. Tokuzawa, J. Kohagura, M. Yoshikawa, S. Shinohara, A. Suzuki, F. Sakai, M. Yamashika, B. J. Tobias, C. Muscatello, X. Ren, M. Chen, C. W. Domier, and N. C. Luhmann
Subjects: Electromagnetic waves, radar reflectometry, imaging, plasma, biomedical measurement, remote sensing, Physics, QC1-999
Abstract: Progress in microwave and millimeter-wave technologies has made possible advanced diagnostics for application to various fields, including radio astronomy, alien substance detection, plasma diagnostics, airborne and space-borne imaging radars called as synthetic aperture radars, and living body measurements. Transmission, reflection, scattering, and radiation processes of electromagnetic waves are utilized as diagnostic principles. The diagnostics are classified as active and passive systems. Specifically, active radar reflectometry has become of importance in various applications due to the possibility of high localization and accessibility of the measurements as well as the non-invasive nature of the systems. In this paper, recent development and application of radar reflectometers are described. The key words are profile reflectometry, fluctuation reflectometry, imaging radar (optics imaging and synthetic aperture imaging), and radio-optics fusion technology in order to improve the spatial resolution.
Published: 2018
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10. Relationships between pre-sunset electrojet strength, pre-reversal enhancement and equatorial spread-F onset

Author: J. Uemoto, T. Maruyama, S. Saito, M. Ishii, and R. Yoshimura
Subjects: Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract: The virtual height of the bottom side F-region (h'F) and equatorial spread-F (ESF) onsets at Chumphon (10.7° N, 99.4° E; 3.3° N magnetic latitude) were compared with the behaviour of equatorial electrojet (EEJ) ground strength at Phuket (8.1° N, 98.3° E; 0.1° N magnetic latitude) during the period from November 2007 to October 2008. Increase in the F-layer height and ESF onsets during the evening hours were well connected with the EEJ ground strength before sunset, namely, both the height increase and ESF onsets were suppressed when the integrated EEJ ground strength for the period from 1 to 2 h prior to sunset was negative. The finding suggests observationally that the pre-sunset E-region dynamo current and/or electric field are related to the F-region dynamics and ESF onsets around sunset.
Published: 2010
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11. Equinoctial asymmetry of a low-latitude ionosphere-thermosphere system and equatorial irregularities: evidence for meridional wind control

Author: T. Maruyama, S. Saito, M. Kawamura, K. Nozaki, J. Krall, and J. D. Huba
Subjects: Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract: Nocturnal ionospheric height variations were analyzed along the meridian of 100° E by using ionosonde data. Two ionosondes were installed near the magnetic conjugate points at low latitudes, and the third station was situated near the magnetic equator. Ionospheric virtual heights were scaled every 15 min and vertical E×B drift velocities were inferred from the equatorial station. By incorporating the inferred equatorial vertical drift velocity, ionospheric bottom heights with the absence of wind were modeled for the two low-latitude conjugate stations, and the deviation in heights from the model outputs was used to infer the transequatorial meridional thermospheric winds. The results obtained for the September and March equinoxes of years 2004 and 2005, respectively, were compared, and a significant difference in the meridional wind was found. An oscillation with a period of approximately 7 h of the meridional wind existed in both the equinoxes, but its amplitude was larger in September as compared to that in March. When the equatorial height reached the maximum level due to the evening enhancement of the zonal electric field, the transequatorial meridional wind velocity reached approximately 10 and 40 m/s for the March and September equinoxes, respectively. This asymmetry of the ionosphere-thermosphere system was found to be associated with the previously reported equinoctial asymmetry of equatorial ionospheric irregularities; the probability for equatorial irregularities to occur is higher in March as compared to that in September at the Indian to Western Pacific longitudes. Numerical simulations of plasma bubble developments were conducted by incorporating the transequatorial neutral wind effect, and the results showed that the growth time (e-folding time) of the bubble was halved when the wind velocity changed from 10 to 40 m/s.
Published: 2009
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12. Low latitude ionosphere-thermosphere dynamics studies with inosonde chain in Southeast Asia

Author: T. Maruyama, M. Kawamura, S. Saito, K. Nozaki, H. Kato, N. Hemmakorn, T. Boonchuk, T. Komolmis, and C. Ha Duyen
Subjects: Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract: An ionosonde network consisting of a meridional chain and an equatorial pair was established in the Southeast Asian area. Three of four ionosondes are along the magnetic meridian of 100° E; two are close to the magnetic conjugate points in Northern Thailand and West Sumatra, Indonesia, and the other is near the magnetic equator in the Malay Peninsula, Thailand. The fourth ionosonde is also near the magnetic equator in Vietnam but separated by about 6.3° towards east from the meridional chain. For a preliminary data analysis, nighttime ionospheric height variations at the three stations of the meridional chain were examined. The results demonstrate that the coordination of the network has a great potential for studying ionosphere/thermosphere dynamics. Through the assistance of model calculations, thermospheric neutral winds were inferred and compared with the HWM93 empirical thermospheric wind model. Higher-order wind variations that are not represented in the empirical model were found.
Published: 2007
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13. Regional reference total electron content model over Japan based on neural network mapping techniques

Author: T. Maruyama
Subjects: Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract: A regional reference model of total electron content (TEC) was constructed using data from the GPS Earth Observation Network (GEONET), which consists of more than 1000 Global Positioning System (GPS) satellite receivers distributed over Japan. The data covered almost one solar activity period from April 1997 to June 2007. First, TECs were determined for 32 grid points, expanding from 27 to 45° N in latitude and from 127 to 145° E in longitude at 15-min intervals. Secondly, the time-latitude variation averaged over three days was determined by using the surface harmonic functional expansion. The coefficients of the expansion were then modeled by using a neural network technique with input parameters of the season (day of the year) and solar activity (F10.7 index and sunspot number). Thus, two-dimensional TEC maps (time vs. latitude) can be obtained for any given set of solar activity and day of the year.
Published: 2007
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14. Equatorial ionospheric disturbance observed through a transequatorial HF propagation experiment

Author: T. Maruyama and M. Kawamura
Subjects: Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract: A transequatorial radio-wave propagation experiment at shortwave frequencies (HF-TEP) was done between Shepparton, Australia, and Oarai, Japan, using the radio broadcasting signals of Radio Australia. The receiving facility at Oarai was capable of direction finding based on the MUSIC (Multiple Signal Classification) algorithm. The results were plotted in azimuth-time diagrams (AT plots). During the daytime, the propagation path was close to the great circle connecting Shepparton and Oarai, thus forming a single line in the AT plots. After sunset, off-great-circle paths, or satellite traces in the AT plot, often appeared abruptly to the west and gradually returned to the great circle direction. However, there were very few signals across the great circle to the east. The off-great-circle propagation was very similar to that previously reported and was attributed to reflection by an ionospheric structure near the equator. From the rate of change in the direction, we estimated the drift velocity of the structure to range mostly from 100 to 300 m/s eastward. Multiple instances of off-great-circle propagation with a quasi-periodicity were often observed and their spatial distance in the east-west direction was within the range of large-scale traveling ionospheric disturbances (LS-TIDs). Off-great-circle propagation events were frequently observed in the equinox seasons. Because there were many morphological similarities, the events were attributed to the onset of equatorial plasma bubbles.
Published: 2006
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15. Eastward traverse of equatorial plasma plumes observed with the Equatorial Atmosphere Radar in Indonesia

Author: S. Fukao, T. Yokoyama, T. Tayama, M. Yamamoto, T. Maruyama, and S. Saito
Subjects: Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract: The zonal structure of radar backscatter plumes associated with Equatorial Spread F (ESF), probably modulated by atmospheric gravity waves, has been investigated with the Equatorial Atmosphere Radar (EAR) in West Sumatra, Indonesia (0.20° S, 100.32° E; dip latitude 10.1° S) and the FM-CW ionospheric sounders on the same magnetic meridian as the EAR. The occurrence locations and zonal distances of the ESF plumes were determined with multi-beam observations with the EAR. The ESF plumes drifted eastward while keeping distances of several hundred to a thousand kilometers. Comparing the occurrence of the plumes and the F-layer uplift measured by the FM-CW sounders, plumes were initiated within the scanned area around sunset only, when the F-layer altitude rapidly increased. Therefore, the PreReversal Enhancement (PRE) is considered as having a zonal variation with the scales mentioned above, and this variation causes day-to-day variability, which has been studied for a long time. Modulation of the underlying E-region conductivity by gravity waves, which causes inhomogeneous sporadic-E layers, for example, is a likely mechanism to determine the scale of the PRE.
Published: 2006
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16. Simultaneous observation of sporadic E with a rapid-run ionosonde and VHF coherent backscatter radar

Author: T. Maruyama, S. Saito, M. Yamamoto, and S. Fukao
Subjects: Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract: During the SEEK 2 rocket campaign, ionograms were recorded every minute at the Yamagawa Radio Observatory at about 90km west of the region monitored by a VHF (very high frequency) coherent backscatter radar. Sporadic E-layer parameters, which include the critical (foEs) and blanketing (fbEs) frequencies, the layer height (h'Es), and the width of the range spread of sporadic E-traces, were compared with RTI (range-time-intensity) plots of VHF quasi-periodic (QP) and continuous coherent backscatter echoes. A close relationship was found between the appearance of QP echoes in the RTI plots and the level of spatial inhomogeneity in sporadic E plasma, signified here by the difference between foEs and fbEs. During QP echo events, foEs increased while fbEs decreased, so that the difference foEs-fbEs was enhanced, indicating the development of strong spatial structuring in electron density within a sporadic E-layer. On the other hand, increases in sporadic E range spreading also correlated with the occurrence of QP echoes but the degree of correlation varied from event to event. Continuous radar echoes were observed in association with low altitude sporadic E-layers, located well below 100 km and at times as low as 90 km. During the continuous echo events, both foEs and fbEs were less variable, and the difference foEs-fbEs was small and not as dynamic as in the QP echoes. On the other hand, the Es-layer spread intensified during continuous echoes, which means that some patchiness or corrugation in those low altitude layers is also necessary for the continuous backscatter echoes to take place.
Published: 2006
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17. Derivation of TEC and estimation of instrumental biases from GEONET in Japan

Author: G. Ma and T. Maruyama
Subjects: Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract: This paper presents a method to derive the ionospheric total electron content (TEC) and to estimate the biases of GPS satellites and dual frequency receivers using the GPS Earth Observation Network (GEONET) in Japan. Based on the consideration that the TEC is uniform in a small area, the method divides the ionosphere over Japan into 32 meshes. The size of each mesh is 2° by 2° in latitude and longitude, respectively. By assuming that the TEC is identical at any point within a given mesh and the biases do not vary within a day, the method arranges unknown TECs and biases with dual GPS data from about 209 receivers in a day unit into a set of equations. Then the TECs and the biases of satellites and receivers were determined by using the least-squares fitting technique. The performance of the method is examined by applying it to geomagnetically quiet days in various seasons, and then comparing the GPS-derived TEC with ionospheric critical frequencies (foF2). It is found that the biases of GPS satellites and most receivers are very stable. The diurnal and seasonal variation in TEC and foF2 shows a high degree of conformity. The method using a highly dense receiver network like GEONET is not always applicable in other areas. Thus, the paper also proposes a simpler and faster method to estimate a single receiver’s bias by using the satellite biases determined from GEONET. The accuracy of the simple method is examined by comparing the receiver biases determined by the two methods. Larger deviation from GEONET derived bias tends to be found in the receivers at lower (Key words. Ionosphere (mid-latitude ionosphere; instruments and techniques) – Radio science (radio-wave propagation)
Published: 2003
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18. Heliospheric current sheet inclinations at Venus and Earth

Author: G. Ma, K. Marubashi, and T. Maruyama
Subjects: Science, Physics, QC1-999, Geophysics. Cosmic physics, QC801-809
Abstract: We investigate the inclinations of heliospheric current sheet at two sites in interplanetary space, which are generated from the same solar source. From the data of solar wind magnetic fields observed at Venus (0.72 AU) and Earth (1 AU) during December 1978-May 1982 including the solar maximum of 1981, 54 pairs of candidate sector boundary crossings are picked out, of which 16 pairs are identified as sector boundaries. Of the remainder, 12 pairs are transient structures both at Venus and Earth, and 14 pairs are sector boundaries at one site and have transient structures at the other site. It implies that transient structures were often ejected from the coronal streamer belt around the solar maximum. For the 16 pairs of selected sector boundaries, we determine their normals by using minimum variance analysis. It is found that most of the normal azimuthal angles are distributed between the radial direction and the direction perpendicular to the spiral direction both at Venus and Earth. The normal elevations tend to be smaller than ~ 45° with respect to the solar equatorial plane, indicating high inclinations of the heliospheric current sheet, in particular at Earth. The larger scatter in the azimuth and elevation of normals at Venus than at Earth suggests stronger effects of the small-scale structures on the current sheet at 0.72 AU than at 1 AU. When the longitude difference between Venus and Earth is small (° longitudinally), similar or the same inclinations are generally observed, especially for the sector boundaries without small-scale structures. This implies that the heliospheric current sheet inclination tends to be maintained during propagation of the solar wind from 0.72 AU to 1 AU. Detailed case studies reveal that the dynamic nature of helmet streamers causes variations of the sector boundary structure.Key words. Interplanetary physics (interplanetary magnetic fields; sources of solar wind)
Published: 1999
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19. Dislocation Density Reduction in MOVPE-Grown (211) CdTe/Si by Post-Growth Patterning and Annealing

Author: B. S. Chaudhari, M. Niraula, Y. Takagi, R. Okumura, K. P. Sharma, and T. Maruyama
Subjects: Materials Chemistry, Electrical and Electronic Engineering, Condensed Matter Physics, Electronic, Optical and Magnetic Materials
Published: 2023
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20. Natural history of severe aortic stenosis in elderly heart failure patients who declined transcatheter aortic valve implantation

Author: M Hieda, S Futami, H Tanaka, S Moriyama, S Masui, M Kisanuki, K Hatakeyama, K Irie, T Yokoyama, M Fukata, T Arita, T Maruyama, H Nomura, and K Akashi
Subjects: Cardiology and Cardiovascular Medicine
Abstract: Background Transcatheter aortic valve implantation (TAVI) is an established minimally invasive treatment for elderly patients with severe aortic stenosis (AS). Although it is a relatively minimally invasive procedure, many elderly patients cannot undergo TAVI due to advanced age, advanced dementia, significantly impaired ADL, or because the patient or family does not wish to undergo TAVI. In general, severe AS patients died 5 years after an angina attack, 3 years after syncope symptoms, and 2 years after heart failure symptoms. However, few studies have investigated the prognosis of elderly patients with severe AS who declined TAVI. Purpose This study aimed to comprehend the natural history of elderly severe AS patients who declined aortic valve intervention and identify risk factors for death in the TAVI era. Methods We retrospectively reviewed 2,786 echocardiographic data from our hospital between 2017 and 2021. We identified 504 patients with AS in the echocardiography database. The severe AS was defined by the following echocardiography parameters: peak aortic flow velocity ≥4.0 m/s, aortic valve mean gradient ≥40 mmHg, aortic valve area (AVA) Results The mean age was 89±6 years, and 63 (77%) were women. AHA/ACC classification was Stage A/B/C/D: 0%/52.4%/39.0%/8.5%. As event occurrence, we detected 34 (41.5%) all-cause deaths, 41 (50.0%) major adverse cardiovascular events, 32 (39.0%) development of heart failure, 13 (15.9%) chest pain attacks, and 3 (3.7%) syncope. The time from diagnosis of severe AS to all-cause death was 227±273 days, and the 1-, 2-, and 3-year survival rates were 61.5%, 46.2%, and 36.9%, respectively. Of the heart failure-onset population, 16 (50.0%) were found to have severe AS on initial heart failure admission. The incidence of heart failure at 1, 2, and 3 years after diagnosis of severe AS was 60.1%, 56.7%, and 45.4%, respectively. The time from heart failure to death was 107±147 days. Cox proportional hazards analysis adjusted with age, sex, comorbidities revealed that dementia (HR 4.5, P=0.014) and Katz index Conclusions Compared to the comprehension of the natural history of AS patients, the prognosis in severe AS patients who declined TAVI was extremely poor. Although the elderly patients did not have a high rate of angina attacks or syncope symptoms, probably due to their reduced ADL, the results suggest that dementia prevention and maintenance of exercise tolerance are essential since dementia and reduced ADL (Katz Funding Acknowledgement Type of funding sources: Foundation. Main funding source(s): Clinical Research Promotion Foundation Reiwa 2 Michinari Hieda
Published: 2022
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21. Dysfunction of the blood–testis barrier in undescended testes and the role of androgens in the blood–testis barrier composition

