1. A new computed tomography‐based approach to quantify swallowing muscle volume by measuring tongue muscle area in a single slice
- Author
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Javier Hurtado‐Oliva, Aniek T. Zwart, Jeroen Vister, Anouk van derHoorn, Roel J.H.M. Steenbakkers, Inge Wegner, and Gyorgy B. Halmos
- Subjects
CT scan ,dysphagia ,head and neck cancer ,sarcopenia ,swallowing muscle ,Diseases of the musculoskeletal system ,RC925-935 ,Human anatomy ,QM1-695 - Abstract
Abstract Background Measuring the swallowing muscle mass with volume measurements is complex and time intensive; therefore, it is not used in clinical practice. However, it can be clinically relevant, for instance, in the case of sarcopenic dysphagia. The aim of the study was to develop a feasible and clinically applicable method to measure swallowing muscle mass. Methods Data from 10 head and neck cancer patients were collected from the Oncological Life Study data‐biobank of the University Medical Center Groningen. The pharyngeal constrictor, genioglossus, mylohyoid and geniohyoid complex muscles, as well as the tongue complex muscles, were delineated manually on routinely performed head and neck computed tomography scans. Axial and sagittal planes were used for volume and area measurements, respectively. Muscle density measurements were performed with and without Hounsfield unit thresholding. Correlations were assessed by Pearson correlation coefficients, and interobserver reliability was measured using intra‐class correlation coefficients (ICCs). Results Significant differences were observed between sagittal area measurements with and without Hounsfield unit thresholds for pharyngeal constrictor, tongue complex and the sum of the swallowing muscles (t > 6; P‐value
- Published
- 2024
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