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1. P893 Left ventricular flow energetics predicts worsening heart failure in dilated cardiomyopathy

Author: J Cho, T. Uejima, Takeshi Yamashita, L Takahashi, T Chikamori, and H Hayama
Subjects: medicine.medical_specialty, business.industry, Energetics, Dilated cardiomyopathy, General Medicine, medicine.disease, Flow (mathematics), Heart failure, Internal medicine, Cardiology, Medicine, Radiology, Nuclear Medicine and imaging, Cardiology and Cardiovascular Medicine, business
Abstract: Background Blood flows through healthy hearts form optimal flow structures; they store flow kinetic energy (KE) that can be used for ejection. In contrast, in failing hearts, intracardiac flows become disorganized so that they may be energetically inefficient. However, it remained unknown whether left ventricular (LV) flow energetics prognosticates in heart failure. Methods This study included 61 patients with dilated cardiomyopathy (DCM). The temporal change in KE during early diastole (ED), atrial contraction (AC) and isovolumic contraction (IVC) was measured using Vector Flow Mapping particle tracking (Hitachi, figure top). LV inflow (total flow) were divided, based on whether they were ejected (direct flow, DF) or stayed in LV (retained flow, RF) in the following systole. KE of DF can be made use of for ejection, whereas KE of RF is supposed to be wasted. Diastolic function was graded, according to current EACVI/ASE guidelines. The patients were followed up for three years. Primary endpoint was hospitalization for worsening heart failure (WHF). Results 12 patients had hospitalizations for WHF in the follow-up period. KE of total flow did not show any significant difference through the cardiac cycle between patients with and without WHF. KE of DF was slightly, but not significantly, smaller (ED: p = 0.252, AC: p = 0.119, IVC: p = 0.122), and KE of RF was slightly, but not significantly, larger (ED: p = 0.971, AC: p = 0.085, IVC: p = 0.134) in patients with WHF than those without events. The ratio of DF and RF (DF/RF ratio) showed significant differences between these two groups, especially from AC through IVC (figure, bottom-left). Cox proportional hazard analyses demonstrated that DF/RF ratio during IVC showed a significant correlation with clinical outcomes (p = 0.033, hazard ratio = 0.067). It remained significant even after adjusted for diastolic function grade (p = 0.046, hazard ratio = 0.074). Kaplan-Meier analysis confirmed the above results (figure, bottom-right). Conclusion: Efficiency of KE recruitment for LV ejection during IVC is associated with clinical outcomes in DCM. Abstract P893 Figure. LISA
Published: 2020
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2. Effectiveness of early administration of tranexamic acid in patients with severe trauma

Author: A Shiraishi, S Kushimoto, Y Otomo, H Matsui, A Hagiwara, K Murata, M Hayakawa, K Maekawa, D Saitoh, H Ogura, J Sasaki, T Shibusawa, T Uejima, A Yaguchi, M Takeda, H Ishikura, Y Nakamura, D Kudo, N Kaneko, T Matsuoka, Y Hagiwara, N Morimura, S Furugori, H Kato, T Kanemura, G Mayama, S Kim, O Takasu, and K Nishiyama
Subjects: Adult, Male, Blood transfusion, medicine.medical_treatment, Hemorrhage, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Blood Transfusion, In patient, 030212 general & internal medicine, Propensity Score, Aged, Retrospective Studies, business.industry, 030208 emergency & critical care medicine, Retrospective cohort study, Middle Aged, Antifibrinolytic Agents, Treatment Outcome, Tranexamic Acid, Severe trauma, Brain Injuries, Anesthesia, Propensity score matching, Injury Severity Score, Female, Surgery, Observational study, business, Tranexamic acid, medicine.drug
Abstract: Background A reduction in mortality with the early use of tranexamic acid has been demonstrated in severely injured patients who are bleeding. However, the modest treatment effect with no reduction in blood transfusion has raised concerns. The aim of the present study was to estimate the effectiveness of regular use of tranexamic acid in severely injured patients. Methods This multicentre observational study used retrospectively collected data from consecutive injured patients (Injury Severity Score at least 16) treated in 15 Japanese academic institutions in 2012. A propensity score-matched analysis compared patients who did or did not receive tranexamic acid administration within 3 h of injury. Study outcomes included 28-day all-cause and cause-specific mortality, and need for blood transfusion. Results Of 796 eligible subjects, 281 were treated with tranexamic acid. Propensity score matching selected a total of 500 matched subjects (250 in each group). Tranexamic acid administration was associated with lower 28-day mortality (10·0 versus 18·4 per cent; difference −8·4 (95 per cent c.i. –14·5 to −2·3) per cent) and lower 28-day mortality from primary brain injury (6·0 versus 13·2 per cent; difference −7·2 (−12·3 to −2·1) per cent). However, there was no significant difference between groups in the need for blood transfusion (33·2 versus 34·8 per cent; difference −1·6 (−9·9 to 6·7) per cent). Conclusion Early tranexamic acid use was associated with reduced mortality in severely injured patients, in particular those with a primary brain injury.
Published: 2017
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3. Poster Session 1The imaging examination and quality assessmentP185Why did the normal values of the left and right atrial volumes increase in the recent chamber quantification guidelines update?P186Atrial electromechanical delay, Left Atrial mechanical functions and longitudinal left ventricular strain in pre-diabetic patientsP187A web-based platform for e-training in echocardiographyP188Righ atrial size as a marker of success in electrical cardioversion in patients with persistent atrial fibrillationP189Echocardiographic assessment of left atrial dimensions and function in a healthy populationP190Impact of carotid artery revascularization on the cognitive and functional outcome and cerebral flow on TCD and brain MRI in patients with symptomatic carotid artery stenosis: a preliminary reportP191Aortic elasticity is impaired in hypereosinophilic syndromeP192Disturbed intracardiac flow transit prognosticates early decompensation in dilated cardiomyopathyP193Ultrasound guided treatment in acute heart failureP194Determinants of impaired global longitudinal function in middle-aged subjects free of cardiovascular diseaseP195Left ventricular remodeling in asymptomatic heart failure: classification and prognostic evaluationP196Restricted displacement of lateral right ventricular wall: a physiopathological explanation of geometrical and functional cardiac changes after cardiac surgeryP197A novel method to image intracardiac flow stagnation for the risk stratification for thrombosisP198Magnetic resonance imaging of anomalous origin of the left coronary artery from the pulmonary artery in children older than 4 monthsP199Coronary flow reserve is improved by LDL apheresis in patients with familial hypercholesterolemia and chronic ischemic heart diseaseP200 High velocities in the proximal part of the coronary arteries during routine echocardiography can predict nearest prognosisP201Recovery potential of the right ventricular function in the setting of a first STEMI treated by primary PCI: an echocardiographic studyP202Severe aortic stenosis patients with preserved ejection fraction according to flow and gradient classification: prevalence and outcomesP203Is basal left ventricular ejection time able to predict the severity of aortic stenosis in patients with depressed ejection fraction?P204Acceleration time in aortic stenosis: a new echocardiographic diagnostic parameterP205Application of novel Doppler indices of stenosis severity in the assessment of rheumatic mitral stenosis beyond conventional valve area and transvalvular gradientsP206Comparison of conventional echo score in patients with symptomatic rheumatic mitral stenosis: transesophageal echocardiography versus transthoracic echocardiographyP207Speckle-tracking echocardiography in evaluation early left ventricular systolic dysfunction in asymptomatic aortic regurgitation patients with good left ventricular ejection fractionP208Expansible aortic ring annuloplasty: mid-term results of aortic valve repairP209Papillary muscle dysfunction: insights into mitral valve prolapse using speckle tracking imaging

Author: L. Ring, Z. Hlubocka, V. Mizariene, YH. Park, A. Chong, D. Ruiz Fernandez, AS. Lazaro Mendes, JM. Monteagudo Ruiz, M. Stoian, A. Zagatina, E. Pasanisi, AJR Jurko, H. Nishikawa, A. Garcia Martin, I. Fabiani, I. Ceponiene, J. Oehman, T. Uejima, A. Nemes, R. Badacz, R W J Van Grootel, C. Doering, R. Conte, TAMER Moustafa, K. Kebed, E. Kruse, K. Addetia, B. Ciszek, M. Thykattil, B. Guile, RM. Lang, V. Mor-Avi, RAGAB Mahfouz, AHMED Elzayat, MOHAMD Goda, MARWA Gad, F. Sansone, F. Napoli, A. Tonacci, M. Raciti, P. Landi, A. Grande, L. Ait-Ali, K. Sveric, U. Richter, RH. Strasser, C. Wunderlich, ME. Menting, JS. Mcghie, M. Strachinaru, WB. Vletter, ML. Geleijnse, JW. Roos-Hesselink, AE. Van Den Bosch, A. Kablak-Ziembicka, M. Urbanczyk-Zawadzka, RP. Banys, P. Musialek, P. Pieniazek, S. Mleczko, K. Zmudka, T. Przewlocki, I. Marton, P. Domsik, A. Kalapos, E. Posfai, S. Modok, Z. Borbenyi, T. Forster, L. Takahashi, H. Semba, H. Sawada, T. Yamashita, R. Jurkevicius, J. Petkeviciene, O. Gustiene, E. Tamuleviciute-Prasciene, J. Motiejunaite, R. Slapikas, NR. Pugliese, S. La Carrubba, F. Antonini Canterin, P. Colonna, P. Caso, F. Benedetto, R. Citro, S. Carerj, V. Di Bello, JL. Moya Mur, C. Lazaro Rivera, LM. Rincon Diaz, J. Miguelena Hycka, A. Garcia Lledo, JJ. Jimenez Nacher, C. Fernandez-Golfin, J. Rodriguez-Roda, JL. Zamorano, A. Jurko, T. Jurko, J. Mistinova-Polakova, F. Sbrana, C. Petersen, F. Bigazzi, B. Dal Pino, M. Coceani, A. Ripoli, M. Pianelli, R. Luciani, T. Sampietro, N. Zhuravskaya, Y. Vareldzhyan, M. Kamenskikh, D. Shmatov, D. Zamfir, A. Vijiiac, D. Pitic, G. Tamasescu, S. Onciul, R. Onut, C. Stefan, M. Dorobantu, A. Gonzalez-Gomez, C. Izurieta, A. Marco, GL. Alonso Salinas, R. Hinojar Baydes, E. Casas Rojo, AR. Ferreira, J. Moura Ferreira, L. Leite, AP. Oliveira, N. Ribeiro, AJ. Barbosa, R. Mata Martins, D. Ramos, M. Pego, S. Gamaza Chulian, E. Diaz Retamino, S. Camacho Freire, A. Gutierrez Barrios, J. Oneto Otero, M. Bansal, HK. Grewal, RR. Kasliwal, S. Wahi, SH. Lee, DS. Lee, JM. Hwang, JS. Kim, JH. Kim, KJ. Chun, M. Bieseviciene, R. Verseckaite, R. Jonkaitiene, J. Janenaite, G. Dostalova, J. Hlubocky, R. Novotny, V. Vondracek, J. Lindner, A. Linhart, and NK. Preston
Subjects: Pediatrics, medicine.medical_specialty, business.industry, medicine, Follow up studies, Radiology, Nuclear Medicine and imaging, Regression analysis, General Medicine, Longitudinal function, Disease, Cardiology and Cardiovascular Medicine, business, Cohort study
Published: 2016
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4. Rapid Fire Abstract: Emerging imaging techniques303Myocardial stiffness assessment using shear wave imaging in healthy adult population302Intracardiac vortex intensity predicts early decompensation in dilated cardiomyopathy304A quantitative and qualitative characterization of the intraventricular blood flow of the normal human left ventricle using a contrast-tracking echo-PIV technique305Speckle tracking derived diastolic strain rate is an independent determinant of cardiac magnetic resonance detected myocardial fibrosis in patients with Fabry disease306Head to head comparison of global and regional 2D speckle tracking strain vs cardiac magnetic resonance tagging in a multicenter validation study307A twisting left ventricular ultrasound phantom for evaluation of 3D speckle tracking twist measurements308A new 2D-strain index to improve cardiovascular risk stratification in heart failure with reduced and mid-range ejection fraction309Adding speckle tracking echocardiography to visual assessment improves the detection of chronic myocardial infarction

Author: DVJ Zaar, C. Mornos, JJ. Hjertaas, MS. Amzulescu, K. Hu, VR. Piro, L. Takahashi, O. Villemain, M. Correia, E. Mousseaux, J. Baranger, S. Zarka, M. Pernot, E. Messas, T. Uejima, H. Nishikawa, H. Semba, H. Sawada, T. Yamashita, O. Piro, N. Piro, D. Liu, D. Oder, S. Herrmann, G. Ertl, F. Weidemann, C. Wanner, S. Stoerk, P. Nordbeck, H. Langet, E. Saloux, A. Manrique, L. Boileau, A. Slimani, P. Allain, C. Roy, A. Pasquet, M. De Craene, D. Vancraeynest, AC. Pouleur, JL. Vanoverschelde, B L M Gerber, K. Matre, A. Ionac, L. Petrescu, A. Mornos, M. Lazar, R. Sosdean, D. Cozma, M. Van Mourik, MW. Smulders, VL. Passos, S. Schalla, C. Knackstedt, G. Schummers, O. Gjesdal, T. Edvardsen, and SC. Bekkers
Subjects: Radiology, Nuclear Medicine and imaging, General Medicine, Cardiology and Cardiovascular Medicine
Published: 2016
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5. Rapid Fire Abstract: Diastology in health and disease420Added value over current diastology indices of Doppler-derived pulmonary artery diastolic pressure to estimate pulmonary wedge pressure421Intraventricular velocity difference and velocity gradient along the early diastolic filling streamline as new measurements to assess diastolic dysfunction by vector flow mapping422A new testing approach for mapping two-dimensional intraventricular pressure gradient - initial report -423Left ventricular diastolic abnormalities other than valvular disease in antiphospholipid syndrome: an echocardiographic study424Quantification of diastolic dysfunction by the dominant impact of age on diastolic function - The biomathematical impact on risk factor assessment425Echocardiographic subanalysis: correlation of the E/E-ratio to NT-BNP426CMR-derived metrics of interstitial myocardial fibrosis: which parameter is better associated to the pathophysiology correlates of heart failure with preserved ejection-fraction?427Comparison of the myocardial stiffness of the left ventricle between elite athletes and the general population. Study with the use of tissue Doppler imaging

Author: K. Yiangou, P. Monney, S. Stoebe, H. Von Bibra, M. Lembo, H. Semba, B. Berlot, P. Barbier, MC Scali, A. Simioniuc, C. Cucco, M. Guglielmo, G. Savioli, FL. Dini, JL. Moya Mur, D. Rodriguez Munoz, E. Casas Rojo, JJ. Jimenez Nacher, A. Garcia Martin, R. Hinojar, A. Gonzalez Gomez, B. Jug, C. Fernandez Golfin, JL. Zamorano, T. Uejima, H. Nishikawa, L. Takahashi, H. Sawada, T. Yamashita, A. Tufano, A. Nardo, A. Buonauro, V. Fazio, V. Schiano-Lomoriello, C. Santoro, S. Cocozza, G. Di Minno, B. Trimarco, M. Galderisi, C. Leclerque, T. Schuster, S. Zeynalova, S. Wirkner, A. Tarr, S. Tautenhahn, D. Jurisch, G. Farese, D. Pfeiffer, A. Hagendorff, M. Loeffler, S. Hugelshofer, PG. Masci, G. Vincenti, T. Rutz, J. Schwitter, CH. Azina, M. Kassianides, M. Ioannides, K. Englezopoulos, CH. Tountas, A. Theodosis-Georgilas, and D. Beldekos
Subjects: Radiology, Nuclear Medicine and imaging, General Medicine, Cardiology and Cardiovascular Medicine
Published: 2016
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6. Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