Author: T. Kato, K. Mizuno, H. Nishio, D. Matsumoto, H. Kamisawa, S. Kurokawa, A. Nakane, T. Maruyama, T. Yasui, and Y. Hayashi
Subjects: Urology
Published: 2023
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22. WPT Performance Analysis on Antenna Height Dependency between Circuit-Shape Leaky Waveguide and λ/2 Wavelength Dipole Antenna

Author: M. Nakatsugawa, Y. Kanaya, T. Maruyama, M. Omiya, and Y. Tamayama
Published: 2022
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23. Comparison of wind loads on rectangular net house with numerical simulation and wind tunnel tests

Author: T. Maruyama and M. Tamaki
Subjects: Computer simulation, Net (polyhedron), Environmental science, Horticulture, Wind tunnel, Marine engineering
Published: 2021
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24. Importance of Pulsatility in Left Ventricular Assist Device

Author: M. Hieda and T. Maruyama
Subjects: Biomedical Engineering, Biophysics, Orthopedics and Sports Medicine, Biotechnology
Published: 2022
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25. ROTI Keograms based on CMONOC to characterize the ionopsheric irregularities in 2014

Author: Jinghua Li, Guanyi Ma, T. Maruyama, Qingtao Wan, Jiangtao Fan, Jie Zhang, and Xiaolan Wang
Abstract: Ionospheric irregularities have been studied since ~70 years ago. With the development of global navigation satellite system (GNSS), GNSS networks have been used to get the characteristics of the irregularities, including the drift velocity, the structure, and the evolution and so on. In this paper, keograms based on the Crustal Movement Observation Network of China (CMONOC) were used to characterize the irregularities over the area from 85 to 125°E in longitude and 11 to 35°N in latitude in 2014. Keograms were obtained for the rate of TEC index (ROTI) in each 0.5 longitude degrees and 30 minutes universal time pixel. The results showed that the occurrence rate of irregularities was high in the equinox months and December, and lowest in June in 2014. In equinox months the irregularities often appeared after sunset. In March the irregularities usually had long lifetime of ~5-7 hours and ~5 degrees apparent longitude scales. The long lifetime usually was accompanied by obvious eastward drift of ~100m/s and large vROTI. In September the irregularities had weaker ROTI and shorter lifetime than those in March. In June, they appeared ~2-3 hours later than those in equinoxes and drifted westward. And the summer irregularities had weakest ROTI and their latitude was ~30°N, much higher than those in equinoxes. In December, the irregularities had small patches with a longitude scale of ~2 degrees and short lifetime of ~2 hours. Different from the equatorial irregularities in equinox months, the solstice irregularities mainly appeared should be local phenomenon.
Published: 2022
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26. Category Oriented Analysis for Visual Data Mining.

Author: Hisako Shiohara, Yuichi Iizuka, T. Maruyama, and Seiji Isobe
Published: 1999
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27. Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice

Author: Eric D. Spear, H. J. Worman, Yuefan Wang, W. Hsu, W. Wu, C.-S. Lin, Susan Michaelis, K. Shiladardi, T. Maruyama, C. B. Damoci, T. Hsu, J.-Y. Shin, and Kamsi O. Odinammadu
Subjects: congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Longevity, Biology, Mice, Progeria, Internal medicine, medicine, Animals, Loss function, Prenylation, Binding Sites, Multidisciplinary, integumentary system, Farnesyltransferase inhibitor, Membrane Proteins, Metalloendopeptidases, nutritional and metabolic diseases, Lamin Type A, Progerin, medicine.disease, Phenotype, Embryonic stem cell, Endocrinology, Mutation, Nuclear lamina, Lamin
Abstract: Prelamin A is a farnesylated precursor of lamin A, a nuclear lamina protein. Accumulation of the farnesylated prelamin A variant progerin, with an internal deletion including its processing site, causes Hutchinson-Gilford progeria syndrome. Loss of function mutations in ZMPSTE24, which encodes the prelamin A processing enzyme, lead to accumulation of full-length farnesylated prelamin A and cause related progeroid disorders. Some data suggest that prelamin A also accumulates with physiological aging. Zmpste24-/- mice die young, at ~20 weeks. Because ZMPSTE24 has functions in addition to prelamin A processing, we generated a mouse model to examine effects solely due to the presence of permanently farnesylated prelamin A. These mice have an L648R amino acid substitution in prelamin A that blocks ZMPSTE24-catalyzed processing to lamin A. The LmnaL648R/L648R mice express only prelamin and no mature protein. Notably, nearly all survive to 65-70 weeks, with approximately 40% of male and 75% of female LmnaL648R/L648R mice having near-normal lifespans of 90 weeks (almost 2 years). Starting at ~10 weeks of age, LmnaL648R/L648R mice of both sexes have lower body masses and body fat than controls. By ~20-30 weeks of age, they exhibit detectable cranial, mandibular and dental defects similar to those observed in Zmpste24-/- mice, and have decreased vertebral bone density compared to age- and sex-matched controls. Cultured embryonic fibroblasts from LmnaL648R/L648R mice have aberrant nuclear morphology that is reversible by treatment with a protein farnesyltransferase inhibitor. These novel mice provide a robust model to study the effects of farnesylated prelamin A during physiological aging.
Published: 2021
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28. The JSNS2 detector

Author: Shoichi Hasegawa, R. Ujiie, C. Rott, H. Jeon, M. Taira, J. R. Jordan, A. Zohaib, E. Marzec, M. Y. Pac, K. Nishikawa, Chang Dong Shin, W. Kim, M. Niiyama, Masaharu Nomachi, S. Ajimura, Hidetaka Kinoshita, Dong Ho Moon, S. Lee, Tomoyuki Konno, I. S. Yeo, J. W. Choi, Yoshimi Kasugai, Yuji Yamaguchi, S. Masuda, Y. Hino, Kenji Sakai, M. Jang, Shinichi Sakamoto, Sin Kyu Kang, D. H. Lee, Takeo Kawasaki, Tatsushi Shima, Katsuhiro Haga, T. Maruyama, I. T. Lim, Shin-ichiro Meigo, M. Botran, D. E. Jung, Minfang Yeh, J. Spitz, J. S. Park, T. Dodo, T. Nakano, Junghwan Goh, Toshihiko Hiraiwa, Kentaro Suzuya, Intae Yu, I. Stancu, H. Furuta, Jeong-Sik Choi, S. J. M. Peeters, F. Suekane, Gerrit Roellinghoff, Yorihito Sugaya, Masahide Harada, Eunja Kim, H. I. Jang, S. Monjushiro, C. Yoo, J. Y. Kim, H. Ray, S. Jeon, Myung-Ki Cheoun, J. S. Jang, Sang-Bum Kim, and K. K. Joo
Subjects: Physics, Nuclear and High Energy Physics, Sterile neutrino, Muon, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, FOS: Physical sciences, Instrumentation and Detectors (physics.ins-det), High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), Neutrino detector, Inverse beta decay, Neutron, Spallation, High Energy Physics::Experiment, Neutrino, Nuclear Experiment, Instrumentation, Spallation Neutron Source
Abstract: The JSNS^2 (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) experiment aims to search for oscillations involving a sterile neutrino in the eV^2 mass-splitting range. The experiment will search for the appearance of electron antineutrinos oscillated from muon antineutrinos. The electron antineutrinos are detected via the inverse beta decay process using a liquid scintillator detector. A 1MW beam of 3 GeV protons incident on a spallation neutron target produces an intense and pulsed neutrino source from pion, muon, and kaon decay at rest. The JSNS^2 detector is located 24 m away from the neutrino source and began operation from June 2020. The detector contains 17 tonnes of gadolinium (Gd) loaded liquid scintillator (LS) in an acrylic vessel, as a neutrino target. It is surrounded by 31 tonnes of unloaded LS in a stainless steel tank. Optical photons produced in LS are viewed by 120 R7081 Hamamatsu 10-inch Photomultiplier Tubes (PMTs). In this paper, we describe the JSNS^2 detector design, construction, and operation., 41 pages, 29 figures
Published: 2021

29. Renin-angiotensin system inhibitors can be a first choice drug for hypertension in patients treated with vascular endothelial growth factor inhibitors

Author: S Moriyama, M Hieda, H Fukuda, S Kawano, T Yokoyama, M Fukata, H Kusaba, T Maruyama, E Baba, and K Akashi
Subjects: Cardiology and Cardiovascular Medicine
Abstract: Background Vascular endothelial growth factor Signaling Pathway (VSP) inhibitor suppresses tumor growth in solid cancers with disorganized tumor vasculature.1 However, VSP inhibitor often provokes hypertension as an adverse effect.2 The VSP inhibitor-induced hypertension may lead to a dose reduction or discontinuation of the treatment, which cause to poor prognosis. Therefore, it is important to investigate the appropriate anti-hypertensive treatment during cancer therapy. Although renin-angiotensin system (RAS) inhibitor or calcium channel blocker (CCB) is recommended to first-line anti-hypertensive drugs for cancer patients,3 it has not been well-elucidated whether RAS inhibitor or CCB is a beneficial impact for clinical outcome. Purpose The aim of this study is to clarify whether RAS inhibitor or CCB would be an effective drug as the first antihypertensive drug during VSP inhibitor therapy. Method From the LIFE Study database which consisted of 14 municipality-level information from claims data between 2016 and 2020, 1,263 cancer patients treated with VSP inhibitors were retrospectively reviewed. All patients were stratified into two groups according to hypertensive drugs: (1) RAS inhibitors alone (n=512) and (2) CCBs alone (n=751) (Figure 1). The time to treatment failure (TTF) was substituted as an alternative clinical indicator of overall survival. The Kaplan-Meier survival method with the log-rank test was conducted to compare the TTF between the two groups. In addition, Cox proportional hazard model adjusted with baseline clinical characteristics was performed to analyze determinant factors for TTF. Results There were no difference in baseline characteristics including age, sex, primary cancer site, the type of VSP inhibitors, and past medical histories between the two groups, excepted for renal failure. The rate of renal failure was significantly higher in the RAS inhibitor group than in the CCB group (p=0.013). TTF in the patients treated with RAS inhibitors were significantly longer than that with CCB (median TTF [25th–75th percentile]: 183 [61–455] vs. 153 [61–351] days, p=0.020) (Figure 2). In Cox proportional hazard analysis adjusted with age, sex, past medical history, primary cancer lesion, and type of VSP inhibitors, RAS inhibitor was a significantly independent favorable factor to TTF, compared to CCB (Hazard ratio 0.86, 95% confidence interval [0.77–0.97], p=0.011). Conclusion RAS inhibitor is associated with a favorable clinical outcome than CCB, and can be a first choice for treating hypertension during cancer therapy with VSP inhibitors. Funding Acknowledgement Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Japan Society for the Promotion of Science (JSPS) Grants-in-Aid for Scientific Research (KAKENHI) Figure 1. Patient screening and enrollmentFigure 2. Antihypertensive drugs & TTF
Published: 2021
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30. Impact of hypertension on clinical outcome in patients treated with vascular endothelial growth factor inhibitors

Author: S Moriyama, M Hieda, H Fukuda, S Kawano, T Yokoyama, M Fukata, H Kusaba, T Maruyama, E Baba, and K Akashi
Subjects: cardiovascular diseases, Cardiology and Cardiovascular Medicine
Abstract: Background Vascular endothelial growth factor (VEGF) family is overexpressed in the tumor microenvironment and induces tumor angiogenesis.1 VEGF signaling pathway (VSP) inhibitors are essential therapeutic drugs for solid cancer patients.2 However, VSP inhibitors often provoke drug-specific anti-angiogenesis in normal tissues, which was referred to as on-target toxicity.2 Hypertension (HTN) is one of the most frequent adverse events caused by VSP inhibitors. A previous report demonstrated that VSP inhibitor-induced hypertension is a favorable prognostic factor, contrarily.3However, multiple VSP inhibitors are administered in various cancer types, and then the relation between VSP inhibitor-associated hypertension and clinical outcome is still controversial. Purpose The aim of this study is to elucidate the impacts of HTN and the timing of onset on clinical outcome during cancer therapy with VSP inhibitors. Method We reviewed 2,348 patients who were treated with VSP inhibitors from the LIFE Study database, consisting of 14 municipality-level information from claims data between 2016 and 2020. According to the timing of HTN onset mode, the patients were stratified into 3 groups; (1) new-onset HTN group (n=334): de novo development after VSP inhibitor administration, (2) pre-existing HTN group (n=1,363): existing HTN at baseline, including aggravation after VSP inhibitor initiation, and (3) no HTN group (n=651) (Figure 1). The time to treatment failure (TTF) was applied as a surrogate clinical indicator of overall survival. Event-free survival analysis with the log-rank test was conducted for time to first treatment failure amongst the 3 groups. In addition, Cox proportional hazard models adjusted with clinical characteristics were performed to investigate independent factors for TTF. Results In the event-free survival analysis, both the new-onset HTN and the pre-existing HTN were associated with prolongation of TTF, compared to the non-HTN (p Conclusion In patients treated with VSP inhibitors, both new-onset and pre-existing HTN are independent factors for a favorable clinical outcome, especially new-onset HTN after VSP inhibitors administration. Funding Acknowledgement Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Japan Society for the Promotion of Science (JSPS) Grants-in-Aid for Scientific Research (KAKENHI) Figure 1. Patient screening and enrollmentFigure 2. HTN & TTF
Published: 2021
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31. First T2K measurement of transverse kinematic imbalance in the muon-neutrino charged-current single- π+ production channel containing at least one proton

Author: T. Arihara, Y. Hayato, J. R. Wilson, L. Ludovici, S. V. Cao, M. Gonin, T. Honjo, S. Moriyama, S. Roth, D. G. Payne, A. Nakamura, W. C. Parker, L. Molina Bueno, R. Zaki, C. E. R. Naseby, G. D. Megias, S. K. Lin, C. Alt, J. Parlone, M. Tzanov, J. Kisiel, K. Matsushita, M. Zito, Hidekazu Kakuno, G. Yang, N. Izumi, A. K. Ichikawa, K. Niewczas, Patrick Dunne, J. Kameda, A. Eguchi, C. Touramanis, Antonio Ereditato, N. Yershov, C. Giganti, S. Kuribayashi, R. Okada, B. Jamieson, A. Zalewska, C. Jesús-Valls, Kevin Scott McFarland, D. Cherdack, S. Valder, K. Abe, S. Suvorov, R. P. Litchfield, P. Hamacher-Baumann, K. Yasutome, A. Shvartsman, N. Teshima, D. Bravo Berguño, G. Pintaudi, Y. Fujii, C. Mauger, S. Manly, Federico Sanchez, C. McGrew, L. Koch, C. Andreopoulos, Masato Shiozawa, S. R. Dennis, C. M. Schloesser, Xianguo Lu, M. J. Wilking, Gareth J. Barker, A. Beloshapkin, A. Takeda, B. A. Popov, D. Vargas, M. Grassi, T. A. Doyle, E. Radicioni, Vincenzo Berardi, D. Barrow, Etam Noah, F. J. P. Soler, Alexander Finch, J. Chakrani, A. Hiramoto, T. Hasegawa, A. Gorin, J. Dumarchez, K. Fusshoeller, R.P. Kurjata, S. P. Kasetti, T. Ogawa, L. Munteanu, M. Tajima, Yusuke Koshio, A. T. Suzuki, Y. Nagai, C. K. Jung, Alan Cosimo Ruggeri, A. Kostin, André Rubbia, T. Matsubara, T. Vladisavljevic, L. Magaletti, S. Bhadra, L. Cook, F. Iacob, L. Berns, Yuuki Nakano, R. Fukuda, D. L. Wark, Y. Tanihara, G. C. Penn, G. Vasseur, Y. Kataoka, Th. A. Mueller, Thorsten Lux, A. Maurel, F. Di Lodovico, M. Hartz, A. Bubak, C. Pistillo, Kate Scholberg, T. Sekiguchi, Y. Asada, M. Tada, M. Jakkapu, Shigeki Aoki, M. M. Khabibullin, E. A.G. Goodman, E. T. Atkin, R. Akutsu, T. Okusawa, K. Iwamoto, W. Shorrock, Jaroslaw Pasternak, G. Fiorillo, T. Kikawa, C. Vilela, J. Xia, S. Parsa, M. Ishitsuka, Yu. G. Kudenko, N. C. Hastings, H. K. Tanaka, D. A. Harris, K. Nishizaki, Marco Laveder, C. Yanagisawa, Y. Takeuchi, J. P. Coleman, P. B. Jurj, L. Wan, V. Paolone, Oleg Mineev, A. Dergacheva, Y. Nishimura, T. Yano, H. Nakamura, W. G. S. Vinning, C. Riccio, T. Dealtry, T. Nakadaira, S. Dolan, K. Wood, L. Pickering, E. Mazzucato, Y. Oyama, T. Kobayashi, M. Ziembicki, H. Kikutani, Y. Nakajima, C. Densham, A. Cudd, C. C. Delogu, J. C. Nugent, S. King, G. Zarnecki, A. D. Marino, G. De Rosa, J. G. Walsh, J. Lagoda, Yoshihiro Suzuki, M. Buizza Avanzini, R. A. Owen, N. Thamm, T. Maruyama, Samira Hassani, T. V. Ngoc, A. Cervera, K. Yamamoto, M. Hogan, L. Maret, G.D. Barr, K. Nakamura, Yufeng Wang, D. R. Hadley, A. C. Weber, J. A. Nowak, F. Bench, T. Ishida, T. Odagawa, A. Bravar, Ahmed Ali, A. Shaikhiev, P. N. Ratoff, T. Kutter, A. A. Sztuc, M. Batkiewicz-Kwasniak, T. Wachala, K. Zaremba, M. Tani, L. S.M. Lakshmi, L. Mellet, N. Akhlaq, M. Lawe, Jan T. Sobczyk, Lars Eklund, C. Bronner, T. Bonus, T. Kobata, Teppei Katori, M. B. Smy, L. N. Machado, R. Wendell, A. Rychter, M. Posiadala-Zezula, M. Kabirnezhad, C. Wret, K. Mavrokoridis, G. Collazuol, S. B. Boyd, T. Towstego, C. Francois, E. Rondio, P. Jonsson, B. Quilain, N. McCauley, A. Konaka, D. Munford, L. Labarga, J. McElwee, K. Skwarczynski, A. Minamino, Mark Scott, Stephanie Bron, L. O'Sullivan, T. Yoshida, K. Porwit, C. Wilkinson, C. Ruggles, G. Santucci, Y. Awataguchi, Hiroyuki Sekiya, F. Nova, S. L. Liu, A. Blondel, M. Malek, J. Holeczek, Kendall Mahn, A. Izmaylov, T. Radermacher, M. Cicerchia, Lester D.R. Thompson, M. Mezzetto, K. Kowalik, M. Yu, Masashi Yokoyama, M. Vagins, N. T. Hong Van, A. N. Khotjantsev, J. Zalipska, S. Mine, J. Walker, M. Guigue, M. Miura, K. M. Tsui, S. L. Cartwright, Tsuyoshi Nakaya, M. G. Catanesi, D. Coplowe, Roberto Spina, L. Marti-Magro, H. Sobel, T. S. Nonnenmacher, J. J. Jiang, A. Blanchet, M. Lamoureux, S. Zsoldos, V. Palladino, S. Nakayama, Y. Seiya, A. Longhin, M. Friend, A. Shaykina, Michelangelo Pari, Y. H. Xu, M. Pavin, S. J. Jenkins, T. Tsukamoto, Y. Ashida, Y. Fukuda, G. Christodoulou, K. Sakashita, M. Kuze, Masayuki Nakahata, C. Pidcott, Y. Uchida, Y. Yoshimoto, D. Sgalaberna, M. Reh, L. L. Kormos, B. Radics, B. Bourguille, A. Mefodiev, M. Ikeda, K. Nakayoshi, Kimihiro Okumura, S. Bolognesi, Sy Suzuki, M. Antonova, Y. Katayama, S. Emery-Schrenk, D. Douqa, W. Toki, H. M. O'Keeffe, Y. Sonoda, V. Q. Nguyen, M. O. Wascko, E. Kearns, and D. Pershey
Subjects: Physics, Proton, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, Monte Carlo method, T2K experiment, 01 natural sciences, 7. Clean energy, Nuclear physics, Transverse plane, 0103 physical sciences, Muon neutrino, Neutrino, 010306 general physics, Event (particle physics), Charged current
Abstract: This paper reports the first T2K measurement of the transverse kinematic imbalance in the single-$\pi^+$ production channel of neutrino interactions. We measure the differential cross sections in the muon-neutrino charged-current interaction on hydrocarbon with a single $\pi^+$ and at least one proton in the final state, at the ND280 off-axis near detector of the T2K experiment. The extracted cross sections are compared to the predictions from different neutrino-nucleus interaction event generators. Overall, the results show a preference for models which have a more realistic treatment of nuclear medium effects including the initial nuclear state and final-state interactions.
Published: 2021
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32. Measurements of ν̅ μ and ν̅ μ + ν μ charged-current cross-sections without detected pions or protons on water and hydrocarbon at a mean anti-neutrino energy of 0.86 GeV

Author: M. Barbi, T. Vladisavljevic, A. Longhin, A. Shaykina, M. Lawe, Michelangelo Pari, A. Blanchet, Thorsten Lux, Y. Sonoda, L. Molina Bueno, T. Kikawa, S. Parsa, V. Q. Nguyen, H. W. Sobel, M. Gonin, J. Xia, A. T. Suzuki, A. Dergacheva, C. E. R. Naseby, J. F. Martin, N. Kukita, M. Licciardi, T. Feusels, Y. Tanihara, C. Alt, T. Nakadaira, Shuji Tanaka, R. Shah, J. Lagoda, R. J. Wilson, M. Pavin, S. J. Jenkins, J. R. Wilson, D. Fukuda, L. O'Sullivan, Jochen Steinmann, Xianguo Lu, M. R. Vagins, H. Kikutani, J. G. Walsh, A. Bubak, P. Jonsson, R. A. Owen, P. Novella, K. Iwamoto, K. Niewczas, André Rubbia, Jaroslaw Pasternak, Y. Yoshimoto, M. Batkiewicz-Kwasniak, M. Miura, Marco Laveder, A. Zykova, J. P. Coleman, T. Hayashino, Yuto Ashida, A. J. Finch, R. Fukuda, C. Wret, A. Knox, T. Arihara, T. Sekiguchi, R. Akutsu, J. Morrison, N. McCauley, M. Guigue, A. Pritchard, P. B. Jurj, A. A. Sztuc, J. L. Palomino, G. Zarnecki, Patrick Dunne, P. Paudyal, A. Blondel, T. Koga, B. A. Popov, T. Honjo, A. Rychter, P. Hamacher-Baumann, Oleg Mineev, C. Pistillo, M. Jakkapu, M. Buizza Avanzini, B. Jamieson, G. Christodoulou, K. Nakamura, T. A. Doyle, E. Reinherz-Aronis, Keigo Nakamura, Takaaki Kajita, E. Rondio, B. Quilain, C. J. Densham, K. Yasutome, K. Fusshoeller, Hiroyuki Sekiya, S. L. Cartwright, F. Shaker, W. Uno, C. M. Nantais, F. Nova, K. Porwit, P. F. Denner, R. Fujita, Y. Fukuda, Kendall Mahn, A. K. Ichikawa, V. Paolone, Akitaka Ariga, Ko Okumura, G. Pintaudi, S. Moriyama, Kate Scholberg, D. Cherdack, M. Ziembicki, S. Roth, J. Kameda, J. Zalipska, C. Vilela, S. Kuribayashi, E. S. Pinzon Guerra, Th. A. Mueller, B. Radics, M. Ikeda, A. Zalewska, Federico Sanchez, B. Bourguille, Yousuke Kataoka, Z. Vallari, Y. Takeuchi, K. Wood, R.P. Kurjata, L. F. Thompson, S. Valder, T. Ogawa, T. Golan, M. Hartz, E. D. Zimmerman, C. McGrew, Masayuki Nakahata, C. Pidcott, L. Koch, Y. Asada, A. Gorin, G. A. Fiorentini, A. Knight, A. Shvartsman, N. Teshima, C. Checchia, A. Bravar, Vladimir Volkov, Y. Uchida, Shigeki Aoki, Yuichi Oyama, A. Nakamura, S. Suvorov, R. P. Litchfield, Takatomi Yano, Y. Hayato, C. Andreopoulos, R. A. Wendell, S. Bolognesi, H. M. O'Keeffe, J. Holeczek, S. Hassani, G. Fiorillo, T. Radermacher, Thomas B. Campbell, Yuki Fujii, K. Nakayoshi, D. Bravo Berguño, E. Radicioni, T. Kobata, W. H. Toki, Hiromasa Tanaka, V. A. Matveev, M. B. Smy, T. Towstego, L. Maret, P. N. Ratoff, T. Kutter, Koji Yamamoto, M. McCarthy, M. Zito, Hidekazu Kakuno, Pablo Fernandez, M. O. Wascko, S. Mine, G. Yang, E. Mazzucato, K. Kowalik, Laura Gutermuth Anthony, M. Yu, D. L. Wark, F. Di Lodovico, Yutaka Nakajima, Jan Kisiel, T. Bonus, M. Friend, Teppei Katori, Yanbin Wang, M. Tada, D. J. Payne, K. Abe, T. Okusawa, Jungsang Kim, S. Y. Suzuki, N. Izumi, D. Vargas, J. Dumarchez, N. Chikuma, Vincenzo Berardi, D. Barrow, Etam Noah, C. Bronner, Steven C. Johnson, S. Nakayama, F. J. P. Soler, L. L. Kormos, W. Shorrock, Masaki Ishitsuka, Yoshihiro Suzuki, M. Kuze, T. Tsukamoto, K. Skwarczynski, L. Labarga, A. Eguchi, K. Sakashita, S. M. Oser, L. Berns, S. Yen, M. Hogan, T. Kobayashi, N. C. Hastings, M. Antonova, R. Okada, T. Odagawa, Yoshikazu Yamada, A. N. Khotjantsev, Alan Cosimo Ruggeri, J. Schwehr, D. Karlen, T. Yoshida, Y. Seiya, A. Minamino, Hidetoshi Kubo, A. D. Marino, Hyun-Chul Kim, A. Izmaylov, L. Pickering, Y. Nishimura, S. Manly, S. Ban, S. Bienstock, K. M. Tsui, K. S. McFarland, F. Bench, A. C. Weber, Y. Katayama, G. Vasseur, C. Jesús-Valls, C. Ruggles, G. Santucci, O. Drapier, D. A. Harris, S. Emery-Schrenk, H. K. Tanaka, T. Wachala, T. Ishida, S. P. Kasetti, N. Akhlaq, M. M. Khabibullin, S. L. Liu, M. Posiadala-Zezula, M. G. Catanesi, M. Malek, L. Magaletti, C. Giganti, N. Dokania, S. Berkman, Roberto Spina, A. C. Kaboth, A. Cervera, G. Collazuol, Mark Scott, M. Kabirnezhad, K. Mavrokoridis, J. A. Nowak, A. Chappell, Lars Eklund, T. S. Nonnenmacher, C. Barry, S. Murphy, C. Riccio, C. Mauger, T. Dealtry, E. T. Atkin, M. Cicerchia, Alexei Yu. Smirnov, Yuta Kato, K. Nishikawa, M. Lamoureux, L. N. Machado, J. T. Haigh, S. Zsoldos, V. Palladino, S. B. Boyd, L. Marti-Magro, K. Zaremba, Jan T. Sobczyk, Stephanie Bron, Atsushi Takeda, J. McElwee, D. Sgalaberna, Ahmed Ali, C. Francois, Y. Awataguchi, Xiao-yan Li, W. G. S. Vinning, C. Wilkinson, T. V. Ngoc, C. Yanagisawa, Gareth J. Barker, Yuuki Nakano, D. Coplowe, T. Ishii, A. Hiramoto, T. Hasegawa, Takahiko Matsubara, S. V. Cao, C. Touramanis, M. J. Wilking, M. Jiang, Antonio Ereditato, N. Yershov, T. Maruyama, K. Gameil, J. C. Nugent, G.D. Barr, S. King, F. Iacob, M. Mezzetto, D. R. Hadley, Y. Nagai, W. C. Parker, M. Tani, E. Kearns, G. C. Penn, Masashi Yokoyama, M. Tzanov, C. J. Metelko, Yu.A. Kudenko, A. Dabrowska, K. Matsushita, D. Brailsford, N. T. Hong Van, J. Walker, A. Mefodiev, S. Dolan, T. Lindner, A. Cudd, S. R. Dennis, Tsuyoshi Nakaya, C. M. Schloesser, C. K. Jung, Masato Shiozawa, L. Ludovici, A. Kostin, S. Bhadra, L. Cook, A. Beloshapkin, G. De Rosa, J. Calcutt, A. Shaikhiev, A. Konaka, L. Munteanu, M. Tajima, and Yusuke Koshio
Subjects: chemistry.chemical_classification, Physics, Particle physics, Muon, Proton, 010308 nuclear & particles physics, General Physics and Astronomy, 01 natural sciences, Hydrocarbon, Pion, chemistry, 0103 physical sciences, 010306 general physics, Nucleon, Energy (signal processing), Charged current, Bar (unit)
Abstract: We report measurements of the flux-integrated ν̅μ and ν̅μ + νμ charged-current cross-sections on water and hydrocarbon targets using the T2K anti-neutrino beam with a mean beam energy of 0.86 GeV. The signal is defined as the (anti-)neutrino charged-current interaction with one induced $\mu^\pm$ and no detected charged pion or proton. These measurements are performed using a new WAGASCI module recently added to the T2K setup in combination with the INGRID Proton Module. The phase space of muons is restricted to the high-detection efficiency region, $p_{\mu}>400~{\rm MeV}/c$ and $\theta_{\mu}200~{\rm MeV}/c$, $\theta_{\pi}600~{\rm MeV}/c$, $\theta_{\rm p}
Published: 2021
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33. Development of the Electrical Impedance Method for Oil Film Measurement in EHD Contact Area

Author: M. Maeda, K. Nakano, and T. Maruyama
Subjects: Materials science, Oil film, Composite material, Contact area, Electrical impedance
Published: 2021
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34. Conduction gaps after pulmonary vein isolation due to high contact force ablation in patients with atrial fibrillation

Author: K Takai, K Fujita, M Takada, H Kawai, Satoshi Takahashi, Y Nishibori, T Maruyama, F Yoshikawa, and Takanao Mine
Subjects: medicine.medical_specialty, Isolation (health care), business.industry, medicine.medical_treatment, Atrial fibrillation, Ablation, medicine.disease, Pulmonary vein, Contact force, Internal medicine, medicine, Cardiology, In patient, Cardiology and Cardiovascular Medicine, business
Abstract: Background Catheter ablation for atrial fibrillation (AF) with high contact force (CF) has been reported to lead to the gaps after pulmonary vein isolation (PVI), and the appearance of the gaps depends on the site in the left atrium (LA). Purpose The aim of this study is to clarify the relationship between the gaps appearance and high CF. Methods In the clinical study, 74 consecutive patients (39 males, age 71±9, 46 with paroxysmal AF) underwent conventional PVI with a point-by-point radiofrequency (RF) ablation using a CF sensing catheter (TactiCath SETM). RF energy (J), number of RF point, Lesion index (LSI), force-time integral (FTI), average CF (g), and the degree of LA depression with high CF were evaluated. In the experimental study (figure), the relationship between the ablation area and the degree of depression with high CF using bovine left ventricular wall. Results In the clinical study, the gaps were found in 175 of 1182 sites after first path PVI ablation. The CF in the gap sites was higher than without the gap sites in RPV roof, anterior RSPV and anterior RPV carina (18.9±6.8 vs 15.0±5.7g p=0.0262, 26.4±11.6 vs 19.5±6.0g p=0.0029, 22.7±6.4 vs 19.1±5.5g, p=0.0161). Meanwhile, there were no differences in RF energy, number of RF point, LSI, FTI. High CF (≥30g) showed a depression of 3 mm or more in only RPV roof and anterior RPV (figure). In the experimental study, the ablation range narrowed as the indentation deepened with more than 30g CF (r=0.6417, p=0.0625). Conclusion Catheter ablation for AF with high contact force might lead to the gaps in RPV roof and anterior RPV site by the reduction of the ablation area due to depression caused by the pressure. Extension of each contact force Funding Acknowledgement Type of funding source: None
Published: 2020
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35. The JSNS2 data acquisition system