Author: null Author et al, R. M. Bateman, M. D. Sharpe, J. E. Jagger, C. G. Ellis, J. Solé-Violán, M. López-Rodríguez, E. Herrera-Ramos, J. Ruíz-Hernández, L. Borderías, J. Horcajada, N. González-Quevedo, O. Rajas, M. Briones, F. Rodríguez de Castro, C. Rodríguez Gallego, F. Esen, G. Orhun, P. Ergin Ozcan, E. Senturk, C. Ugur Yilmaz, N. Orhan, N. Arican, M. Kaya, M. Kucukerden, M. Giris, U. Akcan, S. Bilgic Gazioglu, E. Tuzun, R. Riff, O. Naamani, A. Douvdevani, R. Takegawa, H. Yoshida, T. Hirose, N. Yamamoto, H. Hagiya, M. Ojima, Y. Akeda, O. Tasaki, K. Tomono, T. Shimazu, S. Ono, T. Kubo, S. Suda, T. Ueno, T. Ikeda, H. Ogura, H. Takahashi, J. Kang, Y. Nakamura, T. Kojima, Y. Izutani, T. Taniguchi, M. O, C. Dinter, J. Lotz, B. Eilers, C. Wissmann, R. Lott, M. M. Meili, P. S. Schuetz, H. Hawa, M. Sharshir, M. Aburageila, N. Salahuddin, V. Chantziara, S. Georgiou, A. Tsimogianni, P. Alexandropoulos, A. Vassi, F. Lagiou, M. Valta, G. Micha, E. Chinou, G. Michaloudis, A. Kodaira, H. Imaizumi, M. V. De la Torre-Prados, A. Garcia-De la Torre, A. Enguix-Armada, A. Puerto-Morlan, V. Perez-Valero, A. Garcia-Alcantara, N. Bolton, J. Dudziak, S. Bonney, A. Tridente, P. Nee, G. Nicolaes, M. Wiewel, M. Schultz, K. Wildhagen, J. Horn, R. Schrijver, T. Van der Poll, C. Reutelingsperger, S. Pillai, G. Davies, G. Mills, R. Aubrey, K. Morris, P. Williams, P. Evans, E. G. Gayat, J. Struck, A. Cariou, N. Deye, B. Guidet, S. Jabert, J. Launay, M. Legrand, M. Léone, M. Resche-Rigon, E. Vicaut, A. Vieillard-Baron, A. Mebazaa, R. Arnold, M. Capan, A. Linder, P. Akesson, M. Popescu, D. Tomescu, C. L. Sprung, R. Calderon Morales, G. Munteanu, E. Orenbuch-Harroch, P. Levin, H. Kasdan, A. Reiter, T. Volker, Y. Himmel, Y. Cohen, J. Meissonnier, L. Girard, F. Rebeaud, I. Herrmann, B. Delwarde, E. Peronnet, E. Cerrato, F. Venet, A. Lepape, T. Rimmelé, G. Monneret, J. Textoris, N. Beloborodova, V. Moroz, A. Osipov, A. Bedova, Y. Sarshor, A. Pautova, A. Sergeev, E. Chernevskaya, J. Odermatt, R. Bolliger, L. Hersberger, M. Ottiger, M. Christ-Crain, B. Mueller, P. Schuetz, N. K. Sharma, A. K. Tashima, M. K. Brunialti, F. R. Machado, M. Assuncao, O. Rigato, R. Salomao, S. C. Cajander, G. Rasmussen, E. Tina, B. Söderquist, J. Källman, K. Strålin, A. L. Lange, J. S. Sundén-Cullberg, A. M. Magnuson, O. H. Hultgren, P. Van der Geest, M. Mohseni, J. Linssen, R. De Jonge, S. Duran, J. Groeneveld, R. Miller, B. K. Lopansri, L. C. McHugh, A. Seldon, J. P. Burke, J. Johnston, R. Reece-Anthony, A. Bond, A. Molokhia, C. Mcgrath, E. Nsutebu, P. Bank Pedersen, D. Pilsgaard Henriksen, S. Mikkelsen, A. Touborg Lassen, R. Tincu, C. Cobilinschi, Z. Ghiorghiu, R. Macovei, M. A. Wiewel, M. B. Harmon, L. A. Van Vught, B. P. Scicluna, A. J. Hoogendijk, A. H. Zwinderman, O. L. Cremer, M. J. Bonten, M. J. Schultz, N. P. Juffermans, W. J. Wiersinga, G. Eren, Y. Tekdos, M. Dogan, O. Acicbe, E. Kaya, O. Hergunsel, S. Alsolamy, G. Ghamdi, L. Alswaidan, S. Alharbi, F. Alenezi, Y. Arabi, J. Heaton, A. Boyce, L. Nolan, A. Dukoff-Gordon, A. Dean, T. Mann Ben Yehudah, C. Fleischmann, D. Thomas-Rueddel, C. Haas, U. Dennler, K. Reinhart, O. Suntornlohanakul, B. Khwannimit, F. Breckenridge, A. Puxty, P. Szturz, P. Folwarzcny, J. Svancara, R. Kula, P. Sevcik, L. Caneva, A. Casazza, E. Bellazzi, S. Marra, L. Pagani, M. Vetere, R. Vanzino, D. Ciprandi, R. Preda, R. Boschi, L. Carnevale, V. Lopez, M. Aguilar Arzapalo, L. Barradas, A. Escalante, J. Gongora, M. Cetina, B Adamik, D Jakubczyk, A Kübler, A. Radford, T. Lee, J. Singer, J. Boyd, D. Fineberg, M. Williams, J. Russell, E. Scarlatescu, G. Droc, S. Arama, M. Müller, M. Straat, S. S. Zeerleder, C. F. Fuchs, C. S. Scheer, S. W. Wauschkuhn, M. V. Vollmer, K. M. Meissner, S. K. Kuhn, K. H. Hahnenkamp, S. R. Rehberg, M. G. Gründling, S. Hamaguchi, E. Gómez-Sánchez, M. Heredia-Rodríguez, E. Álvarez-Fuente, M. Lorenzo-López, E. Gómez-Pesquera, M. Aragón-Camino, P. Liu-Zhu, A. Sánchez-López, A. Hernández-Lozano, M. T. Peláez-Jareño, E. Tamayo, D. O. Thomas-Rüddel, V. Adora, A. Kar, A. Chakraborty, S. Roy, A. Bandyopadhyay, M. Das, G. BenYehudah, M. Salim, N. Kumar, L. Arabi, T. Burger, P. Lephart, E. Toth-martin, C. Valencia, N. Hammami, S. Blot, J. L. Vincent, M. L. Lambert, J. Brunke, T. Riemann, I. Roschke, S. Nimitvilai, K. Jintanapramote, S. Jarupongprapa, D. Adukauskiene, D. Valanciene, G. Bose, V. Lostarakos, B. Carr, S. Khedher, A. Maaoui, A. Ezzamouri, M. Salem, J. Chen, D. R. Cranendonk, M. Day, G. Penrice, K. Roy, P. Robertson, G. Godbole, B. Jones, M. Booth, L. Donaldson, Y. Kawano, H. Ishikura, H. Al-Dorzi, M. Almutairi, B. Alhamadi, A. Crizaldo Toledo, R. Khan, B. Al Raiy, H. Talaie, J. A. Van Oers, A. Harts, E. Nieuwkoop, P. Vos, Y. Boussarsar, F. Boutouta, S. Kamoun, I. Mezghani, S. Koubaji, A. Ben Souissi, A. Riahi, M. S. Mebazaa, E. Giamarellos-Bourboulis, N. Tziolos, C. Routsi, C. Katsenos, I. Tsangaris, I. Pneumatikos, G. Vlachogiannis, V. Theodorou, A. Prekates, E. Antypa, V. Koulouras, N. Kapravelos, C. Gogos, E. Antoniadou, K. Mandragos, A. Armaganidis, A. R. Robles Caballero, B. Civantos, J. C. Figueira, J. López, A. Silva-Pinto, F. Ceia, A. Sarmento, L. Santos, G. Almekhlafi, Y. Sakr, S. Baharoon, A. Aldawood, A. Matroud, J. Alchin, S. Al Johani, H. Balkhy, S. Y. Yousif, B. O. Alotabi, A. S. Alsaawi, J. Ang, M. D. Curran, D. Enoch, V. Navapurkar, A. Morris, R. Sharvill, J. Astin, J. Patel, C. Kruger, J. O’Neal, H. Rhodes, J. Jancik, B. François, P. F. Laterre, P. Eggimann, A. Torres, M. Sánchez, P. F. Dequin, G. L. Bassi, J. Chastre, H. S. Jafri, M. Ben Romdhane, Z. Douira, M. Bousselmi, A. Vakalos, V. Avramidis, T. H. Craven, G. Wojcik, K. Kefala, J. McCoubrey, J. Reilly, R. Paterson, D. Inverarity, I. Laurenson, T. S. Walsh, S. Mongodi, B. Bouhemad, A. Orlando, A. Stella, G. Via, G. Iotti, A. Braschi, F. Mojoli, M. Haliloglu, B. Bilgili, U. Kasapoglu, I. Sayan, M. Süzer Aslan, A. Yalcin, I. Cinel, H. E. Ellis, K. Bauchmuller, D. Miller, A. Temple, C. 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Matauoka, T. Uejima, N. Morimura, A. Hagiwara, M. Takeda, O. Tarabrin, S. Shcherbakow, D. Gavrychenko, G. Mazurenko, V. Ivanova, O. Chystikov, C. Plourde, J. Lessard, J. Chauny, R. Daoust, L. Kropman, L. In het Panhuis, J. Konings, D. Huskens, E. Schurgers, M. Roest, B. De Laat, M. Lance, M. Durila, P. Lukas, M. Astraverkhava, J. Jonas, I. Budnik, B. Shenkman, H. Hayami, Y. Koide, T. Goto, R. Iqbal, Y. Alhamdi, N. Venugopal, S. Abrams, C. Downey, C. H. Toh, I. D. Welters, V. B. Bombay, J. M. Chauny, R. D. Daoust, J. L. Lessard, M. M. Marquis, J. P. Paquet, K. Siemens, D. Sangaran, B. J. Hunt, A. Durward, A. Nyman, I. A. Murdoch, S. M. Tibby, F. Ampatzidou, D. Moisidou, E. Dalampini, M. Nastou, E. Vasilarou, V. Kalaizi, H. Chatzikostenoglou, G. Drossos, S. Spadaro, A. Fogagnolo, T. Fiore, A. Schiavi, V. Fontana, F. Taccone, C. Volta, E. Chochliourou, E. Volakli, A. Violaki, E. Samkinidou, G. Evlavis, V. Panagiotidou, M. Sdougka, R. Mothukuri, C. Battle, K. Guy, J. Wijesuriya, S. 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Sbiti-Rohr, H. Na, S. Song, S. Lee, E. Jeong, K. Lee, E. Zoumpelouli, E. A Volakli, V. Chrysohoidou, K. Charisopoulou, E. Kotzapanagiotou, K. Manavidou, Z. Stathi, B. AlGhamdi, Q. Marashly, K. Zaza, M. Khurshid, Z. Ali, M. Malgapo, M. Jamil, A. Shafquat, M. Shoukri, M. Hijazi, F. A. Rocha, K. Ebecken, L. S. Rabello, M. F. Lima, R. Hatum, F. V. De Marco, A. Alves, J. E. Pinto, M. Godoy, P. E. Brasil, F. A. Bozza, J. I. Salluh, M. Soares, J. Krinsley, G. Kang, J. Perry, H. Hines, K. M. Wilkinson, C. Tordoff, B. Sloan, M. C. Bellamy, E. Moreira, F. Verga, M. Barbato, G. Burghi, M Soares, U. V. Silva, A. P. Torelly, J. M. Kahn, D. C. Angus, M. F. Knibel, R. Marshall, T. Gilpin, D. Mota, B. Loureiro, J. Dias, O. Afonso, F. Coelho, A. Martins, F. Faria, H. Al Orainni, F. AlEid, H. Tlaygeh, A. Itani, A. Hejazi, J. Messika, J. D. Ricard, S. Guillo, B. Pasquet, E. Dubief, F. Tubach, K. James, P. Temblett, L. Davies, C. Lynch, S. Pereira, S. Cavaco, J. Fernandes, I. Moreira, E. Almeida, F. Seabra Pereira, M. Malheiro, F. Cardoso, I. Aragão, T. Cardoso, M. Fister, P. Muraray Govind, N. Brahmananda Reddy, R. Pratheema, E. D. Arul, J. Devachandran, N. Chin-Yee, G. D’Egidio, K. Thavorn, K. Kyeremanteng, A. G. Murchison, K. Swalwell, J. Mandeville, D. Stott, I. Guerreiro, C. Goossens, M. B. Marques, S. Derde, S. Vander Perre, T. Dufour, S. E. Thiessen, F. Güiza, T. Janssens, G. Hermans, I. Vanhorebeek, K. De Bock, G. Van den Berghe, L. Langouche, B. Miles, S. Madden, M. Weiler, P. Marques, C. Rodrigues, M. Boeira, K. Brenner, C. Leães, A. Machado, R. Townsend, J. Andrade, R. Kishore, C. Fenlon, T. Fiks, A. Ruijter, M. Te Raa, P. Spronk, P. Docherty, J. Dickson, E. Moltchanova, C. Scarrot, T. Hall, W. C. Ngu, J. M. Jack, A. Pavli, X. Gee, E. Akin Korhan, M. Shirazy, A. Fayed, S. Gupta, A. Kaushal, S. Dewan, A. Varma, E. Ghosh, L. Yang, L. Eshelman, B. Lord, E. Carlson, R. Broderick, J. Ramos, D. Forte, F. Yang, J. Feeney, K. Wilkinson, K. Shuker, M. Faulds, D. Bryden, L. England, K Shuker, A Tridente, M Faulds, A Matheson, J. Gaynor, D Bryden, S South Yorkshire Hospitals Researc ᅟ, B. Peroni, R. Daglius-Dias, L. Miranda, C. Cohen, C. Carvalho, I. Velasco, J. M. Kelly, A. Neill, G. Rubenfeld, N. Masson, A. Min, E. Boezeman, J. Hofhuis, A. Hovingh, R. De Vries, G. Cabral-Campello, M. Van Mol, M. Nijkamp, E. Kompanje, P. Ostrowski, K. Kiss, B. Köves, V. Csernus, Z. Molnár, Y. Hoydonckx, S. Vanwing, V. Medo, R. Galvez, J. P. Miranda, C. Stone, T. Wigmore, Y. Arunan, A. Wheeler, Y. Wong, C. Poi, C. Gu, P. Molmy, N. Van Grunderbeeck, O. Nigeon, M. Lemyze, D. Thevenin, J. Mallat, M. Correa, R. T. Carvalho, A. Fernandez, C. McBride, E. Koonthalloor, C. Walsh, A. Webber, M. Ashe, K. Smith, E. A. Volakli, M. Dimitriadou, P. Mantzafleri, O. Vrani, A. Arbouti, T. Varsami, J. A. Bollen, T. C. Van Smaalen, W. C. De Jongh, M. M. Ten Hoopen, D. Ysebaert, L. W. Van Heurn, W. N. Van Mook, A. Roze des Ordons, P. Couillard, C. Doig, R. V. Van Keer, R. D. Deschepper, A. F. Francke, L. H. Huyghens, J. B. Bilsen, B. Nyamaizi, C. Dalrymple, A. Dobru, E. Marrinan, A. Ankuli, R. Struthers, R. Crawford, P. Mactavish, P. Morelli, M. Degiovanangelo, F. Lemos, V. MArtinez, J. Cabrera, A. Rutten, S. Van Ieperen, S. De Geer, M. Van Vugt, E. Der Kinderen, A. Giannini, G Miccinesi, T Marchesi, and E Prandi
Subjects: 0301 basic medicine, 03 medical and health sciences, medicine.medical_specialty, 030219 obstetrics & reproductive medicine, 030104 developmental biology, 0302 clinical medicine, business.industry, Intensive care, Emergency medicine, Medicine, Critical Care and Intensive Care Medicine, business
Published: 2016
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7. Poster Session 3: Friday 9 December 2011, 08:30-12:30 * Location: Poster Area

Author: C. Kenny, S. Adhya, R. Dworakowski, B. Brickham, P. Maccarthy, M. Monaghan, A. Guzzo, F. Innocenti, S. Vicidomini, D. Lazzeretti, S. Squarciotta, E. De Villa, C. Donnini, F. Bulletti, E. Guerrini, R. Pini, K. Bendjelid, J. Viale, S. Duperret, V. Piriou, D. Jacques, K. Shahgaldi, C. Silva, F. Pedro, L. Deister, L.-A. Brodin, A. Sahlen, A. Manouras, R. Winter, N. Berjeb, C. Cimadevilla, J. Dreyfus, C. Cueff, M. Malanca, A. Chiampan, A. Vahanian, D. Messika-Zeitoun, D. Muraru, D. Peluso, L. Dal Bianco, M. Beraldo, E. Solda', M. Tuveri, U. Cucchini, A. Al Mamary, L. Badano, S. Iliceto, I. Almuntaser, G. King, S. Norris, C. Daly, E. Ellis, R. Murphy, T. Erdei, M. Denes, A. Kardos, C. Foldesi, A. Temesvari, M. Lengyel, A. Bouzas Mosquera, F. Broullon, N. Alvarez-Garcia, J. Peteiro, G. Barge-Caballero, M. Lopez-Perez, A. Lopez-Sainz, A. Castro-Beiras, M. Luotolahti, H. Luotolahti, I. Kantola, J. Viikari, M. Andersen, M. Ersboell, J. Bro-Jeppesen, F. Gustafsson, L. Koeber, C. Hassager, J. Moller, D. Coisne, C. Diakov, F. Vallet, B. Lequeux, P. Blouin, L. Christiaens, R. Esposito, A. Santoro, V. Schiano Lomoriello, R. Raia, C. Santoro, G. De Simone, M. Galderisi, G. Abdula, W. Kosmala, H. Szczepanik-Osadnik, M. Przewlocka-Kosmala, A. Mysiak, T. O' Moore-Sullivan, T. Marwick, Y. T. Tan, F. Wenzelburger, F. Leyva, J. Sanderson, P. Pichler, B. Syeda, P. Hoefer, A. Zuckermann, T. Binder, M. Fijalkowski, A. Koprowski, R. Galaska, K. Blaut, K. Sworczak, A. Rynkiewicz, S. Lee, W. Kim, L. Jung, H. Yun, M. Song, J. Ko, E. A. Khalifa, P. Szymanski, M. Lipczynska, A. Klisieiwcz, P. Hoffman, C. Jorge, J. Silva Marques, S. Robalo Martins, C. Calisto, M. Mieiro, S. Vieira, M. Correia, J. Carvalho De Sousa, A. Almeida, A. Nunes Diogo, C. Park, K. March, T. Tillin, J. Mayet, N. Chaturvedi, A. Hughes, V. Di Bello, C. Giannini, M. Delle Donne, F. De Sanctis, P. Spontoni, C. Cucco, A. Corciu, C. Grigoratos, F. Bogazzi, A. Balbarini, O. Enescu, B. Suran, M. Florescu, M. Cinteza, D. Vinereanu, Y. Higuchi, K. Iwakura, A. Okamura, M. Date, K. Fujii, N. Cortez-Dias, D. Silva, P. Carrilho-Ferreira, A. Magalhaes, S. Ribeiro, S. Goncalves, M. Fiuza, F. Pinto, R. Placido, A. Bordalo, P. Grzywocz, K. Mizia-Stec, J. Chudek, Z. Gasior, A. M. Maceira Gonzalez, J. Cosin Sales, E. Dalli, B. Igual, J. Diago, J. Aguilar, J. Ruvira, S. Cimino, G. Pedrizzetti, G. Tonti, E. Canali, V. Petronilli, F. Boccalini, A. Mattatelli, Y. Hiramoto, C. Iacoboni, L. Agati, D. Trifunovic, M. Ostojic, B. Vujisic-Tesic, M. Petrovic, I. Nedeljkovic, M. Banovic, M. Boricic-Kostic, G. Draganic, M. Tesic, C. Gavina, R. Lopes, A. Lourenco, J. Almeida, J. Rodrigues, P. Pinho, J. Zamorano, A. Leite-Moreira, F. Rocha-Goncalves, M.-A. Clavel, R. Capoulade, J. Dumesnil, P. Mathieu, J.-P. Despres, P. Pibarot, S. Bull, A. Pitcher, D. Augustine, J. D'arcy, T. Karamitsos, A. Rai, B. Prendergast, H. Becher, S. Neubauer, S. Myerson, J. Magne, E. Donal, L. Davin, K. O'connor, C. Pirlet, M. Rosca, C. Szymanski, B. Cosyns, L. Pierard, P. Lancellotti, A. Calin, B. Popescu, C. Beladan, R. Enache, L. Lupascu, C. Sandu, C. Ginghina, V. Kamperidis, S. Hadjimiltiadis, G. Sianos, K. Anastasiadis, V. Grosomanidis, G. Efthimiadis, H. Karvounis, G. Parharidis, I. Styliadis, C. Gonzalez Canovas, C. Munoz-Esparza, J. Bonaque Gonzalez, A. Fernandez, M. Salar Alcaraz, D. Saura Espin, E. Pinar Bermudez, M. Oliva-Sandoval, G. De La Morena Valenzuela, M. Valdes Chavarri, E. Brochet, L. Lepage, D. Attias, D. Detaint, D. Himbert, B. Iung, B. Pirat, S. Little, S. Chang, L. Tiller, R. Kumar, W. Zoghbi, A. P.-W. Lee, M. Hsiung, S. Wan, R. Wong, F. Luo, F. Fang, J. Xie, M. Underwood, J. Sun, C. Yu, R. Jansen, W. Tietge, K. Sijbrandij, M. Cramer, L. De Heer, J. Kluin, S. A. J. Chamuleau, T. Oliveras Vila, E. Ferrer Sistach, L. Delgado Ramis, J. Lopez Ayerbe, N. Vallejo Camazon, F. Gual Capllonch, C. Garcia Alonso, A. Teis Soley, X. Ruyra Baliarda, A. Bayes Genis, S. Negrea, C. Alexandrescu, F. Bourlon, F. Civaia, G. Dreyfus, S. Paetzold, O. Luha, R. Hoedl, G. Stoschitzky, K. Pfeiffer, D. Zweiker, B. Pieske, R. Maier, T. Sevilla, A. Revilla, J. Lopez, I. Vilacosta, R. Arnold, I. Gomez, J. San Roman, G. Nikcevic, A. Djordjevic Dikic, S. Djordjevic, S. Raspopovic, V. Jovanovic, B. Kircanski, S. Pavlovic, G. Milasinovic, I. Ruiz-Zamora, F. Cabrera Bueno, M. Molina, J. Fernandez-Pastor, J. Pena, A. Linde, A. Barrera, J. Alzueta, C. Bremont, A. Bensaid, H. Alonso, O. Zaghden, J. Nahum, J. Dubois-Rande, P. Gueret, P. Lim, S.-P. Lee, K. Park, H.-R. Kim, J.-H. Lee, H.-S. Ahn, J.-H. Kim, H.-K. Kim, Y.-J. Kim, D.-W. Sohn, M. Niemann, S. Herrmann, K. Hu, D. Liu, M. Beer, G. Ertl, C. Wanner, T. Takenaka, C. Tei, F. Weidemann, H. Madeira, M. Mendes Pedro, D. Brito, R. Ippolito, D. De Palma, S. Gati, D. Oxborough, M. Reed, A. Zaidi, S. Ghani, N. Sheikh, M. Papadakis, S. Sharma, V. Chow, A. Ng, T. Pasqualon, W. Zhao, D. Hanzek, T. Chung, T. Yeoh, L. Kritharides, L. Magda, D. Mihalcea, D. Jinga, R. Mincu, E. Ferrazzi, G. Segato, F. Folino, G. Famoso, M. Senzolo, R. Bellu, F. Corbetti, F. Tona, O. Azevedo, I. Quelhas, J. Guardado, M. Fernandes, V. Pereira, R. Medeiros, P. Sousa, W. Santos, S. Pereira, N. Marques, J. Mimoso, V. Marques, I. Jesus, L. Rustad, K. Nytroen, L. Gullestad, B. Amundsen, S. Aakhus, K. Linhartova, G. Sterbakova, J. Necas, S. Kovalova, R. Cerbak, N. Nelassov, N. Korotkijan, A. Shishkina, B. Gagieva, M. Nagaplev, O. Eroshenko, M. Morgunov, S. Parmon, S. Velthuis, M. Van Gent, M. Post, C. Westermann, J. Mager, R. Snijder, S. P. Koyalakonda, M. Anderson, M. Burgess, L. Bergenzaun, M. Chew, H. Ohlin, G. F. Gjerdalen, J. Hisdal, E. Solberg, T. Andersen, Z. Radunovic, K. Steine, T. Rutz, A. Kuehn, K. Petzuch, M. Pekala, J. Elmenhorst, S. Fratz, J. Mueller, A. Hager, J. Hess, M. Vogt, D. Van Der Linde, I. Van De Laar, M. Wessels, J. Bekkers, A. Moelker, H. Tanghe, F. Van Kooten, R. Oldenburg, A. Bertoli-Avella, J. Roos-Hesselink, A. Cresti, L. Fontani, P. Calabria, E. Capati, S. Severi, M. Lynch, S. Saraf, B. Sandler, S. Yoon, S. Kim, C. Ko, S. Ryu, Y. Byun, H. Seo, Q. Ciampi, F. Rigo, L. Pratali, S. Gherardi, B. Villari, E. Picano, R. Sicari, J. Celutkiene, D. Zakarkaite, V. Skorniakov, V. Zvironaite, V. Grabauskiene, J. Sinicyna, G. Gruodyte, K. Janonyte, A. Laucevicius, J. O'driscoll, K. Schmid, A. Marciniak, A. Saha, S. Gupta, R. Smith, R. Sharma, N. Alvarez Garcia, O. Prada, A. Rodriguez Vilela, G. Barge Caballero, M. Lopez Perez, A. Lopez Sainz, A. Castro Beiras, J. Kochanowski, P. Scislo, R. Piatkowski, M. Grabowski, M. Marchel, M. Roik, D. Kosior, G. Opolski, C. M. Van De Heyning, H. Mahjoub, H. Clausen, C. Basaggianis, J. Newton, A. Del Pasqua, A. Carotti, D. Di Carlo, E. Cetrano, A. Toscano, R. Iacobelli, C. Esposito, M. Chinali, G. Pongiglione, G. Rinelli, M. Larsson, A. Bjallmark, K. Caidahl, L. Brodin, H. Gao, M. Lugiez, C. Guivier, R. Rieu, J. D'hooge, G. Hang, C. Guerin, M. Menard, J.-U. Voigt, J. Dungu, G. Campos, R. Jaffarulla, S. Gomes-Pereira, N. Sutaria, C. Baker, P. Nihoyannopoulos, M. Bellamy, D. Harries, N. Walker, P. Pearson, J. Reiken, J. Batteson, R. Kamdar, F. Murgatroyd, A. D'andrea, L. Riegler, R. Scarafile, E. Pezzullo, G. Salerno, E. Bossone, G. Limongelli, M. Russo, G. Pacileo, R. Calabro', Y. Kang, J. Cui, H. Chen, C. Pan, X. Shu, A. Kiotsekoglou, S. Saha, R. Toole, S. Govind, A. Gopal, F. Crispi, B. Bijnens, E. Sepulveda-Swatson, J. Rojas-Benavente, J. Dominguez, M. Illa, E. Eixarch, M. Sitges, E. Gratacos, C. Prinz, R. Faludi, A. Walker, M. Amzulescu, T. Uejima, A. Fraser, J. Voigt, M. Esmaeilzadeh, M. Maleki, A. Amin, F. Vakilian, F. Noohi, Z. Ojaghi Haghighi, P. Nakhostin Davari, H. Bakhshandeh Abkenar, R. Rimbas, R. Dulgheru, A. Margulescu, M. D' Asaro, C. Mizzon, F. Parisi, B.-C. Jung, B.-Y. Lee, H.-J. Kang, M. Kim, Y. Kim, D. Cho, S. Park, S. Hong, D. Lim, W. Shim, H. Bellsham-Revell, S. Tibby, A. J. Bell, O. I. Miller, G. Greil, J. M. Simpson, R. A. Providencia, J. Trigo, A. Botelho, P. Gomes, L. Seca, S. Barra, A. Faustino, G. Costa, N. Quintal, A. Leitao-Marques, E. Nestaas, A. Stoylen, D. Fugelseth, C. Mornos, A. Ionac, L. Petrescu, D. Cozma, D. Dragulescu, A. Mornos, S. Pescariu, A. Fontana, M. Abbate, M. Cazzaniga, C. Giannattasio, G. Trocino, K. Laser, L. Faber, M. Fischer, H. Koerperich, D. Kececioglu, M. F. Elnoamany, A. Dawood, M. Elhabashy, Y. Khalil, N. Piriou, K. Warin-Fresse, M. Caza, G. Fau, D. Crochet, N. Xhabija, I. Allajbeu, E. Petrela, M. Heba, M. Barreiro Perez, M. Martin Fernandez, A. Renilla Gonzalez, J. Florez Munoz, O. Fernandez Cimadevilla, I. Alvarez Pichel, E. Velasco Alonso, D. Leon Duran, E. Benito Martin, S. Secades Gonzalez, L. Gargani, P. Pang, E. Davis, A. Schumacher, A. Silva Ferreira, N. Bettencourt, P. Matos, L. Oliveira, J. Cosin-Sales, M. Lopez Lereu, J. Monmeneu, J. Estornell, M. Tsverava, D. Tsverava, A. Varela, M. Salagianni, I. Galani, E. Andreakos, C. Davos, I. Ikonomidis, J. Lekakis, V. Tritakis, N. Kadoglou, J. Papadakis, P. Trivilou, S. Tzortzis, C. Koukoulis, I. Paraskevaidis, M. Anastasiou-Nana, G. Kim, H. Youn, P. Ibrahimi, G. Bajraktari, F. Jashari, A. Ahmeti, A. Poniku, E. Haliti, M. Henein, B. Pezo Nikolic, H. Jurin, D. Lovric, Z. Baricevic, I. Ivanac Vranesic, M. Lovric Bencic, A. Ernst, and J. Separovic Hanzevacki
Subjects: Novel technique, business.industry, Medicine, Radiology, Nuclear Medicine and imaging, Computer vision, Nanotechnology, General Medicine, Contrast (music), Artificial intelligence, Cardiology and Cardiovascular Medicine, business
Published: 2011
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8. Poster session V * Saturday 11 December 2010, 08:30-12:30

Author: Q. H. Pham, T. G. Von Lueder, S. K. Namtvedt, H. Rosjo, T. Omland, K. Steine, A. T. Timoteo, M. Mota Carmo, M. Simoes, L. M. Branco, R. C. Ferreira, R. Kato, J. Ito, T. Tahara, Y. Yokoyama, T. Ashikaga, Y. Satoh, J. O. Na, H. E. Hong, M. N. Kim, S. Y. Shin, C. U. Choi, E. J. Kim, S. W. Rha, C. G. Park, H. S. Seo, D. J. Oh, R. Ticulescu, S. Brigido, O. Vriz, L. Sparacino, B. A. Popescu, C. Ginghina, S. Carerj, G. L. Nicolosi, F. Antonini-Canterin, J. J. Onaindia Gandarias, A. Romero, E. Laraudogoitia, S. Velasco, O. Quintana, A. Cacicedo, I. Rodriguez, J. A. Alarcon, J. Gonzalez, I. Lekuona, A. Subinas, G. Abdula, L. H. Lund, R. Winter, L. Brodin, A. Sahlen, M. Masaki, Y. M. Cha, T. Yuasa, K. Dong, Y. X. Dong, S. V. Mankad, J. K. Oh, F. Vallet, B. Lequeux, C. Diakov, P. Sosner, L. Christiaens, D. Coisne, C. Kihara, K. Murata, Y. Wada, K. Uchida, T. Ueyama, S. Okuda, T. Susa, M. Matsuzaki, E. J. Cho, K. Y. Choi, B. J. Kwon, D. B. Kim, S. W. Jang, J. S. Cho, H. O. Jung, H. K. Jeon, H. J. Youn, J. H. Kim, M. Cikes, B. Bijnens, V. Velagic, T. Kopjar, D. Milicic, B. Biocina, H. Gasparovic, I. Almuntaser, A. Brown, B. Foley, N. Mulvihill, P. Crean, G. King, R. Murphy, Y. Takata, M. Taniguchi, S. Nobusada, M. Sugawara, N. Toh, K. Kusano, H. Itoh, E. Wellnhofer, C. Kriatselis, S. Nedios, J. H. Gerds-Li, E. Fleck, M. K. Poulsen, J. E. Henriksen, J. Dahl, A. Johansen, T. Haghfelt, P. F. Hoilund-Carlsen, H. Beck-Nielsen, J. E. Moller, R. Dankowski, M. Wierzchowiecki, M. Michalski, A. Nowicka, K. Szymanowska, A. Pajak, K. Poprawski, A. Szyszka, M. Kasner, D. Westermann, H. P. Schultheiss, C. Tschoepe, T. Watanabe, M. Iwai-Takano, A. Kobayashi, H. Machii, Y. Takeishi, B. P. Paelinck, P. L. Van Herck, J. M. Bosmans, C. J. Vrints, H. J. Lamb, A. Doltra, B. Vidal, E. Silva, S. Poyatos, L. Mont, A. Berruezo, A. Castel, J. M. Tolosana, J. Brugada, M. Sitges, M. Dencker, O. Bjorgell, J. Hlebowicz, Z. S. Szelenyi, G. Szenasi, M. Kiss, Z. Prohaszka, A. Patocs, I. Karadi, A. Vereckei, S. K. Saha, P. L. Anderson, S. Govind, M. Govindan, J. C. Moggridge, A. Kiotsekoglou, A. S. Gopal, B. B. Loegstrup, T. B. Christophersen, D. E. Hoefsten, J. E. Moeller, H. E. Boetker, K. Egstrup, M. Graefe, F. Q. Huang, R. S. Zhang, T. T. Le, R. S. Tan, R. Sattarzadeh Badkoubeh, A. Tavoosi, A. R. Elahian, O. Drapkina, V. I. Ivashkin, A. Fazakas, L. Pepo, O. Janosi, I. Kopitovic, A. Goncalves, P. Marcos-Alberca, C. Almeria, G. Feltes, E. Rodriguez, E. Garcia, R. Hernandez-Antolin, C. Macaya, J. Silva Cardoso, J. L. Zamorano, M. S. Navarro, M. Valentin, C. M. Banes, F. Rigo, E. Grolla, F. Tona, V. Cuaia, A. Moreo, L. Badano, A. Raviele, S. Iliceto, P. Tarzia, A. Sestito, R. Nerla, A. Di Monaco, F. Infusino, D. Matera, F. Greco, R. M. Tacchino, G. A. Lanza, F. Crea, A. Nemes, E. Balazs, K. S. Pinter, A. Egyed, M. Csanady, T. Forster, E. Holte, J. Vegsundvag, T. Hole, K. Hegbom, R. Wiseth, D. Sharif, A. Sharif-Rasslan, C. Shahla, A. Khalil, U. Rosenschein, A. Zagatina, N. Zhuravskaya, T. V. Tyurina, E. Tagliamonte, T. Cirillo, A. Coppola, U. Marinelli, C. Romano, G. Riccio, R. Citro, C. Astarita, N. Capuano, G. Quaranta, A. Desiderio, S. Frattini, P. Faggiano, V. Zilioli, E. Locantore, S. Longhi, F. Bellandi, G. Faden, M. Triggiani, L. Dei Cas, M. Dalsgaard, J. Kjaergaard, K. Iversen, C. Hassager, W. Dinh, W. N. Nickl, J. S. Smettan, T. K. Koehler, T. D. Scheffold, M. C. B. Coll Barroso, J. G. Guelker, R. F. Fueth, V. Kamperidis, S. Hadjimiltiades, G. Sianos, G. Efthimiadis, H. Karvounis, G. Parcharidis, I. H. Styliadis, M. S. Velasco Del Castillo, J. J. Onaindia, M. Telleria, H. G. Carstensen, C. Nordenberg, P. Sogaard, T. Fritz-Hansen, J. Bech, S. Galatius, J. S. Jensen, R. Mogelvang, P. E. Bartko, S. Graf, R. Rosenhek, I. G. Burwash, J. Bergler-Klein, M.-A. Clavel, H. Baumgartner, P. Pibarot, G. Mundigler, B. Kirilmaz, I. Eser, N. Tuzun, B. Komur, H. Dogan, A. Taskiran Comez, E. Ercan, M. Cusma-Piccione, C. Zito, G. Oreto, S. Piluso, S. Tripepi, L. Oreto, C. Longordo, L. Ciraci, G. Di Bella, R. Piatkowski, J. Kochanowski, P. Scislo, M. Grabowski, M. Marchel, M. Roik, D. Kosior, G. Opolski, L. Sknouril, M. Dorda, B. Holek, L. Gajdusek, J. Chovancik, M. Branny, M. Fiala, P. Szymanski, M. Lipczynska, A. Klisiewicz, P. Hoffman, N. Jander, J. Minners, G. Martin, W. Zeh, M. Allgeier, C. Gohlke-Baewolf, H. Gohlke, S. Nistri, M. C. Porciani, M. Attanasio, R. Abbate, G. F. Gensini, G. Pepe, R. F. Duncan, C. Piantadosi, A. J. Nelson, G. Wittert, B. Dundon, M. I. Worthley, S. G. Worthley, P. Jung, K. Berlinger, J. Rieber, H. Z. Sohn, P. Schneider, M. Leibig, A. Koenig, V. Klauss, L. Tomkiewicz-Pajak, J. Kolcz, M. Olszowska, M. Pieculewicz, P. Podolec, T. Przewlocki, E. Suchon, B. Sobien, P. Wilkolek, A. Ziembicka, M. Hlawaty, A. Van De Bruaene, H. Hermans, R. Buys, L. Vanhees, M. Delcroix, J.-U. Voigt, W. Budts, E. De Cillis, T. Acquaviva, D. Basile, A. S. Bortone, D. Kalimanovska-Ostric, T. Nastasovic, B. Vujisic-Tesic, I. Jovanovic, B. Milakovic, M. Dostanic, M. Stosic, A. Frogoudaki, K. Andreou, J. Parisis, E. Triantafyllidi, S. Gaitani, J. Paraskevaidis, M. Anastasiou-Nana, G. De Pasquale, A. Kuehn, K. Petzuch, J. Mueller, C. Meierhofer, S. Fratz, A. Hager, J. Hess, M. Vogt, C. H. Attenhofer Jost, J. A. Dearani, C. G. Scott, H. M. Burkhart, H. M. Connolly, A. Vitarelli, D. Battaglia, F. Caranci, V. Padella, G. Continanza, O. Dettori, L. Capotosto, M. Vitarelli, V. De Cicco, M. Cortez Morichetti, K. K. Mohanan Nair, B. Sasidaharan, A. Thajudeen, J. M. Tharakan, L. Mertens, N. Ahmad, P. K. Kantor, L. Grosse-Wortmann, M. K. Friedberg, Y. F. Bernard, M. A. Morel, V. Descotes-Genon, J. Jehl, N. Meneveau, F. Schiele, M. Kaldararova, I. Simkova, P. Tittel, J. Masura, O. Trojnarska, L. Szczepaniak, K. Mizia -Stec, A. Cieplucha, A. Bartczak, S. Grajek, A. Tykarski, Z. Gasior, D. Babovicvuksanovic, C. R. Bonnichsen, G. J. Morgan, C. Slorach, W. Hui, T. Sarkola, K. J. Lee, R. Chaturvedi, L. Benson, T. Bradley, M. E. Iancu, I. Ghiorghiu, M. Serban, I. Craciunescu, A. Hodo, J. Morgan, L. Roche, K. Lee, O. Milanesi, V. Favero, M. Padalino, R. Biffanti, A. Cerutti, N. Maschietto, E. Reffo, V. Vida, G. Stellin, O. Irtyuga, D. Gamazin, I. Voronkina, N. Tsoyi, E. Gudkova, O. Moiseeva, C. Aggeli, C. Kazazaki, I. Felekos, S. Lagoudakou, G. Roussakis, J. Skoumas, C. Pitsavos, C. Stefanadis, C. Cueff, N. Keenan, P. G. Steg, C. Cimadevilla, G. Ducrocq, A. Vahanian, D. Messika-Zeitoun, L. Petrella, A. M. Mazzola, C. V. Villani, R. G. Giancola, M. C. Ciocca, D. E. M. Di Eusanio, S. Nolan, A. Ionescu, T. R. Skaug, B. H. Amundsen, T. Hergum, H. Torp, B. O. Haugen, J. Lopez Aguilera, D. Mesa Rubio, M. Ruiz Ortiz, M. Delgado Ortega, E. Villanueva Fernandez, L. Cejudo Diaz Del Campo, F. Toledano Delgado, M. Leon Del Pino, E. Romo Pena, J. Suarez De Lezo Cruz-Conde, E. De Marco, A. Colucci, G. Comerci, F. A. Gabrielli, R. Natali, B. Garramone, M. Savino, M. Lotrionte, A. Sonaglioni, F. Loperfido, M. Zdravkovic, J. Perunicic, M. Krotin, M. Ristic, V. Vukomanovic, M. Zaja, S. Radovanovic, J. Saric, D. Zdravkovic, C. Cotrim, A. R. Almeida, R. Miranda, A. G. Almeida, E. Picano, M. Carrageta, A. D'andrea, R. Cocchia, L. Riegler, E. Golia, R. Scarafile, P. Caso, M. G. Russo, E. Bossone, R. Calabro', H. Noman, A. Adel, A. M. R. Elfaramawy, M. Abdelraouf, W. A. E. L. Elnaggar, E. Baligh, L. Sargento, D. Silva, S. Goncalves, S. Ribeiro, G. Vinhas Sousa, A. Almeida, M. Lopes, M. Rodriguez-Manero, L. Aguado Gil, P. Azcarate, P. Lloret Luna, A. Macias Gallego, S. A. R. A. Castano, M. Garcia, C. Pujol Salvador, J. Barba, P. Redondo, L. Tomasoni, S. Sitia, F. Atzeni, L. Gianturco, C. Ricci, P. Sarzi-Puttini, M. Turiel, V. De Gennaro Colonna, T. Uejima, J. Jaroch, C. Polombo, A. Hughes, D. Vinereanu, A. Evanvelista, G. Leftheriotis, A. G. Fraser, A. Lewczuk, B. Sobkowicz, A. Tomaszuk-Kazberuk, R. Sawicki, T. Hirnle, B. W. Michalski, D. Filipiak, J. D. Kasprzak, P. Lipiec, H. Dalen, O. C. Mjolstad, B. E. Klykken, T. Graven, M. Martensson, M. Olsson, L.-A. Brodin, R. Enache, E. Leiballi, A. Penhall, R. Perry, M. Altman, A. Sinhal, J. Bennetts, D. P. Chew, M. X. Joseph, L. H. Larsen, T. Kristensen, L. V. Kober, K. F. Kofoed, F. Moscoso Costa, R. Ribeiras, J. Brito, S. Boshoff, J. Neves, R. Teles, M. Canada, M. J. Andrade, R. Gouveia, A. Silva, A. Miskovic, T. P. Poerner, C. S. Stiller, B. G. Goebel, A. M. Moritz, L. Stefani, G. G. Galanti, M. Moraldo, C. Bergamini, P. A. Pabari, N. M. Dhutia, A. S. N. Malaweera, K. Willson, J. Davies, A. D. Hughes, X. Y. Xu, D. P. Francis, R. Jasaityte, B. Amundsen, D. Barbosa, D. Loeckx, G. Kiss, F. Orderud, V. Robesyn, P. Claus, J. D'hooge, T. Nao, T. Miura, K. Shams, S. Samir, R. Samir, M. El-Sayed, A. M. Anwar, Y. Nosir, A. Galal, H. Chamsi-Pasha, A. Ciobanu, R. Dulgheru, S. Bennett, A. De Luca, L. Toncelli, F. Cappelli, B. Cappelli, M. C. R. Vono, G. Galanti, Y. Zorman, M. S. Yilmazer, M. Akyildiz, T. Gurol, A. Aydin, B. Dagdeviren, and A. Kalangos
Subjects: medicine.medical_specialty, business.industry, Physical therapy, Medicine, Radiology, Nuclear Medicine and imaging, General Medicine, Session (computer science), Cardiology and Cardiovascular Medicine, business
Published: 2010
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9. Poster session II * Thursday 9 December 2010, 14:00-18:00