Author: Shoichi Hasegawa, Yorihito Sugaya, Eunhyang Kwon, J. R. Jordan, R. Ujiie, M. Niiyama, K. Nishikawa, T. Maruyama, J. S. Park, T. Hiraiwa, M. Taira, H. Jeon, K. K. Joo, S. Jeon, Takeo Kawasaki, J. Spitz, Myung-Ki Cheoun, M. Jang, I. T. Lim, M. Botran, Masaharu Nomachi, J. S. Jang, Tatsushi Shima, H. I. Jang, Carsten Rott, Y. Hino, D. H. Lee, S. Monjushiro, Tomoyuki Konno, E. Marzec, M. Y. Pac, Jeong-Sik Choi, S. Ajimura, P. Gwak, F. Suekane, Intae Yu, I. Stancu, S. J. M. Peeters, T. Nakano, H. Furuta, Masahide Harada, Eunja Kim, Seyong Kim, J. Y. Kim, J. H. Seo, C. D. Shin, Kentaro Suzuya, Shinichi Sakamoto, A. Zohaib, S. B. Kim, Kenji Sakai, Sin Kyu Kang, W. Kim, S. Meigo, H. Ray, Hyonsan Seo, Dong Ho Moon, D. E. Jung, Minfang Yeh, Y. Kasugai, and T. Dodo
Subjects: Physics, Photomultiplier, 010308 nuclear & particles physics, business.industry, Detector, Scintillator, 01 natural sciences, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Data acquisition, Optics, 0103 physical sciences, Neutron source, Neutrino, Neutrino oscillation, business, Instrumentation, Mathematical Physics, Spallation Neutron Source
Abstract: The JSNS$^{2}$ (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) experiment aims to search for neutrino oscillations over a 24 m short baseline at J-PARC. The JSNS$^{2}$ inner detector is filled with 17 tons of gadolinium(Gd)-loaded liquid scintillator (LS) with an additional 31 tons of unloaded LS in the intermediate $\gamma$-catcher and an optically separated outer veto volumes. A total of 120 10-inch photomultiplier tubes observe the scintillating optical photons and each analog waveform is stored with the flash analog-to-digital converters. We present details of the data acquisition, processing, and data quality monitoring system. We also present two different trigger logics which are developed for the beam and self-trigger.
Published: 2020

36. First measurement of the charged current ν¯μ double differential cross section on a water target without pions in the final state

Author: J. R. Wilson, Jochen Steinmann, T. Koga, D. Cherdack, S. Valder, C. McGrew, Y. Hayato, C. Andreopoulos, A. Longhin, A. Shaykina, T. Vladisavljevic, Yoshikazu Yamada, Thorsten Lux, M. Gonin, L. Molina Bueno, F. Bench, W. G. S. Vinning, E. Kearns, A. T. Suzuki, M. Pavin, S. J. Jenkins, T. V. Ngoc, A. Knox, J. F. Martin, C. Alt, T. Sekiguchi, T. Nakadaira, Hiroyuki Sekiya, F. Nova, T. Tsukamoto, Masashi Yokoyama, Yasunari Suzuki, Keigo Nakamura, R. Fujita, Y. Fukuda, Kendall Mahn, N. T. Hong Van, Hyun-Chul Kim, G. Christodoulou, J. Walker, Y. Takeuchi, Xianguo Lu, A. Mefodiev, K. Niewczas, L. H. V. Anthony, André Rubbia, S. Moriyama, Masayuki Nakahata, C. Pidcott, T. Ishida, Tsuyoshi Nakaya, J. L. Palomino, Y. Uchida, C. K. Jung, A. Cervera, L. Maret, M. Kabirnezhad, T. S. Nonnenmacher, Masato Shiozawa, C. Barry, S. Murphy, L. Ludovici, P. N. Ratoff, T. Kutter, T. Golan, A. Shvartsman, K. Zaremba, Yuki Fujii, S. Bhadra, L. Cook, R. Akutsu, M. Lamoureux, M. Friend, Teppei Katori, Pablo Fernandez, K. Kowalik, N. Chikuma, D. Vargas, C. Pistillo, Atsushi Takeda, J. Dumarchez, J. Schwehr, D. Brailsford, E. Reinherz-Aronis, G. Fiorillo, S. Bolognesi, B. Quilain, V. Palladino, M. M. Khabibullin, Yuichi Oyama, A. Shaikhiev, Alessandro Ruggeri, R.P. Kurjata, O. Drapier, Y. Nakajima, M. McCarthy, S. R. Dennis, S. Suvorov, R. P. Litchfield, C. M. Schloesser, S. Nakayama, J. T. Haigh, F. Di Lodovico, C. Wilkinson, M. Tada, D. J. Payne, Koji Yamamoto, M. Kuze, M. Mezzetto, N. C. Hastings, A. Zykova, K. Sakashita, S. M. Oser, L. Berns, A. Nakamura, L. Pickering, W. C. Parker, D. Coplowe, Yanbin Wang, Y. Nishimura, S. Manly, C. Riccio, K. Abe, Asher Kaboth, Y. Seiya, L. Magaletti, C. Giganti, Jan Kisiel, M. Tzanov, T. Okusawa, T. Kobayashi, J. A. Nowak, C. Yanagisawa, Jungsang Kim, S. Y. Suzuki, A. Chappell, Lars Eklund, Yuta Kato, C. J. Metelko, K. Matsushita, T. Hayashino, R. Fukuda, S. Berkman, M. Zito, Gareth J. Barker, A. Beloshapkin, E. T. Atkin, S. B. Boyd, T. Wachala, Artur F. Izmaylov, G. De Rosa, S. Ban, J. Calcutt, C. Vilela, T. Ishii, N. Dokania, G. A. Fiorentini, A. Konaka, L. Munteanu, Ahmed Ali, W. H. Toki, M. B. Smy, Xiao-yan Li, E. Mazzucato, Yusuke Koshio, F. Shaker, D. Karlen, S. L. Liu, E. Rondio, N. McCauley, C. M. Nantais, J. Morrison, A. Pritchard, K. Porwit, G. Zarnecki, C. Checchia, M. Buizza Avanzini, Vladimir Volkov, Lester D.R. Thompson, B. Jamieson, Shuji Tanaka, J. Holeczek, T. Radermacher, Thomas B. Campbell, K. Nakayoshi, M. Hogan, Yu. Kudenko, A. A. Sztuc, C. Densham, S. Zsoldos, Patrick Dunne, M. Vagins, M. Barbi, A. N. Khotjantsev, P. F. Denner, K. M. Tsui, N. Kukita, M. Licciardi, M. Lawe, H. W. Sobel, T. Feusels, T. Matsubara, K. Iwamoto, M. G. Catanesi, Marco Laveder, J. P. Coleman, A. Gorin, P. Hamacher-Baumann, Takaaki Kajita, K. Yasutome, A. Zalewska, Federico Sanchez, A. Bravar, Vincenzo Berardi, F. J. P. Soler, S. Bienstock, G. Vasseur, V. Paolone, Z. Vallari, K. Wood, E. D. Zimmerman, R. A. Wendell, T. Maruyama, G.D. Barr, S. V. Cao, M. J. Wilking, C. Touramanis, M. Jiang, Antonio Ereditato, N. Yershov, K. Gameil, A. Hiramoto, T. Hasegawa, A. Minamino, C. Jesús-Valls, G. C. Penn, T. Dealtry, K. Mavrokoridis, A. Dabrowska, M. Malek, A. J. Finch, J. Lagoda, H. A. Tanaka, R. J. Wilson, Akitaka Ariga, B. Bourguille, S. Dolan, T. Lindner, Shigeki Aoki, A. Cudd, M. Guigue, V. Matveev, J. C. Nugent, S. King, Y. Awataguchi, P. Paudyal, B. Radics, Alexei Yu. Smirnov, Hidekazu Kakuno, S. Mine, G. Yang, A. K. Ichikawa, K. Nishikawa, S. L. Cartwright, F. Iacob, Jan T. Sobczyk, M. Ziembicki, M. Ikeda, Kimihiro Okumura, S. Roth, J. Kameda, K. Nakamura, J. Zalipska, Hidetoshi Kubo, D. R. Hadley, C. Francois, A. C. Weber, Y. Nagai, Yousuke Kataoka, E. S. Pinzon Guerra, Th. A. Mueller, D. Fukuda, O. V. Mineev, M. Posiadala-Zezula, A. Knight, R. Shah, G. Collazuol, Mark Scott, J. G. Walsh, L. O'Sullivan, R. A. Owen, P. Novella, M. Batkiewicz-Kwasniak, H. M. O'Keeffe, M. Miura, C. Wret, L. Koch, B. A. Popov, L. L. Kormos, Masaki Ishitsuka, M. O. Wascko, M. Yu, C. Bronner, Kate Scholberg, T. Yoshida, Steven C. Johnson, S. Yen, K. S. McFarland, M. Antonova, M. Hartz, H. K. Tanaka, S. Emery-Schrenk, Yuto Ashida, D. Sgalaberna, A. Blondel, A. Rychter, W. Uno, E. Radicioni, D. L. Wark, W. Shorrock, T. Yano, A. D. Marino, Y. Sonoda, P. Jonsson, and L. Labarga
Subjects: Physics, Scattering cross-section, 010308 nuclear & particles physics, 0103 physical sciences, media_common.cataloged_instance, Library science, Christian ministry, Early career, European union, 010306 general physics, 01 natural sciences, media_common
Abstract: We thank the J-PARC staff for superb accelerator performance. We thank the CERN NA61/SHINE Collaboration for providing valuable particle production data. We acknowledge the support of MEXT, Japan; NSERC (Grant No. SAPPJ-2014-00031), the NRC and CFI, Canada; the CEA and CNRS/IN2P3, France; the DFG, Germany; the INFN, Italy; the National Science Centre and Ministry of Science and Higher Education, Poland; the RSF (Grant No. 19-12-00325) and the Ministry of Science and Higher Education, Russia; MINECO and ERDF funds, Spain; the SNSF and SERI, Switzerland; the STFC, UK; and the DOE, USA. We also thank CERN for the UA1/NOMAD magnet, DESY for the HERA-B magnet mover system, NII for SINET4, the WestGrid and SciNet consortia in Compute Canada, and GridPP in the United Kingdom. In addition, participation of individual researchers and institutions has been further supported by funds from the ERC (FP7), “la Caixa” Foundation (ID 100010434, fellowship code LCF/BQ/IN17/11620050), the European Union’s Horizon 2020 Research and Innovation Programme under the Marie Sklodowska- Curie Grants Agreement No. 713673 and No. 754496, and H2020 Grant No. RISE-GA822070-JENNIFER2 2020 and No. RISE-GA872549-SK2HK; the JSPS, Japan; the Royal Society, UK; French ANR Grant No. ANR-19- CE31-0001; and the DOE Early Career programme, USA.
Published: 2020
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37. Slow control and monitoring system at the JSNS$^{2}$

Author: H. Jeon, S. Ajimura, Intae Yu, I. Stancu, H. Furuta, S. J. M. Peeters, Tomoyuki Konno, I. S. Yeo, J. S. Jang, E.J. Kim, Y. Hino, H. I. Jang, F. Suekane, S. Monjushiro, D H Lee, C. Yoo, T. Maruyama, J. S. Park, Yorihito Sugaya, R. Ujiie, Gerrit Roellinghoff, K. Nishikawa, J. Spitz, S. Sakamoto, M. Taira, J. W. Choi, Tatsushi Shima, J. Y. Kim, Shin-ichiro Meigo, S. Jeon, Myung-Ki Cheoun, Shoichi Hasegawa, Takeo Kawasaki, J. R. Jordan, D. E. Jung, M. Botran, J. H. Choi, J Goh, C. D. Shin, Minfang Yeh, K. K. Joo, K. Suzuya, Toshihiko Hiraiwa, I. T. Lim, Y. Kasugai, E. Marzec, T. Dodo, Dong Ho Moon, Masaharu Nomachi, Carsten Rott, Sin Kyu Kang, Masahide Harada, M. Jang, H. Ray, T. Nakano, M. Y. Pac, S. Lee, S. B. Kim, W. Kim, A. Zohaib, M. Niiyama, and Kenji Sakai
Subjects: Physics, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, Control (management), FOS: Physical sciences, General Physics and Astronomy, Control engineering, Monitoring system, High Energy Physics::Experiment, Instrumentation and Detectors (physics.ins-det)
Abstract: The JSNS$^2$ experiment is aimed to search for sterile neutrino oscillations using a neutrino beam from muon decays at rest. The JSNS$^2$ detector contains 17 tons of 0.1\% gadolinium (Gd) loaded liquid scintillator (LS) as a neutrino target. Detector construction was completed in the spring of 2020. A slow control and monitoring system (SCMS) was implemented for reliable control and quick monitoring of the detector operational status and environmental conditions. It issues an alarm if any of the monitored parameters exceed a preset acceptable range. The SCMS monitors the high voltage (HV) of the photomultiplier tubes (PMTs), the LS level in the detector, possible LS overflow and leakage, the temperature and air pressure in the detector, the humidity of the experimental hall, and the LS flow rate during filling and extraction. An initial 10 days of data-taking with a neutrino beam was done following a successful commissioning of the detector and SCMS in June 2020. In this paper, we present a description of the assembly and installation of the SCMS and its performance., 12 pages, 11 figures
Published: 2020

38. Search for η^{'} Bound Nuclei in the ^{12}C(γ,p) Reaction with Simultaneous Detection of Decay Products

Author: N, Tomida, N, Muramatsu, M, Niiyama, J K, Ahn, W C, Chang, J Y, Chen, M L, Chu, S, Daté, T, Gogami, H, Goto, H, Hamano, T, Hashimoto, Q H, He, K, Hicks, T, Hiraiwa, Y, Honda, T, Hotta, H, Ikuno, Y, Inoue, T, Ishikawa, I, Jaegle, J M, Jo, Y, Kasamatsu, H, Katsuragawa, S, Kido, Y, Kon, T, Maruyama, S, Masumoto, Y, Matsumura, M, Miyabe, K, Mizutani, H, Nagahiro, T, Nakamura, T, Nakano, T, Nam, T N T, Ngan, Y, Nozawa, Y, Ohashi, H, Ohnishi, T, Ohta, K, Ozawa, C, Rangacharyulu, S Y, Ryu, Y, Sada, M, Sasagawa, T, Shibukawa, H, Shimizu, R, Shirai, K, Shiraishi, E A, Strokovsky, Y, Sugaya, M, Sumihama, S, Suzuki, S, Tanaka, A, Tokiyasu, Y, Tsuchikawa, T, Ueda, H, Yamazaki, R, Yamazaki, Y, Yanai, T, Yorita, C, Yoshida, and M, Yosoi
Abstract: We measured missing mass spectrum of the ^{12}C(γ,p) reaction for the first time in coincidence with potential decay products from η^{'} bound nuclei. We tagged an (η+p) pair associated with the η^{'}N→ηN process in a nucleus. After applying kinematical selections to reduce backgrounds, no signal events were observed in the bound-state region. An upper limit of the signal cross section in the opening angle cosθ_{lab}^{ηp}-0.9 was obtained to be 2.2 nb/sr at the 90% confidence level. It is compared with theoretical cross sections, whose normalization ambiguity is suppressed by measuring a quasifree η^{'} production rate. Our results indicate a small branching fraction of the η^{'}N→ηN process and/or a shallow η^{'}-nucleus potential.
Published: 2020

39. Measurement of the muon neutrino charged-current single π+ production on hydrocarbon using the T2K off-axis near detector ND280