Author: P. A. Pabari, A. Kyriacou, M. Moraldo, B. Unsworth, R. Baruah, N. Sutaria, A. Hughes, J. Mayet, D. P. Francis, T. Uejima, K. Loboz, F. Antonini-Canterin, C. Polombo, S. Carerj, D. Vinereanu, A. Evangelista, G. Leftheriotis, A. G. Fraser, A. Kiotsekoglou, M. Govindan, S. C. Govind, S. K. Saha, A. J. Camm, P. M. Azcarate, S. Castano, M. Rodriguez-Manero, M. Arraiza, B. Levy, J. Barba, G. Rabago, G. Bastarrika, A. Nemes, R. Takacs, T. Varkonyi, H. Gavaller, I. Baczko, T. Forster, T. Wittmann, J. G. Papp, C. Lengyel, A. Varro, L. R. Tumasyan, K. G. Adamyan, O. Savu, T. Mieghem, P. Dekoninck, L. Gucciardo, R. Jurcut, S. Giusca, B. A. Popescu, C. Ginghina, J. Deprest, J. U. Voigt, M. Versiero, M. Galderisi, R. Esposito, A. Rapacciuolo, G. Esposito, R. Raia, T. Morgillo, F. Piscione, G. De Simone, M. A. Oraby, F. A. Maklady, E. M. Mohamed, A. Z. Eraki, D. Zaliaduonyte-Peksiene, E. Tamuleviciute, J. Janenaite, J. Marcinkeviciene, V. Mizariene, S. Bucyte, J. Vaskelyte, D. Trifunovic, I. Nedeljkovic, D. Popovic, M. Ostojic, B. Vujisic-Tesic, M. Petrovic, S. Stankovic, D. Sobic-Saranovic, M. Banovic, A. Dikic-Djordjevic, K. Savino, A. Lilli, E. Grikstaite, V. Giglio, E. Bordoni, G. Maragoni, C. Cavallini, G. Ambrosio, B. Jakovljevic, B. Beleslin, M. Nedeljkovic, O. Petrovic, S. Moral, J. Rodriguez-Palomares, M. Descalzo, G. Marti, V. Pineda, P. Mahia, L. Gutierrez, T. Gonzalez-Alujas, D. Garcia-Dorado, F. Schnell, E. Donal, C. Thebault, A. Bernard, H. Corbineau, H. Le Breton, J. Kochanowski, P. Scislo, R. Piatkowski, M. Roik, M. Marchel, D. Kosior, G. Opolski, A. M. Lesniak-Sobelga, E. Wicher-Muniak, M. Kostkiewicz, M. Olszowska, E. Suchon, P. Klimeczek, P. Banys, M. Pasowicz, W. Tracz, P. Podolec, A. Laynez, D. E. Hoefsten, B. B. Loegstrup, B. Norager, J. E. Moller, A. Flyvbjerg, K. Egstrup, W. Streb, M. Szulik, J. Nowak, E. Markowicz-Pawlus, A. Duszanska, A. Sedkowska, Z. Kalarus, T. Kukulski, L. Spinelli, C. Morisco, E. Assante Di Panzillo, F. Buono, S. Crispo, B. Trimarco, A. A. Hawary, G. M. Nasr, M. M. Fawzy, L. Faber, W. Scholtz, J. Boergermann, M. Wiemer, G. Kleikamp, N. Bogunovic, Z. Dimitriadis, J. Gummert, D. Hering, D. Horstkotte, F. Luca', S. Gelsomino, R. Lorusso, S. Caciolli, R. Carella, G. Bille', G. De Cicco, V. Pazzagli, G. F. Gensini, A. Borowiec, R. Dabrowski, J. Janas, A. Kraska, B. Firek, I. Kowalik, H. Szwed, K. A. Marcus, C. L. De Korte, T. Feuth, J. M. Thijssen, L. Kapusta, J. Dahl, L. Videbaek, M. K. Poulsen, P. A. Pellikka, K. Veien, L. I. Andersen, T. Haghfelt, M. Haberka, K. Mizia - Stec, T. Adamczyk, M. Mizia, A. Chmiel, P. Pysz, M. Sosnowski, Z. Gasior, M. Trusz - Gluza, M. Tendera, T. Niklewski, K. Wilczek, P. Chodor, T. Podolecki, A. Frycz-Kurek, M. Zembala, S. Yurdakul, O. Yildirimturk, Y. Tayyareci, K. Memic, I. C. C. Demiroglu, S. Aytekin, C. J. Garcia Alonso, E. Ferrer Sistach, L. Delgado, J. Lopez Ayerbe, N. Vallejo Camazon, F. Gual Capllonch, M. Espriu Simon, X. Ruyra, A. Caballero Parrilla, A. Bayes Genis, L. Lecuyer, A. Berrebi, E. Florens, M. Noghin, C. Huerre, P. Achouh, R. Zegdi, J. N. Fabiani, B. De Chiara, A. Moreo, F. Musca, F. De Marco, E. Lobiati, O. Belli, F. Mauri, S. Klugmann, A. Caballero, N. Vallejo, A. Gonzalez Guardia, R. Nunez Aragon, C. Bosch, E. Ferrer, M. L. Pedro Botet, F. Gual, M. Cusma-Piccione, C. Zito, G. Oreto, R. Giuffre, M. C. Todaro, C. M. Barbaro, S. Lanteri, C. Longordo, J. Salvia, A. Bensaid, R. Gallet, E. Fougeres, P. Lim, J. Nahum, J. F. Deux, P. Gueret, E. Teiger, J. L. Dubois-Rande, J. L. Monin, F. Behramoglu, Z. Colakoglu, V. Aytekin, C. Demiroglu, L. Gargani, E. Poggianti, R. Bucalo, M. Rizzo, F. Agrusta, P. Landi, R. Sicari, E. Picano, A. Sutandar, B. B. Siswanto, I. Irmalita, G. Harimurti, S. Y. Hayashi, M. M. Nascimento, B. Lindholm, B. Lind, A. Seeberger, M. A. Pachaly, M. C. Riella, A. Bjallmark, L. A. Brodin, L. Poanta, M. Porojan, D. L. Dumitrascu, I. Ikonomidis, S. Tzortzis, J. Lekakis, D. T. Kremastinos, I. Paraskevaidis, I. Andreadou, M. Nikolaou, P. Katsibri, M. Anastasiou-Nana, A. M. Maceira Gonzalez, C. Ripoll, J. Cosin-Sales, B. Igual, J. Salazar, V. Belloch, J. Cosin-Aguilar, D. J. Pennell, M. Masaki, J. N. Pulido, T. Yuasa, S. Gillespie, B. Afessa, D. R. Brown, S. V. Mankad, J. K. Oh, A. L. Gurghean, A. M. Mihailescu, I. Tudor, C. Homentcovschi, M. Muraru, I. V. Bruckner, C. E. Correia, B. Rodrigues, D. Moreira, L. F. Santos, P. Gama, O. Dionisio, C. Cabral, O. Santos, T. Bombardini, S. Gherardi, G. Arpesella, S. Valente, I. Calamai, E. Pasanisi, S. Sansoni, P. Szymanski, P. Dobrowolski, M. Lipczynska, A. Klisiewicz, P. Hoffman, D. Stepowski, B. Kurtz, G. Grezis-Soulie, A. Savoure, F. Anselme, F. Bauer, J. Castillo, N. Herszkowicz, C. Ferreira, A. Goscinska, K. Mizia-Stec, W. Poborski, O. Azevedo, I. Quelhas, J. Guardado, M. Fernandes, C. S. Miranda, P. Gaspar, A. Lourenco, R. Medeiros, J. Almeida, S. L Bennani, V. Algalarrondo, S. Dinanian, J. Guiader, C. Juin, D. Adams, M. S. Slama, J. J. Onaindia, O. Quintana, S. Velasco, E. Astigarraga, A. Cacicedo, J. Gonzalez, I. Rodriguez, M. Sadaba, M. Eneriz, E. Laraudogoitia Zaldumbide, I. Nunez-Gil, M. Luaces, J. Zamorano, J. C. Garcia Rubira, D. Vivas, B. Ibanez, P. Marcos Alberca, C. Fernandez Golfin, J. Alonso, C. Macaya, J. Silva Marques, A. G. Almeida, V. Carvalho, C. Jorge, D. Silva, M. Gato Varela, S. Martins, D. Brito, M. G. Lopes, E. Tripodi, B. Miserrafiti, V. Montemurro, R. Scali, P. Tripodi, A. Winkler, A. Madej, I. Hausmanowa-Petrusewicz, M. Fijalkowski, A. Koprowski, M. Jaguszewski, R. Galaska, M. Taszner, A. Rynkiewicz, R. Citro, F. Rigo, G. Provenza, Q. Ciampi, M. M. Patella, A. D'andrea, O. Vriz, C. Astarita, E. Bossone, F. Heggemann, T. H. Walter, T. H. Kaelsch, T. Sueselbeck, T. H. Papavassiliu, M. Borggrefe, D. Haghi, T. Monk-Hansen, C. Have Dall, S. Bisgaard Christensen, M. Snoer, F. Gustafsson, H. Rasmusen, E. Prescott, G. Finocchiaro, B. Pinamonti, M. Merlo, G. Barbati, A. Di Lenarda, R. Bussani, G. Sinagra, T. Butz, C. N. Lang, A. Meissner, G. Plehn, H. Yeni, C. Langer, H. J. Trappe, X. Gu, X. Y. Gu, Y. H. He, Z. A. Li, J. C. Han, J. Chen, P. Gaudron, M. Niemann, S. Herrmann, K. Hu, B. Bijnens, H. Hillenbrand, M. Beer, G. Ertl, F. Weidemann, A. Mazzone, M. Mariani, I. Foffa, A. Vianello, S. Del Ry, S. Bevilacqua, M. G. Andreassi, M. Glauber, S. Berti, M. Grabowski, M. Postula, A. Dragulescu, G. Van Arsdell, O. Al-Radi, C. Caldarone, L. Mertens, K. J. Lee, R. P. Casula, H. Yadav, A. Cherian, A. D. Hughes, A. Vitarelli, S. D'orazio, B. L. Nguyen, G. Iorio, D. Battaglia, F. Caranci, V. Padella, L. Capotosto, L. Alessandroni, F. Barilla, C. Cardin, S. Hascoet, M. Saudron, G. Caudron, B. Arnaudis, P. Acar, M. M. Sun, X. H. Shu, C. Z. Pan, X. Y. Fang, D. H. Kong, F. Fang, Q. Zhang, Y. S. Chan, J. M. Xie, W. K. Yip, Y. Y. Lam, J. E. Sanderson, C. M. Yu, M. Rosca, K. O' Connor, G. Romano, J. Magne, A. Calin, D. Muraru, L. Pierard, P. Lancellotti, A. Roushdy, I. Elfiky, G. El Shahid, A. Elfiky, M. El Sayed, K. Wierzbowska-Drabik, L. Chrzanowski, A. Kapusta, E. Plonska-Goscinak, M. Krzeminska-Pakula, M. Kurpesa, T. Rechcinski, E. Trzos, J. D. Kasprzak, M. K. Ersboll, N. Valeur, U. M. Mogensen, M. Andersen, C. Hassager, P. Sogaard, L. V. Kober, M. Kloeckner, D. Hayat, C. Dussault, N. Lellouche, N. Elbaz, A. Demopoulos, G. Hatzigeorgiou, E. Leontiades, A. Motsi, G. Karatasakis, G. Athanassopoulos, P. Zycinski, J. Kasprzak, M. C. Vazquez Alvarez, C. Medrano Lopez, M. Camino Lopez, S. Granja, J. L. Zunzunegui Martinez, E. Maroto Alvaro, W.-C. Tsai, J.-Y. Chen, Y.-W. Liu, C.-C. Lin, L.-M. Tsai, D. C. Gomes, S. Robalo Martins, M. R. Gois, S. Ribeiro, A. Nunes Diogo, P. Sengupta, G. Di Bella, G. Caracciolo, S. Lentini, E. Kinova, N. Zlatareva, A. Goudev, N. Papagiannis, M. Mpouki, A. Papagianni, M. Vorria, G. Mpenetos, D. Lytra, E. Papadopoulou, P. Sgourakis, J. Malakos, J. Kyriazis, V. Kodali, R. Toole, A. S. Gopal, J. Celutkiene, A. Rudys, V. Grabauskiene, S. Glaveckaite, E. Sadauskiene, Z. Lileikiene, N. Bickauskaite, E. Ciburiene, V. Skorniakov, A. Laucevicius, C. H. Attenhofer Jost, M. Pfyffer, R. Lindquist, J. L. F. Santos, O. R. C. Coelho, C. M. Mady, M. H. P. Picard, V. M. C. Salemi, L. Funk, M. W. Prull, J.-Y. Shih, Y.-Y. Huang, K. O'connor, M. Moonen, L. A. Pierard, D. C. Cozma, C. Mornos, A. Ionac, L. Petrescu, D. Dragulescu, R. Dan, I. Popescu, S. I. Dragulescu, T. G. Von Lueder, A. Hodt, G. F. Gjerdalen, T. E. Andersen, E. E. Solberg, K. Steine, T. Van Mieghem, M. Rostek, W. Pikto-Pietkiewicz, M. Dluzniewski, A. Antoniewicz, S. Poletajew, A. Borowka, T. Pasierski, S. K. Malyutina, M. Ryabikov, J. Ragino, A. Ryabikov, S. Sitia, L. Tomasoni, F. Atzeni, L. Gianturco, P. Sarzi-Puttini, V. De Gennaro Colonna, M. Turiel, F. R. Gutierrez, G. Lefhtheriotis, R. T. Hurst, M. R. Nelson, F. Mookadam, V. Thota, U. Emani, M. Al Harthi, J. Stepanek, S. Cha, S. J. Lester, E. M. M. Ho, L. Hemeryck, M. Hall, K. Scott, K. Bennett, A. Mahmud, C. Daly, G. King, R. T. Murphy, A. S. Brown, A. J. Teske, J. D'Hooge, P. Claus, F. Rademakers, L. Santos, N. Cortez-Dias, S. Goncalves, M. Almeida Ribeiro, A. Bordalo E Sa, C. Magnino, P. Marcos-Alberca, A. Milan, C. Almeria, V. Caniadas, J. L. Rodrigo, L. Perez De Isla, J. L. Zamorano, U. Gustafsson, M. Larsson, P. Lindqvist, L. Brodin, A. Waldenstrom, B. Roosens, S. Hernot, S. Droogmans, G. Van Camp, T. Lahoutte, B. Cosyns, C. M. Rao, D. Aguglia, G. Casciola, C. Imbesi, A. Marvelli, M. Sgro, D. Benedetto, R. Tripepi, C. Zoccali, F. A. Benedetto, L. P. Badano, M. Cardillo, L. Del Mestre, P. Gianfagna, A. Proclemer, H. D. Tschernich, B. Mora, E. Base, U. Weber, J. Dumfarth, C. Mukherjee, H. S. Skaltsiotis, A. K. Kaladaridis, D. B. Bramos, G. K. Kottis, A. A. Antoniou, I. A. Agrios, D. T. Takos, N. V. Vasiladiotis, K. P. Pamboucas, S. T. T. Toumanidis, A. Shim, P. Lipec, B. Michalski, B. Wozniakowski, L. Stefanczyk, A. Rotkiewicz, M. Cameli, M. Lisi, M. Padeletti, E. Bigio, S. Bernazzali, C. Tsoulpas, M. Maccherini, M. Henein, S. Mondillo, I. Garcia Lunar, S. Mingo Santos, V. Monivas Palomero, C. Mitroi, P. Beltran Correas, L. Ruiz Bautista, A. Muniz Lozano, M. Gonzalez Gonzalez, B. Stegemann, K. Willson, R. Zeppellini, A. Iavernaro, M. Zadro, M. Carasi, R. De Domenico, T. Rigo, E. Artuso, G. Erente, A. Ramondo, T. T. Le, F. Q. Huang, Y. Gu, and R. S. Tan
Subjects: Cardiac function curve, medicine.medical_specialty, medicine.anatomical_structure, business.industry, Ventricle, Internal medicine, medicine, Cardiology, Radiology, Nuclear Medicine and imaging, General Medicine, Cardiology and Cardiovascular Medicine, Rotation, business
Published: 2010
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10. Poster Session 3The imaging examination and quality assessmentP626Value of mitral and tricuspid annular displacement to assess the interventricular systolic relationship in severe aortic valve stenosis : a Pilot studyP627Follow-up echocardiography in asymptomatic valve disease: assessing the potential economic impact of the European and American guidelines in a dedicated valve clinic, compared to standard care.P628The tricuspid valve: identification of optimal view for assessing for prolapseP629Right atrial volume by two-dimensional echocardiography in healthy subjectsP630Disturbance of inter and intra atrial conduction assessed by tissue doppler imaging in patients with medicaly controlled hypertension and prehypertension.P631Liver stiffness by shear wave elastography, new noninvasive and quantitative tool for acute variation estimation of central venous pressure in real-time?P632Weak atrial kick contribution is associated with a risk for heart failure decompensationP633Usefulness of wave intensity analysis in predicting the response to cardiac resynchronization therapyP634Early subclinical left ventricular systolic and diastolic dysfunction in gestational hypertension and preeclampsiaP635Clinical comparison of three different echocardiographic methods for left ventricular ejection fraction and LV end diastolic volume measurementP636Assessment of right ventricular-arterial coupling parameters by 3D echocardiography in patients with pulmonary hypertension receiving specific vasodilator therapyP637Prediction of right ventricular failure after left ventricular assist device implant: assessing usefulness of standard and strain echocardiographyP638Kinematic analysis of diastolic function using the novel freely available software Echo E-waves - feasibility and reproducibilityP639Evaluation of coronary flow velocity by Doppler echocardiography in the treatment of hypertension with the ARB: correlation to the histological cardiac fibrosisP640The clinical significance of limited apical ischaemia and the prognostic value of stress echocardiography - A contemporary study from a high volume centerP641Effects of intermediate stenosis of left anterior descending coronary artery on survival in patients with chronic total occlusion of right coronary arteryP642Left ventricular remodeling after a first myocardial infarction in patients with preserved ejection fraction at dischargeP643Left atrial size and acute coronary syndromes. Let is make simple.P644Influence of STEMI reperfusion strategy on systolic and diastolic functionP645Aortic valve resistance risk-stratifies low-gradient severe aortic stenosisP646Does permanent pacemaker implantation complicate the prognosis of patients after transcatheter aortic valve implantation?P647Influence of metabolic syndrome and diabetes on progression of calcific aortic valve stenosis - The COFRASA - GENERAC StudyP648Low referral for aortic valve replacement accounts for worse long-term outcome in low versus high gradient severe aortic stenosis with preserved ejection fractionP649The impact of right ventricular function from aortic valve replacement: A randomised study comparing minimally invasive aortic valve surgery and conventional open heart surgery

Author: N. Hashemi, YJ. Mo, A. Testuz, M. D'angelo, H. Nishikawa, J. Nieto Tolosa, L. Reis, C. Volpi, A. Djordjevic-Dikic, A. Papachristidis, C. Wei-Ting, M. Sundqvist, DB. Diego Bellavia, E. Popa, N. Benyounes, N. Patrascu, K. Niki, L. Takahashi, O. Villemain, D. Djikic, F. Ferrara, NK. Preston, DNS Senaratne, T. Ota, K. Toyota, K. Nagamine, Y. Koide, T. Nomura, J. Kurata, Y. Murakami, Y. Kozuka, C. Ohshiro, K. Thomas, C. Townsend, S. Wheeler, I. Jacobson, A. Elkington, K. Balkhausen, S. Bull, L. Ring, L. Gargani, L. Carannante, V. Russo, M. D'alto, AM. Marra, A. Cittadini, A. D'andrea, O. Vriz, E. Bossone, N. Mujovic, B. Dejanovic, V. Peric, M. Marinkovic, N. Jankovic, B. Orbovic, D. Simic, F. Sitefane, M. Pernot, G. Malekzadeh-Milani, J. Baranger, D. Bonnet, Y. Boudjemline, T. Uejima, H. Semba, H. Sawada, T. Yamashita, M. Sugawara, H. Kayanuma, K. Inoue, M. Yagawa, I. Takamisawa, J. Umemura, T. Yoshikawa, H. Tomoike, DJ. Mihalcea, S. Mihaila, L. Lungeanu, LF. Trasca, R. Bruja, MS. Neagu, S. Albu, M. Cirstoiu, D. Vinereanu, C. Van Der Vynckt, O. Gout, A. Cohen, R. Enache, R. Jurcut, IM. Coman, R. Badea, P. Platon, A. Calin, CC. Beladan, M. Rosca, C. Ginghina, BA. Popescu, SD. Sonia Dell'oglio, AI. Attilio Iacovoni, CF. Calogero Falletta, GR. Giuseppe Romano, SS. Sergio Sciacca, LS. Lissa Sugeng, JM. Joseph Maalouf, MP. Michele Pilato, MS. Michele Senni, CS. Cesare Scardulla, FC. Francesco Clemenza, K. Salman, P. Tornvall, M. Ugander, ZC. Chen, JJ. Wang, S. Fisch, RL. Liao, D. Roper, D. Casar Demarco, M. Papitsas, I. Tsironis, J. Byrne, K. Alfakih, MJ. Monaghan, N. Boskovic, I. Rakocevic, V. Giga, M. Tesic, J. Stepanovic, I. Nedeljkovic, S. Aleksandric, J. Kostic, B. Beleslin, M. Altman, MS. Annabi, L. Abouchakra, U. Cucchini, D. Muraru, LP. Badano, L. Ernande, G. Derumeaux, R. Teixeira, A. Fernandes, I. Almeida, P. Dinis, M. Madeira, J. Ribeiro, L. Puga, J. Nascimento, L. Goncalves, FJ. Cambronero Sanchez, E. Pinar Bermudez, JR. Gimeno Blanes, G. De La Morena Valenzuela, T. Lopez Fernandez, FJ. Irazusta Cordoba, SO. Rosillo Rodriguez, FJ. Dominguez Melcon, P. Meras Colunga, D. Gemma, R. Moreno Gomez, M. Moreno Yanguela, JL. Lopez Sendon, V. Nguyen, T. Mathieu, C. Kerneis, C. Cimadevilla, N. Kubota, I. Codogno, S. Tubiana, C. Estrellat, A. Vahanian, D. Messika-Zeitoun, T. Ondrus, G. Van Camp, G. Di Gioia, E. Barbato, J. Bartunek, M. Penicka, J. Johnsson, A. Gomez, M. Alam, and R. Winter
Subjects: Pathology, medicine.medical_specialty, business.industry, General Medicine, Aneurysm dissecting, medicine.artery, Ascending aorta, Medicine, Thoracic aorta, Radiology, Nuclear Medicine and imaging, Gene polymorphism, Cardiology and Cardiovascular Medicine, business, Fibrillin
Published: 2016
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11. P336 Outcome of sentinel node biopsy after neoadjuvant chemotherapy in CN0 breast cancer

Author: Y. Kojima, Koichiro Tsugawa, H. Kawamoto, T. Uejima, T. Nishikawa, and R. Hayami
Subjects: Oncology, medicine.medical_specialty, Chemotherapy, medicine.diagnostic_test, business.industry, medicine.medical_treatment, General Medicine, Sentinel node, medicine.disease, Outcome (game theory), Breast cancer, Internal medicine, Biopsy, medicine, Surgery, business
Published: 2015
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12. General pediatric emergencies. Acute pulmonary edema

Author: T, Uejima
Subjects: Emergency Medical Services, Acute Disease, Humans, Pulmonary Edema, Child
Abstract: This article focuses on three types of acute pulmonary edema in children: negative-pressure pulmonary edema, neurogenic pulmonary edema, and cardiogenic pulmonary edema.
Published: 2001

13. Intramuscular rapacuronium in infants and children: a comparative multicenter study to confirm the efficacy and safety of the age-related tracheal intubating doses of intramuscular rapacuronium (ORG 9487) in two groups of pediatric subjects

Author: W T, Denman, R F, Kaplan, N G, Goudsouzian, T, Uejima, S L, Barcelona, C J, Cote, B, Ginsberg, and R S, Hannallah
Subjects: Male, Vecuronium Bromide, Child, Preschool, Intubation, Intratracheal, Humans, Infant, Female, Anesthesia, Inhalation, Halothane, Injections, Intramuscular, Neuromuscular Nondepolarizing Agents
Abstract: This multicenter, assessor, blinded, randomized study was conducted to confirm and extend a pilot study in which intramuscular rapacuronium was given to infants and children to confirm efficacy and to evaluate tracheal intubating conditions.Ninety-six pediatric patients were studied in two groups: infants aged 1 to 12 months (n = 46) and children aged 1 to 3 yr (n = 50). Infants received 2.8 mg/kg and children 4.8 mg/kg of intramuscular rapacuronium during 1 minimum alveolar concentration halothane anesthesia. These two groups were studied in three subgroups, depending on the time (1.5, 3, or 4 min) at which tracheal intubation was attempted after the administration of intramuscular rapacuronium into the deltoid muscle. Neuromuscular data collected included onset time, duration of action, and recovery data during train-of-four stimulation at 0.1 Hz. Data were analyzed by the Cochran-Mantel-Haenszel procedure.The tracheal intubating conditions were deemed acceptable in 17, 36, and 64% of infants and 20, 47, and 71% of children at 1.5, 3, or 4 min, respectively. The mean values for % of control twitch height (T1) 2 min after rapacuronium in both groups were similar. The mean (SD) time required to achieve more than or equal to 95% twitch depression in infants was 6.0 (3.7) versus 5.5 (3.8) min in children.Only 27% of patients achieved clinically acceptable tracheal intubating conditions at 1.5 or 3 min after administration of 2.8 mg/kg and 4.8 mg/kg rapacuronium during 1 minimum alveolar concentration halothane anesthesia. Tracheal intubation conditions at 4 min were acceptable in 69% of subjects. The duration of action of 4.8 mg/kg of rapacuronium in children was longer than 2.8 mg/kg of rapacuronium in infants.
Published: 2001

14. Intramuscular rocuronium in infants and children: a multicenter study to evaluate tracheal intubating conditions, onset, and duration of action

Author: R F, Kaplan, T, Uejima, G, Lobel, N, Goudsouzian, B, Ginsberg, R, Hannallah, C J, Coté, W, Denman, R, Griffith, C, Clarke, and K, Hummer
Subjects: Male, Time Factors, Laryngoscopy, Child, Preschool, Intubation, Intratracheal, Neuromuscular Junction, Humans, Infant, Female, Androstanols, Rocuronium, Injections, Intramuscular, Neuromuscular Nondepolarizing Agents
Abstract: This multicenter, assessor-blinded, randomized study was done to confirm and extend a pilot study showing that intramuscular rocuronium can provide adequate tracheal intubating conditions in infants (2.5 min) and children (3 min) during halothane anesthesia.Thirty-eight infants (age range, 3-12 months) and 38 children (age range, 1 to 5 yr) classified as American Society of Anesthesiologists physical status 1 and 2 were evaluated at four investigational sites. Anesthesia was maintained with halothane and oxygen (1% end-tidal concentration if2.5 yr; 0.80% end-tidal concentration if2.5 yr) for 5 min. One half of the patients received 0.45 mg/kg intravenous rocuronium. The others received 1 mg/kg (infants) or 1.8 mg/kg (children) of intramuscular rocuronium into the deltoid muscle. Intubating conditions and mechanomyographic responses to ulnar nerve stimulation were assessed.The conditions for tracheal intubation at 2.5 and 3 min in infants and children, respectively, were inadequate in a high percentage of patients in the intramuscular group. Nine of 16 infants and 10 of 17 children had adequate or better intubating conditions at 3.5 and 4 min, respectively, after intramuscular rocuronium. Better-than-adequate intubating conditions were achieved in 14 of 15 infants and 16 of 17 children given intravenous rocuronium. Intramuscular rocuronium providedor =98% blockade in 7.4+/-3.4 min (in infants) and 8+/-6.3 min (in children). Twenty-five percent recovery occurred in 79+/-26 min (in infants) and in 86+/-22 min (in children).Intramuscular rocuronium, in the doses and conditions tested, does not consistently provide satisfactory tracheal intubating conditions in infants and children and is not an adequate alternative to intramuscular succinylcholine when rapid intubation is necessary.
Published: 1999

15. Efficacy of ketamine hydrochloride sedation in children for interventional radiologic procedures

Author: T Uejima, M R Cotsen, James S. Donaldson, and Frank P. Morello
Subjects: Male, medicine.medical_specialty, Respiratory rate, Sedation, Conscious Sedation, Radiography, Interventional, Heart rate, medicine, Humans, Radiology, Nuclear Medicine and imaging, Ketamine, Interventional radiologic procedures, Prospective Studies, Adverse effect, Child, business.industry, Ketamine hydrochloride, Infant, Newborn, Induction time, Infant, General Medicine, Surgery, Anesthesia, Child, Preschool, Injections, Intravenous, medicine.symptom, business, medicine.drug
Abstract: The purpose of this study was to evaluate the efficacy of ketamine hydrochloride sedation in children younger than 11 years old who underwent short interventional radiologic procedures.Two hundred eleven children, 3 days to 10 years old, were given Ketalar (ketamine hydrochloride; Parke-Davis, Morris Plains, NJ), either 2 mg/kg i.v. (114 patients) or 3 mg/kg intramuscularly (i.m.) (97 patients). Atropine sulfate (Fujisawa USA, Deerfield, IL) (0.01 mg/kg i.v. or 0.02 mg/kg i.m.) was added in all patients to control secretions. Patients were monitored with continuous pulse oximetry and with automatic blood pressure cuffs. Respiratory rate and heart rate were recorded every 5 min. Adequacy of sedation was graded by the radiologist. Induction time, procedure time, recovery time, and adverse effects were recorded.Sedation was considered excellent and the procedures were completed in 191 patients (91%). The sedation was considered light but the procedures were completed in the remaining 20 patients (9%). No sedation failures were observed. Average induction time was 45 sec for the i.v. procedure and 4 min for the i.m. procedure. Average recovery time was 18 min for the i.v. procedure and 25 min for the i.m. procedure. Average procedure time for both methods was 25 min. Hemoglobin saturation remained at or greater than 95% in 200 patients (94%). Transient desaturation below 95% occurred in 11 patients (5%). The airway was manipulated to improve ventilation (head, neck, and jaw lifts) and supplemental oxygen was given via nasal cannula or mask. The episodes lasted only a few seconds and oxygen saturation promptly returned to a level greater than 95%. A 7-week-old male infant who had been born prematurely at 32 weeks' gestation experienced apnea. Ventilation was assisted for several breaths and the patient promptly recovered. We observed only minor cardiovascular changes in all patients.Ketamine hydrochloride provides excellent sedation and analgesia in young children. The short induction time, rapid recovery, and minimal respiratory depression are features that make this sedative ideal for interventional radiology.
Published: 1997