Author: Rosario Castillo, B. A. Popov, Alexei Yu. Smirnov, K. Nishikawa, C. K. Jung, M. Ikeda, Masato Shiozawa, L. Ludovici, H. Kakuno, Kate Scholberg, L. Zambelli, Jan T. Sobczyk, S. Bhadra, M. Antonova, D. Hansen, T. Feusels, P. Novella, M. M. Khabibullin, J. C. Nugent, O. Drapier, S. King, E. Kearns, W. G. S. Vinning, M. McCarthy, Masashi Yokoyama, W. Shorrock, N. T. Hong Van, J. Walker, T. V. Ngoc, A. Mefodiev, C. Francois, K. Mavrokoridis, D. R. Hadley, T. Ishida, Tsuyoshi Nakaya, A. D. Marino, A. Hiramoto, T. Hasegawa, S. Tobayama, T. Lou, M. Lawe, J. Harada, H. W. Sobel, J. T. Haigh, Ryuji Tamura, F. Iacob, Gareth J. Barker, F. Nova, A. Shaikhiev, R. G. Calland, S. Bordoni, S. Yamasu, J. Holeczek, T. Radermacher, Thomas B. Campbell, K. Nakamura, P. Hamacher-Baumann, J. P. Coleman, K. Nakayoshi, L. Molina Bueno, A. T. Suzuki, F. Gizzarelli, F. Shaker, T. Tomura, B. Quilain, Vincenzo Berardi, A. Zalewska, Y. Nagai, J. F. Martin, N. D. Patel, F. J. P. Soler, Marco Laveder, T. Nakadaira, S. Valder, T. Shirahige, E. Radicioni, M. Ziembicki, J. Zalipska, J. Insler, F. Sanchez, Shin Sasaki, R. M. Berner, Yufeng Wang, K. Sakashita, S. M. Oser, S. Bienstock, J. L. Palomino, G. Vasseur, L. Berns, M. Posiadala-Zezula, T. Inoue, S. Zsoldos, T.S. Nonnenmacher, A. Ali, K. Iwamoto, Y. Nishimura, D. Shaw, W. H. Toki, Y. Takeuchi, A. Blondel, A. Rychter, Y. Kataoka, Akitaka Ariga, Ko Okumura, L. Pickering, G. Fiorillo, M. Hartz, M. Barbi, Alyssa Garcia, B. Bourguille, T. Kajita, K. Zaremba, P. Stowell, S. Mine, K. M. Tsui, Shigeki Aoki, C. Alt, Yutaka Nakajima, D. Karlen, Atsushi Takeda, G. Yang, S. V. Cao, L. Maret, K. Yasutome, Yoshihiro Suzuki, V. Matveev, A. Bravar, S. L. Liu, P. N. Ratoff, Alessandro Ruggeri, N. Kukita, M. Licciardi, W. Uno, M. Lamoureux, T. Thakore, T. Kutter, T. Matsubara, Hidetoshi Kubo, A. C. Weber, C. Touramanis, M. Friend, M. Jiang, Antonio Ereditato, N. Yershov, Y. Petrov, C. Wilkinson, T. Maruyama, S. Ban, T. Wachala, K. Kowalik, Teppei Katori, M. Hogan, G.D. Barr, G. Collazuol, N. Chikuma, Mark Scott, S. Berkman, T. Ishii, N. Dokania, P. P. Koller, A. Minamino, S. Bolognesi, C. Jesús-Valls, N. McCauley, M. Malek, J. Morrison, T. Golan, V. Paolone, T. Yano, Yoshikazu Yamada, Z. J. Liptak, Y. Awataguchi, Z. Vallari, C. W. Walter, Patrick Dunne, A. Shvartsman, W. Y. Ma, H. J. Kim, A. Pritchard, Yuki Fujii, A. N. Khotjantsev, E. D. Zimmerman, S. J. Jenkins, Todd D. Stewart, M. J. Wilking, Pablo Fernandez, D. Vargas, M. A. M. Rayner, G. Zarnecki, P. F. Denner, A. Knox, J. Dumarchez, J. Schwehr, T. Sekiguchi, M. Buizza Avanzini, Hiroyuki Sekiya, R. Fujita, F. Bench, C. Pistillo, B. Jamieson, Y. Fukuda, Kendall Mahn, Keigo Nakamura, D. Coplowe, D. Brailsford, K. Gameil, Y. Sonoda, C. J. Densham, L. Cook, I. Lamont, A. Cervera, C. Nielsen, M. Kabirnezhad, G. C. Penn, T. Hayashino, R. Fukuda, A. Dabrowska, S. R. Dennis, T. Koga, Per Jönsson, C. M. Schloesser, Shuji Tanaka, Davide Sgalaberna, T. Okusawa, R. Akutsu, Y. Seiya, D. Cherdack, M. R. Vagins, S. Y. Suzuki, K. Abe, C. McGrew, S. Dolan, T. Lindner, L. Koch, Y. Hayato, C. Andreopoulos, A. Cudd, A. C. Kaboth, T. Vladisavljevic, J. Y. Kim, E. Mazzucato, Thorsten Lux, Seiko Hirota, M. Gonin, Y. Ashida, W. Oryszczak, K. S. Wood, G. Christodoulou, M. Mezzetto, M. Zito, Y. Nakanishi, S. Moriyama, Yuichi Oyama, S. Suvorov, R. P. Litchfield, Masayuki Nakahata, C. Pidcott, Y. Uchida, M. Tzanov, C. J. Metelko, A. Longhin, A. Shaykina, Giovanni Fiorentini, K. Matsushita, Yu. Kudenko, E. T. Atkin, A. Beloshapkin, R. A. Intonti, G. De Rosa, Koji Yamamoto, M. Pavin, J. Calcutt, Masaki Ishitsuka, A. Konaka, L. Munteanu, Yusuke Koshio, Leïla Haegel, Takahiro Hiraki, O. V. Mineev, James R. Wilson, Yusuke Suda, C. Vilela, R. Shah, E. Rondio, R. A. Owen, A. Gorin, M. Batkiewicz-Kwasniak, M. Miura, C. Wret, C. M. Nantais, K. E. Duffy, H.A. Tanaka, S. Murphy, Xianguo Lu, M. Yu, J. M. Poutissou, C. Bronner, K. Niewczas, M. Guigue, P. Paudyal, J. Walsh, J. P. Lopez, J. Imber, L. H. V. Anthony, André Rubbia, S. L. Cartwright, K. Huang, K. Porwit, S. Manly, Xiao-yan Li, L. L. Kormos, W. Parker, P. Przewlocki, P. Lasorak, S. Martynenko, David A. Wark, J. Lagoda, R. J. Wilson, C. Checchia, Vladimir Volkov, A. Nakamura, Lester D.R. Thompson, R. Tacik, D. Fukuda, C. Riccio, M. G. Catanesi, L. O'Sullivan, T. Yoshida, K. S. McFarland, Jan Kisiel, L. Labarga, T. Kobayashi, H. K. Tanaka, A. Zykova, J. Amey, Alexander Finch, T. Dealtry, A. Missert, B. Radics, P. Martins, F. Di Lodovico, M. Tada, D. J. Payne, M. Kuze, N. C. Hastings, Steven C. Johnson, S. Nakayama, R. A. Wendell, S. Yen, S. Emery-Schrenk, T. Tsukamoto, A. K. Ichikawa, S. Roth, J. Kameda, Y. Azuma, E. S. Pinzon Guerra, Th. A. Mueller, A. Knight, J. Steinmann, H. M. O'Keeffe, T. Ovsyannikova, M. O. Wascko, C. Barry, B. Rossi, C. Yanagisawa, L. Magaletti, C. Giganti, V. Palladino, J. A. Nowak, E. Iwai, A. Chappell, A. A. Sztuc, E. Reinherz-Aronis, E. Scantamburlo, R.P. Kurjata, F. Hosomi, M. B. Smy, Lars Eklund, Yuta Kato, A. Hillairet, L. N. Machado, S. B. Boyd, and Artur F. Izmaylov
Subjects: Physics, Muon, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, 7. Clean energy, 01 natural sciences, Nuclear physics, Cross section (physics), Pion, 0103 physical sciences, High Energy Physics::Experiment, Muon neutrino, Production (computer science), Neutrino, Nuclear Experiment, 010306 general physics, Nucleon, Charged current
Abstract: We report the measurements of single and double differential cross section of muon neutrino charged-current interactions on carbon with a single positively charged pion in the final state at the T2K off-axis near detector using $5.56\times10^{20}$ protons on target. The analysis uses data control samples for the background subtraction and the cross section signal, defined as a single negatively charged muon and a single positively charged pion exiting from the target nucleus, is extracted using an unfolding method. The model dependent cross section, integrated over the T2K off-axis neutrino beam spectrum peaking at $0.6$~GeV, is measured to be $\sigma = (11.76 \pm 0.44 \text{(stat)} \pm 2.39 \text{(syst)}) \times 10^{-40} \text{cm}^2$~$\text{nucleon}^{-1}$. Various differential cross sections are measured, including the first measurement of the Adler angles for single charged pion production in neutrino interactions with heavy nuclei target.
Published: 2020
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40. Performance of PMTs for the JSNS2 experiment

Author: S. B. Kim, F. Suekane, Shoichi Hasegawa, Masahide Harada, Eunja Kim, K. K. Joo, Jeong-Sik Choi, Kenji Sakai, Eunhyang Kwon, Intae Yu, J. Y. Kim, T. Maruyama, I. Stancu, M. Y. Pac, M. Niiyama, M. Taira, Shinichi Sakamoto, S. J. M. Peeters, T. Nakano, A. Zohaib, J. H. Seo, W. Kim, C. D. Shin, Y. Hino, Kentaro Suzuya, P. Gwak, E. Marzec, Seyong Kim, M. Jang, D. E. Jung, Minfang Yeh, H. Jeon, Y. Kasugai, S. Jeon, Myung-Ki Cheoun, T. Dodo, J. S. Jang, I. T. Lim, H. Furuta, Tatsushi Shima, Masaharu Nomachi, T. Hiraiwa, Hyonsan Seo, J. S. Park, S. Ajimura, J. R. Jordan, H. Ray, S. Meigo, R. Ujiie, J. Spitz, Sin Kyu Kang, Tomoyuki Konno, D. H. Lee, Carsten Rott, M. Botran, K. Nishikawa, Dong Ho Moon, Takeo Kawasaki, Yorihito Sugaya, H. I. Jang, and S. Monjushiro
Subjects: Physics, Photomultiplier, Scintillation, Physics - Instrumentation and Detectors, 010308 nuclear & particles physics, business.industry, FOS: Physical sciences, Instrumentation and Detectors (physics.ins-det), Scintillator, 01 natural sciences, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Optics, Neutrino detector, 0103 physical sciences, Neutron source, Neutrino, Neutrino oscillation, business, Instrumentation, Mathematical Physics, Spallation Neutron Source
Abstract: The JSNS$^{2}$ (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) experiment aims to search for neutrino oscillations over a 24\,m short baseline at J-PARC. The JSNS$^{2}$ inner detector is filled with 17 tons of gadolinium-loaded liquid scintillator (LS) and both the intermediate $\gamma$-catcher and the optically separated outer veto are filled with un-loaded LS. Optical photons from scintillation are observed by 120 Photomultiplier Tubes (PMTs). A total of 130 PMTs for the JSNS2 experiment were both donated by other experiments and purchased from Hamamatsu. Donated PMTs were purchased around 10 years ago, therefore JSNS$^{2}$ did pre-calibration of the PMTs including the purchased PMTs. 123 PMTs demonstrated acceptable performance for the JSNS$^{2}$ experiment, and 120 PMTs were installed in the detector.
Published: 2020
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41. Structural displacement compensation of a gigantic manipulator via deep learning

Author: N. Takeda, T. Maruyama, S. Tolsma, M. Edaya, K. Noda, S. Ogawa, and N. Jaklin
Subjects: business.industry, Deep learning, Blanket, Virtual reality, Robot end effector, Displacement (vector), law.invention, Compensation (engineering), law, System integration, Artificial intelligence, Manipulator, business, Simulation
Abstract: Structures of robotic systems that handle extremely heavy loads undergo static displacement. The ITER blanket remote handling system, which handles 4-ton objects, has displacements of up to 100 mm at the end effector. We propose a novel method that combines deep learning with a physics-based virtual reality system to compensate for displacement. Our deep learning model was trained by using data obtained from both the virtual reality system and physical measurement data of end effector positions. By using a prototype of the ITER blanket remote handling system, we experimentally show that our method successfully reduces the displacement at the end effector to a maximum error of 5.7 mm and a median error of 1.2 mm. We conclude that our approach provides an effective contribution to ensuring the feasibility and safety of the remote maintenance procedures that are to be performed within the ITER project.
Published: 2020
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42. Measurement of the charged-current electron (anti-)neutrino inclusive cross-sections at the T2K off-axis near detector ND280