16. [Long survival after removal of a huge brain tumor which had metastasized from a lung cancer: case report]

Author: K, Kataoka, T, Uejima, K, Niiyama, R, Kuroda, N, Arita, M, Ioku, K, Yamada, M, Taneda, and T, Hayakawa
Subjects: Adenocarcinoma, Papillary, Lung Neoplasms, Brain Neoplasms, Humans, Female, Middle Aged, Prognosis
Abstract: Patients with large metastatic brain tumors are considered to have poor prognosis. We report a case of a patient with more than 33 months survival after complete resection of a huge temporal tumor which had metastasized from a lung cancer. A 57-year-old woman presented left hemiparesis and disturbance of consciousness. Magnetic resonance images revealed a huge cystic mass lesion in the right temporal lobe. After a macroscopically complete excision of the tumor, she received radiation therapy (whole brain 50 Gray). She had received lung surgery for the primary lung cancer, 2 years prior to brain metastasis. Histological examination showed papillary tubular adenocarcinoma which was similar to the previously resected lung cancer. Thirty three months after the resection of the intracranial tumor, she has no neurological deficits and no signs of recurrence of either brain tumor or lung tumor. We discuss the size of metastatic brain tumor and the postoperative prognosis of patients with metastatic brain tumor.
Published: 1994

17. Complementary DNA cloning for galactosyltransferase associated with tumor and determination of antigenic epitopes recognized by specific monoclonal antibodies

Author: T, Uejima, M, Uemura, S, Nozawa, and H, Narimatsu
Subjects: Ovarian Neoplasms, Base Sequence, Molecular Sequence Data, Antibodies, Monoclonal, Gene Expression, Sequence Homology, DNA, Neoplasm, Blotting, Northern, Galactosyltransferases, Isoenzymes, Epitopes, Antibody Specificity, Mutation, Escherichia coli, Tumor Cells, Cultured, Humans, Female, RNA, Messenger
Abstract: The galactosyltransferase associated with tumor (GAT) was the name given to the isoenzyme that tends to polymerize resulting in slower moving in a nondenaturing polyacrylamide gel electrophoresis than normal (beta 1-4)galactosyltransferase (normal GalT). A complementary DNA (cDNA) library was constructed from a human ovarian cancer cell line, RMG-I, which secreted an amount of GAT into the culture supernatant and screened with monoclonal antibodies (MAbs) against GAT and normal GalT. One of six cDNA clones, UG86-1, encoded an epitope recognized by a GAT-specific MAb, 8513. Recombinant proteins expressed by UG86-1 in Escherichia coli also had antigenic epitopes recognized by the other MAbs against normal GalT. The 229-base pair nucleotide sequence encoded by UG86-1 was identical to the stem region sequence of HGT832 which encodes a full-length cDNA of human GalT. Using recombinant proteins directed by deletion mutant cDNAs, the antigenic epitopes recognized by each MAb were determined. The epitope of MAb8628, which reacts to both the GAT and normal GalT, was localized to the COOH-terminal side of proteolytic cleavage site where the membrane-bound form enzyme is cleaved to be converted to soluble forms, while MAb8513 epitope was at the NH2-terminal side from this cleavage site between the COOH-terminal end of the membrane-binding domain and the cleavage site. These results demonstrate that GAT is produced by aberrant proteolytic cleavage at the different site, closer to the membrane-binding domain, from the normal GalT.
Published: 1992

18. Mouse monoclonal antibodies which recognize a human (beta 1-4)galactosyl-transferase associated with tumor in body fluids

Author: M, Uemura, T, Sakaguchi, T, Uejima, S, Nozawa, and H, Narimatsu
Subjects: Ovarian Neoplasms, Mice, Inbred BALB C, Antibodies, Monoclonal, Galactosyltransferases, Neoplasm Proteins, Isoenzymes, Molecular Weight, Mice, Antibody Specificity, Biomarkers, Tumor, Animals, Ascitic Fluid, Humans, Electrophoresis, Polyacrylamide Gel, Female, Immunization
Abstract: Mouse monoclonal antibodies against human (beta 1-4)galactosyl-transferase (GalT) purified from human ovarian tumor effusion fluids were prepared and characterized. GalT purified from normal human plasma showed a single diffused band in nondenaturing polyacrylamide gel electrophoresis, but GalT purified from human ovarian tumor effusion fluids showed several oligomeric bands and a monomeric band in nondenaturing polyacrylamide gel electrophoresis. These oligomeric bands were dissociated into monomer by urea treatment and polymerized by a 2-mercaptoethanol treatment. Nine monoclonal antibodies (MAb) were prepared by immunization of purified GalT from human ovarian tumor effusion fluids and classified into three groups. Type I MAbs (MAb8611, MAb8913, and MAb8919) reacted only to the GalT monomer. Type II MAbs (MAb4880, MAb8507, and MAb8628) reacted to both the GalT monomer and the GalT polymer. Type III MAbs (MAb7907, MAb8513, and MAb8677) reacted only to the GalT polymer. These MAbs except MAb7907 could recover GalT enzyme activity from effusion fluids by immunoprecipitation. A fraction passed through MAb8513 affinity chromatography still showed reactivity to MAb8919, demonstrating that an epitope of MAb8513 resides on a minor part of GalT. A sandwich immunoassay (MAb8513-MAb8628HRP) was developed, and serum samples from ovarian cancer patients and benign ovarian patients were tested. The levels of sandwich immunoassay of serum samples from cancer were elevated significantly compared to those from benign and did not necessarily correlate to total GalT enzyme activity in serum samples. These results suggested that MAb8513 (Type III) might recognize a unique GalT associated with tumor (GAT).
Published: 1992

19. [cDNA cloning of galactosyltransferase associated with tumor (GAT)]

Author: T, Uejima, M, Uemura, and H, Narimatsu
Subjects: Base Sequence, Neoplasms, Molecular Sequence Data, Humans, DNA, Cloning, Molecular, Galactosyltransferases
Published: 1992

20. Vps9 assisted guanine nucleotide exchange intermediates of Rab5

Author: M. Sunada, E. Ito, T. Goh, Soichi Wakatsuki, Kentaro Ihara, Akihiko Nakano, T. Uejima, and T. Ueda
Subjects: chemistry.chemical_classification, chemistry.chemical_compound, Structural Biology, Chemistry, Stereochemistry, Guanine, Nucleotide
Published: 2008
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21. 258 The momentum of early diastolic blood flow in the left ventricle in subjects with diastolic dysfunction

Author: S. Ohtsuki, M. Tanaka, A. Harada, T. Okada, Hitoshi Sawada, and T. Uejima
Subjects: medicine.medical_specialty, Momentum (technical analysis), E/A ratio, business.industry, Diastole, General Medicine, Blood flow, Preload, medicine.anatomical_structure, Ventricle, Internal medicine, Vascular flow, Cardiology, medicine, Early diastolic, Radiology, Nuclear Medicine and imaging, Cardiology and Cardiovascular Medicine, business
Published: 2006
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22. 729 Noninvasive evaluation of the systolic left ventricular blood flow dynamics

Author: M. Tanaka, A. Harada, T. Okada, Hitoshi Sawada, S. Ohtsuki, and T. Uejima
Subjects: medicine.medical_specialty, Ejection fraction, business.industry, Gated SPECT, General Medicine, Gold standard (test), medicine.disease, Coronary artery disease, SSS, Internal medicine, medicine, Cardiology, Radiology, Nuclear Medicine and imaging, In patient, Systole, Cardiology and Cardiovascular Medicine, Left ventricular blood flow, business
Abstract: s S121 Eur J Echocardiography Abstracts Supplement, December 2006 728 A correlative study comparing current different methods of calculating left ventricular ejection fraction A. Gholamrezanezhad 1 ; S. Mirpour 2 ; M. Saghari 1 ; B. Fallahi 1 ; D. Beiki 1 ; A. Fard-Esfahani 1 ; M. Soheilifar 3 1Azad University Of Medical Sciences, Young Researchers Club, Tehran, Iran (Islamic Republic of); 2Tehran University of Medical Sciences, Nuclear Medicine Dept., Tehran, Iran (Islamic Republic of); 3Iran University of Medical Sciences, Cardiology Dept., Tehran, Iran (Islamic Republic of) Background: Left ventricular ejection fraction (EF) is a major determinant of survival in patients with coronary artery disease (CAD). Comparative accuracy of current modalities in calculating EF is not well investigated. Method: We compared EF as calculated by rest and post-stress Cedars automated quantitative gated SPECT (AQGS), rest and post-stress semiautomatically processed gated SPECT (MQGS), echocardiography and contrast ventriculography (LVG) to those determined by rest and post-stress cavity-to-myocardium ratio (CMR) in 109 patients. Gated SPECT was performed based on 2-day protocol using Tc-MIBI. Results: Mean EF in LVG, echo, post-stress CMR, rest CMR, post-stress AQGS, rest AQGS, post-stress MQGS and rest MQGS were 41.8%±12.1, 44.8%±11.8, 38.1%±10.7, 35.7%±12.1, 44.5%±15.1, 46.9%±14.7, 40.1%±14.3 and 43.5%±14.3 respectively. Although significant differences were observed between some of these pairs, good and excellent linear correlations were present among values (all Pearson correlations >0.63). Considering LVG as gold standard, we defined 2 groups: EF 35% (class 2). Discriminant analysis showed SPECT has the ability to predict patient’s class. In 4/18 of patients with normal SPECT (on both visual and quantitative analyses, SSS =13, post-stress gated SPECT can not predict angiographic EF as accurately as patients with SSS
Published: 2006
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23. INCREASED PERIOPERATIVE MORTALITY IN YOUNG INFANTS UNDERGOING CRANIOTOMY FOR CONGENITAL TUMORS

Author: T. Uejima
Subjects: Anesthesiology and Pain Medicine, business.industry, medicine.medical_treatment, Anesthesia, medicine, Surgery, Neurology (clinical), Perioperative, business, Craniotomy, Young infants
Published: 1991
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24. EFFECT OF SODIUM BICARBONATE ON PAIN WITH SKIN INFILTRATION AND ON LOCAL ANESTHETIC STABILITY

Author: P. Dixit, H. T. Benzon, and T. Uejima
Subjects: chemistry.chemical_compound, medicine.medical_specialty, Anesthesiology and Pain Medicine, Sodium bicarbonate, chemistry, Local anesthetic, medicine.drug_class, business.industry, Anesthesia, medicine, Skin infiltration, business, Surgery
Published: 1990
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25. Studies on the relation between the physical characters of lipuid chemicals and effectiveness in the field, (I)

Author: T. Uejima and H. Yamashina
Subjects: Theoretical physics, Field (physics), Relation (database), Mathematics
Abstract: 物理性の異なる2種展着剤をパラチオン水和剤に加用した場合の水稲に対する附着量及び喰入螟虫に対する効果について実験を行つたが,拡展係数の劣るNo,6がNo.1より良い傾向を示し.附着量を支配する因子として拡展係数の他に中に含まれる成分組成も亦見逃せない問題があるのではないかと考えられた.
Published: 1955
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26. Cardiopulmonary bypass in patients with malignant renal neoplasms

Author: M.A. Kimovec, C.J. Wilkinson, and T. Uejima
Subjects: Male, medicine.medical_specialty, medicine.medical_treatment, Embolectomy, Vena Cava, Inferior, law.invention, Renal neoplasm, Malignant Renal Neoplasm, Pulmonary embolectomy, law, medicine, Cardiopulmonary bypass, Humans, In patient, Intraoperative Complications, Carcinoma, Renal Cell, Kidney, Cardiopulmonary Bypass, business.industry, Middle Aged, medicine.disease, Neoplastic Cells, Circulating, Kidney Neoplasms, Surgery, Pulmonary embolism, Anesthesiology and Pain Medicine, medicine.anatomical_structure, Emergencies, business, Pulmonary Embolism
Abstract: A case report of a patient with malignant renal neoplasm who underwent emergency pulmonary embolectomy during operation is presented. Knowledge of degree of venous extension, appropriate operative positioning of the patient and consideration of elective cardiopulmonary bypass are suggested ways to reduce morbidity and mortality from massive pulmonary emboli in these patients.
Published: 1986

27. Isolated postoperative myoglobinuria in a pediatric outpatient. A case report of malignant hyperthermia

Author: P K, Birmingham, G W, Stevenson, T, Uejima, and S C, Hall
Subjects: Male, Ambulatory Surgical Procedures, Gastroscopy, Myoglobinuria, Humans, Succinylcholine, Child, Malignant Hyperthermia, Rhabdomyolysis
Published: 1989

28. [Anesthesia and hemodynamics in the brain, with special reference to changes of ocular fundus]

Author: S, Seino, K, Kamijo, T, Uejima, S, Maeda, and M, Takimoto
Subjects: Dogs, Fundus Oculi, Cerebrovascular Circulation, Hemodynamics, Animals, Anesthesia
Published: 1969

29. Some considerations on the lethal minimum deposited dose of Parathion for rice stem borer bored into rice plant

Author: H. Yamashina, B. Hashizume, and T. Uejima
Subjects: chemistry.chemical_compound, Parathion, chemistry, Agronomy, Biology, Rice plant
Published: 1955
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30. Association between ventricular arrhythmia (premature ventricular contractions burden and nonsustained ventricular tachycardia) and cardiovascular events in patients without structural heart disease.

Author: Ogiso S, Arita T, Suzuki S, Hirota N, Yagi N, Otsuka T, Kishi M, Kano H, Matsuno S, Kato Y, Uejima T, Oikawa Y, Ako J, Yajima J, and Yamashita T
Abstract: Background: Premature ventricular contractions (PVCs) and nonsustained ventricular tachycardia (NSVT) are common arrhythmias in cardiovascular clinical settings. However, the clinical significance of PVCs and NSVT in the absence of structural heart disease has not yet been fully elucidated. This study aimed to evaluate the association between PVCs, NSVT, and clinical outcomes., Methods: A study population of 26,117 patients was drawn from the Shinken Database established in June 2004. We enrolled 6332 patients without structural heart disease who underwent 24-h Holter monitoring and were registered up to March 2019. We focused on ventricular arrhythmias and cardiovascular events in patients without structural heart diseases. The study population was divided by the number of baseline PVCs (PVCs: <1000 ( n = 5507), 1000-9999 ( n = 531), and 10 000 ≤( n = 294)). The study population was also divided according to the presence or absence of NSVT ( n = 454 and n = 5878, respectively)., Result: During the follow-up period up to 3 years, there were 16 deaths, 24 heart failure-related hospitalizations, 14 acute coronary syndromes, and 37 embolism events. The frequency of PVCs was not associated with mortality or heart failure. On the other hand, the presence of NSVT was significantly associated with heart failure hospitalization in a multivariate model (hazard ratio: 3.02; 95% CI: 1.03-8.83; p = .044)., Conclusion: In patients without structural heart disease, NSVT was associated with a higher risk of heart failure hospitalization. Patients with NSVT but no structural heart diseases require careful follow-up and management of heart failure risk factors., Competing Interests: Dr. Suzuki has received lecture fees from Daiichi Sankyo and Bristol‐Myers Squibb. Dr. Yamashita has received research funding and/or lecture fees from Daiichi Sankyo, Bayer Yakuhin, Bristol‐Myers Squibb, Pfizer, Nippon Boehringer Ingelheim, Ono Pharmaceutical, and Toa Eiyo., (© 2024 The Author(s). Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of Japanese Heart Rhythm Society.)
Published: 2024
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31. EVA1-Antibody Drug Conjugate is a new therapeutic strategy for eliminating glioblastoma-initiating cells.

Author: Hou J, Uejima T, Tanaka M, Son YL, Hanada K, Kukimoto-Niino M, Yamaguchi S, Hashimoto S, Yokoyama S, Takemori T, Saito T, Shirouzu M, and Kondo T
Abstract: Background: The discovery of glioblastoma (GBM)-initiating cells (GICs) has impacted GBM research. These cells are not only tumorigenic, but also exhibit resistance to radiotherapy and chemotherapy. Therefore, it is crucial to characterize GICs thoroughly and identify new therapeutic targets. In a previous study, we successfully identified Epithelial V-like antigen 1 (EVA1) as a novel functional factor specific to GICs., Methods: Hybridoma cells were generated by immunizing BALB/c mice with EVA1-Fc fusion protein. The reactivity of the supernatant from these hybridoma cells was examined using EVA1-overexpressing cells and GICs. Candidate antibodies were further selected using Biacore surface plasmon resonance analysis and two cytotoxicity assays, antibody-dependent cell cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). Among the antibodies, the cytotoxicity of the B2E5-antibody drug conjugate (B2E5-ADC) was evaluated by both adding it to cultured GICs and injecting it into GIC tumor-bearing brains., Results: B2E5 demonstrated a high affinity for human EVA1 and effectively killed both EVA1-expressing cell lines and GICs in culture through ADCC and CDC. B2E5-ADC also exhibited strong cytotoxicity to GICs in culture and prevented their tumorigenesis in the brain when administered intracranially to the tumor-bearing brain., Conclusion: Our data indicate that B2E5-ADC is a new and promising therapeutic strategy for GBM., (© The Author(s) 2024. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
Published: 2024
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32. Evaluating convolutional neural network-enhanced electrocardiography for hypertrophic cardiomyopathy detection in a specialized cardiovascular setting.