Author: M. Gonin, Lars Eklund, C. Bronner, T. Vladisavljevic, E. Rondio, N. McCauley, C. M. Nantais, Thorsten Lux, K. Porwit, A. Eguchi, C. Touramanis, M. Jiang, Antonio Ereditato, N. Yershov, M. McCarthy, T. Lindner, T. Kikawa, Kevin Scott McFarland, S. Suvorov, R. P. Litchfield, S. Ban, M. Barbi, P. Hamacher-Baumann, L. Molina Bueno, B. Radics, B. Bourguille, A. Mefodiev, Vladimir Volkov, S. R. Johnson, J. Morrison, J. McElwee, C. E. R. Naseby, Lester D.R. Thompson, M. Mezzetto, N. Dokania, S. M. Oser, G. Pintaudi, Y. Ashida, A. Gorin, M. Ikeda, K. Nakayoshi, Kimihiro Okumura, M. J. Wilking, C. Alt, N. Teshima, A. T. Suzuki, Y. Nagai, Y. Fukuda, G. Christodoulou, P. B. Jurj, G. Zarnecki, M. Buizza Avanzini, F. Iacob, L. Berns, T. Towstego, S. Murphy, S. Bolognesi, C. K. Jung, B. Quilain, J. Kameda, T. Okusawa, Alexander N. Smirnov, K. Nakamura, K. Sakashita, M. Kuze, G.D. Barr, K. Niewczas, M. M. Khabibullin, R. Wendell, Y. Tanihara, Th. A. Mueller, N. Kukita, M. Licciardi, T. Feusels, T. Hayashino, R. Fukuda, C. Wilkinson, C. Giganti, S. Kuribayashi, R. Akutsu, M. Vagins, M. Yu, T. Kobata, S. Mine, D. Brailsford, T. Radermacher, A. Bubak, K. Iwamoto, A. Knox, T. Arihara, Y. Hayato, L. Ludovici, S. Parsa, J. Steinmann, T. Honjo, Y. Nakajima, G. Fiorillo, Hiroyuki Sekiya, F. Nova, Y. Oyama, Hyun-Chul Kim, V. Paolone, P. Novella, Jaroslaw Pasternak, K. Mavrokoridis, Y. Fujii, A. Konaka, J. L. Palomino, R. Fujita, D. Karlen, L. Pickering, C. Ruggles, G. Santucci, S. L. Liu, Z. Vallari, K. Wood, Masayuki Nakahata, C. Pidcott, Y. Uchida, E. D. Zimmerman, E. Mazzucato, A. Takeda, J. C. Nugent, Keigo Nakamura, C. Vilela, Kendall Mahn, A. Rychter, C. Checchia, A. Longhin, M. Friend, A. Shaykina, J. Lagoda, S. R. Dennis, Yoshihiro Suzuki, K. M. Tsui, C. M. Schloesser, Robert Wilson, C. Barry, A. Hiramoto, R.P. Kurjata, Marco Laveder, S. King, A. Izmaylov, A. C. Kaboth, S. P. Kasetti, J. Zalipska, R. Shah, T. Kobayashi, M. G. Catanesi, T. Hasegawa, A. Blondel, D. Sgalaberna, C. Jesús-Valls, Alexander Finch, L. N. Machado, J. Holeczek, Michelangelo Pari, Shuji Tanaka, G. De Rosa, J. G. Walsh, Y. Takeuchi, R. A. Owen, X. Junjie, H. Kikutani, A. Cervera, K. Yamamoto, D. R. Hadley, L. Marti-Magro, F. Bench, K. Zaremba, J. T. Haigh, O. Drapier, S. Yen, D. Cherdack, Y. Kato, S. Valder, A. Pritchard, T. Campbell, Y. Kataoka, M. Batkiewicz-Kwasniak, E. T. Atkin, K. Yasutome, V. A. Matveev, C. Metelko, C. Wret, T. Nakadaira, N. Akhlaq, T. Kajita, M. Lawe, T. Wachala, L. Maret, M. Tani, T. Sekiguchi, Stephanie Bron, C. Riccio, T. Dealtry, K. Abe, C. McGrew, M. Pavin, S. J. Jenkins, L. Koch, M. Guigue, T. Tsukamoto, Akitaka Ariga, D. Coplowe, A. Beloshapkin, M. Miura, F. Di Lodovico, A. A. Sztuc, Federico Sanchez, E. S. Pinzon Guerra, M. Tada, Vincenzo Berardi, G. A. Fiorentini, P. Paudyal, A. Bravar, M. Kabirnezhad, C. Andreopoulos, A. Zykova, W. Toki, Y. Awataguchi, D. Barrow, T. Ishii, P. N. Ratoff, Yu. G. Kudenko, Etam Noah, F. J. P. Soler, T. Kutter, S. L. Cartwright, T. Bonus, N. C. Hastings, D. G. Payne, H. Kubo, A. Nakamura, S. Nakayama, J. Calcutt, Y. Asada, Hiromasa Tanaka, P. Jonsson, Ahmed Ali, M. Hogan, Shigeki Aoki, G. C. Penn, L. Labarga, Alan Cosimo Ruggeri, Y. Nishimura, Gareth J. Barker, M. B. Smy, A. Knight, Y. Seiya, L. Munteanu, H. Sobel, T. Ishida, T. Odagawa, Xiao-yan Li, T. S. Nonnenmacher, S. Bienstock, M. Tajima, Yusuke Koshio, Teppei Katori, L. L. Kormos, H. M. O'Keeffe, E. Radicioni, M. Lamoureux, Y. Sonoda, J. P. Coleman, Laura Gutermuth Anthony, K. Kowalik, S. Zsoldos, S. Roth, C. Pistillo, A. Dabrowska, F. Shaker, T. Matsubara, D. L. Wark, G. Vasseur, V. Palladino, Patrick Dunne, N. Chikuma, J. A. Nowak, W. C. Parker, M. O. Wascko, A. Chappell, E. Kearns, Sy Suzuki, A. N. Khotjantsev, A. K. Ichikawa, J. F. Martin, M. Tzanov, M. Jakkapu, J. R. Wilson, M. Ishitsuka, W. Shorrock, J. Kisiel, Yuuki Nakano, S. Manly, P. F. Denner, A. Minamino, T. Yano, M. Antonova, K. Matsushita, A. D. Marino, R. Okada, T. Ogawa, Y. Katayama, S. Emery-Schrenk, M. Malek, S. Moriyama, Samira Hassani, T. A. Doyle, Jan T. Sobczyk, S. Dolan, C. Densham, A. Cudd, T. Koga, Oleg Mineev, C. Francois, M. Ziembicki, Yufeng Wang, M. Zito, Hidekazu Kakuno, Y. Yamada, G. Yang, S. B. Boyd, N. Izumi, B. A. Popov, B. Jamieson, A. Zalewska, T. Golan, A. Shvartsman, K. Fusshoeller, D. Bravo Berguño, Pablo Fernandez, Kate Scholberg, H. K. Tanaka, D. Vargas, A. C. Weber, J. Dumarchez, J. Schwehr, M. Posiadala-Zezula, G. Collazuol, Mark Scott, T. Yoshida, M. Cicerchia, W. G. S. Vinning, T. Maruyama, T. V. Ngoc, A. Shaikhiev, E. Reinherz-Aronis, K. Nishikawa, Masashi Yokoyama, N. T. Hong Van, J. Walker, Tsuyoshi Nakaya, C. Mauger, Masato Shiozawa, A. Kostin, D. Fukuda, S. Bhadra, L. Cook, L. O'Sullivan, Xianguo Lu, M. Hartz, André Rubbia, L. Magaletti, C. Yanagisawa, S. V. Cao, Ministerio de Economía y Competitividad (España), Abe, K., Akutsu, R., Ali, A., Alt, C., Andreopoulos, C., Anthony, L., Antonova, M., Aoki, S., Ariga, A., Ashida, Y., Atkin, E. T., Awataguchi, Y., Ban, S., Barbi, M., Barker, G. J., Barr, G., Barry, C., Batkiewicz-Kwasniak, M., Beloshapkin, A., Bench, F., Berardi, V., Berkman, S., Berns, L., Bhadra, S., Bienstock, S., Blondel, A., Bolognesi, S., Bourguille, B., Boyd, S. B., Brailsford, D., Bravar, A., Berguno, D. Bravo, Bronner, C., Bubak, A., Avanzini, M. Buizza, Calcutt, J., Campbell, T., Cao, S., Cartwright, S. L., Catanesi, M. G., Cervera, A., Chappell, A., Checchia, C., Cherdack, D., Chikuma, N., Christodoulou, G., Coleman, J., Collazuol, G., Cook, L., Coplowe, D., Cudd, A., Dabrowska, A., De Rosa, G., Dealtry, T., Denner, P. F., Dennis, S. R., Densham, C., Di Lodovico, F., Dokania, N., Dolan, S., Drapier, O., Dumarchez, J., Dunne, P., Eklund, L., Emery-Schrenk, S., Ereditato, A., Fernandez, P., Feusels, T., Finch, A. J., Fiorentini, G. A., Fiorillo, G., Francois, C., Friend, M., Fujii, Y., Fujita, R., Fukuda, D., Fukuda, R., Fukuda, Y., Gameil, K., Giganti, C., Golan, T., Gonin, M., Gorin, A., Guigue, M., Hadley, D. R., Haigh, J. T., Hamacher-Baumann, P., Hartz, M., Hasegawa, T., Hastings, N. C., Hayashino, T., Hayato, Y., Hiramoto, A., Hogan, M., Holeczek, J., Hong Van, N. T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishii, T., Ishitsuka, M., Iwamoto, K., Izmaylov, A., Jamieson, B., Jenkins, S. J., Jesus-Valls, C., Jiang, M., Johnson, S., Jonsson, P., Jung, C. K., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Karlen, D., Kasetti, S. P., Kataoka, Y., Katori, T., Kato, Y., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kim, H., Kim, J., King, S., Kisiel, J., Knight, A., Knox, A., Kobayashi, T., Koch, L., Koga, T., Konaka, A., Kormos, L. L., Koshio, Y., Kowalik, K., Kubo, H., Kudenko, Y., Kukita, N., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., Labarga, L., Lagoda, J., Lamoureux, M., Laveder, M., Lawe, M., Licciardi, M., Lindner, T., Litchfield, R. P., Liu, S. L., Li, X., Longhin, A., Ludovici, L., Lu, X., Lux, T., Nascimento Machado, L., Magaletti, L., Mahn, K., Malek, M., Manly, S., Maret, L., Marino, A. D., Martin, J. F., Maruyama, T., Matsubara, T., Matsushita, K., Matveev, V., Mavrokoridis, K., Mazzucato, E., Mccarthy, M., Mccauley, N., Mcfarland, K. S., Mcgrew, C., Mefodiev, A., Metelko, C., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Morrison, J., Mueller, Th. A., Munteanu, L., Murphy, S., Nagai, Y., Nakadaira, T., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K. G., Nakamura, K., Nakayama, S., Nakaya, T., Nakayoshi, K., Nantais, C., Ngoc, T. V., Niewczas, K., Nishikawa, K., Nishimura, Y., Nonnenmacher, T. S., Nova, F., Novella, P., Nowak, J., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Okumura, K., Okusawa, T., Oser, S. M., Owen, R. A., Oyama, Y., Palladino, V., Palomino, J. L., Paolone, V., Parker, W. C., Paudyal, P., Pavin, M., Payne, D., Penn, G. C., Pickering, L., Pidcott, C., Guerra, E. S. Pinzon, Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Pritchard, A., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ratoff, P. N., Reinherz-Aronis, E., Riccio, C., Rondio, E., Roth, S., Rubbia, A., Ruggeri, A. C., Rychter, A., Sakashita, K., Sanchez, F., Schloesser, C. M., Scholberg, K., Schwehr, J., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shah, R., Shaikhiev, A., Shaker, F., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Smirnov, A., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Steinmann, J., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tajima, M., Takeda, A., Takeuchi, Y., Tanaka, H. K., Tanaka, H. A., Tanaka, S., Thompson, L. F., Toki, W., Touramanis, C., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Uno, W., Vagins, M., Valder, S., Vallari, Z., Vargas, D., Vasseur, G., Vilela, C., Vinning, W. G. S., Vladisavljevic, T., Volkov, V. V., Wachala, T., Walker, J., Walsh, J. G., Wang, Y., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wilson, R. J., Wood, K., Wret, C., Yamada, Y., Yamamoto, K., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yen, S., Yershov, N., Yokoyama, M., Yoshida, T., Yu, M., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Ziembicki, M., Zimmerman, E. D., Zito, M., Zsoldos, S., Zykova, A., Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire Leprince-Ringuet (LLR), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), T2K, Science and Technology Facilities Council (STFC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), and ANR-19-CE31-0001,SUNCORE,Incertitudes systématiques dans les combinaisons de résultats d'oscillations de neutrinos(2019)
Subjects: electron, Physics::Instrumentation and Detectors, Monte Carlo method, far detector, Electron, KAMIOKANDE, antineutrino/mu: secondary beam, Other experiments, antineutrino/e: particle identification, 01 natural sciences, neutrino: flux, High Energy Physics - Experiment, charged current, High Energy Physics - Experiment (hep-ex), secondary beam [neutrino/mu], [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], neutrino/e: particle identification, measured [total cross section], detector [neutrino], Charged current, Physics, 0105 Mathematical Physics, J-PARC Lab, Detector, Monte Carlo [numerical calculations], Nuclear & Particles Physics, angular dependence, neutrino: detector, 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics, Neutrino, numerical calculations: Monte Carlo, Particle Physics - Experiment, scattering [neutrino], Nuclear and High Energy Physics, 530 Physics, Astrophysics::High Energy Astrophysical Phenomena, particle identification [antineutrino/e], FOS: Physical sciences, momentum dependence, secondary beam [antineutrino/mu], Nuclear physics, Momentum, differential cross section: measured, phase space, near detector, measured [differential cross section], 0103 physical sciences, neutrino: scattering, ddc:530, lcsh:Nuclear and particle physics. Atomic energy. Radioactivity, 010306 general physics, 0206 Quantum Physics, hep-ex, 010308 nuclear & particles physics, Scattering, particle identification [neutrino/e], background, Computer Science::Information Retrieval, High Energy Physics::Phenomenology, scintillation counter: target, flux [neutrino], neutrino/mu: secondary beam, total cross section: measured, target [scintillation counter], lcsh:QC770-798, High Energy Physics::Experiment, Electron neutrino, experimental results
Abstract: The electron (anti-)neutrino component of the T2K neutrino beam constitutes the largest background in the measurement of electron (anti-)neutrino appearance at the far detector. The electron neutrino scattering is measured directly with the T2K off-axis near detector, ND280. The selection of the electron (anti-)neutrino events in the plastic scintillator target from both neutrino and anti-neutrino mode beams is discussed in this paper. The flux integrated single differential charged-current inclusive electron (anti-)neutrino cross-sections, dσ/dp and dσ/d cos(θ), and the total cross-sections in a limited phase-space in momentum and scattering angle (p > 300 MeV/c and θ ≤ 45°) are measured using a binned maximum likelihood fit and compared to the neutrino Monte Carlo generator predictions, resulting in good agreement., Journal of High Energy Physics, 2020 (10), ISSN:1126-6708, ISSN:1029-8479
Published: 2020
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43. Overview of the ITER remote maintenance design and of the development activities in Europe

Author: David Hamilton, M. Saito, Philip Bates, M. Van Uffelen, D. Locke, C. Van Hille, Emilio Ruiz, J.P. Friconneau, Y. Noguchi, Chang-Hwan Choi, S. Murakami, Carlo Damiani, Roger Reichle, S. Bernal, L. Mont, Nobukazu Takeda, M. Lewczanin, S. Balagué, J. Sanchez Cuevas, Gregory Dubus, Salvador Esque, J.P. Martin, R. Shuff, T. Maruyama, Adrian Puiu, Carmen González, N. Van De Ven, J. Cornellá, B. Perrier, T. Ilkei, C. Annino, and J. Palmer
Subjects: Scope (project management), Computer science, Mechanical Engineering, Maintainability, 01 natural sciences, Maintenance system, 010305 fluids & plasmas, Procurement, Development (topology), Nuclear Energy and Engineering, 0103 physical sciences, Systems engineering, Key (cryptography), General Materials Science, 010306 general physics, Energy source, Plant design, Civil and Structural Engineering
Abstract: For a first-of-a-kind nuclear fusion reactor like ITER, remote maintainability of neutron-activated and contaminated components is one of the key aspects of plant design and operations, hence a fundamental ingredient of its success, as well as of the demonstration of long-term viability of fusion as an energy source. The whole ITER Remote Maintenance System (IRMS) is of unprecedented complexity and includes specifically developed technologies. Its procurement and start of operation will represent a major innovation to maintenance in hostile environments. Europe is a key contributor, with three remote handling (RH) systems, a.k.a. packages, plus a robotic inspection and metrology tool, currently under design. This paper gives an update on the status of design and procurement activities related to the IRMS. It will first introduce some key aspects of the reactor remote maintainability, and then give an overview of the present configuration of the global system. After this, the scope, status and challenges of the European (EU) packages will be illustrated in more detail, together with some key technological developments. Finally, the way all these efforts are coordinated will be presented together with the overall implementation scenario and milestones, and the way they fit with ITER construction and operation.
Published: 2018
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44. A minimum in the latitude variation of spread-F at March equinox

Author: A. K. Patra, T. Maruyama, V. L. Narayanan, and N. Balan
Subjects: Low-mid latitude spread-F, 010504 meteorology & atmospheric sciences, Anomaly (natural sciences), Short paper, lcsh:QE1-996.5, Theoretical models, lcsh:Geography. Anthropology. Recreation, Equinox, Atmospheric sciences, 01 natural sciences, Latitude, Minimum and maximum in spread-F, lcsh:Geology, lcsh:G, 0103 physical sciences, General Earth and Planetary Sciences, Environmental science, Crest, Longitude, Variation (astronomy), 010303 astronomy & astrophysics, 0105 earth and related environmental sciences
Abstract: This short paper presents the statistics of spread-F occurrence at four low-mid latitude locations (17.0° N, 21.2° N, 26.5° N and 36.5° N mag. lat.) in Japan longitude sector (~ 135° E) in March to April 2002, 2003 and 2006 (high, medium and low solar activity). The location of a spread-F minimum predicted by theoretical models is identified for the first time. The spread-F minimum occurs at the poleward side of the equatorial ionisation anomaly crest and shifts equatorward from ~ 25° N mag. lat. at high solar activity to below 17° N at low solar activity. The corresponding spread-F maximum occurring on the poleward side of the minimum also shifts equatorward from ~ 35° N (or beyond) at medium solar activity to 20°–25° N at low solar activity. The spread-F occurrence increases with decreasing solar activity at all locations especially at higher latitudes (> ~ 25° N) where there is almost no occurrence at high solar activity.
Published: 2018
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45. A multicenter, propensity score-matched retrospective study of preventing postoperative infection in robotic and laparoscopic minimally invasive surgeries; double-versus single-gloving

Author: T. Isobe, T. Kato, Hiroyuki Kamiya, Shuzo Hamamoto, Takashi Nagai, N. Matsuyama, R. Ando, Takashi Hamakawa, Yasuhiro Fujii, Rei Unno, Toshiki Etani, Atsushi Okada, A. Nakane, T. Hattori, T. Maruyama, Y. Ikegami, N. Kawai, Takahiro Yasui, and Kazumi Taguchi
Subjects: medicine.medical_specialty, business.industry, Urology, Propensity score matching, Postoperative infection, Medicine, Retrospective cohort study, business, Surgery
Published: 2021
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46. The Heavy Photon Search beamline and its performance