Author: Hirota N, Suzuki S, Motogi J, Umemoto T, Nakai H, Matsuzawa W, Takayanagi T, Hyodo A, Satoh K, Arita T, Yagi N, Kishi M, Semba H, Kano H, Matsuno S, Kato Y, Otsuka T, Uejima T, Oikawa Y, Hori T, Matsuhama M, Iida M, Yajima J, and Yamashita T
Subjects: Humans, Retrospective Studies, Male, Female, Middle Aged, Predictive Value of Tests, Adult, Aged, Cardiomyopathy, Hypertrophic diagnosis, Cardiomyopathy, Hypertrophic physiopathology, Cardiomyopathy, Hypertrophic complications, Electrocardiography methods, Neural Networks, Computer
Abstract: The efficacy of convolutional neural network (CNN)-enhanced electrocardiography (ECG) in detecting hypertrophic cardiomyopathy (HCM) and dilated HCM (dHCM) remains uncertain in real-world applications. This retrospective study analyzed data from 19,170 patients (including 140 HCM or dHCM) in the Shinken Database (2010-2017). We evaluated the sensitivity, positive predictive rate (PPR), and F1 score of CNN-enhanced ECG in a ''basic diagnosis'' model (total disease label) and a ''comprehensive diagnosis'' model (including disease subtypes). Using all-lead ECG in the "basic diagnosis" model, we observed a sensitivity of 76%, PPR of 2.9%, and F1 score of 0.056. These metrics improved in cases with a diagnostic probability of ≥ 0.9 and left ventricular hypertrophy (LVH) on ECG: 100% sensitivity, 8.6% PPR, and 0.158 F1 score. The ''comprehensive diagnosis'' model further enhanced these figures to 100%, 13.0%, and 0.230, respectively. Performance was broadly consistent across CNN models using different lead configurations, particularly when including leads viewing the lateral walls. While the precision of CNN models in detecting HCM or dHCM in real-world settings is initially low, it improves by targeting specific patient groups and integrating disease subtype models. The use of ECGs with fewer leads, especially those involving the lateral walls, appears comparably effective., (© 2024. Springer Nature Japan KK, part of Springer Nature.)
Published: 2024
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33. Descriptions of Etiology, Clinical Course, and Prognosis of Patients Presenting with Pericardial Effusion.

Author: Hori K, Kato Y, Suzuki S, Hirota N, Arita T, Yagi N, Kishi M, Kano H, Matsuno S, Otsuka T, Hori T, Matsuhama M, Iida M, Yajima J, Yamashita T, Uejima T, and Oikawa Y
Subjects: Humans, Male, Female, Retrospective Studies, Aged, Middle Aged, Prognosis, Echocardiography, Hospitalization statistics & numerical data, Cause of Death, Heart Failure etiology, Heart Failure epidemiology, Adult, Aged, 80 and over, Neoplasms complications, Japan epidemiology, Pericardial Effusion etiology, Pericardial Effusion epidemiology
Abstract: Pericardial effusion (PE) presentation varies from an incidental finding to a life-threatening situation; thus, its etiology and clinical course remain unknown. The aim of the present study was to retrospectively investigate these factors.We analyzed 171 patients (0.4%) who presented with PE among 34,873 patients who underwent echocardiography between 2011 and 2021 at our hospital. Clinical and prognostic information was retrieved from electronic medical records. The primary endpoints were all-cause death, hospitalization due to heart failure (HF), and other cardiovascular events such as cardiovascular death, acute coronary syndrome, elective percutaneous coronary intervention, and stroke.The etiologies of PE were as follows: idiopathic (32%), HF-related (18%), iatrogenic (11%), cardiac surgery-related (10%), radiation therapy-related (9%), malignancy (8%), pericarditis/myocarditis (8%), myocardial infarction-related (2%), and acute aortic dissection (2%). Patients with idiopathic/HF etiology were more likely to be older than the others.During a mean follow-up period of 2.5 years, all-cause death occurred in 21 patients (12.3%), cardiovascular events in 10 patients (5.8%), and hospitalization for HF in 24 patients (14.0%). All-cause death was frequently observed in patients with malignancy (44% per person-year). Cardiovascular events were mostly observed in patients with radiation therapy-related and malignancy (8.6% and 7.3% per person-year, respectively).The annual incidence of hospitalization for HF was the highest in patients with HF-related (25.1% per person-year), followed by radiation therapy-related (10.4% per person-year).This retrospective study is the first, to the best of our knowledge, to reveal the contemporary prevalence of PE, its cause, and outcome in patients who visited a cardiovascular hospital in an urban area of Japan.
Published: 2024
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34. Identifying patients with acute aortic dissection using an electrocardiogram with convolutional neural network.

Author: Arita T, Suzuki S, Motogi J, Umemoto T, Hirota N, Nakai H, Matsuzawa W, Takayanagi T, Hyodo A, Satoh K, Yagi N, Otsuka T, Kishi M, Kano H, Matsuno S, Kato Y, Uejima T, Oikawa Y, Hori T, Matsuhama M, Iida M, Yajima J, and Yamashita T
Abstract: Background: The potential of utilizing artificial intelligence with electrocardiography (ECG) for initial screening of aortic dissection (AD) is promising. However, achieving a high positive predictive rate (PPR) remains challenging., Methods and Results: This retrospective analysis of a single-center, prospective cohort study (Shinken Database 2010-2017, N = 19,170) used digital 12-lead ECGs from initial patient visits. We assessed a convolutional neural network (CNN) model's performance for AD detection with eight-lead (I, II, and V1-6), single-lead, and double-lead (I, II) ECGs via five-fold cross-validation. The mean age was 63.5 ± 12.5 years for the AD group (n = 147) and 58.1 ± 15.7 years for the non-AD group (n = 19,023). The CNN model achieved an area under the curve (AUC) of 0.936 (standard deviation [SD]: 0.023) for AD detection with eight-lead ECGs. In the entire cohort, the PPR was 7 %, with 126 out of 147 AD cases correctly diagnosed (sensitivity 86 %). When applied to patients with D-dimer levels ≥1 μg/dL and a history of hypertension, the PPR increased to 35 %, with 113 AD cases correctly identified (sensitivity 86 %). The single V1 lead displayed the highest diagnostic performance (AUC: 0.933, SD: 0.03), with PPR improvement from 8 % to 38 % within the same population., Conclusions: Our CNN model using ECG data for AD detection achieved an over 30% PPR when applied to patients with elevated D-dimer levels and hypertension history while maintaining sensitivity. A similar level of performance was observed with a single-lead V1 ECG in the CNN model., Competing Interests: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Dr. Suzuki has received lecture fees from Daiichi Sankyo and Bristol-Myers Squibb. Dr. Yamashita has received research funding and/or lecture fees from Daiichi Sankyo, Bayer Yakuhin, Bristol-Myers Squibb, Pfizer, Nippon Boehringer Ingelheim, Ono Pharmaceutical, and Toa Eiyo. J Motogi, T Umemoto, W Matsuzawa, T Takayanagi, A Hyodo, and K Satoh are employee at Nihon Kohden Corporation., (© 2024 The Authors.)
Published: 2024
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35. Lead-Specific Performance for Atrial Fibrillation Detection in Convolutional Neural Network Models Using Sinus Rhythm Electrocardiography.

Author: Suzuki S, Motogi J, Umemoto T, Hirota N, Nakai H, Matsuzawa W, Takayanagi T, Hyodo A, Satoh K, Arita T, Yagi N, Kishi M, Semba H, Kano H, Matsuno S, Kato Y, Otsuka T, Hori T, Matsuhama M, Iida M, Uejima T, Oikawa Y, Yajima J, and Yamashita T
Abstract: Background: We developed a convolutional neural network (CNN) model to detect atrial fibrillation (AF) using the sinus rhythm ECG (SR-ECG). However, the diagnostic performance of the CNN model based on different ECG leads remains unclear. Methods and Results: In this retrospective analysis of a single-center, prospective cohort study, we identified 616 AF cases and 3,412 SR cases for the modeling dataset among new patients (n=19,170). The modeling dataset included SR-ECGs obtained within 31 days from AF-ECGs in AF cases and SR cases with follow-up ≥1,095 days. We evaluated the CNN model's performance for AF detection using 8-lead (I, II, and V1-6), single-lead, and double-lead ECGs through 5-fold cross-validation. The CNN model achieved an area under the curve (AUC) of 0.872 (95% confidence interval (CI): 0.856-0.888) and an odds ratio of 15.24 (95% CI: 12.42-18.72) for AF detection using the eight-lead ECG. Among the single-lead and double-lead ECGs, the double-lead ECG using leads I and V1 yielded an AUC of 0.871 (95% CI: 0.856-0.886) with an odds ratio of 14.34 (95% CI: 11.64-17.67). Conclusions: We assessed the performance of a CNN model for detecting AF using eight-lead, single-lead, and double-lead SR-ECGs. The model's performance with a double-lead (I, V1) ECG was comparable to that of the 8-lead ECG, suggesting its potential as an alternative for AF screening using SR-ECG., Competing Interests: S.S. received lecture fees from Daiichi Sankyo and Bristol-Myers Squibb. T.Y. received research funds and/or lecture fees from Daiichi Sankyo, Bayer Yakuhin, Bristol-Myers Squibb, Pfizer, Nippon Boehringer Ingelheim, Eisai, Mitsubishi Tanabe Pharm, Ono Pharmaceutical, and Toa Eiyo. The remaining authors have nothing to disclose., (Copyright © 2024, THE JAPANESE CIRCULATION SOCIETY.)
Published: 2024
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36. The influence of stereopsis on visual saliency in a proto-object based model of selective attention.

Author: Uejima T, Mancinelli E, Niebur E, and Etienne-Cummings R
Subjects: Humans, Eye Movements physiology, Vision Disparity physiology, Attention physiology, Depth Perception physiology, Vision, Binocular physiology
Abstract: Some animals including humans use stereoscopic vision which reconstructs spatial information about the environment from the disparity between images captured by eyes in two separate adjacent locations. Like other sensory information, such stereoscopic information is expected to influence attentional selection. We develop a biologically plausible model of binocular vision to study its effect on bottom-up visual attention, i.e., visual saliency. In our model, the scene is organized in terms of proto-objects on which attention acts, rather than on unbound sets of elementary features. We show that taking into account the stereoscopic information improves the performance of the model in the prediction of human eye movements with statistically significant differences., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Published: 2023
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37. Diagnostic posture control system for seated-style echocardiography robot.

Author: Shida Y, Sugawara M, Tsumura R, Chiba H, Uejima T, and Iwata H
Subjects: Humans, Posture, Echocardiography, Postural Balance, Sitting Position, Robotics
Abstract: Purpose: Conventional robotic ultrasound systems were utilized with patients in supine positions. Meanwhile, the limitation of the systems is that it is difficult to evacuate the patients in case of emergency (e.g., patient discomfort and system failure) because the patients are restricted between the robot system and bed. Therefore, we validated a feasibility study of seated-style echocardiography using a robot., Method: Preliminary experiments were conducted to verify the following two points: (1) diagnostic image quality due to the sitting posture angle and (2) physical load due to the sitting posture angle. For reducing the physical burden, two unique mechanisms were incorporated into the system: (1) a leg pendulum base mechanism to reduce the load on the legs when the lateral bending angle increases, and (2) a roll angle division by a lumbar lateral bending and thoracic rotation mechanisms., Results: Preliminary results demonstrated that adjusting the diagnostic posture angle allowed to obtain the views, including cardiac disease features, as in the conventional examination. The results also demonstrated that the body load reduction mechanism incorporated in the results could reduce the physical load in the seated echocardiography. Furthermore, this system was shown to provide greater safety and shorter evacuation times than conventional systems., Conclusion: These results indicate that diagnostic echocardiographic images can be obtained by seated-style echocardiography. It was also suggested that the proposed system can reduce the physical load and guarantee a sense of safety and emergency evacuation. These results demonstrated the possibility of the usage of the seated-style echocardiography robot., (© 2023. The Author(s).)
Published: 2023
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38. Identification of patients with dilated phase of hypertrophic cardiomyopathy using a convolutional neural network applied to multiple, dual, and single lead electrocardiograms.

Author: Hirota N, Suzuki S, Motogi J, Umemoto T, Nakai H, Matsuzawa W, Takayanagi T, Hyodo A, Satoh K, Arita T, Yagi N, Kishi M, Semba H, Kano H, Matsuno S, Kato Y, Otsuka T, Uejima T, Oikawa Y, Hori T, Matsuhama M, Iida M, Yajima J, and Yamashita T
Abstract: Background: This study sought to develop an artificial intelligence-derived model to detect the dilated phase of hypertrophic cardiomyopathy (dHCM) on digital electrocardiography (ECG) and to evaluate the performance of the model applied to multiple-lead or single-lead ECG., Methods: This is a retrospective analysis using a single-center prospective cohort study (Shinken Database 2010-2017, n = 19,170). After excluding those without a normal P wave on index ECG (n = 1,831) and adding dHCM patients registered before 2009 (n = 39), 17,378 digital ECGs were used. Totally 54 dHCM patients were identified of which 11 diagnosed at baseline, 4 developed during the time course, and 39 registered before 2009. The performance of the convolutional neural network (CNN) model for detecting dHCM was evaluated using eight-lead (I, II, and V1-6), single-lead, and double-lead (I, II) ECGs with the five-fold cross validation method., Results: The area under the curve (AUC) of the CNN model to detect dHCM (n = 54) with eight-lead ECG was 0.929 (standard deviation [SD]: 0.025) and the odds ratio was 38.64 (SD 9.10). Among the single-lead and double-lead ECGs, the AUC was highest with the single lead of V5 (0.953 [SD: 0.038]), with an odds ratio of 58.89 (SD:68.56)., Conclusion: Compared with the performance of eight-lead ECG, the most similar performance was achieved with the model with a single V5 lead, suggesting that this single-lead ECG can be an alternative to eight-lead ECG for the screening of dHCM., Competing Interests: Dr. Suzuki received lecture fees from Daiichi Sankyo and Bristol-Myers Squibb. Dr. Yamashita received research funds and/or lecture fees from Daiichi Sankyo, Bayer Yakuhin, Bristol-Myers Squibb, Pfizer, Nippon Boehringer Ingelheim, Eisai, Mitsubishi Tanabe Pharm, Ono Pharmaceutical, and Toa Eiyo. J Motogi, T Umemoto, W Matsuzawa, T Takayanagi, A Hyodo, and K Satoh are employee at Nihon Kohden Corporation.The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Shinya Suzuki reports a relationship with Public Interest Incorporated Foundation The Cardiovascular Institute that includes: speaking and lecture fees. Takeshi Yamashita reports a relationship with Public Interest Incorporated Foundation The Cardiovascular Institute that includes: funding grants and speaking and lecture fees., (© 2023 The Author(s).)
Published: 2023
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39. The past, present and future of ACS NSQIP-Pediatric: Evolution from a quality registry to a comparative quality performance platform.

Author: Saito JM, Barnhart DC, Grant C, Brighton BK, Raval MV, Campbell BT, Kenney B, Jatana KR, Ellison JS, Cina RA, Allori AC, Uejima T, Roke D, Lam S, Johnson EK, Goretsky MJ, Byrd C, Iwaniuk M, Nayak R, Thompson VM, Cohen ME, Hall BL, Ko CY, and Rangel SJ
Subjects: Child, Humans, United States, Child, Preschool, Registries, Program Development, Postoperative Complications prevention & control, Quality Improvement, Tracheostomy
Abstract: Quality and process improvement (QI/PI) in children's surgical care require reliable data across the care continuum. Since 2012, the American College of Surgeons' (ACS) National Surgical Quality Improvement Program-Pediatric (NSQIP-Pediatric) has supported QI/PI by providing participating hospitals with risk-adjusted, comparative data regarding postoperative outcomes for multiple surgical specialties. To advance this goal over the past decade, iterative changes have been introduced to case inclusion and data collection, analysis and reporting. New datasets for specific procedures, such as appendectomy, spinal fusion for scoliosis, vesicoureteral reflux procedures, and tracheostomy in children less than 2 years old, have incorporated additional risk factors and outcomes to enhance the clinical relevance of data, and resource utilization to consider healthcare value. Recently, process measures for urgent surgical diagnoses and surgical antibiotic prophylaxis variables have been developed to promote timely and appropriate care. While a mature program, NSQIP-Pediatric remains dynamic and responsive to meet the needs of the surgical community. Future directions include introduction of variables and analyses to address patient-centered care and healthcare equity., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023. Published by Elsevier Inc.)
Published: 2023
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40. Association between serum alkaline phosphatase and cardiovascular events in patients with atrial fibrillation.

Author: Yagi N, Suzuki S, Arita T, Otsuka T, Kishi M, Semba H, Kano H, Matsuno S, Kato Y, Uejima T, Oikawa Y, Matsuhama M, Iida M, Yajima J, and Yamashita T
Subjects: Humans, Retrospective Studies, Risk Factors, Alkaline Phosphatase blood, Atrial Fibrillation diagnosis, Atrial Fibrillation epidemiology, Atrial Fibrillation complications, Heart Failure diagnosis, Heart Failure epidemiology, Heart Failure etiology, Renal Insufficiency, Chronic complications
Abstract: High alkaline phosphatase (ALP) levels are reported to be associated with an increased risk of cardiovascular events in patients with chronic kidney disease (CKD). Given the pathological link with CKD, a similar relationship may exist in patients with atrial fibrillation (AF). We retrospectively evaluated 1,719 patients with AF and normal hepatic function who were registered in the Shinken Database between November 2011 and March 2017. Study patients were divided into three groups according to ALP value tertiles with cut-offs of 175 and 227 IU/L (normal range: 95-350 IU/L). Each group's incidence rate was recorded, and the risks of cardiovascular events and each component for patients in the middle and high ALP tertiles were compared with those in the low tertile and evaluated using Cox regression models. The additional predictive value of the high ALP tertile over the existing risk scores for the components of cardiovascular events was evaluated via receiver operating characteristic (ROC) curve analysis. During the median follow-up of 731 days (IQR: 444-1095 days), 137 cardiovascular events occurred, with incidence rates of 2.94%, 3.44%, and 6.19%/person-year for the low, middle, and high ALP tertiles, respectively. Of these cardiovascular events, heart failure had the highest incidence rates (1.34%, 1.89%, and 4.29%/person-year for the low, middle, and high ALP tertiles, respectively) and the incidence rates of the other components of cardiovascular event were similar in each ALP groups. Multivariate Cox regression analysis yielded hazard ratios of 1.22 (95% confidence interval [CI] 0.70-1.96) and 1.62 (95% CI 1.06-2.48) for cardiovascular events and 1.66 (95% CI 0.87-3.15) and 2.50 (95% CI 1.39-4.48) for heart failure admission in the middle and high ALP tertiles, respectively. By ROC curve analysis for heart failure admission showed that the high ALP tertile lacked significant additive predictive value over the existing risk scores. High serum ALP levels, even those in the normal range, were significantly associated with an increased risk of cardiovascular events, especially heart failure admission in patients with AF., (© 2022. Springer Japan KK, part of Springer Nature.)
Published: 2023
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41. Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1.