Author: F. X. Girod, M. Ungaro, C. Field, G. Kalicy, B. McKinnon, T. K. Nelson, T. Maruyama, A. P. Freyberger, S. Stepanyan, N. A. Baltzell, M. Holtrop, M. Ehrhart, K. Moffeit, S. Uemura, H. Vance, A. Odian, Hovanes Egiyan, R. Paremuzyan, J. Jaros, M. Oriunno, and M. Tiefenback
Subjects: Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, Photon, Physics::Instrumentation and Detectors, FOS: Physical sciences, 01 natural sciences, Dark photon, High Energy Physics - Experiment, law.invention, Nuclear physics, High Energy Physics - Experiment (hep-ex), law, 0103 physical sciences, Nuclear Experiment (nucl-ex), Nuclear Experiment, 010306 general physics, Instrumentation, Physics, Spectrometer, 010308 nuclear & particles physics, Detector, Collimator, Particle accelerator, Instrumentation and Detectors (physics.ins-det), Beamline, Cathode ray, Physics::Accelerator Physics
Abstract: The Heavy Photon Search (HPS) is an experiment to search for a hidden sector photon, aka a heavy photon or dark photon, in fixed target electroproduction at the Thomas Jefferson National Accelerator Facility (JLab). The HPS experiment searches for the e$^+$e$^-$ decay of the heavy photon with bump hunt and detached vertex strategies using a compact, large acceptance forward spectrometer, consisting of a silicon microstrip detector (SVT) for tracking and vertexing, and a PbWO$_4$ electromagnetic calorimeter for energy measurement and fast triggering. To achieve large acceptance and good vertexing resolution, the first layer of silicon detectors is placed just 10 cm downstream of the target with the sensor edges only 500 $\mu$m above and below the beam. Placing the SVT in such close proximity to the beam puts stringent requirements on the beam profile and beam position stability. As part of an approved engineering run, HPS took data in 2015 and 2016 at 1.05 GeV and 2.3 GeV beam energies, respectively. This paper describes the beam line and its performance during that data taking.
Published: 2017
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47. Crystallographic analysis on atomic-plane parallelisms between bcc precipitates and hcp matrix in recrystallized Zr-2.5Nb alloys

Author: Hiroaki Abe, R. Suzue, T. Maruyama, I. Okuma, Huilong Yang, Shinsuke Yamanaka, Hiroaki Muta, Yuhki Satoh, Yasunari Shinohara, Yanfen Li, Yoshitaka Matsukawa, Takeshi Toyama, and Jingjie Shen
Subjects: 010302 applied physics, Diffraction, Materials science, Polymers and Plastics, Zirconium alloy, Alloy, Metals and Alloys, Close-packing of equal spheres, Recrystallization (metallurgy), 02 engineering and technology, Cubic crystal system, engineering.material, 021001 nanoscience & nanotechnology, 01 natural sciences, Electronic, Optical and Magnetic Materials, Shear modulus, Crystallography, 0103 physical sciences, Ceramics and Composites, engineering, 0210 nano-technology, Electron backscatter diffraction
Abstract: The crystal orientation of body centered cubic (bcc) precipitates embedded in hexagonal close packed (hcp) matrix is usually assumed to follow the so-called Burgers orientation relationship; however, this orientation relationship may not be maintained in the case where the precipitation occurs in parallel with the recrystallization of matrix. The Zr-2.5Nb alloy is a typical example of such a case. In the present study crystal orientations of bcc precipitates (Nb-rich β2 phase and Zr-rich β1 phase) in fully recrystallized hcp Zr matrix have been analyzed by means of electron backscatter diffraction (EBSD) and transmission Kikuchi diffraction (TKD). Based on the Euler angles determined by EBSD/TKD, the parallelism of atomic planes was examined one by one. The analysis was performed on 100 precipitates for each composition. The crystal orientations of the Nb-rich precipitates were practically random, whereas 28% of the Zr-rich precipitates followed the Burgers orientation relationship. Moreover, the fraction of the Nb-rich precipitates whose slip planes, either {110} or {112}, were parallel to those of the hcp Zr matrix, { 10 1 ¯ 0 }, was no greater than 5%. These results support a tentative conclusion of our previous study that the Nb precipitates are ideal Orowan type strong obstacles against gliding dislocations due to the crystal mismatch, even though they are softer than the matrix in terms of shear modulus.
Published: 2017
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48. Search for Electron Antineutrino Appearance in a Long-baseline Muon Antineutrino Beam

Author: E. Rondio, N. McCauley, C. M. Nantais, K. Porwit, J. T. Haigh, M. McCarthy, Vladimir Volkov, Lester D.R. Thompson, M. Mezzetto, W. Toki, L. Molina Bueno, K. Nishikawa, A. A. Sztuc, E. S. Pinzon Guerra, M. Vagins, S. Mine, Xianguo Lu, F. Di Lodovico, M. Barbi, M. Tada, B. Radics, Masashi Yokoyama, C. Alt, K. M. Tsui, M. G. Catanesi, Yu. G. Kudenko, N. C. Hastings, N. T. Hong Van, Y. Takeuchi, K. Kowalik, J. Walker, R. Shah, S. V. Cao, V. Paolone, A. Knight, André Rubbia, B. Bourguille, L. Magaletti, M. Gonin, Y. Nishimura, G. De Rosa, J. G. Walsh, S. M. Oser, Tsuyoshi Nakaya, Alexander N. Smirnov, Th. A. Mueller, T. Towstego, Z. Vallari, K. Wood, R. A. Owen, M. Batkiewicz-Kwasniak, D. Karlen, L. Maret, R. Akutsu, H. M. O'Keeffe, Y. Sonoda, P. N. Ratoff, T. Kutter, S. P. Kasetti, C. Ruggles, F. Iacob, L. Berns, E. D. Zimmerman, A. Cervera, A. Mefodiev, M. Ikeda, K. Nakayoshi, Kimihiro Okumura, N. Kukita, M. Licciardi, N. Chikuma, A. N. Khotjantsev, J. C. Nugent, S. King, T. Feusels, S. Bolognesi, Y. Ashida, A. Beloshapkin, Teppei Katori, K. Yamamoto, C. Wret, M. Guigue, J. A. Nowak, M. Miura, A. Shaikhiev, A. Chappell, T. Okusawa, M. O. Wascko, E. Kearns, S. L. Liu, C. Yanagisawa, Lars Eklund, Y. Oyama, J. Calcutt, G. Fiorillo, S. Berkman, B. Quilain, T. A. Doyle, P. Paudyal, C. Bronner, E. Radicioni, K. Niewczas, Hyun-Chul Kim, A. Izmaylov, J. Steinmann, M. M. Khabibullin, M. Zito, Hidekazu Kakuno, P. Novella, K. Nakamura, R. Wendell, E. Reinherz-Aronis, Y. Fukuda, G. Christodoulou, S. L. Cartwright, Vincenzo Berardi, D. Barrow, O. Drapier, L. Pickering, F. J. P. Soler, G. Yang, J. L. Palomino, J. Zalipska, E. T. Atkin, Y. Nakajima, K. Sakashita, M. Kuze, L. Marti-Magro, L. Munteanu, Alan Cosimo Ruggeri, K. Zaremba, Laura Gutermuth Anthony, C. Vilela, D. Fukuda, D. Sgalaberna, Hiroyuki Sekiya, F. Nova, T. Matsubara, C. Wilkinson, C. Touramanis, Y. Kato, M. Tajima, R. Fujita, S. Yen, K. Yasutome, D. L. Wark, S. Bienstock, L. O'Sullivan, A. Knox, M. Jiang, D. R. Hadley, S. Ban, Yusuke Koshio, Kendall Mahn, G. Vasseur, J. Lagoda, Yoshihiro Suzuki, L. N. Machado, Antonio Ereditato, Federico Sanchez, A. C. Weber, D. Brailsford, W. G. S. Vinning, J. Kameda, Y. Hayato, L. Ludovici, S. Murphy, N. Yershov, M. Ishitsuka, C. Giganti, S. Kuribayashi, J. R. Wilson, C. Jesús-Valls, Alexander Finch, S. Nakayama, Masayuki Nakahata, C. Pidcott, W. Shorrock, Kevin Scott McFarland, T. Radermacher, M. Posiadala-Zezula, Robert Wilson, T. Maruyama, Sy Suzuki, T. Wachala, M. Yu, S. Moriyama, Y. Seiya, T. V. Ngoc, M. Antonova, C. Barry, Y. Uchida, C. Checchia, T. Yano, H. Sobel, T. Koga, R.P. Kurjata, G. Collazuol, T. S. Nonnenmacher, Mark Scott, T. Yoshida, P. Hamacher-Baumann, S. R. Dennis, Y. Fujii, C. M. Schloesser, Jungsang Kim, A. D. Marino, A. Longhin, M. Friend, A. Shaykina, A. Blondel, M. Lamoureux, Masato Shiozawa, A. Takeda, B. Jamieson, A. Zalewska, A. C. Kaboth, N. Dokania, G. A. Fiorentini, S. R. Johnson, T. Golan, S. Emery-Schrenk, J. Holeczek, S. Zsoldos, A. Pritchard, V. Palladino, A. Shvartsman, T. Kobayashi, G. C. Penn, T. Sekiguchi, D. Bravo Berguño, W. Uno, Ahmed Ali, C. Pistillo, C. Riccio, Pablo Fernandez, A. Dabrowska, M. B. Smy, A. Kostin, B. A. Popov, C. Metelko, D. Coplowe, T. Dealtry, S. Bhadra, L. Cook, G.D. Barr, M. Jakkapu, D. Vargas, Xiao-yan Li, J. Dumarchez, J. Schwehr, M. Hartz, A. Bravar, S. Dolan, T. Ishii, C. Densham, A. Cudd, Y. Yamada, H. Kubo, M. J. Wilking, P. Jonsson, S. B. Boyd, S. Roth, Keigo Nakamura, L. Labarga, K. Fusshoeller, K. Gameil, J. Morrison, W. C. Parker, A. Zykova, M. Pavin, S. J. Jenkins, Gareth J. Barker, D. G. Payne, A. Nakamura, Kate Scholberg, J. P. Coleman, F. Shaker, T. Tsukamoto, H. K. Tanaka, J. F. Martin, M. Tzanov, G. Zarnecki, A. Rychter, J. Kisiel, K. Matsushita, A. Hiramoto, A. K. Ichikawa, M. Buizza Avanzini, L. L. Kormos, T. Hasegawa, D. Cherdack, T. Campbell, S. Valder, K. Abe, Y. Kataoka, G. Pintaudi, C. McGrew, A. Gorin, L. Koch, C. Andreopoulos, T. Vladisavljevic, Thorsten Lux, T. Lindner, T. Kikawa, S. Suvorov, R. P. Litchfield, F. Bench, T. Kajita, M. Lawe, M. Kabirnezhad, A. T. Suzuki, Y. Nagai, C. K. Jung, Akitaka Ariga, T. Hayashino, R. Fukuda, E. Mazzucato, Y. Asada, Oleg Mineev, T. Nakadaira, Shigeki Aoki, M. Ziembicki, Yufeng Wang, M. Hogan, V. Matveev, T. Ishida, T. Odagawa, K. Mavrokoridis, A. Konaka, A. Bubak, H. A. Tanaka, K. Iwamoto, Jaroslaw Pasternak, Y. Awataguchi, Marco Laveder, Patrick Dunne, Jan T. Sobczyk, S. Manly, P. F. Denner, C. Francois, A. Minamino, M. Malek, Shuji Tanaka, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), T2K, Science and Technology Facilities Council (STFC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Ministerio de Economía y Competitividad (España), Abe, K., Akutsu, R., Ali, A., Alt, C., Andreopoulos, C., Anthony, L., Antonova, M., Aoki, S., Ariga, A., Asada, Y., Ashida, Y., Atkin, E. T., Awataguchi, Y., Ban, S., Barbi, M., Barker, G. J., Barr, G., Barrow, D., Barry, C., Batkiewicz-Kwasniak, M., Beloshapkin, A., Bench, F., Berardi, V, Berkman, S., Berns, L., Bhadra, S., Bienstock, S., Blondel, A., Bolognesi, S., Bourguille, B., Boyd, S. B., Brailsford, D., Bravar, A., Bravo Berguno, D., Bronner, C., Bubak, A., Avanzini, M. Buizza, Calcutt, J., Campbell, T., Cao, S., Cartwright, S. L., Catanesi, M. G., Cervera, A., Chappell, A., Checchia, C., Cherdack, D., Chikuma, N., Christodoulou, G., Coleman, J., Collazuol, G., Cook, L., Coplowe, D., Cudd, A., Dabrowska, A., De Rosa, G., Dealtry, T., Denner, P. F., Dennis, S. R., Densham, C., Di Lodovico, F., Dokania, N., Dolan, S., Doyle, T. A., Drapier, O., Dumarchez, J., Dunne, P., Eklund, L., Emery-Schrenk, S., Ereditato, A., Fernandez, P., Feusels, T., Finch, A. J., Fiorentini, G. A., Fiorillo, G., Francois, C., Friend, M., Fujii, Y., Fujita, R., Fukuda, D., Fukuda, R., Fukuda, Y., Fusshoeller, K., Gameil, K., Giganti, C., Golan, T., Gonin, M., Gorin, A., Guigue, M., Hadley, D. R., Haigh, J. T., Hamacher-Baumann, P., Hartz, M., Hasegawa, T., Hastings, N. C., Hayashino, T., Hayato, Y., Hiramoto, A., Hogan, M., Holeczek, J., Van, N. T. Hong, Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishii, T., Ishitsuka, M., Iwamoto, K., Izmaylov, A., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesus-Valls, C., Jiang, M., Johnson, S., Jonsson, P., Jung, C. K., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Karlen, D., Kasetti, S. P., Kataoka, Y., Katori, T., Kato, Y., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kim, H., Kim, J., King, S., Kisiel, J., Knight, A., Knox, A., Kobayashi, T., Koch, L., Koga, T., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Kowalik, K., Kubo, H., Kudenko, Y., Kukita, N., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., Labarga, L., Lagoda, J., Lamoureux, M., Laveder, M., Lawe, M., Licciardi, M., Lindner, T., Litcheld, R. P., Liu, S. L., Li, X., Longhin, A., Ludovici, L., Lu, X., Lux, T., Nascimento Machado, L., Magaletti, L., Mahn, K., Malek, M., Manly, S., Maret, L., Marino, A. D., Marti-Magro, L., Martin, J. F., Maruyama, T., Matsubara, T., Matsushita, K., Matveev, V, Mavrokoridis, K., Mazzucato, E., Mccarthy, M., Mccauley, N., Mcfarland, K. S., Mcgrew, C., Mefodiev, A., Metelko, C., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Morrison, J., Mueller, Th A., Munteanu, L., Murphy, S., Nagai, Y., Nakadaira, T., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K. G., Nakamura, K., Nakayama, S., Nakaya, T., Nakayoshi, K., Nantais, C., Ngoc, T., V, Niewczas, K., Nishikawa, K., Nishimura, Y., Nonnenmacher, T. S., Nova, F., Novella, P., Nowak, J., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Okumura, K., Okusawa, T., Oser, S. M., Owen, R. A., Oyama, Y., Palladino, V, Palomino, J. L., Paolone, V, Parker, W. C., Pasternak, J., Paudyal, P., Pavin, M., Payne, D., Penn, G. C., Pickering, L., Pidcott, C., Pintaudi, G., Guerra, E. S. Pinzon, Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Pritchard, A., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Rato, P. N., Reinherz-Aronis, E., Riccio, C., Rondio, E., Roth, S., Rubbia, A., Ruggeri, A. C., Ruggles, C. A., Rychter, A., Sakashita, K., Sanchez, F., Schloesser, C. M., Scholberg, K., Schwehr, J., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shah, R., Shaikhiev, A., Shaker, F., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Smirnov, A., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Steinmann, J., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tajima, M., Takeda, A., Takeuchi, Y., Tanaka, H. K., Tanaka, H. A., Tanaka, S., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Uno, W., Vagins, M., Valder, S., Vallari, Z., Vargas, D., Vasseur, G., Vilela, C., Vinning, W. G. S., Vladisavljevic, T., Volkov, V. V., Wachala, T., Walker, J., Walsh, J. G., Wang, Y., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wilson, R. J., Wood, K., Wret, C., Yamada, Y., Yamamoto, K., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yen, S., Yershov, N., Yokoyama, M., Yoshida, T., Yu, M., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Ziembicki, M., Zimmerman, E. D., Zito, M., Zsoldos, S., and Zykova, A.
Subjects: muon antineutrino beam, General Physics and Astronomy, antineutrino/mu: secondary beam, KAMIOKANDE, antineutrino/e: particle identification, 01 natural sciences, 09 Engineering, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), secondary beam [neutrino/mu], [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], neutrino/e: particle identification, QC, Physics, 02 Physical Sciences, J-PARC Lab, T2K experiment, electron antineutrino, T2K Collaboration, kinematics, Physical Sciences, Particle Physics - Experiment, T2K experiment in an accelerator-produced, General Physics, 530 Physics, Physics, Multidisciplinary, FOS: Physical sciences, particle identification [antineutrino/e], Neutrino beam, secondary beam [antineutrino/mu], Physics::Geophysics, Nuclear physics, 0103 physical sciences, mixing, ddc:530, 010306 general physics, 01 Mathematical Sciences, Muon, Science & Technology, particle identification [neutrino/e], hep-ex, background, neutrino/mu: secondary beam, antineutrino: oscillation, oscillation [antineutrino], Elementary Particles and Fields, High Energy Physics::Experiment, PMNS, Electron neutrino, Beam (structure), Free parameter, experimental results
Abstract: Electron antineutrino appearance is measured by the T2K experiment in an accelerator-produced antineutrino beam, using additional neutrino beam operation to constrain parameters of the Pontecorvo-Maki-Nakagawa-Sakata (PMNS) mixing matrix. T2K observes 15 candidate electron antineutrino events with a background expectation of 9.3 events. Including information from the kinematic distribution of observed events, the hypothesis of no electron antineutrino appearance is disfavored with a significance of 2.40 σ and no discrepancy between data and PMNS predictions is found. A complementary analysis that introduces an additional free parameter which allows non-PMNS values of electron neutrino and antineutrino appearance also finds no discrepancy between data and PMNS predictions., Physical Review Letters, 124 (16), ISSN:0031-9007, ISSN:1079-7114
Published: 2019
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49. P780Superiority of long-acting to short-acting loop diuretics in the treatment of heart failure with preserved ejection fraction: a sub-analysis of the CURE-HF Registry

Author: Sho Suzuki, Y Kanzaki, T Maruyama, K Yahikozawa, Hirohiko Motoki, Koichiro Kuwahara, N Hashizume, and Ayako Kozuka
Subjects: medicine.medical_specialty, business.industry, Furosemide, medicine.disease, Long acting, Internal medicine, Heart failure, Ischemic stroke, medicine, Cardiology, Myocardial infarction, Cardiology and Cardiovascular Medicine, Heart failure with preserved ejection fraction, business, medicine.drug
Abstract: Introduction Long-acting loop diuretics have a possibility of better prognosis compared to short-acting loop diuretics in patients with heart failure with preserved ejection fraction (HFpEF). Purpose To investigate the effect of long- and short-acting loop diuretics in patients with HFpEF. Methods From the Clue of Risk Stratification in Patients With Heart Failure Registry (CURE-HF Registry), we enrolled 301 consecutive patients with HFpEF (median age, 84 years; 55% female). Long-acting loop diuretics (azosemide) were administrated in 127 patients, and short-acting loop diuretics (furosemide) in 174 patients. We constructed Cox models for MACE (defined as a composite of all-cause death, non-fatal myocardial infarction, non-fatal stroke, and heart failure [HF] hospitalization). Results During a median follow-up of 317 [174–734] days, the primary endpoint occurred in 129 patients (42.8%). On multivariate inverse probability of treatment weighted (IPTW) Cox modeling, patients treated with long-acting loop diuretics had a significantly lower incidence of adverse events than those treated with short-acting loop diuretics (hazard ratio [HR], 0.39; 95% confidence interval [CI] 0.23–0.67; P=0.001). Furthermore, on multivariate IPTW Cox modeling for the secondary endpoints, all-cause mortality (HR, 0.50; 95% CI, 0.20–0.80; P=0.01) and unplanned hospitalization for decompensated HF (HR, 0.50; 95% CI, 0.28–0.89; P=0.018) were also reduced in patients treated with long-acting loop diuretics. Conclusions Long-acting loop diuretics reduced the risk of MACE compared to short-acting diuretics in patients with HFpEF.
Published: 2019
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50. Search for heavy neutrinos with the T2K near detector ND280

Author: C. Bronner, James R. Wilson, A. Bravar, S. King, A. Minamino, S. Ban, Robert Wilson, K. Yasutome, K. Nakamura, H. Kubo, P. Novella, P. Jonsson, K. Kowalik, E. Rondio, N. Chikuma, N. McCauley, C. M. Nantais, M. M. Khabibullin, A. N. Khotjantsev, Y. Nakajima, P. P. Koller, Federico Sanchez, D. R. Hadley, Y. Yamada, D. G. Payne, T. Wachala, A. Nakamura, L. Labarga, D. Sgalaberna, S. B. Boyd, S. Suvorov, R. P. Litchfield, K. Porwit, L. Molina Bueno, T. Inoue, R. Shah, Shin Sasaki, Jung-Hyun Kim, S. R. Johnson, G. De Rosa, G. A. Fiorentini, G.D. Barr, M. McCarthy, M. Malek, E. Scantamburlo, C. Barry, B. Radics, Xianguo Lu, D. Shaw, R.P. Kurjata, R. M. Berner, P. Lasorak, Patrick Dunne, K. Zaremba, S. Yen, R. A. Owen, F. Hosomi, Vladimir Volkov, M. Batkiewicz-Kwasniak, J. Morrison, S. Nakayama, A. Blondel, B. Bourguille, André Rubbia, A. Mefodiev, Lester D.R. Thompson, M. Mezzetto, Leïla Haegel, C. Pistillo, A. Dabrowska, K. Niewczas, W. Toki, J. Holeczek, Yusuke Suda, A. K. Ichikawa, G. Zarnecki, L. Magaletti, M. Ikeda, K. Nakayoshi, M. Vagins, M. Barbi, Y. Seiya, T. Thakore, C. Wret, Kimihiro Okumura, J. Steinmann, M. Buizza Avanzini, S. Mine, W. Uno, F. Di Lodovico, S. Dolan, M. Tada, C. Densham, F. Bench, A. Cudd, C. Metelko, A. Knight, S. Bolognesi, A. Rychter, J. L. Palomino, S. Manly, P. F. Denner, Hyun-Chul Kim, Todd D. Stewart, M. J. Wilking, Yu. G. Kudenko, K. E. Duffy, N. C. Hastings, A. Izmaylov, S. V. Cao, H. M. O'Keeffe, M. Gonin, Y. Nishimura, Akitaka Ariga, K. M. Tsui, T. Kajita, M. Lawe, P. Martins, H.A. Tanaka, S. Murphy, Y. Sonoda, J. Zalipska, S. M. Oser, T. Maruyama, M. Licciardi, T. Feusels, F. Iacob, M. Ishitsuka, Y. Oyama, K. Gameil, T. Lou, L. Berns, Shigeki Aoki, M. G. Catanesi, C. Yanagisawa, Y. Kato, M. O. Wascko, E. Radicioni, E. Kearns, B. Quilain, Y. Azuma, Sy Suzuki, M. Kabirnezhad, J. A. Nowak, Laura Gutermuth Anthony, A. Chappell, V. Matveev, Alexander Finch, H. Sobel, T. S. Nonnenmacher, T. Matsubara, D. L. Wark, J. T. Haigh, C. Jesus, T. Okusawa, C. Wilkinson, M. Antonova, Ahmed Ali, A. T. Suzuki, Y. Nagai, M. Lamoureux, B. Rossi, M. B. Smy, S. Yamasu, B. Jamieson, A. Zalewska, T. Golan, T. Radermacher, M. Yu, S. Zsoldos, C. K. Jung, C. Touramanis, Jan T. Sobczyk, M. Jiang, Antonio Ereditato, A. Pritchard, V. Palladino, K. Iwamoto, Xiao-yan Li, T. Hayashino, N. Yershov, A. A. Sztuc, E. S. Pinzon Guerra, T. Sekiguchi, C. Riccio, S. Emery-Schrenk, T. Yano, Pablo Fernandez, R. Wendell, Marco Laveder, Kevin Scott McFarland, T. Dealtry, C. Francois, K. Mavrokoridis, A. D. Marino, D. Vargas, A. Konaka, J. Kameda, J. Dumarchez, J. Schwehr, A. Hiramoto, T. Nakadaira, C. Giganti, T. Hasegawa, Ryuji Tamura, T. Kobayashi, C. Vilela, M. Miura, R. Tacik, D. Fukuda, T. Campbell, Y. Fujii, Z. J. Liptak, P. Paudyal, M. Hogan, Y. Awataguchi, E. Mazzucato, F. Gizzarelli, J. P. Lopez, A. Takeda, A. C. Kaboth, T. Ishida, A. Zykova, Oleg Mineev, L. O'Sullivan, S. Berkman, S. L. Cartwright, M. Ziembicki, O. Drapier, R. A. Intonti, L. L. Kormos, Yufeng Wang, Y. Takeuchi, L. Maret, P. N. Ratoff, T. Kutter, Teppei Katori, Hiroyuki Sekiya, R. Fujita, Kendall Mahn, P. Hamacher-Baumann, N. Dokania, Alexander N. Smirnov, Th. A. Mueller, R. Akutsu, G. Fiorillo, L. Pickering, J. Lagoda, Yoshihiro Suzuki, A. Knox, Y. Hayato, L. Ludovici, Keigo Nakamura, T. Vladisavljevic, Thorsten Lux, T. Lindner, W. Oryszczak, D. Cherdack, K. Abe, C. McGrew, L. Koch, C. Andreopoulos, V. Paolone, Z. Vallari, W. Y. Ma, Gareth J. Barker, E. D. Zimmerman, J. P. Coleman, A. Cervera, K. Yamamoto, F. Shaker, K. Nishikawa, Vincenzo Berardi, Alan Cosimo Ruggeri, D. Coplowe, T. Ishii, S. Bienstock, Masashi Yokoyama, N. T. Hong Van, G. Vasseur, J. Walker, D. Karlen, Tsuyoshi Nakaya, Masato Shiozawa, S. Moriyama, S. Bhadra, M. Hartz, A. Shaikhiev, T. Koga, E. Reinherz-Aronis, P. Stowell, M. Zito, Hidekazu Kakuno, G. Yang, A. C. Weber, A. Longhin, M. Friend, A. Shaykina, M. Posiadala-Zezula, G. Collazuol, Mark Scott, M. Pavin, T. Yoshida, T. Tsukamoto, Y. Ashida, Y. Fukuda, G. Christodoulou, Y. Nakanishi, K. Sakashita, M. Kuze, B. A. Popov, S. Roth, Masayuki Nakahata, C. Pidcott, Y. Uchida, C. Checchia, W. C. Parker, Kate Scholberg, H. K. Tanaka, J. F. Martin, M. Tzanov, J. Kisiel, J. Calcutt, Yusuke Koshio, D. Brailsford, S. R. Dennis, C. M. Schloesser, UAM. Departamento de Física Teórica, Abe, K., Akutsu, R., Ali, A., Andreopoulos, C., Anthony, L., Antonova, M., Aoki, S., Ariga, A., Ashida, Y., Awataguchi, Y., Azuma, Y., Ban, S., Barbi, M., Barker, G. J., Barr, G., Barry, C., Batkiewicz-Kwasniak, M., Bench, F., Berardi, V., Berkman, S., Berner, R. M., Berns, L., Bhadra, S., Bienstock, S., Blondel, A., Bolognesi, S., Bourguille, B., Boyd, S. B., Brailsford, D., Bravar, A., Bronner, C., Buizza Avanzini, M., Calcutt, J., Campbell, T., Cao, S., Cartwright, S. L., Catanesi, M. 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K., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Karlen, D., Katori, T., Kato, Y., Kearns, E., Khabibullin, M., Khotjantsev, A., Kim, H., Kim, J., King, S., Kisiel, J., Knight, A., Knox, A., Kobayashi, T., Koch, L., Koga, T., Koller, P. P., Konaka, A., Kormos, L. L., Koshio, Y., Kowalik, K., Kubo, H., Kudenko, Y., Kurjata, R., Kutter, T., Kuze, M., Labarga, L., Lagoda, J., Lamoureux, M., Lasorak, P., Laveder, M., Lawe, M., Licciardi, M., Lindner, T., Liptak, Z. J., Litchfield, R. P., Li, X., Longhin, A., Lopez, J. P., Lou, T., Ludovici, L., Lu, X., Lux, T., Magaletti, L., Mahn, K., Malek, M., Manly, S., Maret, L., Marino, A. D., Martin, J. F., Martins, P., Maruyama, T., Matsubara, T., Matveev, V., Mavrokoridis, K., Ma, W. Y., Mazzucato, E., Mccarthy, M., Mccauley, N., Mcfarland, K. S., Mcgrew, C., Mefodiev, A., Metelko, C., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Molina Bueno, L., Moriyama, S., Morrison, J., Mueller, T. A., Murphy, S., Nagai, Y., Nakadaira, T., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K. G., Nakamura, K., Nakamura, K. D., Nakanishi, Y., Nakayama, S., Nakaya, T., Nakayoshi, K., Nantais, C., Niewczas, K., Nishikawa, K., Nishimura, Y., Nonnenmacher, T. S., Novella, P., Nowak, J., O'Keeffe, H. M., O'Sullivan, L., Okumura, K., Okusawa, T., Oryszczak, W., Oser, S. M., Owen, R. A., Oyama, Y., Palladino, Vittorio, Palomino, J. L., Paolone, V., Parker, W. C., Paudyal, P., Pavin, M., Payne, D., Pickering, L., Pidcott, C., Pinzon Guerra, E. S., Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Pritchard, A., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ratoff, P. N., Reinherz-Aronis, E., Riccio, C., Rondio, E., Rossi, B., Roth, S., Rubbia, A., Ruggeri, ALAN COSIMO, Rychter, A., Sakashita, K., Sanchez, F., Sasaki, S., Scantamburlo, E., Schloesser, C. M., Scholberg, K., Schwehr, J., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shah, R., Shaikhiev, A., Shaker, F., Shaw, D., Shaykina, A., Shiozawa, M., Smirnov, A., Smy, M., Sobczyk, J. T., Sobel, H., Sonoda, Y., Steinmann, J., Stewart, T., Stowell, P., Suda, Y., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tacik, R., Tada, M., Takeda, A., Takeuchi, Y., Tamura, R., Tanaka, H. K., Tanaka, H. A., Thakore, T., Thompson, L. F., Toki, W., Touramanis, C., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Uno, W., Vagins, M., Vallari, Z., Vargas, D., Vasseur, G., Vilela, C., Vladisavljevic, T., Volkov, V. V., Wachala, T., Walker, J., Wang, Y., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wilson, R. J., Wret, C., Yamada, Y., Yamamoto, K., Yamasu, S., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yen, S., Yershov, N., Yokoyama, M., Yoshida, T., Yu, M., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Ziembicki, M., Zimmerman, E. D., Zito, M., Zsoldos, S., Zykova, A., Science and Technology Facilities Council (STFC), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), T2K, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Ministerio de Ciencia, Innovación y Universidades (España), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), and Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)
Subjects: decay modes [neutrino], GENERAL-THEORY, mixing [neutrino], Physics::Instrumentation and Detectors, neutrino: heavy: search for, KAMIOKANDE, 01 natural sciences, High Energy Physics - Experiment, Physics, Particles & Fields, High Energy Physics - Experiment (hep-ex), LIMITS, secondary beam [neutrino/mu], neutrino: decay modes, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Particle Physics Experiments, neutrino: mass, media_common, Physics, VMSM, J-PARC Lab, statistical analysis: Bayesian, K: decay, heavy neutrinos, T2K Experiment, Time Projection Chambers, mass dependence, General theory, T2K Experiment, Time Projection Chambers, Physical Sciences, Christian ministry, data analysis method, FOS: Physical sciences, Library science, heavy: search for [neutrino], Astronomy & Astrophysics, Bayesian [statistical analysis], near detector, 0103 physical sciences, DARK-MATTER, media_common.cataloged_instance, ddc:530, Early career, European union, S077A00, 010306 general physics, S077A01, heavy neutrinos, Science & Technology, 010308 nuclear & particles physics, background, hep-ex, High Energy Physics::Phenomenology, Física, neutrino/mu: secondary beam, time projection chamber, decay [K], mass [neutrino], Hypothetical particle physics models Particle phenomena, High Energy Physics::Experiment, neutrino: mixing, statistical, experimental results
Abstract: This paper reports on the search for heavy neutrinos with masses in the range 140, Physical Review D, 100 (5), ISSN:1550-7998, ISSN:0556-2821, ISSN:1550-2368
Published: 2019
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