Author: Hirano R, Ehara H, Kujirai T, Uejima T, Takizawa Y, Sekine SI, and Kurumizaka H
Subjects: RNA Polymerase II metabolism, Cryoelectron Microscopy, DNA metabolism, Histones metabolism, Nucleosomes
Abstract: In chromatin, linker histone H1 binds to nucleosomes, forming chromatosomes, and changes the transcription status. However, the mechanism by which RNA polymerase II (RNAPII) transcribes the DNA in the chromatosome has remained enigmatic. Here we report the cryo-electron microscopy (cryo-EM) structures of transcribing RNAPII-chromatosome complexes (forms I and II), in which RNAPII is paused at the entry linker DNA region of the chromatosome due to H1 binding. In the form I complex, the H1 bound to the nucleosome restricts the linker DNA orientation, and the exit linker DNA is captured by the RNAPII DNA binding cleft. In the form II complex, the RNAPII progresses a few bases ahead by releasing the exit linker DNA from the RNAPII cleft, and directly clashes with the H1 bound to the nucleosome. The transcription elongation factor Spt4/5 masks the RNAPII DNA binding region, and drastically reduces the H1-mediated RNAPII pausing., (© 2022. The Author(s).)
Published: 2022
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42. Relationship between the prescription of sleep inducers and prognosis in patients with cardiovascular diseases.

Author: Fujii E, Kato Y, Suzuki S, Uejima T, Arita T, Yagi N, Kishi M, Kano H, Matsuno S, Otsuka T, Oikawa Y, Matsuhama M, Iida M, Inoue T, Yajima J, and Yamashita T
Subjects: Humans, Prognosis, Prescriptions, Sleep, Risk Factors, Cardiovascular Diseases diagnosis, Cardiovascular Diseases epidemiology, Sleep Aids, Pharmaceutical
Abstract: Competing Interests: Conflict of interest: None declared.
Published: 2022
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43. Glasgow prognostic score can be a prognostic indicator after percutaneous coronary intervention: a two-center study in Japan.

Author: Noike R, Amano H, Suzuki S, Kano H, Oikawa Y, Yajima J, Hirano S, Kojima Y, Oka Y, Aikawa H, Matsumoto S, Yabe T, Okubo R, Nakanishi R, Arita T, Yagi N, Kishi M, Semba H, Matsuno S, Kato Y, Otsuka T, Uejima T, Matsuhama M, Iida M, Yamashita T, and Ikeda T
Subjects: Humans, Japan epidemiology, Prognosis, Retrospective Studies, Heart Failure etiology, Percutaneous Coronary Intervention adverse effects, Renal Insufficiency, Chronic etiology
Abstract: Glasgow prognostic score (GPS) has been used to evaluate inflammatory response and nutritional status. This study aimed to investigate the impact of nutritional status on cardiac prognosis by using GPS in patients after undergoing percutaneous coronary intervention (PCI). We included 862 patients who underwent PCI for stable angina pectoris between 2015 and 2018. We used the original cutoff values, which were an albumin (Alb) level of 3.5 g/dl and a C-reactive protein (CRP) level of 0.3 mg/dl. We categorized them into the three groups: originally defined GPS (od-GPS) 0 (high Alb and low CRP), 1 (low Alb or high CRP), and 2 (low Alb and high CRP). Major adverse clinical events (MACEs) included all-cause death, nonfatal myocardial infarction, revascularization, and hospitalization for heart failure. The median follow-up period was 398.5 days. During the follow-up, MACEs occurred in 136 patients. Od-GPS 2 had higher prevalence rates in terms of chronic kidney disease (CKD; 31.7% [229/722] vs. 44.9% [53/118] vs. 63.6% [14/22], p < 0.001), hemodialysis (6.4% [46/722] vs. 14.4% [17/118] vs. 31.8% [7/22], p < 0.001), and heart failure cases (HF; 9.1% [66/722] vs. 14.4% [17/118] vs. 27.3% [6/22], p = 0.007), with higher creatinine (1.17 ± 1.37 mg/dl vs. 1.89 ± 2.60 mg/dl vs. 3.49 ± 4.01 mg/dl, p < 0.001) and brain natriuretic peptide levels (104.1 ± 304.6 pg/ml vs. 242.4 ± 565.9 pg/ml vs. 668.1 ± 872.2 pg/ml, p < 0.001) and lower low-density lipoprotein cholesterol (101.5 ± 32.9 mg/dl vs. 98.2 ± 28.8 mg/dl vs. 77.1 ± 24.3 mg/dl, p = 0.002) than od-GPS 0 and 1.Od-GPS 2 (HR 2.42; 95% CI 1.16-5.02; p = 0.018), od-GPS 1 (HR 2.09; 95% CI 1.40-3.13; p < 0.001), diabetes (HR 1.41; 95% CI 1.00-1.99; p = 0.048), CKD (HR 2.10; 95% CI 1.49-2.96; p < 0.001), and HF (HR 1.64; 95% CI 1.05-2.56; p = 0.029) were independent predictors of MACEs. A scoring system using CRP and Alb levels with a milder definition than GPS suitably predicted the risk of MACEs in the patients who underwent PCI., (© 2021. Springer Japan KK, part of Springer Nature.)
Published: 2022
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44. A Novel Non-Invasive Method for Estimating Elevated Pulmonary Vascular Resistance Based on Echocardiographic Assessment of Pulmonary Artery Wave Reflection.

Author: Hayama H, Moroi M, Adachi-Akahane S, Uejima T, Hara H, and Hiroi Y
Subjects: Cardiac Catheterization methods, Echocardiography methods, Humans, Lead, Vascular Resistance, Hypertension, Pulmonary diagnostic imaging, Pulmonary Artery diagnostic imaging
Abstract: Background: Several non-invasive methods for pulmonary vascular resistance (PVR) measurement are proposed, but none are sufficiently accurate for use in clinical practice. This study proposes a new echocardiographic method of pulmonary artery wave reflection and investigates its efficacy in managing patients with pulmonary hypertension., Methods and results: In total, 83 patients with left heart disease, pulmonary arterial hypertension, and chronic thromboembolic pulmonary hypertension (CTEPH), who underwent Doppler echocardiography and right heart catheterization, were included in the study. Pulmonary artery wave reflection was characterized by separating the pulmonary artery pressure waveform into forward and backward (Pb) waves, based on wave intensity. Pulmonary artery pressure waveforms were estimated from continuous Doppler tracings of tricuspid regurgitation velocity, and flow velocity was measured using pulsed Doppler of the right ventricular outflow tract. Pb-peak was compared with catheter hemodynamic indices, and with PVR by Abbas 2003, 2013 and Haddad in relation to increased catheter PVR. Catheter PVR and Pb were strongly correlated (r=0.77, P<0.001). The areas under the receiver operator characteristic curve for Pb-peak, PVR by Abbas 2003, 2013 and Haddad were 0.91, 0.72, 0.80, and 0.80, respectively, and were used to detect an increase in PVR (>3 Woods units)., Conclusions: This study describes a novel, simple, and non-invasive echocardiography method to assess pulmonary wave reflected pressure to identify patients with pulmonary hypertension due to increased PVR.
Published: 2022
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45. Medical students' perceptions of emergency medical care before and during the coronavirus disease 2019 pandemic.

Author: Uejima T, Ota I, Hamaguchi M, Shigeoka H, Kurita T, and Hiraide A
Abstract: Aim: Understanding how medical students perceive emergency medical care is important in promoting education and recruitment in the field of emergency medicine. This study aimed to clarify the perceptions of undergraduate medical students on emergency medical care with a focus on comparing their perceptions before and during the coronavirus disease 2019 (COVID-19) pandemic., Methods: Fourth-year undergraduate medical students were invited to complete a self-administered questionnaire in 2017 and 2020. Free comments on emergency medical care were analyzed via text mining. The relationships among categorical words were evaluated via correlation matrix and correspondence analysis., Results: The number of written words per student were not significantly different between 2017 (4.9 ± 3.4) and 2020 (5.3 ± 4.1). In 2017, the most frequently used word was "busy," and the words "patients," "life," and "care" were not related to each other significantly. In 2020, the frequency of the word "busy" decreased and the word "patients" was related to "life" ( P < 0.01) and "care" ( P < 0.01). In the correspondence analysis, seven words including "life" and "care" were associated with "patients," which demonstrates that these words tended to occur together., Conclusions: Although the responses of the medical students regarding emergency medical care before and during the COVID-19 pandemic included similar words, their expressions tended to be related to patient care or patient life during the pandemic. This change in perception might cultivate a sense of mission and responsibility and an interest in emergency medical care among medical students., (© 2022 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine.)
Published: 2022
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46. Early diastolic mitral regurgitation in left ventricular aneurysm.

Author: Uema A, Tamura Y, Uejima T, Hoshiai M, Ueno A, Nagao M, Tomoe T, Ono S, Maeno E, Mizuguchi S, Kawabe A, Sugiyama T, and Yasu T
Subjects: Diastole, Humans, Male, Systole, Ventricular Function, Left, Ventricular Pressure, Mitral Valve Insufficiency diagnosis, Mitral Valve Insufficiency etiology, Ventricular Dysfunction, Left
Abstract: Diastolic mitral regurgitation is a type of functional mitral regurgitation that develops via a reversal of the left atrioventricular pressure gradient during diastole. This study aimed to explore the mechanism underlying early diastolic mitral regurgitation (EDMR) in patients with left ventricular (LV) aneurysms after anterior myocardial infarction (AMI) by assessing the intraventricular pressure difference using vector flow mapping. We enrolled 23 consecutive patients with LV aneurysms (with and without EDMR) and 15 healthy men as controls. In the control group, LV suction began from the apex during early diastole. In contrast, the blood that pooled in the apical aneurysm during systole generated a relatively higher pressure at the apex than at the basal LV during early diastole; consequently, the pressure reversal phenomenon occurred in the LV. Compared to the EDMR- group, the EDMR + group (n = 7) exhibited a significantly higher diastolic time ratio ([time from the second heart sound to the pressure inversion point]/[total diastolic time]) (P < 0.001). The diastolic time ratio was significantly correlated with log BNP, but not with E/A, E/E', or the left atrial expansion index. In conclusion, EDMR in LV aneurysm may be due to a prolonged diastolic time ratio leading to prolonged pressure inversion in the LV during early diastole., (© 2021. Springer Japan KK, part of Springer Nature.)
Published: 2022
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47. Blood culture-negative prosthetic valve endocarditis and daptomycin-associated eosinophilic pneumonia: A case report.

Author: Fujii E, Arita T, Uejima T, Matsuhama M, Iida M, Inoue T, Yajima J, and Yamashita T
Abstract: Acute eosinophilic pneumonia is a rare but severe side effect of daptomycin, which has been recommended as empirical antimicrobial drug therapy for blood culture-negative prosthetic valve endocarditis. Here, we present a case of an 82-year-old man who developed fever, cough, and shortness of breath after 23-day treatment with daptomycin for prosthetic valve endocarditis. Bilateral ground-glass opacities were observed on computed tomography with peripheral eosinophilia of 640/μL (7%). Cessation of daptomycin and commencement of corticosteroid therapy improved his symptoms. This case highlights the importance of prompt diagnosis of acute eosinophilic pneumonia in endocarditis patients treated with daptomycin. < Learning objective: Acute eosinophilic pneumonia is a rare but severe side effect of daptomycin, which has been recommended as empirical antimicrobial drug therapy for blood culture-negative endocarditis. As an alternative to vancomycin for treatment of methicillin-resistant Staphylococcus aureus , the use of daptomycin for culture-negative endocarditis is increasing. Daptomycin-induced acute eosinophilic pneumonia requires withdrawal of daptomycin and commencement of oral prednisolone. Careful prescription of oral antibiotics is needed in febrile patients with prosthetic valves.>., Competing Interests: None., (© 2021 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.)
Published: 2022
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48. A Phenotyping of Diastolic Function by Machine Learning Improves Prediction of Clinical Outcomes in Heart Failure.

Author: Kameshima H, Uejima T, Fraser AG, Takahashi L, Cho J, Suzuki S, Kato Y, Yajima J, and Yamashita T
Abstract: Background: Discriminating between different patterns of diastolic dysfunction in heart failure (HF) is still challenging. We tested the hypothesis that an unsupervised machine learning algorithm would detect heterogeneity in diastolic function and improve risk stratification compared with recommended consensus criteria. Methods: This study included 279 consecutive patients aged 24-97 years old with clinically stable HF referred for echocardiographic assessment, in whom diastolic variables were measured according to the current guidelines. Cluster analysis was undertaken to identify homogeneous groups of patients with similar profiles of the variables. Sequential Cox models were used to compare cluster-based classification with guidelines-based classification for predicting clinical outcomes. The primary endpoint was hospitalization for worsening HF. Results: The analysis identified three clusters with distinct properties of diastolic function that shared similarities with guidelines-based classification. The clusters were associated with brain natriuretic peptide level ( p < 0.001), hemoglobin concentration ( p = 0.017) and estimated glomerular filtration rate ( p = 0.001). During a mean follow-up period of 2.6 ± 2.0 years, 62 patients (22%) experienced the primary endpoint. Cluster-based classification predicted events with a hazard ratio 1.68 ( p = 0.019) that was independent from and incremental to the Meta-analysis Global Group in Chronic Heart Failure (MAGGIC) risk score for HF, and from left ventricular end-diastolic volume and global longitudinal strain, whereas guidelines-based classification did not retain its independent prognostic value (hazard ratio = 1.25, p = 0.202). Conclusion: Machine learning can identify patterns of diastolic function that better stratify the risk for decompensation than the current consensus recommendations in HF. Integrating this data-driven phenotyping may help in refining prognostication and optimizing treatment., Competing Interests: TU received a research funding from Hitachi. SS received a lecture fee from Daiichi-Sankyo and a research funding from Daiichi-Sankyo and Mitsubishi-Tanabe. TY has received a research funding from Daiichi-Sankyo, Bayer Healthcare, and Bristol Meyers Squibb and a remuneration from Daiichi-Sankyo, Pfizer, Bayer Healthcare, Bristol-Myers Squibb, Toa Eiyo, and Ono Pharmaceutical. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Kameshima, Uejima, Fraser, Takahashi, Cho, Suzuki, Kato, Yajima and Yamashita.)
Published: 2021
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49. Estimation of Pulmonary Arterial Wave Reflection by Echo-Doppler: A Preliminary Study in Dogs With Experimentally-Induced Acute Pulmonary Embolism.

Author: Yoshida T, Uejima T, Komeda S, Matsuura K, Uemura A, Hayama H, Yamashita T, Yilmaz Z, and Tanaka R
Abstract: Background: Pulmonary arterial (PA) wave reflection provides additional information for assessing right ventricular afterload, but its applications is hampered by the need for invasive pressure and flow measurements. We tested the hypothesis that PA pressure and flow waveforms estimated by Doppler echocardiography could be used to quantify PA wave reflection. Methods: Doppler echocardiographic images of tricuspid regurgitation and right ventricular outflow tract flow used to estimate PA pressure and flow waveforms were acquired simultaneously with direct measurements with a dual sensor-tipped catheter under various hemodynamic conditions in a canine model of pulmonary hypertension ( n = 8). Wave separation analysis was performed on echo-Doppler derived as well as catheter derived waveforms to separate PA pressure into forward (Pf) and backward (Pb) pressures and derive wave reflection coefficient (RC) defined as the ratio of peak Pb to peak Pf. Results: Wave reflection indices by echo-Doppler agreed well with corresponding indices by catheter (Pb: mean difference = 0.4 mmHg, 95% limits of agreement = -4.3 to 5.0 mmHg; RC: bias = 0.13, 95% limits of agreement = -0.25 to 0.26). RC correlated negatively with PA compliance. Conclusion: This echo-Doppler method yields reasonable measurement of reflected wave in the pulmonary circulation, paving the way to a more integrative assessment of pulmonary hemodynamics in the clinical setting., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Yoshida, Uejima, Komeda, Matsuura, Uemura, Hayama, Yamashita, Yilmaz and Tanaka.)
Published: 2021
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50. Reduction of influenza in Osaka, Japan during the COVID-19 outbreak: a population-based ORION registry study.

Author: Hirose T, Katayama Y, Tanaka K, Kitamura T, Nakao S, Tachino J, Nakao S, Nitta M, Iwami T, Fujimi S, Uejima T, Miyamoto Y, Baba T, Mizobata Y, Kuwagata Y, Shimazu T, and Matsuoka T
Abstract: Objectives: The spread of COVID-19 has affected the incidence of other infectious diseases, but there are no reports of studies using comprehensive regional population-based data to evaluate the impact of COVID-19 on influenza incidence. We attempted to evaluate the impact of COVID-19 on influenza using the population-based ORION (Osaka Emergency Information Research Intelligent Operation Network) registry., Methods: The ORION registry of emergency patients treated by emergency medical service (EMS) personnel was developed by the Osaka Prefecture government. From ORION, we included emergency patients with influenza using the ICD (International Statistical Classification of Diseases and Related Health Problems) 10 codes. Influenza incidence rate ratio (IRR) and associated 95% CI were calculated., Results: The number of influenza patients transported by EMS decreased during the COVID-19 pandemic. The IRR showed a substantial decrease in influenza patients in 2020 (IRR 2020/2018 0.39, 95% CI 0.37-0.41)., Conclusions: A comprehensive regional analysis using the population-based ORION registry confirmed that from January 2020, when the first confirmed cases of COVID-19 infection were reported in Osaka, Japan, the number of influenza patients transported by EMS decreased dramatically., Competing Interests: All authors report no conflicts of interest., (© 2021 The Author(s).)
Published: 2021
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